WO1998008550A1 - Fragmented polymeric hydrogels for adhesion prevention and their preparation - Google Patents
Fragmented polymeric hydrogels for adhesion prevention and their preparation Download PDFInfo
- Publication number
- WO1998008550A1 WO1998008550A1 PCT/US1997/015262 US9715262W WO9808550A1 WO 1998008550 A1 WO1998008550 A1 WO 1998008550A1 US 9715262 W US9715262 W US 9715262W WO 9808550 A1 WO9808550 A1 WO 9808550A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cross
- composition
- tissue
- linked
- hydrogel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0015—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0031—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/145—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Materials Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002264647A CA2264647C (en) | 1996-08-27 | 1997-08-14 | Fragmented polymeric hydrogels for adhesion prevention and their preparation |
BRPI9711241A BR9711241B8 (en) | 1996-08-27 | 1997-08-14 | process for making a polymeric composition to prevent or inhibit the formation of tissue adhesions or to inhibit bleeding |
EP97940692A EP0927053B1 (en) | 1996-08-27 | 1997-08-14 | Fragmented polymeric hydrogels for adhesion prevention and their preparation |
IL12849697A IL128496A (en) | 1996-08-27 | 1997-08-14 | Fragemented polymeric hydrogel composition for adhesion prevention and a method for making the same |
DE69720479T DE69720479T2 (en) | 1996-08-27 | 1997-08-14 | FRAGMENTED POLYMERS HYDROGELS TO PREVENT TISSUE BONDING AND THEIR PRODUCTION |
JP51197098A JP4418535B2 (en) | 1996-08-27 | 1997-08-14 | Fragmented polymer hydrogels for the prevention of adhesion and their preparation |
AU42412/97A AU719534B2 (en) | 1996-08-27 | 1997-08-14 | Fragmented polymeric hydrogels for adhesion prevention and their preparation |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70485296A | 1996-08-27 | 1996-08-27 | |
US08/704,852 | 1996-08-27 | ||
US08/903,674 US6063061A (en) | 1996-08-27 | 1997-07-31 | Fragmented polymeric compositions and methods for their use |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998008550A1 true WO1998008550A1 (en) | 1998-03-05 |
Family
ID=27107390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/015262 WO1998008550A1 (en) | 1996-08-27 | 1997-08-14 | Fragmented polymeric hydrogels for adhesion prevention and their preparation |
Country Status (10)
Country | Link |
---|---|
US (1) | US6063061A (en) |
EP (1) | EP0927053B1 (en) |
JP (3) | JP4418535B2 (en) |
AU (1) | AU719534B2 (en) |
BR (1) | BR9711241B8 (en) |
CA (1) | CA2264647C (en) |
DE (1) | DE69720479T2 (en) |
IL (1) | IL128496A (en) |
RU (1) | RU2207882C2 (en) |
WO (1) | WO1998008550A1 (en) |
Cited By (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000032225A1 (en) * | 1998-12-03 | 2000-06-08 | University College London | Tissue repair |
WO2000076533A1 (en) | 1999-06-10 | 2000-12-21 | Fusion Medical Technologies, Inc. | Hemoactive compositions and methods for their manufacture and use |
EP1109498A1 (en) * | 1998-08-04 | 2001-06-27 | Fusion Medical Technologies, Inc. | Percutaneous tissue track closure assembly and method |
WO2002074356A1 (en) * | 2001-03-16 | 2002-09-26 | Vivoxid Oy | Composite for attaching, growing and/or repairing of living tissues and use of said composite |
EP1274369A2 (en) * | 1999-09-13 | 2003-01-15 | Keraplast Technologies Ltd. | Implantable prosthetic or tissue expanding device |
US6914126B2 (en) | 2002-04-10 | 2005-07-05 | Keraplast Technologies, Ltd. | Methods for producing, films comprising, and methods for using heterogenous crosslinked protein networks |
US6989437B2 (en) | 2002-04-10 | 2006-01-24 | Keraplast Technologies, Ltd. | Methods for producing, films comprising, and methods for using heterogeneous crosslinked protein networks |
US7001988B2 (en) | 2001-09-25 | 2006-02-21 | Keraplast Technologies, Ltd. | Methods for controlling peptide solubility, chemically modified peptides, and stable solvent systems for producing same |
US7001987B2 (en) | 2002-04-22 | 2006-02-21 | Keraplast Technologies, Ltd. | Hydrogel with controllable mechanical, chemical, and biological properties and method for making same |
US7109163B2 (en) | 2004-01-30 | 2006-09-19 | Ethicon, Inc. | Hemostatic compositions and devices |
WO2006113249A2 (en) * | 2005-04-12 | 2006-10-26 | Warsaw Orthopedic, Inc. | Methods and devices for preserving motion in an articulating prosthetic disc |
US7320962B2 (en) | 1996-08-27 | 2008-01-22 | Baxter International Inc. | Hemoactive compositions and methods for their manufacture and use |
FR2909285A1 (en) * | 2006-12-01 | 2008-06-06 | Anteis Sa | Use of an injectable or implantable antiadhesive antifibrotic gel based on a crosslinked natural or synthetic polymer for treating glaucoma or surgical wounds |
US7501485B2 (en) | 2002-01-28 | 2009-03-10 | Keraplast Technologies, Ltd. | Bioactive keratin peptides |
US7718412B2 (en) | 2003-08-07 | 2010-05-18 | Ethicon, Inc. | Hemostatic compositions containing sterile thrombin |
WO2010027471A3 (en) * | 2008-09-04 | 2010-07-08 | The General Hospital Corporation | Hydrogels for vocal cord and soft tissue augmentation and repair |
US7833965B2 (en) | 2003-08-07 | 2010-11-16 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
US7871637B2 (en) | 1996-08-27 | 2011-01-18 | Baxter International Inc. | Dry hemostatic compositions and methods for their preparation |
WO2011151384A1 (en) | 2010-06-01 | 2011-12-08 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
WO2011151386A1 (en) | 2010-06-01 | 2011-12-08 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
WO2011151400A1 (en) | 2010-06-01 | 2011-12-08 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
US8092820B2 (en) | 2001-07-17 | 2012-01-10 | Baxter International Inc. | Dry hemostatic compositions and methods for their preparation |
US8119160B2 (en) | 2004-06-29 | 2012-02-21 | Ethicon, Inc. | Hemostatic compositions and devices |
US8258093B2 (en) | 2006-02-17 | 2012-09-04 | Wake Forest University Health Sciences | Wound healing compositions containing keratin biomaterials |
US8299013B2 (en) | 2006-02-17 | 2012-10-30 | Wake Forest University Health Sciences | Clotting and healing compositions containing keratin biomaterials |
US8303981B2 (en) | 1996-08-27 | 2012-11-06 | Baxter International Inc. | Fragmented polymeric compositions and methods for their use |
US8357378B2 (en) | 1996-08-27 | 2013-01-22 | Baxter International Inc. | Fragmented polymeric compositions and methods for their use |
WO2013053755A2 (en) | 2011-10-11 | 2013-04-18 | Baxter International Inc. | Hemostatic compositions |
WO2013053749A2 (en) | 2011-10-11 | 2013-04-18 | Baxter International Inc. | Hemostatic compositions |
WO2013053759A2 (en) | 2011-10-11 | 2013-04-18 | Baxter International Inc. | Hemostatic compositions |
WO2013053753A2 (en) | 2011-10-11 | 2013-04-18 | Baxter International Inc. | Hemostatic composition |
WO2013060769A2 (en) | 2011-10-27 | 2013-05-02 | Baxter International Inc. | Hemostatic compositions |
WO2013060770A1 (en) | 2011-10-27 | 2013-05-02 | Baxter International Inc. | Hemostatic compositions |
US8440225B2 (en) | 2003-08-07 | 2013-05-14 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
CN103209716A (en) * | 2010-09-21 | 2013-07-17 | 学校法人同志社 | Suture reinforcing material being for use in automatic suturing devices and containing hydrophilic polymer |
