WO2000017413A3 - Formation of combinatorial arrays of materials using solution-based methodologies - Google Patents

Formation of combinatorial arrays of materials using solution-based methodologies Download PDF

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Publication number
WO2000017413A3
WO2000017413A3 PCT/US1999/021685 US9921685W WO0017413A3 WO 2000017413 A3 WO2000017413 A3 WO 2000017413A3 US 9921685 W US9921685 W US 9921685W WO 0017413 A3 WO0017413 A3 WO 0017413A3
Authority
WO
WIPO (PCT)
Prior art keywords
materials
solution
formation
based methodologies
combinatorial arrays
Prior art date
Application number
PCT/US1999/021685
Other languages
French (fr)
Other versions
WO2000017413A2 (en
WO2000017413B1 (en
Inventor
Daniel Giaquinta
Martin Devenney
Keith Anthony Hall
Isy Goldwasser
Original Assignee
Symyx Technologies Inc
Daniel Giaquinta
Martin Devenney
Keith Anthony Hall
Isy Goldwasser
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Symyx Technologies Inc, Daniel Giaquinta, Martin Devenney, Keith Anthony Hall, Isy Goldwasser filed Critical Symyx Technologies Inc
Priority to AU62552/99A priority Critical patent/AU6255299A/en
Priority to DE69917914T priority patent/DE69917914T2/en
Priority to EP99949737A priority patent/EP1113991B1/en
Priority to AT99949737T priority patent/ATE268735T1/en
Publication of WO2000017413A2 publication Critical patent/WO2000017413A2/en
Publication of WO2000017413A3 publication Critical patent/WO2000017413A3/en
Publication of WO2000017413B1 publication Critical patent/WO2000017413B1/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B13/00Oxygen; Ozone; Oxides or hydroxides in general
    • C01B13/14Methods for preparing oxides or hydroxides in general
    • C01B13/18Methods for preparing oxides or hydroxides in general by thermal decomposition of compounds, e.g. of salts or hydroxides
    • C01B13/185Preparing mixtures of oxides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00351Means for dispensing and evacuation of reagents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/0059Sequential processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00592Split-and-pool, mix-and-divide processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00599Solution-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00646Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
    • B01J2219/0065Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of liquid beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068Means for controlling the apparatus of the process
    • B01J2219/00702Processes involving means for analysing and characterising the products
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/00745Inorganic compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/00745Inorganic compounds
    • B01J2219/0075Metal based compounds
    • B01J2219/00754Metal oxides
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/18Libraries containing only inorganic compounds or inorganic materials
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/08Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Abstract

A combinatorial method for discovering or optimizing materials is disclosed. The method uses solution-based components that are mixed and dispensed into regions on a substrate for drying and/or heat-treating. The drying and/or heat-treating produces materials that can be tested for a desired property.
PCT/US1999/021685 1998-09-18 1999-09-17 Formation of combinatorial arrays of materials using solution-based methodologies WO2000017413A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU62552/99A AU6255299A (en) 1998-09-18 1999-09-17 Formation of combinatorial arrays of materials using solution-based methodologies
DE69917914T DE69917914T2 (en) 1998-09-18 1999-09-17 PRODUCTION OF COMBINATIONAL ARRAYS OF MATERIALS BY METHODS OF SYNTHESIS IN SOLUTION
EP99949737A EP1113991B1 (en) 1998-09-18 1999-09-17 Formation of combinatorial arrays of materials using solution-based methodologies
AT99949737T ATE268735T1 (en) 1998-09-18 1999-09-17 PRODUCTION OF COMBINATORY ARRAYS OF MATERIALS BY METHODS OF SYNTHESIS IN SOLUTION

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15682798A 1998-09-18 1998-09-18
US09/156,827 1998-09-18

Publications (3)

Publication Number Publication Date
WO2000017413A2 WO2000017413A2 (en) 2000-03-30
WO2000017413A3 true WO2000017413A3 (en) 2000-08-17
WO2000017413B1 WO2000017413B1 (en) 2001-05-25

Family

ID=22561259

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/021685 WO2000017413A2 (en) 1998-09-18 1999-09-17 Formation of combinatorial arrays of materials using solution-based methodologies

Country Status (6)

Country Link
US (1) US6828096B1 (en)
EP (1) EP1113991B1 (en)
AT (1) ATE268735T1 (en)
AU (1) AU6255299A (en)
DE (1) DE69917914T2 (en)
WO (1) WO2000017413A2 (en)

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US7491677B2 (en) * 1999-01-15 2009-02-17 Basf Catalysts Llc Combinatorial synthesis
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US6572828B1 (en) 1999-07-16 2003-06-03 General Electric Company Method and apparatus for high-throughput chemical screening
US6770482B1 (en) * 1999-07-16 2004-08-03 General Electric Method and apparatus for rapid screening of multiphase reactions
US7448258B2 (en) 1999-10-29 2008-11-11 Avery Dennison Corporation High throughput screening for moisture barrier characteristics of materials
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DE60108482T2 (en) 2000-03-07 2006-02-16 Symyx Technologies, Inc., Santa Clara PROCESS OPTIMIZING REACTOR WITH PARALLEL FLOW
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US6642061B2 (en) 2000-09-25 2003-11-04 Picoliter Inc. Use of immiscible fluids in droplet ejection through application of focused acoustic energy
DE60126110T2 (en) * 2000-09-25 2007-07-05 Picoliter, Inc., Sunnyvale FOCUSED SOIL ENERGY METHOD AND APPARATUS FOR PRODUCING DROPS OF TWO MIXABLE LIQUIDS
US6548308B2 (en) 2000-09-25 2003-04-15 Picoliter Inc. Focused acoustic energy method and device for generating droplets of immiscible fluids
DE10059328C2 (en) * 2000-11-29 2003-08-14 Siemens Ag Process for creating a structured material library
US7118917B2 (en) 2001-03-07 2006-10-10 Symyx Technologies, Inc. Parallel flow reactor having improved thermal control
US6869551B2 (en) 2001-03-30 2005-03-22 Picoliter Inc. Precipitation of solid particles from droplets formed using focused acoustic energy
DE10121103A1 (en) * 2001-04-27 2002-10-31 Bayer Ag Parallel reactor with gassing cassette for testing heterogeneous catalysts
FR2829770A1 (en) * 2001-09-17 2003-03-21 Centre Nat Rech Scient Preparing precursor component of luminophoric powder or crystals in form of aerogel comprises adding organic solvent, mixing under agitation, and eliminating solvent by drying in autoclave
US20050008828A1 (en) * 2002-07-25 2005-01-13 Trustees Of Stevens Institute Of Technology Patterned polymer microgel and method of forming same
CA2511016A1 (en) 2002-12-20 2004-07-15 Honda Giken Kogyo Kabushiki Kaisha Methods for the preparation of catalysts for hydrogen generation
US20040152127A1 (en) * 2003-02-04 2004-08-05 General Electric Company Photosensitive materials and method for accelerated development of photosensitive materials with tailored properties for tagging of optical media articles
US7134459B2 (en) 2003-06-12 2006-11-14 Symyx Technologies, Inc. Methods and apparatus for mixing powdered samples
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Also Published As

Publication number Publication date
US6828096B1 (en) 2004-12-07
DE69917914D1 (en) 2004-07-15
EP1113991A2 (en) 2001-07-11
WO2000017413A2 (en) 2000-03-30
DE69917914T2 (en) 2004-11-04
AU6255299A (en) 2000-04-10
WO2000017413B1 (en) 2001-05-25
ATE268735T1 (en) 2004-06-15
EP1113991B1 (en) 2004-06-09

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