WO1996041987A3 - High pressure gas exchanger - Google Patents

High pressure gas exchanger Download PDF

Info

Publication number
WO1996041987A3
WO1996041987A3 PCT/US1996/008424 US9608424W WO9641987A3 WO 1996041987 A3 WO1996041987 A3 WO 1996041987A3 US 9608424 W US9608424 W US 9608424W WO 9641987 A3 WO9641987 A3 WO 9641987A3
Authority
WO
WIPO (PCT)
Prior art keywords
gas
liquid
contacting members
high pressure
reservoir
Prior art date
Application number
PCT/US1996/008424
Other languages
French (fr)
Other versions
WO1996041987A2 (en
Inventor
James R Spears
Original Assignee
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wayne State filed Critical Univ Wayne State
Priority to AU59702/96A priority Critical patent/AU5970296A/en
Priority to JP50310897A priority patent/JP3848370B2/en
Priority to DE69630223T priority patent/DE69630223T2/en
Priority to EP96916998A priority patent/EP0838010B1/en
Publication of WO1996041987A2 publication Critical patent/WO1996041987A2/en
Publication of WO1996041987A3 publication Critical patent/WO1996041987A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/54—Mixing with gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/168—Sterilisation or cleaning before or after use
    • A61M1/169—Sterilisation or cleaning before or after use using chemical substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698—Blood oxygenators with or without heat-exchangers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/32—Oxygenators without membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/2319—Methods of introducing gases into liquid media
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B13/00—Oxygen; Ozone; Oxides or hydroxides in general
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B13/00—Oxygen; Ozone; Oxides or hydroxides in general
    • C01B13/02—Preparation of oxygen
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B5/00—Water
    • D—TEXTILES; PAPER
    • D21—PAPER-MAKING; PRODUCTION OF CELLULOSE
    • D21C—PRODUCTION OF CELLULOSE BY REMOVING NON-CELLULOSE SUBSTANCES FROM CELLULOSE-CONTAINING MATERIALS; REGENERATION OF PULPING LIQUORS; APPARATUS THEREFOR
    • D21C9/00—After-treatment of cellulose pulp, e.g. of wood pulp, or cotton linters ; Treatment of dilute or dewatered pulp or process improvement taking place after obtaining the raw cellulosic material and not provided for elsewhere
    • D21C9/10—Bleaching ; Apparatus therefor
    • D21C9/147—Bleaching ; Apparatus therefor with oxygen or its allotropic modifications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1678—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes intracorporal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A61M2202/0476—Oxygenated solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S261/00—Gas and liquid contact apparatus
    • Y10S261/28—Blood oxygenators

Abstract

An apparatus (10) and method for delivering a high partial pressure of a gas into a liquid. The apparatus includes a gas transfer device (12) with includes a housing (14) having upstream (16) and downstream (18) regions, between which there is located a gas-liquid contacting region (20) with contacting members (22) such as hollow microporous fibers. A reservoir (36) of gas supplied gas at a high pressure (P) to a flask (38) containing gas-depleted liquid and to the gas transfer device (12). The reservoir (36) of gas provides hydrostatic pressure for urging the liquid through the contacting members (22) and propelling the gas around the contacting members (32) so that the gas does not diffuse across the contacting members. The gas-enriched liquid is then conducted to a high resistance delivery channel (44) for administration to a site of interest with effervescence, bubble formation or significant disruption of laminar flow.
PCT/US1996/008424 1995-06-07 1996-06-03 High pressure gas exchanger WO1996041987A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU59702/96A AU5970296A (en) 1995-06-07 1996-06-03 High pressure gas exchanger
JP50310897A JP3848370B2 (en) 1995-06-07 1996-06-03 High pressure gas converter
DE69630223T DE69630223T2 (en) 1995-06-07 1996-06-03 HIGH PRESSURE GAS EXCHANGE.
EP96916998A EP0838010B1 (en) 1995-06-07 1996-06-03 High pressure gas exchanger

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/484,284 US5730935A (en) 1984-07-12 1995-06-07 High pressure gas exchanger
US08/484,284 1995-06-07

Publications (2)

Publication Number Publication Date
WO1996041987A2 WO1996041987A2 (en) 1996-12-27
WO1996041987A3 true WO1996041987A3 (en) 1997-02-27

Family

ID=23923511

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/008424 WO1996041987A2 (en) 1995-06-07 1996-06-03 High pressure gas exchanger

Country Status (7)

Country Link
US (1) US5730935A (en)
EP (1) EP0838010B1 (en)
JP (1) JP3848370B2 (en)
AU (1) AU5970296A (en)
CA (1) CA2224101A1 (en)
DE (1) DE69630223T2 (en)
WO (1) WO1996041987A2 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6315942B1 (en) * 1993-11-15 2001-11-13 Wayne State University System for delivery of gas-enriched fluids
US6676900B1 (en) 1994-12-09 2004-01-13 Therox, Inc. Method for the preparation and delivery of gas-enriched fluids
US6312647B1 (en) 1994-12-09 2001-11-06 Wayne State University Method for enriching a fluid with oxygen
US6607698B1 (en) * 1997-08-15 2003-08-19 Therox, Inc. Method for generalized extracorporeal support
US6394096B1 (en) 1998-07-15 2002-05-28 Corazon Technologies, Inc. Method and apparatus for treatment of cardiovascular tissue mineralization
US6527979B2 (en) * 1999-08-27 2003-03-04 Corazon Technologies, Inc. Catheter systems and methods for their use in the treatment of calcified vascular occlusions
US6602467B1 (en) 1998-07-24 2003-08-05 Therox, Inc. Apparatus and method for blood oxygenation
US6576191B1 (en) 1999-09-30 2003-06-10 Therox, Inc. Apparatus for blood oxygenation
ATE450279T1 (en) * 1999-09-30 2009-12-15 Therox Inc DEVICE AND METHOD FOR SUPERSATURATING A LIQUID WITH GAS
US6759008B1 (en) 1999-09-30 2004-07-06 Therox, Inc. Apparatus and method for blood oxygenation
US6890482B2 (en) 1999-09-30 2005-05-10 Therox, Inc. Apparatus for blood oxygenation
US6387324B1 (en) * 1999-09-30 2002-05-14 Therox, Inc. Apparatus and method for blood oxygenation
US7008535B1 (en) * 2000-08-04 2006-03-07 Wayne State University Apparatus for oxygenating wastewater
US6613280B2 (en) * 2001-03-20 2003-09-02 Therox, Inc. Disposable cartridge for producing gas-enriched fluids
US6582387B2 (en) 2001-03-20 2003-06-24 Therox, Inc. System for enriching a bodily fluid with a gas
US20030051742A1 (en) * 2001-04-19 2003-03-20 Boyers David G. Method and apparatus for treating a substrate with an ozone-solvent solution II
US8636952B2 (en) 2008-12-04 2014-01-28 Therox, Inc. System for enriching a bodily fluid with a gas having a removable gas-enrichment device with an information recording element
US8246564B2 (en) 2008-12-04 2012-08-21 Therox, Inc. System for enriching a bodily fluid with a gas having automated priming capabilities
US8192384B2 (en) 2008-12-04 2012-06-05 Therox, Inc. System for enriching a bodily fluid with a gas having a dual-function power switch mechanism
US10961488B2 (en) * 2015-04-15 2021-03-30 Board Of Trustees Of The University Of Arkansas Method for controlling the concentration of single and multiple dissolved gases in beverages
DE102021129141A1 (en) 2021-11-09 2023-05-11 Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Körperschaft des öffentlichen Rechts Enrichment of fluids under pressure with enrichment gas

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US4493692A (en) * 1982-09-29 1985-01-15 Reed Charles C Blood gas concentration control apparatus and method
US4602987A (en) * 1984-09-24 1986-07-29 Aquanautics Corporation System for the extraction and utilization of oxygen from fluids
US4686085A (en) * 1980-04-14 1987-08-11 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4919895A (en) * 1986-09-23 1990-04-24 Alpha Therapeutic Corporation Apparatus for oxygenation of liquid state dissolved oxygen-carrying formulation
US4968483A (en) * 1987-01-15 1990-11-06 Quarzlampenfabrik Dr.-Ing. Felix W. Muller Gmbh & Co. Kg Apparatus for the production of oxygenated blood
US5084011A (en) * 1990-01-25 1992-01-28 Grady Daniel J Method for oxygen therapy using hyperbarically oxygenated liquid
US5366696A (en) * 1993-01-07 1994-11-22 1077075 Ontario Inc. Oxygenation apparatus for oxygenating a carrier liquid by spraying

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2649126A1 (en) * 1976-10-28 1978-05-03 Linde Ag METHOD AND DEVICE FOR FUMING A LIQUID
US4686085A (en) * 1980-04-14 1987-08-11 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4493692A (en) * 1982-09-29 1985-01-15 Reed Charles C Blood gas concentration control apparatus and method
US4602987A (en) * 1984-09-24 1986-07-29 Aquanautics Corporation System for the extraction and utilization of oxygen from fluids
US4919895A (en) * 1986-09-23 1990-04-24 Alpha Therapeutic Corporation Apparatus for oxygenation of liquid state dissolved oxygen-carrying formulation
US4968483A (en) * 1987-01-15 1990-11-06 Quarzlampenfabrik Dr.-Ing. Felix W. Muller Gmbh & Co. Kg Apparatus for the production of oxygenated blood
US5084011A (en) * 1990-01-25 1992-01-28 Grady Daniel J Method for oxygen therapy using hyperbarically oxygenated liquid
US5366696A (en) * 1993-01-07 1994-11-22 1077075 Ontario Inc. Oxygenation apparatus for oxygenating a carrier liquid by spraying

Also Published As

Publication number Publication date
AU5970296A (en) 1997-01-09
JP3848370B2 (en) 2006-11-22
JPH11507869A (en) 1999-07-13
US5730935A (en) 1998-03-24
EP0838010B1 (en) 2003-10-01
DE69630223D1 (en) 2003-11-06
DE69630223T2 (en) 2004-08-05
CA2224101A1 (en) 1996-12-27
WO1996041987A2 (en) 1996-12-27
EP0838010A4 (en) 1999-06-09
EP0838010A2 (en) 1998-04-29

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