WO2001013867A1

WO2001013867A1 - Antiperspirant compositions containing isopropyl glycerol ether

Info

Publication number: WO2001013867A1
Application number: PCT/IB2000/000374
Authority: WO
Inventors: David Frederick Swaile
Original assignee: The Procter & Gamble Company
Priority date: 1999-08-24
Filing date: 2000-03-29
Publication date: 2001-03-01
Also published as: AU3317200A; US6083493A

Abstract

The present invention is directed to antiperspirant compositions which comprise from about 0.1 % to about 99.9 % by weight of solubilized or solid antiperspirant active and from about 0.1 % to about 99.9 % by weight of a carrier which comprises isopropyl glycerol ether, preferably in combination with a volatile silicone liquid carrier and dimethiconol as a coupling agent. The isopropyl glycerol ether carrier is a highly effective coupling agent and is milder to the skin when applied topically to the axilla or other areas of the skin as compared to many other polyol-containing carriers. Preferred are antiperspirant compositions containing solubilized antiperspirant active.

Description

ANTIPERSPIRANT COMPOSITIONS CONTAINING ISOPROPYL GLYCEROL ETHER

FIELD OF INVENTION

This mvention relates to antiperspirant compositions comprising antiperspirant active and a earner compnsmg isopropyl glycerol ether This earner is milder to the skin than many other polyol-containing earners, and is especially effective as a couplmg agent for gellant systems containing si cone earners

BACKGROUND OF THE INVENTION

Polyol-containing earners and solvents are well known for use in deodorant and antiperspirant compositions These earners are most typically used to solubilize the antiperspirant active, or as coupling agents during the manufacturing process These polyol earners are typically aliphatic polyhydπc alcohols which have from 2 to 12 carbon atoms, examples of which include ethylene glycol, diethylene glycol, butylene glycol, 1 ,2-proplyene glycol, 1,3-propylene glycol, 1,3-butylene glycol ( 1 ,3-butane-dιol), glycerine ( 1,2,3-tπhydroxy propane), 2-methyl-2,4-pentane-dιol (hexylene glycol), 2-ethyl-l,3-hexane-dιol, 1,2,6- hexanetnol, and combinations thereof Polyol-containing earners are especially useful in formulating a vanety of consumer products containing solubilized antiperspirant active In making such products, the polyol-containing earner is typically m the form of an aqueous system which is used to initially solubilize the antiperspirant active Once the antiperspirant active is solubilized, the water in the aqueous system is removed by any of a vanety of known means The anhydrous solution is then used to formulate an antiperspirant composition containing solubilized antiperspirant active

Polyol-containing earners are especially useful m formulating clear or translucent antiperspirant compositions These compositions are typically anhydrous systems containing solubilized antiperspirant active, wherein the polyol earner is used to help solubilize the active and m most cases provides the primary earner matenal within which the solubilized active is miscible or dispersed within Many polyol-containing earners, however, can cause skin imtation when topically applied to the underarms or other sensitive areas of the skin This skin imtation is especially problematic when the applied composition is an anhydrous system containing higher concentrations of the polyol earner These higher polyol concentrations are often necessary m anhydrous antiperspirant compositions to successfully couple product gellants, structurants, thickening agents or other similar matenals with other product earners or solvents This skin imtation, especially when caused by higher polyol concentrations, is especially problematic in a small percentage of the population that is unusually sensitive to topical polyol imtation Although this type skm imtation can be minimized by addmg lower untation solvents such as mineral oil or volatile sihcones, these low imtation solvents are not miscible with higher concentrations of most high- polanty polyol solvents

It has now been found that polyol-containing carriers, and in particular isopropyl glycerol ether containing earners, can be formulated which cause remarkably less skm irritation It has been found that isopropyl glycerol ether is an excellent couplmg agent that not only causes less skin untation, but that can be used at lower concentrations which further results in reduced skin untation

It is therefore an object of the present invention to provide a polyol-containing annperspirant composition that is milder to the skin, and further to provide such a composition that also has good skm feel characteπstics during and after topical application

SUMMARY OF THE INVENTION

The present invention is directed to annperspirant compositions compnsmg from about 0 1 % to about 99 9% by weight of antiperspirant active and from about 0 1% to about 99 9% by weight of a earner compnsmg isopropyl glycerol ether The antiperspirant active may be solubilized or in the form of a particulate solid

It has now been found that the selection of isopropyl glycerol ether as a solvent or coupling agent in an antiperspirant composition provides the composition with unproved performance relative to most polyol- containing solvents known for use in antiperspirant compositions In particular, this select polyol is milder to the skm than many other similar polyol-containing solvents As compared to other diol solvents, isopropyl glycerol ether is especially effective as a couplmg agent in antiperspirant compositions, especially those compositions that compnse a solid gellant and a volatile silicone solvent The isopropyl glycerol ether solvent is especially effective at couplmg the solid gellant and the volatile silicone solvent mto a smgle phase system It has also been found that the antiperspirant compositions of the present invention provide unproved skin feel performance, aesthetics, and/or product stability as compared to other polyol-containing antiperspirant compositions

DETAILED DESCRIPTION The antiperspirant compositions of the present mvention include antiperspirant compositions in final or intermediate product form, and mclude product forms such as solids or gel solid sticks, soft solids or creams, lotions or other liquids, aerosol or pump sprays, and so forth These antiperspirant compositions are intended for topical application to the underarm or other suitable areas of the skm, or as manufacturing intermediates The term "ambient conditions" as used herein refers to surrounding conditions under about one atmosphere of pressure, at about 50% relative humidity, and at about 25°C The term "volatile" as used herein refers to those matenals which have a measurable vapor pressure as measured at 25°C Such vapor pressures will typically range from about 0 01 rnmHg to about 6 mmHg, more typically from about 0 02 mmHg to about 1 5 mmHg, and have an average boiling point at one atmosphere of pressure (1 atm) typically less than about 250°C, more typically less than about 235°C, at 1 atmosphere (atm) of pressure

All percentages, parts and ratios as used herem are by weight of the total composition, unless otherwise specified All such weights as they pertain to listed ingredients are based on the active level and, therefore, do not include solvents or by-products that may be mcluded m commercially available matenals, unless otherwise specified The antiperspirant compositions of the present invention can compnse, consist of, or consist essentially of the essential elements and limitations of the mvention descnbed herem, as well as any of the additional or optional ingredients, components, or limitations descnbed herem

Liquid Carrier The annperspirant compositions of the present mvention compnses from about 0 1% to about 99 9% by weight of a liquid earner compnsmg isopropyl glycerol ether, preferably a liquid earner compnsmg a combmation of isopropyl glycerol ether and one or more other known or otherwise effective liquid earner matenals The earner is a liquid under ambient conditions, and therefore includes earner liquid combinations or combinations of earner liquids and dissolved earner solids, provided that any such combmation is m liquid form under ambient conditions

