WO1996026754A3 - Incrementing mechanism in particular for use with a membral syringe - Google Patents

Incrementing mechanism in particular for use with a membral syringe Download PDF

Info

Publication number
WO1996026754A3
WO1996026754A3 PCT/GB1996/000446 GB9600446W WO9626754A3 WO 1996026754 A3 WO1996026754 A3 WO 1996026754A3 GB 9600446 W GB9600446 W GB 9600446W WO 9626754 A3 WO9626754 A3 WO 9626754A3
Authority
WO
WIPO (PCT)
Prior art keywords
plunger
toothed wheel
syringe
rotation
thrust rod
Prior art date
Application number
PCT/GB1996/000446
Other languages
French (fr)
Other versions
WO1996026754A2 (en
Inventor
Bernard Sams
Original Assignee
Bernard Sams
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bernard Sams filed Critical Bernard Sams
Priority to EP96904187A priority Critical patent/EP0918555A2/en
Publication of WO1996026754A2 publication Critical patent/WO1996026754A2/en
Publication of WO1996026754A3 publication Critical patent/WO1996026754A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A mechanism for accurate dispensing of pre-set quantities of medicament from a syringe has a plunger (17) rotatable within a housing (13), which plunger (17) has a cam surface (19) engaged by a fixed follower (22) such that rotation of the plunger (17) moves the plunger away from the synringe. Internally within the plunger there is a number of parallel racks (40) each of which in turn comes into engagement with a first toothed wheel (47) on rotation of the plunger. The first toothed wheel (47) is connected to a second toothed wheel (48) which runs on a fixed rack (49) extending within the plunger parallel to the axis thereof. The first toothed wheel (47) is coupled to a thrust rod (44) for the piston (12) of the syringe. After pre-setting a required dose by rotation of the plunger (17), the plunger is then pushed towards the synringe, so rotating the first and second toothed wheels (47 and 48). This drives the thrust rod (44) into the syringe but by appropriate selection of the toothed wheel diameters and the tooth pitch thereof, an advantageous velocity ratio between the plunger and thrust rod movements may be obtained.
PCT/GB1996/000446 1995-02-28 1996-02-28 Incrementing mechanism in particular for use with a membral syringe WO1996026754A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP96904187A EP0918555A2 (en) 1995-02-28 1996-02-28 Incrementing mechanism in particular for use with a membral syringe

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9503969.9A GB9503969D0 (en) 1995-02-28 1995-02-28 Incrementing mechanism
GB9503969.9 1995-02-28

Publications (2)

Publication Number Publication Date
WO1996026754A2 WO1996026754A2 (en) 1996-09-06
WO1996026754A3 true WO1996026754A3 (en) 1996-10-17

Family

ID=10770369

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1996/000446 WO1996026754A2 (en) 1995-02-28 1996-02-28 Incrementing mechanism in particular for use with a membral syringe

Country Status (3)

Country Link
EP (1) EP0918555A2 (en)
GB (1) GB9503969D0 (en)
WO (1) WO1996026754A2 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8900204B2 (en) 2006-05-16 2014-12-02 Novo Nordisk A/S Gearing mechanism for an injection device
US9011391B2 (en) 2003-03-03 2015-04-21 Sanofi-Aventis Deutschland Gmbh Pen-type injector
US9022991B2 (en) 2000-06-16 2015-05-05 Novo Nordisk A/S Injection device
US9192727B2 (en) 2006-05-18 2015-11-24 Novo Nordisk A/S Injection device with mode locking means
US9205197B2 (en) 2003-03-03 2015-12-08 Sanofi-Aventis Deutschland Gmbh Drug delivery device dose setting mechanism
US9265893B2 (en) 2007-02-05 2016-02-23 Novo Nordisk A/S Injection button
US9533106B2 (en) 2011-12-29 2017-01-03 Novo Nordisk A/S Torsion-spring based wind-up auto injector pen with dial-up/dial-down mechanism
US11964141B2 (en) 2017-06-16 2024-04-23 Credence Medsystems, Inc. System and method for safety syringe

