WO1999045982A3 - A catheter to be inserted into a blood vessel, and a method for detection of substances - Google Patents

A catheter to be inserted into a blood vessel, and a method for detection of substances Download PDF

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Publication number
WO1999045982A3
WO1999045982A3 PCT/SE1999/000259 SE9900259W WO9945982A3 WO 1999045982 A3 WO1999045982 A3 WO 1999045982A3 SE 9900259 W SE9900259 W SE 9900259W WO 9945982 A3 WO9945982 A3 WO 9945982A3
Authority
WO
WIPO (PCT)
Prior art keywords
catheter
microdialysis
channel
blood vessel
catheter body
Prior art date
Application number
PCT/SE1999/000259
Other languages
French (fr)
Other versions
WO1999045982A2 (en
Inventor
Jan Liska
Anders Franco-Cereceda
Original Assignee
Jan Liska
Franco Cereceda Anders
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9800791A external-priority patent/SE511933C2/en
Application filed by Jan Liska, Franco Cereceda Anders filed Critical Jan Liska
Priority to AU28635/99A priority Critical patent/AU2863599A/en
Priority to EP99909435A priority patent/EP1061969A2/en
Publication of WO1999045982A2 publication Critical patent/WO1999045982A2/en
Publication of WO1999045982A3 publication Critical patent/WO1999045982A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14525—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using microdialysis
    • A61B5/14528—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using microdialysis invasively
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/28—Apparatus therefor

Abstract

A catheter (1) to be inserted into and guided by a blood vessel, and a method for detecting substances in the coronary sinus. The catheter (1) comprises an elongate catheter body (2), having a distal end and a proximal end, and includes at least two channels (23, 24). A first and second channel (23, 24) for microdialysis solution are connected with each other so that microdialysis solution can flow from one channel to the other. An opening (25), in connection with which a microdialysis membrane (30) is arranged, is provided in the catheter body (2). A space (26) in the catheter body is formed by a part of the first channel in connection with said opening and forms a microdialysis chamber (26). The catheter is connectable to external means (10) for circulating and monitoring/analyzing the dialysis solution. In the method the concentration of at least one substance in a group, in a sample of a dialysis solution obtained by microdialysis of blood in the vascular system, e.g. in the coronary sinus, is measured and possibly compared with a reference concentration for the respective substance measured.
PCT/SE1999/000259 1998-03-11 1999-02-24 A catheter to be inserted into a blood vessel, and a method for detection of substances WO1999045982A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU28635/99A AU2863599A (en) 1998-03-11 1999-02-24 A catheter to be inserted into a blood vessel, and a method for detection of substances
EP99909435A EP1061969A2 (en) 1998-03-11 1999-02-24 A catheter to be inserted into a blood vessel, and a method for detection of substances

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9800791-7 1998-03-11
SE9800791A SE511933C2 (en) 1998-03-11 1998-03-11 Catheter designed to be inserted into a blood vessel
SE9804081A SE511932C2 (en) 1998-03-11 1998-11-26 A method and catheter for detecting substances
SE9804081-9 1998-11-26

Publications (2)

Publication Number Publication Date
WO1999045982A2 WO1999045982A2 (en) 1999-09-16
WO1999045982A3 true WO1999045982A3 (en) 1999-11-25

Family

ID=26663231

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SE1999/000259 WO1999045982A2 (en) 1998-03-11 1999-02-24 A catheter to be inserted into a blood vessel, and a method for detection of substances

Country Status (4)

Country Link
EP (1) EP1061969A2 (en)
AU (1) AU2863599A (en)
SE (1) SE511932C2 (en)
WO (1) WO1999045982A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE20021360U1 (en) * 2000-12-18 2001-03-22 Mueller Geraetebau Gmbh Dr Blood analysis device for determining blood constituents
AT412060B (en) * 2001-07-06 2004-09-27 Schaupp Lukas Dipl Ing Dr Tech METHOD FOR MEASURING CONCENTRATIONS IN LIVING ORGANISMS BY MEANS OF MICRODIALYSIS AND AND DEVICE FOR IMPLEMENTING THIS METHOD
DE10247023B4 (en) * 2002-10-09 2006-07-20 Disetronic Licensing Ag Microdialysis probe and method for its production
US8741555B2 (en) * 2004-05-14 2014-06-03 Organ Recovery Systems, Inc. Apparatus and method for perfusion and determining the viability of an organ
EP1940297A1 (en) * 2005-10-27 2008-07-09 Cma/Microdialysis Ab Microdialysis probe
US10176887B1 (en) 2005-11-14 2019-01-08 Organ Recovery Systems, Inc. Ex vivo methods for drug discovery, development and testing
DE602007011563D1 (en) 2006-10-19 2011-02-10 Joanneum Res Forschungsges M B H DEVICE FOR ANALYZING A FLUID SAMPLE THROUGH MICRODIALYSIS AND METHOD FOR MONITORING A PARAMETER OF A FLUID SAMPLE
EP1922987A1 (en) 2006-11-17 2008-05-21 Trace Analytics GmbH Sampling device and sampling method
US8771930B2 (en) 2007-05-18 2014-07-08 Lifeline Scientific, Inc. Ex vivo methods for testing toxicity of substances using donated human organs or tissues
US8765364B2 (en) 2007-05-18 2014-07-01 Lifeline Scientific, Inc. Ex vivo methods for validating substance testing with human organs and/or tissues
WO2009095020A1 (en) * 2008-01-30 2009-08-06 Diramo A/S A micro-dialysis probe and a method of making the probe
EP2391275B1 (en) 2008-12-09 2018-04-25 MD Biomedical AB Device for microdialysis sampling
DE102009001455B4 (en) 2009-03-10 2021-10-14 Trace Analytics Gmbh Sampling device and method
WO2010103051A1 (en) 2009-03-10 2010-09-16 Trace Analytics Gmbh Sampling device and sampling method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340615A (en) * 1979-06-07 1982-07-20 The Medishield Corporation Limited Apparatus for analysis of absorbed gases
JPS61206459A (en) * 1985-03-11 1986-09-12 株式会社日立製作所 Catheter
US4694832A (en) * 1982-12-01 1987-09-22 Ungerstedt Carl U Dialysis probe
US5097834A (en) * 1987-02-02 1992-03-24 Avl Ag Process for determining parameters of interest in living organisms
US5690103A (en) * 1996-06-20 1997-11-25 Groth; Torgny Lars Detection/exclusion of acute myocardial infarction using neural network analysis of measurements of biochemical markers

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340615A (en) * 1979-06-07 1982-07-20 The Medishield Corporation Limited Apparatus for analysis of absorbed gases
US4694832A (en) * 1982-12-01 1987-09-22 Ungerstedt Carl U Dialysis probe
JPS61206459A (en) * 1985-03-11 1986-09-12 株式会社日立製作所 Catheter
US5097834A (en) * 1987-02-02 1992-03-24 Avl Ag Process for determining parameters of interest in living organisms
US5690103A (en) * 1996-06-20 1997-11-25 Groth; Torgny Lars Detection/exclusion of acute myocardial infarction using neural network analysis of measurements of biochemical markers

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 8643, Derwent World Patents Index; AN 86-282132, XP002921010 *
PATENT ABSTRACTS OF JAPAN *
XP002919909 *

Also Published As

Publication number Publication date
WO1999045982A2 (en) 1999-09-16
EP1061969A2 (en) 2000-12-27
SE9804081D0 (en) 1998-11-26
SE511932C2 (en) 1999-12-20
AU2863599A (en) 1999-09-27
SE9804081L (en) 1999-09-12

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