WO2000001350A3 - Material zur modifizierung der optischen eigenschaften unterschiedlicher zellen, gerät zum applizieren dieses materiales, diagnosegärat zum bestimmen der optischen eigenschaften von zellen, sowie gerät zum bestrahlen von zellen - Google Patents

Material zur modifizierung der optischen eigenschaften unterschiedlicher zellen, gerät zum applizieren dieses materiales, diagnosegärat zum bestimmen der optischen eigenschaften von zellen, sowie gerät zum bestrahlen von zellen Download PDF

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Publication number
WO2000001350A3
WO2000001350A3 PCT/EP1999/003778 EP9903778W WO0001350A3 WO 2000001350 A3 WO2000001350 A3 WO 2000001350A3 EP 9903778 W EP9903778 W EP 9903778W WO 0001350 A3 WO0001350 A3 WO 0001350A3
Authority
WO
WIPO (PCT)
Prior art keywords
cells
optical properties
modifying
applying
determining
Prior art date
Application number
PCT/EP1999/003778
Other languages
English (en)
French (fr)
Other versions
WO2000001350A2 (de
Inventor
Rainer Hahn
Klaus Irion
Original Assignee
Rainer Hahn
Klaus Irion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rainer Hahn, Klaus Irion filed Critical Rainer Hahn
Priority to EP99926492A priority Critical patent/EP1087793B1/de
Priority to CA002335113A priority patent/CA2335113A1/en
Priority to AU43725/99A priority patent/AU4372599A/en
Priority to DE59913128T priority patent/DE59913128D1/de
Priority to US09/720,232 priority patent/US6699040B1/en
Publication of WO2000001350A2 publication Critical patent/WO2000001350A2/de
Publication of WO2000001350A3 publication Critical patent/WO2000001350A3/de
Priority to US10/753,799 priority patent/US7163397B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0088—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for oral or dental tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0073—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form semi-solid, gel, hydrogel, ointment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/90—Compositions for taking dental impressions

Abstract

Es wird ein Modifikationsmaterial vorgeschlagen, welches eine Modifikationssubstanz enthält, welche die Fluoreszenz kranker Zellen oder von Bakterien verstärkt, indem sie die Produktion von Stoffwechselzwischenprodukten des Stoffwechsels verstärkt, die fluoreszieren. Ein Grundmaterial des Modifikationsmateriales ist verglichen mit Wasser formstabil und hält so die Modifikationssubstanz in Kontakt zu dem zu untersuchenden Gewebebereich, bis eine ausreichende Menge der Modifikationssubstanz verstoffwechselt ist.
PCT/EP1999/003778 1998-06-19 1999-06-01 Material zur modifizierung der optischen eigenschaften unterschiedlicher zellen, gerät zum applizieren dieses materiales, diagnosegärat zum bestimmen der optischen eigenschaften von zellen, sowie gerät zum bestrahlen von zellen WO2000001350A2 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP99926492A EP1087793B1 (de) 1998-06-19 1999-06-01 Material zur modifizierung der optischen eigenschaften unterschiedlicher zellen und gerät zum applizieren dieses materials
CA002335113A CA2335113A1 (en) 1998-06-19 1999-06-01 Material for modifying the optical properties of different cells, device for applying such a material, diagnostic apparatus for determining the optical properties of cells and device for irradiating cells
AU43725/99A AU4372599A (en) 1998-06-19 1999-06-01 Material for differently modifying the optical properties of different cells
DE59913128T DE59913128D1 (de) 1998-06-19 1999-06-01 Material zur modifizierung der optischen eigenschaften unterschiedlicher zellen und gerät zum applizieren dieses materials
US09/720,232 US6699040B1 (en) 1998-06-19 1999-06-11 Material for differently modifying the optical properties of different cells
US10/753,799 US7163397B2 (en) 1998-06-19 2004-01-08 Apparatus for applying material for selectively modifying the optical properties of metabolically different cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1998127417 DE19827417B4 (de) 1998-06-19 1998-06-19 Material zur unterschiedlichen Modifizierung der optischen Eigenschaften unterschiedlicher Zellen
DE19827417.3 1998-06-19

