WO1999022651A1 - Dispositif medical pour placer un element in vivo a demeure et methode de placement de cet element - Google Patents
Dispositif medical pour placer un element in vivo a demeure et methode de placement de cet element Download PDFInfo
- Publication number
- WO1999022651A1 WO1999022651A1 PCT/JP1998/004894 JP9804894W WO9922651A1 WO 1999022651 A1 WO1999022651 A1 WO 1999022651A1 JP 9804894 W JP9804894 W JP 9804894W WO 9922651 A1 WO9922651 A1 WO 9922651A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- coil
- vivo indwelling
- wire
- catheter
- connecting member
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12163—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a string of elements connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/1215—Coils or wires comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
- A61B2017/12054—Details concerning the detachment of the occluding device from the introduction device
- A61B2017/12068—Details concerning the detachment of the occluding device from the introduction device detachable by heat
Definitions
- the present invention relates to a medical device for arranging a required indwelling member at a desired location in a living body through a tubular organ, and a method of arranging the in vivo indwelling member using the same.
- embolic materials for closing tubular organs such as catheters, guide wires, blood vessels, etc.
- Various medical devices have been developed and put into practical use.
- detachable balloons, coils, liquid embolic substances, particulate embolic substances, and the like are used as tubular organ embolic materials.
- these embolic materials which are usually placed in tubular organs, etc., are rarely collected or corrected if they are left or released in the wrong position. It is impossible. Under these circumstances, even if it has been conventionally impossible to place it at the target location, it is possible to pull it back and put it back in again.After confirming the placement location, remove the embolic material and place it there A removable embolic material has been proposed that can be used.
- Japanese Unexamined Patent Publication No. Hei 5-50032 / 1990 and Japanese Unexamined Patent Publication No. Hei 7-265431 disclose that an embolizing material such as a coil can be attached to the distal end of a guide wire by an appropriate cuttable connecting member.
- a method has been proposed in which the embolic material is detached from a guide wire by placing the embolic material in a required place and cutting the connecting member after the embolic material is placed at a required location, and placing the embolic material in an aneurysm, for example. .
- the connecting member in order to release the embolic material, is formed of stainless steel and is melted by electrolysis by the current of the positive electrode, or the connecting member is formed of polyvinyl alcohol. Means for fusing this with a high frequency current are used.
- embolic material when embolic material is to be placed in a lesion such as an aneurysm, a micro force catheter is first introduced into the aneurysm, and embolic material such as a coil is fed through the microcatheter with a placement wire. Filling the aneurysm with embolic material is performed. If one embolic material cannot sufficiently fill the aneurysm, two or more embolic materials are sequentially inserted.
- the embolic material to be disposed is of a specific length selected by prediction from various conditions, and in fact, the embolic material is The entire aneurysm cannot be inserted into the aneurysm, and the aneurysm may become full at the stage when it is inserted halfway. In this case, forcibly pushing the rest of the embolic material into the aneurysm must be avoided because it may cause rupture of the aneurysm. It can cause thrombosis if left in the (artery). Therefore, it is necessary to pull back the embolic material, change the embolic material to an appropriate length, and re-arrange the material.
- the embolic material may be entangled with the already placed embolic material, or the coil shape of the embolic material may be deformed. It can be impossible Disclosure of the invention
- the length or the amount of the placed indwelling member in the living body cannot be changed after being inserted into the living body.
- the intended placement of the indwelling member cannot be easily performed.
- an object of the present invention is to provide a medical device for placing an in-vivo indwelling member that can perform a cutting operation via a catheter, and a method of arranging an in-vivo indwelling member using the same.
- the in-vivo indwelling member placement medical device of the present invention includes a catheter having an electrode at a distal end portion, which is inserted into a living body, and a in-vivo indwelling member placement wire device guided by the catheter.
- the in-vivo indwelling member arranging wire device is composed of one or two in-vivo indwelling elements, which are connected to the in-vivo indwelling member arranging wire by a first connecting member that can be cut at the distal end of the wire.
- An in-vivo indwelling member configured to be sequentially connected via the severable second connecting member,
- the in-vivo indwelling member of the in-vivo indwelling-member arranging wire guide device guided through the catheter is protruded from the distal end of the catheter, the in-vivo The first connecting member or the second connecting member of the indwelling member arranging wire device is cut off.
