WO2000054650A3 - Apparatus and method for non-invasive, passive fetal heart monitoring - Google Patents

Apparatus and method for non-invasive, passive fetal heart monitoring Download PDF

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Publication number
WO2000054650A3
WO2000054650A3 PCT/US2000/006295 US0006295W WO0054650A3 WO 2000054650 A3 WO2000054650 A3 WO 2000054650A3 US 0006295 W US0006295 W US 0006295W WO 0054650 A3 WO0054650 A3 WO 0054650A3
Authority
WO
WIPO (PCT)
Prior art keywords
fetal
abdominal
mother
sensors
wave forms
Prior art date
Application number
PCT/US2000/006295
Other languages
French (fr)
Other versions
WO2000054650A2 (en
Inventor
Robert S Greenberg
John A Cristion
Edward J Moses
Wayne I Sternberger
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Priority to AU37367/00A priority Critical patent/AU758778B2/en
Priority to CA002345720A priority patent/CA2345720C/en
Priority to JP2000604738A priority patent/JP2002538872A/en
Priority to EP00916231A priority patent/EP1168961A4/en
Publication of WO2000054650A2 publication Critical patent/WO2000054650A2/en
Publication of WO2000054650A3 publication Critical patent/WO2000054650A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/30—Input circuits therefor
    • A61B5/307—Input circuits therefor specially adapted for particular uses
    • A61B5/308—Input circuits therefor specially adapted for particular uses for electrocardiography [ECG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02405—Determining heart rate variability
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/30—Input circuits therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/344—Foetal cardiography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4343—Pregnancy and labour monitoring, e.g. for labour onset detection
    • A61B5/4362—Assessing foetal parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02411—Detecting, measuring or recording pulse rate or heart rate of foetuses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
    • A61B5/282—Holders for multiple electrodes

Abstract

An apparatus, a method for fetal heart, maternal heart, and uterine monitoring is provided which acquire bio-potential wave forms indicative of the mother's heart beat from sensors (10) located at or near the mother's chest; wave forms indicative of the combined maternal, and fetal heartbeats from the abdominal sensors located on the mother's abdomen, lower back, or both. The signals from the abdominal sensors are divided into a plurality of channels. An adaptive signal processing filter (ASPF) algorithm or suitable algorithm is then used to cancel the estimated maternal waveform from each channel derived from the abdominal sensors. The system than selects from the resulting wave forms at least one wave form to serve as the reference fetal wave form. The reference wave form is then processed against the other abdominal wave forms preferably using the ASPF algorithm again to form an enhance the fetal signal that is a representation of the fetus's bio-potential electrocardiogram (EKG). The EKG can subsequently be used to measure fetal heart rate, and other biophysical profile parameters. Surface electromyogram (EMG) signals allow for concurrent monitoring of uterine contractions, and afford improved cancellation of motion artifacts.
PCT/US2000/006295 1999-03-15 2000-03-10 Apparatus and method for non-invasive, passive fetal heart monitoring WO2000054650A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU37367/00A AU758778B2 (en) 1999-03-15 2000-03-10 Apparatus and method for non-invasive, passive fetal heart monitoring
CA002345720A CA2345720C (en) 1999-03-15 2000-03-10 Apparatus and method for non-invasive, passive fetal heart monitoring
JP2000604738A JP2002538872A (en) 1999-03-15 2000-03-10 Apparatus and method for non-invasively and passively monitoring a fetal heart
EP00916231A EP1168961A4 (en) 1999-03-15 2000-03-10 Apparatus and method for non-invasive, passive fetal heart monitoring

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12444799P 1999-03-15 1999-03-15
US60/124,447 1999-03-15

Publications (2)

Publication Number Publication Date
WO2000054650A2 WO2000054650A2 (en) 2000-09-21
WO2000054650A3 true WO2000054650A3 (en) 2001-02-15

Family

ID=22414929

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/006295 WO2000054650A2 (en) 1999-03-15 2000-03-10 Apparatus and method for non-invasive, passive fetal heart monitoring

Country Status (5)

Country Link
EP (1) EP1168961A4 (en)
JP (1) JP2002538872A (en)
AU (1) AU758778B2 (en)
CA (1) CA2345720C (en)
WO (1) WO2000054650A2 (en)

