WO1997040383A1 - Systems and methods for arraying beads - Google Patents
Systems and methods for arraying beads Download PDFInfo
- Publication number
- WO1997040383A1 WO1997040383A1 PCT/EP1997/002039 EP9702039W WO9740383A1 WO 1997040383 A1 WO1997040383 A1 WO 1997040383A1 EP 9702039 W EP9702039 W EP 9702039W WO 9740383 A1 WO9740383 A1 WO 9740383A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- solid supports
- receiving region
- selected areas
- solid
- plate
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/00459—Beads
- B01J2219/00466—Beads in a slurry
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/00459—Beads
- B01J2219/00468—Beads by manipulation of individual beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
- B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU27677/97A AU2767797A (en) | 1996-04-24 | 1997-04-23 | Systems and methods for arraying beads |
EP97921699A EP0900378A1 (en) | 1996-04-24 | 1997-04-23 | Systems and methods for arraying beads |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63712396A | 1996-04-24 | 1996-04-24 | |
US08/637,123 | 1996-04-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997040383A1 true WO1997040383A1 (en) | 1997-10-30 |
Family
ID=24554636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1997/002039 WO1997040383A1 (en) | 1996-04-24 | 1997-04-23 | Systems and methods for arraying beads |
Country Status (4)
Country | Link |
---|---|
US (1) | US6074609A (en) |
EP (1) | EP0900378A1 (en) |
AU (1) | AU2767797A (en) |
WO (1) | WO1997040383A1 (en) |
Cited By (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998046549A1 (en) * | 1997-04-17 | 1998-10-22 | Zeneca Limited | Method for the preparation of a chemical library |
EP0905515A2 (en) * | 1997-09-25 | 1999-03-31 | Basf Aktiengesellschaft | Analytical measuring method and its use |
EP0955084A1 (en) * | 1998-04-27 | 1999-11-10 | Corning Incorporated | Redrawn capillary imaging reservoir |
WO1999056877A1 (en) * | 1998-04-30 | 1999-11-11 | Graffinity Pharmaceutical Design Gmbh | Support plate for receiving a plurality of sample particles in an ordered manner |
GB2337269A (en) * | 1997-04-17 | 1999-11-17 | Zeneca Ltd | Method for the preparation of a chemical library |
WO1999060373A1 (en) * | 1998-05-20 | 1999-11-25 | Nanomont Gesellschaft Für Nanotechnologie Mbh | Method and device for fixing micro- and/or nano-objects |
WO2000027520A1 (en) * | 1998-10-27 | 2000-05-18 | Institut für Physikalische Hochtechnologie e.V. | Sample sorting, conveying and receiving device for microspheres and method for operating the same |
EP1007966A1 (en) * | 1996-08-21 | 2000-06-14 | Smithkline Beecham Corporation | Rapid process for arraying and synthesizing bead-based combinatorial libraries |
WO2000036417A1 (en) * | 1998-12-17 | 2000-06-22 | Smithkline Beecham Corporation | Apparatus and process for arraying beads |
WO2000044490A1 (en) * | 1999-01-29 | 2000-08-03 | Glaxo Group Limited | Bead picking apparatus and method |
EP1024893A4 (en) * | 1997-01-17 | 2000-08-09 | Smithkline Beecham Corp | Apparatus and process for arraying beads |
WO2000049382A2 (en) * | 1999-02-16 | 2000-08-24 | The Perkin-Elmer Corporation | Bead dispensing system |
WO2000058735A2 (en) * | 1999-03-31 | 2000-10-05 | Optigon Technologies | High throughput screening apparatus and methods for arraying microparticles |
WO2001016004A1 (en) * | 1999-09-01 | 2001-03-08 | Graffinity Pharmaceutical Design Gmbh | Method and device for picking and placing objects |
WO2001076755A1 (en) * | 2000-04-11 | 2001-10-18 | Haim Kedar | System and method for single or multiple bead distribution with an adjustable capillary |
US6347650B1 (en) | 2000-06-16 | 2002-02-19 | Discovery Partners International, Inc. | Device and method for dispensing particulate material |
US6350618B1 (en) | 1998-04-27 | 2002-02-26 | Corning Incorporated | Redrawn capillary imaging reservoir |
US6387707B1 (en) | 1996-04-25 | 2002-05-14 | Bioarray Solutions | Array Cytometry |
US6432719B1 (en) | 1999-02-16 | 2002-08-13 | Pe Corporation (Ny) | Matrix storage and dispensing system |
US6468811B1 (en) | 1996-04-25 | 2002-10-22 | Bioarray Solutions | Light-controlled electrokinetic assembly of particles near surfaces |
EP1287883A2 (en) * | 2001-08-29 | 2003-03-05 | Eastman Kodak Company | Coating composition and random array of microspheres |
WO2004024329A1 (en) * | 2002-09-13 | 2004-03-25 | Exelixis, Inc. | Apparatus for pipetting powder |
US6762061B1 (en) | 1998-07-03 | 2004-07-13 | Corning Incorporated | Redrawn capillary imaging reservoir |
US6902702B1 (en) * | 2000-08-16 | 2005-06-07 | University Health Network | Devices and methods for producing microarrays of biological samples |
US7041510B2 (en) | 1996-04-25 | 2006-05-09 | Bioarray Solutions Ltd. | System and method for programmable illumination pattern generation |
US7083914B2 (en) | 1997-05-23 | 2006-08-01 | Bioarray Solutions Ltd. | Color-encoding and in-situ interrogation of matrix-coupled chemical compounds |
US7101510B2 (en) | 1999-02-16 | 2006-09-05 | Applera Corporation | Matrix storage and dispensing system |
US7291504B2 (en) | 1996-04-25 | 2007-11-06 | Bioarray Solutions Ltd. | Assay involving detection and identification with encoded particles |
USRE43097E1 (en) | 1994-10-13 | 2012-01-10 | Illumina, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
US8691754B2 (en) | 2003-09-22 | 2014-04-08 | Bioarray Solutions, Ltd. | Microparticles with enhanced covalent binding capacity and their uses |
US9147037B2 (en) | 2004-08-02 | 2015-09-29 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
US9222886B2 (en) | 2010-12-27 | 2015-12-29 | Abbott Molecular Inc. | Quantitating high titer samples by digital PCR |
US9222115B2 (en) | 2011-12-30 | 2015-12-29 | Abbott Molecular, Inc. | Channels with cross-sectional thermal gradients |
US9251583B2 (en) | 2002-11-15 | 2016-02-02 | Bioarray Solutions, Ltd. | Analysis, secure access to, and transmission of array images |
US9273354B2 (en) | 1997-05-23 | 2016-03-01 | Illumina, Inc. | System and apparatus for sequential processing of analytes |
US9377388B2 (en) | 1997-03-14 | 2016-06-28 | Trustees Of Tufts College | Methods for detecting target analytes and enzymatic reactions |
US9436088B2 (en) | 2001-06-21 | 2016-09-06 | Bioarray Solutions, Ltd. | Un-supported polymeric film with embedded microbeads |
US9637777B2 (en) | 2003-10-28 | 2017-05-02 | Bioarray Solutions, Ltd. | Optimization of gene expression analysis using immobilized capture probes |
US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
US10107804B2 (en) | 2001-03-23 | 2018-10-23 | Trustees Of Tufts College | Methods for detecting target analytes and enzymatic reactions |
US10415081B2 (en) | 2001-10-15 | 2019-09-17 | Bioarray Solutions Ltd. | Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6969488B2 (en) * | 1998-05-22 | 2005-11-29 | Solexa, Inc. | System and apparatus for sequential processing of analytes |
US6551557B1 (en) * | 1998-07-07 | 2003-04-22 | Cartesian Technologies, Inc. | Tip design and random access array for microfluidic transfer |
US6497155B1 (en) | 1999-02-09 | 2002-12-24 | Pharmacopeia, Inc. | Article comprising a particle retrieval device |
US20020182749A1 (en) * | 1999-05-11 | 2002-12-05 | Aclara Biosciences, Inc. | Sample evaporative control |
US7185476B1 (en) * | 1999-05-11 | 2007-03-06 | Mts, Medication Technologies, Inc. | Automated solid pharmaceutical product packaging machine |
US6858185B1 (en) * | 1999-08-25 | 2005-02-22 | Caliper Life Sciences, Inc. | Dilutions in high throughput systems with a single vacuum source |
US6338825B1 (en) * | 1999-08-30 | 2002-01-15 | Jay Skeen | Pipette tip having plural channels and a titration kit therefor |
US6645431B2 (en) * | 2001-01-22 | 2003-11-11 | Thomas W. Astle | Apparatus for automated magnetic separation of materials in laboratory trays |
CA2464682A1 (en) * | 2001-10-26 | 2003-05-01 | Sequenom, Inc. | Method and apparatus for high-throughput sample handling process line |
US6838289B2 (en) * | 2001-11-14 | 2005-01-04 | Beckman Coulter, Inc. | Analyte detection system |
US20040038303A1 (en) * | 2002-04-08 | 2004-02-26 | Unger Gretchen M. | Biologic modulations with nanoparticles |
EP1540344A4 (en) * | 2002-08-02 | 2007-02-21 | Applera Corp | Fluorescence polarization assay |
US20040129676A1 (en) * | 2003-01-07 | 2004-07-08 | Tan Roy H. | Apparatus for transfer of an array of liquids and methods for manufacturing same |
US7442339B2 (en) * | 2004-03-31 | 2008-10-28 | Intel Corporation | Microfluidic apparatus, Raman spectroscopy systems, and methods for performing molecular reactions |
US8211386B2 (en) | 2004-06-08 | 2012-07-03 | Biokit, S.A. | Tapered cuvette and method of collecting magnetic particles |
DE102005025640A1 (en) * | 2005-06-03 | 2006-12-07 | Scienion Ag | Microdispenser and associated operating method |
US20070043510A1 (en) * | 2005-08-19 | 2007-02-22 | Beckman Coulter, Inc. | Assay system |
DE102006029032A1 (en) * | 2006-02-17 | 2007-08-23 | Poly-An Gesellschaft zur Herstellung von Polymeren für spezielle Anwendungen und Analytik mbH | Apparatus, method and kit for detecting analytes in a sample |
DE502007005242D1 (en) * | 2006-02-24 | 2010-11-18 | Roche Diagnostics Gmbh | Plate for distributing bullets |
WO2007130434A2 (en) * | 2006-05-02 | 2007-11-15 | Applera Corporation | Variable volume dispenser and method |
US20100190654A1 (en) * | 2006-12-05 | 2010-07-29 | Liquidia Technologies , Inc. | Nanoarrays and methods and materials for fabricating same |
US8028591B2 (en) * | 2007-05-11 | 2011-10-04 | Applied Biosystems Llc | System and method for selective retrieval of support beads |
US8858899B2 (en) * | 2009-06-10 | 2014-10-14 | Ge Healthcare Bio-Sciences Ab | Fraction collector |
USD666099S1 (en) | 2010-11-01 | 2012-08-28 | Colgate-Palmolive Company | Cap for a container |
USD666096S1 (en) | 2010-11-01 | 2012-08-28 | Colgate-Palmolive Company | Cap for a container |
USD666097S1 (en) | 2010-11-01 | 2012-08-28 | Colgate-Palmolive Company | Cap for a container |
USD666493S1 (en) | 2010-11-01 | 2012-09-04 | Colgate-Palmolive Company | Cap for a container |
USD666098S1 (en) | 2010-11-01 | 2012-08-28 | Colgate-Palmolive Company | Cap for a container |
USD666492S1 (en) | 2010-11-01 | 2012-09-04 | Colgate-Palmolive Company | Cap for a container |
WO2012154552A1 (en) * | 2011-05-06 | 2012-11-15 | Phylonix Pharmaceuticals, Inc. | Method and device for removing particles from liquid and placing them into a holding device |
WO2013140128A1 (en) | 2012-03-21 | 2013-09-26 | Dynex Technologies, Inc. | Reagent bead inserter |
SG10201902499VA (en) | 2014-09-03 | 2019-04-29 | Genesegues Inc | Therapeutic nanoparticles and related compositions, methods and systems |
WO2020016552A1 (en) | 2018-07-19 | 2020-01-23 | Dynex Technologies, Inc. | Multiplexed sample plate |
WO2023009699A1 (en) * | 2021-07-29 | 2023-02-02 | Gen-Probe Incorporated | Automated systems and methods for loading solid reagent pellets into wells of a cartridge |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3932141A (en) * | 1974-07-10 | 1976-01-13 | Abbott Laboratories | Apparatus for determining immunoassays of antigens and their antibodies |
US4101284A (en) * | 1977-10-25 | 1978-07-18 | Abbott Laboratories | Multiple bead dispenser for diagnostic assay |
US4649116A (en) * | 1983-10-27 | 1987-03-10 | Institut Pasteur | Magnetic means for withdrawing magnetic gel beads from an assay fluid |
JPS6480862A (en) * | 1987-09-24 | 1989-03-27 | Toyo Boseki | Method for moving spherical carrier for antigen-antibody reaction |
US4837159A (en) * | 1984-09-21 | 1989-06-06 | Olympus Optical Co., Ltd. | Method and apparatus for effecting immunological analysis |
US5382512A (en) * | 1993-08-23 | 1995-01-17 | Chiron Corporation | Assay device with captured particle reagent |
DE4329791A1 (en) * | 1993-09-03 | 1995-03-30 | Teja Lichtenberg | Method and device for automatic distribution of microfilter discs |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3568735A (en) * | 1968-06-26 | 1971-03-09 | Cooke Eng Co | Laboratory microtitration dispensing apparatus |
BE759942A (en) * | 1969-12-08 | 1971-05-17 | Morgan Construction Co | DEVICE FOR TRANSFERRING COILS OF CYLINDRICAL PRODUCT FROM A COIL FORMING STATION TO AN ADJACENT CONVEYOR |
US3940172A (en) * | 1974-04-22 | 1976-02-24 | Clifford L. Hutson | Vacuum-actuated pick-up instrument |
US4266905A (en) * | 1979-04-20 | 1981-05-12 | Board Of Regents For Education Of The State Of Rhode Island | Apparatus for acquiring workpieces from a storage bin or the like |
US4937048A (en) * | 1983-01-31 | 1990-06-26 | Olympus Optical Company Limited | Carrier transporting apparatus and carrier container for use in an immunological analysis |
US4768919A (en) * | 1984-01-12 | 1988-09-06 | Sunkist Growers, Inc. | Vacuum apparatus for transferring round food articles |
DE3611789A1 (en) * | 1986-04-08 | 1987-10-22 | Sedlbauer Wilhelm Gmbh | HOLDING DEVICE FOR RECEIVING, TRANSPORTING AND DEPOSITING SMALL COMPONENTS |
JP2662215B2 (en) * | 1986-11-19 | 1997-10-08 | 株式会社日立製作所 | Cell holding device |
JPH01281231A (en) * | 1987-10-22 | 1989-11-13 | Fujitsu Ltd | Testpiece holding device |
FR2624778B1 (en) * | 1987-12-22 | 1994-09-23 | Recif Sa | NOZZLE FOR VACUUM PIPETTE |
US4887351A (en) * | 1988-09-09 | 1989-12-19 | Universal Instruments Corporation | Pick and place nozzle with concentric grooves |
US5185269A (en) * | 1990-02-13 | 1993-02-09 | Source Scientific Systems, Inc. | Immunobead aspirator and method of use |
US5207467A (en) * | 1990-08-31 | 1993-05-04 | International Business Machines Corporation | Monitor for detecting the absence of an electronic component on a vacuum pickup |
US5171537A (en) * | 1991-05-06 | 1992-12-15 | Richard E. MacDonald | Activated immunodiagnostic pipette tips |
US5280979A (en) * | 1991-06-20 | 1994-01-25 | Recif, S.A. | Tip for a vacuum pipette with improved electrostatic discharge properties |
CA2132270A1 (en) * | 1993-10-28 | 1995-04-29 | Erich Lerch | Automatic pipetting apparatus having a cleaning device |
JP3115501B2 (en) * | 1994-06-15 | 2000-12-11 | プレシジョン・システム・サイエンス株式会社 | Method for controlling desorption of magnetic material using dispenser and various devices processed by this method |
US5414955A (en) * | 1994-08-03 | 1995-05-16 | Morin; Thomas M. | Hand held seeder |
US5567326A (en) * | 1994-09-19 | 1996-10-22 | Promega Corporation | Multisample magnetic separation device |
WO1998032000A1 (en) * | 1997-01-17 | 1998-07-23 | Smithkline Beecham Corporation | Apparatus and process for arraying beads |
-
1997
- 1997-04-03 US US08/834,803 patent/US6074609A/en not_active Expired - Fee Related
- 1997-04-23 WO PCT/EP1997/002039 patent/WO1997040383A1/en not_active Application Discontinuation
- 1997-04-23 AU AU27677/97A patent/AU2767797A/en not_active Abandoned
- 1997-04-23 EP EP97921699A patent/EP0900378A1/en not_active Withdrawn
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3932141A (en) * | 1974-07-10 | 1976-01-13 | Abbott Laboratories | Apparatus for determining immunoassays of antigens and their antibodies |
US4101284A (en) * | 1977-10-25 | 1978-07-18 | Abbott Laboratories | Multiple bead dispenser for diagnostic assay |
US4649116A (en) * | 1983-10-27 | 1987-03-10 | Institut Pasteur | Magnetic means for withdrawing magnetic gel beads from an assay fluid |
US4837159A (en) * | 1984-09-21 | 1989-06-06 | Olympus Optical Co., Ltd. | Method and apparatus for effecting immunological analysis |
JPS6480862A (en) * | 1987-09-24 | 1989-03-27 | Toyo Boseki | Method for moving spherical carrier for antigen-antibody reaction |
US5382512A (en) * | 1993-08-23 | 1995-01-17 | Chiron Corporation | Assay device with captured particle reagent |
DE4329791A1 (en) * | 1993-09-03 | 1995-03-30 | Teja Lichtenberg | Method and device for automatic distribution of microfilter discs |
Non-Patent Citations (2)
Title |
---|
DATABASE WPI Section Ch Week 8918, Derwent World Patents Index; Class B04, AN 89-134927 * |
PATENT ABSTRACTS OF JAPAN vol. 13, no. 306 (P - 897) 13 July 1989 (1989-07-13) * |
Cited By (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE43097E1 (en) | 1994-10-13 | 2012-01-10 | Illumina, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
US8691594B2 (en) | 1996-04-25 | 2014-04-08 | Bioarray Solutions, Ltd. | Method of making a microbead array with attached biomolecules |
US6387707B1 (en) | 1996-04-25 | 2002-05-14 | Bioarray Solutions | Array Cytometry |
US6797524B1 (en) | 1996-04-25 | 2004-09-28 | Bioarray Solutions Ltd. | Light-controlled electrokinetic assembly of particles near surfaces |
US7615345B2 (en) | 1996-04-25 | 2009-11-10 | Bio Array Solutions Ltd. | Arrays formed of encoded beads having oligonucleotides attached |
US7291504B2 (en) | 1996-04-25 | 2007-11-06 | Bioarray Solutions Ltd. | Assay involving detection and identification with encoded particles |
US9400259B2 (en) | 1996-04-25 | 2016-07-26 | Bioarray Solutions, Ltd. | Method of making a microbead array with attached biomolecules |
US6514771B1 (en) | 1996-04-25 | 2003-02-04 | Bioarray Solutions | Light-controlled electrokinetic assembly of particles near surfaces |
US7041510B2 (en) | 1996-04-25 | 2006-05-09 | Bioarray Solutions Ltd. | System and method for programmable illumination pattern generation |
US6468811B1 (en) | 1996-04-25 | 2002-10-22 | Bioarray Solutions | Light-controlled electrokinetic assembly of particles near surfaces |
EP1007966A1 (en) * | 1996-08-21 | 2000-06-14 | Smithkline Beecham Corporation | Rapid process for arraying and synthesizing bead-based combinatorial libraries |
US6376256B1 (en) | 1996-08-21 | 2002-04-23 | Smithkline Beecham Corporation | Rapid process for arraying and synthesizing bead-based combinatorial libraries |
EP1007966A4 (en) * | 1996-08-21 | 2001-10-17 | Smithkline Beecham Corp | Rapid process for arraying and synthesizing bead-based combinatorial libraries |
EP1024893A4 (en) * | 1997-01-17 | 2000-08-09 | Smithkline Beecham Corp | Apparatus and process for arraying beads |
EP1024893A1 (en) * | 1997-01-17 | 2000-08-09 | Smithkline Beecham Corporation | Apparatus and process for arraying beads |
US9377388B2 (en) | 1997-03-14 | 2016-06-28 | Trustees Of Tufts College | Methods for detecting target analytes and enzymatic reactions |
US10241026B2 (en) | 1997-03-14 | 2019-03-26 | Trustees Of Tufts College | Target analyte sensors utilizing microspheres |
GB2337269A (en) * | 1997-04-17 | 1999-11-17 | Zeneca Ltd | Method for the preparation of a chemical library |
WO1998046549A1 (en) * | 1997-04-17 | 1998-10-22 | Zeneca Limited | Method for the preparation of a chemical library |
GB2337269B (en) * | 1997-04-17 | 2002-10-09 | Zeneca Ltd | Method for the preparation of a chemical library |
US9945051B2 (en) | 1997-05-23 | 2018-04-17 | Rutgers, The State University Of New Jersey | Color-encoding and in-situ interrogation of matrix-coupled chemical compounds |
US7083914B2 (en) | 1997-05-23 | 2006-08-01 | Bioarray Solutions Ltd. | Color-encoding and in-situ interrogation of matrix-coupled chemical compounds |
US9273354B2 (en) | 1997-05-23 | 2016-03-01 | Illumina, Inc. | System and apparatus for sequential processing of analytes |
EP0905515A2 (en) * | 1997-09-25 | 1999-03-31 | Basf Aktiengesellschaft | Analytical measuring method and its use |
EP0905515A3 (en) * | 1997-09-25 | 2000-02-23 | Basf Aktiengesellschaft | Analytical measuring method and its use |
EP0955084A1 (en) * | 1998-04-27 | 1999-11-10 | Corning Incorporated | Redrawn capillary imaging reservoir |
EP1075327A1 (en) * | 1998-04-27 | 2001-02-14 | Corning Incorporated | Redrawn capillary imaging reservoir |
EP1075327A4 (en) * | 1998-04-27 | 2006-01-25 | Corning Inc | Redrawn capillary imaging reservoir |
US6596237B1 (en) | 1998-04-27 | 2003-07-22 | Nicholas F. Borrelli | Redrawn capillary imaging reservoir |
US6350618B1 (en) | 1998-04-27 | 2002-02-26 | Corning Incorporated | Redrawn capillary imaging reservoir |
WO1999056877A1 (en) * | 1998-04-30 | 1999-11-11 | Graffinity Pharmaceutical Design Gmbh | Support plate for receiving a plurality of sample particles in an ordered manner |
WO1999060373A1 (en) * | 1998-05-20 | 1999-11-25 | Nanomont Gesellschaft Für Nanotechnologie Mbh | Method and device for fixing micro- and/or nano-objects |
US6762061B1 (en) | 1998-07-03 | 2004-07-13 | Corning Incorporated | Redrawn capillary imaging reservoir |
WO2000027520A1 (en) * | 1998-10-27 | 2000-05-18 | Institut für Physikalische Hochtechnologie e.V. | Sample sorting, conveying and receiving device for microspheres and method for operating the same |
US6255116B1 (en) * | 1998-12-17 | 2001-07-03 | Smithkline Beecham Corporation | Apparatus and process for arraying beads |
WO2000036417A1 (en) * | 1998-12-17 | 2000-06-22 | Smithkline Beecham Corporation | Apparatus and process for arraying beads |
WO2000044490A1 (en) * | 1999-01-29 | 2000-08-03 | Glaxo Group Limited | Bead picking apparatus and method |
US7615193B2 (en) | 1999-02-16 | 2009-11-10 | Applied Biosystems, Llc | Bead dispensing system |
US6887431B1 (en) | 1999-02-16 | 2005-05-03 | Applera Corporation | Bead dispensing system |
US6432719B1 (en) | 1999-02-16 | 2002-08-13 | Pe Corporation (Ny) | Matrix storage and dispensing system |
WO2000049382A2 (en) * | 1999-02-16 | 2000-08-24 | The Perkin-Elmer Corporation | Bead dispensing system |
US7384606B2 (en) | 1999-02-16 | 2008-06-10 | Applera Corporation | Bead dispensing system |
US7361309B2 (en) | 1999-02-16 | 2008-04-22 | Applera Corporation | Matrix storage and dispensing system |
WO2000049382A3 (en) * | 1999-02-16 | 2001-01-18 | Perkin Elmer Corp | Bead dispensing system |
US7101510B2 (en) | 1999-02-16 | 2006-09-05 | Applera Corporation | Matrix storage and dispensing system |
AU762897B2 (en) * | 1999-02-16 | 2003-07-10 | Applera Corporation | Bead dispensing system |
US7347975B2 (en) | 1999-02-16 | 2008-03-25 | Applera Corporation | Bead dispensing system |
WO2000058735A3 (en) * | 1999-03-31 | 2001-05-31 | Optigon Technologies | High throughput screening apparatus and methods for arraying microparticles |
WO2000058735A2 (en) * | 1999-03-31 | 2000-10-05 | Optigon Technologies | High throughput screening apparatus and methods for arraying microparticles |
US6695369B2 (en) | 1999-09-01 | 2004-02-24 | Graffinity Pharmaceuticals Ag | Device and method for picking up and placing objects |
WO2001016004A1 (en) * | 1999-09-01 | 2001-03-08 | Graffinity Pharmaceutical Design Gmbh | Method and device for picking and placing objects |
WO2001076755A1 (en) * | 2000-04-11 | 2001-10-18 | Haim Kedar | System and method for single or multiple bead distribution with an adjustable capillary |
US6471917B1 (en) | 2000-04-11 | 2002-10-29 | Affymax, Inc. | System and method for single or multiple bead distribution with an adjustable capillary |
US6347650B1 (en) | 2000-06-16 | 2002-02-19 | Discovery Partners International, Inc. | Device and method for dispensing particulate material |
US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
US6902702B1 (en) * | 2000-08-16 | 2005-06-07 | University Health Network | Devices and methods for producing microarrays of biological samples |
US10107804B2 (en) | 2001-03-23 | 2018-10-23 | Trustees Of Tufts College | Methods for detecting target analytes and enzymatic reactions |
US9436088B2 (en) | 2001-06-21 | 2016-09-06 | Bioarray Solutions, Ltd. | Un-supported polymeric film with embedded microbeads |
EP1287883A2 (en) * | 2001-08-29 | 2003-03-05 | Eastman Kodak Company | Coating composition and random array of microspheres |
EP1287883A3 (en) * | 2001-08-29 | 2006-05-03 | Eastman Kodak Company | Coating composition and random array of microspheres |
US10415081B2 (en) | 2001-10-15 | 2019-09-17 | Bioarray Solutions Ltd. | Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection |
WO2004024329A1 (en) * | 2002-09-13 | 2004-03-25 | Exelixis, Inc. | Apparatus for pipetting powder |
US9251583B2 (en) | 2002-11-15 | 2016-02-02 | Bioarray Solutions, Ltd. | Analysis, secure access to, and transmission of array images |
US8691754B2 (en) | 2003-09-22 | 2014-04-08 | Bioarray Solutions, Ltd. | Microparticles with enhanced covalent binding capacity and their uses |
US9637777B2 (en) | 2003-10-28 | 2017-05-02 | Bioarray Solutions, Ltd. | Optimization of gene expression analysis using immobilized capture probes |
US9147037B2 (en) | 2004-08-02 | 2015-09-29 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
EP3181704A1 (en) | 2010-12-27 | 2017-06-21 | Abbott Molecular Inc. | Quantitating high titer samples by digital pcr |
US9222886B2 (en) | 2010-12-27 | 2015-12-29 | Abbott Molecular Inc. | Quantitating high titer samples by digital PCR |
US10774376B2 (en) | 2010-12-27 | 2020-09-15 | Abbott Molecular Inc. | Quantitating high titer samples by digital PCR |
EP3839064A1 (en) | 2010-12-27 | 2021-06-23 | Abbott Molecular Inc. | Systems for quantitating high titer samples by digital pcr |
US10052632B2 (en) | 2011-12-30 | 2018-08-21 | Abbott Molecular Inc. | Channels with cross-sectional thermal gradients |
US9222115B2 (en) | 2011-12-30 | 2015-12-29 | Abbott Molecular, Inc. | Channels with cross-sectional thermal gradients |
Also Published As
Publication number | Publication date |
---|---|
EP0900378A1 (en) | 1999-03-10 |
AU2767797A (en) | 1997-11-12 |
US6074609A (en) | 2000-06-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6074609A (en) | Systems for arraying beads | |
CN101310169B (en) | Method of liquid droplet formation and transport, apparatus and particle manipulating apparatus | |
US7488451B2 (en) | Systems for particle manipulation | |
US5260028A (en) | Method and apparatus for effecting solid phase extraction | |
EP1159622B1 (en) | Apparatus and method for transferring small volumes of substances | |
US6376256B1 (en) | Rapid process for arraying and synthesizing bead-based combinatorial libraries | |
US5935859A (en) | Apparatus and process for arraying beads | |
US5979251A (en) | Apparatus and method for distributing beads | |
EP1722235B1 (en) | Device for capturing beads and method and apparatus for arraying beads | |
AU6640190A (en) | Array-type multiple cell injector | |
EP0946284A1 (en) | Method and apparatus for transferring and combining reagents | |
JP2005507492A (en) | Method for screening materials in microwell arrays | |
WO1997017258A1 (en) | Device and methods for dispensing beads | |
CA2529886A1 (en) | Apparatus and method for handling fluids for analysis | |
JP2005531006A (en) | Biochip holder and fluid recovery method | |
US6471917B1 (en) | System and method for single or multiple bead distribution with an adjustable capillary | |
US8338187B2 (en) | Methods and systems for controlling liquids in multiplex assays | |
US6403379B1 (en) | Reactor plate washing station | |
KR20040076891A (en) | System for housing/processing carrier and method for housing/processing carrier | |
EP1738173B1 (en) | Masked solid supports | |
US20070258862A1 (en) | Variable volume dispenser and method | |
US20220126285A1 (en) | Fluid delivery device and method for carrying out chemical or biological assays |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH HU IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TR TT UA UG US UZ VN YU AM AZ BY KG KZ MD RU TJ TM |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH KE LS MW SD SZ UG AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 1997921699 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
NENP | Non-entry into the national phase |
Ref country code: JP Ref document number: 97537743 Format of ref document f/p: F |
|
WWP | Wipo information: published in national office |
Ref document number: 1997921699 Country of ref document: EP |
|
NENP | Non-entry into the national phase |
Ref country code: CA |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1997921699 Country of ref document: EP |