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6003736A (en) * 1997-06-09 1999-12-21 Novo Nordisk A/S Device for controlled dispensing of a dose of a liquid contained in a cartridge
US5957896A (en) * 1997-08-11 1999-09-28 Becton, Dickinson And Company Medication delivery pen
US6585699B2 (en) 2000-04-13 2003-07-01 Nna/S Drug delivery device provided with a one-way mechanism
GB0200444D0 (en) * 2002-01-10 2002-02-27 Owen Mumford Ltd Improvements relating to medical injection devices
EP1487520A1 (en) 2002-03-18 2004-12-22 Eli Lilly And Company Medication dispensing apparatus with gear set for mechanical advantage
GB0306642D0 (en) 2003-03-22 2003-04-30 Dca Design Int Ltd Improvements in and relating to an injector for a medical product
WO2005018721A1 (en) 2003-08-12 2005-03-03 Eli Lilly And Company Medication dispensing apparatus with triple screw threads for mechanical advantage
PT1732628E (en) 2004-03-30 2011-12-07 Lilly Co Eli Medication dispensing apparatus with gear set having drive member accommodating opening
PL1732629T3 (en) 2004-03-30 2019-10-31 Lilly Co Eli Medication dispensing apparatus with spring-driven locking feature enabled by administration of final dose
EP1804865B1 (en) 2004-10-21 2009-09-30 Novo Nordisk A/S Dial-down mechanism for wind-up pen
US20090043264A1 (en) * 2005-04-24 2009-02-12 Novo Nordisk A/S Injection Device
EP1923083A1 (en) 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Drive mechanisms for use in drug delivery devices
CA2574746A1 (en) * 2007-01-22 2008-07-22 Duoject Medical Systems Inc. Syringe having venting structure and method for mixing two substances in a syringe
JP4382115B2 (en) * 2007-07-10 2009-12-09 株式会社アイカムス・ラボ Cartridge type liquid injector
DE102007053742A1 (en) * 2007-11-12 2009-05-20 Tecpharma Licensing Ag Rotatable guide sleeve with over-tensioned spring
US8052645B2 (en) 2008-07-23 2011-11-08 Avant Medical Corp. System and method for an injection using a syringe needle
CA2724641C (en) 2008-05-20 2020-03-24 Avant Medical Corp. Autoinjector system
US8177749B2 (en) 2008-05-20 2012-05-15 Avant Medical Corp. Cassette for a hidden injection needle
US9186458B2 (en) * 2008-12-12 2015-11-17 Shl Group Ab Medicament delivery device
GB0823693D0 (en) 2008-12-31 2009-02-04 Owen Mumford Ltd Autoinjector
DK2414011T3 (en) 2009-04-01 2016-05-09 Shl Group Ab DRUG DELIVERY DEVICES
WO2011044294A1 (en) * 2009-10-06 2011-04-14 Flex Partners, Inc. Precision fluid delivery systems
EP2329857A1 (en) 2009-12-03 2011-06-08 Sanofi-Aventis Deutschland GmbH A drug delivery device
US9125942B2 (en) 2010-01-19 2015-09-08 Northwestern University Paramagnetic metal-nanodiamond conjugates
EP2468341A1 (en) * 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Auto-injector
CA2822981C (en) * 2010-12-27 2015-11-24 Showa Yakuhin Kako Co., Ltd. Anesthetic solution-filled cartridge-type electric dental syringe
US20120271100A1 (en) 2011-04-14 2012-10-25 Northwestern University Compositions and methods for the detection of zinc
LT2699293T (en) 2011-04-20 2019-04-25 Amgen Inc. Autoinjector apparatus
EP2823270B1 (en) 2012-03-09 2022-05-04 Promega Corporation pH SENSORS
US20140134665A1 (en) 2012-11-15 2014-05-15 Northwestern University Compositions and methods for the detection of zinc
USD898908S1 (en) 2012-04-20 2020-10-13 Amgen Inc. Pharmaceutical product cassette for an injection device
CN202699777U (en) * 2012-06-14 2013-01-30 甘肃成纪生物药业有限公司 Adjustable injection pen
SG11201504520XA (en) 2012-12-12 2015-07-30 Promega Corp Compositions and methods for capture of cellular targets of bioactive agents
GB2511806A (en) * 2013-03-14 2014-09-17 Norton Healthcare Ltd Dispensing mechanism for a medical device
CA2906249C (en) 2013-03-14 2018-01-02 Norton Healthcare Limited Dispensing mechanism for a medical device
CA2906245C (en) 2013-03-14 2019-04-30 Norton Healthcare Limited Dispensing mechanism for a medical device
AU2014236949C1 (en) 2013-03-15 2018-11-29 Promega Corporation Activation of bioluminescence by structural complementation
US10168323B2 (en) 2013-03-15 2019-01-01 Promega Corporation Compositions and methods for capture of cellular targets of bioactive agents
US10492990B2 (en) 2013-03-15 2019-12-03 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
JP6336564B2 (en) 2013-03-15 2018-06-06 アムゲン・インコーポレーテッド Drug cassette, auto-injector, and auto-injector system
CN106062565B (en) 2014-02-27 2018-06-08 宝洁公司 For assessing the method for the zinc of bioavailable
EP4159754A1 (en) 2014-05-15 2023-04-05 Cleveland Heartlab, Inc. Compositions and methods for purification and detection of hdl and apoa1
WO2016004333A2 (en) 2014-07-02 2016-01-07 Promega Corporation Reversible metal ion chelators
US9283363B1 (en) 2014-08-19 2016-03-15 Kablooe Design, Inc. Composition delivery device and methods of use
JP6814132B2 (en) 2014-09-12 2021-01-13 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ Internal protein tag
US10603441B2 (en) 2014-10-16 2020-03-31 Sanofi-Aventis Deutschland Gmbh Window element and drug delivery device
US10406249B2 (en) 2015-06-26 2019-09-10 Northwestern University Gd(III)-dithiolane gold nanoparticle conjugates
PE20211202A1 (en) 2017-08-24 2021-07-05 Novo Nordisk As COMPOSITIONS OF GLP-1 AND ITS USES
BR112020011830A2 (en) 2017-12-13 2020-11-24 Regeneron Pharmaceuticals, Inc. devices and methods for precision dose distribution
WO2020102446A2 (en) 2018-11-13 2020-05-22 Credence Medsystems, Inc. System and method for multiple site injection
JP2022526907A (en) 2019-03-20 2022-05-27 プロメガ コーポレイション Photoaffinity probe
US11360096B2 (en) 2019-05-16 2022-06-14 Duke University Complex BRET technique for measuring biological interactions
CN115427556A (en) 2019-11-27 2022-12-02 普洛麦格公司 Multipart luciferase peptides and polypeptides
PE20221575A1 (en) 2020-02-18 2022-10-06 Novo Nordisk As PHARMACEUTICAL FORMULATIONS
WO2021257911A1 (en) 2020-06-17 2021-12-23 Credence Medsystems, Inc. System and method for microdose injection
IT202100012020A1 (en) * 2021-05-11 2022-11-11 Stevanato Group Spa Drug injection device
WO2023215497A1 (en) 2022-05-04 2023-11-09 Promega Corporation Photoactivatable compounds and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991014467A1 (en) * 1990-03-29 1991-10-03 Bernard Sams Dispensing device

