WO1999037205A1 - Method and device for tissue modulation - Google Patents
Method and device for tissue modulation Download PDFInfo
- Publication number
- WO1999037205A1 WO1999037205A1 PCT/US1999/001704 US9901704W WO9937205A1 WO 1999037205 A1 WO1999037205 A1 WO 1999037205A1 US 9901704 W US9901704 W US 9901704W WO 9937205 A1 WO9937205 A1 WO 9937205A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tissue
- blood
- region
- raised
- recessed
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 39
- 210000004369 blood Anatomy 0.000 claims abstract description 88
- 239000008280 blood Substances 0.000 claims abstract description 88
- 238000005259 measurement Methods 0.000 claims abstract description 39
- 238000001228 spectrum Methods 0.000 claims abstract description 19
- 239000012491 analyte Substances 0.000 claims abstract description 18
- 230000005670 electromagnetic radiation Effects 0.000 claims abstract description 9
- 230000001678 irradiating effect Effects 0.000 claims abstract description 9
- 230000003287 optical effect Effects 0.000 claims description 11
- 238000001237 Raman spectrum Methods 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 6
- 230000005284 excitation Effects 0.000 claims description 6
- 239000000835 fiber Substances 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 description 130
- 210000003491 skin Anatomy 0.000 description 11
- 230000017531 blood circulation Effects 0.000 description 9
- 210000003811 finger Anatomy 0.000 description 9
- 230000002123 temporal effect Effects 0.000 description 6
- 230000003068 static effect Effects 0.000 description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 230000003321 amplification Effects 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 238000010606 normalization Methods 0.000 description 4
- 238000003199 nucleic acid amplification method Methods 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 238000005481 NMR spectroscopy Methods 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 230000003595 spectral effect Effects 0.000 description 3
- 238000004435 EPR spectroscopy Methods 0.000 description 2
- 241000124008 Mammalia Species 0.000 description 2
- 238000001069 Raman spectroscopy Methods 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 210000000481 breast Anatomy 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 230000002596 correlated effect Effects 0.000 description 2
- 230000000875 corresponding effect Effects 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 238000002189 fluorescence spectrum Methods 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 238000001296 phosphorescence spectrum Methods 0.000 description 2
- 230000010287 polarization Effects 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000004611 spectroscopical analysis Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 241000282465 Canis Species 0.000 description 1
- 241000283073 Equus caballus Species 0.000 description 1
- 241000282324 Felis Species 0.000 description 1
- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- 241000270322 Lepidosauria Species 0.000 description 1
- 241001529936 Murinae Species 0.000 description 1
- 206010047139 Vasoconstriction Diseases 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 238000004847 absorption spectroscopy Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000004159 blood analysis Methods 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 210000000624 ear auricle Anatomy 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000002095 near-infrared Raman spectroscopy Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000002496 oximetry Methods 0.000 description 1
- 230000010363 phase shift Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 231100000430 skin reaction Toxicity 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 230000005945 translocation Effects 0.000 description 1
- 230000025033 vasoconstriction Effects 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
- 238000002460 vibrational spectroscopy Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
- A61B5/0053—Detecting, measuring or recording by applying mechanical forces or stimuli by applying pressure, e.g. compression, indentation, palpation, grasping, gauging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
- A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
