WO2000062763A3 - Carrier patch for the delivery of agents to the skin - Google Patents

Carrier patch for the delivery of agents to the skin Download PDF

Info

Publication number
WO2000062763A3
WO2000062763A3 PCT/US2000/010108 US0010108W WO0062763A3 WO 2000062763 A3 WO2000062763 A3 WO 2000062763A3 US 0010108 W US0010108 W US 0010108W WO 0062763 A3 WO0062763 A3 WO 0062763A3
Authority
WO
WIPO (PCT)
Prior art keywords
patch
skin
delivery
agents
agent
Prior art date
Application number
PCT/US2000/010108
Other languages
French (fr)
Other versions
WO2000062763A2 (en
Inventor
Jerome D Muchin
Original Assignee
Acutek Internat
Jerome D Muchin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acutek Internat, Jerome D Muchin filed Critical Acutek Internat
Priority to AU44609/00A priority Critical patent/AU4460900A/en
Publication of WO2000062763A2 publication Critical patent/WO2000062763A2/en
Publication of WO2000062763A3 publication Critical patent/WO2000062763A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive plasters or dressings
    • A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F2013/0296—Apparatus or processes for manufacturing adhesive dressings or bandages for making transdermal patches (chemical processes excluded)

Abstract

A carrier patch for delivering agents locally to the skin or systemically via the skin. The patch comprises a pad having a lower surface area to which an adhesive is adhered, and a primary agent applied to discrete regions of the patch in a manner to minimize the deleterious effects of the adhesive on the primary agent. The invention further comprises a method for the discrete application of the agent to the patch, and a method of using the patch for the delivery of the agent to the skin.
PCT/US2000/010108 1999-04-15 2000-04-14 Carrier patch for the delivery of agents to the skin WO2000062763A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU44609/00A AU4460900A (en) 1999-04-15 2000-04-14 Carrier patch for the delivery of agents to the skin

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/292,625 1999-04-15
US09/292,625 US6183770B1 (en) 1999-04-15 1999-04-15 Carrier patch for the delivery of agents to the skin

Publications (2)

Publication Number Publication Date
WO2000062763A2 WO2000062763A2 (en) 2000-10-26
WO2000062763A3 true WO2000062763A3 (en) 2001-01-04

Family

ID=23125474

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/010108 WO2000062763A2 (en) 1999-04-15 2000-04-14 Carrier patch for the delivery of agents to the skin

Country Status (3)

