WO1998039094A1 - Matrices for separation and separation exploiting said matrices - Google Patents
Matrices for separation and separation exploiting said matrices Download PDFInfo
- Publication number
- WO1998039094A1 WO1998039094A1 PCT/SE1998/000387 SE9800387W WO9839094A1 WO 1998039094 A1 WO1998039094 A1 WO 1998039094A1 SE 9800387 W SE9800387 W SE 9800387W WO 9839094 A1 WO9839094 A1 WO 9839094A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polymer
- matrix according
- groups
- matrix
- particles
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/282—Porous sorbents
- B01J20/285—Porous sorbents based on polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
- B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/34—Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
- G01N2030/524—Physical parameters structural properties
- G01N2030/528—Monolithic sorbent material
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69832166T DE69832166T2 (en) | 1997-03-04 | 1998-03-04 | MATRIX FOR SEPARATION AND USE OF MATRIX FOR SEPARATION |
CA002281846A CA2281846C (en) | 1997-03-04 | 1998-03-04 | Matrices for separation and separation exploiting said matrices |
JP53844798A JP4135812B2 (en) | 1997-03-04 | 1998-03-04 | Separation matrix and separation method using the matrix |
US09/380,050 US6572766B1 (en) | 1997-03-04 | 1998-03-04 | Matrices for separation and separation exploiting said matrices |
AT98908407T ATE308380T1 (en) | 1997-03-04 | 1998-03-04 | MATRIX FOR SEPARATION AND USE OF THE MATRIX FOR SEPARATION |
AU66442/98A AU729313B2 (en) | 1997-03-04 | 1998-03-04 | Matrices for separation and separation exploiting said matrices |
EP98908407A EP0980288B1 (en) | 1997-03-04 | 1998-03-04 | Matrices for separation and separation exploiting said matrices |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9700769-4 | 1997-03-04 | ||
SE9700769A SE9700769D0 (en) | 1997-03-04 | 1997-03-04 | Matrices for separation and separation that utilize the matrices |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998039094A1 true WO1998039094A1 (en) | 1998-09-11 |
Family
ID=20406014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SE1998/000387 WO1998039094A1 (en) | 1997-03-04 | 1998-03-04 | Matrices for separation and separation exploiting said matrices |
Country Status (10)
Country | Link |
---|---|
US (1) | US6572766B1 (en) |
EP (1) | EP0980288B1 (en) |
JP (1) | JP4135812B2 (en) |
AT (1) | ATE308380T1 (en) |
AU (1) | AU729313B2 (en) |
CA (1) | CA2281846C (en) |
DE (1) | DE69832166T2 (en) |
ES (1) | ES2251766T3 (en) |
SE (1) | SE9700769D0 (en) |
WO (1) | WO1998039094A1 (en) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001037987A1 (en) * | 1999-11-25 | 2001-05-31 | Amersham Biosciences Ab | A method for selective removal of a substance from samples containing compounds having nucleic acid structure |
US6602990B1 (en) * | 1996-04-11 | 2003-08-05 | Amersham Biosciences Ab | Process for the production of a porous cross-linked polysaccharide gel and its use as a gel filtration media and in chromatography |
WO2004011141A1 (en) * | 2002-07-26 | 2004-02-05 | Applera Corporation | Size-exclusion ion-exchange particles |
WO2004020994A1 (en) * | 2002-08-27 | 2004-03-11 | Amersham Biosciences Ab | Chromatographic two-layer particles |
EP1715953A1 (en) * | 2004-02-18 | 2006-11-02 | Applera Corporation | Polyelectrolyte-coated size-exclusion ion-exchange particles |
US7347976B2 (en) | 2001-12-20 | 2008-03-25 | 3M Innovative Properties Company | Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix |
WO2010027696A1 (en) * | 2008-08-25 | 2010-03-11 | Ge Healthcare Bio-Sciences Corp. | Simple load and elute process for purification of genomic dna |
US7871827B2 (en) | 2001-12-20 | 2011-01-18 | 3M Innovative Properties Company | Methods and devices for removal of organic molecules from biological mixtures using anion exchange |