The antiperspirant compositions of the present mvention may be formulated as an aqeuous or anhydrous composition For an aqueous formulation, the antiperspirant compositions may further compnse from about 10% to about 75% by weight of water, preferably from about 10% to about 60% by weight of water, even more preferably from about 20% to about 50%, by weight of water For an anhydrous formulation, antiperspirant compositions contain less than about 20%, more preferably less than about 5%, even more preferably less than about 3%, even more preferably less than about 1%, most preferably zero percent, by weight of free or added water

The concentration of isopropyl glycerol ether m the antiperspirant composition of the present invention ranges from about 0 1% to about 99 9% by weight of the annperspirant composition, but specific isopropyl glycerol ether concentrations may vary greatly dependmg upon vanables such as 1) the function to be served by the isopropyl glycerol ether, 2) the desired product form, viscosity, and hardness of the antiperspirant composition, 3) whether the antiperspirant composition is m final or intermediate form, and 4) other formulation vanables well know m the chemical or formulation arts For most product forms, the concentration of isopropyl glycerol ether in the antiperspirant composition ranges from about 0 1% to about 70%, more preferably from about 1% to about 40%, even more preferably from about 5% to about 25%, by weight of the composition In addition to the isopropyl glycerol ether earner, the antiperspirant compositton may further comprise one or more optional liquid earners suitable for topical application and appropnate for the product form desired Such other optional earners mclude any known or otherwise effective liquid earner matenal for use in antiperspirants, deodorants or other topical compositions In the event that the optional liquid carrier is not readily miscible or dispersible m isopropyl glycerol ether or other materials m the liquid camer component, then other liquid earners or couplmg agents may be added to the composition to bring the isopropyl glycerol ether and other immiscible or nondispersible materials (e g , nonpolar solvents) mto a homogenous solution or dispersion In this context, it has been found that silicone containing earners or couplmg agents, especially silicone earners havmg one or more hydroxyl groups, e g , dimethiconols as described hereinafter, are especially useful as additional liquid earners or couplmg agents

The antiperspirant composition of the present mvention is preferably anhydrous In this context, the term "anhydrous" means that the composition contains less than about 10%, more preferably less than about 5%, even more preferably less than about 3%, even more preferably less than about 1%, most preferably zero percent, by weight of free or added water, excludmg any water of hydration typically associated with antiperspirant active when formulated m the form of particulate solids, and excludmg any water of hydration typically associated with any other added solids

The preferred concentration of liquid earners m the antiperspirant composition will vary with the selected product form In this context, the term "liquid earners" refers to the combmation of isopropyl glycerol ether and any optional earner liquids For most product forms, mcludmg solid sticks or soft solid sticks or creams, liquid camer concentrations preferably range from about 10% to about 90%, more preferably from about 30% to about 70%, even more preferably from about 45% to about 70%, by weight of the antiperspirant composition For aerosol concentrates, pump sprays, roll-on and other liquid product forms, the liquid earner concentration preferably ranges from about 50% to about 99%, more preferably from about 60% to about 98%, even more preferably from about 75% to about 98%, by weight of the composition Aerosol concentrates may further compnse a propellant to form the desired aerosol spray product

The antiperspirant compositions of the present mvention mclude final and intermediate product forms, and such forms can have a wide range of viscosity and physical charactenstics dependmg on whether the product form is a solid, soft sold, cream, lotion, aerosol, pump spray, and so forth Optional liquid earners for use m combmation with isopropyl glycerol ether m the antiperspirant composition of the present mvention includes any topically safe and effective organic, si cone-containing or fluorine-containing, volatile or non-volatile, polar or non-polar earner liquid, provided that the resulting combmation of earner matenals form a solution or other homogenous liquid or liquid dispersion at the selected processmg temperature of the composition Processing temperatures for the antiperspirant compositions typically range from about 28°C to about 250°C, more typically from about 28°C to about 110 °C, and even more typically from about 28°C to about 100°C The antiperspirant composition of the present mvention preferably further compnses dimethiconol as an optional liquid earner Prefened concentrations of the dimethiconol range from about 0 1%_> to about

50%, more preferably from about 1% to about 35%, even more preferably from about 2% to about 20%, by weight of the composition Dimethiconols suitable for use as the prefened optional liquid camer mclude those coπesponding to the formula.

wherein n is number havmg a value of zero or greater, preferably from about 1 to about 100, more preferably from about 1 to about 50, even more preferably from about 1 to about 10. Nonlimiting examples of suitable dimethiconols mclude Masil® SFR 70, Mazol® SFR 18,000, Mazol® SFR 50,000, Mazol® SFR 100, Mazol® SFR 150,000, Mazol® SFR 750, Mazol® SFR 2000, and Mazol® SFR 3500, all available from PPG/Specialty Chemicals; and Umsil SF-R available from Umversal Preservative. Other available dimethiconols mclude Abil® OSW 12, OSW13, Abil® OSW 15, and Abil® CK, all available from Goldschmidt, Dow Corning® 1401 Fluid, Dow Corning® Q2-1403 Fluid both available from Dow Corning, and Tπ-Sil HGC 5000 available from Tn-K Industnes.

Other preferred but optional liquid earners mclude PPG-3-mynstyl ether, dnsopropyl adipate, PPG- 14 butyl ether, dimethicone copolyols, and combinations thereof, especially m combmation with a dimethiconol as descnbed above

Other optional liquid earners mclude modified or organofunctional silicone earners such as polyalkylsiloxanes, polyalkyarylsiloxanes, polyestersiloxanes, polyethersiloxane copolymers, polyfluorosiloxanes, polyaminosiloxanes, and combinations thereof. These modified silicone earners are typically liquid under ambient conditions, and have a prefened viscosity of less than about 100,000 centistokes, more preferably less than about 500 centistokes, even more preferably from about 1 cenUstoke to about 50 centistokes, and most more preferably from about 1 centistoke to about 20 centistokes These modified silicone earners are generally known in the chemical arts, some examples of which are descnbed m 1 Cosmetics, Science and Technology 27-104 (M. Balsam and E. Sagarin ed. 1972); U.S. Patent 4,202,879, issued to Shelton on May 13, 1980; U.S. Patent 5,069,897, issued to Orr on December 3, 1991 ; which descnptions are incorporated herem by reference.

