WO1999037205A8 - Method and device for tissue modulation - Google Patents

Method and device for tissue modulation

Info

Publication number
WO1999037205A8
WO1999037205A8 PCT/US1999/001704 US9901704W WO9937205A8 WO 1999037205 A8 WO1999037205 A8 WO 1999037205A8 US 9901704 W US9901704 W US 9901704W WO 9937205 A8 WO9937205 A8 WO 9937205A8
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
region
blood
replete
apposition
Prior art date
Application number
PCT/US1999/001704
Other languages
French (fr)
Other versions
WO1999037205A1 (en
Inventor
Joseph Chaiken
Charles M Peterson
Original Assignee
Lightouch Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lightouch Medical Inc filed Critical Lightouch Medical Inc
Priority to DE69920170T priority Critical patent/DE69920170T2/en
Priority to AT99904315T priority patent/ATE275867T1/en
Priority to JP2000528203A priority patent/JP2002500908A/en
Priority to AU24736/99A priority patent/AU2473699A/en
Priority to CA002315192A priority patent/CA2315192C/en
Priority to EP99904315A priority patent/EP1051106B1/en
Publication of WO1999037205A1 publication Critical patent/WO1999037205A1/en
Publication of WO1999037205A8 publication Critical patent/WO1999037205A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552—Details of sensors specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
    • A61B5/0053—Detecting, measuring or recording by applying mechanical forces or stimuli by applying pressure, e.g. compression, indentation, palpation, grasping, gauging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • A61B5/02427—Details of sensor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Abstract

A tissue modulation device comprises an upper surface and a lower surface, the upper surface comprises a recessed region (920) adjacent to a raised region (910), wherein application of a first portion of a tissue to the raised region depresses the first portion of the tissue relative to a second portion of the tissue that is in apposition to the recessed region (920). An optically transparent region of the device is curved at the lower surface to substantially reduce backscattered light in a light path traveling through the optically transparent region to a light collection system. A method of noninvasive spectroscopic measurement of an analyte in a subject comprises applying tissue of the subject to the tissue modulation device so that the raised region depresses a first portion of tissue relative to a second portion of tissue in apposition to the recessed region; irradiating the tissue in a blood-replete and a blood-depleted state with electromagnetic radiation; and analyzing the collected spectra to determine a concentration of analyte present in the tissue, by determining the difference between the spectra of the blood-replete and blood-depleted states.
PCT/US1999/001704 1998-01-27 1999-01-27 Method and device for tissue modulation WO1999037205A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE69920170T DE69920170T2 (en) 1998-01-27 1999-01-27 DEVICE AND METHOD FOR MODULATING TISSUE
AT99904315T ATE275867T1 (en) 1998-01-27 1999-01-27 DEVICE AND METHOD FOR MODULATING TISSUE
JP2000528203A JP2002500908A (en) 1998-01-27 1999-01-27 Tissue modulation apparatus and method
AU24736/99A AU2473699A (en) 1998-01-27 1999-01-27 Method and device for tissue modulation
CA002315192A CA2315192C (en) 1998-01-27 1999-01-27 Method and device for tissue modulation
EP99904315A EP1051106B1 (en) 1998-01-27 1999-01-27 Method and device for tissue modulation

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7271098P 1998-01-27 1998-01-27
US7265898P 1998-01-27 1998-01-27
US60/072,658 1998-01-27
US60/072,710 1998-01-27

Publications (2)

Publication Number Publication Date
WO1999037205A1 WO1999037205A1 (en) 1999-07-29
WO1999037205A8 true WO1999037205A8 (en) 1999-09-02

Family

ID=26753603

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/001704 WO1999037205A1 (en) 1998-01-27 1999-01-27 Method and device for tissue modulation

Country Status (9)

Country Link
US (1) US6223063B1 (en)
EP (1) EP1051106B1 (en)
JP (1) JP2002500908A (en)
AT (1) ATE275867T1 (en)
AU (1) AU2473699A (en)
CA (1) CA2315192C (en)
DE (1) DE69920170T2 (en)
ES (1) ES2224602T3 (en)
WO (1) WO1999037205A1 (en)

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US20060063992A1 (en) * 2004-08-09 2006-03-23 Dejin Yu Method and apparatus for non-invasive measurement of blood analytes
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US8452365B2 (en) * 2005-05-25 2013-05-28 Bayer Healthcare Llc Methods of using Raman spectral information in determining analyte concentrations
WO2008024276A2 (en) * 2006-08-22 2008-02-28 Bayer Healthcare Llc A method for correcting a spectral image for optical aberrations using software
US7603151B2 (en) * 2006-08-22 2009-10-13 Bayer Healthcare Llc Non-invasive methods of using spectral information in determining analyte concentrations
CN102015020A (en) * 2008-05-09 2011-04-13 休·贝克曼 Medical device for diagnosing and treating anomalous tissue and method for doing the same
US8260402B2 (en) * 2008-06-06 2012-09-04 Longevity Link, Inc. Noninvasive measurement of carotenoids in biological tissue
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Also Published As

Publication number Publication date
CA2315192A1 (en) 1999-07-29
JP2002500908A (en) 2002-01-15
CA2315192C (en) 2008-04-29
US6223063B1 (en) 2001-04-24
DE69920170D1 (en) 2004-10-21
ATE275867T1 (en) 2004-10-15
WO1999037205A1 (en) 1999-07-29
EP1051106A1 (en) 2000-11-15
EP1051106B1 (en) 2004-09-15
AU2473699A (en) 1999-08-09
ES2224602T3 (en) 2005-03-01
DE69920170T2 (en) 2005-09-22

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