WO1998048706A1 - Occlusion device - Google Patents
Occlusion device Download PDFInfo
- Publication number
- WO1998048706A1 WO1998048706A1 PCT/GB1998/000652 GB9800652W WO9848706A1 WO 1998048706 A1 WO1998048706 A1 WO 1998048706A1 GB 9800652 W GB9800652 W GB 9800652W WO 9848706 A1 WO9848706 A1 WO 9848706A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- obturator
- stent
- tube
- tubule
- blocking element
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
- A61B17/12172—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12104—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in an air passage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12136—Balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12159—Solid plugs; being solid before insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12168—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
- A61B17/12177—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2002/043—Bronchi
Definitions
- the present invention relates to a device useful in the treatment of emphysema and other diseases or disorders of the human or animal lung.
- Emphysema is a disease of the lung caused primarily by prolonged smoking, although not exclusively thereby. It is an unrelentless, intractable and debilitating process. Emphysema is defined as an abnormal permanent enlargement of the air spaces distal to the terminal bronchioles, accompanied by destruction of their walls without obvious fibrosis. In this context, destruction means non- uniformity in the pattern of respiratory airspace enlargement; orderly appearance of the acinus is disturbed and may be lost.
- Emphysema causes a physiological loss of lung elastic recoil, which decreases expiratory airflow by loss of driving pressure and premature airway closure from reduced airway traction.
- the effect of this is that the alveoli become hyper-inflated without there being any real exchange of air with the outside. Therefore the patient begins to feel starved of oxygen and so attempts to breathe more deeply. In breathing more deeply, the effects are exacerbated.
- the major therapeutic modalities currently available consist of bronchodilator and anti-inflammatory drugs, directed at decreasing airway resistance, and antibiotics to treat acute and chronic infection.
- Supplemental oxygen therapy for the hypoxaemic patient improves exercise performance and improves survival in patients with cor pulmonale.
- the course of the disease is one of progressive limitation, increasing dyspnoea and significant increase in overall mortality.
- Emphysema is a distressing condition affecting a relatively large proportion of the population, and a more effective and less traumatic treatment is required.
- a method of treatment of emphysema or other lung conditions or diseases comprising placing an obturator in a bronchial tube or tubule so as to seal the tube or tubule against the passage of fluid past the obturator.
- a section of a lung can be isolated so that no air can be drawn into it. Thereafter, the isolated part deflates in time as the air remaining in it becomes absorbed, and so that part of the lung stops affecting other areas of the lungs, which can thus perform normally.
- Such a procedure is relatively simple, requiring only a delivery device for the obturator, which device is inserted through the mouth and airway of the patient until the proposed placement site is reached, whereupon the device is activated to release the obturator from the device.
- an obturator stops the flow of blood.
- the lung is tamponated by the obturator and blood merely collects in the isolated part of the lung and ultimately, if the bleeding stops, will be reabsorbed.
- some, perhaps terminal, conditions such as some lung cancers, it at least provides temporary relief for the patient.
- an obturator for a bronchial tube or tubule of a human or animal lung comprising a blocking element and a securing element.
- the two elements are separate components, the blocking element serving to seal the tube or tubule against the passage of fluid past the obturator when the obturator is disposed in a bronchial tube or tubule, and the securing element serving to retain the blocking element in position in the tube or tubule.
- the blocking element preferably comprises a substantially cylindrical plug of biocompatible material.
- the plug may comprise resiliently deformable closed-cell foamed plastics material, such as PVC, so that it may be compressed to facilitate insertion into the tube or tubule and thereafter expand to fill the cross-section of the tube or tubule.
- a stent is a compressible framework which, when inserted into a vessel and released, expands and, within the limits of its expansion, supports and possibly expands the walls of the vessel.
- the securing element comprises a stent.
- the stent may have barbs to engage and retain the blocking element.
- the stent preferably also has anchors to retain the stent in a bronchial tube or tubule.
- the stent comprises a crown of surgical quality steel wire legs in zig-zag formation. Said barbs and anchors may depend from points of the crown. Preferably the crown is closed in its circumference, although this is not essential.
- the stent comprises a dome of surgical quality steel wire legs. Said barbs and anchors may be formed on the ends of said legs.
- a complete seal is an absolute requirement of the present invention (at least over the period of a single breath), because without it, air can leak past during inhalation and pressurise the lung in just the same way, and perhaps even to a greater extent. More importantly, however, a patient with such an obturator in place can only feel its presence if there is movement of air around it to stimulate adjacent nerve endings. Once a patient can feel the obturator, there will be irresistible compulsion to cough which, if done excessively, may be sufficient to dislodge the obturator.
- the method of the present invention employs an obturator of the type defined above.
- the delivery device preferably comprises a delivery tube in which the obturator is received in a compressed state at a distal end thereof, a guide tube, which is capable of following a possibly tortuous path under the guidance of a surgeon from entry into the mouth of a patient, down the patient ' s trachea and one bronchus to a proposed delivery site in a bronchial tube or tubule, and which has a passage to receive the delivery tube therealong, and release means to eject the obturator from the delivery tube and guide tube.
- the obturator needs to slide in the delivery tube during ejection and the stent provides a low friction surface of the obturator to facilitate such ejection.
- the blocking and securing elements may be integrally formed from plastics material, and wherein the securing element comprises adhered or fused anchor elements on the blocking element. It is also feasible that the securing element may comprise a memory metal which is released to its normal expanded shape by a physical parameter, for example, the passage of an electric current therethrough, once it has been inserted at the proposed location. Otherwise it is in the same form as the above described steel stent which relies on resilience for its expansion.
- the advantage of a memory metal device is that it requires no compression during insertion so that the delivery tube of the delivery device may be replaced by a simple guide rod to which it is connected.
- Figure 1 shows a section through the human chest indicating the location of bronchial obturators in the lungs
- Figure 2 shows a bronchial obturator complete with delivery system
- Figures 3a b and c show in perspective two embodiments of an obturator according to the present invention, that of Figure 3a having a crown stent, and that of Figure 3b having a dome stent, Figure 3c being a crown stent in an open configuration prior to rolling and, optionally, welding into a ring as in Figure 3a;
- Figures 4a and b show an internal barb and external anchor respectively;
- Figure 5 is a perspective view of another embodiment of obturator in accordance with the present invention.
- Figure 6 is a perspective view of yet another embodiment of obturator also in accordance with the present invention.
- a human chest cavity 10 includes a pair of lungs 12 which each comprise upper and lower lobes 14,16.
- a trachea 18 branches into two bronchi 20, which further branch into bronchial tubes 22 and segmental bronchi 24.
- the present invention suggests placing an obturator 50 in a bronchial tube or tubule to isolate the region of the lung supplied by that tube or tubule.
- the obturator is placed will be decided by the surgeon and will depend on the how localised the damaged region of lung is. That is to say, if the whole lobe is badly affected, then the obturator is placed in the lobar bronchus 22 supplying that lobe ( as shown at 50 in Figure 1). On the other hand, if the damage is more localised, then the obturator will be placed in a smaller segmental bronchus 24, (as shown at 50' in Figure 1). Thus more than one obturator may be employed in the same pair of lungs isolating different regions of them. They will also be of different sizes, depending where they are to be inserted.
- condition being treated is not emphysema but some other condition which a doctor considers can usefully be treated by the method of the present invention.
- Such another condition is where a lung, or part of it is bleeding into the airway and an obturator isolates the bleeding region and inhibits coughing which may damage the lung further, or at least cause further discomfort to the patient.
- FIG. 2 shows an endo-bronchial obturator 50 complete with delivery device 70.
- the delivery device comprises a handle 72 and flexible guide tube 74. Slidably received in the guide tube is a delivery tube 76 having the obturator 50 disposed at its distal end 78.
- a release means 80 is insertable in a proximal end 82 of the delivery tube 82 and by means of which the obturator 50 may be ejected from the end of the delivery tube.
