WO1999062495A3 - Dry powder dispersing apparatus and methods for their use - Google Patents

Dry powder dispersing apparatus and methods for their use Download PDF

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Publication number
WO1999062495A3
WO1999062495A3 PCT/US1999/011180 US9911180W WO9962495A3 WO 1999062495 A3 WO1999062495 A3 WO 1999062495A3 US 9911180 W US9911180 W US 9911180W WO 9962495 A3 WO9962495 A3 WO 9962495A3
Authority
WO
WIPO (PCT)
Prior art keywords
receptacle
interlock
methods
cylinder
carriage assembly
Prior art date
Application number
PCT/US1999/011180
Other languages
French (fr)
Other versions
WO1999062495A2 (en
Inventor
John D Burr
Adrian E Smith
Randy K Hall
Herm Snyder
Carlos Schuler
George S Axford
Charles Ray
Original Assignee
Inhale Therapeutic Syst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to APAP/P/2000/001997A priority Critical patent/AP1443A/en
Priority to EEP200000721A priority patent/EE04706B1/en
Priority to AU40905/99A priority patent/AU775629B2/en
Priority to SI9930925T priority patent/SI1082155T1/en
Priority to JP2000551751A priority patent/JP4044734B2/en
Priority to EA200100007A priority patent/EA002869B1/en
Priority to DE69933210T priority patent/DE69933210T2/en
Priority to CA002332853A priority patent/CA2332853C/en
Priority to EP99924396A priority patent/EP1082155B1/en
Priority to UA2001010117A priority patent/UA68382C2/en
Priority to PL345179A priority patent/PL196080B1/en
Priority to DK99924396T priority patent/DK1082155T3/en
Priority to IL13979199A priority patent/IL139791A/en
Priority to SK1816-2000A priority patent/SK285882B6/en
Application filed by Inhale Therapeutic Syst filed Critical Inhale Therapeutic Syst
Priority to NZ508536A priority patent/NZ508536A/en
Priority to BR9910931-0A priority patent/BR9910931A/en
Priority to HU0103610A priority patent/HUP0103610A3/en
Publication of WO1999062495A2 publication Critical patent/WO1999062495A2/en
Publication of WO1999062495A3 publication Critical patent/WO1999062495A3/en
Priority to IS5734A priority patent/IS5734A/en
Priority to NO20006167A priority patent/NO20006167L/en
Priority to HR20010008A priority patent/HRP20010008A2/en
Priority to HK01102074A priority patent/HK1031696A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • A61M15/0036Piercing means hollow piercing means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • A61M2205/071General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073Syringe, piston type

Abstract

The invention provides various apparatus and methods for aerosolizing a powdered medicament. In one exemplary embodiment, an apparatus includes a pressurization cylinder, and a piston which is slidable within the cylinder to pressurize a gas. A handle is coupled to the piston and is movable between an extended position and a home position to pressurize the gas. An aerosolizing mechanism is included and is configured to aerosolize a powdered medicament that is held within a receptacle with pressurized gas from the cylinder. A carriage assembly is included to receive the receptacle and to couple the receptacle to the aerosolizing mechanism. A first and a second interlock are operably engageable with the carriage assembly to prevent coupling of the receptacle with the aerosolization mechanism. The first interlock is released to allow movement of the carriage upon movement of the handle to the extended position. The second interlock remains engaged if the receptacle is only partially inserted into the carriage assembly.
PCT/US1999/011180 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use WO1999062495A2 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
BR9910931-0A BR9910931A (en) 1998-06-04 1999-05-19 Apparatus, process, system and device for aerolizing a sprayed medicine, and process for administering a sprayed medicine to a patient
AU40905/99A AU775629B2 (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use
SI9930925T SI1082155T1 (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use
JP2000551751A JP4044734B2 (en) 1998-06-04 1999-05-19 Device for aerosolizing powdered drugs
EA200100007A EA002869B1 (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use
DE69933210T DE69933210T2 (en) 1998-06-04 1999-05-19 Dispensers for dry powder and their application method
CA002332853A CA2332853C (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use
EP99924396A EP1082155B1 (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use
UA2001010117A UA68382C2 (en) 1998-06-04 1999-05-19 Apparatus for aerosolizing powdered medicament (variants) method and system for aerosolizing powdered medicament, method for delivery of aerosolized medicament (variants)
PL345179A PL196080B1 (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use
DK99924396T DK1082155T3 (en) 1998-06-04 1999-05-19 Dispersion dispensers for dry powder and methods for using them
APAP/P/2000/001997A AP1443A (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use.
SK1816-2000A SK285882B6 (en) 1998-06-04 1999-05-19 Apparatus for aerosolizing a powdered medicament and method of using thereof
IL13979199A IL139791A (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use
NZ508536A NZ508536A (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use
EEP200000721A EE04706B1 (en) 1998-06-04 1999-05-19 Apparatus for aerosolizing a powdered medicament and methods for using it
HU0103610A HUP0103610A3 (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use
IS5734A IS5734A (en) 1999-05-19 2000-11-24 Powder distribution device and method
NO20006167A NO20006167L (en) 1998-06-04 2000-12-04 Dry powder spreading apparatus and method for its use
HR20010008A HRP20010008A2 (en) 1998-06-04 2001-01-03 Dry powder dispersing apparatus and methods for their use
HK01102074A HK1031696A1 (en) 1998-06-04 2001-03-22 Dry powder dispersing apparatus and methods for their use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8792998P 1998-06-04 1998-06-04
US60/087,929 1998-06-04
US09/312,434 US6257233B1 (en) 1998-06-04 1999-05-14 Dry powder dispersing apparatus and methods for their use
US09/312,434 1999-05-14

