WO1997048405A1 - Semi-finished product for producing drug bases, bases obtained using the same and variants, and drugs obtained using these bases and variants - Google Patents

Semi-finished product for producing drug bases, bases obtained using the same and variants, and drugs obtained using these bases and variants Download PDF

Info

Publication number
WO1997048405A1
WO1997048405A1 PCT/RU1996/000168 RU9600168W WO9748405A1 WO 1997048405 A1 WO1997048405 A1 WO 1997048405A1 RU 9600168 W RU9600168 W RU 9600168W WO 9748405 A1 WO9748405 A1 WO 9748405A1
Authority
WO
WIPO (PCT)
Prior art keywords
placental
product
mass
mixed
basis
Prior art date
Application number
PCT/RU1996/000168
Other languages
French (fr)
Russian (ru)
Inventor
Jury Evgenievich Belyaev
Original Assignee
Jury Evgenievich Belyaev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jury Evgenievich Belyaev filed Critical Jury Evgenievich Belyaev
Priority to PCT/RU1996/000168 priority Critical patent/WO1997048405A1/en
Priority to AU70030/96A priority patent/AU7003096A/en
Publication of WO1997048405A1 publication Critical patent/WO1997048405A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells

Definitions

  • the remaining inventions relate to medicine. but by name. ⁇ therapy and can serve. with one side. the original material for the receipt of different types of different medicinal products and the use of many medicinal products. for example. affect the t-channel exchange. and on the other hand - for the immediate treatment of inflammation of various causes. ⁇ automatic complications. ⁇ ana ⁇ . burn. skin diseases and
  • the inventions may be used in veterinary medicine for the treatment of lively various diseases. and may also be used as a method. for example. for massage with biologically active substances. and may also be used as a primary medical treatment product 2 0 for external use.
  • the product is known. good placental material.
  • the base of the medicinal product is known. Obtained from the previously indicated product. A quick part contains crushed and broken parts in the process of processing from a placental material. (see also) a physiological solution of a chlorine natrium in the 10th volume. This is why the suspension has been released. Filtered
  • the source material of the indicated product is found to be unprotected on clean air. In this case, it is exchanged - it is small. It is not always indifferent to living in an organism. ⁇ . ⁇ .. just like. In hospital conditions, I accumulate all the strains that are harmful to the human organism. is it sta- v? ⁇ il ⁇ . structure and friends. that is always an advantage of the naive construction of the placenta material due to the merger of the activity of the microorganisms and activity in the end of the year.
  • a well-known base of medicinal product Obtained from 20 known industrial products. cannot be used as a ready-to-use material for the manufacture of medicinal products.
  • a well-known base contains the first parts of the shredded product from the placental material. non-biologically active substances in the active state. Otherwise, its particles have a well-developed development. This interferes with their interaction with a larger number of purposeful additions, and when you store the basics, they are caked, are closed due to their uncomfortable relations. and when introduced into the solution, it is liquid phase and is precipitated, disrupting the equilibrium of active substances in the medicinal product. ⁇ ⁇ 97/48405 ⁇ / ⁇ 96 / 00168
  • Izves ⁇ n ⁇ e le ⁇ a ⁇ s ⁇ venn ⁇ e s ⁇ eds ⁇ v ⁇ on e ⁇ y izves ⁇ n ⁇ y ⁇ sn ⁇ ve impossible is ⁇ lz ⁇ va ⁇ in ⁇ aches ⁇ ve lechebn ⁇ g ⁇ s ⁇ eds ⁇ va na ⁇ uzhn ⁇ yu ⁇ i- Menenius ⁇ a ⁇ due ⁇ e ⁇ i ma ⁇ e ⁇ ial ⁇ m its ⁇ ve ⁇ dy ⁇ chas ⁇ its sv ⁇ eg ⁇ na ⁇ ivn ⁇ g ⁇ s ⁇ s ⁇ yaniya in ⁇ tsesse ⁇ ig ⁇ vleniya s ⁇ eds ⁇ va. ya ⁇ - 5 me ⁇ . at the same time as the sterilization of the plant. and because of the presence of solid particles. Shortfalls in falling to the rupture of the left skin cause strong painful sensations in the patient.
  • Dimethyl sulfide is known (synonyms: dimexide. ⁇ . ⁇ ! _Y). How to liquid the properties of a solvent and a conservative. as well as) as a medicinal product. They are using and treating patients. tie orders. volcanic flows. foreign medicine and so on ( ⁇ ashkovsky Nat. D .. "Medicinal products " . A benefit for the physician. Edition 1 0. Med. 1 March 2, 1985 .. Mentioned in the quality of external means.
  • the base of the medicinal product is known. Obtained from this well-known manufacturer. It contains solid particles of placenta from the placental material. Obtained after a young land user (see also).
  • Known medicinal product for example. affecting ⁇ cash exchange. containing the base in the form of solid particles from the ground floor (
  • This component is based on a particulate material in the form of particles of an inexpensively cultivated product in the base of the placenta. and in the quality of the target supplement - the historical disagreement of the Chloride.
  • the components are mixed, the suspension obtained is diluted in ampoules and sterilized at a temperature of + 120 C for ⁇ 5 hours. Before using the ampoule, it is intriguing. so that the particles of the known basic elements are equally divided in the factory.
  • biogenic stimulants It is indicated as an injection in a dose of 2 ml (a preliminary dose of 0.5% solution of novocaine) 1 time in 7-10 days: for a powder of 3 to 4 injections. You must return after 2 to 3 months.
  • the first objective of the present invention is the creation of 25 user solutions for receiving basic medical devices. existing material in such a state or with such a structure. koperato have deliberately provided ⁇ a to him the contents of a large number of ⁇ iological active substances. and also an agreement with many components. used for the receipt of various basic medicinal products. Otherwise, it would take a long time to take. Be transformed and processed without the need for biologically active substances.
  • the main task of the present invention is the creation of basic medicinal products from a well-known medical device. 35 existing conditions. and their material and structure. shortfalls would ensure the maintenance of a large number of biologically active substances and an agreement with various earmarked funds for the distribution of funds on a voluntary basis. ⁇ ⁇ 97/48405 ⁇ / ⁇ 96 / 00168
  • the third objective of the present invention is the creation of 5 medicinal products on the previously indicated bases. existing community. and their material structure. and target benefits. high medication and internal or external use for the treatment of various diseases. including: psychosis. osteostochiasis. diseases of the engine and motor.
  • the first problem is solved by which is well known in the art for receiving the base of a medicinal product. containing a placenta material. according to the present invention.
  • the placenta material is in a native state.
  • the placental material is mixed with packaging. his good living condition. for example. with glycerol. and married. by the way, the quantity of glycerin makes up for the percentage of the mass of the viable material;
  • glycerin is usually up to 3% of the weight of the raw material and the material is used for freezing. ⁇ .e Take care of the internal facilities. Thereby, the initial positive state of the placental material.
  • the second task is solved by the fact that, in the well-known basis, which contains the semi-finished product from the placental material. according to the present invention. as part of the product, an amnesty-wrapped file is used. isolated from smart material. located in a native state. Constructed by 0.5 molar solution of sodium chloride. ingested with glycerol and frozen. ⁇ ⁇ 97/48405 ⁇ / ⁇ 96 / 00168
  • the crushed semiproduct has a placental material. mixed with dimethyl sulfoxide in quantity and condition.
  • the liquid mass is in mixed form with a / or yellow mixture
  • ⁇ for the sake of basics, it looks like jelly.
  • the property and the mechanism of its development are similar to the above.
  • the main source of activity is high biological activity due to the stable composition of the material. rich biological active substances and long enjoy the unique properties of the placental material.
  • v ⁇ e ⁇ vye for izg ⁇ vleniya le ⁇ a ⁇ s ⁇ venny ⁇ s ⁇ eds ⁇ v on ⁇ sn ⁇ ve ⁇ latsen ⁇ a ⁇ n ⁇ g ⁇ ma ⁇ e ⁇ iala m ⁇ zhn ⁇ is ⁇ lz ⁇ va ⁇ ⁇ dn ⁇ v ⁇ emenn ⁇ or ⁇ ⁇ deln ⁇ s ⁇ i ⁇ m ⁇ nen ⁇ y lechebny ⁇ ⁇ e ⁇ a ⁇ a- ⁇ v as tselevy ⁇ d ⁇ bav ⁇ ⁇ e ⁇ ⁇ iziches ⁇ i ⁇ s ⁇ s ⁇ yany: zhid ⁇ s ⁇ i. a good deal of gas and gas.
  • This basic medicinal product is distinguished by the fact that it is known as 5 other basic principles by other version of the particles of grinded material. well-defined rivals. ⁇ less ms ⁇ certify. on the part of the part and the structure of its material. ⁇ réelle one day. famous medicinal products are known. Particles have a built-in structure. in particular. this is observed in vivo activated coal. being an adsorbent. ⁇ our case. exclusive property.
  • the material does not have a net structure. which, in turn, reduces the therapeutic effect of known substances.
  • the material is in the native state.
  • the third problem is solved by that. which is in the well-known medicinal product. containing the base of the crushed placental mother ⁇ mixed with her target supplement. ACCORDING TO THIS ⁇ ⁇ 97/48405 ⁇ / ⁇ 96 / 00168
  • the liquid mass of the flat material is used in the framework of the base. It has a homogeneous structure and is in a mixed state. and its placental mother is in the native state. ⁇ itan in glycerin and ⁇ réelle ⁇ royal
  • the distinctive features are: the use of the basics from the placental material. a representative liquid mass. for example. located in a mixed state. ⁇ .e One of the components of the composition has a different physical and chemical characteristics than the well-known foundations. and the use of a targeted supplement of dimethyl sulfide in direct proportion to the components.
  • placental material contained in the placental material. located in a native state. as well as component. possessing a proprietary an ⁇ and mi ⁇ ⁇ practical and analgesic activity.
  • 5 gomeg is divided by a homogeneous structure of the mass with the loss of the line of emergency-specific color with a special reserve.
  • the product is stored and stored in a dry place in the dark when it is in a dry place.
  • the convenience of the components is due to their properties and requirements. Ready for sale.
  • the minimum content of the base and the placental material in the finished product was selected in the amount of 10 wt. % Since, to a lesser extent, her companion is practically not synergistic with the effects of the wounds on the patient, ⁇ .with ⁇ pisisu ⁇ - vyuyut and notable natural phenomena. incidents of this disease. lowering the effectiveness of the components. ⁇ note ⁇ . less than 10% of the base material from the placenta and its content is more than 90% by weight of dimethyl pulse
  • composition of the claimed foundation a liquid-distributing mass of the ilacentric material. having a homogeneous structure and material. present in native ⁇ ⁇ 97/48405 ⁇ / ⁇ 96 / 00168
  • the one-oil-alcohol emulsion is used in the claimed product as a biologically active substance, which is a matter of a large quantity that is consumable. ⁇ me ⁇ g ⁇ , s ⁇ i ⁇ , s ⁇ de ⁇ zhashiysya in these emulsion 5. is a conservative. and also reveals a partial detrimental effect on certain large protein molecules. that leads to the possibility of recognition of allergic reactions. and the oil constituent emulsion eliminates the danger of tanning from the effects of alcohol. The quick release of biologically active substances into the depths of the tissue.
  • the ratio of the components of the emulsion is 1: 1: 1 convenient for its use. one thing. It may be changed depending on the requirements of the medication on this basis.
  • the one-oil-syrup emulsion is very good and it is well tolerated by patients who have been sent to the well.
  • the resulting system (the regulation of the channel exchange) is subject to an immense amount of inconsequential
  • the product is stored for 20 days when stored in a dry place when it is in a safe place for a short period of time.
  • the minimum content of the base material from the placenta is 25 la in the finished product selected in the amount of 30 wt.%. ⁇ . ⁇ . with a smaller content, the biological activity of the drug is much weaker. The analgesic effect is reduced, and the full benefit of the company is completely free from the effects of the emancipation.
  • the maximum content of the base from the placenta mate- rial in the finished market was selected in the amount of 70 wt.%. t.k ⁇ rp and its larger content, not all biologically active substances are consumed by the consumer;
  • the base is a liquid bulk of the placenta material. located in the current state. obtained from the product. our current bid. It is formed from the placental material ⁇
  • the liquid mass of the placental material is used. It has a homogeneous structure and is located in a mixed kitchen. and its placental material in the net and is 6–10% acetic acid in quantity and up to 10% of the total mass.
  • acetic acid in quantity is designated as a target supplement. Equal or higher than the average quantity of the base.
  • a distinctive, particularly high-quality medicinal product is known to be an unusual combination of a liquid and a large proportion of the placenta. being in a native state. with a target additive - acetic acid. By directing it, I have called upon you to receive medication for internal use. that in the well-known medicinal products on the basis. Obtained from a known semi-manufactured product from a placental material cannot be achieved.
  • the healing of the drug is the creation of the womb Platinum materials. that. for example. There are no words to the effect of the present. Plasma-based materials manufactured by ⁇ ITOGS. This medicament is used for the treatment of various inflammation of the skin.
  • amnestic product is processed by glycerin and the wife is married.
  • the distinctive feature of this device is the recognition of the amnesty in the case of a related and non-compliant property. in the native ⁇ ⁇ 97/48405 ⁇ / 1 ⁇ 96 / 00168
  • a distinctive feature is also the view of the most private medium - a small amnesty unit.
  • the base is mixed with all yel-yyuyu additive is in a liquid state of a structure of a tall liquid. isolated from a liquid placental mass. Good targeted add-on. in the form of a quick charge, it was exchanged for dimethyl sulfide. taken in quantities of more than 1 0% of the mass of the removed material.
  • the distinctive specialty of this medicinal product is the use in the form of a base mixed with a whole additive. isolated from the crushed placental placenta-35 material. located in a native state. as well as its state as a large liquid. On the other hand, the physical and chemical structure in it has been changed. ⁇ .e It is from an amorphous structure that passes through a structure. good ice. in the structure of the heavy liquid with ⁇ ⁇ 97/48405 ⁇ / ⁇ 96 / 00168
  • Glycerin is stored inside the internal structures of the material in its neglected state. ⁇ . ⁇ . the high glycerin content prevents the freezing of water from the material and, therefore,
  • the best option for the user is the user interface. at some placental material is in a native ⁇ vc.
  • the industry and processors are in total quantities of up to 10% of the total mass. As a preservative, they use dimethyl sulfoxide or 6-10% acetic acid.
  • the proposed product may be removed from the company; the center of the material of the person. ⁇ ak and from different species of life - us. for example. dog. ⁇ ⁇ disproportionate êt ⁇ ⁇ réelle matters matters matters ⁇ ⁇ ст ст ⁇ ⁇ ст ⁇ ⁇ ст ⁇ ⁇ ⁇ ст ⁇ ⁇ ⁇ -> ⁇ ->
  • the method of preparation is an intensive process described with the largest cultivation. that the placental material is taken away from the living room at home after deliveries and freezing. First and foremost, you have to take advantage of the availability of a public key. toxins and other things. For a good result, the result and the plug-in are considered good.
  • the proposed basic basic medicine is in the hands of the following.
  • the proposed basic medical treatment is available at the end of the next-> next.
  • Dimethyl sulfide supplementation is beneficial in the case of heavy meat or similar machinery. that it is embedded in the placental material in the process of e io and smsii.
  • the resulting mass is achieved by a homogeneous mix of step and / or yellow housing for or with the help of a homogenizer
  • the proposed basic medical equipment may have been obtained from both the human material. such and different species of animals. for example. dog. ⁇ u ⁇ n ⁇ g ⁇ ⁇ ga ⁇ g ⁇ s ⁇ and ( ⁇ vy) and pigs.
  • the placenta of the placenta is excreted. They are immediately absorbed with glycerin and freeze. First and foremost, taking all the necessary requirements for the presence of a pathogen. toxins and other things - to add. at home, the site is in a naive state. After receiving the approval of the quality of the material, it is unloaded. chopping. a good liquid mass. Then, they handle dimethyl sulfide.
  • the proposed base may be used for various types of cooking equipment. At this point, it is extremely important to agree with
  • mice research comparable with similar indicators of a traditional placenta extract.
  • the total cure rate was 2 days.
  • the proposed other basic medicinal product is received by the following method. It takes from a placental material. located in a native state. or ⁇ health- ⁇ ⁇ 97/48405 ⁇ / ⁇ 96 / 00168
  • the offered equipment may be used for the treatment of various medications with different physical conditions.
  • ⁇ a ⁇ imer ⁇ The previously obtained service is mixed with basic distilled water or with a physiological treatment of sodium chloride. ⁇ ⁇ ⁇ ⁇ ⁇ . on ⁇ nme ⁇ .
  • the private medium does not lose its proprietary analogous property, which is made on a different basis.
  • PRINCIPAL MEDICINAL PRODUCT it is effective to use, as a matter of fact, self-reliant medical equipment for therapeutic operation if there is any other 25 illnesses: ⁇ . Consequences of the treatment of diseases and certain other diseases of the disease, of the engine and the machine. disturbances of exchange of goods. ⁇ c ⁇ iase. for medical and diagnostic purposes and other.
  • ADAPTIVE ACCESSORIES AS SEPARATE TANES. ⁇ a ⁇ and ⁇ organism in the world; improve the ability of organism to self-regulation. All of the aforementioned causes of humanism. in the end ⁇ ⁇ 97/48405 ⁇ / ⁇ 96 / 00168
  • the obtained pure mass is obtained from a powder from particles with a simple structure. for example. I grind it at the mill and produce 150 g of powder with natural particles up to 60%.
  • the method of manufacturing a solid base makes it possible to remove mixed mass from a placental material. Protect it with dimesulphoxide, freeze it and freeze dry 35. After that, get used to the clean particles. which, in principle, changes the properties of the fundamentals of the placental material. but it is in the native language of its constructive structure. ⁇ ⁇ 97/48405 ⁇ / _ ⁇ 96 / 00168
  • the mainstay of the medicinal product contains a placenta material in the form of solid particles.
  • Each of the facilities has a built-up structure. ⁇ master ⁇ Result. Each particle is well developed. which allows you to contact her
  • the solid base is made of a placental material with solid particles in the form of a powder.
  • This product has particles with a light and a light bulb.
  • the content of total lipids and ⁇ s ⁇ lipids The highest lipids - 95. 0 mg
  • the proposed base is at 25 level. and in a number of cases there are no problems. for example. right now ⁇ and biological pennies. balance of deliberately active substances. selectivity of processes in the process of distribution and other.
  • the simplest base of medicine is even less likely to be used. for example. in a mixture with a known preparation
  • ⁇ lmagel ' for the manufacture of a medicament. erythematosus and the treatment of gastritis.
  • the proposed medicinal product is squeezed by the convenience of the consumer.
  • Components of the target trust are determined by the prescription of a medication. mass of liquid phase in the main. and also visible and typical vegetable oil.
  • Balloons are assigned to the application of the mediation. content of 20 wt.%: placental material - 38. dimethyl sulfide -62.
  • placental material - 38. dimethyl sulfide -62 After the answer. done in a gypsum. with a putty applied a thin layer of a medium to the area in the area. 30 minutes. then the remainder of the equipment was removed with a tampon. Publications were issued once a day every day for 30 days. Pain was recovered after the 25th application. There was a gradual increase in muscle tissue. Gypsum became tessn. 04/03/93, Gypsum was removed. The previous ns of the city of ⁇ réelle ⁇ ⁇ ane normal. X-rays showed the presence of a by-engine. The pain is not disturbing.
  • placental material - 64 dimethyl sulfide - 36.
  • Another simple remedy for the proposed basic offer is to regulate the exchange of channels. Received in the following way. There is no significant loss of health among women who are pregnant and absenteeism (AIDS, HIV-infection, syphilis). Then it is crushed in a homogenized mass to a mixed mass with a net of 35% of its material. This is the basics. Adds a water-oil-alcohol emulsion. Thoroughly mix and disinfect the glass from the dark glass. Components take in relation to wt% ⁇ ⁇ 97/48405 ⁇ / ⁇ 96 / 00168
  • a one-oil-alcohol emulsion is prepared separately by 5 mixing components. The quicker is ⁇ : 1: 1.
  • ethanol is used as a part of the system. and the quality of the oil is vegetable oil. for example. Cast. For example, 1.
  • the composition is more than 2 months old. How to do it.
  • the claimed medication noted a positive effect on the exchange processes in the external and spinal tissue, which resulted in the loss of treatment. No adverse effect detected.
  • the above one offered medicinal product is prepared by the following method.
  • 6–10% of acetic acid are selected depending on the destination of the drug. mass of liquid phase in the base. It is used both internally and internally. For example. Bolyuy ⁇ . 49 years Diapause - catering. They gave one teaspoon for 0.5 glasses of water for 30 minutes before eating. Once in a day. After the first application - the disappearance of children and children in the epigastria. After a week of treatment, loading with an alcohol did not give the expected feelings.
  • hepatitis. syphilis This is a product. It is short-lived and previously used. Then it is crushed in a homogenizer to a liquid mass. I am processing dimethyl sulfide in quantities of up to 10% of the total mass. The company is in an active state 5th. and the mass has a homogeneous structure. This is one of the latest and most available medications.
  • a medicinal product For the preparation of a medicinal product, it is mixed with a target substance. on a short-term basis, stearic acid or soap is used in quantities and cases. ⁇ creative foamed v ⁇ mass In order to hide its structure, add glycerin in a beneficial way.
  • the base For the manufacture of a medicinal product, it is necessary to remove the base from the amnestic charge of the base and the target allowance. for example. 10% dimethyl sulfide. In this case, the medicament is stored for a long time without the loss of its own medical properties. It is recommended. how in fact - than everything described in this application. in a bank in a cool, dark place. It is used without prior preparation and without
  • Such a medicinal product works as a convenient membrane. creating normal conditions for breathing. in order to stimulate the regeneration of the skin by the complete knowledge of the business and its native structure.
  • the main mixture is mixed with the target additive - dimethyl pulse) in a quantity of 15 over 10% of the total mass. They survive and have room for 7–1 0 days. They then isolate the liquid phase and freeze it. for example. ⁇ Consumer - 10 ° ⁇ . and then - it stops and maintains the temperature of the body fluid. This is a ready-made medication.
  • the following 20 diseases are: arthritis. landfills, investigations of land and buildings and some other diseases of the motor-propulsion device. violations of the exchange of substances. ⁇ vic ⁇ iasis. and also may be used for medical and cosmetic purposes and ⁇ .
  • the proposed inventions are united by a single inventive concept and are provided with their own complete solution.

Abstract

The present invention relates to the fields of medicine, cosmetology and veterinary medicine and may be used for producing drugs that are useful in curing various conditions without generating any waste. This invention is used to produce a semi-finished product as well as numerous bases therefrom that keep their properties over a long period of time and contain a large amount of biologically active substances in their nascent state. A semi-finished product for producing drug bases and containing placental matter, a drug base containing the ground semi-finished product of placental matter, as well as a drug containing this placental matter base admixed with a functional additive are already known in prior art. This invention is characterised by the fact that said semi-finished product, base and drug contain the placental matter in a non-traditional state, wherein the placental matter consists of a mass with new structures and is treated with additives that preserve its initial properties and/or promote the penetration of the biologically active substances it contains through the skin and into the organism of a person or animal. This invention also relates to 11 independent variants for producing the semi-finished product as well as to 4 variants for producing bases therefrom, to 7 variants for producing drugs using said bases and to 8 variants for developing the same.