US20110045574A1 (en) * | 2008-04-22 | 2011-02-24 | Jan Bergstrom | Chromatography medium |
US7939249B2 (en) | 2003-12-24 | 2011-05-10 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and concentration step |
US7981600B2 (en) * | 2003-04-17 | 2011-07-19 | 3M Innovative Properties Company | Methods and devices for removal of organic molecules from biological mixtures using an anion exchange material that includes a polyoxyalkylene |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003049833A1 (en) * | 2001-11-27 | 2003-06-19 | Ciphergen Biosystems, Inc. | Composite chromatographic sorbent of mineral oxide beads with hydroxyapatite-filled pores |
US7473367B2 (en) * | 2002-06-26 | 2009-01-06 | Dionex Corporation | Monolithic column |
US6749749B2 (en) * | 2002-06-26 | 2004-06-15 | Isco, Inc. | Separation system, components of a separation system and methods of making and using them |
US20050061745A1 (en) * | 2002-06-26 | 2005-03-24 | Teledyne Isco, Inc. | Separation system, components of a separation system and methods of making and using them |
US20040016702A1 (en) * | 2002-07-26 | 2004-01-29 | Applera Corporation | Device and method for purification of nucleic acids |
US8137548B2 (en) * | 2003-10-17 | 2012-03-20 | Zirchrom Separations, Inc. | Chelator-modified inorganic oxide particles |
US20050196856A1 (en) * | 2004-02-18 | 2005-09-08 | Applera Corporation | Polyelectrolyte-coated size-exclusion ion-exchange particles |
US20050181378A1 (en) * | 2004-02-18 | 2005-08-18 | Applera Corporation | Polyelectrolyte-coated size-exclusion ion-exchange particles |
US20060160122A1 (en) * | 2004-02-18 | 2006-07-20 | Applera Corporation | Polyelectrolyte-coated size-exclusion ion-exchange particles |
SE0400490D0 (en) | 2004-02-26 | 2004-02-26 | Amersham Biosciences Ab | Plasmid purification |
SE0502485L (en) * | 2005-11-09 | 2007-05-10 | Peter Viberg | particles |
WO2007063701A1 (en) * | 2005-12-02 | 2007-06-07 | Sekisui Chemical Co., Ltd. | Hydrophilic polymer microparticle, filler for ion exchange liquid chromatography, and method for production of filler for ion exchange liquid chromatography |
US10562007B2 (en) * | 2007-07-25 | 2020-02-18 | Ge Healthcare Bioprocess R&D Ab | Separation matrix |
US20120156779A1 (en) * | 2009-08-27 | 2012-06-21 | Ge Healthcare Bio-Sciences Ab | Method for cell expansion |
WO2011035282A1 (en) * | 2009-09-21 | 2011-03-24 | Ge Healthcare Bio-Sciences Ab | Dual capture separation |
IN2012DN06243A (en) * | 2010-02-19 | 2015-09-25 | Ge Healthcare Bio Sciences Ab | |
US9259729B2 (en) * | 2010-04-26 | 2016-02-16 | Ge Healthcare Bio-Sciences Ab | Method for production of chromatography media |
JP5631271B2 (en) * | 2010-07-28 | 2014-11-26 | ローム アンド ハース カンパニーRohm And Haas Company | Method for making and using improved chromatographic media |
JP5474881B2 (en) * | 2010-07-28 | 2014-04-16 | ローム アンド ハース カンパニー | Method for making and using improved chromatographic media |
US20150328563A1 (en) * | 2012-12-14 | 2015-11-19 | Ge Healthcare Bio-Sciences Ab | Method for Cleaning of Packed Bed Chromatography Columns |
BR112015029051A2 (en) | 2013-05-20 | 2017-07-25 | Shantha Biotechnics Private Ltd | processes for purifying a polysaccharide protein conjugate and for manufacturing a vaccine |
US9731249B2 (en) * | 2014-04-15 | 2017-08-15 | Ut-Battelle, Llc | Polymeric molecular sieve membranes for gas separation |
WO2016117574A1 (en) * | 2015-01-19 | 2016-07-28 | 日立化成株式会社 | Separation material |
JP6746919B2 (en) * | 2016-01-15 | 2020-08-26 | 日立化成株式会社 | Separation material and column |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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US4535010A (en) * | 1982-10-18 | 1985-08-13 | Pharmacia Ab | Method of forming polymeric layers |
EP0221046A2 (en) * | 1985-11-01 | 1987-05-06 | Monsanto Company | Modified polymeric surfaces and process for preparing same |