Publications (2)

Publication Number Publication Date
WO1999062495A2 WO1999062495A2 (en) 1999-12-09
WO1999062495A3 true WO1999062495A3 (en) 2000-02-10

Family

ID=26777530

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/011180 WO1999062495A2 (en) 1998-06-04 1999-05-19 Dry powder dispersing apparatus and methods for their use

Country Status (41)

Country Link
US (5) US6257233B1 (en)
EP (1) EP1082155B1 (en)
JP (2) JP4044734B2 (en)
KR (1) KR100608118B1 (en)
CN (1) CN1217711C (en)
AP (1) AP1443A (en)
AR (1) AR018443A1 (en)
AT (1) ATE339232T1 (en)
AU (1) AU775629B2 (en)
BG (1) BG65349B1 (en)
BR (1) BR9910931A (en)
CA (1) CA2332853C (en)
CO (1) CO5021133A1 (en)
DE (1) DE69933210T2 (en)
DK (1) DK1082155T3 (en)
DZ (1) DZ2810A1 (en)
EA (1) EA002869B1 (en)
EE (1) EE04706B1 (en)
ES (1) ES2273490T3 (en)
HK (1) HK1031696A1 (en)
HR (1) HRP20010008A2 (en)
HU (1) HUP0103610A3 (en)
ID (1) ID29131A (en)
IL (1) IL139791A (en)
IS (1) IS5706A (en)
MA (1) MA24907A1 (en)
MY (1) MY135967A (en)
NO (1) NO20006167L (en)
NZ (1) NZ508536A (en)
OA (1) OA11692A (en)
PA (1) PA8474901A1 (en)
PE (1) PE20000626A1 (en)
PL (1) PL196080B1 (en)
PT (1) PT1082155E (en)
RS (1) RS49669B (en)
SA (1) SA99200468B1 (en)
SK (1) SK285882B6 (en)
TR (1) TR200003611T2 (en)
TW (1) TW509069U (en)
UY (1) UY25537A1 (en)
WO (1) WO1999062495A2 (en)

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DE69933210D1 (en) 2006-10-26
AP1443A (en) 2005-06-30
US20080230058A1 (en) 2008-09-25
KR100608118B1 (en) 2006-08-02
HRP20010008A2 (en) 2001-12-31
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CN1312729A (en) 2001-09-12
JP2008068114A (en) 2008-03-27
NO20006167L (en) 2001-02-05
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EP1082155B1 (en) 2006-09-13
US6257233B1 (en) 2001-07-10
WO1999062495A2 (en) 1999-12-09
US20020017297A1 (en) 2002-02-14
CA2332853C (en) 2008-03-18
JP2003527136A (en) 2003-09-16
OA11692A (en) 2005-01-12
TR200003611T2 (en) 2001-06-21
IL139791A0 (en) 2002-02-10
AU4090599A (en) 1999-12-20
SK18162000A3 (en) 2002-07-02
CA2332853A1 (en) 1999-12-09
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KR20010071400A (en) 2001-07-28
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US7422013B2 (en) 2008-09-09
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RS49669B (en) 2007-09-21
IS5706A (en) 2000-11-07
US6901929B2 (en) 2005-06-07
AP2000001997A0 (en) 2000-12-31
MA24907A1 (en) 2000-04-01

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