WO1999040771A3 - Concurrent flow mixing for preparing compositions comprising gene therapy vectors - Google Patents
Concurrent flow mixing for preparing compositions comprising gene therapy vectors Download PDFInfo
- Publication number
- WO1999040771A3 WO1999040771A3 PCT/US1999/003226 US9903226W WO9940771A3 WO 1999040771 A3 WO1999040771 A3 WO 1999040771A3 US 9903226 W US9903226 W US 9903226W WO 9940771 A3 WO9940771 A3 WO 9940771A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- gene therapy
- compositions
- therapy vectors
- flow mixing
- preparing compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99909489A EP1054694A2 (en) | 1998-02-13 | 1999-02-16 | Concurrent flow mixing methods and apparatuses for the preparation of gene therapy vectors and compositions prepared thereby |
AU28680/99A AU2868099A (en) | 1998-02-13 | 1999-02-16 | Concurrent flow mixing methods and apparatuses for the preparation of gene therapy vectors and compositions prepared thereby |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2335498A | 1998-02-13 | 1998-02-13 | |
US09/023,354 | 1998-02-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999040771A2 WO1999040771A2 (en) | 1999-08-19 |
WO1999040771A3 true WO1999040771A3 (en) | 1999-11-25 |
Family
ID=21814604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/003226 WO1999040771A2 (en) | 1998-02-13 | 1999-02-16 | Concurrent flow mixing for preparing compositions comprising gene therapy vectors |
Country Status (4)
Country | Link |
---|---|
US (1) | US6537813B1 (en) |
EP (1) | EP1054694A2 (en) |
AU (1) | AU2868099A (en) |
WO (1) | WO1999040771A2 (en) |
Families Citing this family (23)
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JP2001520889A (en) | 1997-10-24 | 2001-11-06 | バレンティス,インコーポレイティド | Methods for preparing polynucleotide transfection complexes |
ATE324913T1 (en) | 1998-08-14 | 2006-06-15 | Valentis Inc | CO-LYOPHILIZED COMPLEX COMPRISING A NUCLEIC ACID VECTOR AND A FORMULATION AGENT |
US20040059416A1 (en) * | 1999-06-22 | 2004-03-25 | Murray Martha M. | Biologic replacement for fibrin clot |
US6964685B2 (en) | 1999-06-22 | 2005-11-15 | The Brigham And Women's Hospital, Inc. | Biologic replacement for fibrin clot |
US20050037086A1 (en) * | 1999-11-19 | 2005-02-17 | Zycos Inc., A Delaware Corporation | Continuous-flow method for preparing microparticles |
PT1295611E (en) * | 2000-06-20 | 2010-09-14 | Dainippon Sumitomo Pharma Co | Oligonucleotide-transferring preparations |
KR100888566B1 (en) * | 2001-06-20 | 2009-03-12 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | Method of promoting nucleic acid transfer |
KR20040104579A (en) * | 2002-04-24 | 2004-12-10 | 가부시키가이샤 바이오 메디아 | Method of measuring formaldehyde concentration of gas and measuring instrument |
EP1581201A4 (en) * | 2002-12-23 | 2011-03-30 | Vical Inc | Method for producing sterile polynucleotide based medicaments |
JP4954550B2 (en) * | 2003-12-19 | 2012-06-20 | 大日本住友製薬株式会社 | Novel nucleic acid introduction method |
WO2005089926A1 (en) * | 2004-03-23 | 2005-09-29 | Kyowa Hakko Kogyo Co., Ltd. | Method for producing coated fine particles |
US7638477B2 (en) * | 2005-03-09 | 2009-12-29 | Alberto-Culver Company | Sustained-release fragrance delivery system |
US20090062184A1 (en) * | 2005-03-24 | 2009-03-05 | Dainippon Sumitomo Pharma Co., Ltd. | Fine particulate preparation comprising complex of nucleic acid molecule and collagen |