US5030352A (en) * | 1990-01-25 | 1991-07-09 | Purdue Research Foundation | Coated media for chromatography |
WO1994009063A1 (en) * | 1992-10-21 | 1994-04-28 | Cornell Research Foundation, Inc. | Pore-size selective modification of porous materials |
Family Cites Families (24)
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US3959251A (en) | 1970-06-25 | 1976-05-25 | Exploaterings Aktiebolaget T.B.F. | Stabilized agar product and method for its stabilization |
LU73094A1 (en) * | 1975-07-29 | 1977-03-24 | ||
JPS56115727A (en) * | 1980-02-19 | 1981-09-11 | Kuraray Co Ltd | Carrier for immobilizing physiologically active substance |
DE3172131D1 (en) * | 1980-06-27 | 1985-10-10 | Akzo Nv | Porous inorganic support material coated with an organic stationary phase, for use in chromatography, and process for its preparation |
SE8302758L (en) | 1983-05-17 | 1984-11-18 | Pharmacia Ab | SET FOR DISTRIBUTION OF DISULPHIDE BINDINGS AND THEREFORE |
SE470261B (en) | 1984-05-17 | 1993-12-20 | Jerker Porath | Adsorbent for the separation and immobilization of proteins, methods of preparing an adsorbent, and its use for biopolymer fractionation |
SE470099B (en) | 1984-05-17 | 1993-11-08 | Jerker Porath | Sulfone activated thioether adsorbents for separation of eg protein |
US4544485A (en) | 1984-08-31 | 1985-10-01 | Purdue Research Foundation | Chromatographic method and means |
US4746572A (en) * | 1986-11-28 | 1988-05-24 | E. I. Dupont De Nemours And Company | Structures surface modified with bidentate silanes |
US4871711A (en) * | 1986-12-29 | 1989-10-03 | Aluminum Company Of America | Active material produced from metal oxide/hydroxide particles and phosphate esters |
EP0899567A1 (en) | 1989-07-06 | 1999-03-03 | Perseptive Biosystems, Inc. | Perfusive Chromatography |
DK164303C (en) | 1990-05-14 | 1992-10-19 | Vik Consult | INSULATION FOR A PIPE OR CHANNEL WITH A RELATIVE LOW SURFACE TEMPERATURE AND PROCEDURE FOR PREPARING THE INSULATION |
DK165090D0 (en) | 1990-07-09 | 1990-07-09 | Kem En Tec As | CONLOMERATED PARTICLES |
US5128291A (en) * | 1990-12-11 | 1992-07-07 | Wax Michael J | Porous titania or zirconia spheres |
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US5306561A (en) | 1992-02-20 | 1994-04-26 | Cornell Research Foundation, Inc. | Preparation of surface-functional polymer particles |
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US5906734A (en) * | 1992-06-19 | 1999-05-25 | Biosepra Inc. | Passivated porous polymer supports and methods for the preparation and use of same |
US5316680A (en) | 1992-10-21 | 1994-05-31 | Cornell Research Foundation, Inc. | Multimodal chromatographic separation media and process for using same |
US5653875A (en) * | 1994-02-04 | 1997-08-05 | Supelco, Inc. | Nucleophilic bodies bonded to siloxane and use thereof for separations from sample matrices |
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US5522994A (en) | 1995-02-01 | 1996-06-04 | Cornell Research Foundation, Inc. | Single column chromatographic determination of small molecules in mixtures with large molecules |
SE9600590D0 (en) | 1996-02-19 | 1996-02-19 | Pharmacia Biotech Ab | Methods for chromatographic separation of peptides and nucleic acid and new high-affinity ion exchange matrix |
SE9700768D0 (en) | 1997-03-04 | 1997-03-04 | Pharmacia Biotech Ab | Procedure for introducing functionality |
-
1997
- 1997-03-04 SE SE9700769A patent/SE9700769D0/en unknown
-
1998
- 1998-03-04 ES ES98908407T patent/ES2251766T3/en not_active Expired - Lifetime
- 1998-03-04 US US09/380,050 patent/US6572766B1/en not_active Expired - Lifetime
- 1998-03-04 JP JP53844798A patent/JP4135812B2/en not_active Expired - Lifetime
- 1998-03-04 AU AU66442/98A patent/AU729313B2/en not_active Expired
- 1998-03-04 DE DE69832166T patent/DE69832166T2/en not_active Revoked
- 1998-03-04 EP EP98908407A patent/EP0980288B1/en not_active Revoked
- 1998-03-04 WO PCT/SE1998/000387 patent/WO1998039094A1/en active IP Right Grant