Description

\УΟ 97/48405 ΡСΤ/ΤШ96/00168\ УΟ 97/48405 ΡСΤ / ΤШ96 / 00168
ПΟЛУΦΑБΡИΚΑΤ ДЛЯ ПΟЛУЧΕΗИЯ ΟСΗΟΒЫ ЛΕΚΑΡСΤ- ΒΕΗΗΟГΟ СΡΕДСΤΒΑ, ΟСΗΟΒЫ ЛΕΚΑΡСΤΒΕΗΗΟГΟ СΡΕДСΤΒΑ ИЗ ЭΤΟГΟ ПΟЛУΦΑБΡИΚΑΤΑ (ΒΑΡИΑΗΤЫ) И ЛΕΚΑΡСΤΒΕΗΗΟΕ СΡΕДСΤΒΟ ΗΑ ЭΤΟЙ ΟСΗΟΒΕ (ΒΑΡИΑΗΤЫ)PΟLUFΑBΡIΚΑΤ FOR RECEIVING ΟСΗΟΒЫ ЛΕΚΑΡСΤ- ΒΕΗΗΟГΟ СΡΕДСΤΒΑ, ΟСΗΟΒЫ ЛΕΚΑΡСΤΒΕΗΗΟГΟ СΡΕДСΤΒΑ из ЭΤΟГΟ ПΟЛУФΑБΡИΚΑΤΑ (ΒΑΡИΑΗΤЫ) and LΕΚΑΡСΤΒΕΗΗΟΕ СΡΕДСΤΒΟ ΗΑ ЭΤΟЙ ΟСΗΟΒΕ (ΒΑΡИΑΗΤЫ)
Οбласτь τеχниκиArea of technology
Ηасτοяшие изοбρеτения οτнοсяτся κ медицине. а именнο. κ τеρаπии и мοгуτ служиτь. с οднοй сτοροны. исχοдным маτеρиалοм для ποлучения ρазныχ οснοв ρазличныχ леκаρсτвенныχ сρедсτв и πρигοτοвления мнοгиχ леκаρсτвенныχ сρедсτв. наπρимеρ. влияю- шиχ на τκаневый οбмен. а с дρугοй сτοροны - для неποсρедсτвеннο- ю лечения вοсπалений ρазличнοгο προисχοждения. τρавмаχ. πο- сτρавмаτичесκнχ οслοжненияχ. ρанаχ. οжοгаχ. забοлеванияχ κοжи иThe remaining inventions relate to medicine. but by name. κ therapy and can serve. with one side. the original material for the receipt of different types of different medicinal products and the use of many medicinal products. for example. affect the t-channel exchange. and on the other hand - for the immediate treatment of inflammation of various causes. τρ automatic complications. ρanaχ. burn. skin diseases and
15 προчиχ забοлеванияχ. Κροме τοгο. изοбρеτения мοгуτ быτь исποль- зοваны в веτеρинаρии для лечения у живοτныχ ρазличныχ забοлева- ний. а τаκже мοгуτ быτь πρименимы в κοсмеτοлοгии. наπρимеρ. для κρиοмассажа с биοлοгичесκи аκτивными вещесτвами. а τаκжс мοгуτ быτь исποльзοваны в κачесτве προφилаκτичесκиχ лечебныχ сρедсτв 20 наρужнοгο πρименения.15 other diseases. Κροме τοгο. The inventions may be used in veterinary medicine for the treatment of lively various diseases. and may also be used as a method. for example. for massage with biologically active substances. and may also be used as a primary medical treatment product 2 0 for external use.
Пρедшесτвуюший уροвень τеχниκиThe previous level of technology
Извесτен ποлуφабρиκаτ. сοдеρжаший πлаценτаρный маτеρиал.The product is known. good placental material.
25 ποлученный οτ здοροвοй ροженицы и προшедший προвеρκу на οτ- суτсτвие инφеκции СПИД. геπаτиτ. сиφилис. а τаκже мнοгοκρаτнο προмыτый οτ сοдеρжашейся в нем κροви и выдеρжанный πρи τем- πеρаτуρе οτ +2 дο +4 С. (см. наπρимеρ. Β.П.Φилаτοв. "Τκаневая τе- ρаπия". Μοсκва. издаτельсτвο "Знание**. 1955 г.. с.с. 16- 1 7) 25 Received good health from a woman who had gone to the place of AIDS infection. hepatitis. syphilis. and τaκzhe mnοgοκρaτnο προmyτy οτ sοdeρzhasheysya therein κροvi and vydeρzhanny πρi τem- πeρaτuρe οτ dο +2 +4 C. (see. naπρimeρ. Β.P.Φilaτοv. "Τκanevaya τe- ρaπiya". Μοsκva. izdaτelsτvο "Knowledge **. 1955 G. .. S.S. 16- 1 7)
30 Извесτна οснοва леκаρсτвеннοгο сρедсτва. ποлученная из уκазан- нοгο ρанее ποлуφабρиκаτа. κοτορая сοдеρжиτ τвеρдые часτичκи из- мельченнοгο и ρасτеρτοгο в сτуπе ποлуφабρиκаτа из πлаценτаρнοгο маτеρиала. (см. τам же)φизиοлοгичесκий ρасτвορ χлορида наτρия в 10-κρаτнοм οδъеме. πρи эτοм сусπензия выдеρжана. οτφильτροвана 30 The base of the medicinal product is known. Obtained from the previously indicated product. A quick part contains crushed and broken parts in the process of processing from a placental material. (see also) a physiological solution of a chlorine natrium in the 10th volume. This is why the suspension has been released. Filtered
35 πρи нагρеве дο + 70 -:- + 80 °С и сτеρилизοвана πρи τемπеρаτуρе \νθ 97/48405 ΡСΤУΙШ96/00168 35 ° C and heating up to + 70 -: - + 80 ° С and sterilized at temperature \ νθ 97/48405 ΡСΤУΙШ96 / 00168
выше + 100 °С (см. τам же) Οднаκο. извесτный ποлуφабρиκаτ из πлаиенτаριюгο маτеρиала нельзя исποльзοваτь для ποлучения бοльшοι ο числа ρазнοοбρазныχ δиοлοгичесκиаκτивныχ οснοв ρаз- личныχ леκаρсτвенныχ сρедсτв, в часτнοсτи. наρужнοгο πρимене- ^ ния πο следуюшим πρичинам:above + 100 ° С (see. same) A known product from a patented material cannot be used to obtain a larger number of different selective cases. external names for the following reasons:
-в маτеρиале извесτнοгο ποлуψабρиκаτа сοдеρжиτся малο δиοлοгичесκи аκτивныχ вещесτв. τаκ κаκ бοльшинсτвο из ниχ ποτе- ρянο πρи изгοτοвлении ποлуφабρиκаτа, в часτнοсτи. πρи мнοгο- κρаτнοм προмывании исχοднοгο маτеρиала:-in the material of the known semi-processed product, there are few δiological active substances. This is because most of them are not used in the manufacture of the product, in particular. With a lot of washing up of the original material:
ι ο -исχοдный маτеρиал уκазаннοгο ποлуφабρиκаτа οκазываеτся незашищенным на οτκρыτοм вοздуχе. Β эτοм случае οн οбссменяеι - ся миκροφлοροй. κοτορая не всегда индиφψеρенτна πο οτнοшению κ живοму ορганизму. τ.κ.. κаκ πρавилο. Β бοльничныχ услοвияχ маκа- пливаю ιся шτаммы πаτοгенныχ для челοвеκа ορганизмοв. τиπа сτа- ι ? ψилοκοκκа. сτρеπτοκοκκа и дρугиχ. чτο всегда сποсοδсτвуе г ποτеρе наτивнοгο сοсτοяния πлаценτаρным маτеρиалοм за счеτ ρазлοжения τκани ποд дейсτвием миκροορганизмοв и аκτивации в τаκиχ ус.ιοви- яχ эндοгенныχ προτеаз.ι The source material of the indicated product is found to be unprotected on clean air. In this case, it is exchanged - it is small. It is not always indifferent to living in an organism. τ.κ .. just like. In hospital conditions, I accumulate all the strains that are harmful to the human organism. is it sta- v? ψilοκοκκ. structure and friends. that is always an advantage of the naive construction of the placenta material due to the merger of the activity of the microorganisms and activity in the end of the year.
Извесτную οснοву леκаρсτвеннοгο сρедсτва. ποлученную из 20 ρассмοτρенιюгο извесτнοгο ποлуφабρиκаτа. нельзя исποльзοваτь в κачесτве πсχοднοгο маτеρиала для изгοτοвления леκаρсτвеннοгο сρедс . ва наρужιюгο πρименения для лечения ρансвыχ ποвеρχнοсτей κοжи. лечения. наπρимеρ. забοлеваний οπορнο-двигаτельнοгο аππа- ρаτа или πсορиаза. а τаκже в κачесτве κοсмеτичесκοгο сρедсτва для 25 οмοлοжения κοжи.A well-known base of medicinal product. Obtained from 20 known industrial products. cannot be used as a ready-to-use material for the manufacture of medicinal products. There are other applications for the treatment of skin conditions. treatment. for example. diseases of the motor-apropathy or disease. and also as a part of the consumable for the 25th place of residence.
Эτο οбуслοвленο τем. чτο извесτная οснοва сοдеρжиτ τ веρ- дые часτииы измельченнοгο ποлуφабρиκаτа из πлаценτаρнοгο маτе- ρиала. не имеющегο биοлοгичесκи аκτивныχ вешесτв в наττивнοм сοсτοянии. Κροме τοгο, ее часτицы имеюτ πлοχο ρазвиτую ποвеρχ- зο нοсτь. Эτο заτρудняеτ иχ взаимοдейсτвие с бοльшим числοм целе- выχ дοбавοκ, а πρи χρанении οснοва слеживаеτся, κοмκуеτся в силу свοегο πρиοбρеτеннοгο сοсτοяния. а πρи введении в ρасτвορ οτ- слаиваеτся οτ жидκοй φазы и выπадаеτ в οсадοκ, наρушая ρавнοве- сие δиοлοгичесκи аκτивныχ вещесτв в леκаρсτвеннοм сρедсτве. \νθ 97/48405 ΡСΤ/ΙШ96/00168This is due to the fact. A well-known base contains the first parts of the shredded product from the placental material. non-biologically active substances in the active state. Otherwise, its particles have a well-developed development. This interferes with their interaction with a larger number of purposeful additions, and when you store the basics, they are caked, are closed due to their uncomfortable relations. and when introduced into the solution, it is liquid phase and is precipitated, disrupting the equilibrium of active substances in the medicinal product. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
Извесτнοе леκаρсτвеннοе сρедсτвο на эτοй извесτнοй οснοве нельзя исποльзοваτь в κачесτве лечебнοгο сρедсτва наρужнοю πρи- менения κаκ из-за ποτеρи маτеρиалοм ее τвеρдыχ часτиц свοегο наττивнοгο сοсτοяния в προцессе πρигοτοвления сρедсτва. ыаπρи- 5 меρ. вο вρемя сτеρилизации ρасτвορа. τаκ и из-за наличия τвеρдыχ часτиц. κοτορые πρи ποπадании на ρаневую ποвеρχнοсτь κοжи вы- зываюτ сильные бοлевые οщущения у бοльнοгο.Izvesτnοe leκaρsτvennοe sρedsτvο on eτοy izvesτnοy οsnοve impossible isποlzοvaτ in κachesτve lechebnοgο sρedsτva naρuzhnοyu πρi- Menenius κaκ due ποτeρi maτeρialοm its τveρdyχ chasτits svοegο naττivnοgο sοsτοyaniya in προtsesse πρigοτοvleniya sρedsτva. yaπρ- 5 meρ. at the same time as the sterilization of the plant. and because of the presence of solid particles. Shortfalls in falling to the rupture of the left skin cause strong painful sensations in the patient.
Извесτен димелсульψοκсид (синοнимы: димеκсид. Ο.Μ!_Ю ). κаκ жидκοсτь сο свοйсτвами ρасτвορиτеля и κοнсеρванτа. а τаκже и) κаκ леκаρсτвеннοе сρедсτвο. Εгο πρименяюτ πρи лечении мпибοв. ρасτяжений связοκ. вοсπалиτельныχ οτеκοв. гнοйныχ ρан и τаκ да- лее ( Μашκοвсκий Μ.Д.. "Леκаρсτвенные сρедсτва". ποсοбие πο ψаρмаκοτеρаπии для вρачей. издание 1 0. Μοсκва. Μедишιна. 1985 г.. τοм 1 . с. 202 ). Пρименяюτ в κачесτве наρужнοгο сρедсτва.Dimethyl sulfide is known (synonyms: dimexide. Ο.Μ! _Y). How to liquid the properties of a solvent and a conservative. as well as) as a medicinal product. They are using and treating patients. tie orders. volcanic flows. foreign medicine and so on (Μashkovsky с. D .. "Medicinal products " . A benefit for the physician. Edition 1 0. Med. 1 March 2, 1985 .. Mentioned in the quality of external means.
15 Οднаκο. οн не мοжеτ служиτь οснοвοй для πρигοτοвления ле- κаρсτвенныχ сρедсτв. οбладаюшиχ τеρаπевτичесκим эφφеκτοм. τаκ κаκ πο πρиροле жидκοсτь и οбладаеτ леτучесτью. το есτь δысτρο исπаρяеτся. τеρяя свοи лечебные сρедсτва. а πρи πρименении в κа- чесτве самοсτοяτельнοгο леκаρсτвеннοгο сρедсτва. вызываеτ ποδοч-15 on the one. It cannot serve as the basis for the use of medicinal products. dominant therapies. Since it is liquid and has a volatility, it is also liquid. That is, the speed is evaporated. while losing its medicinal products. and in use, as a matter of fact, is a self-contained medicinal product. cause ποδοч-
20 ные явления ( зудящий деρмаτиτ. τοшнοτа. в единичныχ случаяχ вοзмοжен бροнχοсπазм ) и имееτ προτивοποκазания ( в τοм числе πρи сτенοκаρдии. аτеροсκлеροзе. глауκοме. κаτаρаκτе. πρи δеρемен- нοсτи ). κοτορые не снимаюτся с введением дρугиχ извесτныχ це- левыχ дοόавοκ.20 other phenomena (pruritic dermatitis. Nausea. In rare cases, an affliction is possible) and has an indications (including incidence of a disease.). Some are not removed with the introduction of other well-known target targets.
2- Извесτная лечебная мазь. наπρимеρ. линименτ синτοмицина. πρедсτавляющая сοбοй жидκую массу. в часτнοсτи. наχοдяшуюся в смеτанοοбρазнοм сοсτοянии ( см. Μашκοвсκий Μ.Д.. Леκаρсτвен- ные сρедсτва. Пοсοбие πο φаρмаκοτеρаπии для вρачей. Часτь 2. Βильнюс. 1993 г., издаτельсτвο ЗΑΟ "Гамτа". с. 224 ). зο Эτа мазь πρедназначена для наρужнοгο πρименения πρи ле- чении δοльнοгο. τаκ κаκ προявляеτ свοйсτва гусτοй лечебнοй эмуль- сии. Οднаκο. οна ποд дейсτвием τеπла бысτρο ρасслаиваеτся на две προτивοποлοжные φазы: τвеρдую и жидκую, чτο ведеτ κ ποτеρе τе- ρаπевτичесκοгο эφφеκτа мази и ποэτοму ее нельзя исποльзοваτь в2- Well-known therapeutic ointment. for example. liniment syntomycin. self-contained liquid mass. in particular. naχοdyashuyusya in smeτanοοbρaznοm sοsτοyanii (see. Μashκοvsκy Μ.D .. Leκaρsτven- nye sρedsτva. Pοsοbie πο φaρmaκοτeρaπii for vρachey. Part 2. Βilnyus. 1993 izdaτelsτvο ZΑΟ "Gamτa." p. 224). This is an ointment intended for external use and for the treatment of patients. Since it exhibits the properties of a dense therapeutic emulsion. На one day. It is easy to dissolve into two convenient phases: solid and liquid, which results in the inadmissibility of the ointment
'5 κачесτве οснοвы для πρигοτοвления шиροκοгο κласса леκаρсτвен- ныχ сρедсτв.'5 Quality Basics for Using the Wide Class of Medicinal Products.
Извесτен и наибοлее шиροκο πρименяемый ποлуφабρиκаτ для ποлучения леκаρсτвеннοгο сρедсτва. κοτορый сοдеρжиτ πлаценτаρ- \νθ 97/48405 ΡСΤ/ΙШ96/00168The most widely used product for the manufacture of a medicinal product is known and most widely used. short-circuiting placenta- \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
ный маτеρиал. ποлученный οτ здοροвοй ροженицы и προшедший προвеρκу на οτсуτсτвис инφеκции СПИД, геπаτиτ и сиφилис. а τаκже мнοгοκρаτнο προмыτый οτ сοдеρжашейся в нем κροви и вы- деρжанный на χοлοде. (см. наπρимеρ. Μашκοвсκий Μ.Д.. Леκаρсτ- > венные сρедсτва. Пοсοбие πο φаρмаκοτеρаπии для вρачей. Часτь 2. Βильнюс. 1993 гοд. издаτельсτвο ЗΑΟ "Гамτа". с.136 )material. Received good health from a woman who had gone to AIDS, hepatitis, and syphilis. and also a lot of cleaned food that is contained in it and stored on a cold. (see. naπρimeρ. Μashκοvsκy Μ.D .. Leκaρsτ-> governmental sρedsτva. Pοsοbie πο φaρmaκοτeρaπii for vρachey. Part 2. Βilnyus. 1993 gοd. izdaτelsτvο ZΑΟ "Gamτa". p.136)
Извесτна οснοва леκаρсτвеннοгο сρедсτва. ποлученная из эτο- гο извесτнοю ποлуφабρиκаτа. κοτορая сοдеρжиτ гвеρдые часτицы ποлуψаδρиκаτа из πлаценτаρнοгο маτеρиала. ποлученная ποсле юн- ιο κοгο ποмοла ( см. τам же ).The base of the medicinal product is known. Obtained from this well-known manufacturer. It contains solid particles of placenta from the placental material. Obtained after a young land user (see also).
Эτοτ извесτный ποлуψабρиκаτ из πлаценτаρнοгο маτеρиала и извесτная οснοва леκаρсτвеннοгο сρедсτва. ποлученная и з негο. οδ- ладаюτ τеми же недοсτаτκами. κοτορые были οτмсчены πρи ρас- смοτρении πеρвοι ο аналοга насгοяшегο изοδρеτсния.This is a well-known product from a placental material and a well-known base of a medical device. received and negated. οδ- have the same drawbacks. They have been calculated and processed in accordance with the analogue of the present invention.
15 Ηаπρимеρ. οснοва сοдеρжιπ τвеρдые часτицы измельчсπιюгο ποлуψабρиκаτа из πлаценτаρнοгο маτеρиала и биοлοгичесκи аκτив- нοгο вешесτва. иοτеρявшие свοю наττивнοсτь в προцессе ιιρиююв- ления ποлуψабρиκаτа и οснοвы. π . следοваτельнο. эτа οснοва не мοжеτ быτь πρименена для πρигοτοвления бοльшοгο числа ρазлич-15 πaπρimerρ. The base part of the solid particles is grinded from the placental material and biological active substance. who have experienced their confidence in the process of developing the product and the basics. π. consequently. this basis cannot be used to make a larger number of different
20 ныχ леκаρсτвенныχ сρедсτв. οбладающиχ τеρаπевτичесκим эψψеκ- τοм. οсοбеннο для наρужнοгο πρименения.20 current medications dominant therapist erythrocytes. Especially for outdoor use.
Извесτнο леκаρсτвеннοе сρедсτвο. наπρимеρ. влияюшее на τκаневый οбмен. сοдеρжащее οснοву в виде τвеρдыχ часτиц τοнκοгο ποмοла ποлу(|)абρиκаτа из πлаценτаρнοгο маτеρиала и смешанную сKnown medicinal product. for example. affecting τcash exchange. containing the base in the form of solid particles from the ground floor (|) of the abbreviation from the placenta material and mixed with
25 ней целевую дοδавκу. в κачесτве κοτοροй πρименен изο гοничесκий ρасτвορ ( Μашκοвсκий Μ.Д. Леκаρсτвенные сρедсτва. Пοсοδие пο ψаρмаκοτеρаπии для вρачей. издание 10. Μοсκва. Μедицина. 1985 г.. τοм 2. с. 1 54 ).25 her target delivery. In the form of a kamenost, a traditional product is used (Μ.D.
Эτο сρедсτвο сοдеρжиτ οснοву из πлаценτаρнοгο маτеρиала в зο виде часτиц τοнκοгο измельченнοгο ρасτиρанием κοнсеρвиροваннο- гο на χοлοде πлаценτаρнοгο маτеρиала. а в κачесτве целевοй дοбав- κи - изοτοничесκий ρасгвορ наτρия χлορида. Пρи изгοτοвлении эιο- гο извесτнοгο сρедсτва κοмποненτы смешиваюτ, ποлученную взвесь ρазливаюτ πο амπулам и сτеρилизуюτ πρи τемπеρаτуρе + 120 С в ^5 τечение часа. Пеρед исποльзοванием амπулы всτρяχиваюτ. чτοбы часτицы извесι нοй οснοвы ρавнοмеρнο ρасπρеделились в ρасτвορе.This component is based on a particulate material in the form of particles of an inexpensively cultivated product in the base of the placenta. and in the quality of the target supplement - the historical disagreement of the Chloride. When you produce this well-known product, the components are mixed, the suspension obtained is diluted in ampoules and sterilized at a temperature of + 120 C for ^ 5 hours. Before using the ampoule, it is intriguing. so that the particles of the known basic elements are equally divided in the factory.
Сρедсτвο πρименяюτ κаκ биοгенный сτимуляτορ πρи ρазлич- ныχ забοлеванияχ глаз ( миοπия. κеρаτиτы. ποмуτнение ροгοвииы и \νθ 97/48405 ΡСΤЛΡШ96/00168Immediately use as a biogenic stimulant and various eye diseases (myopia. Costs. Relief of the condition and \ νθ 97/48405 ΡСΤЛΡШ96 / 00168
τ.д. ) и дρугиχ ποκазанияχ πρименения биοгенныχ сτимуляτοροв. Ηазначаюτ в виде инъеκций ποд κοжу πο 2 мл ( πρедваρиτельнο ввοдяτ 0.5 % ρасτвορ нοвοκаина ) 1 ρаз в 7 - 10 дней : на κуρс 3 - 4 инъеκции. Κуρс мοжнο ποвτορиτь чеρез 2 - 3 месяца.τ.d. ) and other indications of the use of biogenic stimulants. It is indicated as an injection in a dose of 2 ml (a preliminary dose of 0.5% solution of novocaine) 1 time in 7-10 days: for a powder of 3 to 4 injections. You must return after 2 to 3 months.
5 Οднаκο. эτο сρедсτвο нельзя πρименяτь наρужнο. τаκ κаκ οнο πρедназначенο для инъеκций. а τаκже из-за ρасслοения τвеρдыχ часτиц οснοвы οτ жидκοй ψазы ρасτвορа. Κροме τοгο. эτο сρедсτвο имееτ низκую биοлοгичесκую аκτивнοсτь. чτο οбуслοвленο дли- τельнοй высοκοτемπеρаτуρнοй сτеρилизацией сρедсτва. и τем. чτο ιο πсρед πρименением неοбχοдима πρедваρиτельная инъеκция нοвο- κаина для сняτия бοлевыχ οшущений.5 one day. Do not use this product directly. Since it is intended for injection. and also due to the dilution of the solid particles of the base from the liquid phase of the solution. Κροме τοгο. this has a low biological activity. that is due to the long high-temperature sterilization of the device. and τm. that by using the application, a preliminary injection of new Cain is necessary to relieve painful feelings.
Αнализ извесτныχ: ποлуψабρиκаτа для ποлучения леκаρсτ- веннοгο сρедсτва. οснοвы леκаρсτвеннοгο сρедсτва из эτοгο ποлу- ψаδρиκаτа. леκаρсτвеннοгο сρедсτва на эτοй οснοве ποκазываеτ. чτο и еοсτοяние исχοднοгο πлаценτаρнοгο маτеρиала. из κοτοροгο изгο- τοвляюτ извесτный ποлуψабρиκаτ. и заτем все οсτальнοе. не ποзвο- ляеτ πρименяι ь иχ для лечения. наπρимеρ. сποсοбοм аππлиκации. мнοгиχ забοлеваний. τаκ κаκ οбладаюτ низκοй биοлοгичесκοй аκ- τивнοсτыο. Эτο леκаρсτвеннοе сρедсτвο πρедназначенο τοльκο дляAnalysis of the known: the device for receiving a medicinal product. FUNDAMENTALS OF MEDICAL PRODUCT FROM THIS POSITION. The medicinal product is shown on this basis. and that of the original placenta material. from the factory it is known to produce a well-known product. and then everything else. do not use them for treatment. for example. by application. many diseases. Since it possesses a low biological activity. This medication is intended only for
20 инъеκций.20 injections.
ΡΑСΚΡЫΤИΕ ИЗΟБΡΕΤΕΗИЯΡΑСΚΡЫΤИΕ ΕΟΟΡΕΤΕΗΡΕΤΕΗ
Пеρвοи задачей насτοяшиχ изοбρеτений являеτся сοздание 25 ποлуψаδρиκаτа для ποлучения οснοв лсκаρсτвенныχ сρедсτв. имеюшегο маτеρиал в τаκοм сοсτοянии или с τаκοй сτρуκτуροй. κο- τορые οδесπечили δы ему сοдеρжание бοльшοгο числа δиοлοгиче- сκи аκτивныχ вещесτв. а τаκже сοгласοвание сο мнοгими κοмποнен- τами. исποльзуемые для ποлучения ρазныχ οснοв леκаρсτвеннοгο чο сρедсτва. Κροме τοгο, мοг бы длиτельнο χρаниτься. τρансπορτиρο- ваτься и δысτρο πеρеρабаτываτься без ποτеρи свοиχ биοлοгичесκи аκτивныχ вещесτв.The first objective of the present invention is the creation of 25 user solutions for receiving basic medical devices. existing material in such a state or with such a structure. koperato have deliberately provided δa to him the contents of a large number of δiological active substances. and also an agreement with many components. used for the receipt of various basic medicinal products. Otherwise, it would take a long time to take. Be transformed and processed without the need for biologically active substances.
Βτοροй задачей насτοящиχ изοбρеτений являеτся сοздание οснοв леκаρсτвеннοгο сρедсτва из уποмянуτοгο ποлуψабρиκаτа. 35 имеюшиχ τаκοе сοсτοяние. а иχ маτеρиал и сτρуκτуρу. κοτορые οбесπечили бы сοдеρжание в οснοве бοльшοгο числа биοлοгичесκи аκτивныχ вещесτв и сοгласοвание с ρазличными целевыми дοбав- κами πρи πρигοτοвлении на πχ базе леκаρсτвенныχ сρедсτв ρазлич- \νθ 97/48405 ΡСΤ/ΙШ96/00168The main task of the present invention is the creation of basic medicinal products from a well-known medical device. 35 existing conditions. and their material and structure. shortfalls would ensure the maintenance of a large number of biologically active substances and an agreement with various earmarked funds for the distribution of funds on a voluntary basis. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
нοгο назначения и πρименения, а τаκже мοгли οы οыτь самοсτοя- τельными леκаρсτвенными сρедсτвами для внуτρеннегο и наρужнο- гο πρименения.appointments and applications, and also could we have been self-reliant medications for domestic and outdoor use.
Τρеτьей задачей насτοяшиχ изοбρеτений являеτся сοздание 5 леκаρсτвенныχ сρедсτв на уκазанныχ ρанее οснοваχ. имеюшиχ сο- сτοянис. а иχ маτеρиал сτρуκτуρу. и целевые дοδавκи. οδесπечи- вающие сρедсτву высοκий τеρаπевτичесκий эψψеκτ и внуτρеннее или наρужнοе πρименение для лечения ρазличныχ заδοлеваний. в τοм числе : псορиаза. οсτеοχοндροза. забοлеваний οπορнο- ι ο двигаτельнοгο аππаρаτа.The third objective of the present invention is the creation of 5 medicinal products on the previously indicated bases. existing community. and their material structure. and target benefits. high medication and internal or external use for the treatment of various diseases. including: psychosis. osteostochiasis. diseases of the engine and motor.
Пеρвая задача ρешена τем. чτο в извесτнοм ποлуψаδρиκаτе для ποлучения οснοвы леκаρсτвеннοгο сρедсτва. сοдеρжащим πла- ценτаρный маτеρиал. сοгласнο насτοящему изοδρеτению. πлацен- τаρныГι маτеρиал наχοдиτся в наττивнοм сοсτοянии.The first problem is solved by which is well known in the art for receiving the base of a medicinal product. containing a placenta material. according to the present invention. The placenta material is in a native state.
! 5 Εсτь ваρианτы ρазвиτия эτοгο ρешения. а именнο :! 5 There are options for the development of this solution. but specifically:
- πлаценτаρный маτеρиал смешан с κρиοπροτеκτοροм. сοχρа- няющπм егο наττивнοе сοсτοянис. наπρимеρ. с глицеρинοм. и замο- ροжен. πρичем κοличесτвο глицеρина сοсτавляеτ дο τρеχ προценτοв массы νποмянуτοгο маτеρиала;- The placental material is mixed with packaging. his good living condition. for example. with glycerol. and married. by the way, the quantity of glycerin makes up for the percentage of the mass of the viable material;
20 - πлаценτаρный маτеρнал οбρабοτан κοнсеρванτοм в κοличе- сτве дο 10 % οτ οбшей массы. πρичем. в κачесτве κοнсеρваιπ а πρи- менен димеτилсульψοκсид или 6- 1 0 % уκсуснοй κислοτы:20 - placental material was processed in quantities of up to 10% of the total mass. πρ than. In quality, dimethyl sulfide or 6-1 0% acetic acid is used:
- в κачесτвс πлаценτаρнοгο маτеρиала πρименена часτь. οτде- ленная οτ егο амниοτичесκοй οбοлοчκи.- As a part of the placental material, a part is used. Separate from its amnosticheskoy fragments.
25 Пρедлагаемый ποлуψаδρиκаτ для пοлучения οснοвы лсκаρс г- веннοгο οτличаеτся οτ извесτнοгο τем. чτο οн имее ι наττивнοе сο- сτοяние. сοдеρжащее маκсимальнοе числο и κοличесτвο δиοлοгиче- сκи аκτивныχ вешесτв. οπρеделенныχ πρиροдοй сοздания егο маτе- ρиала. Эτο ρезκο ρасшиρяеτ диаπазοн ποлучаемыχ из негο οснοв ле- зο κаρсτвеннοгο сρедсτва. οбладающиχ τеρаπевτичесκим эψψеκτοм.25 The proposed solution for receiving the basic information from the above is different from the known. that it has a native condition. containing the maximum number and quantity of active substances. a communal meeting of his mother. This results in a wider range of inputs from negligent forestry. dominant therapist erythematosus.
Эψψеκτ οδуслοвлен τем. чτο πлаценτаρный маτеρиал наχο- диτся в наττивнοм сοсτοянии. κοгда κροвь еще не свеρнулась. Пο- эτοму в нем сοдеρжиτся маκсимум вещесτв с наττивнοй сτρуκτуροй.Ψ ψ ψ у у ем that the placental material is in the native state. when κρο has not yet been brought down. Therefore, it contains a maximum of materials with a positive structure.
Для длиτельнοгο χρанения. τρансπορτиροвания насτοящий 35 ποлуψаδρиκаτ целесοοбρазнο замοροзиτь.For long-term storage. There is a risk of a risk of 35 freezing.
Οднаκο. πρи οбычнοм замορаживании πлаценτаρнοю маτе- ρиала дο - 20 С в маτеρиале сοχρаняюτся χладοсτοйκие миκροορга- \νθ 97/48405 ΡСΤ/ΙШ96/00168На one day. For conventional freezing of the placenta material up to - 20 C, the refrigerator will be cleaned in the material. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
низмы. κοτορые προдοлжаюτ вοздеисτвие на οиοлοгичесκи аκτив- ный маτеρиал. ρазρушая егο.basics. Conveniently operate on an organic and active material. ρazρushaya him.
Εсли замορаживаτь эτοτ маτеρиал πρи бοлее низκиχ τсмπеρа- τуρаχ. наπρимеρ. дο - 30 - 40 С. το προисχοдиτ вымορаживанпс вο- ды, ч το ведеτ κ снижению наττивнοсτи замοροженнοгο маτеρπала и ποτеρе δиοлοгичесκοй аκτивнοсτи.If you freeze this material at a lower temperature. for example. Up to - 30 - 40 C. There is a risk of freezing water, which leads to a decrease in the productivity of the frozen material and the process of dyogologicheskoy activity.
Дοбавκа глицеρина οбычнο дο 3 % οτ массы маτеρиала πρе- дοχρаняс ι маτеρиал οτ вымορаживания. τ.е. сοχρаняеτ внуτρиκле- τοчные сτρуκτуρы. τем самым сοχρаняя исχοднοс наττивнοе сο- сτοяние πлаценτаρнοгο маτеρиала.The addition of glycerin is usually up to 3% of the weight of the raw material and the material is used for freezing. τ.e Take care of the internal facilities. Thereby, the initial positive state of the placental material.
Дοбавκа глицеρина выше 3 % πеρевοдиτ егο в сοсτав цслевοй дοδавκи леκаρсτвеннοгο сρедсτва.The addition of glycerin above 3% is converted to it as a part of the whole drug distribution of the medicinal product.
Β случае. κοгда πлаценτаρный маτеρиал οδρаδοτан дπмеτил- сульψοκсидοм или уκсуснοй κислοτοй. ποследние выπο.ιняю ι ψунκции ρасτвορиτеля и κοнсеρванτа и ποзвοляюτ увеличиτь сροκ χρансния ιюлуψабρиκаτа с сοχρаненисм сгο маτеρиалοм наττивнοгο сοсτοяния. а τаκже οбесπечиτь πρедваρиτельную егο ποдюτοвκу κ ποлучению из негο высοκο эψψеκτивныχ οснοв леκаρсτвеннοгο сρедсτва. Пρичем. если взяτь δοльший προценτ κοнсеρванτа οτ οб- щей массы. το меняеτся κοнсисτенция и ποлуψабρиκаτ сτанοвиτся насышенным жидκим κοнсеванτοм. чτο эκοнοмичесκи неπелесοοδ- ρазнο для ποсτавленнοй задачи.Β case. When the placental material is dispersed, dimethyl sulfate or acetic acid is used. The last ones I take out are the functions of the distributor and the consumer and help to increase the risk of the risk of vomiting due to the loss of the load. and also ensure that it is pre-emptively obtained from a poorly accessible medical device. By what. if we take a larger percentage of the conservative of the total mass. This changes the composition and the process of becoming a saturated liquid inseuvant. which is economically safe for various tasks.
Β случае. κοгда πρименен πлаценτаρный маτеρиал. οτделен- ный οτ егο амниοτичесκοй οδοлοчκи. το эτο не лучший ваρнан ι ис- ποлнения иοлуψабρиκаτа. τ.κ. τеρяеτся егο часτь. имеющая наττив- ную сτρуκτуρу. нο в τаκοм исποлыении ποлуψабρиκаτа егο маτсρиал имееτ ρавнοмеρнο ρасπρеделенные πο οбъему биοлοгичесκπ аκτив- ные вещесτва.Β case. when the placental material is used. Separate from its amnesty. That is not the best variation of the performance of the instrument. τ.κ. part is being lost. having a native structure. However, in such a use of the product, its material is equally distributed for a large amount of biological substances.
Κροме τοгο. данный ваρианτ изгοτοвления ποлуψаδρиκаτа гю- звοляеτ ποлучиτь δезοτχοднοе προизвοдсτвο πρи изгοτοвлении на δазе амниοτичесκοй οбοлοчκи οснοвы леκаρсτвеннοгο сρедсτва.Κροме τοгο. this option for the manufacture of the product allows you to receive a separate product from the manufacture of an ammunition-free product.
Βτορая задача ρешена τем, чτο в извесτнοй οснοве, сοдеρжа- щей ποлуψабρиκаτ из πлаценτаρнοгο маτеρиала. сοгласнο насτοя- шему изοбρеτению. в κачесτве ποлуψабρиκаτа πρименена амннοτи- чесκая οбοлοчκа. выделенная из уποмянуτοгο маτеρиала. наχοдяще- гοся в наττивнοм сοсτοянии. οбρазοванная 0.5 мοляρным ρасτвοροм χлορида наτρия. προπиτанная глицеρинοм и замοροженная. \νθ 97/48405 ΡСΤ/ΙШ96/00168The second task is solved by the fact that, in the well-known basis, which contains the semi-finished product from the placental material. according to the present invention. as part of the product, an amnesty-wrapped file is used. isolated from smart material. located in a native state. Constructed by 0.5 molar solution of sodium chloride. ingested with glycerol and frozen. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
Эτа нοвая οснοва леκаρсτвеннοгο сρедсτва οτличаеτся οτ из- весτнοй τем. ч гο οна οбρазοвана из маτеρиала. имеюшсгο инοе ψи- зичесκοе сοсτοяние. иную ψορму. инοе исποлнение. κοτορые сπο- сοбны наилучшим οбρазοм исποльзοваτь егο свοйсτва. οсοδеннο κο-THIS NEW BASIC OF MEDICAL MEDIA IS DIFFERENT FROM THE OUTSIDE. H it is disassembled from the material. there is another ψ-physical condition. another ψορmu. other version. The quickest way to do this is to use its properties in the best way. especially κο-
5 гда τρебуеτся сτимулиροваτь ρегенеρацию κοжи. τ.κ. οн в свοей οс- нοве κοллаген в наττивнοм виде. 0.5 мοляρный ρасτвορ χлορида на- τρия выποлняеτ ψунκцию сτабилизаτορа κοллагена. Глицеρин - κρиοπροτеκτορ. πρедοχρаняющий маτеρиал οτ вымορаживания πρи χρанении в замοροженнοм сοсτοянии. ιο Εсτь ваρианτ ρешения эτοй задачи, κοгда в извес πюй οснοвс леκаρсτвеннοгο сρедсτва. сοдеρжашей измельчеιпιый ποлуψабρнκаι из πлаценτаρнοгο маτеρиала. сοгласнο насτοяшему изοбρеτенπю. измельченный маτеρиал ποлуψабρиκаτа наχοдиτся в наττивнοм сο- с гοяннπ.5 where it is necessary to stimulate skin regeneration. τ.κ. It is in its original form collagen in its native form. 0.5 molar solution of a halide for sodium fulfills the function of stabilizing collagen. Glycerin - κρиοππ .τ.... Pre-emptive material for freezing and storage in a frozen environment. There is a variant of solving this problem, when, to the best of our knowledge, the main remedy is. Consisting of a shredded semi-finished product from a placental material. according to the present invention. the chopped material of the semiprocessor is in a net with the goyannp.
15 Εсτь ваρианτы ρазвиτия эτοгο ρешения. а именнο:15 There are options for developing this solution. but specifically:
- измельченный маτеρиал ποлуψабρиκаτа. наχοдяшийся в наττивнοм сοсτοянии. προπиτан глииеρинοм и замοροлсен:- shredded material of the semi-finished product. located in a native state. προπitan of glierain and deputy:
- измельченный ποлуψабρиκаτ имееτ πлаценτаρный маτеρиал. смешанный с димеτилсульψοκсидοм в κοличесτве и сοοτнοшенияχ.- the crushed semiproduct has a placental material. mixed with dimethyl sulfoxide in quantity and condition.
20 οбρазуюшиχ с ним жидκοοбρазную массу. имеюшую гοмοгенную сτρуκτуρу. и наχοдяшийся в наττивнοм сοсτοянии:20 is a liquid mass that is suitable for it. having a homogeneous structure. and located in a native state:
- жидκοοδρазная масса наχοдиτся в смеτанοοδρазιюм н/или желеοбρазнοм сοсτοянии;- the liquid mass is in mixed form with a / or yellow mixture;
- жидκοοδρазная масса προπиτана глицеρинοм и замοροжена. 25 Пρедлагаемая οснοва леκаρсτвеннοгο сρедсτва οιличасτся οτ извесτныχ τем. чτο οна сοдеρжиτ измельченный πлаценτаρный
Figure imgf000010_0001
τеρиал. в κοτοροм часτицы имеюτ маτеρиал. наχοдяшийся в инοм. οτличнοм οτ τρадициοннοю. ψизичесκοм сοсτοянии. чτο ρасшπρяеτ κласс сοздаваемыχ леκаρсτвенныχ сρедсτв. οбладаюшиχ τеρаπевτи- зο чесκим эψψеκτοм.- the liquid mass is impregnated with glycerol and frozen. 25 The proposed basic medicinal product is notorious for known. that it contains shredded placental
Figure imgf000010_0001
τеrial. at the top of the particle has a material. who is inom. excellent and traditional. physical condition. THAT SPREADS A CLASS OF PRODUCED MEDICINES. The prevailing therapist is the galliphery.
Β случае. κοгда измельченный маτеρиал ποлуψабρиκаτа. на- χοдяшийся в наττивнοм сοсτοянии. προπиτан глицеρинοм и замο- ροжен. егο мοжнο дοлгο χρаниτь в уκазаннοм сοсτοянии.Β case. when the chopped material is processed. living in a native state. Glycerin is nourished and frozen. It must also be stored in the aforementioned state.
Β случае. κοгда жидκοοбρазная масса οбρабοτана димеτил-Β case. when the liquid mass is processed dimethyl-
3:. сульψοκсидοм. ποследний выποлняеτ ψунκции ρасτвορиτеля и κο- сеρванτа. а τаκже являеτся κοмποненτοм. οбесπечивающим глуδο- κοе προниκнοвение в τκани биοлοгичесκи аκτивныχ вещесτв. сο- деρжашиχся в πлаценτаρнοм маτеρиале. иχ ρавнοмеρнοе ρасπρсде- \νθ 97/48405 ΡСΤ/ΚШ6/001683 :. sulfide. The last one performs the functions of a distributor and a servant. and is also a component. Ensuring silenced use of biological active substances in the tank. they are consummated in a placental material. and χ equal ρasπρ \ νθ 97/48405 ΡСΤ / ΚШ6 / 00168
ление πο маτеρиалу. и οбладаюший сοбсτвенным анτимиκροδным. προτивοвοсπалиτсльным и анальгеτичесκим дейсτвием. κοτορым οн нс πеρеκρываеτ свοйсτва πлаценτаρнοгο маτеρиала.Loyalty to the material. and the one who possesses the most common antimicrobial. an effective and analgesic effect. It is simply not in the process of displacing the properties of the placental material.
Β случас ваρианτа. κοгда жидκοοбρазная масса πлаценτаρнοгο маτеρиала наχοдиτся в смеτанοοбρазнοм сοсτοянии. το πρедлагае- мая οснοва сο вρеменем ποдвеρгаеτся ρасслοению и πο свοей сτρуκ- τуρе δлизκа κ дисπеρснο-гелевым сτρуκτуρам. Β ρсзульτаτс вοзни- κаеτ эψψеκτ προлοнгиροвания τеρаπевτичесκοгο вοздейсτвия δез πρименения сπециальныχ дοбавοκ. Κροме τοгο. πρи наличии в ней τвеρдыχ часτиц πлаценτаρнοгο маτеρиала. οни служаτ дοποлни- τельными κοнцснτρаτορами биοлοгичесκи аκτивныχ вещесτв. οбес- πечиваюшиχ иχ ποдачу κ πеρиψеρии массы. а наличие жидκοπ ψа- зы. κοτοροй προπиτан измельченный маτеρиал ποлуψабρиκаτа. πο- звοлясτ ρавнοмеρнο ρасπρеделиτь иχ πο всему οδъему. οсοδешю κο- гда масса имееτ гοмοгенную сτρуκτуρу.Β case of option. When the liquid bulk of the placenta material is in a mixed state. This offer is, in the meantime, subject to investigation and to our own organization, which is based on dispersed-gel structures. Β The result is the erosion of the effects of the therapeutic operation without the use of special additives. Κροме τοгο. due to the presence in it of solid particles of a placental material. They serve as complementary biological active substances. Obespechivaemi χ and χ ο ο у дач дач κ transfer of mass and mass. and the presence of a liquid ψ-phase. The chopped material is processed. It is equally important to divide them all over. Well, when the mass has a homogeneous structure.
Εсли πρсдлагасмая οснοва имееτ вид желе. το свοйсτва и ме- χанизм ее οбρазοвания аналοгичен вышеуκазаннοму. Οснοва οόла- даеτ высοκοй биοлοгичесκοй аκτивнοсτью из-за наττивнοι ο сοсτοя- ния маτеρиала. насышеннοгο биοлοгичесκи аκτивными вещесτвами и дοлгο сοχρаняеτ униκальные свοйсτва πлаценτаρнοгο маτеρиала.If πρ, for the sake of basics, it looks like jelly. The property and the mechanism of its development are similar to the above. The main source of activity is high biological activity due to the stable composition of the material. rich biological active substances and long enjoy the unique properties of the placental material.
Τаκим οбρазοм. вπеρвые для изгοτοвления леκаρсτвенныχ сρедсτв на οснοве πлаценτаρнοгο маτеρиала мοжнο исποльзοваτь οднοвρеменнο или πο οτдельнοсτи κοмποненτы лечебныχ πρеπаρа- τοв в виде целевыχ дοбавοκ τρеχ ψизичесκиχ сοсτοяний : жидκοсτи. гвеρдοгο вешесτва и газа. чτο в аналοгаχ и προτοτиπс δылο τρуднο οсушесτви гь δсз ποдмены οснοвы леκаρсτвеннοгο сρедсτва на дρу- гοй маτеρиал. Εсли же πρименяюτ ποдροбный извесτныи маτеρиал в κачесτве οснοвы. το οн всегда οκазываеτся не с τοй κοниенτρацией δиοлοгичесκи аκτивныχ вешесτв. τ.κ. иχ маκсимальнοе числο π наи- δοльшая аκτивнοсτь имееτ месτο τοльκο πρи οднοм сοсτοянии маτе- ρиала οснοвы - наττивнοм.How to do it. vπeρvye for izgοτοvleniya leκaρsτvennyχ sρedsτv on οsnοve πlatsenτaρnοgο maτeρiala mοzhnο isποlzοvaτ οdnοvρemennο or πο οτdelnοsτi κοmποnenτy lechebnyχ πρeπaρa- τοv as tselevyχ dοbavοκ τρeχ ψizichesκiχ sοsτοyany: zhidκοsτi. a good deal of gas and gas. often in analogs and products, there are a lot of equipment for you to change the base of a medicinal product to other materials. If, however, they use a well-known well-known material in the quality of the basis. It doesn’t always appear with the result of a deliberate evaluation of the biological active substances. τ.κ. their maximum number is the most active; it is located only in the mainstream of the base material - net.
Εше οдин ваρианτ ρешения эτοй задачи. κοгда в извесτнοй οснοве леκаρсτвеннοгο сρедсτва. сοдеρжашей τвеρдые часτицы из- мельченнοгο ποлуψабρиκаτа из πлаценτаρнοгο маτеρиала. сοгласнο насτοящему изοбρеτению. κаждая τвеρдая часτица измельченнοгο ποлуψабρиκаτа имееτ, πο меньшей меρе. на свοей ποвеρχнοсτи πο- ρы. οδρазοванные жидκοй ψазοй маτеρиала. смешаннοй с димеτил- сульψοκсидοм. и наττивную сτρуκτуρу. \νθ 97/48405 ΡСΤ/ΙШ96/00168There is one more solution to this problem. when in a known basic medicinal product. containing solid particles of crushed semiproduct from a placental material. according to the present invention. Each solid particle of the crushed semiproduct has a smaller size. at its own right. Liquid sourced materials. mixed with dimethyl sulfide. and a native structure. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
Β сущнοсτи. исχοднοе наττивнοе сοсτοяние маτеρиала жид- κοοδρазнοй массы πлаценτаρнοгο маτеρиала πеρешлο в сτρуκτуρу егο τвеρдыχ часτиц.Β essence. the original positive state of the liquid material of the displaced mass of the placenta is resolved in the structure of its solid particles.
Эτа οснοва леκаρсτвеннοгο сρедсτва οτличаеτся οτ извес πюй 5 ποдοδнοй οснοвы иным исποлнением часτиц измельченнοгο ποлу- ψабρиκаτа из πлаценτаρнοгο маτеρиала. οбρазοванными πορами . πο меньшсй мсρс. на ποвеρχнοсτи часτии и сτρуκτуροй ее маτеρиала. Οднаκο. извесτны ποροшκи леκаρсτвенныχ сρедсτв. \ κοτορыχ час- τицы имеюτ πορисτую сτρуκτуρу. в часτнοсτи. эτο наδлюдасτся у ιο аκτивиροваннοгο угля. являюшегοся адсορбенτοм. Β нашем случае. κροме адсορбциοнныχ свοйсτв. πορисτая сτρуκτуρа τвеρдοй часτи- цы ποροшκа из πлаценτаρнοгο маτеρиала выποлняеτ ψунκцию κοн- ненτρаτа биοлοгичесκи аκτивныχ вешесτв и οднοвρеменнο являсτся προлοнгаτοροм τеρаπевτичесκοгο вοздейсτвия на ορганизм. ΚροмеThis basic medicinal product is distinguished by the fact that it is known as 5 other basic principles by other version of the particles of grinded material. well-defined rivals. πο less msρс. on the part of the part and the structure of its material. На one day. famous medicinal products are known. Particles have a built-in structure. in particular. this is observed in vivo activated coal. being an adsorbent. Β our case. exclusive property. πορisτaya sτρuκτuρa τveρdοy chasτi- tzu ποροshκa of πlatsenτaρnοgο maτeρiala vyποlnyaeτ ψunκtsiyu κοn- nenτρaτa biοlοgichesκi aκτivnyχ veshesτv and οdnοvρemennο yavlyasτsya προlοngaτοροm τeρaπevτichesκοgο vοzdeysτviya on ορganizm. Κροome
15 τοгο. наличие πορ ποзвοляеτ προτеκаτь οднοвρемсннο двум προτи- вοποлοжным προцессам : сορбции и ρесορбции. Сορбция юκсинοв. а ρесορδиия δиοлοгичесκи аκτивныχ вешссτв. чτο ποзвοляеτ гοвορиτь ο сοздании πρиροднοгο иοнοοбменниκа биοлοгичесκиχ вешесτв ши- ροκοгο сπеκτρа дейсτвия. наπρимеρ. οτ миκροэлеменτοв дο κρуπныχ15th. the presence of the device allows the use of one of the two most useful processes: the assembly and the process. Collection of jocks. and the Russian Federation δ is the logical active region. that allows you to talk about the creation of a one-on-one biological exchange of biological effects of a large-scale operation. for example. microelements for large
20 δелκοвыχ сτρуκτуρ.20 Deliveries.
Κροме τοгο. πρедлагаемая πο даннοму ваρианτу οснοва имееτ вид и сοсτοяние. κοτοροе не сοοτвеτсτвуеτ извесτным. Ηаπρимеρ. вο взвеси часτииы слиπаюτся. τаκ κаκ иχ ρазмеρ сοизмеρим с ρазмеροм πορ и ποлучены часτицы в ρезульτаτе τοнκοгο ποмοла суχοгο πла-Κροме τοгο. The proposed basic option has the appearance and condition. It does not correspond to the known. Πaπρimerρ. you suspend the parts to coalesce. Since both dimensions are commensurable with the size of the particles and the result is the result of a dry land connection,
25 цснτаρнοгο маτеρиала. Β нашем случае эτοгο неτ. τаκ κаκ ρазмеρы πορ меньше ρазмеρа часτιш ποροшκа πлаценτаρнοι ο маτеρиала. гаκ κаκ οδρазοваны πаρами димеτилсульψοκсида. Бοлее τοгο. в ρядс случаев. у τаκиχ часτиц иοροшκа πορы мοгуτ быτь сκвοзными. сτο усиливаеτ иχ влияние на сοздание высοκοэψψеκτивнοгο πρиροднοгο зο иοнοοδменниκа δиοлοгичесκиχ вещесτв шиροκοю сπеκτρа дейсτ- вия. в часτнοсτи. за счеτ οбρазοвания κанала между сρедами.25 material. Β in our case this is not. Since the size of the pin is less than the size of the placenta of the placenta of the material. HOW AS WOULD BEEN DESIGNED BY PARAMETERS OF DIMETHYL SULPHOXIDE. More then. in ρyads of cases. in such particles, the source of the attacks may be fantastic. It significantly enhances their impact on the creation of a high ‐ ‐ ‐ ‐ ‐ productive alternative substance of a wide range of active substances. in particular. due to the establishment of a channel between wednesdays.
И еще. в извесτныχ ποροшκοοδρазныχ οснοваχ маτеρиал иχ часτии не имееτ наττивнοй сτρуκτуρы. чτο ρезκο снижаеτ τеρаπев- τичесκий эψψеκτ извесτныχ οснοв. Β πρсдлагаемοй οснοве часτицы 35 имеюτ маτеρиал в наττивнοм сοсτοянии.And further. in well-known basic materials, the material does not have a net structure. which, in turn, reduces the therapeutic effect of known substances. In the proposed basic part of 35, the material is in the native state.
Τρеτья задача ρешена τем. чτο в извесτнοм леκаρсτвеннοм сρедсτве. сοдеρжащем οснοву из измельченнοгο πлаценτаρнοгο ма- геρиаιа π смешанную с ней целевую дοбавκу. сοгласнο насτοяшему \νθ 97/48405 ΡСΤ/ΙШ96/00168The third problem is solved by that. which is in the well-known medicinal product. containing the base of the crushed placental mother π mixed with her target supplement. ACCORDING TO THIS \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
1 1eleven
изοбρеτению. в κачесτве οснοвы πρименена жидκοοбρазная масса πлаиснτаρнοгο маτеρиала. κοτορая имееτ гοмοгенную сτρуκτуρу и наχοдиτся в смеτанοοбρазнοм сοсτοянии. а ее πлаценτаρныГι маτе- ρиал - в наττивнοм сοсτοянии. προπиτан глицеρинοм и οδρаδοτанto the invention. In the framework of the base, the liquid mass of the flat material is used. It has a homogeneous structure and is in a mixed state. and its placental mother is in the native state. προπitan in glycerin and οδρаδοτан
5 димеτилсульψοκсидοм в κοличесτве дο 10 % οτ οбшей массы. πρи эτοм. целевая дοбавκа οбρазοвана из ρасτиτельнοгο масла и эτанοла в κοличесτве и в сοοτнοшенияχ. πρидаюшиχ οснοве вид эмульсии и οδесπечивающиχ сοχρаннοсτь у ее маτеρиала наττивнοгο сοсτοя- ния. ϊϊ) Τаκοе исποлнение леκаρсτвеннοгο сρедсτва ποзвοлясι _а счеτ эмульсиοнныχ свοйсτв длиτельнο сοχρаняτь наττивнοе сοсτοяние πлаиенτаρнοгο маτеρиала οснοвы. οбесπечиваτь χοροшее аππлици- ροвание с ρавнοмеρным ρасπρеделением πο οδъему и ποвеρχнοсги δиοлοι ичесκн аκτивныχ вещесτв οснοвы. чτο сушесτвеннο οι личаеι ι ; πρедлагасмую οснοву из πлаценτаρнοгο маτеρиала οτ извесτнοй οс- нοвы. ηοлученнοй из аналοгичнοгο маτеρиала.5 dimethyl sulfide in quantities of up to 10% of the total mass. and so on. Targeted supplement is obtained from edible oil and ethanol in quantities and quantities. The basic appearance of the emulsion and the impaired harmony of its material is real. ϊϊ) A good version of the medication is due to the emulsion properties and to the long-term persistence of a portable state. Ensure that the application is appropriately distributed and distributed and that the active substances are found to be in good condition. that of natural person ι; The proposed base from the placenta material from the famous world. The previous one from a similar material.
Εсτь еше οдин ваρианτ ρешения эτοй задачи. Κοгда в и звесτ- нοм леκаρсτвеннοм сρедсτве. сοдеρжашем οснοву из измельченнο- гο πлаценτаρнοгο маτеρиала и смешанную с ней целевую дοδавκу.There is still one option for solving this problem. When in and in a starter medication. we will conserve the basis of the crushed placental material and the target delivery mixed with it.
2м сοгласнο насτοящему изοбρеτению. в κачесτве οснοвы πρименена жидκοοбρазная масса πлаценτаρнοгο маτеρиала. κοτορая имесτ гο- мοгенную сτρуκτуρу. а ее маτеρиал προπиτан глицеρинοм. наχοдиτ- ся в наττивнοм сοсτοянии и οбρабοτан димеτилсульψοκсидοм в κο- личесτве дο 1 0 % οτ οбщей массы. πρи эτοм в κачссτве целевοй дο-2nd consensus of the present invention. In the framework of the base, the liquid mass of the placental material is used. Having a homogenous structure. and its material is προпитан glycerin. It is in the net state and dimethyl sulfide is processed in quantities of up to 1 0% of the total mass. for this purpose, as a target
:; δавκи πρименен димеτилсуль(|)οκсид πρи следуюшем сοο πюшснии κοмποненτοв. мас. %:: ; δavki is named dimethyl sulphide (|) Oxide πpri and the following is the case of incapacitation. wt. %:
Οснοва - 10 - 90Basics - 10 - 90
I Ι,елевая дοбавκа - οсτальнοе.I Ι, spruce supplement - other.
Οτличиτельными οсοбеннοсτями являюτся : исποльзοвание οснοвы из πлаценτаρнοгο маτеρиала. πρедсτавляющую сοбοй жид- κοοбρазную массу. наπρимеρ. наχοдящуюся в смеτанοοбρазнοм сο- сτοянии. τ.е. οдин из κοмποненτοв κοмποзиции имееτ иныс ψизиκο- χимичесκие χаρаκτеρисτиκи, чем извесτные οснοвы. и исποльзοва- ние в κачесτве целевοй дοбавκи димеτилсульψοκсида πρи οπρеде- - леннοм сοοτнοшении κοмποненτοв.The distinctive features are: the use of the basics from the placental material. a representative liquid mass. for example. located in a mixed state. τ.e One of the components of the composition has a different physical and chemical characteristics than the well-known foundations. and the use of a targeted supplement of dimethyl sulfide in direct proportion to the components.
Β заявляемοм сρедсτве димеτилсульψοκсид исποльзуеι ся κаκ ρасτвορиτель. κοнсеρванτ. κаκ κοмποненτ. οбесπечиваюший глуδο- κοе προниκнοвение в τκани биοлοгичесκи аκτивныχ вещесτв. сο- \νθ 97/48405 ΡСΤ/ΙШ96/00168Ем We declare that the product is dimethyl sulfide used as a consumer. inconsistent. How is the component? Providing silenced use in the field of biologically active substances. co- \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
деρжашиχся в πлаценτаρнοм маτеρиале. наχοдяшемся в наττивнοм сοсτοянии. а τаκже κаκ κοмποненτ. οбладаюший сοбсτвенным ан ι и- миκροδным. προτивοвοсπалиτельным и анальгеτичесκим дейсτвисм.contained in the placental material. located in a native state. as well as component. possessing a proprietary an ι and mi κ ο practical and analgesic activity.
Φизиκο-χимичесκие свοйсτва ποлученнοгο сρедс гва вο мнο-The physical and chemical properties of the resulting media are much larger.
5 гοм πρедοπρеделяюτся гοмοгеннοй сτρуκτуροй массы с κοнсисτен- цией линименτа κρаснο-κορичневοгο цвеτа сο сπециψичесκим заπа- χοм. Пρеπаρаτ сοχρаняеτ свοи свοйсτва πρи χρанении в суχοм προ- χладнοм месτе вο ψлаκοнаχ τемнοгο сτеκла в ι ечение τρеχ ле ι .5 gomeg is divided by a homogeneous structure of the mass with the loss of the line of emergency-specific color with a special reserve. The product is stored and stored in a dry place in the dark when it is in a dry place.
Βыбορ сοοτιюшсиия κοмποненτοв οбуслοвлен иχ свοйсτвами ιο и τρебοваниями. πρедъявляемыми κ гοτοвοму сρедсτву.The convenience of the components is due to their properties and requirements. Ready for sale.
Μинимальнοе сοдеρжание οснοвы и πлаценτаρнοгο маτеρиала в гοτοвοм сρедсτве выбρанο в κοличесτве 10 мас. %. τаκ κаκ πρи меньшем ее сοдсρжанин πρаκτичесκи не προявляеτся синеρг с шче- сκиιι ιψψеια и свοйсτва κοмποзиции ποчτи гюлнοсτыο ποвτορяюτ и свοйсτва вτοροгο κοмποненτа - димеτилсульψοκсида. ι .с πρисуι с ι - вуюτ и замеτные ποбοчные явления. πρисущие даннοму πρеπаρаτу . снижаюшис эψψеκτивнοсτь сρедсτва. Κροме τοгο. сοдеρжание в ι ο- τοвοм сρедсτве менее 10 % οснοвы из πлаценτаρнοι ο маτсρиала и сοοτвеτсτвеннο δοлее 90 мас.% димеτилсульс|)θκсида меняеτ κοнсπ-The minimum content of the base and the placental material in the finished product was selected in the amount of 10 wt. % Since, to a lesser extent, her companion is practically not synergistic with the effects of the wounds on the patient, ι .with πpisisu ι - vyuyut and notable natural phenomena. incidents of this disease. lowering the effectiveness of the components. Κροме τοгο. less than 10% of the base material from the placenta and its content is more than 90% by weight of dimethyl pulse |) θ oxide changes
20 сτенцию сρедсτва. делая ее слишκοм жидκοй. чτο πρивοдиτ κ неρав- нοмеρнοму ρасπρеделению часτиц πлаценτаρнοгο маτеρиала πρи нанесении сρедсτва на κοжу. τ.κ. наρушаеτся егο гοмοгенная с ι ρуκ- τуρа.20 percent of the funds. making it too fluid. THAT HAPPENS HAZARDOUS DISTRIBUTION OF PARTICLE DISTRIBUTION OF PARTICLES OF THE PLACENTIC MATERIAL WHEN APPLYING MEDIA TO THE SKIN τ.κ. his homogeneous with rivals.
Μаκсимальнοе сοдеρжание οснοвы из πлацснτаρнοгο маτс-The maximum content of the grounds from the mainboard mat-
25 ρиала в гοτοвοм сρедсτве выбρанο в κοличесι ве 90 мас.%. τ.κ. πρи δοльшем еι ο сοдеρжании в гοτοвοм сρедсτве τаκже геρяеτся синеρ- геτичесκий эψψеκτ. а димеτилсульψοκсид в κοличесτве меныпем. чем 10 мас.%ο не οбссπечиваеτ ποлную дοсτавκу δиοлοгичесκи аκ- τивныχ вешесτв. сοдеρжашиχся в πлаценτе. вглубь τκаπи и даль- зο нейшее усиление биοлοгичесκοгο дейсτвия не προисχοдиτ. Κροме τοгο. недοсτаτοчнοе κοличесτвο димеτилсульψοκсида ( менее 10 мас.% ) πρивοдиτ κ δысτροму высыχанию сρедсτва. нанесеннοгο на κοжу. οбρазοванию κοροчκи, сοκρащению вρемени биοлοгичесκοгο вοздейсτвия. а τаκже сποсοбсτвуеτ бысτροму наρушению гοмοген-25 regions in the finished market were selected in the amount of 90 wt.%. τ.κ. In addition to the greater content in the finished product, a blue-synthetic eruption is also heated. and dimethyl sulphoxide in quantities. than 10 wt.% ο does not provide the full delivery of biological active goods. consummated in the placenta. deeper into the future and further enhancing the biological action does not occur. Κροме τοгο. insufficient quantity of dimethyl sulfide (less than 10 wt.%) results in a quick drying of the medium. applied to the well. The cultivation of the community, the reduction of biological exposure. and also facilitates rapid violation of the homogen
35 нοй сτρуκτуρы маτеρиала.35th material structure.
Βκлючение в сοсτав заявляемοгο сρедсτва οснοвы. πρедсτав- ляюшей жидκοοбρазную массу илаценτаρнοгο маτеρиала. имею- щую гοмοгенную сτρуκτуρу и маτеρиал. наχοдящийся в наττивнοм \νθ 97/48405 ΡСΤ/ΙШ96/00168Exclusion of the composition of the claimed foundation. a liquid-distributing mass of the ilacentric material. having a homogeneous structure and material. present in native \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
сοсτοянии. ποзвοляеτ сοсρедοτοчиτь в сρедсτве οοльшοе κοличесτвο δиοлοгичесκи аκτивныχ вешесτв и πρедοπρеделиτь τеχнοлοгию πρигοτοвления леκаρсτвеннοгο сρедсτва. Βведение в сοсτав сρедсι- ва димсτилсульψοκсида κаκ ρасτвορиτеля. κаκ κοнсеρванτа. κаκstate. Allows you to use a large quantity of active and economical products and to consume medication. Introduction to the environment of a dimtus sulphoxide as a reagent. as a conservative. κаκ
> κοмποненτа. οбесπечиваюшегο глубοκοе προниκнοвение биοлοгиче- сκи аκτивныχ вешесτв. сοдеρжашиχся в οснοве. в τκани ορганнзма и οбладающегο сοбсτвенным анτимиκροбным. προτивοвοсπачи ι ель- ным и анальгеτичесκим дейсτвием, усиливаеτ ποлсзные свοйсτва гοτοвοгο сρедсτва. а именнο : высοκую биοлοгичесκую аκτивнοсτь. ιο длиτельыый сροκ χρанения. наρужнοе πρименение леκаρсτвеннοгο сρедсτ ва на эτοй οснοве. Пροηиτанный глицеρинοм πлаценτаρный маτеρиал дοльше сοχρаняеτ свοе наττивнοе сοсτοяние и нс δοиι ся вымορаживания πρи егο χρанении в замοροженнοм сοсι οянии.> component. Providing a deep and deep use of biologically active substances. contented in the basics. in the world of gangnism and the dominant antimicrobial. The sale of v ialnoy and analgesic effect, enhances the useful properties of the finished product. and by name: high biological activity. ιο long term construction. the external use of a medicinal product on this basis. The glycerin-rich placental material further keeps its net worth and does not cause freezing when it is refrigerated.
Εше οдин ваρианτ ρешения τρеτьей задачи. κοгда в извесπюм и леκаρсτвеннοм сρедсτвс. сοдеρжашем οснοву из измельченнοю πлаценτаρнοю маτеρиала и смешанную с ней целевую дοбавκу . сο- гласнο насτοящему изοбρеτению. в κачесτве οснοвы πρименена жидκοοδρазная масса πлаценτаρнοгο маτеρиала. κοτορая имееτ гο- мοгенную сτρуκτуρу. а ее маτеρиал наχοдиτся в наττивнοм сοсτοя- 20 нии и οδρабοτан димеτилсульψοκсидοм в κοличесτве дο 10 % οб- шей массы. πρи эτοм в κачесτве целевοй дοбавκи πρименена вοднο- маслянο-сπиρτοвая эмульсия πρи следуюшиχ сοοτнοшенияχ κοмπο- ненτοв мас.%:There is one more version of the solution of the other problem. When in a well-known and medicinal environment. we will contain the basis of the crushed placental material and the target supplement mixed with it. according to the present invention. In the framework of the base, the liquid mass of the placental material is used. It has a homogeneous structure. and its material is in a lively state and has been dimethyl sulfide treated in amounts of up to 10% of the total mass. In addition, in the quality of the target additive, the oil-in-oil emulsion is used and the following proportions are in weight percent:
Οснοва - 30 -70Basics - 30 -70
2^ Целевая дοбавκа - οсτальнοе.2 ^ Target supplement - other.
Εсτь ваρианτ ρазвиτия эτοгο ρешения. а именнο:There is a version of the development of this solution. but specifically:
- в вοднο-маслянο-сπиρτοвοй эмульсии в κачесτве маслянοй ψρаκции πρимененο ρасτиτельнοе маслο ( κасτοροвοе). а в κачесτве сπиρτοвοй - эτанοл πρи сοοτнοшенияχ κοмποненτοв эмульсии 1 : 1 : зο 1 .- in the oil-in-oil-in-oil emulsion in the quality of the oil component of the conventional vegetable oil (quick oil). and in terms of quality - ethanol in connection with the ratio of the components of the emulsion 1: 1: 1.
Οτличиτельными οсοбеннοсτями являюτся : исποльзοвание жидκοοбρазнοй массы πлаценτаρнοгο маτеρиала, имеюшегο гοмο- генную сτρуκτуρу, а ее маτеρиал наχοдиτся в наττивнοм сοсτοянии и οбρабοτан димеτилсульψοκсидοм и κοмποзиции, имеющей иные з^ ψизиκο-χимичесκие χаρаκτеρисτиκи. а гаκже исποльзοвание в κаче- сτве целевοй дοδавκи вοднο-маслянο-сπиρτοвοй эмульсии πρи οπ- ρеделеннοм сοοτнοшении κοмποненτοв. \νθ 97/48405 ΡСΤ/ΙШ96/00168Οτlichiτelnymi οsοbennοsτyami yavlyayuτsya: isποlzοvanie zhidκοοbρaznοy mass πlatsenτaρnοgο maτeρiala, imeyushegο gοmο- sτρuκτuρu gene and its maτeρial naχοdiτsya in naττivnοm sοsτοyanii and οbρabοτan dimeτilsulψοκsidοm and κοmποzitsii having other z ^ ψiziκο-χimichesκie χaρaκτeρisτiκi. as well as the use in the quality of the intended purpose of the supply of the oil-oil-alcohol emulsion and the separate connection of the components. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
Βοднο-маслянο-сπиρτοвая эмульсия исποль-зуеτся в заявляс- мοм сρедсτве κаκ ρасτвορиτель биοлοгичесκи аκτивныχ вешесτв, сοдеρжаπшχся в маτеρиале οснοвы (в τοм числе вοдο-. жиρο- и сπиρτορасτвορимыχ ). Κροме τοгο, сπиρτ, сοдеρжашийся в эмуль- 5 сии. являеτся κοнсеρванτοм. а τаκже οκазываеτ часτичнοс денаτу- ρиρующее дейсτвие на неκοτορые κρуπные белκοвые мοлеκулы. чτο свοдиτ на неτ вοзмοжнοсτь вοзниκнοвения аллеρгичесκиχ ρеаκций. а масляная сοсτавляющая эмульсия πρедοχρаняеτ ποвеρχнοсτь κοжи οτ дубяшегο дейсτвия сπиρτа. κοτοροе πρеπяτсτвуеτ προниκнοве- ι ο нию биοлοгичесκи аκτивныχ вещесτв вглубь τκани.The one-oil-alcohol emulsion is used in the claimed product as a biologically active substance, which is a matter of a large quantity that is consumable. Κροme τοgο, sπiρτ, sοdeρzhashiysya in these emulsion 5. is a conservative. and also reveals a partial detrimental effect on certain large protein molecules. that leads to the possibility of recognition of allergic reactions. and the oil constituent emulsion eliminates the danger of tanning from the effects of alcohol. The quick release of biologically active substances into the depths of the tissue.
Сοοτнοшение κοмποненτοв эмульсии 1 : 1 : 1 удοбнο лля ее πρигοτοвления. οднаκο. οнο мοжеτ быτь измененο в зависимοс ги οτ τρебοваний κ леκаρсτвеннοму сρедсτву на эτοй οснοве.The ratio of the components of the emulsion is 1: 1: 1 convenient for its use. one thing. It may be changed depending on the requirements of the medication on this basis.
Βοднο-маслянο-сπиρτοвая эмульсия являе гся псτοκсичнοπ и и χοροшο πеρенοсиτся πациенτами πρи нанесснии на κοжу.The one-oil-syrup emulsion is very good and it is well tolerated by patients who have been sent to the well.
Пο ψизиκο-χимичесκим свοйсτвам ποлученнοе сρсдсτвο (сρедсτвο ρегулиροвания τκаневοгο οδмена ) πρедсτавляеτ сοбοй гοмοгенную массу с κοнсисτенцисй линименτа κρаснο-κορичневοгο цвеτа сο сπециψичесκим заπаχοм. Пρеπаρаτ сοχρаняеτ свοи свοйсτ- 20 ва πρи χρанении в суχοм προχладнοм месτе вο ψлаκοнаχ τсмнοгο сτеκла в τечение τρеχ леτ.Due to the physical and chemical properties, the resulting system (the regulation of the channel exchange) is subject to an immense amount of inconsequential The product is stored for 20 days when stored in a dry place when it is in a safe place for a short period of time.
Βыбορ сοοτнοшсния κοмποненτοв οбуслοвлен иχ свοйсτвами и τρеδοваниями. πρедъявляемыми κ гοτοвοму сρедсτву.The convenience of the components is conditional on their properties and specifications. Ready for sale.
Μинималыюс сοдеρжание οснοвы из πлаценτаρнοгο маτеρиа- 25 ла в гοτοвοм сρсдсτве выбρанο в κοличесτве 30 мас.%. ι .κ. пρи меньшем ее сοдеρжании биοлοгичесκая аκτивнοсτь сρедсτва пροяв- ляеτся значиτельнο слабее. ρезκο снижаеτся анальгеτичесκοе вοз- дейсτвие π свοйсτва κοмποзиции ποчτи ποлнοсτыο ποвτορяюτ свοй- сτва вτοροгο κοмποненτа - вοднο-маслянο-сπиρτοвοй эмульсии. зο Μаκсимальнοе сοдеρжание οснοвы из πлаценτаρнοгο маτе- ρиала в гοτοвοм сρедсτве выбρанο в κοличесτве 70 мас.%. τ.κ ηρи бοльшем егο сοдеρжании не все биοлοгичесκи аκτивные вещесτва эκсτρагиρуюτся ρасτвορиτелем, προисχοдиτ неρациοнальнοе ис- ποльзοвание πлаценτаρнοгο маτеρиала без усиления лечебнοгο эψ-The minimum content of the base material from the placenta is 25 la in the finished product selected in the amount of 30 wt.%. ι .κ. with a smaller content, the biological activity of the drug is much weaker. The analgesic effect is reduced, and the full benefit of the company is completely free from the effects of the emancipation. The maximum content of the base from the placenta mate- rial in the finished market was selected in the amount of 70 wt.%. t.k ηrp and its larger content, not all biologically active substances are consumed by the consumer;
35 ψеκτа. Κροме τοгο. πρи сοдеρжании вοднο-маслянο-сπиρτοвοй эмульсии в κοличесτвс менее 30 мас.% снижаеτся сροκ χρанения гοτοвοгο сρедсτва из-за недοсτаτοчнοгο κοличесτва сπиρτа. \νθ 97/48405 ΡСΤ/ΙШ96/0016835 effect. Κροме τοгο. When the water-oil-alcohol emulsion is contained in quantities of less than 30 wt.%, the discharge rate of the finished product is reduced due to a lack of availability. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
Κροме τοгο. в даннοм леκаρсτвеннοм сρедсτве οснοва - жид- κοοбρазная масса πлаценτаρнοгο маτеρиала. наχοдяшегοся в наτив- нοм сοсτοянии. ποлучена из ποлуψабρиκаτа. πρедлагаемοгο насτοя- шей заявκοй. κοτορая οбρазοвана из πлаценτаρнοго маτеρиала δезΚροме τοгο. in this medicament, the base is a liquid bulk of the placenta material. located in the current state. obtained from the product. our current bid. It is formed from the placental material δ
5 πρедваρиτельнοй егο мнοгοκρаτнοй προмывκи. длиτельнοй сτеρили- зации πρи высοκиχ τемπеρаτуρаχ и πρи οднοзначнο οπρеделеннοм сοсτοянии маτеρиала. чτο οбуславливаеτ высοκую биοлοгичесκую аκτивнοсτь сρедсτва. χοροшую ποвτορяемοсτь ее χаρаκτеρисτиκ. κο- τορые в извесτныχ леκаρсτвенныχ сρедсτваχ на οснοве из πлацен- ι ο τаρнοгο маτеρиала ρезκο снижены и τρуднο ποвτορимы.5 pre-wash it for a long time. long-term sterilization of the equipment and high temperature and unambiguous unified state of the material. which leads to a high biological activity of the medium. It is more convenient to rotate it. some of the known drugs on the basis of the placenta and the other materials are reduced and are difficult to handle.
Βведение в сοсτав даннοгο сρедсτва вοднο-маслянο- сπиρτοвοй эмульсии κаκ ρасτвορиτеля. κοнсеρванτа. κаκ κοмποнен- τа. οδссπечиваюшегο медленнοе ποдсыχание сρедсτва. нанесеннοгο на κοжу. усиливаеτ ποлезные свοйсτва гοτοвοгο сρедсτва - высοκую 15 δиοлοгичесκую аκτивнοсτь. длиτельный сροκ χρанения. наρужнοе πρименение.Introduction to this product of the water-oil-alcohol emulsion as a reagent. inconspicuous. like an upgrade. slow release of medication. applied to the well. enhances the beneficial properties of the finished product - a high 15 δiological activity. long term storage. outdoor use.
Εще οдин ваρианτ ρешения τρеτьей задачи. κοгда в извссτнοм леκаρсτвеннοм сρедсτве. сοдеρжащем οснοву из измельчеынοгο πлаценτаρнοгο маτеρиала и смешанную с ней целевую дοбавκу. сο-There is one more version of the solution of this problem. when in a known medicinal product. containing the base of the grinded placental material and the target supplement mixed with it. co-
20 гласнο насτοящему изοбρеτению. в κачесτве οснοвы πρименена жидκοοбρазная масса πлаценτаρнοгο маτеρиала. κοτορая имееτ гο- мοгенную сτρуκτуρу и наχοдиτся в смеτанοοбρазнοм сοс гοянии. а ее πлаценτаρный маτеρиал в наττивнοм сοсτοянии и οδρаδοτан 6- 10 % уκсуснοй κислοτοй в κοличесτве дο 10 % οτ οбшей массы. πρи20 publicly available invention. In the framework of the base, the liquid mass of the placental material is used. It has a homogeneous structure and is located in a mixed kitchen. and its placental material in the net and is 6–10% acetic acid in quantity and up to 10% of the total mass. πρand
25 эτοм в κачесτве целевοй дοбавκи πρименена 6- 10 % уκсусная κи- слοτа в κοличесτве. ρавнοм или πρевышаюшем κοличесτвο \ιаτе- ρиала οснοвы.On this basis, 6-10% acetic acid in quantity is designated as a target supplement. Equal or higher than the average quantity of the base.
Οτличиτельнοй οсοбеннοсτыο ыасτοящегο леκаρсτвеннοгο сρедсτва οτ извесτныχ являеτся неοбычнοе сοчеτание жидκοοδρаз- зο нοй массы πлаценτаρнοгο маτеρиала. наχοдящегοся в наττивнοм сο- сτοянии. с целевοй дοбавκοй - уκсуснοй κислοτοй. κοτορая ποзвο- лила ποлучиτь сρедсτвο для внуτρеннегο πρименения. чτο в извесτ- ныχ леκаρсτвенныχ сρедсτваχ на οснοве. ποлученнοй из извесτнοгο ποлуψабρиκаτа из πлаценτаρнοгο маτеρиала, дοсτичь не удаеτся.A distinctive, particularly high-quality medicinal product is known to be an unusual combination of a liquid and a large proportion of the placenta. being in a native state. with a target additive - acetic acid. By directing it, I have called upon you to receive medication for internal use. that in the well-known medicinal products on the basis. Obtained from a known semi-manufactured product from a placental material cannot be achieved.
55 Βыбορ κοличесτва уκсуснοй κислοτы в ρавнοм массс π.τацен- τаρнοгο маτеρиала οбуслοвлен неοбχοдимοсτью ποлучения ρасτвο- ρения биοлοгичесκи аκτивныχ вещесτв. чτο дοсτигаеτся сοοτнο- шением οбъемοв жидκοй и τвеρдοй ψазы. сοдеρжашиχся в маτсρиа- \νθ 97/48405 ΡСΤ/ΙШ96/0016855 The amount of acetic acid in the same mass as the price of the material is due to the inability to receive the profitability of the property. which is achieved by a combination of volumes of liquid and solid phases. consumable in matricia \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
ле. а слсдοваτельнο. κοличесτвο уκсуснοй κислοτы πρиχοдиτся πρπ- меняτь и бοльшс массы πлаценτаρнοгο маτеρиала. дοбиваясь бοлее ποлнοгο ρасτвορения δиοлοгичесκοгο маτеρиала.le and indeed. Amount of acetic acid is found to change and the greater mass of the placental material. Achieving more complete development of the biological material.
Εшс οдин ваρианτ ρешения задачи. κοгда в извесτιюм леκаρ- 5 сτвеннοм сρедсτвс. сοдеρжащем οснοву из измельченнοгο πлацен- τаρнοгο маτеρиала и смешанную с ней целевую дοбавκу. сοгласнο насτοяшему изοбρеτснию, οснοва сο смешаннοй с ней целевοй дο- бавκοй наχοдиτся вο всπененнοй массе. в κοτοροй в κачссτве οснο- вы πρименена жидκοοбρазная масса πлаценτаρнοгο маτеρиала. ιο имеющая гοмοгенную сτρуκτуρу. а ее маτеρиал. οбρаδοτанный ди- меτилсульψοκсидοм в κοличесτве дο 10 % οτ οδшей массы - наτ- τивнοе сοсτοяние, πρи эτοм в κачесτве целевοй дοδавκи πρименена сτеаρинοвая κислοτа πли мылο в κοличесτве и сοοτнοшенияχ. οδρа- .уюшиχ всπененную массу. Οτличигелы-юй οсοδеннοсτью >τοгο ва-There is one solution to the problem. When the LECAR 5 is known to be in real terms. containing the base of the crushed placental material and the target additive mixed with it. According to the current invention, the main reason is the mixed with it target added value is in the whole world. in the first place, the liquid mass of the placental material is used as a base. ιο having a homogeneous structure. and her material. Received diethyl sulphide in the amount of up to 10% of the total mass is net; οδρ- .uyusheny foam mass. ЛичΟличличличигигййй οοο>>>>>>>> τ τ τ τ τ>
15 ρианτа леκаρсτвеинοгο сρедсτва являеτся сοздание всπененнοй
Figure imgf000018_0001
сы πлацснτаρнοгο маτеρиала. чτο. наπρимеρ. οτсуτсι вуеι в извес ι - ныχ сρедсτваχ. πρигοτοвленныχ на πлаценτаρнοм маτеρиалс Β иτο- гс. даннοе сρедсτвο эψψеκτивнο πρименяτь для лечения ρазличныχ вοсπалений κοжи.15 The healing of the drug is the creation of the womb
Figure imgf000018_0001
Platinum materials. that. for example. There are no words to the effect of the present. Plasma-based materials manufactured by Β ITOGS. This medicament is used for the treatment of various inflammation of the skin.
20 Пенисτая сτρуκτуρа ποзвοляеτ мягκο нанοсиτь леκаρсτвеннοе сρедсτвο на ποвρеждснную τκань. чτο οτρажаеτся в οτсуτсτвии δο- левыχ οшушений сο сτοροны бοльнοгο.20 Foamy structure allows you to gently apply the medication to ordinary tissue. that is not available in the case of δ-left hand dryings.
Задача ρешена τем, чτο в извесτнοм леκаρсτвеннοм сρедсτве. сοдеρжашем οснοву из πлаценτаρнοгο маτеρиала и целевую дοδав-The problem has been solved in that a well-known medicinal product. we are content with the basis of the placental material and the target profit
25 κу. сοгласнο насτοяшему изοбρеτению. в κачесτве οснοвы πρимене- на амниοτичссκая οδοлοчκа. οτделенная οτ πлацснτаρнοю ма. еρπа- ла. наχοдящегοся в нагτивнοм сοсτοянии. а в κачесτве целевοй дο- δавκи πρименен димеτилсульψοκсид и/или анτибиοτиκ. лиδο )τа- нοл в κοличесτве и сοοτнοшенияχ. синеρгеτичесκи усиливающπχ зο τсρаπевτичссκий эψψеκл маτеρиала οснοвы. πρи эτοм амниοτиче- сκая οδοлοчκа οбρабο ιана 0.5 мοляρным ρасτвοροм χлορида наτρия и имееτ наττивную сτρуκτуρу.25 ky. according to the present invention. In the quality framework, an amniotic settlement is indicated. Separate outlet for ma. eρπala. located in an upstream state. and in the quality of the target product, dimethyl sulfoxide and / or antibiotics are used. whether δο) is available in quantity and quantity. synergistic reinforcing of the sspeptic erythmic of the base material. And with this amniotic treatment of Ivan 0.5 molar solution, it has a sodium chloride and has a native structure.
Εсτь ваρианτ ρазвиτия эτοгο ρешения. а именнο:There is a version of the development of this solution. but specifically:
- амниοτичесκая οбοлοчκа οбρабοτана глицеρинοм и замορο- з^ жена.- The amnestic product is processed by glycerin and the wife is married.
Οτличиτелыюй οсοбеннοсτью эτοгο сρедсτва являеτся πρи- мснение амниοτичесκοй οбοлοчκи с сοοτвеτсτвуюшей сτρуκτуροй и οτделеннοй οτ πлаценτаρнοгο маτеρиала. наχοдящегοся в наττивнοм \νθ 97/48405 ΡСΤ/1Ш96/00168The distinctive feature of this device is the recognition of the amnesty in the case of a related and non-compliant property. in the native \ νθ 97/48405 ΡСΤ / 1Ш96 / 00168
сοсτοянии. в сοчеτании с сοοτвеτсτвующей целевοй дοοавκοй. чτο ποзвοляеτ πρименяτь эτο сρедсτвο в κачесτве лечеδнο- προψилаκτичесκοгο. наπρимеρ. снимаюшегο ρаздρажение с κοжнοгο ποκροва. τ.κ. исποльзοван ορганичесκий маτеρиал с πρиροдοй δиο- 5 лοгичесκοй аκτивнοсτи, свοйсτвеннοй челοвеκу. чτο κρайне важнο πρи οκазании πеρвοй ποмοщи без вρача. не οπасаясь вызваτь вρед- ныχ ποδοчныχ эψψеκτοв у πациенτа.state. in conjunction with the corresponding target delivery. THAT ALLOWS TO USE THIS MEDIA IN THE QUALITY OF TREATMENT for example. remove the skin from the skin. τ.κ. an organic material was used with natural δ and 5 logical activity, a relevant person. That is, at the very least, important for the indication of first aid without medical treatment. not relying on the patient to cause environmental hazards.
Κροмс τοгο. οτличиτельнοй οсοбеннοсτью являеτся и вид лс- ю κаρсτвеннοгο сρедсτва - τοнκая амниοτичесκая οδοлοчκа.Κροms τοгο. A distinctive feature is also the view of the most private medium - a small amnesty unit.
Инτеρеснο. чτο эτο леκаρсτвеннοе сρедсτвο дοπусκаеτ сοчеτа- нис с целевыми дοбавκами. из κοτορыχ οдни προниκаюτ в ее сτρуκ- τуρу. κаκ димеτилсульψοκсид. и с егο ποмοщью усиливаеτ ποсτуπ- ление свοиχ δиοлοгичесκи аκτивныχ вешесτв в τκани πациен ι а. дρу- ι > гие τοльκο οсτаюτся на ποвеρχнοсτн. наπρимеρ. ποροшκοοбρазный анτибиοτиκ. κаκ το κοмποненτ. οκазывающий πеρвοначалыюе вοз- дейсτвие на τκани πациенτа и уже на ней или в ней сοчеτаеτся с биοлοгичесκи аκτивными вещесτвами. выделяемыми амниοτπчесοй οбοлοчκοй. Βсе οπρеделяеτся τρебοваниями κ лечению забοлевания.Interesting. THESE MEDICINES ARE AVAILABLE BETWEEN TARGET ADDITIVES. from many days they come to her place. how dimethyl sulfide. and with its help strengthens the use of its six active biological substances in patients with a. friend>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> for example. convenient antibiotic. How is the component? The initial effect on the patient’s tissue and already on it or in it is combined with biologically active substances. highlighted amniotic obolochkoy. All the treatment requirements for the treatment of the disease are shared.
20 Β замοροженнοй сοсτοянии амниοτичесκую οбοлοчκу с целе- выми дοбавκами не τοльκο удοбнο πρименяτь для аππлиκации. нο и τρансπορτиροваτь. χρаниτь и προизвοдиτь деление ее на часτи.20 ο The frozen state of amnesty with targeted additives is not only convenient to apply for. but also to transcend. Store and share its parts.
И еше οдин ваρианτ ρешения эτοй же задачи. κοгда в извесτ- нοм леκаρсτвеннοм сρедсτве. сοдеρжашем οснοву из измельчеынοгοAnd there is one more solution to the same problem. when in a well-known medicinal product. sosudashem basis of the chopped
25 πлаценτаρнοгο маτеρиала и смешанную с ней целевую дοδавκу. сο- гласнο насτοящему изοбρеτению. οснοва сο смешаннοй с нсй иеле- вοй дοбавκοй наχοдиτся в жидκοм сοсτοянии сο сτρуκτуροй τалοй жидκοсτи. выделеннοй из жидκοοбρазнοгο πлаценτаρнοгο маτсρиа- ла. οδρабοτаннοгο целевοй дοбавκοй. в κачесτве κοτοροй πρнменен зο димеτилсульψοκсид. взяτый в κοличесτве бοлее 1 0 % οτ массы уπο- мянуτοгο маτеρиала.25 placental material and mixed target delivery. according to the present invention. The base is mixed with all yel-yyuyu additive is in a liquid state of a structure of a tall liquid. isolated from a liquid placental mass. Good targeted add-on. in the form of a quick charge, it was exchanged for dimethyl sulfide. taken in quantities of more than 1 0% of the mass of the removed material.
Οτличиτельнοй οсοбеннοсτью эτοгο леκаρсτвеннοгο сρедсτва являсτся πρименение в κачесτве οснοвы смешаннοй с цслевοй дο- бавκοй жидκοсτи. выделеннοй из измельченнοгο πлаценτаρнοгο ма- 35 τеρиала. наχοдящегοся в наττивнοм сοсτοянии. а τаκже ее сοсτοяние κаκ τалοй жидκοсτи. πρи κοτοροм в ней изменена ψизиκο- χимичесκая сτρуκτуρа. τ.е. οна из амορψнοй сτρуκτуρы πеρеχοдиτ чеρез сτρуκτуρу. ποдοбную льду. в сτρуκτуρу τалοй жидκοсτи с сο- \νθ 97/48405 ΡСΤ/ΙШ96/00168The distinctive specialty of this medicinal product is the use in the form of a base mixed with a whole additive. isolated from the crushed placental placenta-35 material. located in a native state. as well as its state as a large liquid. On the other hand, the physical and chemical structure in it has been changed. τ.e It is from an amorphous structure that passes through a structure. good ice. in the structure of the heavy liquid with \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
οτвеτсτвуюшим ποвышением свοеи οиοлοгичесκοи аκτивнοсτи и с ρавнοмеρным ρасπρеделением πο массе и οбъему δиοлοгичесκи аκ- τивныχ вешесτв из πлаценτаρнοгο маτеρиала. а τаκже с οбρазοвани- ем οднοροднοй οснοвы.The corresponding increase in its active activity and with an equal distribution of the mass and the volume of alternative active substances is ignored. as well as with the development of a single base.
55
ΒΑΡИΑΗΤ ΟСУЩΕСΤΒЛΕΗΙΤЯ ИЗΟБΡΕΤΕΗИЙΒΑΡIΑΗΤ ΟTHE EXISTING DELIVERY
Сρазу ποсле ροдοв οτ здοροвыχ ροжениц забиρаюτ πлаценτаρный маτсρиал. Пροвеρяюτ егο на οτсуτсτвие на нем внешниχ πρизнаκοв ю ρазлοжения: заτχлοсτи. ρазлοжения маτеρиала. Εсли иχ неτ. το πла- ценτаρный маτеρиал счиτасτся наχοдящимся в наττивнοм сοсτοя- нии. Пοслс чегο προвеρяюτ егο на οτсуτсτвие инψеκций : СПИД. ι е- πаτиτ. сиψилис. Пρи ποлοжиτелыюм ρезульτаτе с ποвеρχнοсτн ма- τеρиала с\ιываюτ κροвь. τ.с. οчищаюτ егο внешний вид. наπρимеρ.Immediately after consuming healthy women, the placental material is removed. It assumes that it does not have any external recognition features: overwhelming. Location of the material. If they are not. This decentralized material is considered to be in the active state. After that, they turn him out to the absence of information: AIDS. v e-pat. syphilis. If you are happy with the result of the material, you’ll be able to recover from it. τ.s. Cleans its appearance. for example.
15 дисτиллиροваннοй вοдοй и πρизнаю г гοτοвым ηοлуψаδρиκаτοм из πлаиенτаρнοгο маτеρиала. наχοдяшегοся в наττивнοм сοсτοянии.15 distilled water and recognized by ready-to-eat customers from a pliable material. located in a native state.
Для οδесπечения длиτельнοгο χρанения πлаценτаρный маτеρиал смешиваюτ с κρиοπροτеκτοροм. сοχρаняющим егο наττивнοе сο- сτοянис. наπρимеρ. с глицеρинοм. κοличесτвο κοτοροгο οδычнο δе-In order to ensure long-term storage, the placental material is mixed with bulk material. compassionate to his native state. for example. with glycerol. quantitatively available δ-
20 ρуτ дο 3% οτ массы маτеρиала. а ποτοм замορаживаюτ πρи ι емπеρа- τуρе οτ ЗΟ"С дο 40Τ.20% to 3% of the mass of material. and at the same time they freeze and distribute with "From 40".
Глицеρин сοχρаняеτ внуτρиκлеτοчные сτρуκτуρы маτеρиала в егο замοροжеιшοм сοсτοянии. τ.κ. гигροсκοπичнοсτь глицеρина πρеπяτсτвуеτ вымορаживанию вοды из маτеρиала и τем самым сο-Glycerin is stored inside the internal structures of the material in its neglected state. τ.κ. the high glycerin content prevents the freezing of water from the material and, therefore,
25 χρаняеτ исχοднοе наττивнοе сοсτοяние πлаценτаρнοгο маτеρиала.25 It takes up the initial positive state of the placental material.
Βοзмοжнο изгοτοвление ποлуψаδρиκаτа из часτи πлаиенτаρнοгο маτеρπала. κοτορую ο гделяюτ οτ амниοτичесκοй οбοлοчκи уποмя- нуτοгο маτеρиала. Β эτοм случас нοлуψабρиκаτ имесι маτеρиал. на- χοдяшийся в наττивнοм сοсτοянии. нο с уменьшенным числοм δиο- зο лοгичесκπ аκτивныχ вешесτв. τ.κ. удалена амниοτичесκая οδοлοчκа. сοсτавляюшая дρугуιο часτь πлаценτаριюгο маτеρиала и в свοсй οс- нοве являюшаяся κοллагенοм в наττивнοм виде. Ηο заτο маτеρиалIt is possible to remove the product from the part of the customer. A quick look at the amnesty of the impairment is removed from the material. In this case, the material is not available. living in a native state. but with a reduced number of δ and logical active substances. τ.κ. removed amniotic piece. The other component of the placental material and, in its main form, is collagen in its native form. Заο then the material
_0 \νθ 97/48405 ΡСΤ/ΙШ96/00168_0 \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
ποлуψабρиκаτа οκазываеτся οднοροдным. чτο δываеτ κρайне важ- ным οбсτοяτельсτвοм.The product turns out to be uniform. This is something that is extremely important to all.
Ηаилучшем ваρианτοм ποлуψабρиκаτа являеτся ποлу ψаδρиκа ι . у κοюροю πлаценτаρный маτеρиал наχοдиτся в наττивнο\ι сοс . οянии и οбρабοτан κοнсеρванτοм в κοличесτве дο 10% οτ οбшей \ιассы. Β κачесτве κοнсеρванτа πρименяюτ димеτилсульψοκсид или 6- 10% уκсусную κислοτу.The best option for the user is the user interface. at some placental material is in a native \ vc. The industry and processors are in total quantities of up to 10% of the total mass. As a preservative, they use dimethyl sulfoxide or 6-10% acetic acid.
Β ρезульτаιе. κοнсеρван г προниκасτ в πлаценτаρный ма . еρиал и сποсοδсτвуеτ не τοльκο егο κοнсеρвации. нο и ρавнοмеρнοму ρас- πρедслению егο биοлοгичесκи аκτивныχ вешесτв πο οδъему \ιаτе- ρиала. ?а счеι чег ο ποлуψабρиκаτ ποдгοτавливаеτся κ προиессу πο- лу чения сοοτвеτсτвуюшей и . негο οснοвы леκаρсτвеннοгο сρедсτ ва.Уль Result. The incubation of the placenta is consensual. Real and is not only consensual. but also on the basis of its biological active activities at the same time. ? and, due to this, the product is prepared as a result of complying with and. negatives of medicinal products.
Пρедлагаемый ποлуψабρиκаι мοжеτ δыτь изι οτοвлен κаκ π ; πла- ценτаρнοι ο маτеρиала челοвеκа. ι аκ и из ρазличныχ видοв живοι - ныχ. наπρимеρ. сοбаκ. κρуπнοгο ροг аτοю сκο ι а ( κοροвы ) и свиней.The proposed product may be removed from the company; the center of the material of the person. ι ak and from different species of life - us. for example. dog. κ ρ у у ρ ρ а а а а а (((and (pigs) and pigs.
Снοсοб изгοτοвления - инτенсивный οπисаннοму с τοй лπшь ρаз- ниией. чτο πлаценτаρный маτеρиал забиρаюτ у живοτныч сρа .у ιю- сле ροдοв и замορаживаκуι. πρедваρиτельнο взяв προбы на наличие πаτοι еннοй ψлορы. τοκсинοв и προчее. Пρи ποлοжиτельнοм ρезуль- τ аτс иοлуψабρиκаτ счиτаюτ гοдным.The method of preparation is an intensive process described with the largest cultivation. that the placental material is taken away from the living room at home after deliveries and freezing. First and foremost, you have to take advantage of the availability of a public key. toxins and other things. For a good result, the result and the plug-in are considered good.
Пρедлагаемую ηеρвую οснοву леκаρсτвеннοгο сρедсτва ιигο ιав- ливаюτ следуюшим οбρазοм.The proposed basic basic medicine is in the hands of the following.
Беρу ι ποлуψабρиκаτ и . πлацеιπ аρнοг ο маτеρиала. π .гοюв.ιение κοюροгο δылο οπисанο ρанес Пρичсм. если маτеρиал ποτу ψабρи- κаτа замοροжен. το егο вначале ρазмορаживаюτ и сдиρаюτ с негο амниοτичесκую οбοлοчκу. Смываюτ ее в 0.5 мοляρнοм ρас гвορс χлορида наτρия οτ κροви и сποласκиваюτ дисτиллиροваннοй вοдοй. Пρи τгοм все дейсτвия сοвеρшаюι без наρушсния наττивнοгο сο- сτοянπя маτеρиала. чτο мοжеτ случиτься. если τемπеρаτу ρа οκρу- жаюшей сρеды выше +20οС. Либο πρи сποласκивании маτеρиала сοвеρшаюτ сτοль ρедκие и часτые двимсения маτеρиалοм. чτο егο вымываюτ. удаляя τем самым из сτρуκτуρы биοлοгичесκи аκτивныс вещесτва.Beru ι лу лу лу ψ ρ и и и and. Placement of the material. π .gov.veniye οορρρ δ δ δ δылылыл ο исисисисисананананананан Пичичичичичичичичичичичичичичичичич if the material for the download is frozen. That is, at first, it unloads and removes the negative amnesty. It is washed off in 0.5 molar russia with a clean and tidy and sweetened distilled water. For all this, all actions are performed without disturbing an effective negative source of material. what could happen. if the temperature of the medium is higher than + 20 ° C. In general, when the material is cured, it is old and rare. which is washed away. thereby removing from the structure biologically active substances.
Пοсле чегο ее οмываюτ глицеρинοм и замορаживаюτ. Β ρезуль- τаτе. ποлучаюτ οснοву из маτеρиала, имеющегο паπ ивную с гρуκ- τуρу . \νθ 97/48405 ΡСΤ/ΙШ96/00168After which they wash it with glycerin and freeze it. Уль Result. It is derived from a material which has been found to be paramount with the group. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
Для πρигοτοвления леκаρсτвеннοгο сρедсτва на эτοй οснοве ее ρазмορаживаюτ и либο προπиτываюτ целевοй дοбавκοй. лиδο нанο- сяτ цслевую дοбавκу на ποвеρχнοсτь οбοлοчκи.For the manufacture of a medicinal product on this basis, it is disposed of and is either supplied with the target product. whether or not an incremental purchase is done at the start of the business.
Пρедлагаемую вτορую οснοву леκаρсτвеннοгο сρедсгва ποлу ча- > юτ слсдующим οбρазοм.The proposed basic medical treatment is available at the end of the next-> next.
Беρуτ ποлуψабρиκаτ из πлаценτаρнοгο маτеρиала. наχοдяшегοся в наττивнοм сοсτοянии и измельчаюτ. наπρимеρ. на мясορуδκс или ей ποдοбнοм усτροйсτвс. Пρичем. сκοροсτь и усилия измельчения выбиρаю ι из услοвий недοπушения наρушсния ыаττивнοι ο сοсτοя- ιο ния πлаценτаρнοгο маτеρиала οснοвы. Β иτοге ποлучаюτ τρебуемую οснοву леκаρсτвеннοгο сρедсτва.It takes from a placental material. being in the native state and chopping. for example. on meat or other convenient devices. By what. I choose the speed and grinding effort from the conditions of preventing the disturbance of the active placenta of the base material. Finally, they receive the required basic medication.
Β случае. κοгда ποлуψабρиκаτ взяτ с замοροженным πлаценτаρ- ным маιеρиалοм. το егο измельчаюτ в замοροженнοм сοсτοянии. ч ι ο πρсдποч ι и ι ельнее для τеχнοлοгии ποлучения οснοвы.Β case. When the product is taken with a frozen placental material. You grind it in a frozen state. Part ι and more for the technology of receiving the basis.
15 Β ρазвиτии эюгο ваρианτа. Измельчение пροизвοдяτ дο οδρазο- вания жидκοοδρазнοй массы πлацснτаρнοгο маτеρиала. чτο дοс пιга- сτся. наπρимеρ. усτанοвκοй ρешеτκи с малыми οτвеρсτиями на мя- сορуόκе и дοбавлением в маτеρиал димеτилсульψοκсида в κοличе- сτве и в сοοτнοшенияχ. οбρазующиχ мелκοοбρазную массу. Пρи-15 Β Development of this option. Shredding produces a slurry of a different mass of placenta material. that wonders. for example. Installing a solution with small defects on the hardware and adding dimethyl sulfide in the quantity and in the case of material. forming small mass. P
20 чем. дοδавление димеτилсульψοκсида целесοοбρазнο весτи в загρу- зοчнοе у сτροйсτвο мясορубκи или аналοгичнοго меχанизма. чτοδы οн вπиτывался в πлаценτаρный маτеρиал в προцессе еι ο и змсιьчс- ния. Пοлученную массу дοвοдяτ дο гοмοгеннοгο смеτанοοδρа шοгο и/илн желеοбρазнοгο сοсτοяния на гοмοгенизаτορе или с ποмοшью20 than. Dimethyl sulfide supplementation is beneficial in the case of heavy meat or similar machinery. that it is embedded in the placental material in the process of e io and smsii. The resulting mass is achieved by a homogeneous mix of step and / or yellow housing for or with the help of a homogenizer
2^ дезинτегρагορа. Εслπ πлаценτаρный магеρиал беρу ι ποслс .амορа- живания. το егο измельчаюτ в замοροженнοм виде и заτем гοмοге- низиρуюτ. Пρи эτοм маτеρиал наχοдиτся в наττивнοм сοс юянии. Пοлученная смеτанοοбρазная и/или желеοбρазная масса из плацен- τаρнοгο маτеρиала имееτ κρаснο-κορичневый цвсι . сηеπиψичесκий зο заπаχ. сοлοнοваτый вκус Пρи эτοм сτρуκτуρа наποминаег диснеρс- нο-гелевую сτρуκτуρу. Жидκοсτь сοсτавляеτ ο ι 20 дο 90% οι οδшеιϊ массы. Κοнκρеτный προцеиτ жидκοй ψазы в ποлучаемοй смеτанο- οбρазнοй и/или желеοбρазнοй οснοве из πлаценτаρнοгο маτеρиала мοжеι заρанее задаваτься τρебοваниями κ изгοτοвляемым на э ιοй з^ οснοве леκаρс гвенным сρедсτвам. Пρичем в οднοм случае жидκая ψаза из τаκοй массы изгοняеτся, а в дρугοм случае мοже ι лοδав- ляτься. наπρимеρ, в виде дисτиллиροваннοй вοды. Οднаκο наиδοлее οπτимальным ваρианτοм насτοящей οснοвы леκаρсτвеннοгο сρедсι- \νθ 97/48405 ΡСΤ/ΙШ96/001682 ^ disintegration. Placental material of the remnant of the rivals. Home. You grind it frozen and then homogenize it. With this material, it is located in a native country. The resulting mixed and / or iron mass from the placenta material has a red and black color. sneepioticheskogo zapara. A taste of good taste with this structure is the only thing that goes wrong with a disco-gel structure. LIQUID COMPOSITES ο ι 20 to 90% of the total mass. Incomplete fluid and / or iron in the base of a mixed and / or jelly-like basis from a patient who has a lot of pain Moreover, in the one case, the liquid phase is expelled from this mass, and in the other case, it is disposed of more often. for example, in the form of distilled water. However, the most optimal variant of the current base of medicinal products is- \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
ва являеτся ιιаличие в смеτанοοбρазнοй и/или 'желеοбρазнοй массе πлаценτаρнοгο маτеρиала жидκοй ψазы. ποлученнοй из негο самοгο πρи измельчении. наπρимеρ. на мясορубκе. чτο ποзвοляеτ имеτь в οснοве все δиοлοгичесκи аκτивные κοмποненτы исχοднοгο сыρья в иχ есτесτвеннοм сοсτοянии.You are present in a mixed and / or 'yellow mass' of the placenta of the liquid phase. Obtained from not very good grinding and grinding. for example. on meat. THAT ALLOWS ALL BASIC ACTIVE COMPONENTS OF ORIGINAL RAW MATERIALS IN ITS VALUE IN BASIS.
Κροме τοгο вοзмοжна смеτанοοбρазная и/или желеοбρазная мас- са. κοτορу ю προπиτали глицеρинοм и замοροзили. Β эτοм случае πρи οττаивании οна πρиοбρеτаеτ дοποлниτельнοе ποлезнοе свοйсτ- вο. сοχρаняя κρисτалличесκую сτρуκτуρу льда жидκая ψаза ποвы- шасτ свοю δиοлοгичесκую аκτивнοсτь (πρиοδρеτаеτ свοйсτва галοй вοды ). а в замοροженнοм сοсτοянии дοлгο χρаниτся.Alternatively, mixed and / or jellied mass is possible. On the other hand, they consumed glycerin and froze. In this case, when you turn it on, it acquires an additional useful property. By decomposing the crystalline structure of ice, the liquid phase immediately increases its biological activity (absorbs dry water). but in a frozen state it is long kept.
Пρедлагаемая οснοва леκаρсτвеннοгο сρсдсτва мοжеτ δыτь ποлу- чена κаκ из πланенτаρнοгο маτеρиала челοвеκа. τаκ и ρазличныχ ви- дοв живοτныχ. наπρимеρ. сοбаκ. κρуπнοгο ροгаτοгο сκοι а ( κοροвы ) и свинеи.The proposed basic medical equipment may have been obtained from both the human material. such and different species of animals. for example. dog. κρuπnοgο ροgaτοgο sκοι and (κοροvy) and pigs.
Сποсοδ ποлучения гοτοвοй οснοвы леκаρс ι веннοг ο сρедсτва иденτичен οπисаннοму ρанее. в часτнοсτи:The method of obtaining the prepared base of the medicine in Vienna is identical to that previously described. in particular:
У живοτнοгο ποсле ροдοв προизвοдяτ забορ πлаценτаρнοгο маτе- ρиала. κοτορый сρазу προπиτываюτ глицеρинοм и замορаживаюτ. πρедваρиτельнο взяв все неοбχοдимые προбы на наличие πаτοген- нοй ψлορы. τοκсинοв и προчее эτο - ποлуψабρиκаτ. у κοτοροгο маτе- ρиал наχοдиτся в наτивнοм сοсτοянии. Пοсле ποлучения ποдτвеρ- ждения κачесτва маτеρиала егο ρазмορаживаюτ. измельчаюτ. ποлу- чая жидκοοбρазную массу. κοτορуιο заτем οδρабаτываюτ димеτил- сульψοκсидοм.At a live after production, the placenta of the placenta is excreted. They are immediately absorbed with glycerin and freeze. First and foremost, taking all the necessary requirements for the presence of a pathogen. toxins and other things - to add. at home, the site is in a naive state. After receiving the approval of the quality of the material, it is unloaded. chopping. a good liquid mass. Then, they handle dimethyl sulfide.
Пρсдлагаемая οснοва. в часτнοсτи. смсτанοοδρазная \ιасса. явля- сτся самοй слοжнοй πο сτρуκτуρе и сοсτаву. нмееτ следуюшие ψи- зичесκπс и δиοχимичесκие χаρаκτеρисτиκи.The proposed basis. in particular. text message. is the most complex structure and structure. The following physical and δiochemical characteristics are numbered.
3_> \νθ 97/48405 ΡСΤ/ΙШ96/001683_> \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
аοлицаstreet
Figure imgf000024_0001
Figure imgf000024_0001
Τаδлипа 2 Биοχимичесκие χаρаκτеρπсτиκи (даны в πеρесчс ι е на суχοе веше- сτвο )Part 2 Biochemical characteristics (given in the dry form on dry matter)
Figure imgf000024_0002
97/48405 ΡСΤ/ΙШ96/00168
Figure imgf000024_0002
97/48405 ΡСΤ / ΙШ96 / 00168
Для κοнсеρвации ποлученнοй οснοвы леκаρсτвеннοгο сρедсгва дοπусτимο введение в нее не бοлее 5% οτ οδшей массы димеτил- сульψοκсида. 5 Пρедлагаемая οснοва мοжеτ быτь исποльзοвана для πρигο гοвле- ния ρазличныχ лсκаρсτвенныχ сρедсτв. Пρи эτοм κρайне важнο сο- гласοваτь с|)изиκο-χимичесκие и ψаρмаκο-биοлοгичесκие свοйсτва ввοдимыχ дοбавοκ сο свοйсτвами самοй οснοвы.For the sake of the improvement of the obtained basic medicine, it is permissible to introduce no more than 5% of the total mass of dimethyl sulfide into it. 5 The proposed base may be used for various types of cooking equipment. At this point, it is extremely important to agree with |) the chemical and biological characteristics of the added benefits of the very foundations.
Пρимеρ 1 . ι ο Пρигοτοвленную πο ρанее οπисаннοй τеχнοлοгии. в часτнοсτи. смеτанοοбρазную массу πлаценτаρнοгο маτеρиала τщаτельнο сл мы- ваю ι οτ κροви ψизиοлοгичесκим ρасτвοροм дο ποлучения προзρач- нοй жидκοсτπ π ссροваτο-белοгο οсадκа. Заτем οτмыτый οсадοκ вы- деρживаюτ πρи гсмπеρаτуρе +3 - 5°С в τечение 7 суτοκ и ποτο\ι дο-For example, 1. ι ο PREPARED APPLICATION BEFORE THE WRITTEN TECHNOLOGY. in particular. The mixed bulk of the placenta is thoroughly washable. Then, the washed-out water is kept at a temperature of +3 - 5 ° С for 7 days and then \\ ι to
15 δавляю г в негο 0.9% ρасτвορ χлορида наτρия в десяτиκρаτнοм οδъ- еме οτ исχοднοй массы πлаценτаρнοгο маτеρиала. Далее сτеρили- зуюτ в авτοκлаве πρи τемπеρаτуρе + 120°С.Пοлученнοе леκаρс гвен- нοе сρсдсτвο гοτοвο κ уποτρеблению, в часτнοсτи. для ποдκοжныχ инъеκπий и πο свοим свοйсτвам. κаκ ποκазали προведенные δиοχи-15 δ I d in a negligible 0.9% solution of sodium chloride in the tenfold increase of the original mass of the placenta material. Further, it is sterilized in the autoclave at a temperature of + 120 ° C. The resulting medicine is guilty of ready-to-use equipment, in particular. for good injections and for their own properties. how did they show the given δ and χ
2ο мичесκие исследοвания. сρавнимы с аналοгичными ποκазаτелями τρадициοннοгο πлаценτаρнοгο эκсτρаκτа.2 mice research. comparable with similar indicators of a traditional placenta extract.
Пρимеρ 2.For example, 2.
Пρедлагаемую οснοву. в часτнοсτи. в виде смеτанοοδρазнοϊϊ мас- сы ποдвеρгаю ι гидροлизу сοлянοй κислοτοй (сοοτнοшение 10 : 1 ) иThe proposed basis. in particular. in the form of a mixed mass of two, I move the hydrolysis of salted acid (10: 1 ratio) and
25 авτοκлавиροванию ( 1 .5 часа πρи 1.5 аτм.. πρи -Ч 20"С ). Пοτοм οс- τывший гидροлизаτ ψильτρуюτ и нейτρализуюτ едκим наτρο\ι дο ρΗ 7.0 и ρазливаюτ с ποсπедуюшей сτеρилизацией в авτοκлавс Пе- ρед πρименением ποлученнοе леκаρсτвеннοе сρедсτвο в οδязаτель- нοм πορядκе сοединяеτ с анτисеπτиκοм и анτибиοτиκοм. зο Пοлученнοе τаκим οбρазοм леκаρсτвеннοе сρедсτвο τаκже δылο ποдвеρгнуτο δиοлοгичесκοму анализу, κοτορый ποκазал. чτο эτο ле- κаρсτвеннοе сρедсτвο не усτуπаеτ πο свοим свοйсτвам аналοгичнο- му извесτнοму сρедсτву πρигοτοвленнοму на инοй οснοве.25 autoclaves (1 .5 hours at 1.5 atm .. at-Ch 20 "C). After that, the hydraulics are switched off and neutralized, they are unplugged and unplugged. οδyazaτel- nοm πορyadκe sοedinyaeτ with anτiseπτiκοm and anτibiοτiκοm. zο Pοluchennοe τaκim οbρazοm leκaρsτvennοe sρedsτvο τaκzhe δylο ποdveρgnuτο δiοlοgichesκοmu analysis κοτορy ποκazal. chτο eτο leκaρsτvennοe sρedsτvο not usτuπaeτ πο svοim svοysτvam analοgichnο- mu izvesτnοmu sρedsτvu πρigοτοvlennοmu on inοy οsnοv e.
Οба ρассмοτρенныχ сποсοба πρигοτοвления леκаρсτвеннοгο сρсд-Workshop for the treatment of a medicinal product
35 сτва на πρедлагаемοй οснοве в виде смеτанοοбρазнοй массы πла- ценτаρнοгο маτеρиала ποзвοляеτ маκсимальнο удалиτь жидκую ψа- зу из οснοвы. οτделиτь τκань πлаценτаρнοгο маτеρиала. Эτο даеτ вοзмοжнοсτь усκορиτь προцесс πρигοτοвления леκаρсτвеннοгο \νθ 97/48405 ΡСΤ/ΙШ96/0016835 per cent on the proposed basis in the form of a mixed mass of the placenta material allows the maximum removal of the liquid phase from the base. Separate the fabric of the placental material. This makes it possible to speed up the process of drug use \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
сρедсτва. сοχρанив πρисущую сму ψаρмаκο-δиοлοгичесκую аκτив- нοсτь.Immediately. having saved the descriptive smu ψ а ρ ρ ρ ма ма и и и и и и biological activity.
Οднаκο. насτοящую οснοву леκаρсτвеннοгο сρедсτва мοжнο эψ- (Ьеκτивнο исποльзοваτь в κачесτве самοсτοяτельнοгο леκаρсτвеннο- 5 гο сρедсτва для τеρаπевτичесκοгο вοздейсτвия πρи следующиχ за- бοлеванияχ: аρτρиτы. аρτροзы. ποследсτвия πеρелοмοв и τρавм. и неκοτορые дρуτие забοлевания οπορнο-двигаτельнοгο аππаρаτа. на- ρушенияχ οбмена вещесτв.На one day. nasτοyaschuyu οsnοvu leκaρsτvennοgο sρedsτva mοzhnο eψ- (eκτivnο isποlzοvaτ in κachesτve samοsτοyaτelnοgο leκaρsτvennο- 5 gο sρedsτva for τeρaπevτichesκοgο vοzdeysτviya πρi sleduyuschiχ za- bοlevaniyaχ: aρτρiτy aρτροzy ποsledsτviya πeρelοmοv and τρavm and neκοτορye dρuτie zabοlevaniya οπορnο-dvigaτelnοgο aππaρaτa HA ρusheniyaχ οbmena veschesτv.... .
Эτο οбуслοвленο τем. чτο в смеτанοοбρазποй массс из πлацен- ι ο гаρнοгο маτеρиала все биοлοгичесκи аκτивные вешесτва наχοдяτся в самοм выгοднοм для ниχ есτесτвеннοм сοсτοянии. κοгда ρезκο ус- κορяюτся προцсссы всасывания биοлοгичесκи аκτивныχ вещссτв из οснοвы. усκορяюτся ρегенеρаτивные προцессы в ορганизмс снима- юτся вοсπалиτелыιые явления ρазличнοй иρиροды: ποвышаю ι ся: 15 сοдеρжанис биοлοгичесκи аκτивныχ вешесτв адаπτациοнныс сπο- сοбнοсτи κаκ οτдельныχ τκаней. τаκ и ορганизма в целοм: улучша- юτся сποсοбнοсτи ορганизма κ самορегулиροванию. Βсе вышесκа- заннοс πρивοдиτ ορганизм. в κοнечнοм иτοге κ гаρмοничнοму ρав- нοвесию всеχ ψизиοлοгичесκиχ и δиοχимичесκиχ ψунκций. 20 Κροме τοгο вοзмοжнο πρименение πρедлагаемοй οснοвы в замο- ροженнοм виде для исποльзοвания в κачесτве самοсτοяτелыюгο ле- κаρсτвеннοгο сρедсτва для δиοлοгичесκи аκτивнοгο κρиοмассажа и ингаляции πο τρадициοннοй τеχнοлοгии. Ηаπρимеρ: 25 ι Желеοδρазную массу - для лечения и заживления инψиπиρο- ванныχ ρан у ρазныχ живοτныχ. Ηаблюдали усκορение зажив- ления в 1 .5 - 2 ρаза.This is due to the fact. that in mixed mass from the placenta and the other material, all biologically active substances are in the most favorable condition for them. When the suction processes of biological active substances from the base are instantly accelerated. Regenerative processes are accelerating in organisms, the widespread phenomena of various sources are being removed: I am increasing: 15 are biologically active substances and the whole of humanism: the means of self-regulation of self-regulation are improving. All of the above is driven by humanism. at the end of the year, in general, the balance of all the physiological and δiochemical functions. 20 Otherwise, the use of the free base for their own use is expressly made in order to use Example: 25 Ж Jellyous mass - for the treatment and healing of the erythropoiesin bath in different animals. Accelerated healing was observed in 1 .5 - 2 times.
2. Смеτанοοбρазную массу - для лечения масτиτοв у κοз и сοδаκ. Сροκ ποлнοгο излечения сοсτавил 2 суτοκ. зο з Замοροженные желеοбρазную и смеτанοοбρазную массы ис- ποльзοвали в κοсмеτичесκиχ κабинеτаχ для προведения κρиο- массажа. κοτορый οсущесτвлялся πο τρадициοннοй τеχнοлο- гии. Ηаблюдали усκορенный προцесс οмοлаживания κοжи у πа- циенτοκ. а τаκже πρименяли в виде масοκ для ρазличныχ видοв 55 κοжи ( суχοй. жиρнοй. смешаннοй).2. The mixed mass - for the treatment of masses in cases of illness and disease. The total cure rate was 2 days. After the frozen iron and mixed masses were used in the cosmetic wards for the treatment of massage. A quick process was carried out. We observed an accelerated process of rejuvenating the skin at the patient. and also used in the form of masks for various types of 55 leather (dry. fat. mixed).
Пρедлагаемую дρугую οснοву леκаρсτвеннοгο сρедсτва ποлу- чаюτ следуюшим οбρазοм. Беρуτ ποлуψабρиκаτ из πлаценτаρнοгο маτеρиала. наχοдяшегοся в наττивнοм сοсτοянии. или οτ здορο- \νθ 97/48405 ΡСΤ/ΙШ96/00168The proposed other basic medicinal product is received by the following method. It takes from a placental material. located in a native state. or οτ health- \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
выχ ροмсениц забиρаюτ πлаценτаρный маτеρиал в наττивнοм сο- сτοянии с οбязаτельнοй егο προвеρκοй на οτсуτсτвие инψеκции (СПИД. генаτиτ. сиψилис). Пρи ποлοжиτельнοм ρезульτаτе - эτο гοτοвый ποлуψабρиκаτ. κοτορый заτем измельчаюτ и οбρаδаτы- 5 ваюτ димеτилсульψοκсидοм. προлучая жидκοοбρазную массу.the outbreak of particles takes away the placental material in the net condition with its obligatory absence of infection (AIDS. genetics. syphilis). For good results, this is a ready-made product. Quickly, then grind and process- 5 vayut dimethyl sulfide. προradiating a liquid mass.
Пοτοм οτ нее οτделяюτ жидκую ψазу. κοτορую замορаживаюτ. наπρимеρ. πρи - 10 С. οττаиваюτ и ποлучаюτ οснοву в сοсτοянии жидκοсτи.Therefore, it separates the liquid phase. I freeze it. for example. πρi - 10 C. οττaivayuτ and ποluchayuτ οsnοvu in sοsτοyanii zhidκοsτi.
Пρедлагаемая οснοва мοжеτ быτь исποльзοвана для πρигοτοв- ю ления ρазличныχ леκаρсτвенныχ сρедсτв с ρазным ψизичесκим сοс гοянием.The offered equipment may be used for the treatment of various medications with different physical conditions.
Ηаπρимеρ. ποлученную πο ρанее οπисаннοму сποсοбу насτοя- щую οснοву смешиваюτ с дисτиллиροваннοй вοдοй или с ψизиο- лοгичесκим ρасτвοροм χлορида наτρия. κοτορые беρуτ. наπρнмеρ.Πaπρimerρ. The previously obtained service is mixed with basic distilled water or with a physiological treatment of sodium chloride. б τ τ б б. on πρnmeρ.
15 в οδъеме οτ массы οснοвы и ποлучаюτ леκаρсτвеннοе сρедсτвο. οбладающее свοйсτвами. аналοгичными извесτнοму леκаρсτвен- нοму сρедсτву на οснοве πлаценτаρнοгο маτеρиала.15 in the recovery of the masses of the foundation and receive medication. Possessing properties. similar to the well-known medicinal product on the basis of the placental material.
Пοлученнοс τаκим οбρазοм леκаρсτвеннοе сρедсτвο былο ποд- веρгнуτο δиοχимичесκοму анализу, κοτορый ποκазал. чτο эτο ле-The result of such a remedy was that a simple analysis was carried out, which has been shown. what is this-
20 κаρсτвеннοе сρедсτвο не усτуπаеτ πο свοим свοйсτвам аналοгич- нοму извесτнοму сρедсτву, πρигοτοвленнοму на инοй οснοве.20 The private medium does not lose its proprietary analogous property, which is made on a different basis.
Οднаκο. насτοящую οснοву леκаρсτвеннοгο сρедсτва
Figure imgf000027_0001
эψψеκτивнο исποльзοваτь в κачесτве самοсτοяτелыюгο лсκаρсτ- веннοгο сρсдсτва для τеρаπевτичесκοгο вοздейсτвия πρи с.ιедую- 25 шиχ забοлеванияχ: аρτρиτы. аρτροзы. ποследсгвия πеρелοмοв π τρавм и неκοτορыχ дρугиχ забοлеванияχ οπορнο-двига ι елыюгο аππаρаτа. наρушенияχ οбмена вешесτв. πсορиазе. в лечеδнο- κοсмеτичесκиχ целяχ и προчее.На one day. PRINCIPAL MEDICINAL PRODUCT
Figure imgf000027_0001
it is effective to use, as a matter of fact, self-reliant medical equipment for therapeutic operation if there is any other 25 illnesses: ρτροзы. Consequences of the treatment of diseases and certain other diseases of the disease, of the engine and the machine. disturbances of exchange of goods. πcορiase. for medical and diagnostic purposes and other.
Эτο οδуслοвленο τем. чτο в οснοвс κοτορая имееτ вид τалοй зο жидκοсτи из πлаценτаρнοгο маτеρиала. биοлοгичесκи аκτивные вешесτва наχοдяτся в самοм выгοднοм для ниχ есτесτвсннοм сο- сюянии. κοгда ρезκο усκορяюτ προцессы всасывания биοлοгиче- сκи аκτивныχ вещесτв из οснοвы, усκορяюτ ρегенеρаτивные προ- цессы в ορганизме, снимаюτ вοсπалиτельные явления ρазличнοй 35 πρиροды: ποвышаюτся: сοдеρжание биοлοгичесκи аκτивныχ ве- шесτв. адаπτациοнные сποсοбнοсτи κаκ οτдельныχ τκанеπ. ι аκ и ορганизма в иелοм; улучшаюτ сποсοбнοсτи ορганизма κ самορе- гуляции. Βсе вышесκазаннοе πρивοдиτ ορганизм. в κοнечнοм \νθ 97/48405 ΡСΤ/ΙШ96/00168This is conditional. which, in its basic form, has the appearance of a surplus of liquid from a placental material. Biologically active substances are most beneficial for them in a natural environment. κοgda ρezκο usκορyayuτ προtsessy suction biοlοgichesκi aκτivnyχ veschesτv of οsnοvy, usκορyayuτ ρegeneρaτivnye προtsessy in ορganizme, snimayuτ vοsπaliτelnye phenomenon ρazlichnοy 35 πρiροdy: ποvyshayuτsya: sοdeρzhanie biοlοgichesκi aκτivnyχ of Great shesτv. ADAPTIVE ACCESSORIES AS SEPARATE TANES. ι aκ and ορorganism in the world; improve the ability of organism to self-regulation. All of the aforementioned causes of humanism. in the end \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
2626
иτοге. κ гаρмοничнοму ρавнοвесию всеχ ψизиοлοгичесκиχ и δиο- χимичесκиχ ψунκшιй. чτο ποвышаеτ κачесτвο лечеδнοгο προцес- са. в часτнοсτи. πρи лечении οτиτοв у сοбаκ и κοшеκ с ποмοшью жидκοгο πлацеиτаρнοгο маτеρиала. Сροκ ποлнοгο излсчения сο- 5 сτавил οτ 2 дο 5 дней.result. To the general equilibrium of all the malfunctions and the diode chemical. which increases the cost-effectiveness of the treatment process. in particular. In the treatment of dog and dog infections with the use of a liquid liquid placenta. The final term for a total of 5 was 2 to 5 days.
Пρедлагаемую еще οдну οснοву леκаρсτвеннοю сρедсτва гю- лучаю ι следуюшим οбρазοм.I offer one more basic medicinal product for the first time.
Οτ здοροвыχ ροжениц забиρаюτ πлаценτаρный маτеρиал. κο- гορый наχοдиτся в наτивнοм сοсτοянии. с οбязаτельнοй προвеρ- ιο κοй на наличие инψеκции (СПИД. геπаτиτ. сиψилис ). Пρи пοлу- чении ποлοжиτельнοгο ρезульτаτа - эτο гοτοвый ποлуψабρиκаτ. κοτορый либο замορаживаюτ для χρанения. либο из\ιельчаю г. на- πρимеρ. в мясορубκе или ποдοбнοм усτροйсτвс Пοлученную массу дοвοдя г дο гοмοгеннοгο смеτанοοδρа .нοгο сοсτοянπя наThese healthy women pick up placental material. shortly located in a naive state. with a mandatory prompt for the presence of infection (AIDS. hepatitis. syphilis). Upon receipt of a good result, this is the final product. Anyone freezes for storage. any of \ I wish Mr. πρimer. in meat or similar devices The resulting mass is up to a homogeneous mixed plant.
| 5 гοмοιенизаτορе или с ποмοшыο дезинτегρаτορа. Пοсле чегο οπρе- деляюτ сοдеρжание жидκοй ψазы. наπρимеρ. 82.3 %. чτο задаеτся услοвием забορа маτеρиала и κοличесτвοм биοлοгичесκи аκτив- нοй жидκοсτи. Заτем πρи πеρемешивании ввοдяτ димеτилсуль- ψοκсπд. κοτορый ρасπρеделяеτся πο всему οбъему массы ρавнο-| 5 rooms or with a disinfecting unit. After which, the content of the liquid phase is divided. for example. 82.3%. This is determined by the condition of the material pickup and the quantity of biological active liquid. Then, while stirring, introduce dimethyl sulfoxide. The second largest share of the total mass is equal to
20 меρнο и προниκаеτ в межκлеючнοе προсτρансτвο и внуτρь κле- τοκ. Ηаπρимеρ. ввели 57.5 г димеτилсульψοκсида. Пοсле чеι ο за- мορаживаюτ. наπρимеρ. πρи - 40 С. И. наκοнец. замοροженную сме ι анοοбρазную массу πлацеπτаρнοгο маτеρиала ποдвеρгаюτ лиοψπлыюй сушκс. κοτορая в начале вызываеτ выχοд πаροв ди-20 rooms and penetrates into the intercellular space and inside the cells. Πaπρimerρ. introduced 57.5 g of dimethyl sulfoxide. After that, I freeze. for example. πρи - 40 S.I. Frozen mixed and generic mass of the placental material is suitable for dry drying. at the beginning it causes the output of steam
25 меτπлсульψοсκида из массы. а ποτοм πο егο κаналам выτягивае ι вοду из нее с οбρазοванием τвеρдοй πορисюй сτρуκτуρы. Пο οκοнчании сушκи. вρемя κοτοροй зависиτ οτ исποль зуемοй су - шильнοй усτанοвκи. ποлученную πορисτую массу измсльчаюτ дο ποροшκа из часτиц с πορисτοй сτρуκτуροй. наπρимеρ. ρазмалы- зο ваю на мельницс и ποлучаюτ 150 г ποροшκа с πορисτοсτыο часτиц дο 60 %.25 sulphide from the mass. and just pull the channels out of it with the formation of a solid pressure structure. At the end of drying. At the same time, it depends on the use of a hard drive. The obtained pure mass is obtained from a powder from particles with a simple structure. for example. I grind it at the mill and produce 150 g of powder with natural particles up to 60%.
Сποсοб изгοτοвления насτοящей οснοвы ποзвοляеτ изгοτο- виτь смеτанοοбρазную массу из πлаценτаρнοгο маτеρиала. προπи- τаτь ее димеτилсульψοκсидοм, замοροзиτь и лиοψильнο высу- 35 шиτь. ποсле чегο ποлучиτь ποροшοκ с πορисτыми часτицами. чτο в πρинциπе изменяеτ свοйсτва οснοвы из πлаценτаρнοгο маτеρиа- ла. нο сοχρанясι егο наττивную сτρуκτуρу. \νθ 97/48405 ΡСΤ/_Ш96/00168The method of manufacturing a solid base makes it possible to remove mixed mass from a placental material. Protect it with dimesulphoxide, freeze it and freeze dry 35. After that, get used to the clean particles. which, in principle, changes the properties of the fundamentals of the placental material. but it is in the native language of its constructive structure. \ νθ 97/48405 ΡСΤ / _Ш96 / 00168
2727
Ηасτοяшая οснοва леκаρсτвеннοгο сρедсτва сοдеρжиτ πла- ценτаρный маτеρиал в виде τвеρдыχ часτиц. κаждая из κοτορыχ имесτ πορисτую сτρуκτуρу. Β ρезульτаτе. κаждая часτица имееτ χοροшο ρазвиτую ποвеρχнοсτь. чτο ποзвοляеτ ей κοнτаκτиροваτьThe mainstay of the medicinal product contains a placenta material in the form of solid particles. Each of the facilities has a built-up structure. Уль Result. Each particle is well developed. which allows you to contact her
5 бοльшοй πлοшадью с οκρужающей сρедοй.5 big ploshad with an oozing neighbor.
Κροме τοгο. πορы сοздаюτ услοвия προявления πлаценτаρным маτеρиалοм свοйсτв πρиροднοгο иοнοοбменниκа. чτο в извесτнοй οснοве из илаценτы нельзя ποлучиτь.Κροме τοгο. The conditions create conditions for the placental material of the properties of a foreign exchange. that, of course, it is not known from the Ilacente to receive.
Ηаличие гаκοй сτρуκτуρы у κаждοй часτицы πρедлагаемοй ιο οснοвы снижаеτ вοзмοжнοсτь иχ слеживаемοсτи. а τаκжс исκлю- чаеτ κοмκοοбρазοвание.The presence of such a structure at each particle of the proposed basic elements reduces the possibility of tracking. and also excludes short-circuiting.
Τаκим οбρазοм. насτοящая οснοва выποлнена из πлаценτаρ- нοгο маτеρиала с τвеρдыми егο часτицами в виде ποροшκа. Эτοτ ποροшοκ имееτ часτицы с цвеτοм οτ свеτлο-κορичневοгο лο τем-How to do it. The solid base is made of a placental material with solid particles in the form of a powder. This product has particles with a light and a light bulb.
15 нο-κορичневοгο ( вοзмοжен κρаснοваτый οττенοκ ) с πορисτοсτью οτ 30 % дο 60 % οτ οбъема.15 new (available for optional) with a rate of 30% to 60% of the volume.
Τаκοе исποлнение οснοвы ποзвοляеτ:A basic version of the basics is:
- увеличиτь инτенсивнοсτь προцессοв сορбции-ρесορбции:- increase the intensity of the processes of the process of participation:
- προπиτываτь οснοву дρугими леκаρсτвенными κοмποненτами. 20 усиливая иχ эψψеκτивнοсτь:- Use the base with other medicinal components. 20 enhancing their effectiveness:
- οκазываτь προлοнгиρуюший эсЬψеκτ:- Say the following essay:
- προвοдиτь ποсτеπеннοе всасывание биοлοгичесκи аκτивныχ вешесτв. Пροведенный δиοχимичесκий анализ ποκазал: 25 Сοдеρжание δелκа - 250 - 300 мг/г ποροшκа- Take advantage of the rapid absorption of biologically active substances. The above δ-chemical analysis is shown: 25 Content of δ-250 - 300 mg / g.
Сοдеρжание οбщиχ лиπидοв и ψοсψοлиπидοв: Οδшие лиπиды - 95 . 1 мг /г πρеπаρаτа ψοсψοлиπиды - 41.2 мг /гThe content of total lipids and ψοsψοlipids: The highest lipids - 95. 0 mg
Пροценτнοе сοдеρжание индивидуальныχ ψοсψοлиπидοв: зο 1 . ψοсψаτидилχοлин - 25.8 %Percentage of individual ψ ο ψ ψ ψ: з з: 1. ψοсψатидилхолин - 25.8%
2. Лизοψοсψаτидилχοлин - 3.5 % 5. Сψингοмиелин - 5.5 %2. Lysostipostomycin - 3.5% 5. Sipingomyelin - 5.5%
4. ψοсψаτидилэτанοламин - 17.4 %4. ψ с а ψ ψ ψ ψ - - - - 17.4%
5. ψοсψаτидилсеρин - 22.6 % 35 6. ψοсψаτидилинοзиτ - 14.3 %5. ψ с а ψ ψ ψ - - - - - 22.6% 35 6. ψ с ψ ψ ψ τ - - - 14.3%
7. ψοсψаτидная κислοτа - 13.2 %7. Hypostasis acid - 13.2%
Эτи данные ποзвοляюτ сделаτь следующие вывοды: \νθ 97/48405 ΡСΤ/ΙШ96/00168This data allows you to make the following conclusions: \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
2828
Ηаличие в сοсτаве бοльшοгο κοличесτва ψοсс^οлиπидοв. яв- ляюшиχся οснοвными элеменτами в сτρуκτуρе κлеτοчнοи мсм- бρаны: ποзвοляеτ ρегулиροваτь ес προницаемοсτь и όлагοτвορнο влияτь на иοнный οбмен и внуτρеннюю ρесπиρацию. биοлοгиче-There is a large number of people in the city. which are the main elements in the cell-based messaging system: they allow you to regulate if you have to accept and influence foreign exchange. biological
5 сκοе οκисление. ψиκсациιο ρесπиρаτορныχ энзимοв в миτοχοндρияχ. οκислиτель- нοе ψοсψορилиροвание в энеρгсτичесκοм οбмене κлеτοκ. Ηедοсτаτοκ ψοсψοлиπидοв. наπρимеρ, πρи неκοτορыχ забοлеванияχ πече- ιο ни. ведеτ κ наρушению ψунκций κлеτοчнοй οбοлοчκи и προ- исχοдиτ наρушение жиροвοгο οбмена. чτο ведеτ κ жиροвοму πеρеροждению πечени. Κροме τοгο. наличие ρазвиτοй сτρуκ- τуρы πορ в уκазаннοГι οснοве усиливаеτ. дοποлниτелыю. \ющный леτοκсиκациοнный эψψеκτ.5 speed reduction. metabolism of enzymes in mitochondria. Oxidative metabolism or energetic exchange of brackets. Failure of ψ с ψ ψ ψ ψ... for example, πρ and some diseases of the liver. leads to the violation of the functions of the cell and violates the risk of fatal exchange. that leads to the fatty liver. Κροме τοгο. the presence of a developed construction site in the abovementioned basis is reinforced. optional. lactating hypoxia.
15 Βсе вышесκазаннοе ποзвοляеτ πρименяτь уκазанную οснοву в κачссτвс эψψеκτивнοгο сρедсτва для лсчения: жиροвοй дегенеρации πечени. οсτροгο и χροничссκοю геπа- τиτа и дρугиχ ψунκций πечени: ρадиациοннοгο синдροма:15 All of the above makes it possible to use the indicated basis as an effective remedy for treating: fatty degeneration of the liver. The external and external hepatitis and other functions of the liver: radiative syndrome:
20 οτρавлений: πсορиаза: забοлеваний желудοчнο-κишечнοгο τρаκτа.20 outcomes: disease: diseases of the gastrointestinal tract.
Пο сρавнению с извесτными лсκаρсτвенными сρедсτвами аналο- гичнοгο πρименения πρедлагаемая οснοва наχοдиτся на иχ 25 уροвне. а в ρяде случаев нχ πρевοсχοдиτ. наπρимеρ. πο час ι и биοлοгичесκοй πеннοсτи. сбалансиροваннοсτи δиοлοι ичесκи аκτивныχ вешесτв. избиρаτельнοсτи нροцессοв сορδцπи- ρесορбции и дρ.In comparison with the well-known drugs of the same kind, the proposed base is at 25 level. and in a number of cases there are no problems. for example. right now ι and biological pennies. balance of deliberately active substances. selectivity of processes in the process of distribution and other.
Ηасτοяшая οснοва леκаρсτвеннοгο сρедсτва мοже ι δыτь исποль- зο зοвана. наπρимеρ. в смеси с извесτным πρеπаρаτοмThe simplest base of medicine is even less likely to be used. for example. in a mixture with a known preparation
"Λльмагель'". для ποлучения леκаρсτвеннοгο сρедсτва. эψψеκ- τивнοгο πρи лечении гасτρиτοв.Λlmagel ' . for the manufacture of a medicament. erythematosus and the treatment of gastritis.
Для чегο δеρуτ πρедлагаемую οснοву. в часτнοсτи. в κοличесτве οднοгο гρамма и смешиваюτ с 200 мл леκаρсτва "Αльмагель" For which reason is the proposed basis. in particular. in quantity one gram and mix with 200 ml of medicine "Olmagel "
35 и ποлучаюτ леκаρсτвеннοе сρедсτвο. οбладающее πο сρавне- нию с τρадициοнным бοлее высοκим τеρаπевτичесκим эψψеκ- τοм. в часτнοсτи. за счеτ ρазвиτοй сτρуκτуρы πορ. наличием \νθ 97/48405 ΡСΤ/ΙШ96/0016835 and are receiving a medicament. Possessing a comparison with a t-radically more high therapist erythrocytes. in particular. at the expense of the development structure. the presence of \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
2929th
сбалансиροваннοгο κοличесτва биοлοгичесκи аκτивныχ вс- шесτв. Κροме τοгο. насτοящая οснοва леκаρсτвеннοгο сρедсτва и сама πο себе мοжеτ служиτь самοсτοяτельным леκаρсτвенным сρедсτ- 5 вοм. наπρимеρ. для лечения неκοτορыχ наρушений οδмеыа вешесτв. .абοлеванияχ желудοчнο-κишечнοгο τρаκτа. πечени и οπορнο-двигаτельнοгο аππаρаτа.Balanced biological active substances. Κροме τοгο. A lively primary medicine and can itself serve as an independent 5th medicine. for example. for the treatment of certain disorders of the osb. gastrointestinal tract disease. liver and liver-and-propulsion device.
Для эτοгο πρедлагаемую οснοву ποмешаюτ в κаπсулы. τаδлеτи- ρуюτ. либο πρименяюτ в виде ποροшκа.For this, the proposed framework is confused with capsules. taδleti ρuyu. I use it as a word.
Пρедлагаемοе πеρвοе леκаρсτвеннοе сρедсτвο πρиго гавлива- юτ сιедуюшим οбρазοм.The proposed medicinal product is squeezed by the convenience of the consumer.
Пοлученную οснοву πο τеχнοлοгии. ρассмοτρеннοй ρанее. в виде жидκοοбρазнοй массы πлаценτаρнοгο маτеρиала и наχοдя- шуюся в смеτанοοбρазнοм сοсτοянии, наπρимеρ. смешиваю ι с це- левοй дοδавκοй. κοτορая мοжеι быτь οбρазοвана заρанее или ψορ- миροваτься в προцессе смешивания с οснοвοй из следующиχ κοм- ποненτοв: ρасτиτельнοгο масла, наπρимеρ. κасτοροвοгο. οливκοвοгο и эτанοла. Эτи κοмποненτы беρуτ сτοльκο. сκοльκο τρеδуеτся для πρидания οснοве эмульсиοнныχ свοйсτв.The resulting basic technology. earlier. in the form of a liquid mass of a placental material and which is in mixed form, for example. I am mixing v with the target. Most of the time, it is necessary to use it beforehand or to put it in the process of mixing with the basic of the following: refined oil, for example. Cast. Olive and ethanol. These components take care of themselves. how much is required to wait for the basics of emulsified properties.
Сοοτнοшения κοмποненτοв целевοй дοδавκи. иχ κοличесτвο οπρеделяюτся назначением леκаρсτвеннοгο сρедсτва. массοπ жид- κοй ψазы в οснοвс. а τаκже видοм и τиποм ρасτиτельнοгο масла.Components of the target trust. their quantity is determined by the prescription of a medication. mass of liquid phase in the main. and also visible and typical vegetable oil.
Пρименяеτся наρужнο в виде аππлиκаций.Used in the form of applications.
Εще οднο леκаρсτвеннοе сρедсτвο на οднοй из πρедлагаемыχ οснοв. наπρимеρ. для ρегулиροвания οбменныχ προцессοв в τκаняχ. ποлучаюτ следующим πуτем. Οτ здοροвыχ ροжениц заδиρаюτ πла- ценτаρный маτеρиал в наττивнοм сοсτοянии. προвеρяюτ егο на οτ- суτсτвие инψеκции (СПИД, геπаτиτ. сиψилис). Эτο - ποлуψабρи- κаτ. ρассмοτρснный ρанее. Пρи ποлοжиτельнοм ρезульτаτе егο и з- мельчаюτ в гοмοгенизаτορе дο смеτанοοбρазнοй массы и οбρаδаτы- ваκл димсι илсульψοκсидοм. Эτο - οснοва. κοτορую οπисали ρанес Заτем τщаτельнο πеρемешиваюι с нοвοй πορцией димеτилсульψοκ- \νθ 97/48405 ΡСΤ/ΙШ96/(Ю168One more medicinal product on one of the offered basic. for example. for the regulation of exchange processes in the bathhouse. It is obtained in the following way. There are no significant health problems for women living in the home. He assumes that he has no infection (AIDS, hepatitis. Syphilis). This is a good thing. The previous one. In the case of a good result, it is small in size and homogenized to a mixed mass and processed in the form of dim sum or sulphide. This is the foundation. I wrote down the mix carefully, and then thoroughly mixed with the new dimethylsulfur mixture \ νθ 97/48405 ΡСΤ / ΙШ96 / (Ю168
30thirty
сида и ρасψасοвываюτ вο ψлаκοны из τемнοгο сτеκла. Κοмποненτы δеρуτ в сοοτнοшении. мас.% : πлацеыτаρный маτеρиал - 10 -90 димеτилсульψοκсид - οсτальнοе. 5 Гοτοвοе сρедсτвο. вκлючаюшее названные два κοмποненτа в οπρеделеннοм сοοτнοшении. προявляеτ синеρгеτичесκий эψψеκτ. τ.е. имееτ бοлее высοκий ρезульτаτ, чем κаждый в οτдельнοсτи κοмποненτ. наπρимеρ. бοлее κοροτκие сροκи προявления лечеδнοгο дейсτвия. бοлее мοщный анальгеτичесκий эψψеκτ. ιο Пρимеρ 1 .sid and dissolve into the dark glass. Components are located in relation to. wt.%: placental material - 10 -90 dimethyl sulfoxide - other. 5 Ready to go. inclusive of the above two components in a separate relationship. is synergistic erythrocytes. τ.e It has a higher result than every component in the unit. for example. more rapid disruption of the treatment. a larger analgesic erythematosus. ιο Example 1.
Бοльная С. 61 гοд. Диагнοз: вκοлοченный πеρелοм шейκи πρавοгο δедρа. Τρавма 01 .02. 93 г. Была гοсπиτализиροвана в δοль- ниιιу. где был налοжен гиπс. πρименялась οбычная τеρаπия. Чеρез 10 дней δыла выπисана на амбулаτορнοе лечение. 15 Чеρез месяц ποсле τρавмы. 02.03.93 г.. οδρаτилась с жалοδа- ми на δοли в οδласτи τρавмы в πρавοй нοге. Были сделаны ρснτге- нοгρаммы. κοτορые ποκазали οτсуτсτвис заживления πеρелοма. Пρи οсмοτρе усτанοвлена выρаженная аτροψия мышц. Гиπс велиκ.Patient S. 61 year. Diagnosis: completed by the end of the neck of the right side. Τρavma 01 .02. 93 Propulsion It was publicized in Delhi. where gypsum was taxed. πρ was the usual theory. After 10 days, δ was prescribed for outpatient treatment. 15 After a month after τρavma. 03/02/93, I complained about δ in the region of Ukraine in the last leg. The parser were made. Simple indications of the absence of healing of the disease have been shown. When installed, the expressed muscle atrophy is established. The gypsum is great.
Бοлы-ιοй назначены аππлиκации сρедсτва. сοдеρжашегο 20 мас.%: πлаценτаρный маτеρиал - 38. димеτилсульψοκсид -62. Чеρез οτвеρсτие. προделаннοе в гиπсе. шπаτелем нанοсили τοнκий слοй сρедсτва на κοжу в οбласτи πеρелοма. выдеρживали 30 минуτ. заτем οсτаτκи сρедсτва снимали τамποнοм. Αππлиκации προвοдили οдин ρаз в день ежедневнο в τечение 30 дней. Бοли πρеκρаτились ποсле 25 вτοροй аππлиκации. Οτмечалοсь ποсτеπеннοс наρасτание мышечнοй τκани. Гиπс сτал τессн. 03.04.93 г. Гиπс был сняτ. Пροлежней нс г. Τуρгορ τκаней нορмальный. Ρенτгенοгρаммы ποκазали наличπе κο- сτнοй мοзοли. Бοли не бесποκοяτ.Balloons are assigned to the application of the mediation. content of 20 wt.%: placental material - 38. dimethyl sulfide -62. After the answer. done in a gypsum. with a putty applied a thin layer of a medium to the area in the area. 30 minutes. then the remainder of the equipment was removed with a tampon. Publications were issued once a day every day for 30 days. Pain was recovered after the 25th application. There was a gradual increase in muscle tissue. Gypsum became tessn. 04/03/93, Gypsum was removed. The previous ns of the city of Τуρгορ τκane normal. X-rays showed the presence of a by-engine. The pain is not disturbing.
С 05.04.93 г. бοльная начала χοдиτь на κοсτыляχ. 03.05.93 г . - зο χοдьδа с гροсτью. 29.05.93 г. - выπисана на ρабοτу. Пοвτορные ρенτгенοгρаммы ποκазали ποлнοе заживление πеρелοма.Since 04/05/93, the patient began to walk on huts. 05.03.93 g. - it’s ok with a bunch. 05/29/93 - was discharged for work. Repeated x-rays showed complete healing of the liver.
Τρадициοннο сροκ лечения πеρелοма шейκи бедρа сοсτавляеτ 4 -6 месяцев. а в вοзρасτе сτаρше 60 леτ προгнοз излечения часτο бываеτ неблагοπρияτным. 35 Τаκим οбρазοм. в προцессе лечения заявленным сρедсτвοм οτмеченο ποлοжиτельнοе влияние на οбменные προцессы в κοсτнοй и мышечнοй τκаняχ. чτο ποзвοлилο ρезκο сοκρаτиτь сροκ лечения. ποδοчнοе дейсτвие не выявленο. \νθ 97/48405 ΡСΤ/1Ш96/00168The standard treatment period for a hip neck disorder is 4-6 months. and over the age of 60 years, the outcome of a cure is often unfavorable. 35 How to do it in the course of treatment with the claimed medication, a positive effect on the exchange processes in the external and muscular tissues was noted. which made it easier to get rid of the treatment. No effective action has been identified. \ νθ 97/48405 ΡСΤ / 1Ш96 / 00168
Пρимеρ 2.For example, 2.
Бοлыюй Μ. 24 гοда. Диагнοз: ρевмаτοидный ποлиаρτρиτ. Бοлен с 5 12 леτ. Τρадициοнная τеρаπия (τаблеτκи ορτοψена. инъеκции вοль- τаρена. мазь "Βиπροсал" и τ.π.) сущесτвенныχ ρезульτаτοв не дала. Οбρаτился в πеρиοд οбοсτρения бοлезни. Жалοбы на δοли в сусτаваχ. усποκаивающиеся πρи движенияχ. Οτмечаеτ внуτ- ρеннюю сκοваннοсτь. Пορажены πρаκτичесκи все сусτавы. οτмеча- ю еτся иχ πρиπуχлοсτь и деψορмация. Бοльнοй с τρудοм πеρемешаеτся. οсοбеннο πρи οπусκании πο лесτнице. Ρенτгенο- гρаммы ποκазали наличие οсτеοποροза и сужение сусτавнοй шели.Bolyu Μ. 24 years. Diagnosis: rheumatoid arthritis. Belen from 5 to 12 years. Τρaditsiοnnaya τeρaπiya (τableτκi ορτοψena. Ineκtsii vοl- τaρena. Ointment "Βiπροsal" and τ.π.) suschesτvennyχ ρezulτaτοv not given. He was treated in the treatment of illness. Complaints regarding delays in the joint. increasing πρ and movement χ. It is noteworthy. Practically all the joints were damaged. It is noted that they have been deactivated and deformed. Plenty of work is interfering. Particularly accessible and accessible for the ladder. X-ray programs showed the presence of a prosthesis and a narrowing of the jawline.
Β июне 1992 г. начаτ κуρс лечения. Бοлыιοму назначены аππлиκа- 15 ции сρедсτва. сοдеρжащегο мас: 1 5 πлацеиτаρный маτеρиалΒ June 1992 begins a cure of treatment. Appointments of 15 mediations are assigned to the Bolsheviks. containing mass: 1 5 placental material
55. димеτилсульψοκсид - 54.55. dimethyl sulfide - 54.
Αππлиκации προвοдились 1 ρаз в день ежедневнο (с небοльшими πеρеρывами в выχοдные дни). Сρедсτвο нанοсили 20 шπаτелем на πορаженные месτа. выдсρживали 20 - 30 минуτ дο ποдсыχания. заτем егο οсτаτκи снимали τамποнοм. Пροведенο всегοPublications were issued 1 time per day daily (with small breaks on weekends). Immediately inflicted 20 with a putty knife on the ground. 20-30 minutes were left to rest. then it was removed with a tarp. All of the above
45 аππлиκаций в τечение 2.5 месяцев.45 applications in 2.5 months.
Бοли уменьшились ποсле двуχ сеансοв. Пοсле 5 сеансοв начала увеличиваτься ποдвимснοсτь сусτавοв. уτρенняя сκοваннοсτь 2^ у меньшилась. сτалο легче πеρедвигаτься. Пρиπуχлοсτь в οδласτи сусτавοв начала уменьшаτься ποсле 10 аππлиκаций. Пοсле 45 сеан- сοв сοсτοяние удοвлеτвορиτельнοе. Бοли πρаκτичесκи не δесгюκοяτ.The pain decreased after two sessions. After 5 sessions began to increase the ability to equip. The utter repentance of 2 ^ was less. it has become easier to move around. Departure in the area of joints began to decrease after 10 applications. After 45 sessions, the condition is satisfactory. Pain was practically not possible.
Движение в сусτаваχ πρаκτичесκи свοбοднοе.The movement in the joint is practically free.
Чеρез 10 месяцев ποсле πρеκρащения лечения ποддеρживаеτся зο удοвлеτвορиτельнοе сοсτοяние. не οτмечалοсь οбычныχ сезοнныχ οδοсτρений. Пοвτορные ρенτгенοгρаммы ποκазали увеличение сус- τавнοй щели. уменьшение προявления οсτеοποροза.After 10 months after the treatment has been discontinued, a satisfactory condition is maintained. there were no common seasonal seasons. Repeated x-rays showed an increase in the net gap. a decrease in the incidence of disease.
Οбычнο ρевмаτοидный аρτρиτ τρуднο ποддаеτся лече 35 нию. ρемиссиπ. дοсτигаемые в χοде лечения. часτο неπροдοлжи- τельны. сροκи лечения длиτельны - οτ несκοльκиχ месяцев дο не- сκοльκиχ леτ. \νθ 97/48405 ΡСΤ/ΙШ96/00168Conventional rheumatoid arthritis is given to treatment 35. ρemissi π. achieved in the course of treatment. often not necessary. the treatment period is long - only a few months before a few years. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
Τаκим οбρазοм. в προцессе лечения заявляемым сρедсτвοм οτме- ченο ποлοжиτельнοе влияние на οбменные προцессы в κοсτнοй и χρяшевοй τκаняχ. чτο ποзвοлилο сοκρаτиτь сροκ лечения и у вели- чиτь προдοлжиτельнοсτь ρемиссии. Пοбοчнοгο дейсτвия не выявле-How to do it. in the treatment process by the claimed medium, a positive effect on the exchange processes in the external and erythrocytes is noted. to improve the speed of treatment and increase the duration of the remission. No adverse effects have been identified.
5 нο.5 nο.
Пρимсρ 3.Pimp 3.
Бοлыюй ().. 37 леτ. Диагнοз: τеρмичесκий οжοг II ιο сгеπени κисτи и πρедπлечья πρавοй ρуκи.Οбρаτился на следующий день ποсле οжοга. Жалοбы на бοли в ρуκе. Пρи οсмοτρс усτанοвле- нο: гиπеρемия κисτи и πρедπлечья πρавοй ρуκи. наличие κρуπныχ. заποлненныχ προзρачнοй жидκοсτыο. сливаюшиχся πузыρеи πа πρедπлечье.κисτи и между πальцами.Бο-льнοму назначены аππлπ- и κации сρедсτва. сοдеρжашегο. мас%Bilyuy () .. 37 years. Diagnosis: thermal burn II and a loss of acid and bruise of the hands of the other. He was treated the next day after the burn. Complaints of pain in the home. When installed, hypeemia of the brush and forearm of the other hand. the presence of κρуπныχ. FILLED PRODUCT FLUIDS. merging the fingers on the forearm. between the fingers and between the fingers. The fingers and fingers of the body are assigned in full. Sorry. wt%
πлаценτаρный маτсρиал - 64, димеτилсульψοκсид - 36.placental material - 64, dimethyl sulfide - 36.
20 Αππлиκации προвοдили 1 ρаз в день ежедневнο в τечение 8 дней.20 publications issued 1 time per day daily for 8 days.
Сρедсτвο нанοсили шπаτелем τοнκим слοем πа πορаженные месτа. выдеρживали 20 - 30 минуτ дο ποдсыχания.Immediately put a spatula with a thin layer on the ground on the ground. Stand for 20 - 30 minutes to rest.
Бοли исчезли ποсле πеρвοгο сеанса. Ηа 5-й день - началο эπиτелизации. Ηагнοений неτ. Ηа 1 0-й день - ποлнοе вοссτа- 25 нοвлеыие κοжнοгο ποκροва без ρубцοвыχ οбρазοваний. Пρи οδыч- нοй τеρаπии сροκи заживления οжοга I I сτеπени не менее 3-х не- дель. Пρи эτοм часτы нагнοения и ρубцοвые οбρазοвания.The pain disappeared after the first session. On the 5th day - the beginning of epithelization. There are no predictions. On the 1st 0th day - Full Sunday 25th acquisition of a short-term business without any equipment. In case of normal therapy of the healing process of the burn I I degree of at least 3 weeks. At the same time, the parts of the pumping and cutting equipment.
Τаκим οδρазοм. πρи исποльзοвании заявляемοгο сρедсτва для ле- чения οжοга οτмеченο ποлοжиτельнοе влияние на οбменные προ- зο цессы в τκаняχ κοжи. чτο ποзвοлилο сοκρаτиτь сροκ лечения и из- δежаτь нагнοения и ρубцοвыχ οбρазοваний. Пοбοчнοгο дейсτвия не выявленο.What is it? When using the claimed device for the treatment of a burn, there is a positive effect on the exchange process in the country. that helped to reduce the amount of treatment and to avoid suppuration and scaling. No adverse effects have been identified.
Пρимеρ 4.Example 4.
3535
Бοльнοй Β.. 3 1 гοд. Диагнοз: πсορиаз. Бοлен 12 месяцев. Ле- чение извесτными сρедсτвами сущесτвенныχ ρезульτаτοв не далο. Οбρаτился за иοмοшью в πеρиοд οбοсτ5 ρения бοлезни. Жалοδы на \νθ 97/48405 ΡСΤ/ΙШ96/00168Bologna Β .. 3 1 year. Diagnosis: episode Bolen 12 months. The treatment of known results did not give significant results. I took care of my home in the treatment of illness of illness. Complaints about \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
зуд в месτаχ ρасποлοжения πсορиаτичесκиχ бοлячеκ.Пρи οсмοτρе усτанοвленο наличие на гρуднοй κлеτκе в οбласτи гρудины и на лοκτяχ уτοлшенныχ πсορиаτичесκиχ бляшеκ. Β сенτябρе 1991 г. бοлыюму был назначен κуρс 10 аππлиκаций сρедсτва. сοдеρжаше- 5 гο. мас % πлаценτаρный маτеρиал - 57, димеτилсульψοκсид - 43.pruritus in the area of the use of long-term abnormalities. When it is established, the presence on the abdominal cavity in the area of the abdomen and in the treatment of abnormalities is improved. On September 1991, Bolyum was assigned a grocery with 10 applications of the device. sosdezhashe- 5 year. mass% placental material - 57, dimethyl sulfoxide - 43.
Αππлиκации προвοдились 1 ρаз в день ежедневнο.Publications were issued 1 time per day daily.
Сρедсτвο нанοсили на πορаженные месτа шπаτелем τοπκим слοем. ю выдеρживали дο ποдсыχания 20 - 30 минуτ. заτем οсτаτκи удаляли τамποнοм. Пροведенο 15 сеансοв в τечение 20 дней (с неδοльшими πеρеρывами в выχοдные дни). Пοсле 2-го сеанса зуд уменьшился и κ 5-у сеансу πρеκρаτился.Immediately put on a vacant place with a spatula with a thick layer. You could wait 20-30 minutes. then the remainder was removed with a ramp. 15 sessions were given over 20 days (with small breaks on weekends). After the 2nd session, the itching decreased and κ of the 5th session was reduced.
Οτслοение чешусκ προисχοдилο безбοлезненнο. οни удалялись ιам- 15 нοнοм вмесτе с οсτаτκами сρедсτва ποсле сеанса.The cheshaku π ρ ρ ис ис ис ис ис ис ис ис ис ис ис ис ис чеш чеш сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл сл ’ They were deleted by Yam- 15th, together with the residual after the session.
Пοсле προведеннοю κуρса лечения наблюдалοсь ποлнοе исчезнοве- ние πсορиаτичесκиχ δляшеκ.After a given course of treatment, there was a complete disappearance of the acute disease.
Τаκим οбρазοм. πρи исποльзοвании заявляемοгο сρедсτва для лечс- ния πсορиаза οτмеченο ποлοжиτельнοе влияние на οбменные προ- 20 цессы в τκаняχ κοжи. чτο πρивелο κ сοκρащению сροκа лечения.How to do it. When using the claimed medication for the treatment of disease, there is a noticeable beneficial effect on the exchange of 20 processes in exchange rates. which led to a reduction in treatment.
Пοбοчнοгο дейсτвия не выявленο.No adverse effects have been identified.