- the first connection member or the second connection member be blown at the distal end of the catheter by supplying a high-frequency current to the electrode of the catheter.
- the in-vivo indwelling element of the in-vivo indwelling member can be formed by a biocompatible metal coil.
- first connecting member and the second connecting member connecting member can be formed of a heat-fusible material, for example, a polyvinyl alcohol-based polymer.
- the in-vivo indwelling element positioned at the foremost side has the longest length
- the first connecting member and the second connecting member may be formed of a body common connecting material.
- the in-vivo indwelling element may have a structure provided with a fibrous body for promoting thrombus formation, and the in-vivo indwelling element may have a shape memory characteristic.
- the method for arranging an in-vivo indwelling member of the present invention includes the steps of: inserting a catheter having an electrode at a distal end into a living body, and positioning the distal end at a target location where the in-vivo indwelling member is to be arranged;
- the in-vivo indwelling member arranging wire and a second in-vivo indwelling element that can be cut by one or two or more in-vivo indwelling elements that are connected to the distal end of the wire by a first connecting member that can be cut.
- the in-vivo indwelling member arranging wire device including the in-vivo indwelling member having a configuration sequentially connected via the catheter is guided through the catheter, and the in-vivo indwelling member is projected from the tip of the catheter. Supplying power to the electrode of the catheter, thereby cutting the first connecting member or the second connecting member of the in-vivo indwelling member placement wire device.
- the invention is characterized in that all or a part of the indwelling element is placed at the target location.
- the operation of cutting the first connecting member or the second connecting member is performed by a monobora high-frequency wave between the electrode of the catheter and the counter electrode serving as a ground electrode installed on the surface of the living body. It is preferably performed by supplying a current.
- the in-vivo indwelling member arranging wire device is inserted into the living body via the catheter, and the in-vivo indwelling member is placed at a target location such as an aneurysm.
- the in-vivo indwelling member and the placement wire are connected by a first connecting member, and a plurality of in-vivo indwelling elements constituting the in-vivo indwelling member are included in one or more of Since the connection members are connected by the connection member (2), even these connection members can be cut by supplying power to the electrode of the catheter, so the connection member to be cut is selected. By doing so, it is possible to change or adjust the length or amount of the indwelling member that is actually separated and placed. Therefore, an indwelling member of an appropriate length or amount in a living body can be extremely easily arranged at a target location.
- FIG. 1 is an explanatory perspective view showing the overall configuration of a wire device in an example of the medical device for placing an indwelling member in a living body of the present invention.
- FIG. 2 is an enlarged view showing a composite coil body constituting the in-vivo indwelling member of FIG. 1 and a connection state thereof.
- FIG. 3 is an explanatory view showing a state where the composite coil body of FIG. 2 is extended.
- FIG. 4 is an explanatory sectional view of FIG.
- FIG. 5 is an explanatory sectional view showing another example of the composite coil body.
- FIG. 6 is an explanatory sectional view showing still another example of the composite coil body.
- FIG. 7 is an explanatory front view showing a configuration of a micro force table used for inserting a wire device into a living body.
- FIG. 8 is an explanatory cross-sectional view showing another example of the composite coil body.
- FIG. 1 is an explanatory perspective view showing an entire configuration of a wire device in an example of a medical device for placing an indwelling member in a living body according to the present invention.
- FIG. 2 is a composite coil body constituting the indwelling member in FIG.
- FIG. 3 is an explanatory view showing a state where the composite coil body of FIG. 2 is linearly extended
- FIG. 4 is a sectional view for explanation of FIG.
- the wire device 10 is a composite wire comprising a placement wire 12 used as a pusher, a connection coil member 13, a first connection member 15, and a living body indwelling member. And a coil body 16.
- the placement wire 12 is made of, for example, stainless steel and has a proximal portion 12 A on the right side of the figure and a flexible taper portion 12 whose outer diameter decreases toward the distal end (left side of the figure).
- B of the connecting coil member 13 having a small-diameter portion 13 A made of, for example, stainless steel and a large-diameter portion 13 B at the tip end following the tapered portion 12 B. The proximal end of the small diameter portion 13 A is fitted.
