WO2000029582A3 - Cell surface receptor antigen vaccines - Google Patents

Cell surface receptor antigen vaccines Download PDF

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Publication number
WO2000029582A3
WO2000029582A3 PCT/US1999/027404 US9927404W WO0029582A3 WO 2000029582 A3 WO2000029582 A3 WO 2000029582A3 US 9927404 W US9927404 W US 9927404W WO 0029582 A3 WO0029582 A3 WO 0029582A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell surface
surface receptor
receptor antigen
vaccines
antigen vaccines
Prior art date
Application number
PCT/US1999/027404
Other languages
French (fr)
Other versions
WO2000029582A2 (en
WO2000029582A8 (en
Inventor
Nathalie B Scholler
Mary L Disis
Ingegerd Hellstrom
Karl Erik Hellstrom
Original Assignee
Pacific Northwest Research Ins
Nathalie B Scholler
Mary L Disis
Ingegerd Hellstrom
Karl Erik Hellstrom
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pacific Northwest Research Ins, Nathalie B Scholler, Mary L Disis, Ingegerd Hellstrom, Karl Erik Hellstrom filed Critical Pacific Northwest Research Ins
Priority to EP99965005A priority Critical patent/EP1131432A2/en
Priority to CA002351729A priority patent/CA2351729A1/en
Priority to JP2000582565A priority patent/JP2002530294A/en
Priority to AU31015/00A priority patent/AU3101500A/en
Publication of WO2000029582A2 publication Critical patent/WO2000029582A2/en
Publication of WO2000029582A3 publication Critical patent/WO2000029582A3/en
Publication of WO2000029582A8 publication Critical patent/WO2000029582A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides

Abstract

The invention provides compositions and methods directed to cell surface receptor antigen specific vaccines. More specifically, vaccines are provided that induce or enhance host antibody titers specific for cell surface receptor antigens and that include recombinant expression constructs containing nucleic acids encoding a target cell surface receptor antigen and one or more immune response altering molecules, or the expressed products themselves.
PCT/US1999/027404 1998-11-18 1999-11-17 Cell surface receptor antigen vaccines WO2000029582A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99965005A EP1131432A2 (en) 1998-11-18 1999-11-17 Cell surface receptor antigen vaccines
CA002351729A CA2351729A1 (en) 1998-11-18 1999-11-17 Cell surface receptor antigen vaccines
JP2000582565A JP2002530294A (en) 1998-11-18 1999-11-17 Cell surface receptor antigen vaccine
AU31015/00A AU3101500A (en) 1998-11-18 1999-11-17 Surface receptor antigen vaccines

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10910698P 1998-11-18 1998-11-18
US60/109,106 1998-11-18
US09/441,411 US6734172B2 (en) 1998-11-18 1999-11-16 Surface receptor antigen vaccines
US09/441,411 1999-11-16

Publications (3)

Publication Number Publication Date
WO2000029582A2 WO2000029582A2 (en) 2000-05-25
WO2000029582A3 true WO2000029582A3 (en) 2000-10-12
WO2000029582A8 WO2000029582A8 (en) 2001-03-01

Family

ID=26806620

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/027404 WO2000029582A2 (en) 1998-11-18 1999-11-17 Cell surface receptor antigen vaccines

Country Status (5)

Country Link
US (2) US6734172B2 (en)
EP (1) EP1131432A2 (en)
JP (1) JP2002530294A (en)
CA (1) CA2351729A1 (en)
WO (1) WO2000029582A2 (en)

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US10517875B2 (en) 2014-07-23 2019-12-31 Mayo Foundation for Medical Engineering and Research Targeting DNA-PKcs and B7-H1 to treat cancer
CN113456812A (en) 2015-01-09 2021-10-01 埃图比克斯公司 Methods and compositions for combination immunotherapy
JP2018502922A (en) 2015-01-09 2018-02-01 イーチュービクス コーポレイション Methods and compositions for Ebola virus vaccination
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US11464839B2 (en) 2015-12-04 2022-10-11 Mayo Foundation For Medical Education And Research Methods and vaccines for inducing immune responses to multiple different MHC molecules
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7815920B2 (en) 1998-09-21 2010-10-19 Allergy Therapeutics (UK) Ltd Method of preparing an antigen-containing formulation

Also Published As

Publication number Publication date
US7547681B2 (en) 2009-06-16
CA2351729A1 (en) 2000-05-25
US20030008342A1 (en) 2003-01-09
EP1131432A2 (en) 2001-09-12
US20040219161A1 (en) 2004-11-04
JP2002530294A (en) 2002-09-17
US6734172B2 (en) 2004-05-11
WO2000029582A2 (en) 2000-05-25
WO2000029582A8 (en) 2001-03-01

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