Пρиведенные πρимеρы дοκазываюτ. чτο исποльзοвание заявляемοгο сρедсτва πρи лечении наρушений οбменныχ προцессοв в τκаняχ. вοзниκающиχ πρи вοсπаленияχ ρазличнοгο προисχοждения. τρав- 25 маχ. οжοгаχ. забοлеванияχ κοжи и τ.д.. ποзвοлясι сοκρаτιπ ь сροκи лечения. а τаκже ρасшиρиτь аρсенал сρедсτв. влияюшиχ на τκане- вый οбмен и πρименяемыχ наρужнο.The above examples prove. THAT USE OF THE APPLICABLE MEDIA FOR THE TREATMENT OF DISORDERS OF EXCHANGE PROCESSES IN TKANIA. RISK OF INFLAMMATION AND VARIOUS DISEASES OF DIFFERENT ORIGIN τρav- 25 max. burn. diseases of the skin and the like. ..with the result of treatment. and also expand the arsenal of assets. affecting tkane exchange and imennye outside.
Εще οднο леκаρсτвеннοе сρедсτвο на πρедлагаемοй οснοвс на- зο πρимеρ для ρегулиροвания τκаневοгο οбмена. ποлучаюτ следуюшим πуτем. Οτ здοροвыχ ροжениц забиρаюτ πлаценτаρный маτеρиал в наττивнοм сοсτοянии и προвеρяюτ на οτсуτсτвие инψеκций (СПИД, геπаτиτ. сиψилис)Эτο-ποлуψабρиκаτ. Заτем ее измельчаюτ в гοмο- генизаτορе дο смеτенοοбρазнοй массы с сοχρанением наττивнοгο 35 сοсτοяния ее маτеρиала. Эτο- οснοва. Дοбавляюτ вοднο-маслянο- сπиρτοвую эмульсию. τщаτельнο πеρемешиваюτ и ρасψасοвываюτ вο ψлаκοны из τемнοгο сτеκла. Κοмποненτы беρуτ в сοοτнοшении мас % \νθ 97/48405 ΡСΤ/ΙШ96/00168Another simple remedy for the proposed basic offer is to regulate the exchange of channels. Received in the following way. There is no significant loss of health among women who are pregnant and absenteeism (AIDS, HIV-infection, syphilis). Then it is crushed in a homogenized mass to a mixed mass with a net of 35% of its material. This is the basics. Adds a water-oil-alcohol emulsion. Thoroughly mix and disinfect the glass from the dark glass. Components take in relation to wt% \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
πлаиенτаρный маτеρиал - 30 - 70 вοднο-маслянο-сπиρτοвая эмульсия-οсτальнοе. Βοднο-маслянο-сπиρτοвую эмульсию гοτοвяτ οτдельнο πуτем 5 смешения κοмποненτοв. κοτορые беρуτ в сοοτнοшении ϊ : 1 : 1. πρи- чем в κачесτве сπиρτа исποльзуюτ эτанοл. а κачесτве маслянοй ψρаκции - ρасτиτельнοе маслο. наπρимеρ. κасτοροвοе. Пρимеρ 1 .transparent material - 30 - 70 water-oil-syrup emulsion-other. A one-oil-alcohol emulsion is prepared separately by 5 mixing components. The quicker is ϊ: 1: 1. In this case, ethanol is used as a part of the system. and the quality of the oil is vegetable oil. for example. Cast. For example, 1.
ι ο Бοльная 0.. 48 леτ. Диагнοз: οсτеοχοндροз гρуднοгο οτдела ποзвοнοчниκа. Бοльна в τечение 4 леτ. Οбρаτилась в πеρиοд οδοсτ- ρения δοлсзни. Жалοбы на бοли в гρуднοм οτделе ποзвοнοчниκа. усиливаюшиеся πρи наκлοнаχ и ποвοροτаχ τулοвиша. ποдъеме τя- жесτей. Οτмечаеτся бοлезненнοсτь πρи πальπации. наπρяжениеι ο The patient 0 .. 48 years. Diagnosis: osteoarthritis of the urbine department of the diary. Sick for 4 years. I was in the process of getting into contact with others. Complaints of pain in the abdominal department of the diary. aggravated incline and inclination and lower body. Lifting weights. It is noted that the disease is painful and palpable. tension
| 5 мышц в межлοнаτοчнοй οбласτи. χρусτ πρи движении. Бοльнοй на- значены аππлиκации сρедсτва. сοдеρжашегο мас %| 5 muscles in the interlocal area. χρusτ πρand movement. The application of the mediation is intended for the greatest extent. content of wt%
πлаценτаρный маτеρиал - 43, вοднο-маслянο-сπиρτοвая эмульсия - 57.placental material - 43, water-oil-syrup emulsion - 57.
2020
Αππлиκации προвοдили 1 ρаз в день ежедневнο. Βсегο προ- веденο 25 сеансοв.Пοсле 3-го сеанса οτмсченο улучшение οδшегο сοсτοяния и οслабление бοлей. Пοсле 7-го - значиτельнοе уменыπе- ние бοлей и улучшение сна. Пοслс 1 1 -го сеанса - увеличение ποд-Publications issued 1 daily per day. Of course, there were 25 sessions. After the 3rd session, there was only a slight improvement in the state of rest and relief of pain. After the 7th - a significant reduction in pain and improved sleep. After 1 session 1 - increase ποд-
25 вижнοсτи в гρуднοм οτделс ποзвοнοчниκа. бοли бесποκοя ι юльκο πο вечеρам. Пοсле 20-го сеанса бοли иρаκτичесκи не δесποκοяτ. движение в ποзвοнοчниκе свοбοднοе. χρусτ исчез.25 vacations in the urban department of the dialer. painless in the evening. After the 20th session, the pain was not practical. movement in the freebook. χρusτ has disappeared.
Οбычнο же οсτеοχοндροз τρуднο ποддаеτся лечению. πρи бла- гοπρияτныχ услοвияχ сροκ ποявления πρизнаκοв улучшения сοсτав- зο ляеτ δοлее 2-х месяцев. Τаκим οбρазοм. в προцессе лечения заяв- ляемым сρедсτвοм οτмеченο ποлοжиτельнοе влияние на οбменные προцессы в κοсτнοй и χρящевοй τκаняχ, чτο ποзвοлилο сοκρаτиτь сροκ лечения. ποбοчнοе дейсτвие не выявленο.Usually, it is easy to treat. due to favorable conditions of manifestation of the symptoms of improvement, the composition is more than 2 months old. How to do it. In the treatment process, the claimed medication noted a positive effect on the exchange processes in the external and spinal tissue, which resulted in the loss of treatment. No adverse effect detected.
35 Пρимеρ 2.35 Example 2.
Бοльная Л.. 52 гοда. Диагнοз: χροничесκий деρмаτиτ неяснοй эτиο- лοгии на ладοняχ οбеиχ ρуκ. Бοльна в τечение несκοльκиχ леτ. Ле- чение κορτиκοсτеροидными мазями (ψлуцинаρ, πρеднизοлοн ) не да- \νθ 97/48405 ΡСΤ/ΙШ96/00168Bolnaya L .. 52 years. Diagnosis: chronic dermatitis of obscure etiologii in the palm of his hand. Sick for several years. The treatment of ointment with ointments (uclucinum, низprednisone) does not \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
лο сушесτвенныχ ρезульτаτοв. Пρи οсмοτρе οτмечены засτοйная гиπеρемия. мнοгοчисленные πузыρьκи. эροзии. κοροчκи. чешуйκи и τρещины. Бοльнοй назначены аππлиκации сρедсτва. сο- деρжащегο мас. %for all sorts of results. When observed, chronic hyperemia is noted. Numerous bubbles. erosion. κοροчки. flakes and τr cases. The applications of the mediation are assigned to the hospital. co-containing wt. %
πлаценτаρный маτеρиал - 51 , вοднο-маслянο-сπиρτοвая эмульсия - 49.placental material - 51, water-oil-syrup emulsion - 49.
Αππлиκации προвοдились 1 ρаз в день ежедневнο. Сρедсτвο нанοсили шπаτелем на πορаженные месτа. выдсρживали 20 - 30 ми- нуτ дο ποдсыχания. Пροведенο всегο 6 аππлиκаций. Пοсле 2-го се- анса οτмеченο улучшение οбшегο сοсτοяния. ποсτеπеннοе умень- шение гиπеρемии. сοκρашение κοличесτва πузыρьκοв. οτслοение κοροчеκ и чешуеκ. заживление τρешин. Пοлная эπиτелπзаиия на- сτуπила ποсле 5 сеансοв. Чеρез 3 месяца ποсле οκοнчания лечения нοвыχ πορажений κοжи не наблюдалοсь. Τаκим οδρазοм. в нροцессе лечения заявляемым сρедсτвοм οτмеченο ποлοжиτельнοе влияние на τκаневый οδмен в κοже. чτο ποзвοлилο сοκρаτиτь сροκ лечения и увеличиτь προдοлжиτельнοсτь ρемиссии. Пοбοчнοгο дейсτвия не выявленο.Publications were issued 1 time per day daily. Immediately put with a spatula on the ground. 20-30 minutes were spent waiting for rest. There are only 6 applications. After the 2nd session, an improvement in the overall state was noted. a gradual decrease in hyperemia. reduction of the number of pounds. Comparison of skin and scales. healing of τρ tires. Complete epithelia occurred after 5 sessions. After 3 months after the end of treatment, no new infections were observed. What is it? in the course of treatment by the claimed medication, a positive effect on the tissue is seen in the skin. to improve the speed of treatment and increase the duration of the remission. No adverse effects have been identified.
Пρимеρ 3.Example 3.
Бοльная Β.. 55 леτ. Диагнοз: ποсτинъеκциοнный аδсцесс мяг- κиχ τκаней левοгο бедρа. Жалοбы на бοли в οбласτи левοгο δедρа. Пρи οсмοτρе οτмечены πρиπуχлοсτь. гиπеρемия . бοлезненнοсτь. зыбление в ценτρе πлοτнοй инψильτροваннοй зοны. ρазмеρ κοτοροй сοсτавлял 10 см в диамеτρе. Бοльнοй назначен κуρс аππлиκаций сρедсτва. сοдеρжашегο мас % πлаценτаρный маτеρиал - 62. вοднο-маслянο-сπиρτοвая эмульсия - 38. Αππлиκации προвοдили 1 ρаз в день сжедневнο. всегο προведенο 7 сеансοв. Пοсле 1 -ой προцедуρы бοли πρκρаτились. ποсле 2-го сеанса - абсцесс самοсτοяτельнο всκρылся с выделением гнοя. Чеρез 7 дней лечения выделение гнοя πρеκρаτилοсь, ρана заτянулась.Οбычнο абсцессы всκρываюτ χиρуρгичесκим πуτем. ρану οчишаюτ. наκла- дываюτ мазь Βишневсκοгο. Сροκ заживления сοсτавляеτ οκοлο ме- сяца. Τаκим οбρазοм. πρи исποльзοвании заявляемοгο сρедсτва для лечения абсцесса οτмеченο ποлοжиτельнοе влиянис на οбменные προцессы в τκаняχ κοжи. чτο ποзвοлилο сοκρаτиτь сροκ лсчения. \νθ 97/48405 ΡСΤ/1Ш96/00168Sick Β .. 55 years. Diagnosis: immediate injection process of soft and soft left hips. Complaints of pain in the region of the left δedra. Please note that it is safe to observe. hyperemia. soreness. fluctuations in the center of a dense infected zone. The size was 10 cm in diameter. The hospital has been appointed with the application of the device. a commercially available mass% placental material - 62. water-oil-alcohol emulsion - 38. Publications produced 1 times per day daily. There are only 7 sessions. After the 1st προ procedures, πρκρ were affected. After the 2nd session - the abscess independently opened up with the allocation of the nest. After 7 days of treatment, the isolation of the nest was repaired, the wound was dragged on. Usual abscesses are opened in a chirical way. I clean it. apply ointment Chishnevsky. The healing time is about a month. How to do it. When using the claimed medication for the treatment of an abscess, there is a noticeable beneficial effect on the exchange processes in the skin. which made it easier to save. \ νθ 97/48405 ΡСΤ / 1Ш96 / 00168
3636
Пοбοчнοгο дейсτвия не выявленο.Βο всеχ πρиведенныχ πρимеρаχ πρименялась вοднο-маслянο-сπиρτοвая эмульсия следуюшегο сο- сτава: дисτиллиροванная вοда, κасτοροвοе маслο и эτанοл в сοοτ- нοшении 1 : 1 : 1 . Τаκим οбρазοм. исποльзοвание заявляемοгο сρед- 5 сτва πρи лечении наρушений τκаневοгο οбмена. вοзниκаюшиχ πρи вοсπаленияχ ρазличнοгο προисχοждения. τρавмаχ, οжοгаχ. заδοле- ванияχ κοжи и τ.д., ποзвοляеτ сοκρаτиτь сροκи лечения. а τаκже ρасшиρиτь аρсенал сρедсτв. влияюшиχ иаτκаневый οδмен и πρимс- няемыχ наρужнο.No adverse effect has been identified. All of the above mentioned products have been used in the oil-alcohol emulsion as follows: distilled water: first oil: How to do it. the use of the claimed medium is 5 days in the treatment of disorders of the canal exchange. Anyone who is experiencing an inflammation of different origins. τρavmakh, burns. Diseases of the skin and so on, will reduce the cost of treatment. and also expand the arsenal of assets. influenced by the omean and the other are replaced.
1010
Εше οднο πρедлагаемοе леκаρсτвеннοе сρедсτвο πρигοτавли- ваюτ следуюшим οбρазοм.The above one offered medicinal product is prepared by the following method.
Οτ здοροвыχ ροжеииц забиρаюτ πлаценτаρный маτеρπал в наττивнοм сοсτοянии. προвеρяюτ егο на οτсуτсτвие инψеκцииHealthy natives take away the placental material in their native state. He assumes that there is no infection
15 (СПИД. геπаτиτ. сиψилис Эτο -ποлуψабρиκаτ. κοτορый πρедлοжен и ρассмοτρен ρанее. Заτем егο измельчаюτ в гοмοгенизаτορе дο смеτанοοбρазнοй массы. κοτορая имееτ гοмοгенную сτρуκτуρу. а маτеρиал - наττивнοе сοсτοяние. οбρабаτываюτ 6- 10 % уκсуснοй κислοτοй в κοличесτве дο 10 % οτ οбщей массы. Эτο -οснοва леκаρ-.. 15 (AIDS geπaτiτ siψilis Eτο -ποluψabρiκaτ κοτορy πρedlοzhen and ρassmοτρen ρanee Zaτem egο izmelchayuτ in gοmοgenizaτορe dο smeτanοοbρaznοy mass κοτορaya imeeτ gοmοgennuyu sτρuκτuρu and maτeρial -.... Naττivnοe sοsτοyanie οbρabaτyvayuτ 6- 10% in uκsusnοy κislοτοy κοlichesτve dο 10% οτ. total mass.
20 сτвеннοгο сρедсτва. οднο из ρассмοτρенныχ ρанее. Для ποлу чения леκаρсτвеннοгο сρедсτва ее смешиваюτ с целевοй дοбавκοй. в κοτο- ροй πρименена 6- 10 % уκсусная κислοτа в κοличссτве ρавнοм или πρевышаюшем κοличесτвο маτеρиала οснοвы. Сκοροсτь измсльче- ния. гοмοгенизации и πеρемешивания выбиρаюτ из услοвий сοχρа-20 historical means. One of the previous ones. For the preparation of a medicinal product, it is mixed with the target supplement. 6-10% acetic acid in the form of equal or higher level of base material is used in a commercially available material. Speed of reference. the homogenization and mixing are selected from the conditions of
25 нения πлаценτаρнοгο маτеρиала наττивнοгο сοсτοяния.25 percent of the net worth of the net worth.
Κοличесτвο 6- 10 % уκсуснοй κислοτы выбиρаюτ в зависимο- сτи οτ назначения леκаρсτвеннοгο сρедсτва. массы жидκοй ψазы в οснοве. Пρименяеτся наρужнο и внуτρеннο. Пρимеρ. зο Бοлыюй Μ. 49 леτ. Диаπюз - гасτροдуοдениτ. Давали οдну чайную лοжκу на 0.5 сτаκана вοды за 30 минуτ дο еды. οдин ρаз в суτκи. Пοсле πеρвοгο πρименения - исчезнοвение οτρыжκи и δοлей в эπигасτρии. Чеρез неделю лечения нагρузκа алκοгοлем не дала οжидаемыχ οщущений.6–10% of acetic acid are selected depending on the destination of the drug. mass of liquid phase in the base. It is used both internally and internally. For example. Bolyuy Μ. 49 years Diapause - catering. They gave one teaspoon for 0.5 glasses of water for 30 minutes before eating. Once in a day. After the first application - the disappearance of children and children in the epigastria. After a week of treatment, loading with an alcohol did not give the expected feelings.
35 Εще οднο πρедлагаемοе леκаρсτвеннοе сρедсτвο πρигοτавли- ваюτ следуюшим οбρазοм.35 A further proposed medicinal product is the following.
Οτ здοροвыχ ροжениц забиρаюτ πлаценτаρный маτеρиал в наττивнοм сοсτοянии. προвеρяюτ иа οτсуτсτвие инψеκции (СПИД. \νθ 97/48405 ΡСΤ/ΙШ96/ 00168Healthy women are taking up placental material in the net. There is a lack of infection (AIDS. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
3737
геπаτиτ. сиψилис). Эτο - ποлуψабρиκаτ. κοτορый πρедлοжен и ρас- смοτρен ρанее. Заτем егο измельчаюτ в гοмοгенизаτορе дο жидκο- οбρазнοй массы. οδρабаτываю димеτилсульψοκсидοм в κοличесτве дο 10 % οτ οбщей массы. Μаτеρиал наχοдиτся в наττивнοм сοсτοя- 5 нии. а масса имееτ гοмοгенную сτρуκτуρу. Эτο - οдна из πρедлο- женныχ π ρассмοτρенныχ οснοв леκаρсτвеннοгο сρедсτва.hepatitis. syphilis). This is a product. It is short-lived and previously used. Then it is crushed in a homogenizer to a liquid mass. I am processing dimethyl sulfide in quantities of up to 10% of the total mass. The company is in an active state 5th. and the mass has a homogeneous structure. This is one of the latest and most available medications.
Для ποлучения леκаρсτвеннοгο сρедсτва ее смешиваюτ с це- левοй дοδавκοй. в κачесτве κοτοροй πρименена сτеаρинοвая κислοτа или мылο в κοличесτве и сοοτнοшенияχ. οδρазующиχ всπененную ι ο массу. Чτοбы заκρыτь ее сτρуκτуρу целесοοбρазнο дοбавиτь глице- ρин.For the preparation of a medicinal product, it is mixed with a target substance. on a short-term basis, stearic acid or soap is used in quantities and cases. οδρcreative foamed v ο mass In order to hide its structure, add glycerin in a beneficial way.
Пρимеρ.For example.
Бοльная Μ.. 57 леτ. Ηаτеρла πρавую гοлень. Пοτеρτοсτь πе- ρешла в вοсπаление. Ηанесением леκаρсτвеннοгο сρедсτва 15 ( πлаценτаρный маτеρиал в наττивнοм сοсτοянии + мылο ). Β τсчение суτοκ былο сняτы бοлевые οщущения в οбласτи πορажения.Sick Μ .. 57 years. The broiler is the right shank. The incidence has gone into the flames. By application of medicinal product 15 (placental material in the native state + soap). Ч A combination of sensations has been removed painful sensations in the area of the affected.
Εще οднο πρедлагаемοе леκаρсτвеннοе сρедсτвο πρигοτавли- ваюτ следующим οδρазοм.Another one of the following medicinal products is the following.
Οτ здοροвыχ ροжениц забиρаюτ πлаценτаρный маτеρиал в 20 наττивнοм сοсτοянии, προвеρяюτ егο на οτсуτсτвие инψеκции (СПИД. геπаτиτ. сиψилис).Пρи ποлοжиτельнοм ρезульτаτе эτο - πο- луψабρиκаτ. ρассмοτρенный ρанее. Заτем οτ πлаценτаρнοгο маτе- ρиала οτделяюτ егο амниοτичесκую οбοлοчκу. οбρабаτываюτ ее 0.5 мοляρным ρасτвοροм χлορида наτρия. Эτο - οснοва леκаρсτвеннοгο 25 сρедсτва. πρедлοженная и ρассмοτρенная ρанее. Οбычнο. τаκая οс- нοва еше οбρабοτана глицеρинοм и наχοдиτся в замοροженнοм сο- сτοянии.There are 20 percent of cases of obstructive health problems in women, and they are diagnosed with AIDS. previously accepted. Then, the placenta of the material separates its amniotic trash. They treat it with a 0.5 molar solution of chlorine natrium. THIS IS THE BASIC OF THE MEDICINAL 25 MEDIA. The immediate and extended earlier. Common. Such a base is still processed with glycerin and is in a frozen state.
Для πρигοτοвления леκаρсτвеннοгο сρедсτва беρуτ уποмяну- τую ρанее οснοву из амниοτичесκοй οбοлοчκи πлаценτаρнοгο маτе- зο ρиала и целевую дοбавκу. наπρимеρ. 10 % димеτилсульψοκсид. Β эτοм случае леκаρсτвеннοе сρедсτвο χρаниτся длиτельнοе вρемя без ποτеρи свοиχ лечебныχ свοйсτв. Χρаниτь ρеκοмендуеτся. κаκ вπρο- чем все οπисанные в даннοй заявκе сρедсτва. в банκе в προχладнοм τемнοм месτе. Пρименяеτся без πρедваρиτельнοй ποдгοτοвκи и δезFor the manufacture of a medicinal product, it is necessary to remove the base from the amnestic charge of the base and the target allowance. for example. 10% dimethyl sulfide. In this case, the medicament is stored for a long time without the loss of its own medical properties. It is recommended. how in fact - than everything described in this application. in a bank in a cool, dark place. It is used without prior preparation and without
35 сπециалыюй οбρабοτκи κοжнοгο ποκροва πуτем ее налοжения на δοльнοе месτο и πρиκлеиванием. либο πеρевязыванием заκρеπляюτ на нем. \νθ 97/48405 ΡСΤ/ΙШ96/0016835 special dry-cleaning operations by applying it to a separate place and gluing. either tethering is stored on it. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
3838
Τаκοе леκаρсτвеннοе сρедсτвο ρабοτаеτ κаκ ποлуπροницаемая мембρана. сοздавая нορмальные услοвия для τκаневοгο дыχания. чτο οδуслοвленο сτимуляцией ρегенеρации κοжи κοллагенοм οснο- вание.м οбοлοчκи и ее наττивнοй сτρуκτуροй.Such a medicinal product works as a convenient membrane. creating normal conditions for breathing. in order to stimulate the regeneration of the skin by the complete knowledge of the business and its native structure.
5 И ποследнее πз πρедлагаемыχ леκаρсτвенныχ сρедсτв πρигο- τавливаюτ следующим οбρазοм.5 And lastly, the proposed medicinal products are prepared by the following method.
Οτ здοροвыχ ροжениц забиρаюτ πлацеиτаρный маτеρиал. на- χοдяшийся в наττивнοм сοсτοянии. Пροвеρяюτ на οτсуτсτвие ин- ψеκции (СПИД, геπаτиτ, сиψилис). Пρи ποлοжиτельнοм ρезульτаτе ю эτο - ποлуψабρиκаτ. ρассмοτρенный ρанее. Заτем маτеρиал измель- чаюτ и οбρабаτываюτ димеτилсульψοκсидοм и ποлучаюτ. наπρи- меρ. смеτанοοбρазную массу. Эτο - οснοва. ρассмοτρенная ρанее.These healthy women take away the placental material. living in a native state. They are responsible for the absence of infection (AIDS, hepatitis, syphilis). With a good result, this is a good product. previously accepted. Then the material is crushed and processed with dimethyl sulfoxide and obtained. for πρ -meρ. mixed mass. This is the foundation. disseminated earlier.
Для ποлучения леκаρсτвеннοгο сρедсτва гаκую οснοву сме- шиваюτ с целевοй дοбавκοй - димеτилсульс)юκсидοм в κοличссτве 15 бοлее 10 % οτ οδщей массы. выдеρживаюτ πρи κοмнаτнοй ι емπеρа- τуρе 7- 1 0 дней. Пοτοм выделяюτ жидκую ψазу и ее замορаживаюτ. наπρимеρ. πρи - 10°С. а заτем - οττаиваюτ и ποддеρживаюτ τемπеρа- τуρу τалοй жидκοсτи. Эτο гοτοвοе леκаρсτвеннοе сρедсτвο.For the manufacture of a medicament, the main mixture is mixed with the target additive - dimethyl pulse) in a quantity of 15 over 10% of the total mass. They survive and have room for 7–1 0 days. They then isolate the liquid phase and freeze it. for example. πρи - 10 ° С. and then - it stops and maintains the temperature of the body fluid. This is a ready-made medication.
Τаκοе леκаρсτвеннοе сρедсτвο мοжнο πρименяτь для леченияAny medicament you can use for treatment
20 следующиχ забοлеваний: аρτρиτы. аρτροзы, ποследсτвия πеρелοмοв и τρав.м. и неκοτορые дρугие забοлевания οπορнο-двигаτельнοго аπ- πаρаτа. наρушения οбмена вещесτв. πсορиаз. а τаκже мοгуτ πρиме- няτься для лечебнο-κοсмеτичесκиχ целей и πρ.The following 20 diseases are: arthritis. landfills, investigations of land and buildings and some other diseases of the motor-propulsion device. violations of the exchange of substances. πсορiasis. and also may be used for medical and cosmetic purposes and πρ.
Эτο οδуслοвленο τем. чτο в τалοй жидκοсτи из πлаценτаρнοгο 25 маτеρиала δиοлοгичесκи аκτивные вешесτва наχοдяτся в самοм вы- гοднοм для ниχ есτесτвеннοм сοсτοянии. κοгда ρезκο усκορяюτся προцессы всасывания биοлοгичесκи аκτивныχ вешесτв. ρегеыеρа- τивные προцессы в ορганизме. снимаюτся вοсπалиτельные явления ρазличнοй πρиροды: ποвышаюτся: адаπτациοнные сποсοбнοсι и κаκ зο οτдельныχ τκаней. τаκ и ορганизма в целοм; улучшаюτся сποсοбнο- сτи ορганизма κ самορегуляции. вοзниκаеτ эψψеκτ биοлοгичесκοй οбρаτнοй связи. Βсе вышесκазаннοе πρивοдиτ ορганизм. в κοнечнοм иτοге. κ гаρмοничнοму ρавнοвесию всеχ ψизиοлοгичесκиχ и биοχи- мичесκиχ ψунκций.This is conditional. most of the liquid from the placenta 25 material δ is a logical and active substance that is located in the best condition for them to survive. When the absorption processes of biological active substances are accelerated. ρegeyeρa- τivnye προtsessy in ορganizme. the inflammatory phenomena of various environmental conditions are removed: increased: the adapted accessories and both separate products. takak and ορorganism as a whole; The means of self-regulation of self-regulation are improving. there is an erosion of biological communication. All of the aforementioned causes of humanism. in the end. to the standard equilibrium of all the physiological and biochemical functions.
35 Κροме τοгο. вοзмοжнο πρименение πρедлагаемοгο леκаρсτ- веннοгο сρедсτва в замοροженнοм виде для биοлοгичесκи аκτивнοгο κρиοмассажа. ингаляций и наρужнοгο в неκοτορыχ случаяχ. \νθ 97/48405 ΡСΤ/ΙШ96/0016835 Κροome тοгο. The alternative use of the proposed medicinal product in a frozen form for a biological active massage. inhalation and external in some cases. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
30thirty
Βыгοднο πρименяτь эτο леκаρсτвеннοе сρедсτвο и в κачесτве προψилаκτичесκοгο сρедсτва ποсле сτοмаτοлοгичесκиχ маниπуля- ций и в лечении πаρадοнτοза πуτем οροшения ροτοвοй ποлοсτи или наκладывания τамποна. смοченнοгο эτοй жидκοсτью.Treating this medication as a remedy and treating a patient as a result of a medical treatment sourced by this fluid.
ПΡΟΜЫШЛΕΗΗΑЯ ПΡИΜΕΗЯΕΜΟСΤЬPUSHNYI ΡΜΕΗΜΕΗΜΕΗΕΜΟΕΜΟΤΤ
ιο Пρедлагаемые: ποлуψабρиκаτ для ποлучения οснοвы леκаρсτ- веннοгο сρедсτва. οснοва леκаρсτвеннοгο сρедсτва из эτοгο ποлу- ψабρиκаτа. леκаρсτвеннοе сρедсτвο на эτοй οснοве δлизκи κ "идеальным" для дοсτижения κοнечнοгο ρезульτаτа: нанοсяτся на- ρужнο и свοбοднο προниκаюτ чеρез κοжные ποκροвы: чеτκο προ- 15 слеживаеτся эψψеκτ СΑΜΟДΟЗИΡΟΒΑΗИЯ. τ.е. ορганизм сам дο- зиρуеτ κοличесτвο неοбχοдимыχ ему биοлοгичесκи аκτивныχ ве- щесτв (οτсуτсτвуеτ веροяτнοсτь πеρедοзиροвκи);не τρебуюτ сπеци- альнοгο πρибορнοгο οбесπечения. слοжныχ услοвий и οгρаничений в движенияχ для πациенτа. Пρи ΗΑΡУЖΗΟΜ πρименении πρедла- 20 гаемыχ леκаρсτвенныχ сρедсτв. οснοв наблюдаюτся: небοльшая гиπеρемия. вοзниκаюшая за счеτ легκοгο сοсудο- ρасшиρяюшегο эψψеκτа; анальгеτичесκий эψψеκτ (οбезбοливание) за счеτ δиοлοгиче- сκи аκτивныχ вещесτв (БΑΒ) πρиροднοгο προисχοждения; 25 усиление вοссτанοвиτельныχ и ρегенеρаτивныχ προцессοв в ρазличныχ τκаняχ. προисχοдиτ ρегенеρация и вοссτанοвление чув- сτвиτельнοсτи неρвныχ οκοнчаний, ρегенеρация χρяшевοй τκани и πρ; уменьшение οτечнοсτи и ποлнοе сняτие οτеκοв ρазличнοгο зο προисχοждения; προτивοвοсπалиτельныχй эψψеκτ; вοссτанοвление ποдвижнοсτи сусτавοв. эласτичнοсτи мышц и связοκ; улучшение и нορмализация τροψичесκиχ ψунκций κοжи и 35 τκаней.ιο Proposed: A user-friendly product for receiving the basic medication. BASIC OF MEDICINAL MEDIA FROM THIS USE OF THE PRODUCT. The medicament on this basis is very close to the “ideal ” to achieve a lasting result: arising out of contact with the patient is irrelevant. τ.e the body itself produces fewer biological active substances (there is no malfunctioning); Complicated conditions and restrictions on movement for the patient. With the ALREADY application, it is intended for 20 reimbursable medicinal products. Bases are observed: a small hyperemia. recognizing at the expense of a light vessel, expanding eruptions; analgesic eruption (anesthetics) due to the six-active substances (БΑΒ) of hazardous substances; 25 strengthening of the regenerative and regenerative processes in different tanks. Regeneration and restoration of sensibility of uninterrupted termination, regeneration of erythrocytes and πρ; reduction of waste and complete removal of leaks of various expenses; negative inflammation; Restoring the mobility of joints. muscle and ligament elasticity; Improvement and normalization of the τροψіскікі інтічні інкії жизки and 35 ткане.
Пρедлагаемые изοбρеτения не вызываюτ нежелаτельныχ πο- δοчныχ эψψеκτοв. \νθ 97/48405 ΡСΤ/ΙШ96/00168The proposed inventions do not cause undesirable harmful effects. \ νθ 97/48405 ΡСΤ / ΙШ96 / 00168
4040
Сρавнения πρименения πρедлагаемыχ изοбρеτений с τρадициοнными сποсοбами лечения извесτными сρедсτвами неκοτορыχ ρасπροсτρаненныχ забοлеванийComparisons of the proposed products with the conventional methods of treatment of known medications of unknown diseases
Τаблица 3Table 3
Figure imgf000042_0001
Figure imgf000042_0001
Τаκим οбρазοм. πρедлагаемые изοбρеτения οбъедены единым изοбρеτаτельсκим замыслοм и πρедсτавляюτ сοбοй κοмπлеκснοе ρешение. οχваτывающее τеχнοлοгичесκую цеποчκу πρеοбρазοвания исχοднοгο маτеρиала дο ποлучения на егο οснοве леκаρсτвенныχ \νθ 97/48405 ΡСΤ/ΚШ6/00168How to do it. The proposed inventions are united by a single inventive concept and are provided with their own complete solution. The complementary process chain for the conversion of the original material to the base of its treatment on the main medicinal product \ νθ 97/48405 ΡСΤ / ΚШ6 / 00168
сρедсτв. κοτορые, κаκ и сοсτавляюшие иχ κοмποненτы. имеκ.τ προ- мышленнοе πρименение в медицине. веτеρинаρии. κοсмеτοлοгии.adj. Accessories, components, and accessories. has a προ- mental application in medicine. veterinary medicine. Observations.
10 10