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991014467A1 (en) * 1990-03-29 1991-10-03 Bernard Sams Dispensing device

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9022991B2 (en) 2000-06-16 2015-05-05 Novo Nordisk A/S Injection device
US9533105B2 (en) 2003-03-03 2017-01-03 Sanofi-Aventis Deutschland Gmbh Drive mechanisms suitable for use in drug delivery devices
US9011391B2 (en) 2003-03-03 2015-04-21 Sanofi-Aventis Deutschland Gmbh Pen-type injector
US9205197B2 (en) 2003-03-03 2015-12-08 Sanofi-Aventis Deutschland Gmbh Drug delivery device dose setting mechanism
US9233211B2 (en) 2003-03-03 2016-01-12 Sanofi-Aventis Deutschland Gmbh Relating to a pen-type injector
US9561331B2 (en) 2003-03-03 2017-02-07 Sanofi-Aventis Deutschland Gmbh Drive mechanisms suitable for use in drug delivery devices
US9408979B2 (en) 2003-03-03 2016-08-09 Sanofi-Aventis Deutschland Gmbh Pen-type injector
US9526844B2 (en) 2003-03-03 2016-12-27 Sanofi-Aventis Deutschland Gmbh Pen-type injector
US8900204B2 (en) 2006-05-16 2014-12-02 Novo Nordisk A/S Gearing mechanism for an injection device
US9192727B2 (en) 2006-05-18 2015-11-24 Novo Nordisk A/S Injection device with mode locking means
US9265893B2 (en) 2007-02-05 2016-02-23 Novo Nordisk A/S Injection button
US9533106B2 (en) 2011-12-29 2017-01-03 Novo Nordisk A/S Torsion-spring based wind-up auto injector pen with dial-up/dial-down mechanism
US11964141B2 (en) 2017-06-16 2024-04-23 Credence Medsystems, Inc. System and method for safety syringe

Also Published As

Publication number Publication date
GB9503969D0 (en) 1995-04-19
WO1996026754A2 (en) 1996-09-06
EP0918555A2 (en) 1999-06-02

Similar Documents

Publication Publication Date Title
WO1996026754A3 (en) Incrementing mechanism in particular for use with a membral syringe
JP4361236B2 (en) Dose setting limiter
CA2119913A1 (en) Large dose pen
AU8011098A (en) Syringe comprising a tiltable nut
EP0927058B2 (en) Syringe
CA2222411A1 (en) A syringe with an exchangeable cartridge
NZ302558A (en) Dispensing apparatus with a medication cartridge with a manually adjustable metering mechanism
CA2412229A1 (en) An injection device with a gearbox
IL135079A0 (en) Syringe for dosed injection of a medicine
US20190269858A1 (en) Multi-channel rotary encoder
CA2231481A1 (en) Pen-type injector drive mechanism
AU569862B2 (en) Syringe to dispense measured volumes
RU2003101065A (en) INJECTION DEVICE WITH REDUCER
GB9218193D0 (en) Gear pump with a delivery rate depending non-linearly on the rate of revolutions
ES272012U (en) Dispensing and metering device for viscous products.
WO1997001362A3 (en) Dosing syringe
JPS63278745A (en) Index
EP1759727A1 (en) Infusion device having a control unit
SU1428884A1 (en) Ratchet-and-pawl mechanism
UA13757A (en) Device for axial terminal-radio parts calibration by electric parameters
ES289349U (en) Dosage device for pastose products (Machine-translation by Google Translate, not legally binding)
MXPA99001618A (en) Syringe comprising a tiltable nut

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

AK Designated states

Kind code of ref document: A3

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
ENP Entry into the national phase

Ref country code: US

Ref document number: 1997 875210

Date of ref document: 19970828

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 1996904187

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1996904187

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1996904187

Country of ref document: EP