Suitable modified silicone earners mclude, but are not limited to, compounds or matenals such as those defined hereinabove and which are generally characterized as follows: silicone polyethers or silicone glycols (such as dimethicone copolyol); silicone alkyl-linked polyethers (such as Goldschmidt EM-90 or EM-97); siloxane surfactants of a pendant/rake/comb configuranon, silicone surfactants of a tnsiloxane configuration, and silicone surfactants of an ABA/alpha-omega block copolymers (such as polyoxyalkylenes, polyoxyethylene or ethoxylated, polyoxyethylene/polyoxypropylene or ethoxylated/propoxylated); aromatic substituted silicone emollients (such as phenyl, alpha-methyl styryl, styryl, methylphenyl, alkylphenyl), silicone copolymers with other functional groups mclude: hydrogen, alkyl. methyl, ammo, tnfluoropropyl, vmyl, alkoxy, arylalkyl, aryl, phenyl, styryl, polyethers, esters, carboxylics, alkylmethyl siloxanes or silicone waxes (such as hexyl, octyl, lauryl, cetyl, stearyl); nomonic functional siloxane copolymers with terminal groups bemg silanol or tnmethylsiloxy; nomomc functional siloxanes with backbone groups bemg tnsiloxane or methicone linked; nomomc silicone surfactants, tetraethoxysilane; tetramethoxysilane, hexamethoxysilicone, oxmethoxytnsiloxane, silicone emulsifϊers; silicone or siloxane resins, alkyl silicone resms, polyoxyalkylene silicone resins; MQ Resins such as Shiseido/Shin-etsu ,e.g Japanese Patent Publication JP86143760 or from Walker Chem. 6MBH (descnbed in EP722970); alkoxysiloxanes. alkoxysilanes; methicones (polymethylalkylsiloxanes); and combinations thereof

Nonlimiting examples of suitable modified silicone earners for use m the annperspirant compositions herem mclude the following modified si cones available from Dow Corning: DC-556 Cosmetic Grade Fluid (phenyl tnmethicone), DC-704 Diffusion Pump Fluid (Tetramethyl-Tetraphenyl- Tπsiloxane), DC-705 Diffusion Pump Fluid; DC- 1784 Emulsion, DC-AF Emulsion; DC-1520-US Emulsion, DC-593 Fluid (Dimethicone [and] Tnmethylsiloxysilicate); DC-3225C Fluid (Cyclomethicone [and] Dimethicone Copolyol), DC-190 Fluid (Dimethicone Copolyol); DC-193 Fluid (Dimethicone Copolyol), DC- 1401 (Cyclomethicone [and] Dimethiconol); DC-5200 Fluid (Laurylmethicone Copolyol); DC-6603 Polymer Powder; DC-5640 Powder, DC-Q2-5220 (Dimethicone Copolyol); DC Q2-5324 (Dimethicone Copolyol); DC-2501 Cosmetic Wax (Dimethicone Copolyol), DC-2502 Fluid (Cetyl Dimethicone), DC-2503 Wax (Stearyl Dimethicone); DC- 1731 Volatile Fluid (Caproyl Tnmethicone); DC- 580 Wax (Stearoxytnmethylsilane [and] Stearyl Alcohol); DC-1-3563 (Dimethiconal); DC-X2-1286 (Dimethiconol), DC-X2-1146A (Cylcomethicone [and] Dimethiconol); DC-8820 Fluid (Ammo funcnonalized), DC Q5-0158A wax (stearoxytnmethylsilane); DC-Q2-8220

(Trimethylsilylamodimefhicone), DC-7224 (Tnmethylsilylamodimethicone); DC-X2-1318 Fluid (Cyclomethicone [and] Vinyldimethicone); DC-QF1-3593A fluid (Tnmethylsiloxysilicate) and combinations thereof. Other nonlimiting examples of suitable modified silicone earners for use m the antiperspirant compositions herem mclude the following modified sihcones available from General Electnc: GE SF-1023 (Dimethyl-Diphenyl-Siloxane); GE CF-1142 (Methylphenyl Siloxane Fluid); GE SF-1153 (Dunethyl- Dφhenyl-Siloxane); GE SF-1265 (Dφhenyl-Dimethyl-Siloxane); GE SF-1328; GE SF-1188 (Dimethicone copolyol); GE SF-1188A (Silicone polyether copolymer), GE SF-1288 (silicone polyether copolymer, dimethyl-methyl 3-hydroxypropyl ethoxylated); GE SF-1318 (Methylester Siloxane); GE SF-1328 (silicone surfactant, dimethyl-methyl 3-hydroxypropyl ethoxylated-propoxylated); GE SF-1550 (methylphenyl siloxane, hexamethyl-3-phenyl-3-[[tnmethylsιlyl]oxy]tnsιloxane), GE SF-1632 (silicone wax), GE SS-4267 (Dimethicone [and] Tnmethylsiloxysilicate) and combinations thereof

Other nonlimiting examples of suitable modified silicone earners for use m the antiperspirant compositions herem mclude the following modified sihcones available from Goldschmidt Abil EM-90 (silicone emulsifier), Abil EM-97 (polyether siloxane), Abil Wax 9810 (silicone wax or C24-28 methicone), Abil Wax 2434 (Stearoxy Dimethicone), Abil Wax 9800D (Stearyl Dunethicone), Tegomer H-Si 2111, H-Si 231 1, A-Si 2120, A-Si 2320, C-Si 2141, C-Si 2341, E-Si 2130, E-Si 2330, V-Si 2150, V-Si 2550, H-Si 6420, H-Si 6440, H-Si 6460 (Alpha-Omega Dimethicone Copolymers) and combmations thereof

Other nonlimiting examples of suitable modified silicone earners for use m the antiperspirant compositions herein mclude the following Masil 756 from PPG Industnes (Tetrabutoxypropyl Tπsiloxane), bis-phenylhexamethicone (available as Silbione Oils 70633 V30 from Rhone-Poulenc), Silbione Oils 70646 (dunethicone copolyols from Rhone-Poulenc), Silicone L-71 1, L-720, L-721 and L722 (dunethicone copolyols from Umon Carbide), Silicone L-7000, L-7001, L-7002, L-7004, L-7500, L-7600, L-7602, L-7604, L-7605, and L-7610 (dunethicone copolyols from Umon Carbide), Umsil SF-R (dimethiconol from UPI), Silicate Cluster from Olm (Tπs[tnbutoxysιloxy]methylsιlane), silicone copolymer F-754 (dimethicone copoly from SWS Sihcones), and combmations thereof

The annperspirant composition of the present mvention preferably compnses a volatile silicone earner m combmanon with isopropyl glycerol ether The concentration of the volatile silicone preferably range from about 10% to about 90%, more preferably from about 15% to about 65%, by weight of the antiperspirant composition These volatile silicone earners may be cyclic, linear or branched cham sihcones having the requisite volatility defined herem Non-limiting examples of suitable volatile sihcones are descnbed m Todd et al , "Volatile Silicone Fluids for Cosmetics", Cosmetics and Toiletnes, 91 27-32 (1976), which descπpnons are incorporated herem by reference Prefened among these volatile sihcones are the cyclic sihcones havmg from about 3 to about 7, more preferably from about 4 to about 5, silicon atoms Most preferably are those which conform to the formula

wherem n is from about 3 to about 7, preferably from about 4 to about 5, most preferably 5 These volatile cyclic sihcones generally have a viscosity value of less than about 10 centistokes All viscosity values descnbed herem are measured or determined under ambient conditions, unless otherwise specified Suitable volatile sihcones for use herem mclude, but are not limited to, Cyclomethicone D-5 (commercially available from G E Sihcones), Dow Corning 344, and Dow Corning 345 (commercially available from Dow Corning Corp ), GE 7207, GE 7158 and Silicone Fluids SF-1202 and SF-1173 (available from General Electric Co ), SWS-03314, SWS-03400, F-222, F-223, F-250, F-251 (available from SWS Sihcones Corp ), Volatile Sihcones 7158, 7207, 7349 (available from Union Carbide), Masil SF-V ( available from Mazer) and combmations thereof.

Optional liquid earners may also mclude a non-volatile silicone earner other than or m addition to the preferred modified silicone carriers descnbed herembefore. These non-volatile silicone earners are preferably lmear sihcones which mclude, but are not limited to, those which conform to either of the formulas

wherem n is greater than or equal to 1 These lmear silicone matenals will generally have viscosity values of up to about 100,000 centistoke, preferably less than about 500 cennstoke, more preferably from about 1 centistoke to about 200 centistoke, even more preferably from about 1 centistoke to about 50 cennstoke, as measured under ambient conditions. Examples of non-volatile, lmear sihcones suitable for use m the antiperspirant compositions mclude, but are not limited to, Dow Corning 200, hexamethyldisiloxane, Rhodorsil Oils 70047 available from Rhone-Poulenc, Masil SF Fluid available from Mazer, Dow Corning 225, Dow Corning 1732, Dow Corning 5732, Dow Corning 5750 (available from Dow Corning Corp ); SF- 96, SF-1066 and SF 18(350) Silicone Fluids (available from G.E. Sihcones); Velvasil and Viscasil (available from General Electnc Co.); and Silicone L-45, Silicone L530, Silicone L-531 (available from Umon Carbide), and Siloxane F-221 and Silicone Fluid SWS-101 (available from SWS Sihcones).

The antiperspirant composition preferably compnses a combmation of volatile and nonvolatile silicone materials, more preferably a combmation of volatile and nonvolatile silicone camer liquids. Nonlimiting examples of suitable combinations of such silicone matenals are descnbed in U.S. Patent 5,156,834 (Beckmeyer et al.), which descnptions are incorporated herem by reference.

Optional liquid earners for use in combmanon with the isopropyl glycerol ether may also mclude mono and polyhydnc alcohols (e.g., 1,2-hexanedιol), fatty acids, esters of mono and dibasic carboxyhc acids with mono and polyhydnc alcohols, polyoxyethylenes, polyoxypropylenes, polyalkoxylates ethers of alcohols, and combmations thereof. Preferably such optional liquid earners are also water-rmmiscible liquids under ambient conditions. Other suitable water-immiscible, polar organic liquid earners or solvents for use m combmation with the isopropyl glycerol ether are descnbed in Cosmetics, Science, and Technology, Vol. 1, 27-104, edited by Balsam and Sagarin (1972); U.S. Patent 4,202,879 issued to Shelton on May 13, 1980; and U.S Patent 4,816,261 issued to Luebbe et al. on March 28, 1989, which descnptions are incorporated herem by reference.

Other optional liquid earners for use in combmation with the isopropyl glycerol ether mclude anhydrous, water-miscible, polar orgamc liquid earners or solvents, examples of which mclude short chain alcohols such as ethanol and glycol solvents such as propylene glycol, hexylene glyol, dipropylene glycol, tπpropylene glycol, and so forth. Other suitable similar solvents also mclude polyalkoxylated earners such as polyethylene glycols, polyproylene glycols, combmations and denvatives thereof, and so forth. Non- limiting examples of polar solvents suitable for use herem are descnbed m U.S Patent 5,429,816 Other suitable polar solvents mclude phthalate co-solvents, benzoate co-solvents, cmnamate esters, secondary alcohols, benzyl acetate, phenyl alkane and combmations thereof

Optional liquid earners for use m combmation with the isopropyl glycerol ether may also mclude non-polar earners such as mineral oil, petrolatum, isohexadecane, lsododecane, vanous hydrocarbon oils such as the Isopar or Norpar senes available from Exxon Corp. or Permethyl senes available from Persperse, and the Soltrol senes available from Phillips Chemical, and any other polar or non-polar, water- miscible, organic earner liquid or solvent known or otherwise safe and effective for topical application to human skm

Other optional liquid earners for use m combmation with the isopropyl glycerol ether includes fluorochemicals such as fluorosurfactants, fluorotelemers, and perfluoropolyethers, some examples of which are descnbed m Cosmetics & Toiletnes, Usmg Fluonnated Compounds m Topical Preparations, Vol. I l l, pages 47-62, (Oct. 1996) which descπption is incorporated herem by reference More specific examples of such liquid earners mclude, but are not limited to, perfluoropolymethyl isopropyl ethers, perfluoropolypropylethers, acrylamide fluonnated telomer, fluonnated amide surfactants, perfluonnated thiol surfactants. Other more specific examples mclude, but are not limited to, the polyperfluoroisopropyl ethers available from Dupont Performance Chemicals under the trade name Fluortress ® PFPE oils, and the series fluorosurfactants from Dupont Performance Chemicals under the trade name Zonyl ® Fluorosurfactants.

Antiperspirant Active The antiperspirant compositions of the present mvention compnse an annperspirant active suitable for application to human skm. The actives may be solubilized m the composition or may be suspended as undissolved or precipitated solids. The concentration of antiperspirant active m the composinon should be sufficient to provide the desired perspiration wetness and odor control.

The antiperspirant compositions of the present mvention compnse antiperspirant active at concentrations of from about 0.1% to about 99.9%, preferably from about 0.5% to about 50%, more preferably from about 5% to about 35%, even more preferably from about 6% to about 26%, by weight of the composition. All such weight percentages are calculated on an anhydrous metal salt basis exclusive of water and any complexmg agents such as glycine, glycme salts, or other complexing agents.

The antiperspirant active may be formulated as paniculate solids m the form of dispersed solid particles having a preferred average particle size or diameter of less than about 100 μm, more preferably from about 15 μm to about 100 μm, even more preferably from about 20 μm to about 100 μm. Also prefened are dispersed solid partieulates havmg an average particle size or diameter of less than about 2 μm, even more preferably from less than about 0.4 μm.

