WO2000015788A3 - Dna sequence encoding oncofetal ferritin protein - Google Patents

Dna sequence encoding oncofetal ferritin protein Download PDF

Info

Publication number
WO2000015788A3
WO2000015788A3 PCT/IL1999/000485 IL9900485W WO0015788A3 WO 2000015788 A3 WO2000015788 A3 WO 2000015788A3 IL 9900485 W IL9900485 W IL 9900485W WO 0015788 A3 WO0015788 A3 WO 0015788A3
Authority
WO
WIPO (PCT)
Prior art keywords
dna sequence
sequence encoding
ferritin protein
encoding oncofetal
oncofetal ferritin
Prior art date
Application number
PCT/IL1999/000485
Other languages
French (fr)
Other versions
WO2000015788A2 (en
Inventor
Chaya Moroz
Original Assignee
Gardino Investment N V
Chaya Moroz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gardino Investment N V, Chaya Moroz filed Critical Gardino Investment N V
Priority to AU56457/99A priority Critical patent/AU5645799A/en
Priority to US09/786,867 priority patent/US7217686B1/en
Priority to JP2000570315A priority patent/JP2003512811A/en
Priority to EP99943188A priority patent/EP1112358A2/en
Publication of WO2000015788A2 publication Critical patent/WO2000015788A2/en
Publication of WO2000015788A3 publication Critical patent/WO2000015788A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

A DNA sequence coding for oncofetal ferritin 1 (OFF1) as well as an amino acid sequence encoded by the DNA sequence. Pharmaceutical compositions may be prepared comprising the above sequences for treating various diseases, for facilitating transplantations and for treating pathological pregnancies.
PCT/IL1999/000485 1998-09-11 1999-09-08 Dna sequence encoding oncofetal ferritin protein WO2000015788A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU56457/99A AU5645799A (en) 1998-09-11 1999-09-08 Dna sequence encoding oncofetal ferritin protein
US09/786,867 US7217686B1 (en) 1999-09-08 1999-09-08 DNA sequence encoding oncofetal ferritin protein
JP2000570315A JP2003512811A (en) 1998-09-11 1999-09-08 DNA sequence encoding oncofetal ferritin protein
EP99943188A EP1112358A2 (en) 1998-09-11 1999-09-08 Dna sequence encoding oncofetal ferritin protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL126181 1998-09-11
IL12618198A IL126181A0 (en) 1998-09-11 1998-09-11 Dna sequences proteins coded by them medicaments and detection methods using same

Publications (2)

Publication Number Publication Date
WO2000015788A2 WO2000015788A2 (en) 2000-03-23
WO2000015788A3 true WO2000015788A3 (en) 2000-05-25

Family

ID=11071957

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL1999/000485 WO2000015788A2 (en) 1998-09-11 1999-09-08 Dna sequence encoding oncofetal ferritin protein

Country Status (5)

Country Link
EP (1) EP1112358A2 (en)
JP (1) JP2003512811A (en)
AU (1) AU5645799A (en)
IL (1) IL126181A0 (en)
WO (1) WO2000015788A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989009936A1 (en) * 1988-04-08 1989-10-19 Chaya Moroz Isoferritin as a marker for pathological pregnancy
US4882270A (en) * 1981-05-15 1989-11-21 Chaya Moroz Monoclonal antibodies to placental isoferritin for use in detecting oncofetal ferritin associated with breast cancer and Hodgkins disease
EP0426458A2 (en) * 1989-10-31 1991-05-08 Japan Antibiotics Research Association Human monocyte growth factor
JPH0731482A (en) * 1993-07-21 1995-02-03 Life Technol Kenkyusho Recombined growth factor for human monocyte, and dna sequence coding the same
US5571678A (en) * 1981-05-15 1996-11-05 Moroz; Chaya Placental isoferritins for the prognosis and diagnosis of immunosuppression

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4882270A (en) * 1981-05-15 1989-11-21 Chaya Moroz Monoclonal antibodies to placental isoferritin for use in detecting oncofetal ferritin associated with breast cancer and Hodgkins disease
US5571678A (en) * 1981-05-15 1996-11-05 Moroz; Chaya Placental isoferritins for the prognosis and diagnosis of immunosuppression
WO1989009936A1 (en) * 1988-04-08 1989-10-19 Chaya Moroz Isoferritin as a marker for pathological pregnancy
EP0426458A2 (en) * 1989-10-31 1991-05-08 Japan Antibiotics Research Association Human monocyte growth factor
JPH0731482A (en) * 1993-07-21 1995-02-03 Life Technol Kenkyusho Recombined growth factor for human monocyte, and dna sequence coding the same