US20090306776A1 (en) | 2006-01-25 | 2009-12-10 | Children's Medical Center Corporation | Methods and procedures for ligament repair |
NZ571965A (en) * | 2006-03-30 | 2012-02-24 | Engene Inc | Chitosan-based nanoparticles and methods for transfecting gut cells in vivo |
JP2010509943A (en) | 2006-09-28 | 2010-04-02 | チルドレンズ メディカル センター コーポレーション | Method of repairing tissue and collagen product therefor |
DE102007015136A1 (en) * | 2007-03-29 | 2008-10-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Shear stress application |
WO2009039657A1 (en) * | 2007-09-28 | 2009-04-02 | Engene, Inc. | High concentration chitosan-nucleic acid polyplex compositions |
RU2013145080A (en) | 2011-03-09 | 2015-04-20 | Пикселл Медикал Текнолоджиз Лтд. | DISPOSABLE CARTRIDGE FOR PREPARING A Sample OF A FLUID CONTAINING A CELL FOR ANALYSIS |
WO2013116744A1 (en) | 2012-02-01 | 2013-08-08 | Children's Medical Center Corporation | Biomaterial for articular cartilage maintenance and treatment of arthritis |
EP3798226A1 (en) | 2013-02-01 | 2021-03-31 | Children's Medical Center Corporation | Collagen scaffolds |
WO2018041921A1 (en) | 2016-08-31 | 2018-03-08 | Curevac Ag | Mixing device for the production of a liquid nucleic acid composition |
AU2021404929A1 (en) * | 2020-12-21 | 2023-07-06 | Pfizer Inc. | Methods and systems for improved cell transfection |
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US5116315A (en) * | 1989-10-03 | 1992-05-26 | Hemaedics, Inc. | Biological syringe system |
US5354844A (en) * | 1989-03-16 | 1994-10-11 | Boehringer Ingelheim International Gmbh | Protein-polycation conjugates |
US5505704A (en) * | 1993-04-02 | 1996-04-09 | Eli Lilly And Company | Manifold medication injection apparatus and method |
WO1996012006A2 (en) * | 1994-10-12 | 1996-04-25 | Genetronics, Inc. | Flow through electroporation apparatus and method |
US5595897A (en) * | 1994-04-28 | 1997-01-21 | I.D.M. Immuno-Designed Molecules | Polylysine conjugates |
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-
1999
- 1999-02-16 EP EP99909489A patent/EP1054694A2/en not_active Withdrawn
- 1999-02-16 AU AU28680/99A patent/AU2868099A/en not_active Abandoned
- 1999-02-16 WO PCT/US1999/003226 patent/WO1999040771A2/en not_active Application Discontinuation
- 1999-02-16 US US09/250,839 patent/US6537813B1/en not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5354844A (en) * | 1989-03-16 | 1994-10-11 | Boehringer Ingelheim International Gmbh | Protein-polycation conjugates |
US5116315A (en) * | 1989-10-03 | 1992-05-26 | Hemaedics, Inc. | Biological syringe system |
US5505704A (en) * | 1993-04-02 | 1996-04-09 | Eli Lilly And Company | Manifold medication injection apparatus and method |
US5595897A (en) * | 1994-04-28 | 1997-01-21 | I.D.M. Immuno-Designed Molecules | Polylysine conjugates |
WO1996012006A2 (en) * | 1994-10-12 | 1996-04-25 | Genetronics, Inc. | Flow through electroporation apparatus and method |
Non-Patent Citations (1)
Title |
---|
DAVIS, LAWRENCE C. ET AL: "A simple, reliable rapid-mixing apparatus for continuous-flow studies", ANAL. BIOCHEM. (1979), 97(2), 428-37, XP002114959 * |
Also Published As
Publication number | Publication date |
---|---|
AU2868099A (en) | 1999-08-30 |
EP1054694A2 (en) | 2000-11-29 |
US6537813B1 (en) | 2003-03-25 |
WO1999040771A2 (en) | 1999-08-19 |
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