WO1999047552A3 - Genes encoding mlo proteins and conferring fungal resistance upon plants - Google Patents

Genes encoding mlo proteins and conferring fungal resistance upon plants Download PDF

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Publication number
WO1999047552A3
WO1999047552A3 PCT/EP1999/001779 EP9901779W WO9947552A3 WO 1999047552 A3 WO1999047552 A3 WO 1999047552A3 EP 9901779 W EP9901779 W EP 9901779W WO 9947552 A3 WO9947552 A3 WO 9947552A3
Authority
WO
WIPO (PCT)
Prior art keywords
plants
genes encoding
fungal pathogens
fungal resistance
mlo proteins
Prior art date
Application number
PCT/EP1999/001779
Other languages
French (fr)
Other versions
WO1999047552A2 (en
Inventor
John Manuel Salmeron
Laura Jean Weislo
Leslie Jean Strawn
Catherine Mae Kramer
Original Assignee
Novartis Ag
Novartis Erfind Verwalt Gmbh
John Manuel Salmeron
Laura Jean Weislo
Leslie Jean Strawn
Catherine Mae Kramer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Novartis Erfind Verwalt Gmbh, John Manuel Salmeron, Laura Jean Weislo, Leslie Jean Strawn, Catherine Mae Kramer filed Critical Novartis Ag
Priority to JP2000536743A priority Critical patent/JP2002512775A/en
Priority to CA002322016A priority patent/CA2322016A1/en
Priority to BR9908851-7A priority patent/BR9908851A/en
Priority to EP99914522A priority patent/EP1064304A2/en
Priority to PL99343599A priority patent/PL343599A1/en
Priority to KR1020007010255A priority patent/KR20010041943A/en
Priority to AU33311/99A priority patent/AU3331199A/en
Priority to EA200000952A priority patent/EA200000952A1/en
Priority to IL13834199A priority patent/IL138341A0/en
Priority to HU0102051A priority patent/HUP0102051A2/en
Publication of WO1999047552A2 publication Critical patent/WO1999047552A2/en
Publication of WO1999047552A3 publication Critical patent/WO1999047552A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

This invention describes genes encoding proteins which control resistance of plants to fungal pathogens. The invention also describes transgenic plants resistant to fungal pathogens and methods for making plants resistant to fungal pathogens. The invention further discloses a method to isolate additional genes coding for additional proteins controlling the resistance of plants to fungal pathogens.
PCT/EP1999/001779 1998-03-17 1999-03-17 Genes encoding mlo proteins and conferring fungal resistance upon plants WO1999047552A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP2000536743A JP2002512775A (en) 1998-03-17 1999-03-17 Gene that encodes MLO protein and confers fungal resistance to plants
CA002322016A CA2322016A1 (en) 1998-03-17 1999-03-17 Genes encoding mlo proteins and conferring fungal resistance upon plants
BR9908851-7A BR9908851A (en) 1998-03-17 1999-03-17 Genes encoding mlo proteins and providing fungal resistance to plants
EP99914522A EP1064304A2 (en) 1998-03-17 1999-03-17 Genes encoding mlo proteins and conferring fungal resistance upon plants
PL99343599A PL343599A1 (en) 1998-03-17 1999-03-17 Genes controlling diseases
KR1020007010255A KR20010041943A (en) 1998-03-17 1999-03-17 Genes encoding MLO proteins and conferring fungal resistance upon plants
AU33311/99A AU3331199A (en) 1998-03-17 1999-03-17 Genes controlling diseases
EA200000952A EA200000952A1 (en) 1998-03-17 1999-03-17 GENES CODING MLO PROTEINS AND CAUSING PLANT RESISTANCE TO MUSHROOMS
IL13834199A IL138341A0 (en) 1998-03-17 1999-03-17 Genes encoding mlo proteins and conferring fungal resistance upon plants
HU0102051A HUP0102051A2 (en) 1998-03-17 1999-03-17 Genes controlling diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4276398A 1998-03-17 1998-03-17
US09/042,763 1998-03-17

Publications (2)

Publication Number Publication Date
WO1999047552A2 WO1999047552A2 (en) 1999-09-23
WO1999047552A3 true WO1999047552A3 (en) 1999-11-18

Family

ID=21923620

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/001779 WO1999047552A2 (en) 1998-03-17 1999-03-17 Genes encoding mlo proteins and conferring fungal resistance upon plants

Country Status (14)