- the arranging wire 12 may have a configuration in which, for example, a wound wire is densely wound in a coil shape on the outer peripheral surface of the core wire.
- the outer diameter of the arranging wire 12 is preferably from 0.1 to 2.0 mm, but the length may be various lengths depending on the purpose, for example, in the range of 100 to 200 mm. It is.
- the base end of the first connecting member 15 made of a short rod-shaped polyvinyl alcohol-based polymer is inserted and adhered with an adhesive. And the front end of the first connecting member 15 is inserted into the base end of the first coil element 16A of the composite coil body 16 and is connected by an adhesive.
- the wire 12 and the composite coil body 16 are integrally connected via the first connecting member 15.
- the composite coil body 16 constituting the in-vivo indwelling member is composed of a plurality (four in the example shown) of coil elements 16A to 16D, each of which is composed of a short rod-shaped polyvial alcohol-based polymer in total.
- the second connection members 17A to 17C are sequentially connected in series, and the specific connection mode is, as shown in FIG. 4, the end of the second connection member being a coil related to the connection. This has been achieved by being inserted into the end of the element and then bonded and fixed with an adhesive.
- Reference numeral 18 denotes a hemispherical portion having a smooth surface formed at the tip of the leading coil element 16D, and is formed by, for example, heat-melting a wire of the coil element.
- Reference numeral 20 denotes a bonding portion formed by an adhesive.
- Each of the coil elements 16A to 16D constituting the composite coil body 16 is formed of a biocompatible metal coil.
- a material selected from platinum, tungsten, tantalum, gold, palladium, rhodium, titanium and an alloy thereof is used as a specific material of the coil element 16A to 16D. Alloys with tungsten are preferred. Since the coil element made of such a material is opaque to X-rays, it can be visually recognized in a contrasted manner.
- Each of the illustrated coil elements 16A to 16D has a double coil shape in its natural form.
- the length L in the primary coil state (see FIG. 3) is approximately 1 in the secondary coil. It is a turn, but is not limited to this.
- Each of the second connecting members 17A to 17C constituting the composite coil body 16 is formed of the same material as that of the first connecting member 15, and may have the same length and shape. . These connecting members have an appropriate length, and in the connected state, a part of the outer peripheral surface of the connecting member is exposed.
- the range of dimensions of the composite coil body 16 is as follows.
- the diameter of each wire of the coil elements 16 A to 16 D is 0.01 to 0.10 mm
- the outer diameter of the primary coil is 0.1 to 1.0 mm
- the outer diameter of the secondary coil is 1.0 to 20 0 mm.
- each of the first connecting member 15 and the second connecting members 17A to 17C Is set to a size suitable for the inner diameter of the primary coil of the coil element, and its length may be long enough for connection, but the length E of the exposed part is set to 0.5 to 2.0 mm. Preferably.
- the material of the connecting member does not adversely affect the living body, and can be cut arbitrarily after being inserted into the living body. It is not particularly limited as long as it can be obtained, but is preferably cut by energizing an electrode of a microcatheter described later, and is preferably cut by heating.
- a material that melts by heating with a high-frequency current for example, a polyvinyl alcohol-based polymer is more preferable.
- the mode of connection by the connecting member is not particularly limited, and for example, bonding by an adhesive, welding, connection by physical force, and other means can be used. Of these, adhesive bonding is particularly preferred. In this case, for example, a cyanoacrylate-based adhesive can be suitably used as the adhesive.
- the number of coil elements, the length and form of each coil element are not particularly limited and can be freely determined, and the coil elements having different lengths and forms are connected to form a composite coil body. Can also be configured.
- the coil element (17 A) connected by the first connecting member 15 has the shortest length, and the first coil element has the longest length.
- the intermediate coil elements can be connected so as to become longer sequentially. According to such a configuration, the length of the in-vivo indwelling element to be inserted and arranged later is gradually shortened, so that there is an advantage that the degree of freedom in actual use is increased.
- FIG. 5 is an explanatory cross-sectional view showing another example of the composite coil body 16.
- the first connecting member 15 and the second connecting members 17A to 17 in the example of FIG. All of C are formed by a common connecting material 25 consisting of one rod.
- FIG. 6 is an explanatory cross-sectional view showing still another example of the composite coil body 16.
- formation of a thrombus is performed on each of the coil elements 16A to 16D in the example of FIG.
- the fiber body 28 to be promoted is provided so as to protrude radially outward with a length of about 1 to 1 O mm.
- the fibrous body 28 is made of, for example, polyester, fluororesin, or nylon. It can be provided by sandwiching between adjacent ones of the ring-shaped wires constituting the primary coil in each of the coil elements 16A to 16D, for example.
- FIG. 7 is an explanatory front view showing a configuration of a micro catheter that is advantageously used for inserting the above-described wire device 10 into a living body.
- the microcatheter 30 of this example includes a catheter body 31, a hand operation section 32 provided at a hand end of the catheter body 31, and a hand side embedded in a wall of the catheter body 31. And a ring-shaped electrode 35 provided at the distal end of the catheter body 31. The electrode 35 is electrically connected to the blade 33. It is connected.
- Reference numeral 38 denotes a high-frequency wave electrically connected to the proximal side of the blade 33.
- FIG. 8 shows a microcatheter 30 similar to that of FIG. 7, but in this example, instead of the blade 33, a metal wire lead 34 extending from the proximal side of the force sensor body 31 to the distal end is used. Is provided, whereby the high-frequency power supply 38 and the electrode 35 are electrically connected.
- the in-vivo indwelling member is arranged at an intended position in the living body as follows. You.
- the microcatheter 30 is inserted into a living body by an ordinary technique, and the opening at the distal end thereof is made to face a target location where the in-vivo indwelling member is to be placed, for example, an opening of an aneurysm.
- the wire device 10 is inserted into the micro-catheter 30 via the hand operation unit 32 with the composite coil body 16 at the top, and further pushed into the micro-catheter 30. At this time, the composite coil body 16 moves in the catheter body 31 with the secondary coils of the coil elements 16A to 16D extending substantially linearly along the catheter body 31.
- the secondary core After memorizing the shape of the coil, it is inserted into the catheter body 31 as a straight line (as shown in Fig. 3 in the state of the primary coil with the secondary coil unraveled), pushed in, and then returned to its original shape It can also be done.
- a composite coil body 16 as an indwelling member is protruded from the distal end opening of the catheter body 31 by an appropriate length to the outside, and the protruded portion of the composite coil body is disposed at an application location such as an aneurysm. I do. Then, with the necessary length or amount of the composite coil body being arranged, the high-frequency power supply 38 was used to separately set the electrode 35 at the tip of the catheter body 31 and the surface of the living body separately. A monopolar high-frequency current is supplied between the ground electrode and the counter electrode. This high-frequency current is supplied to the electrode 35 by the blade 33 in the micro force catheter 30 of FIG. 7, and by the metal wire lead 34 in the example of FIG.
- the projected state of the composite coil body 16 from the microcatheter 30 can be known with a certain degree of accuracy from the contrast image of the X-ray opaque coil element of the wire device 10.
- the electrodes 35 are exposed on the inner peripheral surface of the distal end portion of the catheter body 31 so that the coil elements 16 A to 16 D of the composite coil body 16 of the wire device 10 passing therethrough are formed.
- the wire connection is performed.
- the electric resistance value is determined by the coil element 16 D at the top of the composite coil body 16 and the opening of the catheter body 31.
- the electric resistance value is greatly reduced. Then, such an electric resistance value decreases, and then increases repeatedly. By monitoring the decrease or increase in the electric resistance value, it is possible to accurately detect which part of the composite coil body 16 projects from the catheter body 31. can do.
- the supply of the high-frequency current described above causes the catheter body 31 to protrude from the distal opening.
- Connecting member closest to the electrode 35 (in the example shown, one of the first connecting member 15 or the second connecting member 17A to 17C) Force High frequency current
- the connecting member is cut off by the heating action of the connecting member, and as a result, the portion of the composite coil body 16 on the leading side of the cut connecting member, that is, one or more separated coil elements and
- the connecting member or the rest thereof is arranged as an actual living body indwelling member.
