WO2000059571A3 - Brachytherapy device and method - Google Patents

Brachytherapy device and method Download PDF

Info

Publication number
WO2000059571A3
WO2000059571A3 PCT/US2000/009076 US0009076W WO0059571A3 WO 2000059571 A3 WO2000059571 A3 WO 2000059571A3 US 0009076 W US0009076 W US 0009076W WO 0059571 A3 WO0059571 A3 WO 0059571A3
Authority
WO
WIPO (PCT)
Prior art keywords
radioactive
capsule
seed
brachytherapy device
bombardement
Prior art date
Application number
PCT/US2000/009076
Other languages
French (fr)
Other versions
WO2000059571A2 (en
Inventor
Malcolm D Heaven
Original Assignee
Imagyn Medical Technologies In
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imagyn Medical Technologies In filed Critical Imagyn Medical Technologies In
Priority to AU47979/00A priority Critical patent/AU4797900A/en
Publication of WO2000059571A2 publication Critical patent/WO2000059571A2/en
Publication of WO2000059571A3 publication Critical patent/WO2000059571A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1027—Interstitial radiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N2005/1019—Sources therefor
    • A61N2005/1024—Seeds

Abstract

This invention relates to the manufacture of small radioactive seeds used for implantation into tumors to eradicate cancerous cells, and used as an alternative to external radiation therapy such as electron beam irradiation. The seed is produced by inserting at least one image marker (20) and introducing X-124 into the capsule (12). The conversion of non-radioactive Xe-124 to radioactive I-125 occurs in the sealed capsule (12) after welding capsule end (18) and irradiating in a nuclear reactor. The activity of the seed is controlled by varying the pressure and/or the amount of neutron bombardement.
PCT/US2000/009076 1999-04-06 2000-04-05 Brachytherapy device and method WO2000059571A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU47979/00A AU4797900A (en) 1999-04-06 2000-04-05 Brachytherapy device and method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12803899P 1999-04-06 1999-04-06
US60/128,038 1999-04-06

Publications (2)

Publication Number Publication Date
WO2000059571A2 WO2000059571A2 (en) 2000-10-12
WO2000059571A3 true WO2000059571A3 (en) 2001-05-10

Family

ID=22433304

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/009076 WO2000059571A2 (en) 1999-04-06 2000-04-05 Brachytherapy device and method

Country Status (2)

Country Link
AU (1) AU4797900A (en)
WO (1) WO2000059571A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503186B1 (en) 1997-08-01 2003-01-07 North American Scientific, Inc. Radioactive seed with multiple markers and method for using same
US6800055B2 (en) 2001-02-21 2004-10-05 Cordis Corporation Low attenuating radioactive seeds
DE102005016956A1 (en) * 2005-04-12 2006-10-19 Nttf Gmbh Activatable implant, in particular Seed
DE202006009375U1 (en) * 2006-06-14 2007-10-18 Reinmüller, Johannes, Dr.med. Implantable device
US20090216063A1 (en) * 2008-01-29 2009-08-27 Biocompatibles Uk Limited Bio-absorbable brachytherapy strands

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3351049A (en) * 1965-04-12 1967-11-07 Hazleton Nuclear Science Corp Therapeutic metal seed containing within a radioactive isotope disposed on a carrier and method of manufacture
US4323055A (en) * 1980-04-08 1982-04-06 Minnesota Mining And Manufacturing Company Radioactive iodine seed
US4729903A (en) * 1986-06-10 1988-03-08 Midi-Physics, Inc. Process for depositing I-125 onto a substrate used to manufacture I-125 sources
US4784116A (en) * 1985-01-24 1988-11-15 Theragenics Corporation Capsule for interstitial implants
US5633900A (en) * 1993-10-04 1997-05-27 Hassal; Scott B. Method and apparatus for production of radioactive iodine
US5997463A (en) * 1998-03-26 1999-12-07 North American Scientific Laser welded brachytherapy source and method of making the same
US6010445A (en) * 1997-09-11 2000-01-04 Implant Sciences Corporation Radioactive medical device and process

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3351049A (en) * 1965-04-12 1967-11-07 Hazleton Nuclear Science Corp Therapeutic metal seed containing within a radioactive isotope disposed on a carrier and method of manufacture
US4323055A (en) * 1980-04-08 1982-04-06 Minnesota Mining And Manufacturing Company Radioactive iodine seed
US4784116A (en) * 1985-01-24 1988-11-15 Theragenics Corporation Capsule for interstitial implants
US4729903A (en) * 1986-06-10 1988-03-08 Midi-Physics, Inc. Process for depositing I-125 onto a substrate used to manufacture I-125 sources
US5633900A (en) * 1993-10-04 1997-05-27 Hassal; Scott B. Method and apparatus for production of radioactive iodine
US6010445A (en) * 1997-09-11 2000-01-04 Implant Sciences Corporation Radioactive medical device and process
US5997463A (en) * 1998-03-26 1999-12-07 North American Scientific Laser welded brachytherapy source and method of making the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MARTINHO E. ET AL.: "I-125 Production: Neutron irradiation planning", INT. J. APPL. RADIAT. ISOT., vol. 35, no. 10, 1984, pages 933 - 938, XP002937916 *

Also Published As

Publication number Publication date
WO2000059571A2 (en) 2000-10-12
AU4797900A (en) 2000-10-23

Similar Documents

Publication Publication Date Title
Ongaro et al. Analysis of photoneutron spectra produced in medical accelerators
EP0210269B1 (en) X-ray-emitting interstitial implants
CA2291270C (en) Combination radioactive and temperature self-regulating thermal seed implant for treating tumors
US5575749A (en) Ultra-thin high dose radioactive source wire
US6419621B1 (en) Coiled brachytherapy device
US5395300A (en) High dosage radioactive source
Ling et al. Physical dosimetry of 125I seeds of a new design for interstitial implant
EP1463533B1 (en) Radioactive ion
US6007475A (en) Radioactive therapeutic seeds
Richter et al. Comparison of 60cobalt and 192iridium sources in high dose rate afterloading brachytherapy
Henschke et al. Cesium-131 seeds for permanent implants
EP1218061A2 (en) Neutron brachytherapy device and method
WO2000059571A3 (en) Brachytherapy device and method
Rostelato et al. Development and production of radioactive sources used for cancer treatment in Brazil
EP3668596A2 (en) Surgically positioned neutron flux activated high energy therapeutic charged particle generation system
RU2343935C2 (en) Methods of manufacturing of implants for brachytherapy
Nath New directions in radionuclide sources for brachytherapy
Meli et al. The effect of lead, gold, and silver backings on dose near 125I seeds
Coursey et al. The needs for brachytherapy source calibrations in the United States
US20030120128A1 (en) Low-energy brachytherapy sources
Meigooni et al. Design and dosimetric characteristics of a high dose rate remotely afterloaded endocavitary applicator system
WO2023107039A2 (en) Pr-142 medium dose rate/high dose rate brachytherapy radioisotope source production method in line- and disc- source form
Dale et al. Applications of thermal neutron generators driven with a repetitively pulsed electron linac
JP2024508814A (en) Apparatus, system, and method for irradiating delta rays using prompt neutron capture gamma rays
EP1946797A2 (en) Radioactive ion

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ CZ DE DE DK DK DM DZ EE EE ES FI FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ CZ DE DE DK DK DM DZ EE EE ES FI FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP