WO1996036368A3 - Composite materials using bone bioactive glass and ceramic fibers - Google Patents

Composite materials using bone bioactive glass and ceramic fibers Download PDF

Info

Publication number
WO1996036368A3
WO1996036368A3 PCT/US1996/006439 US9606439W WO9636368A3 WO 1996036368 A3 WO1996036368 A3 WO 1996036368A3 US 9606439 W US9606439 W US 9606439W WO 9636368 A3 WO9636368 A3 WO 9636368A3
Authority
WO
WIPO (PCT)
Prior art keywords
fibers
bioactive
bone
bioactive glass
structural
Prior art date
Application number
PCT/US1996/006439
Other languages
French (fr)
Other versions
WO1996036368A2 (en
Inventor
Michele S Marcolongo
Paul Ducheyne
Frank Ko
William Lacourse
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/463,009 external-priority patent/US5721049A/en
Priority claimed from US08/461,109 external-priority patent/US6121172A/en
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Priority to JP53488196A priority Critical patent/JPH11506948A/en
Priority to EP19960915566 priority patent/EP0871504B1/en
Priority to AT96915566T priority patent/ATE226098T1/en
Priority to AU57313/96A priority patent/AU701236B2/en
Priority to DE1996624376 priority patent/DE69624376T2/en
Publication of WO1996036368A2 publication Critical patent/WO1996036368A2/en
Publication of WO1996036368A3 publication Critical patent/WO1996036368A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C4/00—Compositions for glass with special properties
    • C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30965—Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/36—Femoral heads ; Femoral endoprostheses
    • A61F2/3662—Femoral shafts
    • A61F2/367—Proximal or metaphyseal parts of shafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/422—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/443—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with carbon fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C13/00—Fibre or filament compositions
    • D—TEXTILES; PAPER
    • D03—WEAVING
    • D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
    • D03D15/00—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used
    • D03D15/20—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used characterised by the material of the fibres or filaments constituting the yarns or threads
    • D03D15/242—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used characterised by the material of the fibres or filaments constituting the yarns or threads inorganic, e.g. basalt
    • D03D15/267—Glass
    • D—TEXTILES; PAPER
    • D03—WEAVING
    • D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
    • D03D15/00—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used
    • D03D15/20—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used characterised by the material of the fibres or filaments constituting the yarns or threads
    • D03D15/242—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used characterised by the material of the fibres or filaments constituting the yarns or threads inorganic, e.g. basalt
    • D03D15/275—Carbon fibres
    • D—TEXTILES; PAPER
    • D03—WEAVING
    • D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
    • D03D15/00—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used
    • D03D15/50—Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used characterised by the properties of the yarns or threads
    • D—TEXTILES; PAPER
    • D03—WEAVING
    • D03D—WOVEN FABRICS; METHODS OF WEAVING; LOOMS
    • D03D9/00—Open-work fabrics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108—Shapes
    • A61F2002/30199—Three-dimensional shapes
    • A61F2002/30289—Three-dimensional shapes helically-coiled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3082—Grooves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0091—Three-dimensional shapes helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C2213/00—Glass fibres or filaments
    • C03C2213/02—Biodegradable glass fibres
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2101/00—Inorganic fibres
    • D10B2101/02—Inorganic fibres based on oxides or oxide ceramics, e.g. silicates
    • D10B2101/06—Glass
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2101/00—Inorganic fibres
    • D10B2101/02—Inorganic fibres based on oxides or oxide ceramics, e.g. silicates
    • D10B2101/08—Ceramic
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2101/00—Inorganic fibres
    • D10B2101/10—Inorganic fibres based on non-oxides other than metals
    • D10B2101/12—Carbon; Pitch
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00—Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • D10B2331/02—Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyamides
    • D10B2331/021—Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyamides aromatic polyamides, e.g. aramides
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00—Physical properties
    • D10B2401/04—Heat-responsive characteristics
    • D10B2401/041—Heat-responsive characteristics thermoplastic; thermosetting
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00—Physical properties
    • D10B2401/06—Load-responsive characteristics
    • D10B2401/061—Load-responsive characteristics elastic
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00—Physical properties
    • D10B2401/06—Load-responsive characteristics
    • D10B2401/063—Load-responsive characteristics high strength
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2509/00—Medical; Hygiene
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2929—Bicomponent, conjugate, composite or collateral fibers or filaments [i.e., coextruded sheath-core or side-by-side type]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2929—Bicomponent, conjugate, composite or collateral fibers or filaments [i.e., coextruded sheath-core or side-by-side type]
    • Y10T428/2931—Fibers or filaments nonconcentric [e.g., side-by-side or eccentric, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2933—Coated or with bond, impregnation or core
    • Y10T428/2964—Artificial fiber or filament
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2933—Coated or with bond, impregnation or core
    • Y10T428/2964—Artificial fiber or filament
    • Y10T428/2965—Cellulosic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2933—Coated or with bond, impregnation or core
    • Y10T428/2964—Artificial fiber or filament
    • Y10T428/2967—Synthetic resin or polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2933—Coated or with bond, impregnation or core
    • Y10T428/2964—Artificial fiber or filament
    • Y10T428/2967—Synthetic resin or polymer
    • Y10T428/2969—Polyamide, polyimide or polyester
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2973—Particular cross section
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913—Rod, strand, filament or fiber
    • Y10T428/2973—Particular cross section
    • Y10T428/2978—Surface characteristic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/30—Self-sustaining carbon mass or layer with impregnant or other layer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/30—Woven fabric [i.e., woven strand or strip material]
    • Y10T442/3049—Including strand precoated with other than free metal or alloy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/30—Woven fabric [i.e., woven strand or strip material]
    • Y10T442/3179—Woven fabric is characterized by a particular or differential weave other than fabric in which the strand denier or warp/weft pick count is specified
    • Y10T442/322—Warp differs from weft
    • Y10T442/3228—Materials differ
    • Y10T442/3236—Including inorganic strand material

Abstract

Composite materials formed from bone bioactive glass or ceramic fibers and structural fibers are disclosed. In preferred embodiments, a braid or mesh of interwoven bone bioactive glass or ceramic fibers and structural fibers is impregnated with a polymeric material to provide a composite of suitable biocompatibility and structural integrity. Most preferably, the mesh or braid is designed so that the bioactive fibers are concentrated at the surface of the implant to create a surface comprised of at least 30% bioactive material, thereby providing enhanced bone ingrowth. The interweaving between the bone bioactive glass or ceramic fibers and the core of structural fibers overcomes the problems found in prior composite systems where the bioactive material delaminates from the polymer. Preferred bioactive materials include calcium phosphate ceramics and preferred structural fibers include carbon fibers. Improved prosthetic implants and methods of affixing an implant are thus also disclosed.
PCT/US1996/006439 1993-11-15 1996-05-08 Composite materials using bone bioactive glass and ceramic fibers WO1996036368A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP53488196A JPH11506948A (en) 1993-11-15 1996-05-08 Composite using bioactive glass and ceramic fibers for bone
EP19960915566 EP0871504B1 (en) 1993-11-15 1996-05-08 Composite materials using bone bioactive glass and ceramic fibers
AT96915566T ATE226098T1 (en) 1993-11-15 1996-05-08 COMPOSITE MATERIAL USING BONE BIOACTIVE GLASS AND CERAMIC FIBERS
AU57313/96A AU701236B2 (en) 1993-11-15 1996-05-08 Composite materials using bone bioactive glass and ceramic fibers
DE1996624376 DE69624376T2 (en) 1993-11-15 1996-05-08 COMPOSITE MATERIAL THAT USES BONE BIOACTIVE GLASS AND CERAMIC FIBERS

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US08/152,962 US5468544A (en) 1993-11-15 1993-11-15 Composite materials using bone bioactive glass and ceramic fibers
US08/436,585 1995-05-08
US08/436,585 US5645934A (en) 1993-11-15 1995-05-08 Composite materials using bone bioactive glass and ceramic fibers
US46342895A 1995-06-05 1995-06-05
US08/463,428 1995-06-05
US08/463,009 US5721049A (en) 1993-11-15 1995-06-05 Composite materials using bone bioactive glass and ceramic fibers
US08/461,109 1995-06-05
US08/461,109 US6121172A (en) 1993-11-15 1995-06-05 Composite materials using bone bioactive glass and ceramic fibers
US08/463,009 1995-06-05

Publications (2)

Publication Number Publication Date
WO1996036368A2 WO1996036368A2 (en) 1996-11-21
WO1996036368A3 true WO1996036368A3 (en) 1996-12-19

Family

ID=27538444

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US1994/013152 WO1995014127A1 (en) 1993-11-15 1994-11-14 Composite materials using bone bioactive glass and ceramic fibers
PCT/US1996/006439 WO1996036368A2 (en) 1993-11-15 1996-05-08 Composite materials using bone bioactive glass and ceramic fibers