The antiperspirant active for use m the annperspirant compositions of the present mvention mclude any compound, composition or other material having antiperspirant activity. Prefened annperspirant actives mclude the astringent metallic salts, especially the inorganic and orgamc salts of aluminum, zirconium and zmc, as well as mixtures thereof Particularly prefened are the alummum and zirconium salts, such as aluminum hahdes, alummum chlorohydrate, alummum hydroxyhahdes, zirconyl oxyha des, zirconyl hydroxyhahdes, and mixtures thereof.

Prefened alummum salts for use in the antiperspirant compositions mclude those which conform to the formula-

Al₂(OH)_a Cl _b x H₂0 wherein a is from about 2 to about 5, the sum of a and b is about 6; x is from about 1 to about 6; and wherem a, b, and x may have non-mteger values. Particularly prefened are the alummum chlorhydroxides refened to as "5/6 basic chlorhydroxide", wherem a = 5, and "2/3 basic chlorhydroxide", wherem a = 4. Processes for preparing alummum salts are disclosed m U.S. Patent 3,887,692, Gilman, issued June 3, 1975; U.S. Patent 3,904,741, Jones et al., issued September 9, 1975; U.S. Patent 4,359,456, Goslmg et al., issued November

16, 1982; and Bntish Patent Specification 2,048,229, Fitzgerald et al., published December 10, 1980, all of which are incorporated herem by reference. Mixtures of alummum salts are descnbed m Bntish Patent Specification 1,347,950, Shin et al , published February 27, 1974, which descnption is also incorporated herem by reference.

Prefened zirconium salts for use in the antiperspirant compositions mclude those which conform to the formula:

ZrO(OH)_2-aCl_a • x H₂0 wherem a is any number havmg a value of from about 0 to about 2; x is from about 1 to about 7; and wherein a and x may both have non-mteger values. These zirconium salts are descnbed m Belgian Patent 825, 146, Schmitz, issued August 4, 1975, which descnpnon is incorporated herem by reference. Particularly prefened zirconium salts are those complexes which additionally contain aluminum and glycme, commonly known as ZAG complexes. These ZAG complexes contain aluminum chlorhydroxide and zirconyl hydroxy chlonde conforming to the above descnbed formulas. Such ZAG complexes are descnbed in U.S. Patent 3,679,068, Luedders et al., issued February 12, 1974; Great Bntam Patent Application 2,144,992, Callaghan et al., published March 20, 1985; and U S. Patent 4,120,948, Shelton, issued October

17, 1978, all of which are incorporated herem by reference.

The antiperspirant compositions of the present mvention can also be formulated to compnse other active matenals m addition to or m place of the annperspirant active descnbed herem. Such other active materials can likewise be dissolve or suspended solids, and mclude any active matenal known or otherwise suitable for topical application to human skm, for example deodorant active and/or perfumes as descnbed hereinafter

The antiperspirant compositions of the present mvention may compnse solubilized antiperspirant active, preferably solubilized antiperspirant active m an anhydrous system The concentration of solubilized antiperspirant active m the composition preferably ranges from about 0 1% to 35%, more preferably from about 0 5% to about 25%, even more preferably from about 1% to about 17%, even more preferably from about 6% to about 17%, by weight of the antiperspirant composition ( weight percentages calculated on an anhydrous metal salt basis exclusive of water and any complexing agents such as glycme, glycine salts, or other complexmg agents) It has been found that such anhydrous compositions have good application and aesthetic charactenstics, and with respect to other solubilized active compositions, are typically less sticky during or after application and are milder to the skm It has also been found that solutions of solubilized antiperspirant active and isopropyl glycerol ether are more compatible with nonpolar solvents, even when the latter is used at higher concentrations This now allows for the formulation of clear or translucent antiperspirant compositions containing nonpolar solvents such as volatile and nonvolatile sihcones

Suspending or thickening agent The antiperspirant compositions of the present mvention may further compnse a suspendmg or thickemng agent to help provide the composition with the desired viscosity or product hardness, or to otherwise help suspend any dispersed solids or liquids within the composition Suitable suspendmg or thickemng agents mclude any matenal known or otherwise effective m providmg suspendmg or thickemng properties to the composition, or which otherwise provide structure to the final product form These suspendmg or thickemng agents mclude gelling agents, and polymenc or nonpolymenc or inorganic thickemng or viscosifymg agents Such matenals will most typically mclude orgamc solids, silicone solids, crystalline or other gellants, inorganic partieulates such as clays or silicas, or combmations thereof The concentration and type of the optional suspendmg or thickemng agent selected for use m the antiperspirant composition will vary dependmg upon the desired product form, viscosity, and hardness. For most suspendmg or thickemng agents suitable for optional use herem, the concentration of such suspendmg or thickemng agents will most typically range from about 0 1% to about 35%, more typically from about 0 1% to about 20%), by weight of the composition Suitable gelling agents for use as optional suspendmg or thickemng agents m the antiperspirant composition mclude, but are not limited to, fatty acid gellants, hydroxy acid gellants, esters and amides of fatty acid or hydroxy fatty acid gellants, cholesterohc matenals, dibenzyhdene alditols, lanolinohc matenals, and other amide and polyamide gellants.

Suitable gelling agents mclude fatty alcohols havmg from about 8 to about 40 carbon atoms, preferably from 8 to about 30 carbon atoms, more preferably from about 12 to about 18 carbon atoms These gelling agents are wax-like matenals which are most typically used at concentrations rangmg from about 1% to about 25%, preferably from about 5% to about 20%, most preferably from about 10% to about 20%, by weight of the antiperspirant composition Prefened are cetyl alcohol, mynstyl alcohol, stearyl alcohol and combmations thereof, more preferably stearyl alcohol

Other suitable gellmg agents mclude waxes or wax-like materials havmg a melt point of above 65°C, more typically from about 65°C to about 130°C, examples of which include, but are not limited to, waxes such as beeswax, carnauba, baysberry, cande lla, montan, ozokente, ceresm, hydrogenated castor oil (castor wax), synthetic waxes, microcrystalline waxes Castor wax is prefened within this group Other high melting pomt waxes are descnbed m U S Patent 4,049,792, Elsnau, issued September 20, 1977, which descnption is incorporated herem by reference

Other suitable gellmg agents mclude fatty acid gellants such as fatty acid and hydroxy or alpha hydroxy fatty acids, havmg from about 10 to about 40 carbon atoms, and esters and amides of such gellmg agents Non-limiting examples such gellmg agents mclude 12-hydroxysteanc acid, 12-hydroxylaunc acid, 16-hydroxyhexadecanoιc acid, behemc acid, eurcic acid, steanc acid, capry c acid, launc acid, isosteanc acid, and combmations thereof Prefened are 12-hydroxysteanc acid, esters of 12-hydroxysteanc acid, amides of 12-hydroxysteanc acid and combmations thereof, and all other gellmg agents which conespond to the following formula

wherem R_jis OR N R3 , or a silicone containing moiety, and R₂ and R3 are hydrogen, or an alkyl, aryl, or arylalkyl radical which is branched lmear or cyclic and has from about 1 to about 22 carbon atoms, preferably, from about 1 to about 18 carbon atoms R₂ and R3 may be either the same or different, however, at least one is preferably a hydrogen atom Prefened among these gellants are those selected from the group consisting of 12-hydroxysteanc acid, 12-hydroxysteanc acid methyl ester, 12-hydroxysteanc acid ethyl ester, 12-hydroxysteanc acid stearyl ester, 12-hydroxysteanc acid benzyl ester, 12-hydroxysteanc acid amide, isopropyl amide of 12-hydroxysteanc acid, butyl amide of 12-hydroxysteanc acid, benzyl amide of

12-hydroxysteanc acid, phenyl amide of 12-hydroxysteanc acid, t-butyl amide of 12-hydroxysteanc acid, cyclohexyl amide of 12-hydroxysteanc acid, 1-adamantyl amide of 12-hydroxysteanc acid, 2-adamantyl amide of 12-hydroxysteanc acid, dnsopropyl amide of 12-hydroxysteanc acid, and mixtures thereof, even more preferably, 12-hydroxysteanc acid, isopropyl amide of 12-hydroxysteanc acid, and combmations thereof Most prefened is 12-hydroxysteanc acid

Suitable amide gellants mclude disubstituted or branched monoamide gellants, monosubstituted or branched diamide gellants, tnamide gellants, and combmations thereof, mcludmg n-acyl ammo acid derivatives such as n-acyl ammo acid amides, n-acyl ammo acid esters prepared from glutamic acid, lysme, glutamme, apartic acid, and combmations thereof Other suitable amide gellmg agents are descnbed m U S Patent 5,429,816, issued July 4, 1995, and U S Patent Application Senal Number 08/771,183, filed December 20, 1996, which descnptions are incorporated herem by reference Concentrations of all such gellmg agents preferably range from about 0 1% to about 25%, preferably of from about 1% to about 15%, more preferably from about 1% to about 10%, by weight of the antiperspirant composition

Other suitable gellmg agents mclude tnglycende gellant systems which comprise glyceryl tnbehenate and other tnglyeendes, wherem at least about 75%, preferably about 100%, of the estenfied fatty acid moieties of said other tnglyeendes each have from about 18 to about 36 carbon atoms, and wherem the molar ratio of glyceryl tnbehenate to said other tnglyeendes is from about 20 1 to about 1 1, preferably from about 10 1 to about 3 1, more preferably from about 6 1 to about 4 1 The estenfied fatty acid moieties may be saturated or unsaturated, substituted or unsubstituted, lmear or branched, but are preferably lmear, saturated, unsubstituted ester moieties denved from fatty acid matenals havmg from about 18 to about 36 carbon atoms The tnglycende gellant matenal preferably has a melting pomt of at less than about 110°C, preferably between about 50°C and 110°C

Prefened concentrations of the above-described tnglycende gellant systems range from about 0 1% to about 20%, more preferably from about 0 5% to about 15%, by weight of the antiperspirant composition For roll-on formulations havmg a penetration force value of from about 20 gram force to about 100 gram force, tnglycende concentrations preferably range from about 1% to about 5% by weight of the antiperspirant composition For other cream formulations, mcludmg those formulations suitable for use in cream applicator devices, which have a penetration force value of from about 100 gram force to about 500 gram force, tnglycende concentrations preferably range from about 4% to about 20%, more preferably from about 4% to about 10%, by weight of the antiperspirant composition Specific examples of tnglycende gellmg agents for use m the antiperspirant compositions that are commercially available mclude, but are not limited to, tnsteaπn, hydrogenated vegetable oil, tnhydroxystenn (Thixcin® R, available from Rheox, Inc ), rape seed oil, castor wax, fish oils, tnpalmiten, Syncrowax® HRC and Syncrowax® HGL-C (Syncrowax® available from Croda, Inc )

Other suitable suspendmg or thickemng agents for use m the antiperspirant composition mclude particulate suspendmg or thickemng agents such as clays and colloidal pyrogemc silica pigments Other known or otherwise effective particulate suspendmg or thickemng agents can likewise be used in the antiperspirant composition Concentrations of optional particulate thickemng agents preferably range from about 0 001%) to about 15%, more preferably from about 1% to about 15%, even more preferably from about 1% to about 8%, by weight of the composition Colloidal pyrogemc silica pigments are prefened, a common example of which mcludes Cab-O-Sil ®, a submicroscopic particulated pyrogemc silica Suitable clay suspendmg or thickemng agents mclude montmonllonite clays, examples of which mclude bentomtes, hectontes, and colloidal magnesium aluminum silicates These and other suitable clay suspending agents are preferably hydrophobically treated, and when so tteated will generally be used in combination with a clay activator. Non-limiting examples of suitable clay activators include propylene carbonate, ethanol, and combinations thereof. The amount of clay activator will typically range from about 25% to about 75% by weight of the clay, more typically from about 40% to about 60% by weight of the clay.

Optional Deodorant Active and Fragrance The antiperspirant compositions of the present invention may further comprise a deodorant active, fragrance or combination thereof at concentrations ranging from about 0.001% to about 50%, preferably from about 0.01% to about 20%, more preferably from about 0.1 % to about 10%, by weight of the composition. These deodorant actives and perfumes may be used in addition to or in place of some or all of the antiperspirant active material, and include any known or otherwise safe and effective deodorant or fragrance suitable for topical application to human skin.

Deodorant actives suitable for use in the composition of the present invention includes any topical material that is known for or is otherwise effective in preventing or eliminating malodor associated with perspiration, other than those active materials described hereinbefore. These deodorant actives are typically antimicrobial agents (e.g., bacteriocides, fungicides), malodor-absorbing material, or combinations thereof. Prefened deodorant actives are antimicrobial agents, non-limiting examples of which include cetyl- trimethylammonium bromide, cetyl pyridinium chloride, benzethonium chloride, diisobutyl phenoxy ethoxy ethyl dimethyl benzyl ammonium chloride, sodium N-lauryl sarcosine, sodium N-palmethyl sarcosine, lauroyl sarcosine, N-myristoyl glycine, potassium N-lauryl sarcosine, trimethyl ammonium chloride, sodium aluminum chlorohydroxy lactate, triethyl citrate, tricetylmethyl ammonium chloride, 2,4,4'-trichlorio-2'- hydroxy diphenyl ether, 3,4,4'-trichlorocarbanilide, diaminoaUcyl amides such as L-lysine hexadecyl amide, heavy metal salts of citrate, salicylate, and piroctose, especially zinc salts, and acids thereof, heavy metal salts of pyrithione, especially zinc pyrithione, zinc phenolsulfate, farnesol, and combinations thereof.

Other optional deodorant actives include odor-absorbing materials such as carbonate and bicarbonate salts, including alkali metal carbonates and bicarbonates, ammonium and tettaalkylammonium Prefened are sodium and potassium salts of such odor-absorbing materials.

The antiperspirant composition of the present invention may optionally comprise fragrances suitable for use in a topical composition, and includes any topical material that is known for or is otherwise effective in masking malodor associated with perspiration, or which otherwise provides the composition with the desired perfumed aroma. These fragrances include any perfume or perfume chemical suitable for topical application to the skin. The concentration of the optional fragrance should be effective to provide the desired aroma charactenstics or to mask malodor, wherem the malodor is inherently associated with the composition itself or is associated with malodor development from human perspiration Also, the fragrance and whatever earners accompany it preferably do not impart excessive stmgmg to the skm, especially broken or irntated skm, at the levels previously disclosed The fragrance will typically be in the form of water insoluble perfumes that are solubilized in the matnx of the composition

Fragrances are made by those skilled m the art m a wide vanety of fragrances and strengths Typical fragrances are descnbed m Arctander, Perfume and Flavour Chemicals (Aroma Chemicals), Vol I and II (1969), and Arctander, Perfume and Flavour Matenals of Natural Ongm (1960) U S Patent 4,322,308 and U S Patent 4,304,679, both mcorporated herem by reference, disclose fragrance components as generally mcludmg, but are not limited to, volatile phenolic substances (such as iso-amyl sahcylate, benzyl sahcylate, and thyme oil red), essence oils (such as geranium oil, patchouli oil, and petitgrain oil), citrus oils, extracts and resms (such as benzoin siam resmoid and opoponax resinoid), "synthetic" oils (such as Bergamot 37 and 430, Geranium 76 and Pomeransol 314), aldehydes and ketones (such as B-methyl naphthyl ketone, p-t-butyl-A-methyl hydrocmnamic aldehyde and p-t-amyl cyclohexanone), polycychc compounds (such as coumann and β-naphthyl methyl ether), esters (such as diethyl phthalate, phenylethyl phenylacetate, non-annelid- 1 4) Fragrances also mclude esters and essential oils denved from floral matenals and fruits, citrus oils, absolutes, aldehydes, resmoides, musk and other animal notes (e g , natural isolates of civet, castoreum and musk), balsamic, etc and alcohols (such as dimyrcetol, phenylethyl alcohol and tetrahydromuguol) Examples of such components useful m fragrances herem mclude decyl aldehyde, undecyl aldehyde, undecylenic aldehyde, launc aldehyde, amyl cinnamic aldehyde, ethyl methyl phenyl glycidate, methyl nonyl acetaldehyde, mynstic aldehyde, nonalactone, nonyl aldehyde, octyl aldehyde, undecalactone. hexyl cinnamic aldehyde, benzaldehyde, vanillin, hehotropine, camphor, para-hydroxy phenolbutanone, 6-acetyl 1,1,3,4,4,6 hexamethyl tetrahydronaphthalene, alpha-methyl lonone, gamma- methyl lonone, and amyl-cyclohexanone and mixtures of these components

Other suitable but optional fragrances are those which mask or help to mask odors associated with perspiration (hereinafter refened to as odor maskmg fragrances), some nonlimiting examples of which are descnbed m U S Patent 5,554,588, U S Patent 4,278,658, U S Patent 5,501,805, and EP Patent Application 684 037 Al, all of which are mcorporated herem by reference in their entirety Prefened odor maskmg fragrances are those which have a Deodorant Value of at least about 0 25, more preferably from about 0 25 to about 3 5, even more preferably from about 0 9 to about 3 5, as measured by the Deodorant Value Test descnbed m EP Patent Application 684 037 A 1

The optional fragrance may also contam solubilizers, diluents, or solvents which are well known in the art Such matenals are descnbed m Arctander, Perfume and Flavour Chemicals (Aroma Chemicals), Vol I and II (1969) These matenals typically mclude dipropylene glycol, diethylene glycol, C^-C^ alcohols (other than 1,2-hexandιol), and benzyl alcohol Optional Ingredients

The antiperspirant compositions of the present mvention may further compnse one or more optional components which may modify the physical, chemical, cosmetic or aesthetic charactenstics of the compositions or serve as additional "active" components when deposited on the skin The compositions may also further compnse optional inert mgredients Many such optional ingredients are known for use in deodorants, antiperspirants or other personal care compositions, and may also be used in the antiperspirant compositions herem, provided that such optional matenals are compatible with the essential matenals descnbed herem, or do not otherwise unduly impair product performance Nonlimiting examples of optional mgredients suitable for use m the antiperspirant compositions herein mclude pH buffering agents, additional emollients, humectants, soothing agents, dyes and pigments, medicaments, baking soda and related matenals, preservatives, and soothing agents such as aloe vera, allantom, D-panthenol, avocado oil and other vegetative oils, and lichen extract

Skin Irritation It has been found that solutions of solubilized antiperspirant active and isopropyl glycerol ether are less imtatmg to the skm than other similar compositions, mcludmg deodorant compositions containing propylene glycol and dipropylene glycol as descnbed hereinafter To emphasize this benefit, the compositions descnbed m Table 1 are evaluated for skm imtation m a three day patch test Skm imtation potential is measured by visual gradmg of skm erythema (redness) by qualified skm graders using a 0 (no apparant skm imtation) to 4 (severe skm untation) gradmg scale Data are reported as a least square mean average (LS mean score) of 21 panelists with statistics

Table 1

The data set forth in Table 1 shows that compositions containing antiperspirant active solubilized m 75%) isopropyl glycerol ether are less imtatmg (statistically significant at 90% confidence) to the skm than deodorant compositions containing at total of about 60% polyhydnc alcohols (about 20% propylene glycol and about 40% dipropylene glycol)

Method of Manufacture

The compositions of the present mvention may be made by any of the methods known in the art for formulating antiperspirant compositions, or which are otherwise effective in formulating such compositions As will be apparent to those skilled m the art, the particular method will be dependent upon the selection of the specific types and amounts of the components employed, as well as the final product form desired, e g , liquids, sticks, soft solids, creams, lotions, smgle or multiple phase systems containing solid or dissolved antiperspirant active, suspensions or solutions, clear or translucent or opaque, etc In general, the antiperspirant compositions of the present mvention can be prepared by merely combmmg the liquid earner with the antiperspirant active Optional mgredients can be added m any known or otherwise effective matter for formulating the desired product form

For example, to formulate an anhydrous composition containing solubilized antiperspirant active, the antiperspirant active may be solubilized m an aqueous earner compnsmg a polyol solvent, wherem the polyol solvent is or compnses isopropyl glycerol ether, and then processed to remove substantially all of the water m the resultmg composition Suitable processing methods for application m this manner mclude those methods descnbed m U S Patent 4,781,917 (Luebbe et al ), U S Patent 5,643,558 (Provancal et al ), and European Patent Application 0 404 533 Al (Smith et al ), which descnptions are mcorporated herem by reference To formulate a solid or soft solid stick, the liquid earner is combmed with an optional suspendmg agent The combmation is heated until it appears to be clear and homogenous, which will typically occur for most combmations at a temperature of between about 60°C and about 130°C The resulting clear liquid is cooled or allowed to cool to between about 40°C and about 120^CC at which time the solid or solubilized antiperspirant active is added to and thoroughly mixed m the clear liquid along with any other optional mgredients The resulting liquid mixture is then poured mto contamers and allowed to cool and solidify to the desired product hardness Alternatively, the antiperspirant active or other optional mgredients can be added along with the liquid earner and the optional suspendmg agent, or at any other time that is suitable for such addition m order to manufacture the desired product form

To formulate an aerosol, roll-on or other liquid formulation, any known or otherwise effective manufacturmg or formulation method can be use to formulate the antiperspirant compositions m such product forms

Nonlimiting examples of suitable methods for manufacturmg the antiperspirant compositions of the present mvention are descnbed in U S Patent 5,429,816 (Hofhchter et al ), U S Patent 5,733,534 (Sawin et al ), U S Patent 5,605,681 (Trandai et al ), U S Patent 5,346,694 (Juneja), U S Patent 5,298,236 (On et al ), and U S Patent 5,718,890 (Putnam et al ), which descnptions are mcorporated herem be reference

Method For Use

The antiperspirant composition of the present mvention may be used as an intermediate in formulating other antiperspirant compositions, or it may be formulated m final form to be topically applied to the axilla or other area of the skm m any known or otherwise effective method for controlling malodor associated with perspiration These methods compnse applying to the axilla or other area of the human skm a safe and effective amount of the antiperspirant composition of the present mvention In this context, the term "safe and effective amount" means an amount of the antiperspirant composition topically applied to the skm which is effective m inhibiting or minimizing maskmg, perspiration at the site of application while also bemg safe for human use at a reasonable nsk/benefit ratio In this context, a safe and effective amount typically ranges from about 0 1 gram per axilla to about 2 0 gram per axilla The compositions are preferably applied to the axilla or other area of the skm one or more times daily, preferably once daily

EXAMPLES

The following Examples 1-12 illustrate specific embodiments of the antiperspirant compositions of the present mvention, mcludmg methods of manufacture and use, but are not mtended to be limiting thereof Other modifications can be undertaken by the skilled artisan without departing from the spint and scope of this mvention

Each of the exemplified compositions is applied topically to the underarm m an amount effective to inhibit or prevent perspiration m humans, typically an amount which ranges from about 0 1 gram to about 2 grams per axilla The applied compositions are effective in inhibiting perspiration from the applied areas, and have good skm feel charactenstics during and after application The applied compositions are milder to the skm and cause little or no skm imtation All exemplified amounts are weight-weight percents based on the total weight of the composition, unless otherwise specified

The antiperspirant compositions descnbed m Examples 1-7 contam solubilized antiperspirant active, whereas the antiperspirant compositions descnbed m Examples 8-13 contam solid antiperspirant active

Examples 1-7

The antiperspirant compositions of the present mvention mcludes the clear or translucent liquid compositions (Examples 1-7) as descnbed below Each contains solubilized antiperspirant active and is formulated by methods well known for makmg solubilized antiperspirant active or product forms containing them These compositions may be applied topically to the skm, or they may be used as intermediates m formulating other antiperspirant product forms which contam solubilized antiperspirant active

Table 2

Example 8

The antiperspirant compositions of the present mvention mcludes the gel solid stick composition described below The gel solid stick contains solid antiperspirant active and is formulated m accordance with the methods descnbed in U S Patent 5,429,816

Example 9

The antiperspirant compositions of the present mvention mcludes the solid stick embodiment descnbed below The solid stick is formulated by methods well known for prepanng antiperspirant sticks

Example 10

The antiperspirant compositions of the present mvention mclude the roll-on embodiment descnbed below. The roll-on embodiement is formulated by methods well known for prepanng liquid or roll-on antiperspirant compositions, and is contained within a suitable roll-on package

Example 11 The antiperspirant compositions of the present mvention mcludes the aerosol embodiment descnbed below. It is formulated by methods well known for prepanng aerosolized antiperspirant compositions, and is contained within a suitable aerosolized package.

The aerosol antiperspirant composition of Example 11 is an embodiment of the present mvention which can be topically applied to the underarm and causes minimal or no skm imtation It has a dry feel dunng and after application and does not leave a sticky residue on the underarm

Example 12

The antiperspirant compositions of the present mvention mcludes the soft solid or cream embodiment descnbed below It is formulated m accordance with the methods descnbed m U S Patent U S Patent 5,718,890 (Putnam et al ), and is contamed within the perforated dome packages descnbed m the Putnam et al patent

Claims

WHAT IS CLAIMED IS:

1 An antiperspirant composition comprising A) from 0 1 % to 99 9% by weight of isopropyl glycerol ether, and

B) from 0 1 % to 99 9% by weight of an antiperspirant active

2 The antiperspirant composition of Claim 2 wherein the composition is visibly clear or translucent at 25°C

3 The antiperspirant composition of any one of the preceding claims wherein the composition comprises from 1 % to 40% by weight of the isopropyl glycerol ether

4 The antiperspirant composition of any one of the preceding claims wherein the composition further comprises from 1 % to 35% by weight of a dimethiconol

5 The antiperspirant composition of any one of the preceding claims wherein the composition further comprises 10% to 90% by weight of a volatile silicone carrier liquid

6 The antiperspirant composition of any one of the preceding claims wherein the composition further comprises from 0 1 % to 35% by weight of a suspending or thickening agent

7 The antiperspirant composition of any one of the preceding claims wherein the antiperspirant active is solubilized and represents from 0 5% to 25% by weight of the composition

8 The antiperspirant composition of any one of the preceding claims, wherein the composition is anhydrous and contains less than 3% by weight of free or added water

9 The antiperspirant composition of any one of the preceding claims wherein the antiperspirant active is selected from the group consisting of aluminum salts, zirconium salts, and combinations thereof

10 A method of controlling malodor associated with perspiration comprising the topical application to the axillary area of an effective amount of the antiperspirant composition of any one of the preceding claims