Country Link
EP (1) EP1064304A2 (en)
JP (1) JP2002512775A (en)
KR (1) KR20010041943A (en)
CN (1) CN1293711A (en)
AU (1) AU3331199A (en)
BR (1) BR9908851A (en)
CA (1) CA2322016A1 (en)
EA (1) EA200000952A1 (en)
HU (1) HUP0102051A2 (en)
ID (1) ID25781A (en)
IL (1) IL138341A0 (en)
PL (1) PL343599A1 (en)
TR (1) TR200002537T2 (en)
WO (1) WO1999047552A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5815500A (en) * 1999-06-18 2001-01-09 Novartis Ag Genes controlling diseases
US6864404B1 (en) * 1999-10-15 2005-03-08 Carnegie Institution Of Washington Engineering disease resistance with pectate lyase-like genes
GB0015122D0 (en) * 2000-06-20 2000-08-09 Plant Bioscience Ltd Plant resistance gene
EP1925672A1 (en) 2001-06-22 2008-05-28 Syngeta Participations AG Abiotic stress responsive polynucleotides and polypeptides
US7456335B2 (en) 2001-09-03 2008-11-25 Basf Plant Science Gmbh Nucleic acid sequences and their use in methods for achieving pathogen resistance in plants
US7572950B2 (en) 2002-07-04 2009-08-11 Sungene Gmbh & Co. Kgaa Methods for obtaining pathogen resistance in plants
DE10233327A1 (en) 2002-07-22 2004-02-05 Basf Ag Process for achieving pathogen resistance in plants
US20070169227A1 (en) 2003-12-16 2007-07-19 Pioneer Hi-Bred International Inc. Dominant Gene Suppression Transgenes and Methods of Using Same
PL2141239T3 (en) 2003-12-16 2014-02-28 Pioneer Hi Bred Int Dominant gene suppression transgenes and methods of using same
EP1948806A2 (en) 2005-11-08 2008-07-30 BASF Plant Science GmbH Use of armadillo repeat (arm1) polynucleotides for obtaining pathogen resistance in plants
CA2632872A1 (en) 2006-01-12 2007-07-19 Basf Plant Science Gmbh Use of stomatin (stm1) polynucleotides for achieving a pathogen resistance in plants
EP2059600B1 (en) 2006-08-30 2014-04-02 BASF Plant Science GmbH Method for increasing resistance to pathogens in transgenic plants
WO2008043826A1 (en) 2006-10-12 2008-04-17 Basf Plant Science Gmbh Method for increasing pathogen resistance in transgenic plants
EP2081954B1 (en) 2006-10-24 2012-06-13 BASF Plant Science GmbH Methods for increasing the resistance of plants to fungi
WO2008087141A2 (en) 2007-01-15 2008-07-24 Basf Plant Science Gmbh Use of subtilisin (rnr9) polynucleotides for achieving a pathogen resistance in plants
TR201819455T4 (en) * 2011-03-01 2019-01-21 Enza Zaden Beheer Bv Providing Melon Powdery Resistance
CN104561031A (en) * 2013-10-28 2015-04-29 常熟市董浜镇里睦蔬菜专业合作社 Quick identification of MLO powdery mildew resistant gene for citrus
CN104593379A (en) * 2013-10-30 2015-05-06 江苏省常熟现代农业产业园区发展有限公司 Rapid identification of powdery mildew resistant gene of Chinese cabbage by using comparative genomics
EP3097194A4 (en) 2014-01-21 2017-08-23 Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences Modified plants
CN108291235B (en) * 2015-10-07 2021-11-30 埃德蒙马赫基金会 Resistance conferring genes for byssus simplex capsula albuginea in apples
CN115942867A (en) * 2019-02-23 2023-04-07 优良种子有限责任公司 Powdery mildew resistant cannabis plant
CN111826454B (en) * 2019-04-23 2022-08-02 江苏省农业科学院 Molecular marker VrMLO _ Indel2 for identifying powdery mildew resistance phenotype of mung beans as well as primer and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4009990A1 (en) * 1990-03-28 1991-10-02 Btc Biotech Int Phytosanitary agent for prevention and treatment of plant diseases - contains natural carboxylic acids and/or aminoacid(s), purine(s) and/or pyrimidine(s) and vitamin(s)
WO1995022625A1 (en) * 1994-02-17 1995-08-24 Affymax Technologies N.V. Dna mutagenesis by random fragmentation and reassembly
WO1997037024A2 (en) * 1996-03-29 1997-10-09 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
WO1998004586A2 (en) * 1996-07-29 1998-02-05 Plant Bioscience Limited Polynucleotide and its use for modulating a defence response in plants
WO1999023235A1 (en) * 1997-11-05 1999-05-14 E.I. Du Pont De Nemours And Company CORN cDNA ENCODING SOUTHERN LEAF BLIGHT RESISTANCE PROTEIN

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4009990A1 (en) * 1990-03-28 1991-10-02 Btc Biotech Int Phytosanitary agent for prevention and treatment of plant diseases - contains natural carboxylic acids and/or aminoacid(s), purine(s) and/or pyrimidine(s) and vitamin(s)
WO1995022625A1 (en) * 1994-02-17 1995-08-24 Affymax Technologies N.V. Dna mutagenesis by random fragmentation and reassembly
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
WO1997037024A2 (en) * 1996-03-29 1997-10-09 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
WO1998004586A2 (en) * 1996-07-29 1998-02-05 Plant Bioscience Limited Polynucleotide and its use for modulating a defence response in plants
WO1999023235A1 (en) * 1997-11-05 1999-05-14 E.I. Du Pont De Nemours And Company CORN cDNA ENCODING SOUTHERN LEAF BLIGHT RESISTANCE PROTEIN

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BUESCHGES R ET AL: "THE BARLEY MLO GENE: A NOVEL CONTROL ELEMENT OF PLANT PATHOGEN RESISTANCE", CELL, vol. 88, no. 5, 7 March 1997 (1997-03-07), pages 695 - 705, XP002035301 *

Also Published As

Publication number Publication date
ID25781A (en) 2000-11-02
CN1293711A (en) 2001-05-02
TR200002537T2 (en) 2000-11-21
JP2002512775A (en) 2002-05-08
CA2322016A1 (en) 1999-09-23
HUP0102051A2 (en) 2001-10-28
BR9908851A (en) 2000-12-12
PL343599A1 (en) 2001-08-27
AU3331199A (en) 1999-10-11
KR20010041943A (en) 2001-05-25
EP1064304A2 (en) 2001-01-03
IL138341A0 (en) 2001-10-31
EA200000952A1 (en) 2001-06-25
WO1999047552A2 (en) 1999-09-23

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