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US1994/013152 WO1995014127A1 (en) 1993-11-15 1994-11-14 Composite materials using bone bioactive glass and ceramic fibers

Country Status (10)

Country Link
US (2) US5468544A (en)
EP (2) EP0730681B1 (en)
JP (2) JPH09505345A (en)
AT (2) ATE222735T1 (en)
AU (1) AU701236B2 (en)
CA (2) CA2176707A1 (en)
DE (2) DE69431254T2 (en)
ES (2) ES2181762T3 (en)
IL (1) IL111446A (en)
WO (2) WO1995014127A1 (en)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2326997A (en) * 1996-03-18 1997-10-10 Trustees Of The University Of Pennsylvania, The Bioactive material substrate for enhanced cellular attachment and function
WO1997041079A1 (en) * 1996-05-01 1997-11-06 Usbiomaterials Bioactive ceramics and method of preparing bioactive ceramics
DE69738492T2 (en) * 1996-09-30 2009-01-15 Brainbase Corp. Implant with bioactive particles and process for its preparation
US6602293B1 (en) * 1996-11-01 2003-08-05 The Johns Hopkins University Polymeric composite orthopedic implant
JP3275032B2 (en) * 1997-03-03 2002-04-15 独立行政法人産業技術総合研究所 Environmental purification material and method for producing the same
AU1942099A (en) 1997-12-19 1999-07-12 Us Biomaterials Corporation Tape cast multi-layer ceramic/metal composites
FI110063B (en) * 1998-12-11 2002-11-29 Antti Yli-Urpo New bioactive product and its use
US6147135A (en) 1998-12-31 2000-11-14 Ethicon, Inc. Fabrication of biocompatible polymeric composites
US6383519B1 (en) * 1999-01-26 2002-05-07 Vita Special Purpose Corporation Inorganic shaped bodies and methods for their production and use
GB9902976D0 (en) * 1999-02-11 1999-03-31 Giltech Ltd Composite
US6667049B2 (en) 1999-06-14 2003-12-23 Ethicon, Inc. Relic process for producing bioresorbable ceramic tissue scaffolds
US6458162B1 (en) * 1999-08-13 2002-10-01 Vita Special Purpose Corporation Composite shaped bodies and methods for their production and use
US6451059B1 (en) 1999-11-12 2002-09-17 Ethicon, Inc. Viscous suspension spinning process for producing resorbable ceramic fibers and scaffolds
WO2001072145A1 (en) 2000-03-24 2001-10-04 Ustherapeutics, Llc Nutritional supplements formulated from bioactive materials
US6736799B1 (en) 2000-10-24 2004-05-18 Vita Licensing, Inc. Delivery device for biological composites and method of preparation thereof
US7052517B2 (en) * 2000-10-24 2006-05-30 Vita Special Purpose Corporation Delivery device for biological composites and method of preparation thereof
US7005135B2 (en) * 2001-01-30 2006-02-28 Ethicon Inc. Glass scaffolds with controlled resorption rates and methods for making same
US20020115742A1 (en) * 2001-02-22 2002-08-22 Trieu Hai H. Bioactive nanocomposites and methods for their use
FI117963B (en) * 2001-04-26 2007-05-15 Eija Marjut Pirhonen Material that replaces bone
EP1406680A4 (en) * 2001-06-15 2007-01-10 Johns Hopkins Singapore Pte Lt Biofunctional fibers
US7303817B2 (en) 2001-10-24 2007-12-04 Weitao Jia Dental filling material
US7204874B2 (en) 2001-10-24 2007-04-17 Pentron Clinical Technologies, Llc Root canal filling material
US7750063B2 (en) 2001-10-24 2010-07-06 Pentron Clinical Technologies, Llc Dental filling material
CN100347114C (en) * 2001-12-12 2007-11-07 罗克伍尔国际公司 Fibres and their production
US20030220692A1 (en) * 2002-02-09 2003-11-27 Shapiro Irving M. Preparations of nucleus pulposus cells and methods for their generation, identification, and use
AU2003251899A1 (en) * 2002-07-10 2004-01-23 University Of Florida Sol-gel derived bioactive glass polymer composite
US7066962B2 (en) 2002-07-23 2006-06-27 Porex Surgical, Inc. Composite surgical implant made from macroporous synthetic resin and bioglass particles
EP1549359A2 (en) * 2002-10-08 2005-07-06 Osteotech, Inc. Coupling agents for orthopedic biomaterials
US20050118236A1 (en) * 2002-12-03 2005-06-02 Gentis Inc. Bioactive, resorbable scaffolds for tissue engineering
KR20050088380A (en) * 2002-12-12 2005-09-05 오스테오테크, 인코포레이티드 Formable and settable polymer bone composite and method of production thereof
US8012210B2 (en) 2004-01-16 2011-09-06 Warsaw Orthopedic, Inc. Implant frames for use with settable materials and related methods of use
US7854756B2 (en) * 2004-01-22 2010-12-21 Boston Scientific Scimed, Inc. Medical devices
US7189263B2 (en) * 2004-02-03 2007-03-13 Vita Special Purpose Corporation Biocompatible bone graft material
US7189409B2 (en) * 2004-03-09 2007-03-13 Inion Ltd. Bone grafting material, method and implant
DE102004012411A1 (en) * 2004-03-13 2005-09-29 Dot Gmbh Composite materials based on polysilicic acids and process for their preparation
US9220595B2 (en) 2004-06-23 2015-12-29 Orthovita, Inc. Shapeable bone graft substitute and instruments for delivery thereof
JP4975741B2 (en) * 2005-05-26 2012-07-11 ジマー デンタル， インコーポレイテッド Artificial dental prosthesis
US8814567B2 (en) 2005-05-26 2014-08-26 Zimmer Dental, Inc. Dental implant prosthetic device with improved osseointegration and esthetic features
US8562346B2 (en) 2005-08-30 2013-10-22 Zimmer Dental, Inc. Dental implant for a jaw with reduced bone volume and improved osseointegration features