Country Link
US (2) US6183770B1 (en)
AU (1) AU4460900A (en)
WO (1) WO2000062763A2 (en)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6769428B2 (en) 1997-01-29 2004-08-03 Peter J. Cronk Adhesively applied external nasal strips and dilators containing medications and fragrances
US6550474B1 (en) * 1997-01-29 2003-04-22 Cns, Inc. Microencapsulated fragrances and methods of coating microcapsules
US20060029653A1 (en) 1997-01-29 2006-02-09 Cronk Peter J Therapeutic delivery system
AUPQ419099A0 (en) * 1999-11-23 1999-12-16 Ko, Thomas Sai Ying Novel compositions and methods
US6821281B2 (en) * 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
FR2821061B1 (en) * 2001-02-22 2003-04-04 Oreal PROCESS FOR PACKAGING A PRODUCT
DE10121471A1 (en) * 2001-05-02 2002-11-07 Beiersdorf Ag Plaster for controlled release of active agent to skin or wounds, comprising adsorbent, pressure-sensitive adhesive matrix surface-doped with active agent, e.g. dexpanthenol
US6893655B2 (en) * 2001-10-09 2005-05-17 3M Innovative Properties Co. Transdermal delivery devices
US7938812B2 (en) * 2001-10-26 2011-05-10 Sca Hygiene Products Ab Insert for an absorbent article with skincare agent and spacing sheet
US6649181B1 (en) * 2002-05-29 2003-11-18 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Cosmetic adhesive strip
US7060867B2 (en) * 2002-11-27 2006-06-13 Kimberly-Clark Worldwide, Inc. Absorbent article with a body facing liner having discretely placed lotion deposits
US7098189B2 (en) * 2002-12-16 2006-08-29 Kimberly-Clark Worldwide, Inc. Wound and skin care compositions
US20040180093A1 (en) * 2003-03-12 2004-09-16 3M Innovative Properties Company Polymer compositions with bioactive agent, medical articles, and methods
EP1606189A2 (en) * 2003-03-26 2005-12-21 Lavipharm S.A. Methods and devices for holding a composition
UA82880C2 (en) * 2003-04-30 2008-05-26 Tamper-resistant transdermal dosage form comprising an active agent component and an adverse agent component at the distal site of the active agent layer
US8790689B2 (en) * 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
US7888546B2 (en) * 2003-07-03 2011-02-15 Corium International, Inc. Wound dressing, ingredient delivery device and IV hold-down, and method relating to same
US7745509B2 (en) * 2003-12-05 2010-06-29 3M Innovative Properties Company Polymer compositions with bioactive agent, medical articles, and methods
US7316817B2 (en) * 2004-01-02 2008-01-08 New Medical Technologies, Inc. Method and device for topical delivery of therapeutic agents to the skin
US20080131493A1 (en) * 2004-01-02 2008-06-05 Haitham Matloub Method and Multilayered Device for Controlled Topical Delivery of Therapeutic Agents to the Skin
US8591940B2 (en) * 2004-01-02 2013-11-26 New Medical Technology Inc. Method of treating scar tissue
US7758939B2 (en) * 2004-01-08 2010-07-20 Marchitto Kevin S Adhesive laminates for rapid wound occlusion
EP1737357B1 (en) * 2004-03-24 2019-12-11 Corium, Inc. Transdermal delivery device
US7452547B2 (en) 2004-03-31 2008-11-18 Johnson&Johnson Consumer Co., Inc. Product for treating the skin comprising a polyamine microcapsule wall and a skin lightening agent
US20060034899A1 (en) * 2004-08-12 2006-02-16 Ylitalo Caroline M Biologically-active adhesive articles and methods of manufacture
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
CA2588295C (en) 2004-11-23 2013-10-22 Neuromolecular Pharmaceuticals, Inc. Method and composition for administering an nmda receptor antagonist to a subject
PL1874282T3 (en) 2005-04-06 2011-04-29 Adamas Pharmaceuticals Inc Methods and compositions for treatment of cns disorders
US8399027B2 (en) * 2005-04-14 2013-03-19 3M Innovative Properties Company Silver coatings and methods of manufacture
US7846445B2 (en) * 2005-09-27 2010-12-07 Amunix Operating, Inc. Methods for production of unstructured recombinant polymers and uses thereof
US7855279B2 (en) * 2005-09-27 2010-12-21 Amunix Operating, Inc. Unstructured recombinant polymers and uses thereof
JP2009509535A (en) * 2005-09-27 2009-03-12 アムニクス， インコーポレイテッド Proteinaceous drugs and their use
US20090099031A1 (en) * 2005-09-27 2009-04-16 Stemmer Willem P Genetic package and uses thereof
US20070166399A1 (en) 2006-01-13 2007-07-19 3M Innovative Properties Company Silver-containing antimicrobial articles and methods of manufacture
CA2662018A1 (en) 2006-08-30 2008-03-06 David William Smith Method of imparting a mono-axial or multiaxial stiffness to extruded materials and products resulting therefrom
US20100098949A1 (en) * 2006-10-18 2010-04-22 Burton Scott A Antimicrobial articles and method of manufacture
EP2121111B1 (en) * 2007-01-22 2018-03-14 Corium International, Inc. Applicators for microneedle arrays
EP2146689B1 (en) 2007-04-16 2020-08-12 Corium, Inc. Solvent-cast microneedle arrays containing active
US8911749B2 (en) * 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
BRPI0815416A2 (en) * 2007-08-15 2014-10-21 Amunix Inc COMPOSITIONS AND METHODS FOR MODIFYING PROPERTIES OF BIOLOGICALLY ACTIVE POLYPEPTIDES
JP5178132B2 (en) * 2007-10-11 2013-04-10 キヤノン株式会社 Image processing system and image processing method
EP3178835B1 (en) 2009-02-03 2019-04-10 Amunix Pharmaceuticals, Inc. Extended recombinant polypeptides and compositions comprising same
EP2429627B1 (en) * 2009-04-24 2017-06-14 Corium International, Inc. Methods for manufacturing microprojection arrays
US20110000483A1 (en) * 2009-05-01 2011-01-06 Matthias Joseph A External nasal dilator
JP5839597B2 (en) 2009-06-08 2016-01-06 アムニクス オペレーティング インコーポレイテッド Glucose-regulating polypeptide and methods for making and using the same
LT2440241T (en) 2009-06-08 2017-10-10 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
EP2470670A4 (en) 2009-08-24 2013-07-10 Amunix Operating Inc Coagulation factor vii compositions and methods of making and using same
US8741343B2 (en) 2009-12-02 2014-06-03 Adamas Pharmaceuticals, Inc. Method of administering amantadine prior to a sleep period
US8952038B2 (en) 2010-03-26 2015-02-10 Philip Morris Usa Inc. Inhibition of undesired sensory effects by the compound camphor
KR101831463B1 (en) 2010-03-26 2018-02-22 필립모리스 프로덕츠 에스.에이. Inhibition of sensory irritation during consumption of non-smokeable tobacco products
EP2566501B1 (en) 2010-05-04 2019-03-13 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
DE102010024105A1 (en) * 2010-06-17 2011-12-22 Grünenthal GmbH Transdermal administration of memantine
PT2804734T (en) 2012-01-20 2016-07-07 Acino Ag Reduced loss of lattice material in patch manufacturing
HUE046848T2 (en) 2012-02-15 2020-03-30 Bioverativ Therapeutics Inc Factor viii compositions and methods of making and using same
EP2822577B1 (en) 2012-02-15 2019-02-06 Bioverativ Therapeutics Inc. Recombinant factor viii proteins
EP2934660B1 (en) 2012-12-21 2019-07-17 Corium, Inc. Microarray for delivery of therapeutic agent and method of making same
EP2968887B1 (en) 2013-03-12 2022-05-04 Corium, Inc. Microprojection applicators
JP2016514133A (en) 2013-03-15 2016-05-19 コリウム インターナショナル， インコーポレイテッド MICROARRAY CONTAINING FINE STRUCTURE CONTAINING NO POLYMER, MANUFACTURING METHOD AND USE METHOD
ES2939317T3 (en) 2013-03-15 2023-04-20 Corium Pharma Solutions Inc Multi-impact micro-spray applicators
BR112015022625B1 (en) 2013-03-15 2023-01-31 Corium, Inc MICROSTRUCTURE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT
ES2761580T3 (en) 2013-03-15 2020-05-20 Corium Inc Microarrays for therapeutic agent delivery, methods of use and manufacturing methods
US10154971B2 (en) 2013-06-17 2018-12-18 Adamas Pharma, Llc Methods of administering amantadine
US10548953B2 (en) 2013-08-14 2020-02-04 Bioverativ Therapeutics Inc. Factor VIII-XTEN fusions and uses thereof
WO2016036866A1 (en) 2014-09-04 2016-03-10 Corium International, Inc. Microstructure array, methods of making, and methods of use
DE102015003254A1 (en) * 2015-03-16 2016-09-22 Fresenius Medical Care Deutschland Gmbh Textile fabric for application to the skin and / or a wound of a patient and transdermal patch and arrangement of a transdermal patch and an evaluation unit
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP6909203B2 (en) 2015-08-03 2021-07-28 バイオベラティブ セラピューティクス インコーポレイテッド Factor IX fusion proteins and their production and usage
WO2017070078A1 (en) 2015-10-22 2017-04-27 The Procter & Gamble Company Barrier patch of a foamed film and methods of improving skin appearance
WO2017070082A1 (en) 2015-10-22 2017-04-27 The Procter & Gamble Company Barrier patch of a foamed film and methods of improving skin appearance
CN105380930A (en) * 2015-12-06 2016-03-09 杨坤英 Burn treatment patch
WO2018071656A1 (en) 2016-10-14 2018-04-19 Knowles Enterprises Inc. Formulations for treatment of migraines
WO2018129496A1 (en) 2017-01-09 2018-07-12 The Procter & Gamble Company Barrier patch with soluble film and methods of improving skin appearance
US10857076B2 (en) 2017-01-09 2020-12-08 The Procter & Gamble Company Barrier patch with soluble film and methods of improving skin appearance
US10751265B2 (en) 2017-01-09 2020-08-25 The Procter & Gamble Barrier patch with soluble film and methods of improving skin appearance
WO2018200885A1 (en) 2017-04-26 2018-11-01 Neurocentria, Inc. Magnesium compositions and methods of use
WO2018237214A1 (en) 2017-06-22 2018-12-27 The Procter & Gamble Company Beauty care films including a water-soluble layer and a vapor-deposited coating
CN111698984B (en) 2018-03-19 2023-11-14 宝洁公司 Method for preparing barrier patch with soluble film