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GB0123772D0 (en) * 2001-10-03 2001-11-21 Qinetiq Ltd Apparatus for monitoring fetal heartbeat
GB0130906D0 (en) 2001-12-22 2002-02-13 Jopejo Ltd Heart monitor
GB0306629D0 (en) 2003-03-22 2003-04-30 Qinetiq Ltd Monitoring electrical muscular activity
CA2538710A1 (en) * 2003-09-12 2005-03-31 Bodymedia, Inc. Method and apparatus for measuring heart related parameters
ATE483398T1 (en) 2003-10-14 2010-10-15 Monica Healthcare Ltd FETUS MONITORING
US7333850B2 (en) 2004-05-28 2008-02-19 University Of Florida Research Foundation, Inc. Maternal-fetal monitoring system
JP4590554B2 (en) * 2005-01-31 2010-12-01 国立大学法人東北大学 ECG signal processing method and ECG signal processing apparatus
WO2007029485A1 (en) 2005-09-05 2007-03-15 Tohoku University Non-linear signal separation method using non-linear state space projection method
WO2008090862A1 (en) 2007-01-23 2008-07-31 Tohoku Techno Arch Co., Ltd. Fetus electrocardiogram signal measuring method and its device
EP2185068B1 (en) 2007-07-20 2016-09-07 Stichting voor de Technische Wetenschappen Fetal monitoring
EP2276401A4 (en) * 2008-04-15 2014-02-05 Tufts Medical Ct Fetal ecg monitoring
US9002427B2 (en) 2009-03-30 2015-04-07 Lifewave Biomedical, Inc. Apparatus and method for continuous noninvasive measurement of respiratory function and events
US20100274145A1 (en) 2009-04-22 2010-10-28 Tupin Jr Joe Paul Fetal monitoring device and methods
NZ597459A (en) 2009-07-06 2014-01-31 Heard Systems Pty Ltd Non-invasively measuring physiological process
US8702604B2 (en) 2011-01-31 2014-04-22 Medtronic, Inc. Detection of waveform artifact
CN103006199B (en) 2011-09-26 2016-09-28 三星电子株式会社 For measuring equipment and the method for bio signal
KR101941171B1 (en) * 2011-09-26 2019-01-23 삼성전자주식회사 Apparatus and method for measuring biological signal
US8892181B2 (en) * 2011-10-21 2014-11-18 Mindchild Medical, Inc. Non-invasive fetal monitoring
KR101554381B1 (en) * 2012-07-30 2015-09-18 가톨릭대학교 산학협력단 Method and apparatus for performing fetal health
WO2014086260A1 (en) * 2012-12-07 2014-06-12 河南华南医电科技有限公司 Fetal electrocardiogram device based on orthogonal lead
WO2015145624A1 (en) 2014-03-26 2015-10-01 国立大学法人東北大学 Fetal state estimation device, fetal state estimation method, and fetal state estimation program
CN105249952A (en) * 2015-11-18 2016-01-20 苏州思源通科技有限公司 Gravida and fetus detector device based on blind signal processing
CN107049303A (en) * 2017-03-10 2017-08-18 哈尔滨工业大学 It is a kind of that the adaptive Fetal ECG signal extraction system and method led with many chests is led based on many abdomens
KR102099501B1 (en) * 2017-11-28 2020-04-09 전자부품연구원 Device for monitoring preterm birth risk, and Method and recording medium applying the same
JP2020138022A (en) * 2019-02-27 2020-09-03 国立大学法人信州大学 Fetal heart rate measurement method and simultaneous monitoring method for fetus and its mother
EP4027871A4 (en) * 2019-09-11 2023-08-30 Northwestern University Multiplexed wearable sensors for pregnancy monitoring and applications of same
CN110604564B (en) * 2019-09-16 2023-01-17 深圳市理邦精密仪器股份有限公司 Electrode system, fetal electrocardiosignal acquisition and measurement method and device
AU2021288685A1 (en) * 2020-06-09 2023-02-02 Cardiac Motion, LLC Maternal and fetal heart rate monitor

Citations (2)

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Publication number Priority date Publication date Assignee Title
US4519396A (en) * 1979-03-30 1985-05-28 American Home Products Corporation (Del.) Fetal heart rate monitor apparatus and method for combining electrically and mechanically derived cardiographic signals
US5833622A (en) * 1994-04-04 1998-11-10 Graphic Controls Corporation Non-invasive fetal probe having improved mechanical and electrical properties

Family Cites Families (2)

* Cited by examiner, † Cited by third party
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IL82698A0 (en) * 1987-05-29 1987-11-30 Univ Ramot Method and apparatus for indicating repetition intervals of a specified component of a composite electrical signal,particularly useful for displaying fetal r-waves
US5372139A (en) * 1991-06-24 1994-12-13 Paul Benjamin Crilly Method for suppressing a maternal electrocardiogram signal from a fetal electrocardiogram signal obtained with invasive and non-invasive techniques using an almost pure maternal electrocardiogram signal as a trigger

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4519396A (en) * 1979-03-30 1985-05-28 American Home Products Corporation (Del.) Fetal heart rate monitor apparatus and method for combining electrically and mechanically derived cardiographic signals
US5833622A (en) * 1994-04-04 1998-11-10 Graphic Controls Corporation Non-invasive fetal probe having improved mechanical and electrical properties

Also Published As

Publication number Publication date
CA2345720C (en) 2005-01-04
JP2002538872A (en) 2002-11-19
EP1168961A2 (en) 2002-01-09
EP1168961A4 (en) 2003-05-02
AU758778B2 (en) 2003-03-27
CA2345720A1 (en) 2000-09-21
AU3736700A (en) 2000-10-04
WO2000054650A2 (en) 2000-09-21

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