- A61B5/02427—Details of sensor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69920170T DE69920170T2 (en) | 1998-01-27 | 1999-01-27 | DEVICE AND METHOD FOR MODULATING TISSUE |
AT99904315T ATE275867T1 (en) | 1998-01-27 | 1999-01-27 | DEVICE AND METHOD FOR MODULATING TISSUE |
JP2000528203A JP2002500908A (en) | 1998-01-27 | 1999-01-27 | Tissue modulation apparatus and method |
AU24736/99A AU2473699A (en) | 1998-01-27 | 1999-01-27 | Method and device for tissue modulation |
CA002315192A CA2315192C (en) | 1998-01-27 | 1999-01-27 | Method and device for tissue modulation |
EP99904315A EP1051106B1 (en) | 1998-01-27 | 1999-01-27 | Method and device for tissue modulation |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7271098P | 1998-01-27 | 1998-01-27 | |
US7265898P | 1998-01-27 | 1998-01-27 | |
US60/072,658 | 1998-01-27 | ||
US60/072,710 | 1998-01-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999037205A1 true WO1999037205A1 (en) | 1999-07-29 |
WO1999037205A8 WO1999037205A8 (en) | 1999-09-02 |
Family
ID=26753603
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/001704 WO1999037205A1 (en) | 1998-01-27 | 1999-01-27 | Method and device for tissue modulation |
Country Status (9)
Country | Link |
---|---|
US (1) | US6223063B1 (en) |
EP (1) | EP1051106B1 (en) |
JP (1) | JP2002500908A (en) |
AT (1) | ATE275867T1 (en) |
AU (1) | AU2473699A (en) |
CA (1) | CA2315192C (en) |
DE (1) | DE69920170T2 (en) |
ES (1) | ES2224602T3 (en) |
WO (1) | WO1999037205A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002003857A2 (en) * | 2000-07-11 | 2002-01-17 | Lightouch Medical, Inc. | Method of tissue modulation for noninvasive measurement of an analyte |
JP2004504905A (en) * | 2000-08-02 | 2004-02-19 | センシス メディカル インク | Apparatus and method for reproducibly correcting local absorption and scattering coefficients at a tissue measurement site during optical sampling |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8174394B2 (en) * | 2001-04-11 | 2012-05-08 | Trutouch Technologies, Inc. | System for noninvasive determination of analytes in tissue |
US8581697B2 (en) * | 2001-04-11 | 2013-11-12 | Trutouch Technologies Inc. | Apparatuses for noninvasive determination of in vivo alcohol concentration using raman spectroscopy |
US7616123B2 (en) * | 2001-04-11 | 2009-11-10 | Trutouch Technologies, Inc. | Apparatus and method for noninvasively monitoring for the presence of alcohol or substances of abuse in controlled environments |
US6697658B2 (en) | 2001-07-02 | 2004-02-24 | Masimo Corporation | Low power pulse oximeter |
US20120078075A1 (en) * | 2002-04-04 | 2012-03-29 | Maynard John D | Determination of a measure of a glycation end-product or disease state using tissue fluorescence in combination with one or more other tests |
US8175666B2 (en) * | 2002-04-26 | 2012-05-08 | Grove Instruments, Inc. | Three diode optical bridge system |
US7003337B2 (en) * | 2002-04-26 | 2006-02-21 | Vivascan Corporation | Non-invasive substance concentration measurement using and optical bridge |
US6925322B2 (en) * | 2002-07-25 | 2005-08-02 | Biophan Technologies, Inc. | Optical MRI catheter system |
EP1549165B8 (en) | 2002-10-01 | 2010-10-06 | Nellcor Puritan Bennett LLC | Use of a headband to indicate tension and system comprising an oximetry sensor and a headband |
US7698909B2 (en) | 2002-10-01 | 2010-04-20 | Nellcor Puritan Bennett Llc | Headband with tension indicator |
US7613488B1 (en) * | 2002-12-20 | 2009-11-03 | Niresults Inc. | Apparatus and methods for compensation of blood volume effects on NIR spectroscopic measurements of blood analytes |
US6943892B2 (en) * | 2003-01-29 | 2005-09-13 | Sarnoff Corporation | Instrument having a multi-mode optical element and method |
US6836597B2 (en) * | 2003-01-29 | 2004-12-28 | Sarnoff Corporation | Scannable mirror arrangement for an interferometer |
US7047056B2 (en) | 2003-06-25 | 2006-05-16 | Nellcor Puritan Bennett Incorporated | Hat-based oximeter sensor |
US8412297B2 (en) | 2003-10-01 | 2013-04-02 | Covidien Lp | Forehead sensor placement |
JP4047903B2 (en) * | 2004-03-29 | 2008-02-13 | 松下電器産業株式会社 | Biological information measuring optical element and biological information measuring apparatus using the same |
US20080319286A1 (en) * | 2004-05-24 | 2008-12-25 | Trent Ridder | Optical Probes for Non-Invasive Analyte Measurements |
US8515506B2 (en) * | 2004-05-24 | 2013-08-20 | Trutouch Technologies, Inc. | Methods for noninvasive determination of in vivo alcohol concentration using Raman spectroscopy |
