WO1996036339A3 - Use of dihydrotestosterone compounds for treating male sexual dysfunction - Google Patents

Use of dihydrotestosterone compounds for treating male sexual dysfunction Download PDF

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Publication number
WO1996036339A3
WO1996036339A3 PCT/US1996/006078 US9606078W WO9636339A3 WO 1996036339 A3 WO1996036339 A3 WO 1996036339A3 US 9606078 W US9606078 W US 9606078W WO 9636339 A3 WO9636339 A3 WO 9636339A3
Authority
WO
WIPO (PCT)
Prior art keywords
dihydrotestosterone
sexual dysfunction
compounds
male sexual
treating male
Prior art date
Application number
PCT/US1996/006078
Other languages
French (fr)
Other versions
WO1996036339A2 (en
Inventor
Christo S Mantzoros
Original Assignee
Beth Israel Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beth Israel Hospital filed Critical Beth Israel Hospital
Priority to AU56714/96A priority Critical patent/AU5671496A/en
Priority to EP96913887A priority patent/EP0827405A2/en
Publication of WO1996036339A2 publication Critical patent/WO1996036339A2/en
Publication of WO1996036339A3 publication Critical patent/WO1996036339A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

A method for treating sexual dysfunction in a subject, comprising increasing dihydrotestosterone (DHT) concentrations in the subject to effectively treat the sexual dysfunction is disclosed. Methods of the invention can be used for prophylactic and/or therapeutic treatment of sexual dysfunctions.
PCT/US1996/006078 1995-05-15 1996-05-01 Use of dihydrotestosterone compounds for treating male sexual dysfunction WO1996036339A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU56714/96A AU5671496A (en) 1995-05-15 1996-05-01 Use of dihydrotestosterone compounds for treating male sexual dysfunction
EP96913887A EP0827405A2 (en) 1995-05-15 1996-05-01 Use of dihydrotestosterone compounds for treating male sexual dysfunction

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US44072695A 1995-05-15 1995-05-15
US08/440,726 1995-05-15
US48747195A 1995-06-07 1995-06-07
US08/487,471 1995-06-07

Publications (2)

Publication Number Publication Date
WO1996036339A2 WO1996036339A2 (en) 1996-11-21
WO1996036339A3 true WO1996036339A3 (en) 1997-02-13

Family

ID=27032530

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/006078 WO1996036339A2 (en) 1995-05-15 1996-05-01 Use of dihydrotestosterone compounds for treating male sexual dysfunction

Country Status (4)

Country Link
EP (1) EP0827405A2 (en)
AU (1) AU5671496A (en)
CA (1) CA2219082A1 (en)
WO (1) WO1996036339A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9125816B2 (en) 2000-08-30 2015-09-08 Besins Healthcare Inc. Pharmaceutical composition and method for treating hypogonadism

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0409498D0 (en) * 2004-04-28 2004-06-02 Hunter Fleming Ltd Transdermal steroid formulation
PT1750766E (en) 2004-05-11 2013-09-30 Emotional Brain Bv Pharmaceutical formulations and uses thereof in the treatment of female sexual dysfunction
EP1790343A1 (en) 2005-11-11 2007-05-30 Emotional Brain B.V. Pharmaceuticals formulations and uses thereof in the treatment of female sexual dysfunction
EP1925307A1 (en) 2006-11-03 2008-05-28 Emotional Brain B.V. Use of 3-alpha-androstanediol in the treatment of sexual dysfunction

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
A.D. MOORADIAN ET AL.: "Biological actions of androgens.", ENDOCR. REV., vol. 8, no. 1, 1987, pages 1 - 28, XP000612870 *
G.R. CUNNINGHAM ET AL.: "Testosterone replacement therapy and sleep-related erections in hypogonadal men.", J. CLIN. ENDOCRINOL. METAB., vol. 70, no. 3, 1990, pages 792 - 797, XP000612829 *
J.M. DAVIDSON ET AL.: "Hormonal replacement and sexuality in men.", CLIN. ENDOCRINOL. METAB., vol. 11, no. 3, 1982, pages 599 - 623, XP000612869 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9125816B2 (en) 2000-08-30 2015-09-08 Besins Healthcare Inc. Pharmaceutical composition and method for treating hypogonadism
US9132089B2 (en) 2000-08-30 2015-09-15 Besins Healthcare Inc. Pharmaceutical composition and method for treating hypogonadism

Also Published As

Publication number Publication date
CA2219082A1 (en) 1996-11-21
WO1996036339A2 (en) 1996-11-21
AU5671496A (en) 1996-11-29
EP0827405A2 (en) 1998-03-11

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