EP1928346B1 (en) 2005-08-30 2016-05-04 Zimmer Dental, Inc. Dental implant with improved osseointegration features
EP1976459A4 (en) 2006-01-19 2012-06-20 Warsaw Orthopedic Inc Porous osteoimplant
WO2007084725A2 (en) 2006-01-19 2007-07-26 Osteotech, Inc. Injectable and moldable bone substitute materials
GB0612028D0 (en) * 2006-06-16 2006-07-26 Imp Innovations Ltd Bioactive glass
WO2008002682A2 (en) 2006-06-29 2008-01-03 Orthovita, Inc. Bioactive bone graft substitute
US8968797B2 (en) * 2006-09-25 2015-03-03 Orthovita, Inc. Bioactive load-bearing composites
WO2009009020A1 (en) 2007-07-12 2009-01-15 Discgenics Human disc tissue
US20090061389A1 (en) 2007-08-30 2009-03-05 Matthew Lomicka Dental implant prosthetic device with improved osseointegration and shape for resisting rotation
KR100890935B1 (en) 2008-04-30 2009-04-02 한국지질자원연구원 Bioactive composition using peek and cao-sio2 for artificial bone and method for manufacture thereof
GB2475799A (en) * 2008-05-27 2011-06-01 Imp Innovations Ltd Hypoxia inducing factor (hif) stabilising glasses
US9095396B2 (en) 2008-07-02 2015-08-04 Zimmer Dental, Inc. Porous implant with non-porous threads
US8231387B2 (en) 2008-07-02 2012-07-31 Zimmer, Inc. Porous implant with non-porous threads
US8562348B2 (en) 2008-07-02 2013-10-22 Zimmer Dental, Inc. Modular implant with secured porous portion
US8899982B2 (en) 2008-07-02 2014-12-02 Zimmer Dental, Inc. Implant with structure for securing a porous portion
GB0819055D0 (en) * 2008-10-17 2008-11-26 Invibio Ltd Polymeric materials
US20100114314A1 (en) 2008-11-06 2010-05-06 Matthew Lomicka Expandable bone implant
US20100168798A1 (en) 2008-12-30 2010-07-01 Clineff Theodore D Bioactive composites of polymer and glass and method for making same
US20130273500A1 (en) * 2009-02-02 2013-10-17 Thierry Giorno Dental Implant and Method for Rapid Integration
EP2243749B1 (en) * 2009-04-23 2015-04-08 PURAC Biochem BV Resorbable and biocompatible fibre glass compositions and their uses
GB0911365D0 (en) 2009-06-30 2009-08-12 Bioceramic Therapeutics Ltd Multicomponent glasses for use as coatings and in personal care products
US20110206828A1 (en) * 2009-07-10 2011-08-25 Bio2 Technologies, Inc. Devices and Methods for Tissue Engineering
US9775721B2 (en) 2009-07-10 2017-10-03 Bio2 Technologies, Inc. Resorbable interbody device
US9707058B2 (en) 2009-07-10 2017-07-18 Zimmer Dental, Inc. Patient-specific implants with improved osseointegration
BR112012000327B8 (en) 2009-07-10 2023-05-16 Bio2 Tech Inc METHOD OF MANUFACTURING A SYNTHETIC BONE PROSTHESIS AND SYNTHETIC BONE PROSTHESIS
US9399086B2 (en) * 2009-07-24 2016-07-26 Warsaw Orthopedic, Inc Implantable medical devices
EP2493425B1 (en) * 2009-10-29 2016-10-05 Prosidyan, Inc. Dynamic bioactive bone graft material and methods for handling
US8602782B2 (en) 2009-11-24 2013-12-10 Zimmer Dental, Inc. Porous implant device with improved core
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
RU2609870C2 (en) * 2011-07-13 2017-02-06 КАДОРЕЛЬ Катрин Composite part to endosseous implantation and method of said part making
RU2507306C1 (en) * 2012-09-04 2014-02-20 Открытое акционерное общество "Концерн "Центральный научно-исследовательский институт "Электроприбор" Sputtering unit of coatings onto precision parts of assemblies of gyroscopic instruments
US10252945B2 (en) 2012-09-26 2019-04-09 Multiple Energy Technologies Llc Bioceramic compositions
BR102013020961A2 (en) 2013-08-12 2016-03-08 Univ Fed De São Carlos vitreous composition, bioactive vitreous fibers and tissues and articles
EA201692098A1 (en) 2014-05-05 2017-05-31 МАЛТИПЛ ЭНЕРДЖИ ТЕКНОЛОДЖИС ЭлЭлСи BIOCERAMIC COMPOSITIONS AND THEIR APPLICATION FOR BIOMODULATION
USD766597S1 (en) 2014-06-27 2016-09-20 Multiple Energies Technologies Llc Apparel with bioceramic surface ornamentation
US9566368B2 (en) * 2014-11-13 2017-02-14 Bioventus, Llc Moldable bone graft compositions
AU2015370600B2 (en) * 2014-12-26 2020-07-23 Ossio Ltd Continuous-fiber reinforced biocomposite medical implants
KR101854648B1 (en) * 2016-05-04 2018-06-20 한국세라믹기술원 Bioactive glass fabric type bone morphogen and manufacturing method of the same
KR102000455B1 (en) * 2017-06-02 2019-07-16 한국세라믹기술원 Fabric type bone morphogen comprising bioactive glass fiber and manufacturing method of the same
KR102005757B1 (en) * 2017-06-02 2019-07-31 한국세라믹기술원 Bio ceramic for structural body comprising bioactive glass fiber and manufacturing method of the same
DE102020116929A1 (en) 2020-06-26 2021-12-30 Universität Rostock Endoprosthesis, method for the production thereof and use of an endoprosthesis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4131597A (en) * 1975-01-17 1978-12-26 Ernst Leitz Gmbh Bioactive composite material process of producing and method of using same
US4604097A (en) * 1985-02-19 1986-08-05 University Of Dayton Bioabsorbable glass fibers for use in the reinforcement of bioabsorbable polymers for bone fixation devices and artificial ligaments