US20110178420A1 (en) * | 2010-01-18 | 2011-07-21 | Trent Ridder | Methods and apparatuses for improving breath alcohol testing |
US8730047B2 (en) | 2004-05-24 | 2014-05-20 | Trutouch Technologies, Inc. | System for noninvasive determination of analytes in tissue |
US20060063991A1 (en) * | 2004-08-09 | 2006-03-23 | Dejin Yu | Method and apparatus for non-invasive measurement of blood analytes with dynamic spectral calibration |
US20060063992A1 (en) * | 2004-08-09 | 2006-03-23 | Dejin Yu | Method and apparatus for non-invasive measurement of blood analytes |
US20060063993A1 (en) * | 2004-08-09 | 2006-03-23 | Dejin Yu | Method and apparatus for non-invasive measurement of blood analytes |
GB0426993D0 (en) * | 2004-12-09 | 2005-01-12 | Council Cent Lab Res Councils | Apparatus for depth-selective raman spectroscopy |
WO2006074337A1 (en) * | 2005-01-06 | 2006-07-13 | Lightouch Medical, Inc. | Specialized human servo device and process for tissue modulation of human fingertips |
EP1860995A1 (en) | 2005-03-01 | 2007-12-05 | Masimo Laboratories, Inc. | Multiple wavelength sensor substrate |
US20060211926A1 (en) * | 2005-03-21 | 2006-09-21 | Dejin Yu | Non-invasive Raman measurement apparatus with broadband spectral correction |
JP5001934B2 (en) * | 2005-04-15 | 2012-08-15 | バイエル・ヘルスケア・エルエルシー | Non-invasive system and method for measuring body glucose |
US8452365B2 (en) * | 2005-05-25 | 2013-05-28 | Bayer Healthcare Llc | Methods of using Raman spectral information in determining analyte concentrations |
WO2008024276A2 (en) * | 2006-08-22 | 2008-02-28 | Bayer Healthcare Llc | A method for correcting a spectral image for optical aberrations using software |
US7603151B2 (en) * | 2006-08-22 | 2009-10-13 | Bayer Healthcare Llc | Non-invasive methods of using spectral information in determining analyte concentrations |
CN102015020A (en) * | 2008-05-09 | 2011-04-13 | 休·贝克曼 | Medical device for diagnosing and treating anomalous tissue and method for doing the same |
US8260402B2 (en) * | 2008-06-06 | 2012-09-04 | Longevity Link, Inc. | Noninvasive measurement of carotenoids in biological tissue |
US20100030040A1 (en) | 2008-08-04 | 2010-02-04 | Masimo Laboratories, Inc. | Multi-stream data collection system for noninvasive measurement of blood constituents |
US8577431B2 (en) * | 2008-07-03 | 2013-11-05 | Cercacor Laboratories, Inc. | Noise shielding for a noninvasive device |
US8257274B2 (en) | 2008-09-25 | 2012-09-04 | Nellcor Puritan Bennett Llc | Medical sensor and technique for using the same |
US8364220B2 (en) | 2008-09-25 | 2013-01-29 | Covidien Lp | Medical sensor and technique for using the same |
US20100113899A1 (en) * | 2008-11-06 | 2010-05-06 | Mark Ries Robinson | Alignment System for Optically Sampling a Hand |
US8515515B2 (en) | 2009-03-25 | 2013-08-20 | Covidien Lp | Medical sensor with compressible light barrier and technique for using the same |
US8781548B2 (en) | 2009-03-31 | 2014-07-15 | Covidien Lp | Medical sensor with flexible components and technique for using the same |
US8688183B2 (en) | 2009-09-03 | 2014-04-01 | Ceracor Laboratories, Inc. | Emitter driver for noninvasive patient monitor |
US8538499B2 (en) * | 2009-09-23 | 2013-09-17 | Lightouch Medical, Inc. | Process and apparatus for non-invasive, continuous in vivo measurement of hematocrit |
US9603559B2 (en) * | 2009-12-24 | 2017-03-28 | Children's Medical Center Corporation | Capillary refill time diagnostic apparatus and methods |
US9662047B2 (en) | 2010-08-05 | 2017-05-30 | Massachusetts Institute Of Technology | Portable raman diagnostic system |
BR112015019505B1 (en) * | 2013-02-13 | 2022-02-08 | Leman Micro Devices Sa | PERSONAL PORTABLE MONITOR FOR NON-INVASIVE BLOOD ANALYSIS |
US10646143B2 (en) * | 2013-03-08 | 2020-05-12 | Alethus, Inc. | Optically discriminative detection of matters in tissues and turbid media and applications for non-invasive assay |
EP3013217B1 (en) | 2014-01-07 | 2017-02-22 | Opsolution GmbH | Device and method for determining a concentration in a sample |
US20160206231A1 (en) * | 2015-01-21 | 2016-07-21 | Grove Instruments, Inc. | Noninvasive measurement of analyte concentration using methods and systems of post-balancing |
EP3087916B1 (en) * | 2015-04-28 | 2023-09-20 | Nokia Technologies Oy | Physiological measurement sensor |
