WO1999017742A3 - Taste masked formulations - Google Patents
Taste masked formulations Download PDFInfo
- Publication number
- WO1999017742A3 WO1999017742A3 PCT/IE1998/000081 IE9800081W WO9917742A3 WO 1999017742 A3 WO1999017742 A3 WO 1999017742A3 IE 9800081 W IE9800081 W IE 9800081W WO 9917742 A3 WO9917742 A3 WO 9917742A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- powders
- taste
- micromatrix
- drug
- masked
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU91824/98A AU9182498A (en) | 1997-10-03 | 1998-09-30 | Taste masked formulations |
JP2000514619A JP2001518490A (en) | 1997-10-03 | 1998-09-30 | Taste-masked preparation |
EP98944190A EP1027036A2 (en) | 1997-10-03 | 1998-09-30 | Taste masked formulations |
CA002304630A CA2304630A1 (en) | 1997-10-03 | 1998-09-30 | Taste masked formulations |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6089497P | 1997-10-03 | 1997-10-03 | |
US60/060,894 | 1997-10-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999017742A2 WO1999017742A2 (en) | 1999-04-15 |
WO1999017742A3 true WO1999017742A3 (en) | 1999-06-17 |
Family
ID=22032403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IE1998/000081 WO1999017742A2 (en) | 1997-10-03 | 1998-09-30 | Taste masked formulations |
Country Status (7)
Country | Link |
---|---|
US (1) | US6153220A (en) |
EP (1) | EP1027036A2 (en) |
JP (1) | JP2001518490A (en) |
AU (1) | AU9182498A (en) |
CA (1) | CA2304630A1 (en) |
WO (1) | WO1999017742A2 (en) |
ZA (1) | ZA989013B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8936813B2 (en) | 2001-11-01 | 2015-01-20 | Novartis Ag | Spray drying methods and related compositions |
US9120031B2 (en) | 2000-11-09 | 2015-09-01 | Nektar Therapeutics | Compositions of particulate coformulation |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6395303B1 (en) * | 1996-06-10 | 2002-05-28 | Edward Mendell Co., Inc. | Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose |
US6057139A (en) | 1995-06-29 | 2000-05-02 | Mcneil-Ppc, Inc. | Preblend of microcrystalline cellulose and lactase for making tablets |
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
WO2000002574A1 (en) * | 1998-07-08 | 2000-01-20 | Kirin-Amgen Inc. | Powdery preparation for mucosal administration containing polymeric medicine |
DE19918435A1 (en) * | 1998-07-23 | 2000-01-27 | Roehm Gmbh | Coating or binding agent for medicaments, prepared using finely divided acrylic copolymer powder, used e.g. for taste-masking coatings or in transdermal delivery systems |
EP1231896A4 (en) * | 1999-11-16 | 2003-07-09 | Ranbaxy Lab Ltd | Taste masked oral compositions |
KR100863146B1 (en) * | 2000-07-17 | 2008-10-14 | 아스텔라스세이야쿠 가부시키가이샤 | Pharmaceutical composition improved in peroral absorbability |
JP4446463B2 (en) * | 2000-10-16 | 2010-04-07 | 第一三共株式会社 | Oral rapidly disintegrating pharmaceutical composition and method for producing the same |
FR2826274B1 (en) * | 2001-06-21 | 2003-09-26 | Aventis Pharma Sa | PHARMACEUTICAL FORMULATION FOR MASK TASTE AND METHOD FOR PREPARING THE SAME |
GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
US6753017B2 (en) * | 2001-11-07 | 2004-06-22 | Jrs Pharma Lp | Process for preparing dry extracts |
AU2002217982A1 (en) * | 2001-11-29 | 2003-06-17 | Penwest Pharmaceutical Company | Process for co-spray drying liquid herbal extracts with dry silicified mcc |
US7179488B2 (en) * | 2001-11-29 | 2007-02-20 | Bob Sherwood | Process for co-spray drying liquid herbal extracts with dry silicified MCC |
US20030206978A1 (en) * | 2001-11-29 | 2003-11-06 | Bob Sherwood | Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose |
US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
US6930119B2 (en) * | 2002-07-17 | 2005-08-16 | Reliant Pharmaceuticals, Inc. | Liquid pharmaceutical composition |
RU2005109909A (en) * | 2002-09-04 | 2006-10-10 | Рэнбакси Лабораториз Лимитед (In) | MEDICINAL FORMS WITH MASKED TASTE AND METHODS FOR PRODUCING THEM |
EP1555996A2 (en) * | 2002-10-31 | 2005-07-27 | Euro-Celtique | Pharmaceutical identification |
US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
DE10304403A1 (en) | 2003-01-28 | 2004-08-05 | Röhm GmbH & Co. KG | Process for the preparation of an oral dosage form with immediate disintegration and drug release |
US20050196439A1 (en) * | 2003-10-24 | 2005-09-08 | J. Rettenmaier & Soehne Gmbh + Co. Kg | Process for co-spray drying agents with dry silicified MCC |
EP1694302A1 (en) * | 2003-12-15 | 2006-08-30 | Council of Scientific and Industrial Research | TASTE MASKED PHARMACEUTICAL COMPOSITIONS COMPRISING BITTER DRUG AND pH SENSITIVE POLYMER |
