WO1998017315A3 - Permeation enhancers for transdermal drug delivery compositions, devices, and methods - Google Patents
Permeation enhancers for transdermal drug delivery compositions, devices, and methods Download PDFInfo
- Publication number
- WO1998017315A3 WO1998017315A3 PCT/US1997/018956 US9718956W WO9817315A3 WO 1998017315 A3 WO1998017315 A3 WO 1998017315A3 US 9718956 W US9718956 W US 9718956W WO 9817315 A3 WO9817315 A3 WO 9817315A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- drug
- permeation enhancer
- methods
- drug delivery
- devices
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU49907/97A AU4990797A (en) | 1996-10-24 | 1997-10-23 | Permeation enhancers for transdermal drug delivery compositions, devices, and methods |
DK97912815T DK0934078T3 (en) | 1996-10-24 | 1997-10-23 | Permeability promoters for transdermal administration of active substances, devices and processes for their preparation |
CA002264687A CA2264687C (en) | 1996-10-24 | 1997-10-23 | Permeation enhancers for transdermal drug delivery compositions, devices, and methods |
JP10519563A JP2001502693A (en) | 1996-10-24 | 1997-10-23 | Permeation enhancers suitable for transdermal drug administration compositions, devices, and methods |
AT97912815T ATE229817T1 (en) | 1996-10-24 | 1997-10-23 | PENETRATION-PROMOTING SUBSTANCES FOR THE TRANSDERMAL ADMINISTRATION OF ACTIVE INGREDIENTS, DEVICES AND METHOD FOR THE PRODUCTION |
EP97912815A EP0934078B1 (en) | 1996-10-24 | 1997-10-23 | Permeation enhancers for transdermal drug delivery compositions, devices, and methods |
DE69718037T DE69718037T2 (en) | 1996-10-24 | 1997-10-23 | PENETRATION-PROMOTING SUBSTANCES FOR THE TRANSDERMAL ADMINISTRATION OF ACTIVE SUBSTANCES, DEVICES AND METHODS FOR THE PRODUCTION THEREOF |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3042496P | 1996-10-24 | 1996-10-24 | |
US60/030,424 | 1996-10-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998017315A2 WO1998017315A2 (en) | 1998-04-30 |
WO1998017315A3 true WO1998017315A3 (en) | 1998-07-02 |
Family
ID=21854141
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/018956 WO1998017315A2 (en) | 1996-10-24 | 1997-10-23 | Permeation enhancers for transdermal drug delivery compositions, devices, and methods |
Country Status (10)
Country | Link |
---|---|
US (1) | US6004578A (en) |
EP (1) | EP0934078B1 (en) |
JP (1) | JP2001502693A (en) |
AT (1) | ATE229817T1 (en) |
AU (1) | AU4990797A (en) |
CA (1) | CA2264687C (en) |
DE (1) | DE69718037T2 (en) |
DK (1) | DK0934078T3 (en) |
ES (1) | ES2191834T3 (en) |
WO (1) | WO1998017315A2 (en) |
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US9526763B2 (en) | 2005-02-03 | 2016-12-27 | Intarcia Therapeutics Inc. | Solvent/polymer solutions as suspension vehicles |
US9539200B2 (en) | 2005-02-03 | 2017-01-10 | Intarcia Therapeutics Inc. | Two-piece, internal-channel osmotic delivery system flow modulator |
US9572889B2 (en) | 2008-02-13 | 2017-02-21 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
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- 1997-10-23 EP EP97912815A patent/EP0934078B1/en not_active Expired - Lifetime
- 1997-10-23 AT AT97912815T patent/ATE229817T1/en not_active IP Right Cessation
- 1997-10-23 AU AU49907/97A patent/AU4990797A/en not_active Abandoned
- 1997-10-23 US US08/956,379 patent/US6004578A/en not_active Expired - Lifetime
- 1997-10-23 CA CA002264687A patent/CA2264687C/en not_active Expired - Fee Related
- 1997-10-23 DE DE69718037T patent/DE69718037T2/en not_active Expired - Fee Related
- 1997-10-23 JP JP10519563A patent/JP2001502693A/en not_active Ceased
- 1997-10-23 DK DK97912815T patent/DK0934078T3/en active
- 1997-10-23 ES ES97912815T patent/ES2191834T3/en not_active Expired - Lifetime
- 1997-10-23 WO PCT/US1997/018956 patent/WO1998017315A2/en active IP Right Grant
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US9526763B2 (en) | 2005-02-03 | 2016-12-27 | Intarcia Therapeutics Inc. | Solvent/polymer solutions as suspension vehicles |
US9539200B2 (en) | 2005-02-03 | 2017-01-10 | Intarcia Therapeutics Inc. | Two-piece, internal-channel osmotic delivery system flow modulator |
US9572889B2 (en) | 2008-02-13 | 2017-02-21 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
Also Published As
Publication number | Publication date |
---|---|
JP2001502693A (en) | 2001-02-27 |
ES2191834T3 (en) | 2003-09-16 |
EP0934078A2 (en) | 1999-08-11 |
WO1998017315A2 (en) | 1998-04-30 |
AU4990797A (en) | 1998-05-15 |
CA2264687C (en) | 2006-04-25 |
US6004578A (en) | 1999-12-21 |
DE69718037D1 (en) | 2003-01-30 |
EP0934078B1 (en) | 2002-12-18 |
CA2264687A1 (en) | 1998-04-30 |
DK0934078T3 (en) | 2003-04-14 |
ATE229817T1 (en) | 2003-01-15 |
DE69718037T2 (en) | 2003-07-10 |
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