US10448871B2 (en) | 2015-07-02 | 2019-10-22 | Masimo Corporation | Advanced pulse oximetry sensor |
US10638960B2 (en) * | 2015-10-26 | 2020-05-05 | Reveal Biosensors, Inc. | Optical physiologic sensor methods |
KR101736997B1 (en) * | 2016-01-04 | 2017-05-29 | 현대자동차주식회사 | Wrist-worn apparatus for detecting biosignal |
GB201608781D0 (en) * | 2016-05-19 | 2016-07-06 | Leman Micro Devices Sa | Non-invasive blood analysis |
KR102574086B1 (en) | 2018-02-21 | 2023-09-04 | 삼성전자주식회사 | Raman probe |
KR20200092665A (en) * | 2019-01-25 | 2020-08-04 | 삼성전자주식회사 | Texture interface for measuring biological signal and biological signal measurement apparatus comprising the same |
KR20210022319A (en) * | 2019-08-20 | 2021-03-03 | 삼성전자주식회사 | Apparatus and method for estimating bio-information |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1909882A1 (en) * | 1969-02-27 | 1970-09-17 | Battelle Institut E V | Device for measuring body functions in humans and animals by measuring the optical reflection properties of the tissue with alternating blood supply and processes for their production |
WO1993000856A1 (en) * | 1991-07-03 | 1993-01-21 | Vivascan Corporation | A non-invasive method and apparatus for measuring concentration of analytes in living tissue |
WO1993012712A1 (en) * | 1991-12-31 | 1993-07-08 | Vivascan Corporation | Blood constituent determination based on differential spectral analysis |
EP0573137A2 (en) * | 1992-06-03 | 1993-12-08 | Alza Corporation | Methods and devices for facilitated non-invasive oxygen monitoring |
WO1994010901A1 (en) * | 1992-11-09 | 1994-05-26 | Boehringer Mannheim Gmbh | Process and device for glucose determination in a biological matrix |
US5553616A (en) | 1993-11-30 | 1996-09-10 | Florida Institute Of Technology | Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discriminator |
US5615673A (en) | 1995-03-27 | 1997-04-01 | Massachusetts Institute Of Technology | Apparatus and methods of raman spectroscopy for analysis of blood gases and analytes |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5099842A (en) * | 1988-10-28 | 1992-03-31 | Nellcor Incorporated | Perinatal pulse oximetry probe |
US5313940A (en) * | 1991-05-15 | 1994-05-24 | Nihon Kohden Corporation | Photo-electric pulse wave measuring probe |
US6088540A (en) * | 1997-09-17 | 2000-07-11 | Eastman Kodak Company | Camera flash unit including a condenser lens element with a TIR surface |
-
1999
- 1999-01-27 DE DE69920170T patent/DE69920170T2/en not_active Expired - Lifetime
- 1999-01-27 EP EP99904315A patent/EP1051106B1/en not_active Expired - Lifetime
- 1999-01-27 JP JP2000528203A patent/JP2002500908A/en active Pending
- 1999-01-27 ES ES99904315T patent/ES2224602T3/en not_active Expired - Lifetime
- 1999-01-27 US US09/238,487 patent/US6223063B1/en not_active Expired - Lifetime
- 1999-01-27 CA CA002315192A patent/CA2315192C/en not_active Expired - Fee Related
- 1999-01-27 WO PCT/US1999/001704 patent/WO1999037205A1/en active IP Right Grant
- 1999-01-27 AT AT99904315T patent/ATE275867T1/en not_active IP Right Cessation
- 1999-01-27 AU AU24736/99A patent/AU2473699A/en not_active Abandoned
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1909882A1 (en) * | 1969-02-27 | 1970-09-17 | Battelle Institut E V | Device for measuring body functions in humans and animals by measuring the optical reflection properties of the tissue with alternating blood supply and processes for their production |
WO1993000856A1 (en) * | 1991-07-03 | 1993-01-21 | Vivascan Corporation | A non-invasive method and apparatus for measuring concentration of analytes in living tissue |
WO1993012712A1 (en) * | 1991-12-31 | 1993-07-08 | Vivascan Corporation | Blood constituent determination based on differential spectral analysis |
EP0573137A2 (en) * | 1992-06-03 | 1993-12-08 | Alza Corporation | Methods and devices for facilitated non-invasive oxygen monitoring |
WO1994010901A1 (en) * | 1992-11-09 | 1994-05-26 | Boehringer Mannheim Gmbh | Process and device for glucose determination in a biological matrix |
US5551422A (en) | 1992-11-09 | 1996-09-03 | Boehringer Mannheim Gmbh | Method and apparatus for analytical determination of glucose in a biological matrix |
US5553616A (en) | 1993-11-30 | 1996-09-10 | Florida Institute Of Technology | Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discriminator |
US5615673A (en) | 1995-03-27 | 1997-04-01 | Massachusetts Institute Of Technology | Apparatus and methods of raman spectroscopy for analysis of blood gases and analytes |
Non-Patent Citations (3)
Title |
---|
A.J. BERGER ET AL.: "Rapid, noninvasive concentration measurements of aqueous biological analytes by near infrared Raman spectroscopy.", APPLIED OPTICS, vol. 35, no. 1, 1996, pages 209 - 212 |
R.R. ANDERSON AND J. PARRISH: "The optics of Human Skin.", J. INVESTIGATIVE DERMATOLOGY, vol. 77, no. 1, 1981, pages 13 - 19 |
S.Y. WANG ET AL.: "Analysis of metabolites in aqueous solution by using laser Raman spectroscopy.", APPLIED OPTICS, vol. 32, no. 6, 1993, pages 925 - 929 |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002003857A2 (en) * | 2000-07-11 | 2002-01-17 | Lightouch Medical, Inc. | Method of tissue modulation for noninvasive measurement of an analyte |
WO2002003857A3 (en) * | 2000-07-11 | 2002-05-23 | Lightouch Medical Inc | Method of tissue modulation for noninvasive measurement of an analyte |
US7050842B2 (en) | 2000-07-11 | 2006-05-23 | Lightouch Medical, Inc. | Method of tissue modulation for noninvasive measurement of an analyte |
JP2004504905A (en) * | 2000-08-02 | 2004-02-19 | センシス メディカル インク | Apparatus and method for reproducibly correcting local absorption and scattering coefficients at a tissue measurement site during optical sampling |
Also Published As
Publication number | Publication date |
---|---|
CA2315192A1 (en) | 1999-07-29 |
WO1999037205A8 (en) | 1999-09-02 |
JP2002500908A (en) | 2002-01-15 |
CA2315192C (en) | 2008-04-29 |
US6223063B1 (en) | 2001-04-24 |
DE69920170D1 (en) | 2004-10-21 |
ATE275867T1 (en) | 2004-10-15 |
EP1051106A1 (en) | 2000-11-15 |
EP1051106B1 (en) | 2004-09-15 |
AU2473699A (en) | 1999-08-09 |
ES2224602T3 (en) | 2005-03-01 |
DE69920170T2 (en) | 2005-09-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6223063B1 (en) | Method and device for tissue modulation | |
US6571117B1 (en) | Capillary sweet spot imaging for improving the tracking accuracy and SNR of noninvasive blood analysis methods | |
US7809418B2 (en) | Optical device components | |
US5372135A (en) | Blood constituent determination based on differential spectral analysis | |
US6377828B1 (en) | Method for non-invasive measurement of an analyte | |
AU2010232841B2 (en) | Optical spectroscopy device for non-invasive blood glucose detection and associated method of use | |
US7613487B2 (en) | Instrument for noninvasively measuring blood sugar level | |
US7961305B2 (en) | Optical device components | |
US7050842B2 (en) | Method of tissue modulation for noninvasive measurement of an analyte | |
AU749033B2 (en) | Apparatus and method for noninvasive glucose measurement | |
EP0828533B1 (en) | Method and apparatus for rapid non-invasive determination of blood composition parameters | |
CA2699626C (en) | Optical device components | |
US20050043597A1 (en) | Optical vivo probe of analyte concentration within the sterile matrix under the human nail | |
AU3968499A (en) | Non-invasive measurement of analyte in the tympanic membrane | |
JP4483052B2 (en) | Noninvasive blood glucose meter | |
JPH03173535A (en) | Glucose non-invasive measuring method |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
AK | Designated states |
Kind code of ref document: C1 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG UZ VN YU ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: C1 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
CFP | Corrected version of a pamphlet front page |
Free format text: REVISED ABSTRACT RECEIVED BY THE INTERNATIONAL BUREAU AFTER COMPLETION OF THE TECHNICAL PREPARATIONS FOR INTERNATIONAL PUBLICATION |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
ENP | Entry into the national phase |
Ref document number: 2315192 Country of ref document: CA Ref country code: CA Ref document number: 2315192 Kind code of ref document: A Format of ref document f/p: F |
|
ENP | Entry into the national phase |
Ref country code: JP Ref document number: 2000 528203 Kind code of ref document: A Format of ref document f/p: F |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1999904315 Country of ref document: EP |
|
NENP | Non-entry into the national phase |
Ref country code: KR |
|
WWP | Wipo information: published in national office |
Ref document number: 1999904315 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWG | Wipo information: grant in national office |
Ref document number: 1999904315 Country of ref document: EP |