EP1694303A1 (en) * | 2003-12-15 | 2006-08-30 | Council Of Scientific And Industrial Research | Taste masked pharmaceutical composition comprising ph sensitive polymer |
US20060024335A1 (en) * | 2004-07-29 | 2006-02-02 | Roger Stier E | Oral compositions which mask the bitter taste of a bitter-tasting agent |
WO2006016602A1 (en) * | 2004-08-10 | 2006-02-16 | Ajinomoto Co., Inc. | Nateglinide-containing preparation reduced in bitterness |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
ES2360293T5 (en) * | 2004-10-01 | 2014-06-02 | Firmenich Sa | Perfume or flavoring microcapsules comprising an explosion suppressor |
US8057820B2 (en) * | 2004-10-08 | 2011-11-15 | Mcneil-Ppc, Inc. | Enteric coated aspirin granules comingled with binder |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
US20060105039A1 (en) | 2004-10-21 | 2006-05-18 | Jin-Wang Lai | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
US20060228487A1 (en) * | 2005-04-11 | 2006-10-12 | J. Rettenmaier & Söehne GmbH + Co. KG | Methods of combining active agents with augmented microcrystalline cellulose |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
US20070134277A1 (en) * | 2005-12-09 | 2007-06-14 | Children's Medical Center Corporation | Pharmaceutical formulation for sulfur-containing drugs in liquid dosage forms |
US20070286903A1 (en) * | 2006-06-13 | 2007-12-13 | Becicka Brian T | Composition and method for taste masking |
PL2425820T3 (en) | 2007-02-11 | 2015-08-31 | Map Pharmaceuticals Inc | Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile |
ES2406939T3 (en) * | 2007-10-19 | 2013-06-10 | Otsuka Pharmaceutical Co., Ltd. | Pharmaceutical solid matrix preparation |
CN108159019A (en) | 2009-12-02 | 2018-06-15 | 阿黛尔药物有限公司 | Fexofenadine microcapsules and the composition containing fexofenadine microcapsules |
CA2783877A1 (en) * | 2009-12-10 | 2011-06-16 | A. Mark Schobel | Ph sensitive compounds in taste masking within oral thin film strips |
JP5915014B2 (en) * | 2010-07-30 | 2016-05-11 | 大正製薬株式会社 | Oral solution |
US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
US9808030B2 (en) | 2011-02-11 | 2017-11-07 | Grain Processing Corporation | Salt composition |
WO2013022948A1 (en) | 2011-08-08 | 2013-02-14 | The Coca-Cola Company | Cell lines comprising endogenous taste receptors and their uses |
US11957792B2 (en) * | 2012-04-19 | 2024-04-16 | Glatt Ag | Taste-masked pharmaceutical compositions containing diclofenac |
GR1008992B (en) | 2015-12-17 | 2017-03-23 | Verisfield (Uk) Ltd, Υποκαταστημα Ελλαδας, Εμπορια Φαρμακων | Oral pharmaceutical composition in the form of granules comprising metronidazole or derivatives thereofand a taste-masking agent |
US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
BR112018072539A2 (en) | 2016-05-05 | 2019-03-26 | Aquestive Therapeutics, Inc. | increased administration epinephrine compositions |
AU2017282039B2 (en) * | 2016-06-21 | 2022-01-06 | Laila Nutraceuticals | Taste masking formulation for bitter natural compounds |
CN114522166B (en) * | 2022-04-22 | 2022-09-30 | 北京剂泰医药科技有限公司 | Solid dispersion composition and preparation method and application thereof |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2325388A1 (en) * | 1975-09-29 | 1977-04-22 | Meiji Seika Kaisha | PROCESS FOR THE PREPARATION OF BITTER-FREE COMPOSITIONS FOR ORAL ADMINISTRATION |
JPS59129246A (en) * | 1983-01-12 | 1984-07-25 | Katayama Chem Works Co Ltd | Easily dispersible granular composition |
GB2166651A (en) * | 1984-10-30 | 1986-05-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
EP0266113A1 (en) * | 1986-10-21 | 1988-05-04 | American Home Products Corporation | Spray dried acetaminophen |
EP0277042A2 (en) * | 1987-01-30 | 1988-08-03 | Taisho Pharmaceutical Co. Ltd | Orally administrable pharmaceutical preparation of improved flavoring characteristics |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4708867A (en) * | 1983-12-19 | 1987-11-24 | Key Pharmaceuticals, Inc. | Minipellets |
-
1998
- 1998-09-30 US US09/163,731 patent/US6153220A/en not_active Expired - Fee Related
- 1998-09-30 JP JP2000514619A patent/JP2001518490A/en active Pending
- 1998-09-30 CA CA002304630A patent/CA2304630A1/en not_active Abandoned
- 1998-09-30 WO PCT/IE1998/000081 patent/WO1999017742A2/en not_active Application Discontinuation
- 1998-09-30 EP EP98944190A patent/EP1027036A2/en not_active Ceased
- 1998-09-30 AU AU91824/98A patent/AU9182498A/en not_active Abandoned
- 1998-10-02 ZA ZA989013A patent/ZA989013B/en unknown
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2325388A1 (en) * | 1975-09-29 | 1977-04-22 | Meiji Seika Kaisha | PROCESS FOR THE PREPARATION OF BITTER-FREE COMPOSITIONS FOR ORAL ADMINISTRATION |