- 1998-03-04 AT AT98908407T patent/ATE308380T1/en not_active IP Right Cessation
- 1998-03-04 CA CA002281846A patent/CA2281846C/en not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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US4535010A (en) * | 1982-10-18 | 1985-08-13 | Pharmacia Ab | Method of forming polymeric layers |
EP0221046A2 (en) * | 1985-11-01 | 1987-05-06 | Monsanto Company | Modified polymeric surfaces and process for preparing same |
US5030352A (en) * | 1990-01-25 | 1991-07-09 | Purdue Research Foundation | Coated media for chromatography |
WO1994009063A1 (en) * | 1992-10-21 | 1994-04-28 | Cornell Research Foundation, Inc. | Pore-size selective modification of porous materials |
Cited By (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6602990B1 (en) * | 1996-04-11 | 2003-08-05 | Amersham Biosciences Ab | Process for the production of a porous cross-linked polysaccharide gel and its use as a gel filtration media and in chromatography |
WO2001037987A1 (en) * | 1999-11-25 | 2001-05-31 | Amersham Biosciences Ab | A method for selective removal of a substance from samples containing compounds having nucleic acid structure |
US7347976B2 (en) | 2001-12-20 | 2008-03-25 | 3M Innovative Properties Company | Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix |
US7871827B2 (en) | 2001-12-20 | 2011-01-18 | 3M Innovative Properties Company | Methods and devices for removal of organic molecules from biological mixtures using anion exchange |
WO2004011141A1 (en) * | 2002-07-26 | 2004-02-05 | Applera Corporation | Size-exclusion ion-exchange particles |
WO2004011142A1 (en) * | 2002-07-26 | 2004-02-05 | Applera Corporation | Device and method for purification of nucleic acids |
JP2005533646A (en) * | 2002-07-26 | 2005-11-10 | アプレラ コーポレイション | Size exclusion ion exchange particles |
WO2004020994A1 (en) * | 2002-08-27 | 2004-03-11 | Amersham Biosciences Ab | Chromatographic two-layer particles |
US7208093B2 (en) * | 2002-08-27 | 2007-04-24 | Ge Healthcare Bio-Sciences Ab | Chromatographic two-layer particles |
CN100406114C (en) * | 2002-08-27 | 2008-07-30 | 通用电气健康护理生物科学股份公司 | Berg Hans,Busson Philippe,Carlsson Mats |
US7981600B2 (en) * | 2003-04-17 | 2011-07-19 | 3M Innovative Properties Company | Methods and devices for removal of organic molecules from biological mixtures using an anion exchange material that includes a polyoxyalkylene |
US7939249B2 (en) | 2003-12-24 | 2011-05-10 | 3M Innovative Properties Company | Methods for nucleic acid isolation and kits using a microfluidic device and concentration step |
EP1715953A1 (en) * | 2004-02-18 | 2006-11-02 | Applera Corporation | Polyelectrolyte-coated size-exclusion ion-exchange particles |
EP2277987A3 (en) * | 2004-02-18 | 2011-10-12 | Life Technologies Corporation | Polyelectrolyte-coated size-exclusion ion-exchange particles |
US20110045574A1 (en) * | 2008-04-22 | 2011-02-24 | Jan Bergstrom | Chromatography medium |
US10493380B2 (en) | 2008-04-22 | 2019-12-03 | Ge Healthcare Bioprocess R&D Ab | Chromatography medium |
US11439926B2 (en) | 2008-04-22 | 2022-09-13 | Cytiva Bioprocess R&D Ab | Chromatography medium |
WO2010027696A1 (en) * | 2008-08-25 | 2010-03-11 | Ge Healthcare Bio-Sciences Corp. | Simple load and elute process for purification of genomic dna |
Also Published As
Publication number | Publication date |
---|---|
EP0980288B1 (en) | 2005-11-02 |
US6572766B1 (en) | 2003-06-03 |
ATE308380T1 (en) | 2005-11-15 |
AU6644298A (en) | 1998-09-22 |
CA2281846C (en) | 2007-07-03 |
DE69832166D1 (en) | 2005-12-08 |
JP4135812B2 (en) | 2008-08-20 |
JP2001514745A (en) | 2001-09-11 |
EP0980288A1 (en) | 2000-02-23 |
DE69832166T2 (en) | 2006-08-03 |
ES2251766T3 (en) | 2006-05-01 |
SE9700769D0 (en) | 1997-03-04 |
CA2281846A1 (en) | 1998-09-11 |
AU729313B2 (en) | 2001-02-01 |
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