WO2000039587A1 - Composite arrays utilizing microspheres - Google Patents
Composite arrays utilizing microspheres Download PDFInfo
- Publication number
- WO2000039587A1 WO2000039587A1 PCT/US1999/031022 US9931022W WO0039587A1 WO 2000039587 A1 WO2000039587 A1 WO 2000039587A1 US 9931022 W US9931022 W US 9931022W WO 0039587 A1 WO0039587 A1 WO 0039587A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- array
- beads
- microspheres
- decoding
- substrate
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00382—Stamping
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
- B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
Abstract
Description
Claims
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000591435A JP3566653B2 (en) | 1998-12-28 | 1999-12-28 | Composite array using microspheres |
EP99967670.3A EP1141712B2 (en) | 1998-12-28 | 1999-12-28 | Composite arrays utilizing microspheres |
DE29925020U DE29925020U1 (en) | 1998-12-28 | 1999-12-28 | Composite arrays with microspheres |
AU23916/00A AU775056B2 (en) | 1998-12-28 | 1999-12-28 | Composite arrays utilizing microspheres |
DE69926260.7T DE69926260T3 (en) | 1998-12-28 | 1999-12-28 | COMPOSITE MATRIX WITH MICROBALLS |
AT99967670T ATE300047T1 (en) | 1998-12-28 | 1999-12-28 | COMPOSITE MATRIX WITH MICRO BALLS |
CA2353868A CA2353868C (en) | 1998-12-28 | 1999-12-28 | Composite arrays utilizing microspheres |
US12/405,170 US20090227472A1 (en) | 1998-12-28 | 2009-03-16 | Array systems and components |
US12/405,162 US8628952B2 (en) | 1998-12-28 | 2009-03-16 | Array kits and processing systems |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11396898P | 1998-12-28 | 1998-12-28 | |
US60/113,968 | 1998-12-28 | ||
US09/256,943 US6429027B1 (en) | 1998-12-28 | 1999-02-24 | Composite arrays utilizing microspheres |
US09/256,943 | 1999-02-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2000039587A1 true WO2000039587A1 (en) | 2000-07-06 |
Family
ID=26811698
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/031022 WO2000039587A1 (en) | 1998-12-28 | 1999-12-28 | Composite arrays utilizing microspheres |
Country Status (8)
Country | Link |
---|---|
US (3) | US6429027B1 (en) |
EP (3) | EP1141712B2 (en) |
JP (2) | JP3566653B2 (en) |
AT (2) | ATE300047T1 (en) |
AU (1) | AU775056B2 (en) |
CA (2) | CA2729739C (en) |
DE (3) | DE69941068D1 (en) |
WO (1) | WO2000039587A1 (en) |
Cited By (126)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2000060332A2 (en) * | 1999-04-06 | 2000-10-12 | Trustees Of Tufts College | Self-encoding sensor with microspheres |
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WO2002028530A2 (en) * | 2000-10-06 | 2002-04-11 | Trustees Of Tufts College | Self-encoding sensor arrays with microspheres |
WO2001059432A3 (en) * | 2000-02-10 | 2002-04-18 | Illumina Inc | Array of individual arrays as substrate for bead-based simultaneous processing of samples and manufacturing method therefor |
WO2002042775A2 (en) * | 2000-11-27 | 2002-05-30 | Genevention L.L.C. | Clinically intelligent diagnostic devices and methods |
WO2002084283A2 (en) * | 2001-04-10 | 2002-10-24 | Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Universität Tübingen In Reutlingen Stiftung Bürgerlichen Rechts | Method for determining analyte molecules in a sample |
WO2002090945A2 (en) * | 2001-05-03 | 2002-11-14 | Technische Universiteit Delft | Method of performing an assay, apparatus therefor, and a method of manufacturing and apparatus |
WO2002096552A2 (en) * | 2001-06-01 | 2002-12-05 | Scientific Generics Limited | Biochip and apparatus and methods for its manufacture and use |
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DE69926260T3 (en) | 2016-05-19 |
EP1593967B1 (en) | 2009-07-01 |
EP1593967A2 (en) | 2005-11-09 |
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CA2729739C (en) | 2013-01-29 |
ATE300047T1 (en) | 2005-08-15 |
DE69941068D1 (en) | 2009-08-13 |
EP1141712B1 (en) | 2005-07-20 |
DE69926260D1 (en) | 2005-08-25 |
CA2353868C (en) | 2011-03-29 |
US6858394B1 (en) | 2005-02-22 |
ATE435423T1 (en) | 2009-07-15 |
JP2004226415A (en) | 2004-08-12 |
DE69926260T2 (en) | 2006-04-27 |
US6429027B1 (en) | 2002-08-06 |
AU2391600A (en) | 2000-07-31 |
US20020187515A1 (en) | 2002-12-12 |
EP2083271A3 (en) | 2009-09-09 |
AU775056B2 (en) | 2004-07-15 |
EP1141712A1 (en) | 2001-10-10 |
CA2353868A1 (en) | 2000-07-06 |
DE29925020U1 (en) | 2009-09-10 |
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US6998274B2 (en) | 2006-02-14 |
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