JPS59129246A (en) * | 1983-01-12 | 1984-07-25 | Katayama Chem Works Co Ltd | Easily dispersible granular composition |
GB2166651A (en) * | 1984-10-30 | 1986-05-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
US4952402A (en) * | 1984-10-30 | 1990-08-28 | Elan Corporation, P.L.C. | Controlled release powder and process for its preparation |
EP0266113A1 (en) * | 1986-10-21 | 1988-05-04 | American Home Products Corporation | Spray dried acetaminophen |
US4760093A (en) * | 1986-10-21 | 1988-07-26 | American Home Products Corporation (Del.) | Spray dried acetaminophen |
EP0277042A2 (en) * | 1987-01-30 | 1988-08-03 | Taisho Pharmaceutical Co. Ltd | Orally administrable pharmaceutical preparation of improved flavoring characteristics |
Non-Patent Citations (2)
Title |
---|
DATABASE WPI Week 8436, Derwent World Patents Index; AN 84-221827, XP002098759 * |
M:L: LORENZO-LAMOSA ET AL.: "DEVELOPMENT OF A MICROENCAPSULATED FORM OF CEFUROXIME AXETIL USING PH-SENSITIVE ACRYLIC POLYMERS", JOURNAL OF MICROENCAPSULATION, vol. 14, no. 5, September 1997 (1997-09-01), LONDON(GB), pages 607 - 616, XP000659517 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9120031B2 (en) | 2000-11-09 | 2015-09-01 | Nektar Therapeutics | Compositions of particulate coformulation |
US8936813B2 (en) | 2001-11-01 | 2015-01-20 | Novartis Ag | Spray drying methods and related compositions |
Also Published As
Publication number | Publication date |
---|---|
AU9182498A (en) | 1999-04-27 |
WO1999017742A2 (en) | 1999-04-15 |
EP1027036A2 (en) | 2000-08-16 |
CA2304630A1 (en) | 1999-04-15 |
ZA989013B (en) | 1999-04-13 |
JP2001518490A (en) | 2001-10-16 |
US6153220A (en) | 2000-11-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1999017742A3 (en) | Taste masked formulations | |
CA2198630A1 (en) | Acetaminophen sustained-release formulation | |
CA2232450A1 (en) | Oral pharmaceutical composition containing antimicrobial actives and sustained release pantoprazole | |
CA2281473A1 (en) | Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same | |
CA2427815A1 (en) | Controlled release hydrocodone formulations | |
CA2407072A1 (en) | Taste masking coating composition | |
CA2258095A1 (en) | Tetrahydrolipstatin containing compositions | |
CA2377299A1 (en) | Mesalazine controlled release oral pharmaceutical compositions | |
WO1999059544A3 (en) | Orally disintegrable tablets | |
WO1998009597A3 (en) | Cushioning beads and tablet comprising the same capable of forming a suspension | |
WO2001087329A8 (en) | Liquid pharmaceutical composition containing an erythropoietin derivate | |
NO975872D0 (en) | Formulations for controlled release of poorly soluble drugs | |
CA2265766A1 (en) | Rapidly disintegrating pellets | |
CA2355854A1 (en) | Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations | |
CA2285266A1 (en) | Extended release formulations of erythromycin derivatives | |
CA2362816A1 (en) | Valdecoxib compositions | |
CA2266629A1 (en) | Taste-masked microcapsule compositions and methods of manufacture | |
RO116342B1 (en) | Oral liquid pharmaceutical composition | |
CA2330480A1 (en) | Controlled release formulation of divalproex sodium | |
CA2342634A1 (en) | Pharmaceutical composition comprising entacapone or nitecapone as well as a cross-linked cellulose derivative | |
AU764280C (en) | Process for the preparation of pellets with a content of up to 90 wt. per cent of a pharmaceutical active ingredient | |
CA2339913A1 (en) | Pharmaceutical formulations and method for making | |
CA2143413A1 (en) | Local Drug Delivery Film, for Periodontal Treatment | |
CA2383212A1 (en) | Controlled release oral dosage suitable for oral administration | |
CA2202397A1 (en) | Compositions comprising carbonate/bicarbonate buffered dichloroacetic acid and methods for treatment of metabolic and cardiovascular disorders |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
ENP | Entry into the national phase |
Ref document number: 2304630 Country of ref document: CA Ref country code: CA Ref document number: 2304630 Kind code of ref document: A Format of ref document f/p: F |
|
NENP | Non-entry into the national phase |
Ref country code: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1998944190 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWP | Wipo information: published in national office |
Ref document number: 1998944190 Country of ref document: EP |
|
WWR | Wipo information: refused in national office |
Ref document number: 1998944190 Country of ref document: EP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1998944190 Country of ref document: EP |