WO1999002671A1 - In vitro sorting method - Google Patents
In vitro sorting method Download PDFInfo
- Publication number
- WO1999002671A1 WO1999002671A1 PCT/GB1998/001889 GB9801889W WO9902671A1 WO 1999002671 A1 WO1999002671 A1 WO 1999002671A1 GB 9801889 W GB9801889 W GB 9801889W WO 9902671 A1 WO9902671 A1 WO 9902671A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- gene product
- genetic elements
- genetic
- microcapsule
- gene
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1062—Isolating an individual clone by screening libraries mRNA-Display, e.g. polypeptide and encoding template are connected covalently
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
Abstract
Description
Claims
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2295324A CA2295324C (en) | 1997-07-07 | 1998-06-29 | In vitro sorting method |
EP98930958A EP1019496B1 (en) | 1997-07-07 | 1998-06-29 | In vitro sorting method |
AU81231/98A AU736836B2 (en) | 1997-07-07 | 1998-06-29 | In vitro sorting method |
DK98930958T DK1019496T3 (en) | 1997-07-07 | 1998-06-29 | In vitro sorting method |
DK04077102T DK1496120T3 (en) | 1997-07-07 | 1998-06-29 | In vitro sorting method |
JP2000502169A JP4298912B2 (en) | 1997-07-07 | 1998-06-29 | In vitro sorting method |
GB9929447A GB2342094B (en) | 1997-07-07 | 1998-06-29 | In vitro sorting method |
AT98930958T ATE278013T1 (en) | 1997-07-07 | 1998-06-29 | IN VITRO SELECTION METHOD |
DE69826697T DE69826697T2 (en) | 1997-07-07 | 1998-06-29 | IN VITRO SELECTION METHOD |
US09/464,122 US6489103B1 (en) | 1997-07-07 | 1999-12-16 | In vitro sorting method |
US10/263,984 US7138233B2 (en) | 1997-07-07 | 2002-10-03 | IN vitro sorting method |
US10/860,750 US7252943B2 (en) | 1997-07-07 | 2004-06-03 | In Vitro sorting method |
US10/861,930 US7638276B2 (en) | 1997-07-07 | 2004-06-04 | In vitro sorting method |
US11/518,094 US7582446B2 (en) | 1997-07-07 | 2006-09-08 | In vitro sorting method |
US11/820,903 US8367326B2 (en) | 1997-07-07 | 2007-06-21 | In vitro sorting method |
US13/733,473 US9528106B2 (en) | 1997-07-07 | 2013-01-03 | In vitro sorting method |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9714300.2A GB9714300D0 (en) | 1997-07-07 | 1997-07-07 | In vitro sorting method |
GB9714300.2 | 1997-07-07 | ||
GBGB9806393.6A GB9806393D0 (en) | 1998-03-25 | 1998-03-25 | In vitro sorting method |
GB9806393.6 | 1998-03-25 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/464,122 Continuation US6489103B1 (en) | 1997-07-07 | 1999-12-16 | In vitro sorting method |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999002671A1 true WO1999002671A1 (en) | 1999-01-21 |
Family
ID=26311843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1998/001889 WO1999002671A1 (en) | 1997-07-07 | 1998-06-29 | In vitro sorting method |
Country Status (13)
Country | Link |
---|---|
US (7) | US6489103B1 (en) |
EP (6) | EP1908832B1 (en) |
JP (3) | JP4298912B2 (en) |
AT (4) | ATE358177T1 (en) |
AU (1) | AU736836B2 (en) |
CA (3) | CA2295324C (en) |
CY (1) | CY1111537T1 (en) |
DE (4) | DE69841997D1 (en) |
DK (3) | DK1801214T3 (en) |
ES (4) | ES2230701T3 (en) |
GB (1) | GB2342094B (en) |
PT (2) | PT1496120E (en) |
WO (1) | WO1999002671A1 (en) |
Cited By (86)
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WO2000040712A1 (en) | 1999-01-07 | 2000-07-13 | Medical Research Council | Optical sorting method |
WO2002022869A2 (en) * | 2000-09-13 | 2002-03-21 | Medical Research Council | Directed evolution method |
US6410241B1 (en) | 1999-03-24 | 2002-06-25 | Board Of Regents, The University Of Texas System | Methods of screening open reading frames to determine whether they encode polypeptides with an ability to generate an immune response |
WO2002090537A1 (en) * | 2001-05-02 | 2002-11-14 | Riken | Process for synthesizing protein using cell-free protein synthesis system |
WO2002103011A2 (en) * | 2001-06-18 | 2002-12-27 | Medical Research Council | Selective gene amplification |
WO2003044187A2 (en) * | 2001-11-16 | 2003-05-30 | Medical Research Council | Emulsion compositions |
WO2003106678A1 (en) * | 2002-06-13 | 2003-12-24 | Nucleics Pty Ltd | Dna amplification and sequencing in collapsible emulsions |
WO2004024917A2 (en) * | 2002-09-11 | 2004-03-25 | Medical Research Council | Single-molecule in vitro evolution |
WO2004058820A2 (en) | 2002-12-27 | 2004-07-15 | Domantis Limited | Single-domain-effector group and its uses |
WO2005003375A2 (en) | 2003-01-29 | 2005-01-13 | 454 Corporation | Methods of amplifying and sequencing nucleic acids |
WO2005030957A1 (en) * | 2003-10-01 | 2005-04-07 | ETH Zürich | Method for in vitro evolution of polypeptides |
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US6955877B1 (en) | 1999-07-20 | 2005-10-18 | Affibody Ab | In vitro selection and optional identification of polypeptides using solid support carriers |
WO2006018650A2 (en) * | 2004-08-20 | 2006-02-23 | Domantis Limited | Method of in vitro polypeptide selection using the arc dna binding domain fused to the polypeptide to be selected |
US20060153924A1 (en) * | 2003-03-31 | 2006-07-13 | Medical Research Council | Selection by compartmentalised screening |
EP1691792A2 (en) * | 2003-11-24 | 2006-08-23 | YEDA RESEARCH AND DEVELOPMENT Co. LTD. | Compositions and methods for in vitro sorting of molecular and cellular libraries |
EP1801212A1 (en) * | 2005-12-21 | 2007-06-27 | Eidgenössische Technische Hochschule Zürich | Selection of biocatalysts for chemical synthesis |
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US7262055B2 (en) | 1998-08-25 | 2007-08-28 | Gendaq Limited | Regulated gene expression in plants |
AU2004242526B2 (en) * | 1999-01-07 | 2007-08-30 | United Kingdom Research And Innovation | Optical Sorting Method |
US7285416B2 (en) | 2000-01-24 | 2007-10-23 | Gendaq Limited | Regulated gene expression in plants |
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