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038703A (en) * 1975-11-14 1977-08-02 General Atomic Company Prosthetic devices having a region of controlled porosity
DE2620907C3 (en) * 1976-05-12 1984-09-20 Battelle-Institut E.V., 6000 Frankfurt Anchoring for highly stressed endoprostheses
DE2724814C3 (en) * 1977-06-02 1980-03-27 Kulzer & Co Gmbh, 6380 Bad Homburg Preliminary product for the preparation of bone cement
US4411027A (en) * 1979-04-27 1983-10-25 University Of Medicine And Dentistry Of New Jersey Bio-absorbable composite tissue scaffold
US4329743A (en) * 1979-04-27 1982-05-18 College Of Medicine And Dentistry Of New Jersey Bio-absorbable composite tissue scaffold
DE3042003A1 (en) * 1980-10-10 1982-07-15 Hans Dr. 5609 Hückeswagen Reimer Bone cement reinforcing component - comprises thread structure compatible with body tissue forming soft sponge
US4725234A (en) * 1985-08-15 1988-02-16 Ethridge Edwin C Alveolar bone grafting process with controlled surface active ceramics
US4781183A (en) * 1986-08-27 1988-11-01 American Cyanamid Company Surgical prosthesis
IT1240938B (en) * 1990-02-08 1993-12-27 S.E.I.P.I. Societa' Esportazione Importazione Prodotti Industriali BIOACTIVE GLASS COMPOSITION FOR BONE IMPLANTS AND PRODUCTS OBTAINED WITH SUCH A COMPOSITION OR THAT INCLUDE IT
EP0672117A4 (en) * 1992-08-13 1996-06-12 Univ Pennsylvania BIOACTIVE MATERIAL TEMPLATE FOR -i(IN VITRO) SYNTHESIS OF BONE TISSUE.
JPH06116114A (en) * 1992-10-09 1994-04-26 Nikon Corp Bone-filling material