Related Child Applications (5)

Application Number Title Priority Date Filing Date
US09720232 A-371-Of-International 1999-06-01
US09/720,232 A-371-Of-International US6699040B1 (en) 1998-06-19 1999-06-11 Material for differently modifying the optical properties of different cells
US10/753,939 Division US20040248058A1 (en) 1998-06-19 2004-01-08 Material for differently modifying the optical properties of different cells
US10/753,835 Division US20040248061A1 (en) 1998-06-19 2004-01-08 Material for differently modifying the optical properties of different cells
US10/753,799 Division US7163397B2 (en) 1998-06-19 2004-01-08 Apparatus for applying material for selectively modifying the optical properties of metabolically different cells

Publications (2)

Publication Number Publication Date
WO2000001350A2 WO2000001350A2 (de) 2000-01-13
WO2000001350A3 true WO2000001350A3 (de) 2000-06-22

Family

ID=7871448

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP1999/003778 WO2000001350A2 (de) 1998-06-19 1999-06-01 Material zur modifizierung der optischen eigenschaften unterschiedlicher zellen, gerät zum applizieren dieses materiales, diagnosegärat zum bestimmen der optischen eigenschaften von zellen, sowie gerät zum bestrahlen von zellen
PCT/EP1999/004242 WO1999066831A2 (de) 1998-06-19 1999-06-18 Verwendung von 5-aminolävulinsäure oder eines derivates davon zur photodynamischen diagnose und/oder photodynamischen therapie von erkrankungen des zahnhalteapparates und der zähne

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/004242 WO1999066831A2 (de) 1998-06-19 1999-06-18 Verwendung von 5-aminolävulinsäure oder eines derivates davon zur photodynamischen diagnose und/oder photodynamischen therapie von erkrankungen des zahnhalteapparates und der zähne

Country Status (7)

