WO2000038782A1 - Regularization of ventricular rate during atrial tachyarrhythmia - Google Patents
Regularization of ventricular rate during atrial tachyarrhythmia Download PDFInfo
- Publication number
- WO2000038782A1 WO2000038782A1 PCT/US1999/030915 US9930915W WO0038782A1 WO 2000038782 A1 WO2000038782 A1 WO 2000038782A1 US 9930915 W US9930915 W US 9930915W WO 0038782 A1 WO0038782 A1 WO 0038782A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ventricular
- pacing
- rate
- atrial
- regularization
- Prior art date
Links
- 230000002861 ventricular Effects 0.000 title claims abstract description 203
- 230000001746 atrial effect Effects 0.000 title claims abstract description 62
- 208000001871 Tachycardia Diseases 0.000 title claims abstract description 16
- 206010049447 Tachyarrhythmia Diseases 0.000 title claims abstract description 12
- 238000001514 detection method Methods 0.000 claims abstract description 9
- 230000000747 cardiac effect Effects 0.000 claims description 19
- 230000034225 regulation of ventricular cardiomyocyte membrane depolarization Effects 0.000 claims description 18
- 230000001965 increasing effect Effects 0.000 claims description 6
- 230000004213 regulation of atrial cardiomyocyte membrane depolarization Effects 0.000 claims description 6
- 230000033764 rhythmic process Effects 0.000 claims description 6
- 230000000717 retained effect Effects 0.000 claims description 4
- 206010042600 Supraventricular arrhythmias Diseases 0.000 claims description 3
- 210000002837 heart atrium Anatomy 0.000 claims description 3
- 230000000977 initiatory effect Effects 0.000 claims 1
- 206010003658 Atrial Fibrillation Diseases 0.000 abstract description 31
- 230000009271 DNA damage immune response Effects 0.000 abstract description 21
- 230000001360 synchronised effect Effects 0.000 abstract description 18
- 101000666382 Homo sapiens Transcription factor E2-alpha Proteins 0.000 abstract description 14
- 102100038313 Transcription factor E2-alpha Human genes 0.000 abstract description 14
- 230000004044 response Effects 0.000 abstract description 12
- 206010003130 Arrhythmia supraventricular Diseases 0.000 abstract description 2
- 230000001684 chronic effect Effects 0.000 abstract description 2
- 230000001314 paroxysmal effect Effects 0.000 abstract 1
- 230000009977 dual effect Effects 0.000 description 11
- 230000000694 effects Effects 0.000 description 11
- 230000007423 decrease Effects 0.000 description 5
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- 238000000034 method Methods 0.000 description 5
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- 238000010586 diagram Methods 0.000 description 4
- 230000028161 membrane depolarization Effects 0.000 description 4
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- 230000002829 reductive effect Effects 0.000 description 3
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- 230000035945 sensitivity Effects 0.000 description 3
- 208000030402 vitamin D-dependent rickets Diseases 0.000 description 3
- 206010003662 Atrial flutter Diseases 0.000 description 2
- 206010065342 Supraventricular tachyarrhythmia Diseases 0.000 description 2
- 206010047281 Ventricular arrhythmia Diseases 0.000 description 2
- 210000001992 atrioventricular node Anatomy 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 239000004020 conductor Substances 0.000 description 2
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- 239000013078 crystal Substances 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 210000005241 right ventricle Anatomy 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 206010049418 Sudden Cardiac Death Diseases 0.000 description 1
- 208000003734 Supraventricular Tachycardia Diseases 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- IYIKLHRQXLHMJQ-UHFFFAOYSA-N amiodarone Chemical compound CCCCC=1OC2=CC=CC=C2C=1C(=O)C1=CC(I)=C(OCCN(CC)CC)C(I)=C1 IYIKLHRQXLHMJQ-UHFFFAOYSA-N 0.000 description 1
- 229960005260 amiodarone Drugs 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 208000006218 bradycardia Diseases 0.000 description 1
- 230000036471 bradycardia Effects 0.000 description 1
- 210000004375 bundle of his Anatomy 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
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- 238000002513 implantation Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 210000005240 left ventricle Anatomy 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
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- 230000009894 physiological stress Effects 0.000 description 1
- 230000001536 pro-arrhythmogenic effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000013577 regulation of ventricular cardiomyocyte membrane repolarization Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000024977 response to activity Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 206010047302 ventricular tachycardia Diseases 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
- A61N1/3622—Heart stimulators for treating or preventing abnormally high heart rate comprising two or more electrodes co-operating with different heart regions
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69919396T DE69919396T2 (en) | 1998-12-28 | 1999-12-22 | REGULATION OF THE VENTRICULAR HEART RATE DURING ATRIAL TACHYARRHYTHMIA |
EP99967630A EP1140287B1 (en) | 1998-12-28 | 1999-12-22 | Regularization of ventricular rate during atrial tachyarrhythmia |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11398898P | 1998-12-28 | 1998-12-28 | |
US60/113,988 | 1998-12-28 | ||
US09/470,120 | 1999-12-22 | ||
US09/470,120 US6434424B1 (en) | 1998-12-28 | 1999-12-22 | Regularization of ventricular rate during atrial tachyarrhythmia |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000038782A1 true WO2000038782A1 (en) | 2000-07-06 |
WO2000038782A9 WO2000038782A9 (en) | 2002-04-11 |
Family
ID=26811719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/030915 WO2000038782A1 (en) | 1998-12-28 | 1999-12-22 | Regularization of ventricular rate during atrial tachyarrhythmia |
Country Status (2)
Country | Link |
---|---|
US (1) | US6434424B1 (en) |
WO (1) | WO2000038782A1 (en) |
Cited By (11)
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WO2002051496A3 (en) * | 2000-12-26 | 2003-01-09 | Cardiac Pacemakers Inc | Apparatus and method for pacing mode switching during atrial tachyarrhythmias |
US6678547B2 (en) | 2001-03-08 | 2004-01-13 | Cardiac Pacemakers, Inc. | Cardiac rhythm management system using time-domain heart rate variability indicia |
US6748272B2 (en) | 2001-03-08 | 2004-06-08 | Cardiac Pacemakers, Inc. | Atrial interval based heart rate variability diagnostic for cardiac rhythm management system |
US7062314B2 (en) | 1999-10-01 | 2006-06-13 | Cardiac Pacemakers, Inc. | Cardiac rhythm management device with triggered diagnostic mode |
US7349734B2 (en) | 2000-05-15 | 2008-03-25 | Cardiac Pacemakers, Inc. | Method and apparatus for delivering defibrillation shock therapy while reducing electrical dispersion due to ventricular conduction disorder |
US7580745B2 (en) | 2005-01-18 | 2009-08-25 | Cardiac Pacemakers, Inc. | Method and apparatus for using heart rate variability to control maximum tracking rate in pacing therapy |
US7672725B2 (en) | 2005-01-18 | 2010-03-02 | Cardiac Pacemakers, Inc. | Method and apparatus for using heart rate variability as a safety check in electrical therapies |
US7672724B2 (en) | 2005-01-18 | 2010-03-02 | Cardiac Pacemakers, Inc. | Method and apparatus for optimizing electrical stimulation parameters using heart rate variability |
WO2010028295A3 (en) * | 2008-09-04 | 2010-10-28 | Medtronic, Inc. | Overlapping pacing and tachyarrhythmia detection zones |
US8886308B2 (en) | 2007-12-11 | 2014-11-11 | Cardiac Pacemakers, Inc. | AV delay features |
US10350419B2 (en) | 2007-12-13 | 2019-07-16 | Cardiac Pacemakers, Inc. | Supraventricular tachy sensing vector |
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US7212860B2 (en) * | 1999-05-21 | 2007-05-01 | Cardiac Pacemakers, Inc. | Apparatus and method for pacing mode switching during atrial tachyarrhythmias |
US7181278B2 (en) * | 1999-05-21 | 2007-02-20 | Cardiac Pacemakers, Inc. | Apparatus and method for ventricular rate regularization |
US8064997B2 (en) | 1999-05-21 | 2011-11-22 | Cardiac Pacemakers, Inc. | Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia |
US6519493B1 (en) * | 1999-12-23 | 2003-02-11 | Pacesetter, Inc. | Methods and apparatus for overdrive pacing heart tissue using an implantable cardiac stimulation device |
US7039461B1 (en) | 2000-05-13 | 2006-05-02 | Cardiac Pacemakers, Inc. | Cardiac pacing system for prevention of ventricular fibrillation and ventricular tachycardia episode |
US8512220B2 (en) | 2000-05-26 | 2013-08-20 | Cardiac Pacemakers, Inc. | Rate smoothing control |
US7738955B2 (en) * | 2000-12-21 | 2010-06-15 | Medtronic, Inc. | System and method for ventricular pacing with AV interval modulation |
US7245966B2 (en) | 2000-12-21 | 2007-07-17 | Medtronic, Inc. | Ventricular event filtering for an implantable medical device |
US9931509B2 (en) | 2000-12-21 | 2018-04-03 | Medtronic, Inc. | Fully inhibited dual chamber pacing mode |
US6957100B2 (en) | 2000-12-26 | 2005-10-18 | Cardiac Pacemakers, Inc. | Method and system for display of cardiac event intervals in a resynchronization pacemaker |
US20020087198A1 (en) * | 2000-12-29 | 2002-07-04 | Kramer Andrew P. | Apparatus and method for ventricular rate regularization |
US6907295B2 (en) | 2001-08-31 | 2005-06-14 | Biocontrol Medical Ltd. | Electrode assembly for nerve control |
US7974693B2 (en) * | 2001-08-31 | 2011-07-05 | Bio Control Medical (B.C.M.) Ltd. | Techniques for applying, configuring, and coordinating nerve fiber stimulation |
US7904176B2 (en) | 2006-09-07 | 2011-03-08 | Bio Control Medical (B.C.M.) Ltd. | Techniques for reducing pain associated with nerve stimulation |
US7885709B2 (en) | 2001-08-31 | 2011-02-08 | Bio Control Medical (B.C.M.) Ltd. | Nerve stimulation for treating disorders |
US7778711B2 (en) | 2001-08-31 | 2010-08-17 | Bio Control Medical (B.C.M.) Ltd. | Reduction of heart rate variability by parasympathetic stimulation |
US8571653B2 (en) | 2001-08-31 | 2013-10-29 | Bio Control Medical (B.C.M.) Ltd. | Nerve stimulation techniques |
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US7885711B2 (en) | 2003-06-13 | 2011-02-08 | Bio Control Medical (B.C.M.) Ltd. | Vagal stimulation for anti-embolic therapy |
US7844346B2 (en) | 2002-05-23 | 2010-11-30 | Biocontrol Medical Ltd. | Electrode assembly for nerve control |
US8204591B2 (en) | 2002-05-23 | 2012-06-19 | Bio Control Medical (B.C.M.) Ltd. | Techniques for prevention of atrial fibrillation |
US7844332B2 (en) | 2002-10-18 | 2010-11-30 | Cardiac Pacemakers, Inc. | Atrioventricular delay adjustment enhancing ventricular tachyarrhythmia detection |
US8880192B2 (en) | 2012-04-02 | 2014-11-04 | Bio Control Medical (B.C.M.) Ltd. | Electrode cuffs |
US7627384B2 (en) | 2004-11-15 | 2009-12-01 | Bio Control Medical (B.C.M.) Ltd. | Techniques for nerve stimulation |
US8060197B2 (en) * | 2003-05-23 | 2011-11-15 | Bio Control Medical (B.C.M.) Ltd. | Parasympathetic stimulation for termination of non-sinus atrial tachycardia |
US7158829B1 (en) | 2003-12-05 | 2007-01-02 | Pacesetter, Inc. | Method and apparatus for improving specificity of atrial tachycardia detection techniques in dual-unipolar or dual-bipolar implantable cardiac stimulation systems |
US7184834B1 (en) | 2003-12-05 | 2007-02-27 | Pacesetter, Inc. | Method and apparatus for improving specificity of atrial tachycardia detection techniques in dual-unipolar or dual-bipolar implantable cardiac stimulation systems |
US7146213B1 (en) * | 2003-12-05 | 2006-12-05 | Pacesetter, Inc. | Method and apparatus for improving specificity of atrial tachycardia detection techniques in dual-unipolar or dual-bipolar implantable cardiac stimulation systems |
US7174210B1 (en) | 2003-12-05 | 2007-02-06 | Pacesetter, Inc. | Method and apparatus for improving specificity of atrial tachycardia detection techniques in dual-unipolar or dual-bipolar implantable cardiac stimulation systems |
US7532929B2 (en) | 2004-02-23 | 2009-05-12 | Biotronik Crm Patent Ag | Adaptive ventricular rate smoothing during atrial fibrillation |
CA2998199A1 (en) | 2004-06-01 | 2005-12-15 | Kwalata Trading Limited | Methods for use with stem cells involving culturing on a surface with antibodies |
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US7542799B2 (en) * | 2005-01-21 | 2009-06-02 | Medtronic, Inc. | Implantable medical device with ventricular pacing protocol |
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US9510764B2 (en) | 2009-04-22 | 2016-12-06 | Cardiac Pacemakers, Inc. | Methods for detecting atrial tachyarrhythmia in implantable devices without dedicated atrial sensing |
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US11617889B2 (en) | 2018-04-20 | 2023-04-04 | Medtronic, Inc. | Rate smoothing to enhance atrial synchronous pacing in a ventricular pacemaker |
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1999
- 1999-12-22 US US09/470,120 patent/US6434424B1/en not_active Expired - Lifetime
- 1999-12-22 WO PCT/US1999/030915 patent/WO2000038782A1/en active IP Right Grant
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