WO2001013949A3 - Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen - Google Patents

Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen Download PDF

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Publication number
WO2001013949A3
WO2001013949A3 PCT/DE2000/002720 DE0002720W WO0113949A3 WO 2001013949 A3 WO2001013949 A3 WO 2001013949A3 DE 0002720 W DE0002720 W DE 0002720W WO 0113949 A3 WO0113949 A3 WO 0113949A3
Authority
WO
WIPO (PCT)
Prior art keywords
arthritis
joint diseases
medical preparation
groups
shelled
Prior art date
Application number
PCT/DE2000/002720
Other languages
English (en)
French (fr)
Other versions
WO2001013949A2 (de
Inventor
Andreas Jordan
Original Assignee
Magforce Applic Gmbh
Andreas Jordan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Magforce Applic Gmbh, Andreas Jordan filed Critical Magforce Applic Gmbh
Priority to AT00967511T priority Critical patent/ATE302612T1/de
Priority to US10/048,037 priority patent/US6669623B1/en
Priority to DE50011033T priority patent/DE50011033D1/de
Priority to JP2001518085A priority patent/JP2003507434A/ja
Priority to AU77695/00A priority patent/AU7769500A/en
Priority to EP00967511A priority patent/EP1204426B1/de
Publication of WO2001013949A2 publication Critical patent/WO2001013949A2/de
Publication of WO2001013949A3 publication Critical patent/WO2001013949A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1217—Dispersions, suspensions, colloids, emulsions, e.g. perfluorinated emulsion, sols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Ein medizinisches Präparat zur Behandlung von Arthrose, Arthritis und rheumatischen Erkrankungen umfaßt eine Suspension aus ein- oder mehrschaligen nanoskaligen Teilchen, die jeweils aus einem eisenoxidhaltigen Kern und einer inneren Schale mit zur Bildung von kationischen Gruppen befähigten Gruppen bzw. Wahlweise mindestens einer äußeren Schale mit neutralen und/oder anionischen Gruppen bestehen. An die innere Schale sind Radionuklide und unter Wärmeeinfluß zytotoxisch wirkende Stoffe gebunden. Das in den Gelenkspalt injizierte und einem magnetischen Wechselfeld ausgesetzte Präparat verspricht aufgrund der hohen Phagozytoserate und der trimodalen kombinatorischen Wirkung von Thermo-, Radio- und Chemotherapie einen hervorragenden Therapieerfolg.
PCT/DE2000/002720 1999-08-19 2000-08-09 Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen WO2001013949A2 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AT00967511T ATE302612T1 (de) 1999-08-19 2000-08-09 Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen
US10/048,037 US6669623B1 (en) 1999-08-19 2000-08-09 Medical preparation for treating arthrosis, arthritis and other rheumatic joint diseases
DE50011033T DE50011033D1 (de) 1999-08-19 2000-08-09 Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen
JP2001518085A JP2003507434A (ja) 1999-08-19 2000-08-09 関節症、関節炎、及び他のリウマチ性関節疾患を治療するための医療用調製物
AU77695/00A AU7769500A (en) 1999-08-19 2000-08-09 Medical preparation for treating arthrosis, arthritis and other rheumatic joint diseases
EP00967511A EP1204426B1 (de) 1999-08-19 2000-08-09 Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19940220.5 1999-08-19
DE19940220A DE19940220B4 (de) 1999-08-19 1999-08-19 Medizinisches Präparat zur Behandlung von Arthrose, Arthritis und anderen rheumatischen Gelenkerkrankungen

Publications (2)

Publication Number Publication Date
WO2001013949A2 WO2001013949A2 (de) 2001-03-01
WO2001013949A3 true WO2001013949A3 (de) 2001-12-20

Family

ID=7919494

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2000/002720 WO2001013949A2 (de) 1999-08-19 2000-08-09 Medizinisches präparat zur behandlung von arthrose, arthritis und anderen rheumatischen gelenkerkrankungen

Country Status (8)

Country Link
US (1) US6669623B1 (de)
EP (1) EP1204426B1 (de)
JP (1) JP2003507434A (de)
AT (1) ATE302612T1 (de)
AU (1) AU7769500A (de)
DE (2) DE19940220B4 (de)
ES (1) ES2249297T3 (de)
WO (1) WO2001013949A2 (de)

Families Citing this family (13)