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026552A (en) * 1987-09-25 1991-06-25 L'oreal Sheet material for performing a skin or hair treatment, method for its manufacture, and articles made of this material
US5132115A (en) * 1986-04-17 1992-07-21 Karin Wolter Planar therapeutic system, process for its production and utilization
JPH04244019A (en) * 1991-01-30 1992-09-01 Nitto Denko Corp Patch for medical application
EP0506300A2 (en) * 1991-03-20 1992-09-30 Hydromer, Inc. Tacky, hydrophilic gel dressings and products therefrom
US5161688A (en) * 1988-04-22 1992-11-10 Muchin Jerome D Sampler and method of making the same
EP0559411A1 (en) * 1992-03-04 1993-09-08 Eli Lilly And Company Titratable transdermal patch system and method for administration of therapeutic substances
WO1997017044A1 (en) * 1995-11-03 1997-05-15 Biolaminations Pty. Ltd. Membrane for skin removed wound
DE19844079A1 (en) * 1998-05-22 1999-11-25 Novosis Pharma Ag New four-layer transdermal system

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2629378A (en) * 1951-05-07 1953-02-24 James Frenkil Wet compress and container
US3731683A (en) * 1971-06-04 1973-05-08 Alza Corp Bandage for the controlled metering of topical drugs to the skin
US4022203A (en) * 1976-01-22 1977-05-10 Win Ackley Treated patch for minor cuts
US5468501A (en) 1982-09-01 1995-11-21 Hercon Laboratories Corporation Article useful for administration of pharmacologically-active substances transdermally, orally or by means of implant
US4731926A (en) 1985-02-19 1988-03-22 Drug Delivery Systems Inc. Method of manufacturing disposable and/or replenishable transdermal drug applicators
WO1986000814A1 (en) 1984-07-24 1986-02-13 Key Pharmaceuticals, Inc. Adhesive transdermal dosage layer
CA1272922A (en) 1986-06-03 1990-08-21 Peter William Berry Drug delivery device, its preparation and use
US4812305A (en) * 1987-11-09 1989-03-14 Vocal Rodolfo S Well medicine strip
US4830854A (en) * 1987-12-18 1989-05-16 James B. Copelan Chemical splinter removal
US5223261A (en) 1988-02-26 1993-06-29 Riker Laboratories, Inc. Transdermal estradiol delivery system
US5300291A (en) * 1988-03-04 1994-04-05 Noven Pharmaceuticals, Inc. Method and device for the release of drugs to the skin
DE3910543A1 (en) 1989-04-01 1990-10-11 Lohmann Therapie Syst Lts TRANSDERMAL THERAPEUTIC SYSTEM WITH INCREASED ACTIVE FLUID AND METHOD FOR THE PRODUCTION THEREOF
DE3913734C2 (en) 1989-04-26 1998-08-20 Roehm Gmbh Use of an aqueous skin pressure sensitive adhesive solution for producing an adhesive layer which can be easily washed off with water
US5350581A (en) 1989-12-14 1994-09-27 Pharmetrix Corporation Method for manufacturing transdermal devices
US5512277A (en) * 1991-05-15 1996-04-30 Kao Corporation Keratotic plug remover
US5300299A (en) 1991-07-22 1994-04-05 Dow Corning Corporation Silicone pressure sensitive adhesive containing alkylmethylsiloxane wax and related methods and devices
US5489624A (en) 1992-12-01 1996-02-06 Minnesota Mining And Manufacturing Company Hydrophilic pressure sensitive adhesives
US5962011A (en) * 1993-12-06 1999-10-05 Schering-Plough Healthcare Products, Inc. Device for delivery of dermatological ingredients
US5851549A (en) 1994-05-25 1998-12-22 Becton Dickinson And Company Patch, with system and apparatus for manufacture
US5505958A (en) 1994-10-31 1996-04-09 Algos Pharmaceutical Corporation Transdermal drug delivery device and method for its manufacture
US5546929A (en) 1995-07-07 1996-08-20 Muchin Jerome D Nasal dilator
US5716621A (en) 1996-07-03 1998-02-10 Pharmadyn, Inc. Nonocclusive drug delivery device and process for its manufacture