Country Link
US (6) US6699040B1 (de)
EP (2) EP1087793B1 (de)
AT (1) ATE317704T1 (de)
AU (1) AU4372599A (de)
CA (1) CA2335113A1 (de)
DE (3) DE19827417B4 (de)
WO (2) WO2000001350A2 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5713396A (en) 1990-06-06 1998-02-03 Asten, Inc. Papermakers fabric with stacked machine and cross machine direction yarns
US6517532B1 (en) 1997-05-15 2003-02-11 Palomar Medical Technologies, Inc. Light energy delivery head
US6273884B1 (en) 1997-05-15 2001-08-14 Palomar Medical Technologies, Inc. Method and apparatus for dermatology treatment
US8182473B2 (en) 1999-01-08 2012-05-22 Palomar Medical Technologies Cooling system for a photocosmetic device
EP1566149A1 (de) 1998-03-12 2005-08-24 Palomar Medical Technologies, Inc. System zur elektromagnetischen Bestrahlung der Haut
DE19926728B4 (de) 1999-06-11 2011-08-18 3M Espe Ag, 82229 Verwendung von Trägermaterialien und diagnostisch nutzbaren Zusatzstoffen in Abbildungsverfahren für intraorale Diagnosezwecke
DE10061195B4 (de) 2000-12-08 2004-12-02 3M Espe Ag Verwendung von Abformmassen zur Herstellung von Behandlungsvorrichtungen
AU2002227838A1 (en) * 2001-01-31 2002-08-12 Eva F. Dickson Method and hand-held device for fluorescence detection
DE10129694C1 (de) * 2001-06-22 2003-02-06 Sirona Dental Systems Gmbh Verfahren und eine Vorrichtung zum Erkennen von krankhaften Veränderungen wie Karies, Plaque, Konkrementen oder bakteriellem Befall an einer Gewebeoberfläche, insbesondere an Zähnen
DE10141161A1 (de) * 2001-08-16 2003-02-27 C & E Fein Gmbh & Co Kg Lichtoptische Kontrolleinrichtung
US7135033B2 (en) 2002-05-23 2006-11-14 Palomar Medical Technologies, Inc. Phototreatment device for use with coolants and topical substances
BR0312430A (pt) 2002-06-19 2005-04-26 Palomar Medical Tech Inc Método e aparelho para tratamento de condições cutâneas e subcutâneas
DE10261241A1 (de) * 2002-12-20 2004-07-15 3M Espe Ag Dentalmaterial mit bakteriostatischen und/oder bakteriziden Substanzen
CN1771073A (zh) 2003-02-10 2006-05-10 帕洛玛医疗技术公司 发光的口腔用具以及使用方法
US20040254478A1 (en) * 2003-05-22 2004-12-16 De Josselin De Jong Elbert Fluorescence filter for tissue examination and imaging
US20050167438A1 (en) * 2004-02-02 2005-08-04 Max Minyayev Secure spill-proof configuration for child training cup
JP4494127B2 (ja) * 2004-08-18 2010-06-30 富士フイルム株式会社 断層画像観察装置、内視鏡装置、及び、それらに用いるプローブ
US7856985B2 (en) 2005-04-22 2010-12-28 Cynosure, Inc. Method of treatment body tissue using a non-uniform laser beam
US20070016173A1 (en) * 2005-07-14 2007-01-18 Michael Kreindel Protective material, clothing item and method of protection
AU2006278255A1 (en) * 2005-08-08 2007-02-15 Palomar Medical Technologies, Inc. Eye-safe photocosmetic device
JP2009509140A (ja) 2005-09-15 2009-03-05 パロマー・メデイカル・テクノロジーズ・インコーポレーテツド 皮膚の光学的判定デバイス
EP1787627A1 (de) * 2005-11-17 2007-05-23 3M Innovative Properties Company Antimikrobielles Zahnabdruckmaterial
KR100798486B1 (ko) * 2006-03-29 2008-01-28 한국전기연구원 형광 진단 및 광역동치료를 위한 광원장치
US8647119B1 (en) 2006-04-18 2014-02-11 President And Fellows Of Harvard College Methods and kits with fluorescent probes for caries detection
US20080038686A1 (en) * 2006-04-18 2008-02-14 Shigemi Nagai Methods and kits for early stage caries detection