- the composite coil body 16 of the above-described wire device 10 all of the first connecting member 15 and the second connecting members 17 A to 17 C are cut by fusing. Since the connecting member can be obtained, by selecting the connecting member to be cut, the length or amount of the actually placed living body and indwelling member can be changed or adjusted very easily. A very appropriate length or amount of the indwelling member in a living body can be easily arranged in a short time.
- the connecting member is made of a polyvinyl alcohol-based polymer, and the connecting member can be blown off by supplying a high-frequency current for a very short time of 1 to 3 seconds or less.
- the in-vivo indwelling member is not limited to the composite coil body, but may be in any other form, for example, an appropriate in-vivo indwelling element such as a ring, a pipe, or a capsule. What is necessary is that the indwelling elements can be connected to each other and can be cut arbitrarily. In practice, it is preferable to use an electrode provided at the distal end of the catheter for guiding the wire device, and to cut the wire by energization.
- the electrode 35 at the tip of the force sensor body may be constituted by a single electrode body. It is preferable because it is possible.
- a pair of electrode bodies are arranged at the distal end of the catheter body at a distance from each other, and each of them is energized via a lead wire to heat and cut the connecting member at the position between the two electrodes. Can also. In this case, it is, of course, unnecessary to provide the living body with a counter electrode.
- the tip of a placement wire (12) having a length of 180 Omm and a diameter of 016 mm is connected to a tip of a polyvinyl alcohol copolymer 0.2 mm through a coupling coil member (13).
- One end of a cylindrical rod-shaped first connecting member (15) having a length of 10 mm was connected.
- the ends were connected such that the length of the exposed portion of the first connecting member (the separation distance E between the first coil element and the connecting coil member) was 1 mm.
- the second coil element 16B is connected to the first coil element using the same second connection member (17A) as the first connection member in the same manner as the connection by the first connection member.
- a composite coil body (16) in which five coil elements are connected by a total of four second connection members is connected to an arrangement key by the first connection member.
- a wire device (10) was fabricated.
- Eight stainless steel wires are arranged so that they extend right-hand spirally from one end to the other, and one similar stainless steel wire has one counter-clockwise spiral.
- a catheter body with an inner diameter of 0.55 mm and an outer diameter of 0.95 mm is embedded with a braid (33) that is arranged so that it extends in the tube.
- the electrode (31) was prepared, and a platinum ring having an outer diameter of 0.8 mm, an inner diameter of 0.6 mm, and a width of 0.5 mm was exposed and provided on the peripheral surface of one end of the catheter body.
- Blur The electrode (35) is electrically connected to the blade, and a current-carrying terminal electrically connected to the blade is provided at the other end of the catheter body. 30) was prepared.
- a microcatheter was introduced from the femoral artery of the adult dog into the carotid artery, and the wire device was inserted and pushed into the microcatheter with the composite coil at the top. Then, by utilizing the fact that the coil element (16) of the composite coil body passes while contacting the electrode (35) of the force catheter body (31), the coil element is attached to the electrode and the back of the adult dog.
- the wire device was continuously pushed in while monitoring the electrical resistance between the counter electrode and the electrode, the electrical resistance repeatedly decreased and increased. This is because the electrical resistance decreases when the leading coil element of the composite coil body protrudes from the opening of the catheter body, and the electrical resistance increases when the connecting member is positioned at the opening of the catheter body. Because it is repeated.
- the living body indwelling member in the in-vivo indwelling member arranging wire device can cut a plurality of portions including the connecting portion between the in-vivo indwelling member and the arranging wire. Because of the connecting point, the length or amount of the part of the in-vivo indwelling member that is actually cut off is selected or selected by selecting the connecting member to be cut while the wire device is inserted. Therefore, even when the conditions of the actual placement location are different from those expected, a very appropriate length or amount of the indwelling member in a living body can be placed and placed. The invention's effect
- the length or amount of an in-vivo indwelling member to be actually placed can be changed or adjusted even in a state in which a wire device is inserted, and therefore, extremely suitable An in-vivo indwelling member of an appropriate length or amount can be arranged and indwelled.
- the time required for the operation of placing the indwelling member in the living body can be extremely short, and the mental and physical burdens on doctors and patients can be greatly reduced, Easy operation and high reliability.
Description
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/331,269 US6159206A (en) | 1997-10-30 | 1998-10-29 | Medical implement for depositing implanted device and method of depositing implanted device |
EP98950439A EP0948935B1 (en) | 1997-10-30 | 1998-10-29 | Medical implement for depositing implantable device |
JP52152599A JP4130234B2 (ja) | 1997-10-30 | 1998-10-29 | 生体内留置部材配置用医療用具 |
DE69838375T DE69838375T2 (de) | 1997-10-30 | 1998-10-29 | Medizinische vorrichtung zum einbringen eines implantierbaren gegenstands |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9/298889 | 1997-10-30 | ||
JP29888997 | 1997-10-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999022651A1 true WO1999022651A1 (fr) | 1999-05-14 |
Family
ID=17865483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP1998/004894 WO1999022651A1 (fr) | 1997-10-30 | 1998-10-29 | Dispositif medical pour placer un element in vivo a demeure et methode de placement de cet element |
Country Status (5)
Country | Link |
---|---|
US (1) | US6159206A (ja) |
EP (1) | EP0948935B1 (ja) |
JP (1) | JP4130234B2 (ja) |
DE (1) | DE69838375T2 (ja) |
WO (1) | WO1999022651A1 (ja) |
Cited By (6)
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JP2003508107A (ja) * | 1999-08-31 | 2003-03-04 | マイクロ・セラピューティクス・インコーポレーテッド | 液体塞栓組成物の注入制御装置 |
WO2007118005A1 (en) * | 2006-03-30 | 2007-10-18 | Boston Scientific Limited | Implantable medical endoprosthesis delivery system |
JP2010500915A (ja) * | 2006-08-17 | 2010-01-14 | エヌフォーカス ニューロメディカル, インコーポレイテッド | 動脈瘤の治療用隔離デバイス |
US9486608B2 (en) | 2008-08-19 | 2016-11-08 | Covidien Lp | Detachable tip microcatheter |
US10124087B2 (en) | 2012-06-19 | 2018-11-13 | Covidien Lp | Detachable coupling for catheter |
EP3565494A4 (en) * | 2017-01-07 | 2020-12-09 | Balt USA | IMPROVED THERMAL VALVE ARRANGEMENT |
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DE69939685D1 (de) * | 1998-12-01 | 2008-11-20 | Univ Washington | Vorrichtung zur intravaskulären embolisierung |
US6221066B1 (en) * | 1999-03-09 | 2001-04-24 | Micrus Corporation | Shape memory segmented detachable coil |
EP2319455A3 (en) | 1999-06-02 | 2012-04-18 | Microtransform, Inc. | Intracorporeal occlusive device |
WO2001054761A2 (en) * | 2000-01-28 | 2001-08-02 | William Cook, Europe Aps | Endovascular medical device with plurality of wires |
US6589265B1 (en) * | 2000-10-31 | 2003-07-08 | Endovascular Technologies, Inc. | Intrasaccular embolic device |
US6743251B1 (en) * | 2000-11-15 | 2004-06-01 | Scimed Life Systems, Inc. | Implantable devices with polymeric detachment junction |
US8721625B2 (en) * | 2001-01-26 | 2014-05-13 | Cook Medical Technologies Llc | Endovascular medical device with plurality of wires |
US6692510B2 (en) * | 2001-06-14 | 2004-02-17 | Cordis Neurovascular, Inc. | Aneurysm embolization device and deployment system |
EP1793744B1 (de) | 2004-09-22 | 2008-12-17 | Dendron GmbH | Medizinisches implantat |
DE502004010411D1 (de) | 2004-09-22 | 2009-12-31 | Dendron Gmbh | Vorrichtung zur implantation von mikrowendeln |
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Also Published As
Publication number | Publication date |
---|---|
JP4130234B2 (ja) | 2008-08-06 |
EP0948935B1 (en) | 2007-09-05 |
DE69838375D1 (de) | 2007-10-18 |
EP0948935A4 (en) | 2002-01-16 |
EP0948935A1 (en) | 1999-10-13 |
DE69838375T2 (de) | 2008-01-17 |
US6159206A (en) | 2000-12-12 |
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