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5132115A (en) * 1986-04-17 1992-07-21 Karin Wolter Planar therapeutic system, process for its production and utilization
US5026552A (en) * 1987-09-25 1991-06-25 L'oreal Sheet material for performing a skin or hair treatment, method for its manufacture, and articles made of this material
US5161688A (en) * 1988-04-22 1992-11-10 Muchin Jerome D Sampler and method of making the same
JPH04244019A (en) * 1991-01-30 1992-09-01 Nitto Denko Corp Patch for medical application
EP0506300A2 (en) * 1991-03-20 1992-09-30 Hydromer, Inc. Tacky, hydrophilic gel dressings and products therefrom
EP0559411A1 (en) * 1992-03-04 1993-09-08 Eli Lilly And Company Titratable transdermal patch system and method for administration of therapeutic substances
WO1997017044A1 (en) * 1995-11-03 1997-05-15 Biolaminations Pty. Ltd. Membrane for skin removed wound
DE19844079A1 (en) * 1998-05-22 1999-11-25 Novosis Pharma Ag New four-layer transdermal system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE CHEMICAL ABSTRACTS STN; XP002148481 *

Also Published As

Publication number Publication date
US6261593B1 (en) 2001-07-17
AU4460900A (en) 2000-11-02
US6183770B1 (en) 2001-02-06
WO2000062763A2 (en) 2000-10-26

Similar Documents

Publication Publication Date Title
WO2000062763A3 (en) Carrier patch for the delivery of agents to the skin
WO1997006789A3 (en) Transdermal drug delivery device having enhanced adhesion
CA2293528A1 (en) A delivery system for an oral care substance using a strip of material having low flexural stiffness
PL335410A1 (en) Medium for transcutaneous testosterone administration
WO2002092049A3 (en) System for delivering cosmetics and pharmaceuticals
CA2278714A1 (en) Externally mounted medicated nasal dilator
AU6545198A (en) Backup pad for abrasive articles, and method of use
AU7805398A (en) A delivery system for a tooth whitener using a strip of material having low flexural stiffness
WO2005042055A3 (en) Transdermal drug delivery device
CA2350601A1 (en) Wet skin adhesive article
WO1999055312A3 (en) Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces
AU7470898A (en) Methods for forming integrated circuits within substrates, and embedded circui ts
ZA952364B (en) Dressing
ZA977832B (en) Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents.
CA2268187A1 (en) Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces
WO1999012529A3 (en) Transdermal therapeutic system comprising a reservoir-type pressure-sensitive adhesive layer and a back layer with uni-directional resilience
AU4996300A (en) Method of electroporation-enhanced delivery of active agents
AU2001272367A1 (en) A dressing
AU3077499A (en) Over-voltage protection system for integrated circuits using the bonding pads and passivation layer
PL350137A1 (en) Wound dressing
AU4948493A (en) Dexpanthenol-containing plaster for the transdermal application of steroid hormones
GB2349840A (en) Abrasive article and method for making the same
AU5323398A (en) Contour of a transdermal therapeutic system
EP1008330A3 (en) Adhesive bandage
AU2356001A (en) Surface treatment agent for laminated fabric

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP