WO2000011171A3 - Human rna-associated proteins - Google Patents

Human rna-associated proteins Download PDF

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Publication number
WO2000011171A3
WO2000011171A3 PCT/US1999/019361 US9919361W WO0011171A3 WO 2000011171 A3 WO2000011171 A3 WO 2000011171A3 US 9919361 W US9919361 W US 9919361W WO 0011171 A3 WO0011171 A3 WO 0011171A3
Authority
WO
WIPO (PCT)
Prior art keywords
associated proteins
human rna
rnaap
provides
expression
Prior art date
Application number
PCT/US1999/019361
Other languages
French (fr)
Other versions
WO2000011171A2 (en
Inventor
Jennifer L Hillman
Henry Yue
Y Tom Tang
Neil C Corley
Karl J Guegler
Gina A Gorgone
Chandra Patterson
Mariah R Baughn
Preeti Lal
Olga Bandman
Roopa Reddy
Yalda Azimzai
Leo L Shih
Junming Yang
Dyung Aina M Lu
Original Assignee
Incyte Pharma Inc
Jennifer L Hillman
Henry Yue
Y Tom Tang
Neil C Corley
Karl J Guegler
Gina A Gorgone
Chandra Patterson
Mariah R Baughn
Preeti Lal
Olga Bandman
Roopa Reddy
Yalda Azimzai
Leo L Shih
Junming Yang
Dyung Aina M Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Jennifer L Hillman, Henry Yue, Y Tom Tang, Neil C Corley, Karl J Guegler, Gina A Gorgone, Chandra Patterson, Mariah R Baughn, Preeti Lal, Olga Bandman, Roopa Reddy, Yalda Azimzai, Leo L Shih, Junming Yang, Dyung Aina M Lu filed Critical Incyte Pharma Inc
Priority to CA002340277A priority Critical patent/CA2340277A1/en
Priority to AU56903/99A priority patent/AU5690399A/en
Priority to JP2000566425A priority patent/JP2002523045A/en
Priority to EP99943897A priority patent/EP1109903A2/en
Publication of WO2000011171A2 publication Critical patent/WO2000011171A2/en
Publication of WO2000011171A3 publication Critical patent/WO2000011171A3/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • AIDS & HIV (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)

Abstract

The invention provides human RNA-associated proteins (RNAAP) and polynucleotides which identify and encode RNAAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with the expression of RNAAP.
PCT/US1999/019361 1998-08-21 1999-08-20 Human rna-associated proteins WO2000011171A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002340277A CA2340277A1 (en) 1998-08-21 1999-08-20 Human rna-associated proteins
AU56903/99A AU5690399A (en) 1998-08-21 1999-08-20 Human rna-associated proteins
JP2000566425A JP2002523045A (en) 1998-08-21 1999-08-20 Human RNA-related protein
EP99943897A EP1109903A2 (en) 1998-08-21 1999-08-20 Human rna-associated proteins

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9755098P 1998-08-21 1998-08-21
US11563999P 1999-01-12 1999-01-12
US60/115,639 1999-01-12
US60/097,550 1999-01-12

Publications (2)

Publication Number Publication Date
WO2000011171A2 WO2000011171A2 (en) 2000-03-02
WO2000011171A3 true WO2000011171A3 (en) 2000-07-27

Family

ID=26793399

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/019361 WO2000011171A2 (en) 1998-08-21 1999-08-20 Human rna-associated proteins

Country Status (4)

Country Link
EP (1) EP1109903A2 (en)
JP (1) JP2002523045A (en)
CA (1) CA2340277A1 (en)
WO (1) WO2000011171A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6808876B1 (en) * 2000-05-02 2004-10-26 Immusol, Inc. Cellular regulators of infectious agents and methods of use
AU2002326372A1 (en) * 2001-07-12 2003-01-29 Incyte Genomics, Inc. Nucleic acid-associated proteins
JP2003061664A (en) * 2001-08-21 2003-03-04 Japan Science & Technology Corp Rna-binding protein musashi2
WO2019202767A1 (en) * 2018-04-17 2019-10-24 国立大学法人大阪大学 Antifibrotic agent and biomarker for fibrosis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679716A1 (en) * 1993-11-12 1995-11-02 Kenichi Matsubara Gene signature
US5561222A (en) * 1989-11-15 1996-10-01 Duke University RNA-binding proteins useful for the control of cellular genetic processing and expression
WO1998023744A1 (en) * 1996-11-26 1998-06-04 Incyte Pharmaceuticals, Inc. Novel human rna-binding protein

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5561222A (en) * 1989-11-15 1996-10-01 Duke University RNA-binding proteins useful for the control of cellular genetic processing and expression
EP0679716A1 (en) * 1993-11-12 1995-11-02 Kenichi Matsubara Gene signature
WO1998023744A1 (en) * 1996-11-26 1998-06-04 Incyte Pharmaceuticals, Inc. Novel human rna-binding protein

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMHUM1 E.M.B.L. Databases; 17 March 1998 (1998-03-17), YANG L ET AL: "Homo sapiens TLS-associated protein TASR mRNA, complete cds", XP002128498 *
DATABASE GENESEQ E.M.B.L. Databases; 4 July 1996 (1996-07-04), MATSUBARA K ET AL: "Human gene signature HUMGS00127", XP002128499 *
YANG L ET AL: "Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing", JOURNAL OF BIOLOGICAL CHEMISTRY., vol. 273, no. 43, 23 October 1998 (1998-10-23), pages 27761 - 27764, XP002128497 *

Also Published As

Publication number Publication date
WO2000011171A2 (en) 2000-03-02
CA2340277A1 (en) 2000-03-02
JP2002523045A (en) 2002-07-30
EP1109903A2 (en) 2001-06-27

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