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Publication number Priority date Publication date Assignee Title
US7951061B2 (en) * 2001-07-25 2011-05-31 Allan Foreman Devices for targeted delivery of thermotherapy, and methods related thereto
US7731648B2 (en) * 2001-07-25 2010-06-08 Aduro Biotech Magnetic nanoscale particle compositions, and therapeutic methods related thereto
WO2003022308A2 (en) * 2001-09-13 2003-03-20 Scientific Generics Limited Therapeutic insert and therapeutic method
WO2004000916A2 (en) * 2002-02-04 2003-12-31 Nanophase Technologies Corporation Stable dispersions of nanoparticles in aqueous media
DE102005039579B4 (de) * 2005-08-19 2022-06-30 Magforce Ag Verfahren zur Einschleusung von therapeutischen Substanzen in Zellen
US20080281386A1 (en) * 2007-05-09 2008-11-13 Tessaron Medical, Inc. Systems and methods for treating body tissue
US20080281318A1 (en) * 2007-05-09 2008-11-13 Tessaron Medical, Inc. Systems and methods for inductive heat treatment of body tissue
US20090157069A1 (en) * 2007-12-06 2009-06-18 Curtis Tom Systems and methods for thermal treatment of body tissue
DE102009058650A1 (de) 2009-12-16 2011-06-22 Leibniz-Institut für Neue Materialien gemeinnützige GmbH, 66123 Magnetische Kompositpartikel
EP2558108A1 (de) * 2010-04-12 2013-02-20 Ramot at Tel-Aviv University Ltd Eisenoxidnanopartikel zur verwendung bei der behandlung von nicht infektiösen entzündungserkrankungen
KR101985981B1 (ko) 2011-03-10 2019-06-04 매그포스 아게 열치료를 계획하는데 도움을 주기 위한 컴퓨터 보조 시뮬레이션 도구
RU2622025C2 (ru) 2011-08-10 2017-06-08 Магфорс Аг Агломерирование магнитных покрытых алкоксисиланом наночастиц
DE102012213839B4 (de) * 2012-08-03 2017-06-14 Leibniz-Institut Für Festkörper- Und Werkstoffforschung Dresden E.V. Verfahren zur kontrollierten Bewegung von Objekten in flüssigen Medien

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758429A (en) * 1985-11-04 1988-07-19 Gordon Robert T Method for the treatment of arthritis and inflammatory joint diseases
US5149319A (en) * 1990-09-11 1992-09-22 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids
DE19726282A1 (de) * 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4303636A (en) * 1974-08-20 1981-12-01 Gordon Robert T Cancer treatment
US4590922A (en) * 1983-08-19 1986-05-27 Gordon Robert T Use of ferromagnetic, paramagnetic and diamagnetic particles in the treatment of infectious diseases
US5655546A (en) * 1995-06-07 1997-08-12 Halpern; Alan A. Method for cartilage repair
DE19716732C2 (de) * 1997-03-07 1999-03-25 Max Delbrueck Centrum Spezifische Magnetosomen, Verfahren zu ihrer Herstellung und ihre Verwendung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758429A (en) * 1985-11-04 1988-07-19 Gordon Robert T Method for the treatment of arthritis and inflammatory joint diseases
US5149319A (en) * 1990-09-11 1992-09-22 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids
DE19726282A1 (de) * 1997-06-20 1998-12-24 Inst Neue Mat Gemein Gmbh Nanoskalige Teilchen mit einem von mindestens zwei Schalen umgebenen eisenoxid-haltigen Kern

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; MASAI, AKIRA: "Development of Anticancer-Agent-Releasing Microcapsules for Chemotherapy Combined with Embolo- Hyperthermic Therapy.", XP002174710, retrieved from STN Database accession no. PREV199598223481 *
GRADY E.D. ET AL: "Combination of internal radiation therapy and hyperthermia to treat liver cancer.", SOUTHERN MEDICAL JOURNAL, (1983) 76/9 (1101-1105). CODEN: SMJOAV, XP001015654 *
NIPPON ACTA RADIOLOGICA, (1995) VOL. 55, NO. 1, PP. 50-57. *

Also Published As

Publication number Publication date
ATE302612T1 (de) 2005-09-15
WO2001013949A2 (de) 2001-03-01
DE19940220A1 (de) 2001-02-22
EP1204426B1 (de) 2005-08-24
ES2249297T3 (es) 2006-04-01
JP2003507434A (ja) 2003-02-25
AU7769500A (en) 2001-03-19
US6669623B1 (en) 2003-12-30
DE50011033D1 (de) 2005-09-29
EP1204426A2 (de) 2002-05-15
DE19940220B4 (de) 2007-05-03

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