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4131597A (en) * 1975-01-17 1978-12-26 Ernst Leitz Gmbh Bioactive composite material process of producing and method of using same
US4604097A (en) * 1985-02-19 1986-08-05 University Of Dayton Bioabsorbable glass fibers for use in the reinforcement of bioabsorbable polymers for bone fixation devices and artificial ligaments
US4604097B1 (en) * 1985-02-19 1991-09-10 Univ Dayton

Also Published As

Publication number Publication date
AU1056495A (en) 1995-06-06
ATE222735T1 (en) 2002-09-15
AU700443B2 (en) 1999-01-07
US5645934A (en) 1997-07-08
AU701236B2 (en) 1999-01-21
AU5731396A (en) 1996-11-29
ES2181762T3 (en) 2003-03-01
EP0730681A4 (en) 1998-07-15
ATE226098T1 (en) 2002-11-15
ES2186780T3 (en) 2003-05-16
US5468544A (en) 1995-11-21
DE69431254D1 (en) 2002-10-02
DE69624376T2 (en) 2003-07-03
DE69624376D1 (en) 2002-11-21
EP0730681A1 (en) 1996-09-11
EP0730681B1 (en) 2002-08-28
IL111446A0 (en) 1994-12-29
EP0871504A4 (en) 2000-08-16
IL111446A (en) 1998-09-24
EP0871504B1 (en) 2002-10-16
EP0871504A2 (en) 1998-10-21
CA2176707A1 (en) 1995-05-26
JPH11506948A (en) 1999-06-22
DE69431254T2 (en) 2003-04-30
WO1995014127A1 (en) 1995-05-26
JPH09505345A (en) 1997-05-27
CA2218086A1 (en) 1996-11-21
WO1996036368A2 (en) 1996-11-21

Similar Documents

Publication Publication Date Title
WO1996036368A3 (en) Composite materials using bone bioactive glass and ceramic fibers
DE3378303D1 (en) Polymeric acrylic prosthesis
PL301514A1 (en) Cavernous endoprostheses with a filling conductive to accretion of broken bones
CA2082427A1 (en) Prosthetic intervertebral disc
MX9603249A (en) Bioremodelable collagen graft prosthesis.
DE3567803D1 (en) Surgical element
DK2055267T3 (en) Beam permeable bone graft
EP1516602A3 (en) Implant with bioactive particles stuck and method of manufacturing the same
ATE415983T1 (en) ORTHOPEDIC PROSTHESIS WITH COMPOSITE COATING
GB2302656A (en) A biomaterial and bone implant for bone repair and replacement
EP0519293A3 (en) Implant material
ES2005049A6 (en) Surgical biocomposite material and a method for producing the material.
HUT59614A (en) Osetoplastical implantation material and method for producing same
EP0269745A4 (en) Bone prosthesis.
JPS5618864A (en) Bone transplantation member for dental prosthesis and bone connecting element and its manufacture
AU4950099A (en) Material for bone reconstruction
GB2268064B (en) Discontinuous fibre composite implant prosthesis
Marcolongo et al. Composite materials using bone bioactive glass and ceramic fibers
WO1999030672A8 (en) Coating material for prostheses and prosthetic parts
AU7133991A (en) Fatigue resistant orthopaedic implant and method of manufacture
ES8406873A1 (en) Polymeric prosthetic device with biocompatible carbonaceous coating
Nagai Implant Material

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU CA JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
ENP Entry into the national phase

Ref document number: 2218086

Country of ref document: CA

Ref country code: CA

Ref document number: 2218086

Kind code of ref document: A

Format of ref document f/p: F

ENP Entry into the national phase

Ref country code: JP

Ref document number: 1996 534881

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 1996915566

Country of ref document: EP

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWP Wipo information: published in national office

Ref document number: 1996915566

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 1996915566

Country of ref document: EP