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
BOYD D ET AL.: "Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 260, no. 21, 25 September 1985 (1985-09-25), pages 11755 - 11761, XP000876843 *
DATABASE EMORG EMBL; 9 June 1982 (1982-06-09), ANDERSON S ET AL.: "H. sapiens mitochondrial genome", XP002131126 *
DATABASE GCG_GENESEQ_P Geneseq; 1 November 1995 (1995-11-01), ZH LIFE TECHNOLOGY KENKYUSHO: "Human monocyte growth factor", XP002131125 *
FISCH B ET AL.: "Placental isoferritin as a marker of early abortion in pregnancies induced by in vitro fertilization", PLACENTA, vol. 17, no. 4, May 1996 (1996-05-01), pages 247 - 251, XP000877132 *
GARTY B Z ET AL.: "High serum levels of placental isoferritin p43 component in Down syndrome.", CHILDREN'S HOSPITAL QUARTERLY, vol. 10, no. 1, 1998, pages 39 - 41, XP000876978 *
HIGGY N A ET AL: "Differential expression of human ferritin H chain gene in immortal human breast epithelial MCF-10F cells", MOLECULAR CARCINOGENESIS, vol. 20, no. 4, December 1997 (1997-12-01), pages 332 - 339, XP000876881 *
MAYMON R ET AL.: "Placental isoferritin: a new biomarker from conception to delivery", BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, vol. 103, no. 4, April 1996 (1996-04-01), pages 301 - 305, XP000877134 *
MOROZ C ET AL: "T-cell mitogenesis stimulates the synthesis of a mRNA species coding for a 43-kDa peptide reactive with CM-H-9, a monoclonal antibody specific for placental isoferritin.", PROC. NATL. ACAD. SCI. USA, vol. 86, no. 9, May 1989 (1989-05-01), pages 3282 - 3285, XP002131123 *
PATENT ABSTRACTS OF JAPAN *
ROSEN H R: "Placental isoferritin-associated p43 in pregnancy and breast cancer. Minireview.", NEOPLASMA, vol. 43, no. 6, 1996, pages 357 - 362, XP000876880 *
YANIV I ET AL: "p43, a new placental isoferritin subunit, is a growth factor for granulocyte-monocyte progenitor cells", BONE MARROW TRANSPLANTATION, vol. 23, no. suppl. 1, March 1999 (1999-03-01), pages S83 (272), XP000876882 *

Also Published As

Publication number Publication date
EP1112358A2 (en) 2001-07-04
WO2000015788A2 (en) 2000-03-23
IL126181A0 (en) 1999-05-09
JP2003512811A (en) 2003-04-08
AU5645799A (en) 2000-04-03

Similar Documents

Publication Publication Date Title
EP1131333A4 (en) ISOLATED NUCLEIC ACID MOLECULES WHICH ENCODE T CELL INDUCIBLE FACTORS (TIFs), THE PROTEINS ENCODED, AND USES THEREOF
ZA988392B (en) Tie ligand homologues.
SI0917571T1 (en) Agouti-related gene
WO2001079462A3 (en) Nucleic acids encoding polypeptides having haloperoxidase activity
WO2001053312A8 (en) Novel nucleic acids and polypeptides
WO2001053455A3 (en) Novel nucleic acids and polypeptides
WO2001079464A3 (en) Nucleic acids encoding polypeptides having haloperoxidase activity
AUPP051497A0 (en) Antimicrobial peptides
AU2002217010A1 (en) Peptides, the production and use thereof for binding immunoglobulins
WO2000027875A3 (en) Activity dependent neurotrophic factor iii (adnf iii)
WO2001055178A3 (en) Liv-1 related protein, polynucleotides encoding the same and use thereof for treatment of cancer
WO2002101052A3 (en) Salutaridinol 7-o-acetyltransferase and derivatives thereof
WO2003022868A3 (en) Metal binding proteins and associated methods
WO1995030001A3 (en) Novel p-selectin ligand protein
WO2000015788A3 (en) Dna sequence encoding oncofetal ferritin protein
WO1998024896A3 (en) Muteins of obese protein
EP0645454A3 (en) Chimeric somatostatin containing protein and coding DNA, immunogenic compositions and method for increasing farm animal productivity.
WO2001053453A3 (en) Novel bone marrow nucleic acids and polypeptides
AU2043597A (en) Human taki dna encoding the same
WO2000000506A3 (en) Human proteins having hydrophobic domains and dnas encoding these proteins
WO2001092468A3 (en) Novel compositions for the expression of the human peptide histidine transporter 1 and methods of use thereof
AU5882998A (en) Nucleic acid sequences encoding citrate transporter proteins
WO2005105838A3 (en) Ion channel
EP0803571A3 (en) Tab1 protein & dna coding therefor
EP1045914B8 (en) Testis-specific human svph1-8 proteinase

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
ENP Entry into the national phase

Ref country code: JP

Ref document number: 2000 570315

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 1999943188

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1999943188

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: 09786867

Country of ref document: US