US8545893B2 (en) | 2010-03-08 | 2013-10-01 | Wake Forest University Health Sciences | Keratin biomaterials for treatment of ischemia |
US8603511B2 (en) | 1996-08-27 | 2013-12-10 | Baxter International, Inc. | Fragmented polymeric compositions and methods for their use |
US8637231B2 (en) | 2004-08-17 | 2014-01-28 | Wake Forest University Health Sciences | Method for increasing the volume of a blood substitute with an expander comprising basic alpha keratose |
CN103732265A (en) * | 2011-08-02 | 2014-04-16 | 大日精化工业株式会社 | Anti-adhesion medical material and method for producing same |
US8703170B2 (en) | 2010-04-07 | 2014-04-22 | Baxter International Inc. | Hemostatic sponge |
US8703122B2 (en) | 2006-05-31 | 2014-04-22 | Baxter International Inc. | Method for directed cell in-growth and controlled tissue regeneration in spinal surgery |
US8771258B2 (en) | 2009-12-16 | 2014-07-08 | Baxter International Inc. | Hemostatic sponge |
US8790698B2 (en) | 2007-10-30 | 2014-07-29 | Baxter International Inc. | Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects |
US8834864B2 (en) | 2003-06-05 | 2014-09-16 | Baxter International Inc. | Methods for repairing and regenerating human dura mater |
US8846075B2 (en) | 2003-01-24 | 2014-09-30 | Magle Holding Ab | Composition material for transmucosal delivery |
US8920827B2 (en) | 2005-10-21 | 2014-12-30 | Wake Forest University Health Sciences | Keratin bioceramic compositions |
US8962025B2 (en) | 2006-08-02 | 2015-02-24 | Baxter International Inc. | Rapidly acting dry sealant and methods for use and manufacture |
US8968764B2 (en) | 2006-02-10 | 2015-03-03 | Wake Forest University Health Sciences | Nerve regeneration employing keratin biomaterials |
US9039783B2 (en) | 2009-05-18 | 2015-05-26 | Baxter International, Inc. | Method for the improvement of mesh implant biocompatibility |
US9068162B2 (en) | 2007-08-17 | 2015-06-30 | Wake Forest University Health Sciences | Keratin biomaterials for cell culture and methods of use |
CN104861179A (en) * | 2015-06-03 | 2015-08-26 | 西北师范大学 | Preparation for feather keratin and sodium alginate composite polymer double-sensitive hydrogel and application therefore as drug carrier |
CN104892864A (en) * | 2015-06-03 | 2015-09-09 | 西北师范大学 | Preparation of keratin-sodium alginate composite microporous gel and application of gel as drug carrier |
US9162006B2 (en) | 2009-06-16 | 2015-10-20 | Baxter International Inc. | Hemostatic sponge |
US9198568B2 (en) | 2010-03-04 | 2015-12-01 | The General Hospital Corporation | Methods and systems of matching voice deficits with a tunable mucosal implant to restore and enhance individualized human sound and voice production |
US9220754B2 (en) | 2010-11-17 | 2015-12-29 | Wake Forest University Health Sciences | Keratin compositions for treatment of bone deficiency or injury |
US9265858B2 (en) | 2012-06-12 | 2016-02-23 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
US9533069B2 (en) | 2008-02-29 | 2017-01-03 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
US9724078B2 (en) | 2013-06-21 | 2017-08-08 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
EP2726115B1 (en) | 2011-06-30 | 2017-09-13 | Ethicon, Inc | Procoagulant peptides and their derivatives and uses therefor |
CN108314790A (en) * | 2018-03-16 | 2018-07-24 | 东华大学 | A kind of photo-crosslinking thio chitosan-polyethylene glycol methacrylate-styrene polymer hydrogel and preparation method thereof for tissue adhesive |
CN108498871A (en) * | 2018-03-23 | 2018-09-07 | 中南大学湘雅二医院 | A kind of preparation of autologous organisms protein hydrogel and its application in ophthalmology |
US10098961B2 (en) | 2011-02-03 | 2018-10-16 | Q-Med Ab | Hyaluronic acid composition |
US10111980B2 (en) | 2013-12-11 | 2018-10-30 | Ferrosan Medical Devices A/S | Dry composition comprising an extrusion enhancer |
CN108853598A (en) * | 2018-03-23 | 2018-11-23 | 中南大学湘雅二医院 | A kind of preparation of autologous organisms protein hydrogel and its application in operation on retina |
US10434213B2 (en) | 2010-03-05 | 2019-10-08 | Wake Forest University Health Sciences | Controlled delivery system |
US10653837B2 (en) | 2014-12-24 | 2020-05-19 | Ferrosan Medical Devices A/S | Syringe for retaining and mixing first and second substances |
US10660945B2 (en) | 2015-08-07 | 2020-05-26 | Victor Matthew Phillips | Flowable hemostatic gel composition and its methods of use |
US10751444B2 (en) | 2015-08-07 | 2020-08-25 | Victor Matthew Phillips | Flowable hemostatic gel composition and its methods of use |
US10918796B2 (en) | 2015-07-03 | 2021-02-16 | Ferrosan Medical Devices A/S | Syringe for mixing two components and for retaining a vacuum in a storage condition |
US11046818B2 (en) | 2014-10-13 | 2021-06-29 | Ferrosan Medical Devices A/S | Dry composition for use in haemostasis and wound healing |
US11109849B2 (en) | 2012-03-06 | 2021-09-07 | Ferrosan Medical Devices A/S | Pressurized container containing haemostatic paste |
EP3943127A1 (en) | 2015-09-01 | 2022-01-26 | Baxter International Inc | Hemostatic material |
US11458226B2 (en) | 2004-04-08 | 2022-10-04 | Galderma Holding SA | Method of soft tissue augmentation |
US11801324B2 (en) | 2018-05-09 | 2023-10-31 | Ferrosan Medical Devices A/S | Method for preparing a haemostatic composition |
Families Citing this family (161)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6183497B1 (en) * | 1998-05-01 | 2001-02-06 | Sub-Q, Inc. | Absorbable sponge with contrasting agent |
US6071300A (en) * | 1995-09-15 | 2000-06-06 | Sub-Q Inc. | Apparatus and method for percutaneous sealing of blood vessel punctures |
US6063061A (en) * | 1996-08-27 | 2000-05-16 | Fusion Medical Technologies, Inc. | Fragmented polymeric compositions and methods for their use |
AT407117B (en) * | 1997-09-19 | 2000-12-27 | Immuno Ag | FIBRINE SPONGE |
US6315753B1 (en) * | 1998-05-01 | 2001-11-13 | Sub-Q, Inc. | System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge |
US20010045575A1 (en) * | 1998-05-01 | 2001-11-29 | Mark Ashby | Device and method for facilitating hemostasis of a biopsy tract |
US6605294B2 (en) * | 1998-08-14 | 2003-08-12 | Incept Llc | Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels |
US7347850B2 (en) * | 1998-08-14 | 2008-03-25 | Incept Llc | Adhesion barriers applicable by minimally invasive surgery and methods of use thereof |
US7790192B2 (en) | 1998-08-14 | 2010-09-07 | Accessclosure, Inc. | Apparatus and methods for sealing a vascular puncture |
US6152943A (en) * | 1998-08-14 | 2000-11-28 | Incept Llc | Methods and apparatus for intraluminal deposition of hydrogels |
US20080114092A1 (en) * | 1998-12-04 | 2008-05-15 | Incept Llc | Adhesion barriers applicable by minimally invasive surgery and methods of use thereof |
US6679870B1 (en) * | 1999-07-23 | 2004-01-20 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
US6685694B2 (en) * | 1999-07-23 | 2004-02-03 | Vasca, Inc. | Methods and kits for locking and disinfecting implanted catheters |
US6783546B2 (en) | 1999-09-13 | 2004-08-31 | Keraplast Technologies, Ltd. | Implantable prosthetic or tissue expanding device |
US6984219B2 (en) * | 1999-09-23 | 2006-01-10 | Mark Ashby | Depth and puncture control for blood vessel hemostasis system |
AU778318B2 (en) * | 2000-02-03 | 2004-11-25 | Tissuemed Limited | Device for the closure of a surgical puncture |
GB0011169D0 (en) * | 2000-05-10 | 2000-06-28 | Reckitt & Colmann Prod Ltd | Improvements in or relating to medicinal compositions |
DE60108258T2 (en) * | 2000-10-23 | 2006-03-16 | Tissuemed Ltd. | SELF-ADHESIVE, HYDRATABLE MATRIX FOR THERAPEUTIC APPLICATIONS |
US9080146B2 (en) | 2001-01-11 | 2015-07-14 | Celonova Biosciences, Inc. | Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface |
US8187625B2 (en) | 2001-03-12 | 2012-05-29 | Boston Scientific Scimed, Inc. | Cross-linked gelatin composition comprising a wetting agent |
EP1392182A1 (en) * | 2001-05-04 | 2004-03-03 | Concentric Medical | Hydrogel vaso-occlusive device |
US7008440B2 (en) * | 2001-11-08 | 2006-03-07 | Sub-Q, Inc. | System and method for delivering hemostasis promoting material to a blood vessel puncture site by fluid pressure |
US6592608B2 (en) * | 2001-12-07 | 2003-07-15 | Biopsy Sciences, Llc | Bioabsorbable sealant |
US7923431B2 (en) | 2001-12-21 | 2011-04-12 | Ferrosan Medical Devices A/S | Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis |
US20080226723A1 (en) * | 2002-07-05 | 2008-09-18 | Celonova Biosciences, Inc. | Loadable Polymeric Particles for Therapeutic Use in Erectile Dysfunction and Methods of Preparing and Using the Same |
US7135027B2 (en) | 2002-10-04 | 2006-11-14 | Baxter International, Inc. | Devices and methods for mixing and extruding medically useful compositions |
PL377477A1 (en) * | 2002-12-11 | 2006-02-06 | Ferrosan A/S | Gelatine-based materials as swabs |
CA2514325C (en) * | 2003-01-24 | 2013-11-12 | Magle Holding Ab | A composition material for transmucosal delivery |
KR20060003872A (en) * | 2003-04-04 | 2006-01-11 | 티슈메드 리미티드 | Tissue-adhesive formulations |
US9289195B2 (en) | 2003-06-04 | 2016-03-22 | Access Closure, Inc. | Auto-retraction apparatus and methods for sealing a vascular puncture |
US7331979B2 (en) * | 2003-06-04 | 2008-02-19 | Access Closure, Inc. | Apparatus and methods for sealing a vascular puncture |
US20070020314A1 (en) * | 2003-06-30 | 2007-01-25 | Hirotaka Haro | Adhesion inhibiting material for vertebral/spinal operation |
US20050033157A1 (en) * | 2003-07-25 | 2005-02-10 | Klein Dean A. | Multi-modality marking material and method |
US20050036955A1 (en) * | 2003-08-13 | 2005-02-17 | Degould Michael D. | Bioresorbable tooth extraction socket dressing |
US20050148512A1 (en) * | 2003-11-10 | 2005-07-07 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
US20050208095A1 (en) * | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Polymer compositions and methods for their use |
US7875043B1 (en) | 2003-12-09 | 2011-01-25 | Sub-Q, Inc. | Cinching loop |
WO2005072700A2 (en) * | 2004-01-30 | 2005-08-11 | Ferrosan A/S | Haemostatic sprays and compositions |
ATE553186T1 (en) * | 2004-02-20 | 2012-04-15 | Isto Technologies Inc | DISC REPAIR AND METHOD THEREOF |
US20060275273A1 (en) * | 2004-02-20 | 2006-12-07 | Seyedin Mitchell S | Intervertebral Disc Repair, Methods and Devices Therefor |
US20050187429A1 (en) * | 2004-02-23 | 2005-08-25 | Poppas Dix P. | Vaginal rejuvenation |
AU2005262070B2 (en) * | 2004-07-09 | 2011-01-27 | Ferrosan Medical Devices A/S | Haemostatic composition comprising hyaluronic acid |
KR20070051297A (en) * | 2004-08-03 | 2007-05-17 | 티슈메드 리미티드 | Tissue-adhesive materials |
US8348971B2 (en) | 2004-08-27 | 2013-01-08 | Accessclosure, Inc. | Apparatus and methods for facilitating hemostasis within a vascular puncture |
DE102004047115B9 (en) | 2004-09-27 | 2007-10-31 | Universität Hamburg | Method for producing a wound dressing |
US7235592B2 (en) | 2004-10-12 | 2007-06-26 | Zimmer Gmbh | PVA hydrogel |
US9107850B2 (en) * | 2004-10-25 | 2015-08-18 | Celonova Biosciences, Inc. | Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same |
US9114162B2 (en) | 2004-10-25 | 2015-08-25 | Celonova Biosciences, Inc. | Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same |
AU2005298344B2 (en) | 2004-10-25 | 2011-02-10 | Varian Medical Systems, Inc. | Loadable polyphosphazene-comprising particles for therapeutic and/or diagnostic applications and methods of preparing and using the same |
US20210299056A9 (en) | 2004-10-25 | 2021-09-30 | Varian Medical Systems, Inc. | Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods |
US8262693B2 (en) * | 2004-11-05 | 2012-09-11 | Accessclosure, Inc. | Apparatus and methods for sealing a vascular puncture |
US8663225B2 (en) | 2004-11-12 | 2014-03-04 | Medtronic, Inc. | Hydrogel bone void filler |
US7530578B2 (en) * | 2004-11-17 | 2009-05-12 | Continental Commercial Products, Llc | Step-on receptacle with tip prevention |
JP2008531769A (en) | 2005-02-23 | 2008-08-14 | ズィマー・テクノロジー・インコーポレーテッド | Blend hydrogel and method for producing the same |
US7857856B2 (en) * | 2005-03-15 | 2010-12-28 | Warsaw Ortho Pedic, Inc. | Composite spinal nucleus implant with water absorption and swelling capabilities |
US20060222596A1 (en) | 2005-04-01 | 2006-10-05 | Trivascular, Inc. | Non-degradable, low swelling, water soluble radiopaque hydrogel polymer |
US9119901B2 (en) | 2005-04-28 | 2015-09-01 | Warsaw Orthopedic, Inc. | Surface treatments for promoting selective tissue attachment to medical impants |
US8414907B2 (en) | 2005-04-28 | 2013-04-09 | Warsaw Orthopedic, Inc. | Coatings on medical implants to guide soft tissue healing |
EP3725299A1 (en) | 2005-06-24 | 2020-10-21 | Duke University | A direct drug delivery system based on thermally responsive biopolymers |
SI1940439T1 (en) | 2005-08-11 | 2011-02-28 | Univ Saskatchewan | Reducing post-operative adhesion formation with intraperitoneal glutamine |
US20070074980A1 (en) * | 2005-09-02 | 2007-04-05 | Bankoski Brian R | Implant rehydration packages and methods of use |
CN101296726B (en) * | 2005-10-28 | 2012-05-30 | 巴克斯特国际公司 | Applicator and method of using same |
US9101742B2 (en) * | 2005-10-28 | 2015-08-11 | Baxter International Inc. | Gastrointestinal applicator and method of using same |
US20070110788A1 (en) * | 2005-11-14 | 2007-05-17 | Hissong James B | Injectable formulation capable of forming a drug-releasing device |
CA2632120C (en) | 2005-12-07 | 2014-07-08 | Zimmer, Inc. | Methods of bonding or modifying hydrogels using irradiation |
US20130172274A1 (en) | 2005-12-20 | 2013-07-04 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
US8841255B2 (en) | 2005-12-20 | 2014-09-23 | Duke University | Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides |
WO2007073486A2 (en) | 2005-12-20 | 2007-06-28 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
US8017107B2 (en) | 2005-12-22 | 2011-09-13 | Zimmer, Inc. | Perfluorocyclobutane crosslinked hydrogels |
JP2007177074A (en) * | 2005-12-28 | 2007-07-12 | Tohoku Univ | Composition and its manufacturing method |
CA2640629A1 (en) | 2006-02-03 | 2007-08-09 | Tissuemed Limited | Tissue-adhesive materials |
US20090018575A1 (en) * | 2006-03-01 | 2009-01-15 | Tissuemed Limited | Tissue-adhesive formulations |
US8110242B2 (en) | 2006-03-24 | 2012-02-07 | Zimmer, Inc. | Methods of preparing hydrogel coatings |
US8795709B2 (en) * | 2006-03-29 | 2014-08-05 | Incept Llc | Superabsorbent, freeze dried hydrogels for medical applications |
CA2650473C (en) * | 2006-04-24 | 2013-06-18 | Incept, Llc | Protein crosslinkers, crosslinking methods and applications thereof |
US7976873B2 (en) * | 2006-05-10 | 2011-07-12 | Medtronic Xomed, Inc. | Extracellular polysaccharide solvating system for treatment of bacterial ear conditions |
US20070264296A1 (en) * | 2006-05-10 | 2007-11-15 | Myntti Matthew F | Biofilm extracellular polysachharide solvating system |
US7993675B2 (en) * | 2006-05-10 | 2011-08-09 | Medtronic Xomed, Inc. | Solvating system and sealant for medical use in the sinuses and nasal passages |
US7959943B2 (en) * | 2006-05-10 | 2011-06-14 | Medtronics Xomed, Inc. | Solvating system and sealant for medical use in the middle or inner ear |
US7872068B2 (en) | 2006-05-30 | 2011-01-18 | Incept Llc | Materials formable in situ within a medical device |
US8167847B2 (en) | 2006-06-22 | 2012-05-01 | Excelsior Medical Corporation | Antiseptic cap and antiseptic cap equipped plunger and syringe barrel assembly |
US7671014B2 (en) | 2006-08-14 | 2010-03-02 | Warsaw Orthopedic, Inc. | Flowable carrier matrix and methods for delivering to a patient |
US20090012413A1 (en) * | 2006-09-08 | 2009-01-08 | Sabbah Hani N | Cardiac patterning for improving diastolic function |
CA2662169C (en) * | 2006-09-08 | 2018-03-20 | Symphony Medical, Inc. | Intramyocardial patterning for global cardiac resizing and reshaping |
WO2008033964A2 (en) | 2006-09-13 | 2008-03-20 | Accessclosure, Inc. | Apparatus for sealing a vascular puncture |
WO2008076407A2 (en) | 2006-12-15 | 2008-06-26 | Lifebond Ltd. | Gelatin-transglutaminase hemostatic dressings and sealants |
US8088095B2 (en) | 2007-02-08 | 2012-01-03 | Medtronic Xomed, Inc. | Polymeric sealant for medical use |
CA2578647A1 (en) * | 2007-02-15 | 2008-08-15 | University Of Saskatchewan | Reducing post-operative adhesion formation with intraperitoneal glutamine |
US8932560B2 (en) | 2007-09-04 | 2015-01-13 | University of Maryland, College Parke | Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells |
CA2682160C (en) * | 2007-04-11 | 2017-04-04 | Henry Ford Health System | Cardiac repair, resizing and reshaping using the venous system of the heart |
US7731988B2 (en) | 2007-08-03 | 2010-06-08 | Zimmer, Inc. | Multi-polymer hydrogels |
DE102007038125A1 (en) * | 2007-08-03 | 2009-02-05 | Aesculap Ag | Combination for bonding biological tissues |
GB0715514D0 (en) * | 2007-08-10 | 2007-09-19 | Tissuemed Ltd | Coated medical devices |
US8062739B2 (en) | 2007-08-31 | 2011-11-22 | Zimmer, Inc. | Hydrogels with gradient |
US7993367B2 (en) * | 2007-09-28 | 2011-08-09 | Accessclosure, Inc. | Apparatus and methods for sealing a vascular puncture |
US20090110738A1 (en) * | 2007-10-26 | 2009-04-30 | Celonova Biosciences, Inc. | Loadable Polymeric Particles for Cosmetic and Reconstructive Tissue Augmentation Applications and Methods of Preparing and Using the Same |
US20090111763A1 (en) * | 2007-10-26 | 2009-04-30 | Celonova Biosciences, Inc. | Loadable polymeric particles for bone augmentation and methods of preparing and using the same |
US20090110731A1 (en) * | 2007-10-30 | 2009-04-30 | Celonova Biosciences, Inc. | Loadable Polymeric Microparticles for Therapeutic Use in Alopecia and Methods of Preparing and Using the Same |
WO2009059217A2 (en) * | 2007-11-02 | 2009-05-07 | Incept, Llc | Apparatus and methods for sealing a vascular puncture |
US7947784B2 (en) | 2007-11-16 | 2011-05-24 | Zimmer, Inc. | Reactive compounding of hydrogels |
US8299316B2 (en) * | 2007-12-18 | 2012-10-30 | Ethicon, Inc. | Hemostatic device |
US8034362B2 (en) | 2008-01-04 | 2011-10-11 | Zimmer, Inc. | Chemical composition of hydrogels for use as articulating surfaces |
CN104888263B (en) * | 2008-01-14 | 2018-11-30 | 北京环球利康科技有限公司 | Biocompatible hemostatic prevents adhesion, promoting healing, the closed modified starch material of surgery |
US9629798B2 (en) * | 2008-04-03 | 2017-04-25 | Mallinckrodt Pharma Ip Trading D.A.C. | Hemostatic microspheres |
US8029533B2 (en) | 2008-04-04 | 2011-10-04 | Accessclosure, Inc. | Apparatus and methods for sealing a vascular puncture |
US9364206B2 (en) | 2008-04-04 | 2016-06-14 | Access Closure, Inc. | Apparatus and methods for sealing a vascular puncture |
US20090259210A1 (en) * | 2008-04-10 | 2009-10-15 | Sabbah Hani N | Method, apparatus and kits for forming structural members within the cardiac venous system |
US8801665B2 (en) * | 2008-04-10 | 2014-08-12 | Henry Ford Health System | Apparatus and method for controlled depth of injection into myocardial tissue |
CA2727432C (en) | 2008-06-12 | 2016-10-11 | Medtronic Xomed, Inc. | Method for treating chronic wounds with an extracellular polymeric substance solvating system |
WO2009153748A2 (en) * | 2008-06-18 | 2009-12-23 | Lifebond Ltd | Methods and devices for use with sealants |
WO2009153751A2 (en) * | 2008-06-18 | 2009-12-23 | Lifebond Ltd | A method for enzymatic cross-linking of a protein |
CN104031393B (en) | 2008-06-18 | 2017-08-01 | 生命连结有限公司 | Improved cross-linked composition |
CA2953975C (en) | 2008-06-27 | 2019-11-26 | Duke University | Therapeutic agents comprising elastin-like peptides |
EP2430982B1 (en) | 2008-08-26 | 2020-06-24 | St. Jude Medical, Inc. | System for sealing percutaneous punctures |
EP2346324A4 (en) | 2008-10-06 | 2012-10-10 | Microbial Defense Systems Llc | Antimicrobial composition and methods of making and using same |
EP2364112B1 (en) * | 2008-11-12 | 2016-03-09 | Accessclosure, Inc. | Apparatus and methods for sealing a vascular puncture |
CA2760704C (en) | 2009-05-04 | 2017-10-03 | Incept, Llc | Biomaterials for track and puncture closure |
JP2011025013A (en) * | 2009-06-25 | 2011-02-10 | Doshisha | Antiadhesive material and method for manufacturing the same |
KR101943420B1 (en) | 2009-08-14 | 2019-04-17 | 파세비오 파마수티컬스 인코포레이티드 | Modified Vasoactive Intestinal Peptide |
US9649331B2 (en) * | 2009-08-27 | 2017-05-16 | Ara Medical Llc | Sprayable polymers as adhesion barriers |
JP2013509963A (en) | 2009-11-09 | 2013-03-21 | スポットライト テクノロジー パートナーズ エルエルシー | Fragmented hydrogel |
CN102695500A (en) | 2009-11-09 | 2012-09-26 | 聚光灯技术合伙有限责任公司 | Polysaccharide based hydrogels |
CA2780898A1 (en) | 2009-11-13 | 2011-05-19 | University Of Maryland, College Park | Advanced functional biocompatible foam used as a hemostatic agent for compressible and non-compressible acute wounds |
JP5820815B2 (en) | 2009-12-15 | 2015-11-24 | インセプト・リミテッド・ライアビリティ・カンパニーIncept,Llc | Implants and biodegradable fiducial markers |
CA2782863A1 (en) | 2009-12-22 | 2011-06-30 | Lifebond Ltd | Modification of enzymatic crosslinkers for controlling properties of crosslinked matrices |
GB201008404D0 (en) * | 2010-05-20 | 2010-07-07 | Fujifilm Mfg Europe Bv | Hemostatic compositions |
ES2567174T3 (en) | 2010-08-05 | 2016-04-20 | Lifebond Ltd | Dry composition in dressings and wound adhesives |
KR101272484B1 (en) * | 2011-01-19 | 2013-06-10 | 세원셀론텍(주) | A radiation crosslinked collagen gel, its manufacture and its usage method |
WO2012100091A2 (en) | 2011-01-19 | 2012-07-26 | Accessclosure, Inc. | Apparatus and methods for sealing a vascular puncture |
US9820728B2 (en) | 2011-01-19 | 2017-11-21 | Access Closure, Inc. | Apparatus and methods for sealing a vascular puncture |
US9447169B2 (en) | 2011-03-04 | 2016-09-20 | Orthovita, Inc. | Flowable collagen-based hemostat and methods of use |
EP2694660B1 (en) | 2011-04-03 | 2018-08-08 | The General Hospital Corporation | Efficient protein expression in vivo using modified rna (mod-rna) |
EP3456200B1 (en) | 2011-05-10 | 2023-05-03 | Next Science IP Holdings Pty Ltd | Article having an antimicrobial solid and use thereof |
US9386968B2 (en) | 2011-05-11 | 2016-07-12 | Access Closure, Inc. | Apparatus and methods for sealing a vascular puncture |
