WO2000002999A2 - Medium and matrix for long-term proliferation of cells - Google Patents
Medium and matrix for long-term proliferation of cells Download PDFInfo
- Publication number
- WO2000002999A2 WO2000002999A2 PCT/US1999/015464 US9915464W WO0002999A2 WO 2000002999 A2 WO2000002999 A2 WO 2000002999A2 US 9915464 W US9915464 W US 9915464W WO 0002999 A2 WO0002999 A2 WO 0002999A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cells
- amino acids
- polar amino
- culture medium
- cell culture
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
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- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Cardiology (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Prostheses (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU49772/99A AU758833B2 (en) | 1998-07-10 | 1999-07-09 | Medium and matrix for long-term proliferation of cells |
EP99933791A EP1098959A2 (en) | 1998-07-10 | 1999-07-09 | Medium and matrix for long-term proliferation of cells |
JP2000559221A JP2002520013A (en) | 1998-07-10 | 1999-07-09 | Medium and substrate for long-term cell growth |
CA2332701A CA2332701C (en) | 1998-07-10 | 1999-07-09 | Medium and matrix for long-term proliferation of cells |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/113,437 US6231881B1 (en) | 1992-02-24 | 1998-07-10 | Medium and matrix for long-term proliferation of cells |
US09/113,437 | 1998-07-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000002999A2 true WO2000002999A2 (en) | 2000-01-20 |
WO2000002999A3 WO2000002999A3 (en) | 2000-04-20 |
Family
ID=22349408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/015464 WO2000002999A2 (en) | 1998-07-10 | 1999-07-09 | Medium and matrix for long-term proliferation of cells |
Country Status (9)
Country | Link |
---|---|
US (5) | US6231881B1 (en) |
EP (1) | EP1098959A2 (en) |
JP (1) | JP2002520013A (en) |
AT (2) | ATE326243T1 (en) |
AU (1) | AU758833B2 (en) |
CA (1) | CA2332701C (en) |
DE (1) | DE69941707D1 (en) |
ES (1) | ES2337320T3 (en) |
WO (1) | WO2000002999A2 (en) |
Cited By (8)
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WO2001019962A2 (en) * | 1999-09-15 | 2001-03-22 | Encelle, Inc. | Method of preserving tissue viability during mechanical separation process |
US6703017B1 (en) | 1994-04-28 | 2004-03-09 | Ixion Biotechnology, Inc. | Reversal of insulin-dependent diabetes by islet-producing stem cells, islet progenitor cells and islet-like structures |
JP2005528933A (en) * | 2002-02-21 | 2005-09-29 | エンセル,インコーポレイテッド | Cross-linked bioactive hydrogel matrix |
US6992062B2 (en) | 2000-05-31 | 2006-01-31 | Encelle, Inc. | Method of stimulation hair growth |
US7156877B2 (en) | 2001-06-29 | 2007-01-02 | The Regents Of The University Of California | Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs |
WO2008051243A2 (en) | 2005-11-30 | 2008-05-02 | Massachusetts Institute Of Technology | Pathogen-detecting cell preservation systems |
US9616046B2 (en) | 2013-06-28 | 2017-04-11 | Japan Bio Products Co., Ltd. | Hepatocyte-proliferating agent |
WO2019021143A1 (en) * | 2017-07-22 | 2019-01-31 | Rangasamy Naidu Educational Trust | L- histidine molecule based hydrogel |
Families Citing this family (88)
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US7070607B2 (en) * | 1998-01-27 | 2006-07-04 | The Regents Of The University Of California | Bioabsorbable polymeric implants and a method of using the same to create occlusions |
US6905707B2 (en) * | 1998-05-28 | 2005-06-14 | Medical Research Institute | Controlled release arginine alpha ketoglutarate |
EP1025861A1 (en) * | 1999-02-04 | 2000-08-09 | Roche Diagnostics GmbH | Pharmaceutical compositions of hydrophobically modified Hedgehog Proteins and their use |
US20090047325A1 (en) * | 1999-04-30 | 2009-02-19 | Neurotrophincell Pty. Limited | Xenotransplant for cns therapy |
US20050265977A1 (en) * | 1999-04-30 | 2005-12-01 | Elliott Robert B | Xenotransplant for CNS therapy |
ATE468122T1 (en) * | 1999-04-30 | 2010-06-15 | Neurotrophincell Pty Ltd | XENOTRANSPLANT FOR CNS THERAPY |
AU780366B2 (en) * | 2000-01-20 | 2005-03-17 | Diatranz Otsuka Limited | Preparation and xenotransplantation of porcine islets |
WO2002032437A1 (en) * | 2000-10-17 | 2002-04-25 | Diatranz Limited | Preparation and xenotransplantation or porcine islets |
US20020188170A1 (en) * | 2001-04-27 | 2002-12-12 | Santamore William P. | Prevention of myocardial infarction induced ventricular expansion and remodeling |
AU2002315027A1 (en) * | 2001-05-15 | 2002-11-25 | Children's Medical Center Corporation | Methods and apparatus for application of micro-mechanical forces to tissues |
US20040097401A1 (en) * | 2002-11-14 | 2004-05-20 | Debatosh Datta | Lysine in therapeutic angiogenesis, particularly in treating ischaemic conditions |
US6702744B2 (en) | 2001-06-20 | 2004-03-09 | Advanced Cardiovascular Systems, Inc. | Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery |
US6790455B2 (en) * | 2001-09-14 | 2004-09-14 | The Research Foundation At State University Of New York | Cell delivery system comprising a fibrous matrix and cells |
US8608661B1 (en) | 2001-11-30 | 2013-12-17 | Advanced Cardiovascular Systems, Inc. | Method for intravascular delivery of a treatment agent beyond a blood vessel wall |
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Also Published As
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CA2332701C (en) | 2010-04-20 |
ES2337320T3 (en) | 2010-04-22 |
US6713079B2 (en) | 2004-03-30 |
US6231881B1 (en) | 2001-05-15 |
ATE326243T1 (en) | 2006-06-15 |
US6315994B2 (en) | 2001-11-13 |
US20010010826A1 (en) | 2001-08-02 |
AU758833B2 (en) | 2003-04-03 |
DE69941707D1 (en) | 2010-01-07 |
US20010019841A1 (en) | 2001-09-06 |
ATE449619T1 (en) | 2009-12-15 |
JP2002520013A (en) | 2002-07-09 |
AU4977299A (en) | 2000-02-01 |
EP1098959A2 (en) | 2001-05-16 |
CA2332701A1 (en) | 2000-01-20 |
WO2000002999A3 (en) | 2000-04-20 |
US6261587B1 (en) | 2001-07-17 |
US20010007658A1 (en) | 2001-07-12 |
US6730315B2 (en) | 2004-05-04 |
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