- the guide tube is guided down the trachea and into the appropriate bronchus by means of guide lines (not shown) which enable the delivery system to be turned to follow the desired course.
- Optical guidance means may be included, or real-time X-ray or other monitoring methods may be employed to guide the surgeon.
- the delivery tube is inserted in the handle end of the delivery device 70, and then the release means 80 is pushed down the tube 82 to eject the obturator.
- the obturator is adapted to expand or be expanded, when ejected, to fill and block the tube or tubule in which it is inserted.
- the obturator 50 in its first embodiment is comprised of two main components, a securing element in the form of a stent 90, and a blocking element in the form of a closed-cell, PVC foam plug 92.
- the stent 90 is constructed from a plurality of legs 91 of surgical grade stainless steel wire welded together such that when extended the stent appears as a series of connected 'W's, as shown in an unconnected disposition in Figure 3c. Indeed, it is not essential that the final connection between ends 94,96 be made to form a closed crown arrangement (as shown in Figure 3a); it is equally effective merely to roll the stent 90b as indicated by arrows in Figure 3c.
- the stent 90 folds into a circular frame or crown, capable of encompassing the biocompatible block 92.
- the stent is constructed so as to be of a size slightly smaller ( in its unstressed condition) than the block, so that its natural resilience squeezes the block slightly.
- the stent should be larger than the airway into which it is to be introduced so that it presses outwardly against the wall of the airway, and is incorporated into the mucosa of the air passage.
- FIG. 4a shows an internal barb 98.
- the internal barb also constructed from surgical quality stainless steel, is substantially straight and has a hook 99 at one end. The hooked end 99 is the point and means by which the barb is secured to the biocompatible block.
- Figure 4b shows an external anchor 100.
- the anchor which is also constructed from surgical quality stainless steel, is again substantially straight and has a coil 101 at its end.
- a coil is used so that damage is not caused to the tissue of the airway in which the obturator is fitted, particularly if and when the obturator is removed.
- barbs and anchors are joined to the stent crown by a welded joint between two adjacent legs 91.
- Barbs can alternate with anchors at the same end of the stent, or one end can have all barbs, while the other end has all anchors. Both arrangements are shown in Figures 3a and c respectively.
- FIG. 3b A different embodiment of obturator 50b, also in accordance with the present invention, is shown in Figure 3b in which surgical quality stainless steel wires are all welded together at a point 104 to form a domed stent 90b. Legs 91b are alternately turned inwards to form barbs 98b, or outwards to form anchors 100b. Alternatively, all the legs could be anchors 100b, with interspersed shorter barbs 98bb, as one is shown in dashed lines in Figure 3b.
- the aforementioned obturators all rely on resilience of the steel to return the stent to its original shape once released from the delivery mechanism and so as to enable fitment in a narrower tubule than the unstressed size of the stent would otherwise allow. However, this requires prestressing the stent and keeping it stressed during delivery. Thus the present invention may find suitable application for memory metals, which only return to their original shape when some physical condition changes, for example, temperature rise or electrical current flow.
- the blocking device 50 is essential for the blocking device 50 to be comprised of a resiliently deformable material such as PVC foam as mentioned above. This enables the blocking device to be easily surrounded by the stent 90 and deformed into a compact structure, thereby enabling delivery of the block to its destination in the lung.
- a resiliently deformable material such as PVC foam
- the block be capable of expanding and reforming into its original shape once deposited in the desired location in the lungs. It should be noted that the block is deformed and reformed in both an axial and a radial direction. It is the block 92 which seals a bronchial tube or tubule; mucous surrounds the block and forms a fluid tight seal . The presence of the stent around the block does not inhibit sealing in any way since the stent is essentially incorporated into the mucosa lining the airway.
- PVC foam Under compression, PVC foam has a high coefficient of friction which would prevent ejection from the delivery device as described above, if it was not surrounded by the stent 90, which offers a relatively low friction surface to the inside of delivery tube 76.
- the block 92 could include a low friction surface to enable such ejection without the stent.
- anchor means might be moulded in biocompatible plastics material as a crown, for example, on one end of the block, and either be adhered, fused or otherwise bound thereto.
- the effectiveness of the device depends, to some extent, on the length of the block.
- the block is required to be of a size which is both comfortable to the patient once expanded in the lung and which expands to completely obstruct the passage of air into the affected portions of the lung.
- the extended size of the block therefore ranges between 5mm and 25mm in length, and between 5 and 11mm in diameter, depending on the size of the tube or tubule to be obturated.
- Obturator 50c shown in Figure 5 comprises a balloon 200, which is inflated after insertion and then detached.
- the balloon is captivated in an appropriate securing device such as stent 202.
- the barbs would not be sharp, but would merely retain ends of the balloon, or, as shown, would comprises turned-in points 204,206 at each end of the stent.
- the obturator may be as shown at 50d in Figure 6, where it comprises a diaphragm 300 expanded by an internal stent 302 having anchors 302. One end 306 of the diaphragm is attached to the stent to retain it on the stent. The diaphragm is also adhered to the stent.
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/762,692 US7670373B1 (en) | 1997-04-30 | 1998-03-03 | Occlusion device |
AU66301/98A AU6630198A (en) | 1997-04-30 | 1998-03-03 | Occlusion device |
US11/515,181 US20070005083A1 (en) | 1997-04-30 | 2006-09-01 | Occlusion device |
US12/687,805 US8136520B2 (en) | 1997-04-30 | 2010-01-14 | Occlusion device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9708681.3 | 1997-04-30 | ||
GB9708681A GB2324729B (en) | 1997-04-30 | 1997-04-30 | Lung treatment device |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/762,692 A-371-Of-International US7670373B1 (en) | 1997-04-30 | 1998-03-03 | Occlusion device |
US11/515,181 Continuation US20070005083A1 (en) | 1997-04-30 | 2006-09-01 | Occlusion device |
US12/687,805 Continuation US8136520B2 (en) | 1997-04-30 | 2010-01-14 | Occlusion device |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998048706A1 true WO1998048706A1 (en) | 1998-11-05 |
Family
ID=10811536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1998/000652 WO1998048706A1 (en) | 1997-04-30 | 1998-03-03 | Occlusion device |
Country Status (6)
Country | Link |
---|---|
US (3) | US7670373B1 (en) |
EP (1) | EP1157663A1 (en) |
AU (1) | AU6630198A (en) |
GB (1) | GB2324729B (en) |
HK (1) | HK1043030A1 (en) |
WO (1) | WO1998048706A1 (en) |
Cited By (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001002042A1 (en) | 1999-07-02 | 2001-01-11 | Pulmonx | Methods, systems, and kits for lung volume reduction |
US6258100B1 (en) | 1999-08-24 | 2001-07-10 | Spiration, Inc. | Method of reducing lung size |
WO2001087170A1 (en) * | 2000-05-18 | 2001-11-22 | Emphasys Medical, Inc. | Bronchiopulmonary occlusion devices and lung volume reduction methods |
US6410536B1 (en) | 1998-03-31 | 2002-06-25 | Warner-Lambert Company | Quinoxalinones as serine protease inhibitors such as factor XA and thrombin |
US6514290B1 (en) | 2000-03-31 | 2003-02-04 | Broncus Technologies, Inc. | Lung elastic recoil restoring or tissue compressing device and method |
WO2002022072A3 (en) * | 2000-09-11 | 2003-08-14 | Closure Medical Corp | Bronchial occlusion method and apparatus |
WO2003088820A2 (en) * | 2002-04-19 | 2003-10-30 | Broncus Technologies, Inc. | Devices for maintaining surgically created openings |
US6679264B1 (en) * | 2000-03-04 | 2004-01-20 | Emphasys Medical, Inc. | Methods and devices for use in performing pulmonary procedures |
EP1494657A2 (en) * | 2002-04-16 | 2005-01-12 | Spiration, Inc. | Removable anchored lung volume reduction devices and methods |
US6997918B2 (en) | 2000-10-27 | 2006-02-14 | Pulmonx | Methods and devices for obstructing and aspirating lung tissue segments |
WO2006055692A2 (en) | 2004-11-16 | 2006-05-26 | Pulmonx | Pulmonary occlusal stent delivery catheter, loading system and methods of use |
WO2006055683A2 (en) | 2004-11-16 | 2006-05-26 | Pulmonx | Occlusal stent and methods for its use |
US7144392B2 (en) | 2001-07-19 | 2006-12-05 | Olympus Corporation | Medical embolization element and method of embolizing tubular organ |
US7357795B2 (en) | 2001-07-19 | 2008-04-15 | Olympus Corporation | Medical device and method of embolizing bronchus or bronchiole |
AU2005202552B2 (en) * | 1999-08-05 | 2008-07-03 | Broncus Technologies, Inc. | Methods and devices for creating collateral channels in the lungs |
JP2009297548A (en) * | 2009-09-28 | 2009-12-24 | Olympus Corp | Medical obturator |
US7691151B2 (en) | 2006-03-31 | 2010-04-06 | Spiration, Inc. | Articulable Anchor |
US7896887B2 (en) | 2001-10-25 | 2011-03-01 | Spiration, Inc. | Apparatus and method for deployment of a bronchial obstruction device |
US8100959B2 (en) | 2007-03-09 | 2012-01-24 | Pulmonx Corporation | Loading device for a pulmonary implant |
US8136520B2 (en) | 1997-04-30 | 2012-03-20 | Pulmonx Corporation | Occlusion device |
JP2012130726A (en) * | 2012-02-20 | 2012-07-12 | Olympus Corp | Obturator for medical treatment |
US8251067B2 (en) | 2001-03-02 | 2012-08-28 | Pulmonx Corporation | Bronchial flow control devices with membrane seal |
US8388682B2 (en) | 2004-11-19 | 2013-03-05 | Pulmonx Corporation | Bronchial flow control devices and methods of use |
US8474460B2 (en) | 2000-03-04 | 2013-07-02 | Pulmonx Corporation | Implanted bronchial isolation devices and methods |
US8852229B2 (en) | 2003-10-17 | 2014-10-07 | Cordis Corporation | Locator and closure device and method of use |
US8888812B2 (en) | 2000-12-14 | 2014-11-18 | Cordis Corporation | Plug with collet and apparatus and methods for delivering such plugs |
US8926647B2 (en) | 2002-03-20 | 2015-01-06 | Spiration, Inc. | Removable anchored lung volume reduction devices and methods |
US8926654B2 (en) | 2005-05-04 | 2015-01-06 | Cordis Corporation | Locator and closure device and method of use |
US8932316B2 (en) | 2011-05-13 | 2015-01-13 | Broncus Medical Inc. | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
US8956319B2 (en) | 2002-05-17 | 2015-02-17 | Spiration, Inc. | One-way valve devices for anchored implantation in a lung |
US8974527B2 (en) | 2003-08-08 | 2015-03-10 | Spiration, Inc. | Bronchoscopic repair of air leaks in a lung |
US8974484B2 (en) | 2001-09-11 | 2015-03-10 | Spiration, Inc. | Removable lung reduction devices, systems, and methods |
US9050094B2 (en) | 2007-03-12 | 2015-06-09 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
US9211181B2 (en) | 2004-11-19 | 2015-12-15 | Pulmonx Corporation | Implant loading device and system |
USRE45921E1 (en) | 2000-03-23 | 2016-03-15 | Spiration, Inc. | Tissue resection device, system, and method |
US9326873B2 (en) | 2007-10-12 | 2016-05-03 | Spiration, Inc. | Valve loader method, system, and apparatus |
US9345532B2 (en) | 2011-05-13 | 2016-05-24 | Broncus Medical Inc. | Methods and devices for ablation of tissue |
US9492148B2 (en) | 2000-12-14 | 2016-11-15 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Apparatus and methods for sealing vascular punctures |
US9533116B2 (en) | 2005-01-20 | 2017-01-03 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
US9533128B2 (en) | 2003-07-18 | 2017-01-03 | Broncus Medical Inc. | Devices for maintaining patency of surgically created channels in tissue |
US9655602B2 (en) | 2000-12-14 | 2017-05-23 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Vascular plug having composite construction |
US9913969B2 (en) | 2006-10-05 | 2018-03-13 | Broncus Medical Inc. | Devices for delivering substances through an extra-anatomic opening created in an airway |
US10272260B2 (en) | 2011-11-23 | 2019-04-30 | Broncus Medical Inc. | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
US10413244B2 (en) | 2001-09-10 | 2019-09-17 | Pulmonx Corporation | Method and apparatus for endobronchial diagnosis |
JP7333030B2 (en) | 2019-09-24 | 2023-08-24 | 国立大学法人 長崎大学 | fistula treatment instrument |
US11883029B2 (en) | 2005-01-20 | 2024-01-30 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5954766A (en) | 1997-09-16 | 1999-09-21 | Zadno-Azizi; Gholam-Reza | Body fluid flow control device |
AUPP624398A0 (en) * | 1998-09-29 | 1998-10-22 | White, Geoffrey H. | Expanding intraluminal device |
AU2004200295B2 (en) * | 1998-09-29 | 2006-08-17 | W. L. Gore & Associates, Inc. | Expanding intraluminal device |
DE29911766U1 (en) * | 1999-07-09 | 1999-12-30 | Schedler Michael | Device for collecting blood during operations in the area of the upper respiratory tract and / or the nasopharynx |
AU2001267097A1 (en) | 2000-06-16 | 2001-12-24 | Rajiv Doshi | Methods and devices for improving breathing in patients with pulmonary disease |
US6941950B2 (en) * | 2001-10-11 | 2005-09-13 | Emphasys Medical, Inc. | Bronchial flow control devices and methods of use |
US7798147B2 (en) | 2001-03-02 | 2010-09-21 | Pulmonx Corporation | Bronchial flow control devices with membrane seal |
US6929637B2 (en) | 2002-02-21 | 2005-08-16 | Spiration, Inc. | Device and method for intra-bronchial provision of a therapeutic agent |
EP1494632B1 (en) * | 2002-03-20 | 2019-04-17 | Spiration, Inc. | Removable anchored lung volume reduction devices |
FR2840796B1 (en) * | 2002-06-13 | 2004-09-10 | Novatech Inc | BRONCHICAL SHUTTER |
US20100158795A1 (en) * | 2008-06-12 | 2010-06-24 | Pulmonx | Methods and systems for assessing lung function and delivering therapeutic agents |
US7814912B2 (en) | 2002-11-27 | 2010-10-19 | Pulmonx Corporation | Delivery methods and devices for implantable bronchial isolation devices |
US7100616B2 (en) | 2003-04-08 | 2006-09-05 | Spiration, Inc. | Bronchoscopic lung volume reduction method |
US7811274B2 (en) * | 2003-05-07 | 2010-10-12 | Portaero, Inc. | Method for treating chronic obstructive pulmonary disease |
US7426929B2 (en) | 2003-05-20 | 2008-09-23 | Portaero, Inc. | Intra/extra-thoracic collateral ventilation bypass system and method |
US7533667B2 (en) * | 2003-05-29 | 2009-05-19 | Portaero, Inc. | Methods and devices to assist pulmonary decompression |
US7252086B2 (en) * | 2003-06-03 | 2007-08-07 | Cordis Corporation | Lung reduction system |
US7377278B2 (en) | 2003-06-05 | 2008-05-27 | Portaero, Inc. | Intra-thoracic collateral ventilation bypass system and method |
US7682332B2 (en) * | 2003-07-15 | 2010-03-23 | Portaero, Inc. | Methods to accelerate wound healing in thoracic anastomosis applications |
US8206684B2 (en) | 2004-02-27 | 2012-06-26 | Pulmonx Corporation | Methods and devices for blocking flow through collateral pathways in the lung |
WO2005122870A2 (en) | 2004-06-14 | 2005-12-29 | Pneumrx, Inc. | Lung access device |
US7549984B2 (en) * | 2004-06-16 | 2009-06-23 | Pneumrx, Inc. | Method of compressing a portion of a lung |
US7766891B2 (en) | 2004-07-08 | 2010-08-03 | Pneumrx, Inc. | Lung device with sealing features |
WO2006014567A2 (en) | 2004-07-08 | 2006-02-09 | Pneumrx, Inc. | Pleural effusion treatment device, method and material |
US20060118126A1 (en) * | 2004-11-19 | 2006-06-08 | Don Tanaka | Methods and devices for controlling collateral ventilation |
US8220460B2 (en) * | 2004-11-19 | 2012-07-17 | Portaero, Inc. | Evacuation device and method for creating a localized pleurodesis |
US7398782B2 (en) * | 2004-11-19 | 2008-07-15 | Portaero, Inc. | Method for pulmonary drug delivery |
US9125639B2 (en) | 2004-11-23 | 2015-09-08 | Pneumrx, Inc. | Steerable device for accessing a target site and methods |
US7735491B2 (en) | 2004-12-08 | 2010-06-15 | Ventus Medical, Inc. | Methods of treating respiratory disorders |
US9833354B2 (en) | 2004-12-08 | 2017-12-05 | Theravent, Inc. | Nasal respiratory devices |
US10610228B2 (en) | 2004-12-08 | 2020-04-07 | Theravent, Inc. | Passive nasal peep devices |
US7824366B2 (en) * | 2004-12-10 | 2010-11-02 | Portaero, Inc. | Collateral ventilation device with chest tube/evacuation features and method |
US8876791B2 (en) | 2005-02-25 | 2014-11-04 | Pulmonx Corporation | Collateral pathway treatment using agent entrained by aspiration flow current |
US8104474B2 (en) * | 2005-08-23 | 2012-01-31 | Portaero, Inc. | Collateral ventilation bypass system with retention features |
US7406963B2 (en) * | 2006-01-17 | 2008-08-05 | Portaero, Inc. | Variable resistance pulmonary ventilation bypass valve and method |
US8136526B2 (en) | 2006-03-08 | 2012-03-20 | Pulmonx Corporation | Methods and devices to induce controlled atelectasis and hypoxic pulmonary vasoconstriction |
US9402633B2 (en) | 2006-03-13 | 2016-08-02 | Pneumrx, Inc. | Torque alleviating intra-airway lung volume reduction compressive implant structures |
US8157837B2 (en) | 2006-03-13 | 2012-04-17 | Pneumrx, Inc. | Minimally invasive lung volume reduction device and method |
US8888800B2 (en) | 2006-03-13 | 2014-11-18 | Pneumrx, Inc. | Lung volume reduction devices, methods, and systems |
EP2015681B1 (en) | 2006-05-03 | 2018-03-28 | Datascope Corp. | Tissue closure device |
GB0610171D0 (en) | 2006-05-23 | 2006-06-28 | Robitaille Jean Pierre | Valved nasal canula |
CA2653139C (en) | 2006-05-23 | 2016-01-05 | Ventus Medical, Inc. | Nasal respiratory devices |
EP2032213A4 (en) | 2006-06-07 | 2014-02-19 | Theravent Inc | Nasal devices |
CN101489630B (en) | 2006-06-07 | 2013-10-23 | 温吐斯医学公司 | Layered nasal devices |
US20080051830A1 (en) * | 2006-08-24 | 2008-02-28 | Boston Scientific Scimed, Inc. | Occluding device and method |
US20080072914A1 (en) * | 2006-08-25 | 2008-03-27 | Hendricksen Michael J | Bronchial Isolation Devices for Placement in Short Lumens |
US8342182B2 (en) | 2006-08-28 | 2013-01-01 | Pulmonx Corporation | Functional assessment and treatment catheters and methods for their use in the lung |
WO2008061250A2 (en) | 2006-11-16 | 2008-05-22 | Ventus Medical, Inc. | Adjustable nasal devices |
US20080221582A1 (en) * | 2007-03-05 | 2008-09-11 | Pulmonx | Pulmonary stent removal device |
US7931641B2 (en) | 2007-05-11 | 2011-04-26 | Portaero, Inc. | Visceral pleura ring connector |
US8163034B2 (en) * | 2007-05-11 | 2012-04-24 | Portaero, Inc. | Methods and devices to create a chemically and/or mechanically localized pleurodesis |
US20080281151A1 (en) * | 2007-05-11 | 2008-11-13 | Portaero, Inc. | Pulmonary pleural stabilizer |
US20080283065A1 (en) * | 2007-05-15 | 2008-11-20 | Portaero, Inc. | Methods and devices to maintain patency of a lumen in parenchymal tissue of the lung |
US8062315B2 (en) | 2007-05-17 | 2011-11-22 | Portaero, Inc. | Variable parietal/visceral pleural coupling |
US20080295829A1 (en) * | 2007-05-30 | 2008-12-04 | Portaero, Inc. | Bridge element for lung implant |
US8043301B2 (en) | 2007-10-12 | 2011-10-25 | Spiration, Inc. | Valve loader method, system, and apparatus |
US8020700B2 (en) | 2007-12-05 | 2011-09-20 | Ventus Medical, Inc. | Packaging and dispensing nasal devices |
WO2009105432A2 (en) * | 2008-02-19 | 2009-08-27 | Portaero, Inc. | Devices and methods for delivery of a therapeutic agent through a pneumostoma |
US8475389B2 (en) * | 2008-02-19 | 2013-07-02 | Portaero, Inc. | Methods and devices for assessment of pneumostoma function |
US8336540B2 (en) * | 2008-02-19 | 2012-12-25 | Portaero, Inc. | Pneumostoma management device and method for treatment of chronic obstructive pulmonary disease |
WO2009117012A1 (en) | 2008-03-17 | 2009-09-24 | Ventus Medical, Inc. | Adhesive nasal respiratory devices |
US8632605B2 (en) | 2008-09-12 | 2014-01-21 | Pneumrx, Inc. | Elongated lung volume reduction devices, methods, and systems |
US8986338B2 (en) | 2008-10-29 | 2015-03-24 | Cook Biotech Incorporated | Vascular plugs |
US8347881B2 (en) * | 2009-01-08 | 2013-01-08 | Portaero, Inc. | Pneumostoma management device with integrated patency sensor and method |
US8518053B2 (en) * | 2009-02-11 | 2013-08-27 | Portaero, Inc. | Surgical instruments for creating a pneumostoma and treating chronic obstructive pulmonary disease |
EP2432422A4 (en) | 2009-05-18 | 2018-01-17 | PneumRx, Inc. | Cross-sectional modification during deployment of an elongate lung volume reduction device |
US8875711B2 (en) | 2010-05-27 | 2014-11-04 | Theravent, Inc. | Layered nasal respiratory devices |
US9592008B2 (en) | 2010-07-01 | 2017-03-14 | Pulmonx Corporation | Devices and systems for lung treatment |
US8795241B2 (en) | 2011-05-13 | 2014-08-05 | Spiration, Inc. | Deployment catheter |
EP2760390B1 (en) | 2011-09-29 | 2019-06-12 | Trudell Medical International | Nasal insert |
GB2513068B (en) | 2012-01-17 | 2018-12-19 | Spiration Inc | Devices for treating fistulas in the lung and trachea |
US10058332B2 (en) * | 2012-08-01 | 2018-08-28 | Terumo Kabushiki Kaisha | Method for treatment of chronic obstructive pulmonary disease |
WO2015077356A1 (en) | 2013-11-19 | 2015-05-28 | Wheeler William K | Fastener applicator with interlock |
CN104188733B (en) * | 2014-08-11 | 2016-07-06 | 中国人民解放军总医院 | For forming the device of blood vessel embolism, system and application thereof |
US10390838B1 (en) | 2014-08-20 | 2019-08-27 | Pneumrx, Inc. | Tuned strength chronic obstructive pulmonary disease treatment |
US9592138B1 (en) | 2015-09-13 | 2017-03-14 | Martin Mayse | Pulmonary airflow |
GB2563538B (en) * | 2016-03-30 | 2021-09-22 | Gyrus Acmi Inc | Airway Valve with anchor |
CN112074240A (en) | 2018-03-28 | 2020-12-11 | 数据显示器公司 | Auricle removing device |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0204218A1 (en) * | 1985-05-31 | 1986-12-10 | Stöckert Instrumente GmbH | Balloon catheter |
US4710192A (en) * | 1985-12-30 | 1987-12-01 | Liotta Domingo S | Diaphragm and method for occlusion of the descending thoracic aorta |
DE9205797U1 (en) * | 1992-04-30 | 1992-06-17 | Schmitz-Rode, Thomas, Dipl.-Ing. Dr.Med. | |
DE4101936A1 (en) * | 1991-01-21 | 1992-07-23 | Fischer Matthias | Intravascular perfusion throttling device - consists of balloon with radially extending ribs |
US5246445A (en) * | 1990-04-19 | 1993-09-21 | Instent Inc. | Device for the treatment of constricted ducts in human bodies |
WO1994026175A1 (en) * | 1993-05-06 | 1994-11-24 | Vitaphore Corporation | Embolization device |
US5382261A (en) * | 1992-09-01 | 1995-01-17 | Expandable Grafts Partnership | Method and apparatus for occluding vessels |
WO1995032018A1 (en) * | 1994-05-25 | 1995-11-30 | Teirstein Paul S | Body passageway closure apparatus and method |
Family Cites Families (98)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2832078A (en) | 1956-10-17 | 1958-04-29 | Battelle Memorial Institute | Heart valve |
US2981254A (en) | 1957-11-12 | 1961-04-25 | Edwin G Vanderbilt | Apparatus for the gas deflation of an animal's stomach |
US3320972A (en) | 1964-04-16 | 1967-05-23 | Roy F High | Prosthetic tricuspid valve and method of and device for fabricating same |
US3445916A (en) | 1967-04-19 | 1969-05-27 | Rudolf R Schulte | Method for making an anatomical check valve |
US3671979A (en) | 1969-09-23 | 1972-06-27 | Univ Utah | Catheter mounted artificial heart valve for implanting in close proximity to a defective natural heart valve |
US3657744A (en) | 1970-05-08 | 1972-04-25 | Univ Minnesota | Method for fixing prosthetic implants in a living body |
US3788327A (en) | 1971-03-30 | 1974-01-29 | H Donowitz | Surgical implant device |
US3874388A (en) | 1973-02-12 | 1975-04-01 | Ochsner Med Found Alton | Shunt defect closure system |
US4014318A (en) | 1973-08-20 | 1977-03-29 | Dockum James M | Circulatory assist device and system |
US4084268A (en) | 1976-04-22 | 1978-04-18 | Shiley Laboratories, Incorporated | Prosthetic tissue heart valve |
US4056854A (en) | 1976-09-28 | 1977-11-08 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Aortic heart valve catheter |
US4086665A (en) | 1976-12-16 | 1978-05-02 | Thermo Electron Corporation | Artificial blood conduit |
US4250873A (en) | 1977-04-26 | 1981-02-17 | Richard Wolf Gmbh | Endoscopes |
DK229077A (en) | 1977-05-25 | 1978-11-26 | Biocoating Aps | HEARTBALL PROSTHET AND PROCEDURE FOR MANUFACTURING IT |
US4212463A (en) | 1978-02-17 | 1980-07-15 | Pratt Enoch B | Humane bleeder arrow |
US4222126A (en) | 1978-12-14 | 1980-09-16 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare | Unitized three leaflet heart valve |
SU852321A1 (en) | 1979-10-02 | 1981-08-07 | Второй Московский Ордена Ленинагосударственный Медицинский Ин-Ститут Им. H.И.Пирогова | Method of treating acute purulent diseases of lungs and pleura of children |
DE3019996A1 (en) | 1980-05-24 | 1981-12-03 | Institute für Textil- und Faserforschung Stuttgart, 7410 Reutlingen | HOHLORGAN |
US4808183A (en) | 1980-06-03 | 1989-02-28 | University Of Iowa Research Foundation | Voice button prosthesis and method for installing same |
US4302854A (en) | 1980-06-04 | 1981-12-01 | Runge Thomas M | Electrically activated ferromagnetic/diamagnetic vascular shunt for left ventricular assist |
US4339831A (en) | 1981-03-27 | 1982-07-20 | Medtronic, Inc. | Dynamic annulus heart valve and reconstruction ring |
US4477930A (en) | 1982-09-28 | 1984-10-23 | Mitral Medical International, Inc. | Natural tissue heat valve and method of making same |
DE3583141D1 (en) | 1984-11-15 | 1991-07-11 | Stefano Nazari | DEVICE FOR SELECTIVE BRONCHIAL INTUBATION AND SEPARATE LUNG VENTILATION. |
ES8705239A1 (en) | 1984-12-05 | 1987-05-01 | Medinvent Sa | A device for implantation and a method of implantation in a vessel using such device. |
US4759758A (en) | 1984-12-07 | 1988-07-26 | Shlomo Gabbay | Prosthetic heart valve |
SU1371700A1 (en) | 1986-02-21 | 1988-02-07 | МВТУ им.Н.Э.Баумана | Prosthesis of heart valve |
US4832680A (en) | 1986-07-03 | 1989-05-23 | C.R. Bard, Inc. | Apparatus for hypodermically implanting a genitourinary prosthesis |
US4698294A (en) * | 1986-09-12 | 1987-10-06 | E. I. Du Pont De Nemours And Company | Lamination of photopolymerizable film onto a substrate employing an intermediate nonphotosensitive liquid layer |
SU1593651A1 (en) | 1987-07-07 | 1990-09-23 | 1-Й Московский Медицинский Институт Им.И.М.Сеченова | Artery prosthesis |
DE3821631A1 (en) | 1987-07-28 | 1989-02-09 | Bader Paul | CLOSURE FOR A MALE UTILITY |
US4774942A (en) | 1987-08-28 | 1988-10-04 | Litton Systems, Inc. | Balanced exhalation valve for use in a closed loop breathing system |
US4879998A (en) | 1987-08-28 | 1989-11-14 | Litton Systems, Inc. | Balanced exhalation valve for use in a closed loop breathing system |
US4830003A (en) | 1988-06-17 | 1989-05-16 | Wolff Rodney G | Compressive stent and delivery system |
JP2710355B2 (en) | 1988-09-20 | 1998-02-10 | 日本ゼオン株式会社 | Medical valve device |
SE8803444D0 (en) | 1988-09-28 | 1988-09-28 | Medinvent Sa | A DEVICE FOR TRANSLUMINAL IMPLANTATION OR EXTRACTION |
US4846836A (en) | 1988-10-03 | 1989-07-11 | Reich Jonathan D | Artificial lower gastrointestinal valve |
US4877025A (en) | 1988-10-06 | 1989-10-31 | Hanson Donald W | Tracheostomy tube valve apparatus |
DE3834545A1 (en) | 1988-10-11 | 1990-04-12 | Rau Guenter | FLEXIBLE LOCKING ORGAN, PARTICULARLY HEART VALVE, AND METHOD FOR PRODUCING THE SAME |
US4994069A (en) * | 1988-11-02 | 1991-02-19 | Target Therapeutics | Vaso-occlusion coil and method |
US4968294A (en) | 1989-02-09 | 1990-11-06 | Salama Fouad A | Urinary control valve and method of using same |
US4946463A (en) * | 1989-04-10 | 1990-08-07 | Pioneering Technologies, Inc. | Vessel occluder |
US5352240A (en) | 1989-05-31 | 1994-10-04 | Promedica International, Inc. | Human heart valve replacement with porcine pulmonary valve |
WO1990014804A1 (en) | 1989-05-31 | 1990-12-13 | Baxter International Inc. | Biological valvular prosthesis |
US5562608A (en) | 1989-08-28 | 1996-10-08 | Biopulmonics, Inc. | Apparatus for pulmonary delivery of drugs with simultaneous liquid lavage and ventilation |
US5061274A (en) | 1989-12-04 | 1991-10-29 | Kensey Nash Corporation | Plug device for sealing openings and method of use |
US4983177A (en) * | 1990-01-03 | 1991-01-08 | Wolf Gerald L | Method and apparatus for reversibly occluding a biological tube |
SE464558B (en) * | 1990-03-22 | 1991-05-13 | Hepar Ab | IMPLANTABLE DEVICE FOR SUSPENSION OF A CHANNEL IN THE BODY OF A LIVE BEING |
US5158548A (en) | 1990-04-25 | 1992-10-27 | Advanced Cardiovascular Systems, Inc. | Method and system for stent delivery |
US5250286A (en) * | 1990-05-07 | 1993-10-05 | Aegis Technology, Inc. | Treatment of chronic obstructive pulmonary disease (COPD) by inhalation of an imidazoline |
US5411552A (en) | 1990-05-18 | 1995-05-02 | Andersen; Henning R. | Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis |
DK124690D0 (en) | 1990-05-18 | 1990-05-18 | Henning Rud Andersen | FAT PROTECTION FOR IMPLEMENTATION IN THE BODY FOR REPLACEMENT OF NATURAL FLEET AND CATS FOR USE IN IMPLEMENTING A SUCH FAT PROTECTION |
US5116360A (en) | 1990-12-27 | 1992-05-26 | Corvita Corporation | Mesh composite graft |
US5147370A (en) * | 1991-06-12 | 1992-09-15 | Mcnamara Thomas O | Nitinol stent for hollow body conduits |
IT1247037B (en) | 1991-06-25 | 1994-12-12 | Sante Camilli | ARTIFICIAL VENOUS VALVE |
US5649906A (en) | 1991-07-17 | 1997-07-22 | Gory; Pierre | Method for implanting a removable medical apparatus in a human body |
US5161524A (en) | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
US5151105A (en) | 1991-10-07 | 1992-09-29 | Kwan Gett Clifford | Collapsible vessel sleeve implant |
US5876445A (en) | 1991-10-09 | 1999-03-02 | Boston Scientific Corporation | Medical stents for body lumens exhibiting peristaltic motion |
US5662713A (en) | 1991-10-09 | 1997-09-02 | Boston Scientific Corporation | Medical stents for body lumens exhibiting peristaltic motion |
US5123919A (en) | 1991-11-21 | 1992-06-23 | Carbomedics, Inc. | Combined prosthetic aortic heart valve and vascular graft |
IT1253903B (en) | 1991-12-05 | 1995-08-31 | Luigi Gigante | VALVE CATHETER FOR INCONTINENCE AND URINARY RETENTION |
US5382259A (en) * | 1992-10-26 | 1995-01-17 | Target Therapeutics, Inc. | Vasoocclusion coil with attached tubular woven or braided fibrous covering |
US5409019A (en) | 1992-10-30 | 1995-04-25 | Wilk; Peter J. | Coronary artery by-pass method |
DE4300285A1 (en) | 1993-01-08 | 1994-07-14 | Wolf Gmbh Richard | Instrument for implanting and extracting stents |
US5306234A (en) | 1993-03-23 | 1994-04-26 | Johnson W Dudley | Method for closing an atrial appendage |
EP0621015B1 (en) | 1993-04-23 | 1998-03-18 | Schneider (Europe) Ag | Stent with a covering layer of elastic material and method for applying the layer on the stent |
US5486154A (en) | 1993-06-08 | 1996-01-23 | Kelleher; Brian S. | Endoscope |
US5366478A (en) | 1993-07-27 | 1994-11-22 | Ethicon, Inc. | Endoscopic surgical sealing device |
US5437824A (en) * | 1993-12-23 | 1995-08-01 | Moghan Medical Corp. | Method of forming a molded silicone foam implant having open-celled interstices |
US5453090A (en) | 1994-03-01 | 1995-09-26 | Cordis Corporation | Method of stent delivery through an elongate softenable sheath |
US5645519A (en) | 1994-03-18 | 1997-07-08 | Jai S. Lee | Endoscopic instrument for controlled introduction of tubular members in the body and methods therefor |
US5392775A (en) | 1994-03-22 | 1995-02-28 | Adkins, Jr.; Claude N. | Duckbill valve for a tracheostomy tube that permits speech |
US5683451A (en) | 1994-06-08 | 1997-11-04 | Cardiovascular Concepts, Inc. | Apparatus and methods for deployment release of intraluminal prostheses |
US5417226A (en) | 1994-06-09 | 1995-05-23 | Juma; Saad | Female anti-incontinence device |
US5755770A (en) | 1995-01-31 | 1998-05-26 | Boston Scientific Corporatiion | Endovascular aortic graft |
DE29507519U1 (en) | 1995-05-05 | 1995-08-10 | Angiomed Ag | Endosphincter and set for releasable closing of the urethra |
US5741248A (en) * | 1995-06-07 | 1998-04-21 | Temple University-Of The Commonwealth System Of Higher Education | Fluorochemical liquid augmented cryosurgery |
US5645565A (en) | 1995-06-13 | 1997-07-08 | Ethicon Endo-Surgery, Inc. | Surgical plug |
US5588424A (en) * | 1995-06-28 | 1996-12-31 | The Cleveland Clinic Foundation | Bronchial blocker endotracheal apparatus |
US5833707A (en) * | 1995-07-05 | 1998-11-10 | Advanced Cardiovascular Systems, Inc. | Removable stent and method of deployment |
US5697968A (en) | 1995-08-10 | 1997-12-16 | Aeroquip Corporation | Check valve for intraluminal graft |
US5660175A (en) | 1995-08-21 | 1997-08-26 | Dayal; Bimal | Endotracheal device |
US5868704A (en) * | 1995-09-18 | 1999-02-09 | W. L. Gore & Associates, Inc. | Balloon catheter device |
DE19547538C2 (en) | 1995-12-20 | 1999-09-23 | Ruesch Willy Ag | Instrument for use in interventional flexible tracheoscopy / bronchoscopy |
US5853422A (en) * | 1996-03-22 | 1998-12-29 | Scimed Life Systems, Inc. | Apparatus and method for closing a septal defect |
KR980000327U (en) | 1996-06-13 | 1998-03-30 | 이정행 | Earring hole molding for earring installation |
US5855601A (en) | 1996-06-21 | 1999-01-05 | The Trustees Of Columbia University In The City Of New York | Artificial heart valve and method and device for implanting the same |
US6027508A (en) | 1996-10-03 | 2000-02-22 | Scimed Life Systems, Inc. | Stent retrieval device |
US5733329A (en) * | 1996-12-30 | 1998-03-31 | Target Therapeutics, Inc. | Vaso-occlusive coil with conical end |
US5919224A (en) * | 1997-02-12 | 1999-07-06 | Schneider (Usa) Inc | Medical device having a constricted region for occluding fluid flow in a body lumen |
US5851232A (en) | 1997-03-15 | 1998-12-22 | Lois; William A. | Venous stent |
GB2324729B (en) | 1997-04-30 | 2002-01-02 | Bradford Hospitals Nhs Trust | Lung treatment device |
US6287290B1 (en) | 1999-07-02 | 2001-09-11 | Pulmonx | Methods, systems, and kits for lung volume reduction |
US6293951B1 (en) | 1999-08-24 | 2001-09-25 | Spiration, Inc. | Lung reduction device, system, and method |
US6398775B1 (en) | 1999-10-21 | 2002-06-04 | Pulmonx | Apparatus and method for isolated lung access |
US6585639B1 (en) | 2000-10-27 | 2003-07-01 | Pulmonx | Sheath and method for reconfiguring lung viewing scope |
US6527761B1 (en) | 2000-10-27 | 2003-03-04 | Pulmonx, Inc. | Methods and devices for obstructing and aspirating lung tissue segments |
DE10302310A1 (en) | 2003-01-20 | 2004-07-29 | Freitag, Lutz, Dr. | Patient lung reduction method, e.g. for treating pulmonary emphysema, whereby a bronchial catheter is inserted into an over-swollen lung area and the supplying bronchopulmonary closed in synchronism with patient breathing |
-
1997
- 1997-04-30 GB GB9708681A patent/GB2324729B/en not_active Expired - Lifetime
-
1998
- 1998-03-03 US US09/762,692 patent/US7670373B1/en not_active Expired - Lifetime
- 1998-03-03 WO PCT/GB1998/000652 patent/WO1998048706A1/en active Application Filing
- 1998-03-03 AU AU66301/98A patent/AU6630198A/en not_active Abandoned
- 1998-03-03 EP EP01201457A patent/EP1157663A1/en not_active Ceased
-
2002
- 2002-05-28 HK HK02103976.0A patent/HK1043030A1/en unknown
-
2006
- 2006-09-01 US US11/515,181 patent/US20070005083A1/en not_active Abandoned
-
2010
- 2010-01-14 US US12/687,805 patent/US8136520B2/en not_active Expired - Fee Related
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0204218A1 (en) * | 1985-05-31 | 1986-12-10 | Stöckert Instrumente GmbH | Balloon catheter |
US4710192A (en) * | 1985-12-30 | 1987-12-01 | Liotta Domingo S | Diaphragm and method for occlusion of the descending thoracic aorta |
US5246445A (en) * | 1990-04-19 | 1993-09-21 | Instent Inc. | Device for the treatment of constricted ducts in human bodies |
DE4101936A1 (en) * | 1991-01-21 | 1992-07-23 | Fischer Matthias | Intravascular perfusion throttling device - consists of balloon with radially extending ribs |
DE9205797U1 (en) * | 1992-04-30 | 1992-06-17 | Schmitz-Rode, Thomas, Dipl.-Ing. Dr.Med. | |
US5382261A (en) * | 1992-09-01 | 1995-01-17 | Expandable Grafts Partnership | Method and apparatus for occluding vessels |
WO1994026175A1 (en) * | 1993-05-06 | 1994-11-24 | Vitaphore Corporation | Embolization device |
WO1995032018A1 (en) * | 1994-05-25 | 1995-11-30 | Teirstein Paul S | Body passageway closure apparatus and method |
Cited By (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8136520B2 (en) | 1997-04-30 | 2012-03-20 | Pulmonx Corporation | Occlusion device |
US6410536B1 (en) | 1998-03-31 | 2002-06-25 | Warner-Lambert Company | Quinoxalinones as serine protease inhibitors such as factor XA and thrombin |
US7458963B2 (en) | 1999-07-02 | 2008-12-02 | Pulmonx | Methods, systems, and kits for lung volume reduction |
WO2001002042A1 (en) | 1999-07-02 | 2001-01-11 | Pulmonx | Methods, systems, and kits for lung volume reduction |
US6287290B1 (en) | 1999-07-02 | 2001-09-11 | Pulmonx | Methods, systems, and kits for lung volume reduction |
US8177769B2 (en) | 1999-07-02 | 2012-05-15 | Pulmonx Corporation | Methods, systems, and kits for lung volume reduction |
US7766895B2 (en) | 1999-07-02 | 2010-08-03 | Pulmonx Corporation | Methods, systems, and kits for lung volume reduction |
US7141046B2 (en) | 1999-07-02 | 2006-11-28 | Pulmonx | Methods, systems, and kits for lung volume reduction |
US6709401B2 (en) | 1999-07-02 | 2004-03-23 | Pulmonx | Methods, systems, and kits for lung volume reduction |
US7186259B2 (en) | 1999-07-02 | 2007-03-06 | Pulmonx | Methods, systems, and kits for lung volume reduction |
US6878141B1 (en) | 1999-07-02 | 2005-04-12 | Pulmonx | Methods systems and kits for lung volume reduction |
AU2005202552C1 (en) * | 1999-08-05 | 2008-08-14 | Broncus Technologies, Inc. | Methods and devices for creating collateral channels in the lungs |
AU2005202552B2 (en) * | 1999-08-05 | 2008-07-03 | Broncus Technologies, Inc. | Methods and devices for creating collateral channels in the lungs |
US6293951B1 (en) * | 1999-08-24 | 2001-09-25 | Spiration, Inc. | Lung reduction device, system, and method |
US6258100B1 (en) | 1999-08-24 | 2001-07-10 | Spiration, Inc. | Method of reducing lung size |
US6694979B2 (en) | 2000-03-04 | 2004-02-24 | Emphasys Medical, Inc. | Methods and devices for use in performing pulmonary procedures |
US8474460B2 (en) | 2000-03-04 | 2013-07-02 | Pulmonx Corporation | Implanted bronchial isolation devices and methods |
US6679264B1 (en) * | 2000-03-04 | 2004-01-20 | Emphasys Medical, Inc. | Methods and devices for use in performing pulmonary procedures |
USRE45921E1 (en) | 2000-03-23 | 2016-03-15 | Spiration, Inc. | Tissue resection device, system, and method |
US6514290B1 (en) | 2000-03-31 | 2003-02-04 | Broncus Technologies, Inc. | Lung elastic recoil restoring or tissue compressing device and method |
AU2001260840B2 (en) * | 2000-05-18 | 2005-08-11 | Emphasys Medical, Inc. | Bronchiopulmonary occlusion devices and lung volume reduction methods |
WO2001087170A1 (en) * | 2000-05-18 | 2001-11-22 | Emphasys Medical, Inc. | Bronchiopulmonary occlusion devices and lung volume reduction methods |
WO2002022072A3 (en) * | 2000-09-11 | 2003-08-14 | Closure Medical Corp | Bronchial occlusion method and apparatus |
US6997918B2 (en) | 2000-10-27 | 2006-02-14 | Pulmonx | Methods and devices for obstructing and aspirating lung tissue segments |
US9492148B2 (en) | 2000-12-14 | 2016-11-15 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Apparatus and methods for sealing vascular punctures |
US8888812B2 (en) | 2000-12-14 | 2014-11-18 | Cordis Corporation | Plug with collet and apparatus and methods for delivering such plugs |
US9655602B2 (en) | 2000-12-14 | 2017-05-23 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Vascular plug having composite construction |
US8251067B2 (en) | 2001-03-02 | 2012-08-28 | Pulmonx Corporation | Bronchial flow control devices with membrane seal |
US7357795B2 (en) | 2001-07-19 | 2008-04-15 | Olympus Corporation | Medical device and method of embolizing bronchus or bronchiole |
US7144392B2 (en) | 2001-07-19 | 2006-12-05 | Olympus Corporation | Medical embolization element and method of embolizing tubular organ |
US10413244B2 (en) | 2001-09-10 | 2019-09-17 | Pulmonx Corporation | Method and apparatus for endobronchial diagnosis |
US8974484B2 (en) | 2001-09-11 | 2015-03-10 | Spiration, Inc. | Removable lung reduction devices, systems, and methods |
US7896887B2 (en) | 2001-10-25 | 2011-03-01 | Spiration, Inc. | Apparatus and method for deployment of a bronchial obstruction device |
US8986336B2 (en) | 2001-10-25 | 2015-03-24 | Spiration, Inc. | Apparatus and method for deployment of a bronchial obstruction device |
US8926647B2 (en) | 2002-03-20 | 2015-01-06 | Spiration, Inc. | Removable anchored lung volume reduction devices and methods |
EP1494657A4 (en) * | 2002-04-16 | 2009-02-18 | Spiration Inc | Removable anchored lung volume reduction devices and methods |
EP1494657A2 (en) * | 2002-04-16 | 2005-01-12 | Spiration, Inc. | Removable anchored lung volume reduction devices and methods |
WO2003088820A2 (en) * | 2002-04-19 | 2003-10-30 | Broncus Technologies, Inc. | Devices for maintaining surgically created openings |
WO2003088820A3 (en) * | 2002-04-19 | 2004-12-29 | Broncus Tech Inc | Devices for maintaining surgically created openings |
US8956319B2 (en) | 2002-05-17 | 2015-02-17 | Spiration, Inc. | One-way valve devices for anchored implantation in a lung |
US9533128B2 (en) | 2003-07-18 | 2017-01-03 | Broncus Medical Inc. | Devices for maintaining patency of surgically created channels in tissue |
US9622752B2 (en) | 2003-08-08 | 2017-04-18 | Spiration, Inc. | Bronchoscopic repair of air leaks in a lung |
US8974527B2 (en) | 2003-08-08 | 2015-03-10 | Spiration, Inc. | Bronchoscopic repair of air leaks in a lung |
US8852229B2 (en) | 2003-10-17 | 2014-10-07 | Cordis Corporation | Locator and closure device and method of use |
US11357960B2 (en) | 2004-07-19 | 2022-06-14 | Broncus Medical Inc. | Devices for delivering substances through an extra-anatomic opening created in an airway |
US10369339B2 (en) | 2004-07-19 | 2019-08-06 | Broncus Medical Inc. | Devices for delivering substances through an extra-anatomic opening created in an airway |
WO2006055683A2 (en) | 2004-11-16 | 2006-05-26 | Pulmonx | Occlusal stent and methods for its use |
WO2006055683A3 (en) * | 2004-11-16 | 2009-04-09 | Pulmonx | Occlusal stent and methods for its use |
US8409168B2 (en) | 2004-11-16 | 2013-04-02 | Pulmonx Corporation | Pulmonary occlusal stent delivery catheter, loading system and methods of use |
WO2006055692A2 (en) | 2004-11-16 | 2006-05-26 | Pulmonx | Pulmonary occlusal stent delivery catheter, loading system and methods of use |
EP3295990A2 (en) | 2004-11-16 | 2018-03-21 | Pulmonx | Pulmonary occlusal stent delivery catheter and loading system |
US9131942B2 (en) | 2004-11-16 | 2015-09-15 | Pulmonx Corporation | Pulmonary occlusal stent delivery catheter, loading system and methods of use |
US9872755B2 (en) | 2004-11-19 | 2018-01-23 | Pulmonx Corporation | Implant loading device and system |
US9211181B2 (en) | 2004-11-19 | 2015-12-15 | Pulmonx Corporation | Implant loading device and system |
US8388682B2 (en) | 2004-11-19 | 2013-03-05 | Pulmonx Corporation | Bronchial flow control devices and methods of use |
US11083556B2 (en) | 2004-11-19 | 2021-08-10 | Pulmonx Corporation | Implant loading device and system |
US11413045B2 (en) | 2005-01-20 | 2022-08-16 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
US10758239B2 (en) | 2005-01-20 | 2020-09-01 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
US11883029B2 (en) | 2005-01-20 | 2024-01-30 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
US9533116B2 (en) | 2005-01-20 | 2017-01-03 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
US8926654B2 (en) | 2005-05-04 | 2015-01-06 | Cordis Corporation | Locator and closure device and method of use |
US9289198B2 (en) | 2005-05-04 | 2016-03-22 | Cordis Corporation | Locator and closure device and method of use |
CN101460113B (en) * | 2006-03-31 | 2012-06-13 | 斯波瑞申有限公司 | Articulable anchor |
US7691151B2 (en) | 2006-03-31 | 2010-04-06 | Spiration, Inc. | Articulable Anchor |
US9198669B2 (en) | 2006-03-31 | 2015-12-01 | Spiration, Inc. | Articulable anchor |
US9913969B2 (en) | 2006-10-05 | 2018-03-13 | Broncus Medical Inc. | Devices for delivering substances through an extra-anatomic opening created in an airway |
US8100959B2 (en) | 2007-03-09 | 2012-01-24 | Pulmonx Corporation | Loading device for a pulmonary implant |
US9050094B2 (en) | 2007-03-12 | 2015-06-09 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
US11298489B2 (en) | 2007-03-12 | 2022-04-12 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
US10314992B2 (en) | 2007-03-12 | 2019-06-11 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
US9326873B2 (en) | 2007-10-12 | 2016-05-03 | Spiration, Inc. | Valve loader method, system, and apparatus |
JP2009297548A (en) * | 2009-09-28 | 2009-12-24 | Olympus Corp | Medical obturator |
US10631938B2 (en) | 2011-05-13 | 2020-04-28 | Broncus Medical Inc. | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
US9993306B2 (en) | 2011-05-13 | 2018-06-12 | Broncus Medical Inc. | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
US9486229B2 (en) | 2011-05-13 | 2016-11-08 | Broncus Medical Inc. | Methods and devices for excision of tissue |
US9421070B2 (en) | 2011-05-13 | 2016-08-23 | Broncus Medical Inc. | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
US9345532B2 (en) | 2011-05-13 | 2016-05-24 | Broncus Medical Inc. | Methods and devices for ablation of tissue |
US8932316B2 (en) | 2011-05-13 | 2015-01-13 | Broncus Medical Inc. | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
US10350048B2 (en) | 2011-09-23 | 2019-07-16 | Pulmonx Corporation | Implant loading device and system |
US10272260B2 (en) | 2011-11-23 | 2019-04-30 | Broncus Medical Inc. | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
JP2012130726A (en) * | 2012-02-20 | 2012-07-12 | Olympus Corp | Obturator for medical treatment |
JP7333030B2 (en) | 2019-09-24 | 2023-08-24 | 国立大学法人 長崎大学 | fistula treatment instrument |
Also Published As
Publication number | Publication date |
---|---|
US20070005083A1 (en) | 2007-01-04 |
GB9708681D0 (en) | 1997-06-18 |
GB2324729B (en) | 2002-01-02 |
US8136520B2 (en) | 2012-03-20 |
GB2324729A8 (en) | 2001-02-21 |
GB2324729A (en) | 1998-11-04 |
AU6630198A (en) | 1998-11-24 |
HK1043030A1 (en) | 2002-09-06 |
EP1157663A1 (en) | 2001-11-28 |
US20100114157A1 (en) | 2010-05-06 |
US7670373B1 (en) | 2010-03-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US7670373B1 (en) | Occlusion device | |
AU2003225044B2 (en) | Removable anchored lung volume reduction devices and methods | |
US9358013B2 (en) | One-way valve devices for anchored implantation in a lung | |
US6514290B1 (en) | Lung elastic recoil restoring or tissue compressing device and method | |
US8986336B2 (en) | Apparatus and method for deployment of a bronchial obstruction device | |
US8021385B2 (en) | Removable anchored lung volume reduction devices and methods | |
WO2003022124A2 (en) | Removable lung reduction devices, systems, and methods | |
EP2353557B1 (en) | Removable anchored lung volume reduction devices | |
WO2001074271A1 (en) | Lung elastic recoil restoring/compression device | |
AU2002349977A1 (en) | Bronchial obstruction device deployment system and method |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1998908220 Country of ref document: EP |
|
NENP | Non-entry into the national phase |
Ref country code: JP Ref document number: 1998546692 Format of ref document f/p: F |
|
NENP | Non-entry into the national phase |
Ref country code: CA |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1998908220 Country of ref document: EP |
|
122 | Ep: pct application non-entry in european phase | ||
WWE | Wipo information: entry into national phase |
Ref document number: 09762692 Country of ref document: US |