US9561262B2 (en) | 2011-06-06 | 2017-02-07 | Phasebio Pharmaceuticals, Inc. | Use of modified vasoactive intestinal peptides in the treatment of hypertension |
US9205150B2 (en) | 2011-12-05 | 2015-12-08 | Incept, Llc | Medical organogel processes and compositions |
US20130202656A1 (en) | 2012-02-03 | 2013-08-08 | Dynasil Biomedical Corporation | Systems and kits for the fabrication of tissue patches |
US9757105B2 (en) | 2012-03-23 | 2017-09-12 | Accessclosure, Inc. | Apparatus and methods for sealing a vascular puncture |
US8721680B2 (en) | 2012-03-23 | 2014-05-13 | Accessclosure, Inc. | Apparatus and methods for sealing a vascular puncture |
KR20130134447A (en) * | 2012-05-31 | 2013-12-10 | 리젠프라임 주식회사 | New nanofiber membrane and manufacturing method thereof |
CA2914610C (en) | 2013-03-13 | 2022-08-02 | University Of Maryland | Advanced functional biocompatible polymer putty used as a hemostatic agent for treating damaged tissue and cells |
CA2947982C (en) | 2014-05-08 | 2022-11-29 | Phasebio Pharmaceuticals, Inc. | Methods and compositions for treating cystic fibrosis |
CA2955357A1 (en) * | 2014-07-17 | 2016-01-21 | The Regents Of The University Of California | Self-annealing microgel particles for biomedical applications |
RU2606990C2 (en) * | 2014-12-26 | 2017-01-10 | Общество с ограниченной ответственностью "Проект Экопак" | Biodegradable substance based on renewable raw material |
AU2016219513B2 (en) | 2015-02-09 | 2021-09-30 | Immunoforge Co., Ltd. | Methods and compositions for treating muscle disease and disorders |
US9833538B2 (en) | 2015-08-07 | 2017-12-05 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
AU2016307447A1 (en) | 2015-08-07 | 2018-02-22 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
US9540548B1 (en) | 2015-08-07 | 2017-01-10 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
US11931480B2 (en) | 2016-02-16 | 2024-03-19 | The Regents Of The University Of California | Microporous annealed particle gels and methods of use |
WO2017149584A1 (en) * | 2016-02-29 | 2017-09-08 | 川澄化学工業株式会社 | Adhesion prevention material |
RU2628809C1 (en) * | 2016-06-30 | 2017-08-22 | Федеральное государственное бюджетное учреждение Гематологический научный центр Министерства здравоохранения Российской Федерации (ФГБУ ГНЦ Минздрава России) | Hemostatic sponge and method of its production |
CA3051055A1 (en) | 2016-12-29 | 2018-07-26 | Tempo Therapeutics, Inc. | Methods and systems for treating a site of a medical implant |
US11679177B2 (en) | 2017-08-08 | 2023-06-20 | Baxter International Inc. | Polymeric compositions, delivery devices, and methods |
ES2902773T3 (en) | 2017-11-03 | 2022-03-29 | Baxter Int | Polymeric Compositions, Delivery Devices, and Methods |
KR102524418B1 (en) * | 2017-12-29 | 2023-04-24 | 마텍스 랩 에스.피.에이 | Method for preparing a filler comprising a neutralization step and having a hyaluronic acid base |
CA3083064A1 (en) | 2017-12-29 | 2019-07-04 | Baxter International Inc. | Spray-dried thrombin and methods of using and making spray-dried thrombin |
JP7043369B2 (en) * | 2018-08-24 | 2022-03-29 | 日立Geニュークリア・エナジー株式会社 | Radiation-resistant hydrogel material and its manufacturing method |
JP7042730B2 (en) | 2018-10-31 | 2022-03-28 | 株式会社ハイレックスコーポレーション | In vivo non-degradable adhesion inhibitor |
CN109529098A (en) * | 2018-12-03 | 2019-03-29 | 广州润虹医药科技股份有限公司 | A kind of surgery adhesive of medical |
US11739166B2 (en) | 2020-07-02 | 2023-08-29 | Davol Inc. | Reactive polysaccharide-based hemostatic agent |
KR102441137B1 (en) * | 2022-02-07 | 2022-09-06 | 김환철 | A biocompatible polymer hydrogel comprising an ether group capable of controlling the degradation rate |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986000912A1 (en) * | 1984-07-23 | 1986-02-13 | Pharmacia Ab | Gel for preventing adhesion between body tissues and process for its production |
EP0376931A1 (en) * | 1984-12-24 | 1990-07-04 | Collagen Corporation | Process for making collagen membranous materials for medical use |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4013078A (en) * | 1974-11-25 | 1977-03-22 | Feild James Rodney | Intervertebral protector means |
DE3036033A1 (en) * | 1980-09-24 | 1982-05-06 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | POWDERED WOUND TREATMENT AND METHOD FOR THE PRODUCTION THEREOF |
DE3105624A1 (en) * | 1981-02-16 | 1982-09-02 | Hormon-Chemie München GmbH, 8000 München | MATERIAL FOR SEALING AND HEALING Wounds |
JPS60222045A (en) * | 1984-04-20 | 1985-11-06 | 日立化成工業株式会社 | Blood vessel closure agent |
GB8422950D0 (en) * | 1984-09-11 | 1984-10-17 | Warne K J | Hydrogel |
JPS61122222A (en) * | 1984-11-19 | 1986-06-10 | Koken:Kk | Hemostatic agent composed of collagen or gelatin and protamine |
US5007916A (en) * | 1985-08-22 | 1991-04-16 | Johnson & Johnson Medical, Inc. | Method and material for prevention of surgical adhesions |
US4803075A (en) * | 1986-06-25 | 1989-02-07 | Collagen Corporation | Injectable implant composition having improved intrudability |
US5080893A (en) * | 1988-05-31 | 1992-01-14 | University Of Florida | Method for preventing surgical adhesions using a dilute solution of polymer |
US5017229A (en) * | 1990-06-25 | 1991-05-21 | Genzyme Corporation | Water insoluble derivatives of hyaluronic acid |
US5350573A (en) * | 1988-05-31 | 1994-09-27 | University Of Florida Research Foundation, Inc. | Method and composition for preventing surgical adhesions |
US5140016A (en) * | 1988-05-31 | 1992-08-18 | University Of Florida | Method and composition for preventing surgical adhesions using a dilute solution of polymer |
US5126141A (en) * | 1988-11-16 | 1992-06-30 | Mediventures Incorporated | Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides |
US5135751A (en) * | 1988-11-16 | 1992-08-04 | Mediventures Incorporated | Composition for reducing postsurgical adhesions |
US4891359A (en) * | 1988-12-08 | 1990-01-02 | Johnson & Johnson Patient Care, Inc. | Hemostatic collagen paste composition |
US5196185A (en) * | 1989-09-11 | 1993-03-23 | Micro-Collagen Pharmaceutics, Ltd. | Collagen-based wound dressing and method for applying same |
US5061274A (en) * | 1989-12-04 | 1991-10-29 | Kensey Nash Corporation | Plug device for sealing openings and method of use |
US5219328A (en) * | 1990-01-03 | 1993-06-15 | Cryolife, Inc. | Fibrin sealant delivery method |
US5134229A (en) * | 1990-01-12 | 1992-07-28 | Johnson & Johnson Medical, Inc. | Process for preparing a neutralized oxidized cellulose product and its method of use |
JPH0813750B2 (en) * | 1990-03-01 | 1996-02-14 | 持田製薬株式会社 | Oral thrombin formulation |
US5634943A (en) * | 1990-07-12 | 1997-06-03 | University Of Miami | Injectable polyethylene oxide gel implant and method for production |
US5192300A (en) * | 1990-10-01 | 1993-03-09 | Quinton Instrument Company | Insertion assembly and method of inserting a vessel plug into the body of a patient |
US5108421A (en) * | 1990-10-01 | 1992-04-28 | Quinton Instrument Company | Insertion assembly and method of inserting a vessel plug into the body of a patient |
US5129882A (en) * | 1990-12-27 | 1992-07-14 | Novoste Corporation | Wound clotting device and method of using same |
US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
NL9101051A (en) * | 1991-06-18 | 1993-01-18 | Ashridge Ag | CLOSING DEVICE FOR A VESSEL OR THE LIKE. |
ATE208217T1 (en) * | 1992-02-28 | 2001-11-15 | Cohesion Tech Inc | INJECTABLE CERAMIC COMPOUNDS AND METHOD FOR THEIR PRODUCTION AND USE |
US5204382A (en) * | 1992-02-28 | 1993-04-20 | Collagen Corporation | Injectable ceramic compositions and methods for their preparation and use |
US5468505A (en) * | 1992-02-28 | 1995-11-21 | Board Of Regents, The University Of Texas System | Local delivery of fibrinolysis enhancing agents |
ATE193037T1 (en) * | 1992-02-28 | 2000-06-15 | Collagen Corp | HIGHLY CONCENTRATED HOMOGENIZED COLLAGEN COMPOSITIONS |
WO1993021844A1 (en) * | 1992-04-23 | 1993-11-11 | Scimed Life Systems, Inc. | Apparatus and method for sealing vascular punctures |
US5413571A (en) * | 1992-07-16 | 1995-05-09 | Sherwood Medical Company | Device for sealing hemostatic incisions |
ATE206602T1 (en) * | 1992-11-12 | 2001-10-15 | Neville Alleyne | DEVICE FOR PROTECTING THE HEART |
JP3639593B2 (en) * | 1993-05-31 | 2005-04-20 | 科研製薬株式会社 | Cross-linked gelatin gel preparation containing basic fibroblast growth factor |
FR2715309B1 (en) * | 1994-01-24 | 1996-08-02 | Imedex | Adhesive composition, for surgical use, based on collagen modified by oxidative cutting and not crosslinked. |
US5531759A (en) * | 1994-04-29 | 1996-07-02 | Kensey Nash Corporation | System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating |
US5599735A (en) * | 1994-08-01 | 1997-02-04 | Texas Instruments Incorporated | Method for doped shallow junction formation using direct gas-phase doping |
US5516532A (en) * | 1994-08-05 | 1996-05-14 | Children's Medical Center Corporation | Injectable non-immunogenic cartilage and bone preparation |
US5677284A (en) * | 1995-06-06 | 1997-10-14 | Regen Biologics, Inc. | Charged collagen particle-based delivery matrix |
US5902832A (en) * | 1996-08-20 | 1999-05-11 | Menlo Care, Inc. | Method of synthesizing swollen hydrogel for sphincter augmentation |
US6063061A (en) * | 1996-08-27 | 2000-05-16 | Fusion Medical Technologies, Inc. | Fragmented polymeric compositions and methods for their use |
-
1997
- 1997-07-31 US US08/903,674 patent/US6063061A/en not_active Expired - Lifetime
- 1997-08-14 RU RU99106523/14A patent/RU2207882C2/en not_active IP Right Cessation
- 1997-08-14 BR BRPI9711241A patent/BR9711241B8/en not_active IP Right Cessation
- 1997-08-14 DE DE69720479T patent/DE69720479T2/en not_active Expired - Lifetime
- 1997-08-14 WO PCT/US1997/015262 patent/WO1998008550A1/en active IP Right Grant
- 1997-08-14 IL IL12849697A patent/IL128496A/en not_active IP Right Cessation
- 1997-08-14 JP JP51197098A patent/JP4418535B2/en not_active Expired - Lifetime
- 1997-08-14 AU AU42412/97A patent/AU719534B2/en not_active Expired
- 1997-08-14 CA CA002264647A patent/CA2264647C/en not_active Expired - Lifetime
- 1997-08-14 EP EP97940692A patent/EP0927053B1/en not_active Expired - Lifetime
-
2006
- 2006-06-06 JP JP2006157904A patent/JP4842713B2/en not_active Expired - Lifetime
-
2009
- 2009-08-12 JP JP2009187571A patent/JP4843079B2/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986000912A1 (en) * | 1984-07-23 | 1986-02-13 | Pharmacia Ab | Gel for preventing adhesion between body tissues and process for its production |
EP0376931A1 (en) * | 1984-12-24 | 1990-07-04 | Collagen Corporation | Process for making collagen membranous materials for medical use |
Cited By (127)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8512729B2 (en) | 1996-08-27 | 2013-08-20 | Baxter International Inc. | Fragmented polymeric compositions and methods for their use |
US7871637B2 (en) | 1996-08-27 | 2011-01-18 | Baxter International Inc. | Dry hemostatic compositions and methods for their preparation |
US7320962B2 (en) | 1996-08-27 | 2008-01-22 | Baxter International Inc. | Hemoactive compositions and methods for their manufacture and use |
US8603511B2 (en) | 1996-08-27 | 2013-12-10 | Baxter International, Inc. | Fragmented polymeric compositions and methods for their use |
US8303981B2 (en) | 1996-08-27 | 2012-11-06 | Baxter International Inc. | Fragmented polymeric compositions and methods for their use |
US8357378B2 (en) | 1996-08-27 | 2013-01-22 | Baxter International Inc. | Fragmented polymeric compositions and methods for their use |
EP1109498A1 (en) * | 1998-08-04 | 2001-06-27 | Fusion Medical Technologies, Inc. | Percutaneous tissue track closure assembly and method |
EP1109498A4 (en) * | 1998-08-04 | 2003-01-08 | Fusion Medical Technologies | Percutaneous tissue track closure assembly and method |
WO2000032225A1 (en) * | 1998-12-03 | 2000-06-08 | University College London | Tissue repair |
JP2003501215A (en) * | 1999-06-10 | 2003-01-14 | フュージョン メディカル テクノロジーズ, インコーポレイテッド | Blood active compositions and methods for their manufacture and use |
US6706690B2 (en) | 1999-06-10 | 2004-03-16 | Baxter Healthcare Corporation | Hemoactive compositions and methods for their manufacture and use |
JP2010148922A (en) * | 1999-06-10 | 2010-07-08 | Fusion Medical Technologies Inc | Hemoactive composition, and method for production and use thereof |
WO2000076533A1 (en) | 1999-06-10 | 2000-12-21 | Fusion Medical Technologies, Inc. | Hemoactive compositions and methods for their manufacture and use |
JP2003516775A (en) * | 1999-09-13 | 2003-05-20 | ケラプラスト テクノロジーズ, リミテッド | Implantable prosthesis or tissue expansion device |
EP1274369A2 (en) * | 1999-09-13 | 2003-01-15 | Keraplast Technologies Ltd. | Implantable prosthetic or tissue expanding device |
EP1274369A4 (en) * | 1999-09-13 | 2009-04-29 | Keraplast Tech Ltd | Implantable prosthetic or tissue expanding device |
WO2002074356A1 (en) * | 2001-03-16 | 2002-09-26 | Vivoxid Oy | Composite for attaching, growing and/or repairing of living tissues and use of said composite |
US8383141B2 (en) | 2001-07-17 | 2013-02-26 | Baxter International Inc. | Dry hemostatic compositions and methods for their preparation |
US8092820B2 (en) | 2001-07-17 | 2012-01-10 | Baxter International Inc. | Dry hemostatic compositions and methods for their preparation |
US7001988B2 (en) | 2001-09-25 | 2006-02-21 | Keraplast Technologies, Ltd. | Methods for controlling peptide solubility, chemically modified peptides, and stable solvent systems for producing same |
US8324346B2 (en) | 2002-01-28 | 2012-12-04 | Keraplast Technologies, Ltd. | Bioactive keratin peptides |
US7501485B2 (en) | 2002-01-28 | 2009-03-10 | Keraplast Technologies, Ltd. | Bioactive keratin peptides |
US6989437B2 (en) | 2002-04-10 | 2006-01-24 | Keraplast Technologies, Ltd. | Methods for producing, films comprising, and methods for using heterogeneous crosslinked protein networks |
US6914126B2 (en) | 2002-04-10 | 2005-07-05 | Keraplast Technologies, Ltd. | Methods for producing, films comprising, and methods for using heterogenous crosslinked protein networks |
US7001987B2 (en) | 2002-04-22 | 2006-02-21 | Keraplast Technologies, Ltd. | Hydrogel with controllable mechanical, chemical, and biological properties and method for making same |
US8846075B2 (en) | 2003-01-24 | 2014-09-30 | Magle Holding Ab | Composition material for transmucosal delivery |
US8834864B2 (en) | 2003-06-05 | 2014-09-16 | Baxter International Inc. | Methods for repairing and regenerating human dura mater |
US8551941B2 (en) | 2003-08-07 | 2013-10-08 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
US7833965B2 (en) | 2003-08-07 | 2010-11-16 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
US7718412B2 (en) | 2003-08-07 | 2010-05-18 | Ethicon, Inc. | Hemostatic compositions containing sterile thrombin |
US7927626B2 (en) | 2003-08-07 | 2011-04-19 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
US9005609B2 (en) | 2003-08-07 | 2015-04-14 | Ethicon, Inc. | Hemostatic compositions containing sterile thrombin |
US8440225B2 (en) | 2003-08-07 | 2013-05-14 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
US7109163B2 (en) | 2004-01-30 | 2006-09-19 | Ethicon, Inc. | Hemostatic compositions and devices |
US11458226B2 (en) | 2004-04-08 | 2022-10-04 | Galderma Holding SA | Method of soft tissue augmentation |
US8119160B2 (en) | 2004-06-29 | 2012-02-21 | Ethicon, Inc. | Hemostatic compositions and devices |
US8637231B2 (en) | 2004-08-17 | 2014-01-28 | Wake Forest University Health Sciences | Method for increasing the volume of a blood substitute with an expander comprising basic alpha keratose |
WO2006113249A2 (en) * | 2005-04-12 | 2006-10-26 | Warsaw Orthopedic, Inc. | Methods and devices for preserving motion in an articulating prosthetic disc |
WO2006113249A3 (en) * | 2005-04-12 | 2007-08-02 | Warsaw Orthopedic Inc | Methods and devices for preserving motion in an articulating prosthetic disc |
US8257438B2 (en) | 2005-04-12 | 2012-09-04 | Warsaw Orthopedic, Inc. | Methods and devices for preserving motion in an articulating prosthetic disc |
AU2006236849B2 (en) * | 2005-04-12 | 2010-04-15 | Warsaw Orthopedic, Inc. | Methods and devices for preserving motion in an articulating prosthetic disc |
US8920827B2 (en) | 2005-10-21 | 2014-12-30 | Wake Forest University Health Sciences | Keratin bioceramic compositions |
US11173233B2 (en) | 2005-10-21 | 2021-11-16 | Wake Forest University Health Sciences | Keratin bioceramic compositions |
US8968764B2 (en) | 2006-02-10 | 2015-03-03 | Wake Forest University Health Sciences | Nerve regeneration employing keratin biomaterials |
US9968706B2 (en) | 2006-02-10 | 2018-05-15 | Wake Forest University Health Sciences | Nerve regeneration employing keratin biomaterials |
US10821211B2 (en) | 2006-02-17 | 2020-11-03 | Wake Forest University Health Sciences | Coatings and biomedical implants formed from keratin biomaterials |
US8299013B2 (en) | 2006-02-17 | 2012-10-30 | Wake Forest University Health Sciences | Clotting and healing compositions containing keratin biomaterials |
US9149566B2 (en) | 2006-02-17 | 2015-10-06 | Wake Forest University Health Sciences | Coatings and biomedical implants formed from keratin biomaterials |
US8273702B2 (en) | 2006-02-17 | 2012-09-25 | Wake Forest University Health Sciences | Wound healing compositions containing keratin biomaterials |
US8258093B2 (en) | 2006-02-17 | 2012-09-04 | Wake Forest University Health Sciences | Wound healing compositions containing keratin biomaterials |
US8703122B2 (en) | 2006-05-31 | 2014-04-22 | Baxter International Inc. | Method for directed cell in-growth and controlled tissue regeneration in spinal surgery |
US8962025B2 (en) | 2006-08-02 | 2015-02-24 | Baxter International Inc. | Rapidly acting dry sealant and methods for use and manufacture |
US9114172B2 (en) | 2006-08-02 | 2015-08-25 | Baxter International Inc. | Rapidly acting dry sealant and methods for use and manufacture |
FR2909285A1 (en) * | 2006-12-01 | 2008-06-06 | Anteis Sa | Use of an injectable or implantable antiadhesive antifibrotic gel based on a crosslinked natural or synthetic polymer for treating glaucoma or surgical wounds |
US9068162B2 (en) | 2007-08-17 | 2015-06-30 | Wake Forest University Health Sciences | Keratin biomaterials for cell culture and methods of use |
US8790698B2 (en) | 2007-10-30 | 2014-07-29 | Baxter International Inc. | Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects |
US9533069B2 (en) | 2008-02-29 | 2017-01-03 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
US9216188B2 (en) | 2008-09-04 | 2015-12-22 | The General Hospital Corporation | Hydrogels for vocal cord and soft tissue augmentation and repair |
US9682169B2 (en) | 2008-09-04 | 2017-06-20 | Massachusetts Institute Of Technology | Hydrogels for vocal cord and soft tissue augmentation and repair |
WO2010027471A3 (en) * | 2008-09-04 | 2010-07-08 | The General Hospital Corporation | Hydrogels for vocal cord and soft tissue augmentation and repair |
US9993298B2 (en) | 2009-05-18 | 2018-06-12 | Baxter International Inc. | Method for the improvement of mesh implant biocompatibility |
US9039783B2 (en) | 2009-05-18 | 2015-05-26 | Baxter International, Inc. | Method for the improvement of mesh implant biocompatibility |
US9162006B2 (en) | 2009-06-16 | 2015-10-20 | Baxter International Inc. | Hemostatic sponge |
US8771258B2 (en) | 2009-12-16 | 2014-07-08 | Baxter International Inc. | Hemostatic sponge |
US9517287B2 (en) | 2009-12-16 | 2016-12-13 | Baxter International, Inc. | Hemostatic sponge |
US9198568B2 (en) | 2010-03-04 | 2015-12-01 | The General Hospital Corporation | Methods and systems of matching voice deficits with a tunable mucosal implant to restore and enhance individualized human sound and voice production |
US10434213B2 (en) | 2010-03-05 | 2019-10-08 | Wake Forest University Health Sciences | Controlled delivery system |
US8545893B2 (en) | 2010-03-08 | 2013-10-01 | Wake Forest University Health Sciences | Keratin biomaterials for treatment of ischemia |
US10441674B2 (en) | 2010-04-07 | 2019-10-15 | Baxter International Inc. | Hemostatic sponge |
US11478566B2 (en) | 2010-04-07 | 2022-10-25 | Baxter International Inc. | Hemostatic sponge |
US8703170B2 (en) | 2010-04-07 | 2014-04-22 | Baxter International Inc. | Hemostatic sponge |
US9375505B2 (en) | 2010-04-07 | 2016-06-28 | Baxter International Inc. | Hemostatic sponge |
US10245348B2 (en) | 2010-06-01 | 2019-04-02 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
US10994045B2 (en) | 2010-06-01 | 2021-05-04 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
WO2011151384A1 (en) | 2010-06-01 | 2011-12-08 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
WO2011151386A1 (en) | 2010-06-01 | 2011-12-08 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
EP2575775B1 (en) | 2010-06-01 | 2018-04-04 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
WO2011151400A1 (en) | 2010-06-01 | 2011-12-08 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
EP2575770B1 (en) | 2010-06-01 | 2017-03-22 | Baxter International Inc | Process for making dry and stable hemostatic compositions |
EP2575776B1 (en) | 2010-06-01 | 2018-05-30 | Baxter International Inc | Process for making dry and stable hemostatic compositions |
US8940335B2 (en) | 2010-06-01 | 2015-01-27 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
US9408945B2 (en) | 2010-06-01 | 2016-08-09 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
US9084728B2 (en) | 2010-06-01 | 2015-07-21 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
CN103209716A (en) * | 2010-09-21 | 2013-07-17 | 学校法人同志社 | Suture reinforcing material being for use in automatic suturing devices and containing hydrophilic polymer |
US9220754B2 (en) | 2010-11-17 | 2015-12-29 | Wake Forest University Health Sciences | Keratin compositions for treatment of bone deficiency or injury |
US11154481B2 (en) | 2011-02-03 | 2021-10-26 | Q-Med Ab | Hyaluronic acid composition |
US10098961B2 (en) | 2011-02-03 | 2018-10-16 | Q-Med Ab | Hyaluronic acid composition |
EP2726115B1 (en) | 2011-06-30 | 2017-09-13 | Ethicon, Inc | Procoagulant peptides and their derivatives and uses therefor |
CN103732265A (en) * | 2011-08-02 | 2014-04-16 | 大日精化工业株式会社 | Anti-adhesion medical material and method for producing same |
EP2740499A4 (en) * | 2011-08-02 | 2015-06-10 | Dainichiseika Color Chem | Anti-adhesion medical material and method for producing same |
WO2013053749A3 (en) * | 2011-10-11 | 2013-11-14 | Baxter International Inc. | Hemostatic compositions |
EP4137165A1 (en) | 2011-10-11 | 2023-02-22 | Baxter International Inc. | Hemostatic compositions |
WO2013053759A2 (en) | 2011-10-11 | 2013-04-18 | Baxter International Inc. | Hemostatic compositions |
WO2013053753A2 (en) | 2011-10-11 | 2013-04-18 | Baxter International Inc. | Hemostatic composition |
WO2013053755A2 (en) | 2011-10-11 | 2013-04-18 | Baxter International Inc. | Hemostatic compositions |
US9821025B2 (en) | 2011-10-11 | 2017-11-21 | Baxter International Inc. | Hemostatic compositions |
WO2013053749A2 (en) | 2011-10-11 | 2013-04-18 | Baxter International Inc. | Hemostatic compositions |
EP4137166A1 (en) | 2011-10-11 | 2023-02-22 | Baxter International Inc | Hemostatic compositions |
US10322170B2 (en) | 2011-10-11 | 2019-06-18 | Baxter International Inc. | Hemostatic compositions |
EP4137164A1 (en) | 2011-10-11 | 2023-02-22 | Baxter International Inc. | Hemostatic compositions |
WO2013060770A1 (en) | 2011-10-27 | 2013-05-02 | Baxter International Inc. | Hemostatic compositions |
CN103889447B (en) * | 2011-10-27 | 2015-11-25 | 巴克斯特国际公司 | hemostatic composition |
CN103889447A (en) * | 2011-10-27 | 2014-06-25 | 巴克斯特国际公司 | Hemostatic compositions |
WO2013060769A2 (en) | 2011-10-27 | 2013-05-02 | Baxter International Inc. | Hemostatic compositions |
AU2012330450B2 (en) * | 2011-10-27 | 2017-04-27 | Baxter Healthcare Sa | Hemostatic compositions |
US9833541B2 (en) | 2011-10-27 | 2017-12-05 | Baxter International Inc. | Hemostatic compositions |
US11109849B2 (en) | 2012-03-06 | 2021-09-07 | Ferrosan Medical Devices A/S | Pressurized container containing haemostatic paste |
US9999703B2 (en) | 2012-06-12 | 2018-06-19 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
US9265858B2 (en) | 2012-06-12 | 2016-02-23 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
US10799611B2 (en) | 2012-06-12 | 2020-10-13 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
US10595837B2 (en) | 2013-06-21 | 2020-03-24 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
US9724078B2 (en) | 2013-06-21 | 2017-08-08 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
US11103616B2 (en) | 2013-12-11 | 2021-08-31 | Ferrosan Medical Devices A/S | Dry composition comprising an extrusion enhancer |
US10111980B2 (en) | 2013-12-11 | 2018-10-30 | Ferrosan Medical Devices A/S | Dry composition comprising an extrusion enhancer |
US11046818B2 (en) | 2014-10-13 | 2021-06-29 | Ferrosan Medical Devices A/S | Dry composition for use in haemostasis and wound healing |
US10653837B2 (en) | 2014-12-24 | 2020-05-19 | Ferrosan Medical Devices A/S | Syringe for retaining and mixing first and second substances |
CN104861179B (en) * | 2015-06-03 | 2017-09-12 | 西北师范大学 | The preparation and the application as pharmaceutical carrier of a kind of feather keratin sodium alginate composite high-molecular sensitive hydrogel |
CN104861179A (en) * | 2015-06-03 | 2015-08-26 | 西北师范大学 | Preparation for feather keratin and sodium alginate composite polymer double-sensitive hydrogel and application therefore as drug carrier |
CN104892864A (en) * | 2015-06-03 | 2015-09-09 | 西北师范大学 | Preparation of keratin-sodium alginate composite microporous gel and application of gel as drug carrier |
US10918796B2 (en) | 2015-07-03 | 2021-02-16 | Ferrosan Medical Devices A/S | Syringe for mixing two components and for retaining a vacuum in a storage condition |
US10751444B2 (en) | 2015-08-07 | 2020-08-25 | Victor Matthew Phillips | Flowable hemostatic gel composition and its methods of use |
US10660945B2 (en) | 2015-08-07 | 2020-05-26 | Victor Matthew Phillips | Flowable hemostatic gel composition and its methods of use |
EP3943127A1 (en) | 2015-09-01 | 2022-01-26 | Baxter International Inc | Hemostatic material |
CN108314790A (en) * | 2018-03-16 | 2018-07-24 | 东华大学 | A kind of photo-crosslinking thio chitosan-polyethylene glycol methacrylate-styrene polymer hydrogel and preparation method thereof for tissue adhesive |
CN108498871A (en) * | 2018-03-23 | 2018-09-07 | 中南大学湘雅二医院 | A kind of preparation of autologous organisms protein hydrogel and its application in ophthalmology |
CN108853598A (en) * | 2018-03-23 | 2018-11-23 | 中南大学湘雅二医院 | A kind of preparation of autologous organisms protein hydrogel and its application in operation on retina |
US11801324B2 (en) | 2018-05-09 | 2023-10-31 | Ferrosan Medical Devices A/S | Method for preparing a haemostatic composition |
Also Published As
Publication number | Publication date |
---|---|
AU4241297A (en) | 1998-03-19 |
JP2009256391A (en) | 2009-11-05 |
DE69720479D1 (en) | 2003-05-08 |
CA2264647A1 (en) | 1998-03-05 |
JP4842713B2 (en) | 2011-12-21 |
JP2002515086A (en) | 2002-05-21 |
BR9711241A (en) | 1999-08-17 |
IL128496A (en) | 2004-06-20 |
RU2207882C2 (en) | 2003-07-10 |
BR9711241B8 (en) | 2021-06-22 |
JP4843079B2 (en) | 2011-12-21 |
CA2264647C (en) | 2009-11-24 |
BRPI9711241B1 (en) | 2016-12-20 |
JP2006231090A (en) | 2006-09-07 |
DE69720479T2 (en) | 2004-03-04 |
EP0927053A1 (en) | 1999-07-07 |
JP4418535B2 (en) | 2010-02-17 |
EP0927053B1 (en) | 2003-04-02 |
US6063061A (en) | 2000-05-16 |
AU719534B2 (en) | 2000-05-11 |
IL128496A0 (en) | 2000-01-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0927053B1 (en) | Fragmented polymeric hydrogels for adhesion prevention and their preparation | |
US6066325A (en) | Fragmented polymeric compositions and methods for their use | |
US8603511B2 (en) | Fragmented polymeric compositions and methods for their use | |
US8303981B2 (en) | Fragmented polymeric compositions and methods for their use | |
US10159742B2 (en) | Hydrogel compositions | |
US7320962B2 (en) | Hemoactive compositions and methods for their manufacture and use | |
EP1185288B1 (en) | Hemoactive compositions and methods for their manufacture and use | |
EP2498763A1 (en) | Polysaccharide based hydrogels | |
KR20020011955A (en) | A conglutination inhibitor | |
JP2011046749A (en) | Fragmented polymeric hydrogel for adhesion prevention, and preparation thereof | |
US20230355829A1 (en) | Water activated hydrogel-based medical patches, and methods of making and using such patches |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH HU IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW AM AZ BY KG KZ MD RU TJ TM |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH KE LS MW SD SZ UG ZW AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
ENP | Entry into the national phase |
Ref document number: 2264647 Country of ref document: CA Ref country code: JP Ref document number: 1998 511970 Kind code of ref document: A Format of ref document f/p: F Ref country code: CA Ref document number: 2264647 Kind code of ref document: A Format of ref document f/p: F |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1997940692 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWP | Wipo information: published in national office |
Ref document number: 1997940692 Country of ref document: EP |
|
WWG | Wipo information: grant in national office |
Ref document number: 1997940692 Country of ref document: EP |