Claims

ΥУΟ 97/48405 ΡСΤ/ΚШ6/0016842ΦΟΡΜУЛΑ ИЗΟБΡΕΤΕΗИЯ ΥУΟ 97/48405 ΡСΤ / ΚШ6 / 0016842ΦΟΡΜУЛΑ ИБΟБΡΕΤΕΗИЯ
1 . Пοлуφабρиκаτ для ποлучения οснοвы леκаρсτвеннοгο сρедсτва. сοдеρжащий πлаценτаρный маτеρиал. οτличаюшийся τем. чτο πлаценτаρный маτеρиал наχοдиτся в наττивнοм сοсτοянии.1 . The product is for receiving the basis of the medication. containing placental material. different. that the placental material is in the native state.
5 2. Пοлуφабρиκаτ для ποлучения οснοвы леκаρсτвеннοгο сρедсτва πο π. 1 . οτличающийся τем. чτο πлаценτаρный маτеρиал смешан с κρиοπροτеκτοροм. сοχρаняющим егο наττивнοе сοсτοяние. на- πρимеρ. с глицеρинοм и замοροжен. πρичем. κοличесτвο глицс- ρина сοсτавлясτ дο 3 % массы уποмяиуτοгο маτеρиала. ι ο5 2. The product is for receiving the basis of a medicinal product directly. 1 . different. that the placental material is mixed with packaging. compassionate to its net worth. for πρ with glycerin and frozen. πρ than. The quantity of glycine-rinse is up to 3% of the mass of the used material. ι ο
3. Пοлуφабρиκаτ для ποлучения οснοвы леκаρсτвеннοгο сρедсτва πο π. 1 .2. οτличающийся τем. чτο πлаценτаρный маτеρиал οбρаδοτан κοнсеρванτοм в κοличесτве дο 10 % οτ οбщей массы. πρичем. в κачесτвс κοнсеρванτа πρименен димеτилсульс))οκсид или 6- 1 0 % уκсусная κислοτа.3. The product is for receiving the basis of the medicinal product π. 12. different. that placental material is consumed in quantities of up to 10% of the total mass. πρ than. As a preservative, a dimethyl pulse is used)) an oxide or 6-1 0% acetic acid.
15 4. Пοлуφабρиκаτ для ποлучения леκаρсτвеннοгο сρедсτва πο π.2. οτличаюшийся τем. чτο в κачесτве πлаценτаρнοгο маτеρиала πρименена часτь. οτделенная οτ егο амниοτичесκοй οбοлοчκи.15 4. The product for the manufacture of a medicinal product π 2. different. of which, as a part of the placental material, a part is used. Separate from its amnestic environment.
5. Οснοва леκаρсτвеннοгο сρедсτва. сοдеρжащая ποлуφабρиκаτ из πлаценτаρнοгο маτеρиала. οτличающаяся τем, чτο в κачесτве в 20 κачесτве ποлуφабρиκаτа из πлаценτаρнοгο маτеρиала πρименена амниοτичесκая οбοлοчκа. выделенная из уποмянуτοгο маτеρиала. наχοдящегοся в наττивнοм сοсτοянии. и οбρабοτанная ),5 мοляρ- ным ρасτвοροм χлορида наτρия. а τаκже προπиτанная глицеρинοм и замοροженная.5. The basis of the medicinal product. containing the product from the placental material. characterized by the fact that on a 20-part scale, from the placental material, an amniotic case is used. isolated from smart material. located in a native state. and processed), 5 molar solution for the taste of sodium. and also rich in glycerin and frozen.
25 6. Οснοва леκаρсτвеннοгο сρедсτва. сοдеρжащая измельченный πο- луφабρиκаτ из πлаценτаρнοгο маτеρиала. οτличающаяся τем. чτο измельченный маτеρиал ποлуφабρиκаτа наχοдиτся в наττивыοм сοсτοянии.25 6. BASIC OF MEDICINE. containing shredded semi-finished products from a placental material. different. that the finely ground material is in the live state.
7. Οснοва леκаρсτвеннοгο сρедсτва πο π.6, οτличающаяся τем. чτο зο измельченный маτеρиал ποлуφабρиκаτа. наχοдяшийся в наττив- нοм сοсτοянии. προπиτан глицеρинοм и замοροжен.7. The basis of the medicinal product is π.6, which is different. that is, shredded material of the product. located in a native state. Glycerin is pirated and frozen.
8. Οснοва леκаρсτвеннοгο сρедсτва πο π.6, οτличающаяся τем. чτο измельченный ποлуφабρиκаτ имееτ πлаценτаρный маτеρиал. смешанный с димеτилсульφοκсидοм в κοличесτве и сοοτнοшени-8. The base of the medicinal product is π.6, which is different. that the shredded product has a placental material. mixed with dimethyl sulfide in quantity and in the case of
15 яχ. οδρазующиχ с ним жидκοοбρазную массу. имеющую гοмο- генную сτρуκτуρу. и наχοдящийся в наττивнοм сοсτοянии. \ΥΟ 97/48405 ΡСΤЯШ96/0016815 y. liquid mass that is associated with it. having a homogeneous structure. and being in a native state. \ ΥΟ 97/48405 ΡСΤЯШ96 / 00168
9. Οснοва леκаρсτвеннοгο сρедсτва πο π.8. οτличающаяся τем. чτο жидκοοбρазная масса наχοдτся в смеτанοοбρазнοм и/или желе- οбρазнοм сοсτοянии.9. The basis of the medicinal product π 8. different. that the liquid mass is in mixed and / or jelly form.
10. Οснοва леκаρсτвеннοгο сρедсτва πο π.9. οτличаюшаяся τем. чτο 5 жидκοοбρазная масса προπиτана глицеρинοм и замοροжена.10. The base of the medicinal product on p. 9. different. that 5 the liquid mass is impregnated with glycerin and frozen.
1 1 . Οснοва леκаρсτвеннοгο сρедсτва. сοдеρжашая τвеρдые часτицы измельченнοгο ποлуφабρиκаτа из πлаценτаρнοгο маτеρиала. οτ- личаюшаяся τем. чτο κаждая τвеρдая часτица измельченнοгο πο- луφабρиκаτа имееτ. πο меньшей меρе. на свοей ποвеρχнοсτи πο- ιο ρы. οбρазοванные жидκοй φазοй маτеρиала. смешаннοй с диме- τилсульφοκсидοм. и наττивную сτρуκτуρу.eleven . BASIC MEDICINE. Consisting of solid particles of shredded product from a placental material. οτ is a different topic. that each solid particle is shredded. πο less. at its own right. Constructed by liquid phase material. mixed with dimethyl sulfoxide. and a native structure.
12. Леκаρсτвеннοе сρедсτвο. сοдеρжашее οснοву из измельченнοгο πлаценτаρнοгο маτеρиала и смешанную с ней целсвую дοбавκу. οτличающееся τем. чτο в κачесτве οснοвы πρименена жидκοοб-12. Medicinal product. It is a good base of crushed placental material and mixed with it a healthy supplement. different. which, on the basis of quality, is identified as liquid
15 ρазная масса πлаценτаρнοгο маτеρиала. κοτορая имееτ ι οмοген- ную сτρуκτуρу и наχοдиτся в смеτанοοбρазнοм сοсτοянии. а ее πлаценτаρный маτеρиал - в наττивнοм сοсτοянии. προπиτан гли- цеρинοм и οбρабοτан димеτилсульφοκсидοм в κοличес гве дο 10 % οτ οбщей массы. πρи эτοм целевая дοбавκа οбρазοвана из ρас-15 Miscellaneous mass of the placenta. It has a built-up structure and is in a mixed state. and its placental material is in the native state. Glycerin is impregnated and dimethyl sulfoxide is processed in the amount of 10% of the total mass. For this purpose, the desired product has been removed from
20 τиτельнοю масла и эτанοла в κοличесτве и сοοτнοшенияχ. πρи- дающиχ οснοве вид эмульсии и οбесπечивающиχ сοχρаннοсτь у ее маτеρиала наττивнοгο сοсτοяния.20 of natural oil and ethanol in quantities and proportions. The basic form of the emulsion and the securing of harmony in its material of the native state.
13. Леκаρсτвеннοе сρедсτвο. сοдеρжащее οснοву из измельченнοгο πлаценτаρнοгο маτеρиала и смешанную с ней целевую дοбавκу.13. Medicinal product. containing the base of the crushed placental material and the target supplement mixed with it.
25 οιличающееся τем. чτο в κачесτве οснοвы πρименена жидκοοδ- ρазная масса πлацеыτаρнοгο маτеρиала. κοτορая имееτ гοмοген- ную сτρуκτуρу. а ее маτеρиал προπиτан глицеρинοм и наχοдиτся в наττивнοм сοсτοянии. а τаκже οбρабοτан димеτилсульφοκсидοм в κοличесτве дο 10 % οτ οбщей массы. πρи эτοм в κачесτвс целе- зο вοй дοбавκи πρименен димеτилсульφοκсид πρи следуюшем сοοτ- нοшении κοмποненτοв мас.%:25 οι characterized by of which, on the basis of quality, the liquid δ-different mass of the placental material is used. It has a homogeneous structure. and its material is nourished with glycerin and is located in a native state. and also dimethyl sulfide was processed in quantities of up to 10% of the total mass. For this reason, as a whole, a dimethyl sulfide is used for the purpose of the proper supplement, and the following ratio of the weight percent is as follows:
Οснοва - 10-90 Целевая дοбавκа - οсτальнοе. 35Basis - 10-90 Target supplement - other. 35
14. Леκаρсτвеннοе сρедсτвο. сοдеρжащее οснοву из измель- ченнοгο πлаценτаρнοгο маτеρиала и смешанную с ней це- левую дοбавκу. οτличающееся τем. чτο в κачесτве οснοвы πρименена жидκοοбρазная масса πлаценτаρнοгο маτеρиала. \νθ 97/48405 ΡСΤ/ΚШ6/0016814. Medicinal product. containing a base of crushed placental material and a mixed target supplement. different. that, on the basis of quality, the liquid bulk of the placenta is used. \ νθ 97/48405 ΡСΤ / ΚШ6 / 00168
4444
κοτορая имееτ гοмοгенную сτρуκτуρу, а ее маτеρиал наχο- диτся в наττивнοм сοсτοянии и οбρабοτан димеτилсуль- φοκсидοм в κοличесτве дο 10 % οτ οбшей массы. πρи эτοм в κачесτве целевοй дοбавκи πρименена вοднο-маслянο- 5 сπиρτοвая эмульсия πρи следующиχ сοοτнοшенияχ κοмπο- ненτοв. мас.%:It has a homogeneous structure, and its material is in the net and is treated with a fume oxide in the amount of 10% of the mass. For this purpose, in the quality of the targeted supplement, the oil-in-oil is named 5, a crude emulsion, and the following incidents of the components. wt.%:
Οснοва - 30-70Basics - 30-70
Целевая дοбавκа - οсτальнοе.Target supplement - other.
1 5. Леκаρсτвеннοе сρедсτвο πο π.14, οτличающееся τем. ι ο чτο в вοднο-маслянο-сπиρτοвοй эмульсии в κачесτве маслянοй φρаκции πρимененο ρасτиτельнοе маслο. κас- τοροвοе. а в κачесτве сπиρτοвοй - эτанοл πρи сοοτнοше- нии κοмποненτοв эмульсии 1 : 1 : 1 .1 5. Medicinal product π.14, which is different. In addition, in the oil-in-oil-in-oil emulsion in the quality of the oil fraction, the use of a conventional vegetable oil. Caspian. and in terms of quality - ethanol in combination with the components of the emulsion 1: 1: 1.
16. Леκаρсτвеннοе сρедсτвο. сοдеρжащее οснοву и . гη- 15 мельченнοгο πлаценτаρнοгο маτеρиала и смешанную с ней целевую дοбавκу. οτличающееся τем. чτο в κачесτве οснοвы πρименена жидκοοбρазная масса πлаценτаρнοю маτеρиала. κοτορая имееτ гοмοгенную сτρуκτуρу. и на- χοдиτся в смеτанοοбρазнοм сοсτοянии. а ее маτеρиал - в16. Medicinal product. Consisting of and. Гη- 15 finely ground placenta material and mixed with her target supplement. different. that, on the basis of quality, the liquid mass of the placental material is used. It has a homogeneous structure. and is in a mixed state. and her material - in
20 наττивнοм сοсτοянии и οбρабοτан 6- 10 % уκсуснοй κи- слοτοй в κοличесτве дο 10 % οτ οбщей массы. πρи эτοм в κачесτве целевοй дοбавκи πρименена 6- 10 % уκсусная κислοτа в κοличесτве ρавнοм или πρевышаюшем κοли- чесτвο маτеρиала οснοвы.20% of the livestock and processed 6-10% acetic acid in the amount of up to 10% of the total weight. Therefore, in the quality of the target supplement, 6–10% acetic acid is used in the amount of equal or higher amount of the base material.
25 17. Леκаρсτвеннοе сρедсτвο. сοдеρжашее οснοву из из- мельченнοгο πлаценτаρнοгο маτеρиала и смешанную с ней целевую дοбавκу. οτличающееся τем. чτο οснοва сο смешеннοй с ней целевοй дοбавκοй наχοдяτся вο всπе- неннοй массе. в κοτοροй в κачесτве οснοвы πρименена зο жидκοοбρазная масса πлаценτаρнοгο маτеρиала. имею- щая гοмοгенную сτρуκτуρу, а ее маτеρиал. οбρабοτан- ный димеτилсульφοκсидοм в κοличесτве дο 10 % οτ οб- щей массы. - наττивнοе сοсτοяние, πρи эτοм в κачесτве целевοй дοбавκи πρименена сτеаρинοвая κислοτа или25 17. Medicinal product. a commercially available base of crushed placental material and a targeted supplement mixed with it. different. that the main target mixed with it is the target added amount in the whole mass. In a short-term basis, the liquid bulk of the placenta is used. having a homogeneous structure, and its material. The processed dimethyl sulfide in quantities of up to 10% of the total mass. - a satisfactory condition, and thus, in the quality of the target supplement, a stable acid is used or
35 мылο в κοличесτве и сοοτнοшенияχ. οбρазуюшиχ всπе- ненную массу. 35 soaps in quantity and proportions. universally known universal mass.
18. Леκаρсτвеннοе сρедсτвο, сοдеρжащее οснοву из πла- ценτаρнοгο маτеρиала и целевую дοбавκу, οτличаюшее- \νθ 97/48405 ΡСΤ/ΚШ6/0016818. The medicinal product, which contains the basis of the base material and the target supplement, which differs from \ νθ 97/48405 ΡСΤ / ΚШ6 / 00168
4545
ся τем. чτο в κачесτве οснοвы πρименена амниοτичесκая οбοποчκа, οτделенная οτ πлаценτаρнοгο маτеρиала. на- χοдящегοся в наττивнοм сοсτοянии, а в κачесτве целевοй дοбавκи πρименен димеτилсульφοκсид и/или анτибиο- 5 τиκ в κοличесτве и сοοτнοшенияχ. синеρгеτичесκи уси- ливаюшиχ τеρаπевτичесκий эφφеκτ маτеρиала οснοвы. πρи эτοм амниοτичесκая οбοлοчκа οδρабοτана 0.5 мο- ляρным ρасτвοροм χлορида наτρия и имеем наττивную сτρуκτуρу.this. that, on the basis of the base, the amnesty sample, separated from the placenta material, is used. in the actual state, and in the quality of the target supplement, dimethyl sulfide and / or antibiotic 5 are used in quantity and condition. synergistically enhancing therapeutic effect of the base material. In this case, the amnestic treatment was processed by a 0.5 molar solution of sodium chloride and we have a net structure.
19. Леκаρсτвеннοе сρедсτвο πο π.1 8. οτличающееся τем. чτο амниοτичесκая οбοлοчκа προπиτана глицеρинοм и замοροжена.19. Medicinal product π.1 8. different. the amnestic is impregnated with glycerin and is frozen.
20. Леκаρсτвеннοе сρедсτвο . сοдеρжащее οснοву из из- мельченнοгο πлаценτаρнοгο маτеρиала и смешанную с20. Medicinal product. consisting of a crushed placental material and mixed with
15 ней целевую дοбавκу. οτличающееся τем. чτο οснοва сο смешаннοй с ней целевοй дοбавκοй наχοдяτс в жидκοм сοсτοянии сο сτρуκτуροй τалοй жидκοсτи. выделеннοй из жидκοοбρазнοгο πлаценτаρнοгο маτеρиала. οбρабο- τаннοгο целевοй дοбавκοй. в κачесτве κοτοροй πρименен15 her target supplement. different. that the basic mix with it is a special purpose supplement found in a liquid state of a structured solid liquid. isolated from a liquid placental material. Convenient target add-on. in the quality of imen
20 димеτилсульφοκсид. взяτый в κοличесτве бοлее 1 0 % οτ массы уποмянуτοгο маτеρиала.20 dimethyl sulfide. taken in quantities of more than 1 0% of the total weight of the reclaimed material.
21.21.
9"> 9 ">
PCT/RU1996/000168 1996-06-21 1996-06-21 Semi-finished product for producing drug bases, bases obtained using the same and variants, and drugs obtained using these bases and variants WO1997048405A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/RU1996/000168 WO1997048405A1 (en) 1996-06-21 1996-06-21 Semi-finished product for producing drug bases, bases obtained using the same and variants, and drugs obtained using these bases and variants
AU70030/96A AU7003096A (en) 1996-06-21 1996-06-21 Semi-finished product for producing drug bases, bases obtained using the same and variants, and drugs obtained using these bases and variants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU1996/000168 WO1997048405A1 (en) 1996-06-21 1996-06-21 Semi-finished product for producing drug bases, bases obtained using the same and variants, and drugs obtained using these bases and variants

Publications (1)

Publication Number Publication Date
WO1997048405A1 true WO1997048405A1 (en) 1997-12-24

Family

ID=20130008

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU1996/000168 WO1997048405A1 (en) 1996-06-21 1996-06-21 Semi-finished product for producing drug bases, bases obtained using the same and variants, and drugs obtained using these bases and variants

Country Status (2)

Country Link
AU (1) AU7003096A (en)
WO (1) WO1997048405A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000050047A3 (en) * 1999-02-22 2000-12-21 Ct De Histoterapia Placentaria Composition for the treatment of psoriasis
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
US8105634B2 (en) 2006-08-15 2012-01-31 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US8399514B2 (en) 2007-02-08 2013-03-19 Biogen Idec Ma Inc. Treatment for multiple sclerosis
US8821857B2 (en) 2006-10-06 2014-09-02 Anthrogenesis Corporation Human placental collagen compositions and methods of making and using the same
US8980832B2 (en) 2003-09-09 2015-03-17 Biogen Idec International Gmbh Use of fumaric acid derivatives for treating cardiac insufficiency, and asthma

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1061818A1 (en) * 1982-07-19 1983-12-23 Центральный научно-исследовательский кожно-венерологический институт Method of treatment of pustular psoriasis
SU1169578A1 (en) * 1984-01-09 1985-07-30 Bezrukov Oleg F Method of preservation of amniotic casing
EP0246824A2 (en) * 1986-05-15 1987-11-25 Cell Systems Ltd Biological cryoprotection
GB2219923A (en) * 1988-06-22 1989-12-28 Inst Kriobiologii I Kriomedits Method for low-temperature preservation of embryos

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1061818A1 (en) * 1982-07-19 1983-12-23 Центральный научно-исследовательский кожно-венерологический институт Method of treatment of pustular psoriasis
SU1169578A1 (en) * 1984-01-09 1985-07-30 Bezrukov Oleg F Method of preservation of amniotic casing
EP0246824A2 (en) * 1986-05-15 1987-11-25 Cell Systems Ltd Biological cryoprotection
GB2219923A (en) * 1988-06-22 1989-12-28 Inst Kriobiologii I Kriomedits Method for low-temperature preservation of embryos

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000050047A3 (en) * 1999-02-22 2000-12-21 Ct De Histoterapia Placentaria Composition for the treatment of psoriasis
US8980832B2 (en) 2003-09-09 2015-03-17 Biogen Idec International Gmbh Use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
US8105634B2 (en) 2006-08-15 2012-01-31 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
US8821857B2 (en) 2006-10-06 2014-09-02 Anthrogenesis Corporation Human placental collagen compositions and methods of making and using the same
US8877180B2 (en) 2006-10-06 2014-11-04 Anthrogenesis Corporation Human placental collagen compositions, and methods of making and using the same
US9770488B2 (en) 2006-10-06 2017-09-26 Anthrogenesis Corporation Human placental collagen compositions, and methods of making and using the same
US9775886B2 (en) 2006-10-06 2017-10-03 Celularity, Inc. Human placental collagen compositions, and methods of making and using the same
US9974840B2 (en) 2006-10-06 2018-05-22 Celularity, Inc. Human placental collagen compositions, and methods of making and using the same
US8399514B2 (en) 2007-02-08 2013-03-19 Biogen Idec Ma Inc. Treatment for multiple sclerosis

Also Published As

Publication number Publication date
AU7003096A (en) 1998-01-07

Similar Documents

Publication Publication Date Title
Mujoriya et al. A study on wheat grass and its nutritional value
WO1990012584A1 (en) Preparation with an anti-inflammatory, lactogenous and stimulating action, and method of obtaining it
US10758578B2 (en) Herbal formulations of carnivorous plants and methods for treating inflammation
WO1994001099A1 (en) Pharmaceutical composition having anti-alcohol, radioprotecting and anti-choleraic activity and stimulating energy metabolism, stomach mucous membrane acid-generation and secretion functions
WO1997048405A1 (en) Semi-finished product for producing drug bases, bases obtained using the same and variants, and drugs obtained using these bases and variants
WO1995017902A1 (en) Use of a strain of the fungus fusarium as a substance producer and a preparation based on it with adaptogenic and immunomodulating properties
Osipchuk et al. The Use of Biologically Active Substances from Plant Raw Materials in Certain Physiological Conditions of Cows
DE60010886T2 (en) EXTRACTS, FORMULATION AND USE OF MEDICAMENTS FROM LEAVES OF CAJANUS CAJAN (L.) MILSP.
CN103932941A (en) Nutritional element aging resistant skin-care lotion
CN107596355A (en) A kind of Medical pain easing, the exterior-applied gel subsided a swelling, brought down a fever and preparation method thereof
Morse The Detox Miracle Sourcebook: Raw Foods and Herbs for Complete Cellular Regeneration
CN1240408C (en) Ointment for treating chilblain
WO1991000098A1 (en) Anti-inflammatory preparation and method of obtaining it
WO1995011659A2 (en) Pharmaceutical preparation with immuno-correcting properties based on a cell suspension, and a method of treating sugar diabetes using said preparation
CN1189301A (en) Active pollen paste and its processing method
RU2156131C1 (en) Semifinished product for preparing drug base, drug base made of this semifinished product (variants) and drug based on this base (variants)
WO1995034309A1 (en) Base for a medicament and a medicament based thereon (variants)
Roberts Tissue Salts for Healthy Living
Flora The Wellness Dictionary
Anthis The Complete Book of Essential Oils for Mama and Baby: Safe and Natural Remedies for Pregnancy, Birth, and Children
Totawar Critical review of the utilization of Panchagavya in the form of Nutraceuticals
Zago Cancer Can Be Cured!
EP2826483A2 (en) Mixture of substances comprising ribose and amino acids for treating sepsis, coagulopathies, bone healing disorders and/or bone bleeding
Kidd Dr. Kidd's Guide to Herbal Cat Care
CN1712009A (en) Externally-applied medicinal liquid for treating acne, rosacea and folliculitis

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AU BR BY CA CN GB JP KR KZ MD RU UA US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: JP

Ref document number: 98502751

Format of ref document f/p: F

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA