WO1998051304A1 - Benzimidazole-2-carbamates for the treatment of viral infections and cancer - Google Patents
Benzimidazole-2-carbamates for the treatment of viral infections and cancer Download PDFInfo
- Publication number
- WO1998051304A1 WO1998051304A1 PCT/US1997/021565 US9721565W WO9851304A1 WO 1998051304 A1 WO1998051304 A1 WO 1998051304A1 US 9721565 W US9721565 W US 9721565W WO 9851304 A1 WO9851304 A1 WO 9851304A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pharmaceutical composition
- composition according
- agents
- benzimidazole derivative
- cancer
- Prior art date
Links
- 0 COC(*1(CC1)C1=C=*CCc(ccc(C(CCCCCI)=O)c2)c2S1)=O Chemical compound COC(*1(CC1)C1=C=*CCc(ccc(C(CCCCCI)=O)c2)c2S1)=O 0.000 description 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002268840A CA2268840C (en) | 1997-05-16 | 1997-11-26 | Benzimidazole-2-carbamates for the treatment of viral infections and cancer |
IL12935297A IL129352A0 (en) | 1997-05-16 | 1997-11-26 | Benzimidazole-2- carbamates for the treatment of viral infections and cancer |
NZ335159A NZ335159A (en) | 1997-05-16 | 1997-11-26 | Benzimidazole-2-carbamates for the treatment of HIV, viral infections and inhibits the growth of cancers and tumours |
DE69737793T DE69737793D1 (en) | 1997-05-16 | 1997-11-26 | BENZIMIDAZOLE-2-CARBAMATE FOR THE TREATMENT OF VIRAL INFECTIONS AND CANCER |
EP97949600A EP0956017B1 (en) | 1997-05-16 | 1997-11-26 | Benzimidazole-2-carbamates for the treatment of viral infections and cancer |
PL97335541A PL335541A1 (en) | 1997-05-16 | 1997-11-26 | Benzoimidazol-2-carbamates for treating viral infections and carcinoma |
AU74027/98A AU728690B2 (en) | 1997-05-16 | 1997-11-26 | Benzimidazole-2-carbamates for the treatment of viral infections and cancer |
SK470-99A SK47099A3 (en) | 1997-05-16 | 1997-11-26 | Benzimidazole-2-carbamates for the treatment of viral infections and cancer |
HU0001170A HUP0001170A3 (en) | 1997-05-16 | 1997-11-26 | Pharmaceutical compositions containing benzimidazole-2-carbamate derivatives as active ingredients for the treatment of viral infections and cancer |
JP52193098A JP2001527523A (en) | 1997-05-16 | 1997-11-26 | Benzimidazole-2-carbamate for the treatment of viral infections and cancer |
NO991700A NO991700L (en) | 1997-05-16 | 1999-04-09 | Benzimidazole-2-carbamates for the treatment of viral infections and cancer |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/857,811 US6506783B1 (en) | 1997-05-16 | 1997-05-16 | Cancer treatments and pharmaceutical compositions therefor |
US08/857,811 | 1997-05-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998051304A1 true WO1998051304A1 (en) | 1998-11-19 |
Family
ID=25326784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/021565 WO1998051304A1 (en) | 1997-05-16 | 1997-11-26 | Benzimidazole-2-carbamates for the treatment of viral infections and cancer |
Country Status (22)
Country | Link |
---|---|
US (13) | US6506783B1 (en) |
EP (1) | EP0956017B1 (en) |
JP (1) | JP2001527523A (en) |
KR (1) | KR20000049065A (en) |
CN (1) | CN1254282A (en) |
AR (1) | AR010008A1 (en) |
AT (1) | ATE363904T1 (en) |
AU (1) | AU728690B2 (en) |
BR (1) | BR9714634A (en) |
CA (1) | CA2268840C (en) |
CZ (1) | CZ125299A3 (en) |
DE (1) | DE69737793D1 (en) |
HU (1) | HUP0001170A3 (en) |
IL (1) | IL129352A0 (en) |
NO (1) | NO991700L (en) |
NZ (1) | NZ335159A (en) |
PE (1) | PE11099A1 (en) |
PL (1) | PL335541A1 (en) |
SK (1) | SK47099A3 (en) |
TR (1) | TR199901528T2 (en) |
WO (1) | WO1998051304A1 (en) |
ZA (1) | ZA979096B (en) |
Cited By (24)
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WO2001012169A2 (en) * | 1999-08-13 | 2001-02-22 | The Procter & Gamble Company | Method of cancer treatment |
US6228876B1 (en) | 1995-06-07 | 2001-05-08 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of cancers |
US6245789B1 (en) | 1998-05-19 | 2001-06-12 | The Procter & Gamble Company | HIV and viral treatment |
US6262093B1 (en) | 1995-04-12 | 2001-07-17 | The Proctor & Gamble Company | Methods of treating cancer with benzimidazoles |
US6265427B1 (en) | 1995-06-07 | 2001-07-24 | The Proctor & Gamble Company | Pharmaceutical composition for the method of treating leukemia |
US6271217B1 (en) | 1997-01-28 | 2001-08-07 | The Procter & Gamble Company | Method of treating cancer with a benzimidazole and a chemotherapeutic agent |
WO2001089499A2 (en) * | 2000-05-25 | 2001-11-29 | The Procter & Gamble Company | Use of pyridinylimidazole carbamate derivate for the manufacture of a medicament for the treatment of cancer |
US6380232B1 (en) | 2000-09-26 | 2002-04-30 | The Procter & Gamble Company | Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof |
WO2002041891A2 (en) * | 2000-11-01 | 2002-05-30 | The Procter & Gamble Company | Hiv treatment with benzimidazoles |
US6407105B1 (en) * | 2000-09-26 | 2002-06-18 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
US6407131B1 (en) | 1997-05-16 | 2002-06-18 | The Procter & Gamble Company | Compounds and method for use thereof in the treatment of cancer or viral infections |
WO2002067932A1 (en) * | 2001-01-11 | 2002-09-06 | Board Of Regents, The University Of Texas System | Antihelminthic drugs as a treatment for hyperproliferative diseases |
US6462062B1 (en) | 2000-09-26 | 2002-10-08 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
US6479526B1 (en) | 1995-04-12 | 2002-11-12 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of viruses and cancers |
US6498188B1 (en) | 1995-04-12 | 2002-12-24 | The Procter & Gamble Company | Methods of treatment for cancer or viral infections |
US6608096B1 (en) | 2000-09-26 | 2003-08-19 | University Of Arizona Foundation | Compounds and methods for use thereof in the treatment of cancer or viral infections |
EP1363625A1 (en) * | 2001-01-24 | 2003-11-26 | Combinatorx, Incorporated | Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders |
US6686391B2 (en) | 1995-08-04 | 2004-02-03 | University Of Arizona Foundation | N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions |
US7022712B2 (en) | 2002-03-26 | 2006-04-04 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Solubilization of weak bases |
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