US7577284B2 (en) * 2006-04-21 2009-08-18 Carestream Health, Inc. Optical detection of dental caries
WO2008001303A1 (en) * 2006-06-29 2008-01-03 Koninklijke Philips Electronics N.V. A surface detection system for use with a droplet spray oral cleaning device
BRPI0715104A2 (pt) † 2006-07-25 2013-06-04 Procter & Gamble mÉtodos e produtos para analisar tecidos gengivais
US7586957B2 (en) 2006-08-02 2009-09-08 Cynosure, Inc Picosecond laser apparatus and methods for its operation and use
US20080170112A1 (en) * 2007-01-17 2008-07-17 Hull Charles W Build pad, solid image build, and method for building build supports
US20080299517A1 (en) * 2007-06-01 2008-12-04 Delaney Ii Page W Denture with suction attachment
US8738116B2 (en) * 2007-09-21 2014-05-27 National Research Council Of Canada Method and apparatus for periodontal diagnosis
US9326836B2 (en) * 2008-05-31 2016-05-03 Florida Probe Corporation Single use periodontal probe
AU2008357475B2 (en) 2008-06-04 2012-11-01 Colgate-Palmolive Company Oral care implement with cavitation system
US8591227B2 (en) * 2008-10-06 2013-11-26 Jbl Radical Innovations, Llc Mouthpiece that adjusts to user arch sizes and seals from oxygen exposure
DE102009013000A1 (de) * 2009-03-13 2010-09-16 Kaltenbach & Voigt Gmbh Handgerät zur Abgabe einer pastösen Füllmasse
US20100256125A1 (en) * 2009-04-06 2010-10-07 Zila Pharmaceuticals, Inc. Use of improved toluidine blue in photodynamic therapy
KR101062005B1 (ko) * 2009-05-26 2011-09-05 주식회사 두배시스템 배관 검사 장치
US9919168B2 (en) 2009-07-23 2018-03-20 Palomar Medical Technologies, Inc. Method for improvement of cellulite appearance
US9642687B2 (en) 2010-06-15 2017-05-09 The Procter & Gamble Company Methods for whitening teeth
ITBO20110216A1 (it) * 2011-04-21 2012-10-22 Gp Investimenti S R L Apparecchiatura per trattamenti odontoiatrici
US9095296B2 (en) * 2011-11-10 2015-08-04 C. Paxton Designs, Inc. Therapeutic gum irrigator
US9780518B2 (en) 2012-04-18 2017-10-03 Cynosure, Inc. Picosecond laser apparatus and methods for treating target tissues with same
KR101385978B1 (ko) * 2012-08-09 2014-04-16 한국전기연구원 광학 진단 및 광 치료를 위한 복합 광원 장치
LT6038B (lt) 2012-10-22 2014-06-25 I. Į. Lazerių Ir Bangų Medicinos Mokslinė Klinika Onkologinės patologijos sąlygotų audinių skysčių fotodinaminė diagnostika
WO2014145707A2 (en) 2013-03-15 2014-09-18 Cynosure, Inc. Picosecond optical radiation systems and methods of use
US9572645B2 (en) * 2013-08-01 2017-02-21 Jbl Radical Innovations, Llc Closed system mouthpiece with light and heat generation to activate a formulation to increase its volume
PL3442397T3 (pl) 2016-04-13 2021-11-08 Inspektor Research Systems B.V. Dwuczęstotliwościowe badanie stomatologiczne
US10376149B2 (en) * 2017-07-11 2019-08-13 Colgate-Palmolive Company Oral care evaluation system and process
RU180687U1 (ru) * 2017-12-29 2018-06-21 Федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный медицинский университет" Министерства здравоохранения Российской Федерации Инструмент для забора содержимого из пародонтального кармана
WO2019165426A1 (en) 2018-02-26 2019-08-29 Cynosure, Inc. Q-switched cavity dumped sub-nanosecond laser

Citations (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1171206A (fr) * 1957-04-12 1959-01-23 Dispositif vaporisateur-insufflateur perfectionné
US3667454A (en) * 1970-06-12 1972-06-06 Larry W Prince Toothbrush with ultraviolet emitter
SU405555A1 (ru) * 1970-03-05 1973-11-05 Способ лечения пародонтоза и стоматитов
DE2725793A1 (de) * 1976-06-30 1978-01-05 Lpa Les Produits Associes Diagnose-lampe, insbesondere fuer die zahnkontrolle
EP0049905A1 (de) * 1980-10-14 1982-04-21 Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V. Einrichtung zur Messung der Farbe des Zahnfleisches
DE8517634U1 (de) * 1985-06-18 1985-09-05 Siegert, Ralf, Dr., 2000 Hamburg Gerät zur intradentalen Beleuchtung
US4685596A (en) * 1986-04-23 1987-08-11 Risdon Corporation Fluid dispenser
EP0300277A2 (de) * 1987-07-20 1989-01-25 Colgate-Palmolive Company Vorrichtung und Mittel für die Behandlung von Zahnfleisch
US5033961A (en) * 1988-12-14 1991-07-23 Galway Dental Technology Limited Fluid dispenser
US5098291A (en) * 1989-04-14 1992-03-24 Colgate-Palmolive Company Pressurized medicant applicator
RU1792714C (ru) * 1988-07-05 1993-02-07 Днепропетровский медицинский институт Способ лечени периодонтитов
WO1993021992A1 (en) * 1992-04-30 1993-11-11 Institute Of Dental Surgery Laser treatment
WO1994017797A1 (en) * 1993-02-11 1994-08-18 The General Hospital Corporation Photodynamic treatment of synovium
WO1995007077A1 (en) * 1993-09-10 1995-03-16 The Norwegian Radium Hospital Research Foundation Photochemotherapeutic compositions containing 5-aminolevulinic acid
WO1995010243A1 (en) * 1993-10-11 1995-04-20 Bio Bright Corporation Apparatus for treatment of the oral cavity
US5422093A (en) * 1989-07-28 1995-06-06 Queen's University Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US5558518A (en) * 1992-08-10 1996-09-24 Novadent Ltd. Oral hygiene irrigator syringe bulb
US5570182A (en) * 1994-05-27 1996-10-29 Regents Of The University Of California Method for detection of dental caries and periodontal disease using optical imaging
EP0743029A2 (de) * 1995-04-26 1996-11-20 CeramOptec GmbH Zahnärztliche Laservorrichtung zur Reinigungsbehandlung
WO1996039188A1 (en) * 1995-06-05 1996-12-12 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US5620700A (en) * 1990-10-30 1997-04-15 Alza Corporation Injectable drug delivery system and method
DE29705934U1 (de) * 1997-04-03 1997-06-05 Kaltenbach & Voigt Diagnose- und Behandlungsvorrichtung für Zähne
RU2101047C1 (ru) * 1994-08-23 1998-01-10 Александр Алексеевич Прохончуков Способ лечения пародонтитов
WO1998006456A1 (en) * 1996-08-08 1998-02-19 Light Sciences Limited Partnership Method and apparatus to treat gingival and periodontal disease
WO1998009155A1 (en) * 1996-08-27 1998-03-05 Medeikonos Ab Method for detecting cancer on skin of humans and mammals and arrangement for performing the method
WO1998010711A1 (fr) * 1996-09-10 1998-03-19 Grigory Borisovich Altshuler Brosse a dents
WO1998030242A2 (en) * 1997-01-10 1998-07-16 Photocure As Photochemotherapeutic compositions

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3667754A (en) * 1970-10-15 1972-06-06 Ohio Displays Inc Multiple switch amusement projection device and method
US3711700A (en) 1971-05-10 1973-01-16 Gte Sylvania Inc Disclosing light
CA982900A (en) * 1972-07-12 1976-02-03 Barry S. Fichter Water control valve structure
US4184196A (en) 1975-11-28 1980-01-15 Moret Michel A Diagnostic lamp, particularly for checking teeth
DE3270634D1 (en) * 1981-11-12 1986-05-22 John Joseph Jacklich A dental syringe
US4592728A (en) * 1981-12-07 1986-06-03 Davis Dennis R Periodontal lavage delivery system
US4479499A (en) * 1982-01-29 1984-10-30 Alfano Robert R Method and apparatus for detecting the presence of caries in teeth using visible light
US4468197A (en) * 1983-04-26 1984-08-28 Wayne Provost Apparatus and method for detecting cavities
US4553936A (en) * 1984-07-31 1985-11-19 Dentsply Research & Development Corp. Dental impression tray and method of use
US5104392A (en) * 1985-03-22 1992-04-14 Massachusetts Institute Of Technology Laser spectro-optic imaging for diagnosis and treatment of diseased tissue
JPS6397175A (ja) * 1986-10-15 1988-04-27 森　敬 歯茎治療照射光照射装置
US4867682A (en) * 1987-11-13 1989-09-19 Dentsply Research & Development Corp. Dental impression tray
DE68906167T2 (de) * 1988-01-20 1993-08-05 Sunstar Inc Zusammensetzung zur erkennung von paradontalen krankheiten.
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US4950163A (en) * 1988-05-19 1990-08-21 Zimble Alan W Dental syringe for treating gums
US5316473A (en) * 1988-06-17 1994-05-31 Dentsply Research & Development Corp. Light curing apparatus and method
US4883425A (en) * 1988-08-26 1989-11-28 Zimble Alan W Dental probe assembly
US5052927A (en) * 1988-10-24 1991-10-01 Discko John Jr Syringe and disposable capsule with cannula for use therewith
US5955490A (en) * 1989-07-28 1999-09-21 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US20020058008A1 (en) * 1989-07-28 2002-05-16 Kennedy James C. Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US5079262A (en) 1989-07-28 1992-01-07 Queen's University At Kingston Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
FR2660852A1 (fr) * 1990-04-17 1991-10-18 Cheval Freres Sa Instrument dentaire a faisceau laser.
JPH043500A (ja) 1990-04-19 1992-01-08 Mitsubishi Electric Corp 電子部品実装機の吸着ノズル
JPH04299998A (ja) * 1991-03-28 1992-10-23 Lion Corp 口臭菌検査薬
US5382163A (en) * 1992-07-20 1995-01-17 Putnam; David L. Method and apparatus for detecting the presence of dental plaque or calculus
DE4226461C2 (de) * 1992-08-10 1994-10-20 Siemens Ag Zahnärztliches Instrument zur Behandlung von Zähnen mittels Laserstrahlen
US5230624A (en) * 1992-11-09 1993-07-27 Wolf Leo H Water purification system for dental instrument
CA2102884A1 (en) * 1993-03-04 1994-09-05 James J. Wynne Dental procedures and apparatus using ultraviolet radiation
US5409376A (en) * 1993-03-10 1995-04-25 Murphy; Quentin M. Apparatus and process for laser-assisted driling
GB9309397D0 (en) * 1993-05-07 1993-06-23 Patel Bipin C M Laser treatment
US5443386A (en) * 1993-09-07 1995-08-22 Viskup; John H. Toothbrush and method for treatment of periodontal disease
US5442093A (en) * 1994-05-09 1995-08-15 Schering Corporation Process for preparing intermediates for the synthesis of antifungal agents
US5897321A (en) * 1995-07-24 1999-04-27 International Business Machines Corporation Dental procedures and apparatus using ultraviolet radiation
US6350123B1 (en) * 1995-08-31 2002-02-26 Biolase Technology, Inc. Fluid conditioning system
EP0861044B1 (de) * 1995-09-26 2001-03-07 Karl Storz GmbH & Co. KG Vorrichtung zur photodynamischen diagnose
DE19541686B4 (de) * 1995-11-08 2009-08-06 Kaltenbach & Voigt Gmbh & Co. Kg Vorrichtung zum Erkennen von Karies, Plaque oder bakteriellem Befall an Zähnen
US5897509A (en) * 1996-06-21 1999-04-27 Aisin Seiki Kabushiki Kaisha Probe for measuring periodontal pocket depth
JPH1033576A (ja) * 1996-07-23 1998-02-10 Kyoto Kikai Kogu Kk 歯周ポケット測定及び探針用プローブ
JPH10172444A (ja) 1996-12-06 1998-06-26 Fujitsu General Ltd プラズマディスプレイ装置
AU6028598A (en) * 1997-01-09 1998-08-03 Emory University Non-iron metalloporphyrins and methods of use
US6462070B1 (en) * 1997-03-06 2002-10-08 The General Hospital Corporation Photosensitizer conjugates for pathogen targeting
DE19709500C1 (de) * 1997-03-07 1998-07-23 Kaltenbach & Voigt Verfahren und Vorrichtung zum Ermitteln von Karies an Zähnen
DE29704185U1 (de) * 1997-03-07 1997-04-30 Kaltenbach & Voigt Vorrichtung zum Erkennen von Karies, Plaque oder bakteriellem Befall an Zähnen
US5813854A (en) * 1997-04-07 1998-09-29 Nikodem; Stephen G. Orthodontic brace installation device
US5856566A (en) * 1997-09-02 1999-01-05 Dusa Pharmaceuticals, Inc. Sterilized 5-aminolevulinic acid
US20030059471A1 (en) * 1997-12-15 2003-03-27 Compton Bruce Jon Oral delivery formulation
DE19804797A1 (de) * 1998-02-07 1999-08-12 Storz Karl Gmbh & Co Vorrichtung zur endoskopischen Fluoreszenzdiagnose von Gewebe
US5941701A (en) * 1998-07-14 1999-08-24 Ceramoptec Ind Inc Device and method to treat oral disease in felines
US6602274B1 (en) * 1999-01-15 2003-08-05 Light Sciences Corporation Targeted transcutaneous cancer therapy
US6270342B1 (en) * 1999-07-28 2001-08-07 Ceramoptec Industries, Inc. Dental laser treatment hand-piece and system

Patent Citations (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1171206A (fr) * 1957-04-12 1959-01-23 Dispositif vaporisateur-insufflateur perfectionné
SU405555A1 (ru) * 1970-03-05 1973-11-05 Способ лечения пародонтоза и стоматитов
US3667454A (en) * 1970-06-12 1972-06-06 Larry W Prince Toothbrush with ultraviolet emitter
DE2725793A1 (de) * 1976-06-30 1978-01-05 Lpa Les Produits Associes Diagnose-lampe, insbesondere fuer die zahnkontrolle
EP0049905A1 (de) * 1980-10-14 1982-04-21 Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V. Einrichtung zur Messung der Farbe des Zahnfleisches
DE8517634U1 (de) * 1985-06-18 1985-09-05 Siegert, Ralf, Dr., 2000 Hamburg Gerät zur intradentalen Beleuchtung
US4685596A (en) * 1986-04-23 1987-08-11 Risdon Corporation Fluid dispenser
EP0300277A2 (de) * 1987-07-20 1989-01-25 Colgate-Palmolive Company Vorrichtung und Mittel für die Behandlung von Zahnfleisch
RU1792714C (ru) * 1988-07-05 1993-02-07 Днепропетровский медицинский институт Способ лечени периодонтитов
US5033961A (en) * 1988-12-14 1991-07-23 Galway Dental Technology Limited Fluid dispenser
US5098291A (en) * 1989-04-14 1992-03-24 Colgate-Palmolive Company Pressurized medicant applicator
US5422093A (en) * 1989-07-28 1995-06-06 Queen's University Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US5620700A (en) * 1990-10-30 1997-04-15 Alza Corporation Injectable drug delivery system and method
WO1993021992A1 (en) * 1992-04-30 1993-11-11 Institute Of Dental Surgery Laser treatment
US5558518A (en) * 1992-08-10 1996-09-24 Novadent Ltd. Oral hygiene irrigator syringe bulb
WO1994017797A1 (en) * 1993-02-11 1994-08-18 The General Hospital Corporation Photodynamic treatment of synovium
WO1995007077A1 (en) * 1993-09-10 1995-03-16 The Norwegian Radium Hospital Research Foundation Photochemotherapeutic compositions containing 5-aminolevulinic acid
WO1995010243A1 (en) * 1993-10-11 1995-04-20 Bio Bright Corporation Apparatus for treatment of the oral cavity
US5570182A (en) * 1994-05-27 1996-10-29 Regents Of The University Of California Method for detection of dental caries and periodontal disease using optical imaging
RU2101047C1 (ru) * 1994-08-23 1998-01-10 Александр Алексеевич Прохончуков Способ лечения пародонтитов
EP0743029A2 (de) * 1995-04-26 1996-11-20 CeramOptec GmbH Zahnärztliche Laservorrichtung zur Reinigungsbehandlung
WO1996039188A1 (en) * 1995-06-05 1996-12-12 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
WO1998006456A1 (en) * 1996-08-08 1998-02-19 Light Sciences Limited Partnership Method and apparatus to treat gingival and periodontal disease
WO1998009155A1 (en) * 1996-08-27 1998-03-05 Medeikonos Ab Method for detecting cancer on skin of humans and mammals and arrangement for performing the method
WO1998010711A1 (fr) * 1996-09-10 1998-03-19 Grigory Borisovich Altshuler Brosse a dents
WO1998030242A2 (en) * 1997-01-10 1998-07-16 Photocure As Photochemotherapeutic compositions
DE29705934U1 (de) * 1997-04-03 1997-06-05 Kaltenbach & Voigt Diagnose- und Behandlungsvorrichtung für Zähne

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
ACKERMANN G ET AL: "Simulations on the selectivity of 5-aminolaevulinic acid-induced fluorescence in vivo.", J PHOTOCHEM PHOTOBIOL B, DEC 1998, VOL. 47, NO. 2-3, PAGE(S) 121-8, XP002120202, ISSN: 1011-1344 *
BAUMGARTNER R ET AL: "Inhalation of 5-aminolevulinic acid: a new technique for fluorescence detection of early stage lung cancer.", J PHOTOCHEM PHOTOBIOL B, NOV 1996, VOL. 36, NO. 2, PAGE(S) 169-74, XP002120199, ISSN: 1011-1344 *
DATABASE WPI Section Ch Week 199424, Derwent World Patents Index; Class B05, AN 1994-197879, XP002132813 *
DATABASE WPI Section PQ Week 197505, Derwent World Patents Index; Class P34, AN 1975-B2816W, XP002132814 *
DATABASE WPI Section PQ Week 199834, Derwent World Patents Index; Class P34, AN 1998-396648, XP002132812 *
LEUNIG A. ET AL: "PHOTODYNAMISCHE DIAGNOSTIK VON NEOPLASIEN DER MUNDHÖHLE NACH LOKALER APPLIKATION VON 5-AMINOLÄVULINSÄURE", LARYNGO- RHINO- OTOLOGIE, 1996, VOL. 75, NO. 8, PAGE(S) 459-464, XP002120196 *
LEUNIG, ANDREAS ET AL: "Fluorescence imaging and spectroscopy of 5- aminolevulinic acid induced protoporphyrin IX for the detection of neoplastic lesions in the oral cavity", AM. J. SURG., 1996, VOL. 172, NO. 6, PAGE(S) 674-677, XP002120195 *
MESSMANN H ET AL: "Photodynamische Diagnostik gastrointestinaler Prakanzerosen nach Sensibilisierung mit 5-Aminolavulinsaure. Eine Pilotstudie.", DTSCH MED WOCHENSCHR, 24-4-1998, VOL. 123, NO. 17, PAGE(S) 515-21, XP002120197 *
PENG Q ET AL: "5-Aminolevulinic acid-based photodynamic therapy. Clinical research and future challenges.", CANCER, JUN 15 1997, VOL. 79, NO. 12, PAGE(S) 2282-308, XP002120201, ISSN: 0008-543X *
ROPER J.M. ET AL: "Tetrapyrrole biosynthesis in several haem-dependent anaerobic pathogens", REVIEWS IN MEDICAL MICROBIOLOGY, 1997, VOL. 8, NO. SUPPL. 1, PAGE(S) S13-S17, XP002120198 *
VONARX V ET AL: "Potential efficacy of a delta 5-aminolevulinic acid bioadhesive gel formulation for the photodynamic treatment of lesions of the gastrointestinal tract in mice.", J PHARM PHARMACOL, JUL 1997, VOL. 49, NO. 7, PAGE(S) 652-6, XP002078605, ISSN: 0022-3573 *
W.E. GRANT ET AL.: "Photodynamic therapy of oral cancer: photosensitisation with systemic aminolaevulinic acid", THE LANCET, vol. 342, 17 July 1993 (1993-07-17), LANCET LIMITED. LONDON., GB, pages 147 - 148, XP002132811, ISSN: 0140-6736 *
WEBBER J ET AL: "On-line fluorescence of human tissues after oral administration of 5-aminolevulinic acid.", J PHOTOCHEM PHOTOBIOL B, APR 1997, VOL. 38, NO. 2-3, PAGE(S) 209-14, XP002120200, ISSN: 1011-1344 *

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AU4372599A (en) 2000-01-24
US20040248062A1 (en) 2004-12-09
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US6860879B2 (en) 2005-03-01
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