WO2001028961A3 - Method for the direct esterification of sorbitol with fatty acids - Google Patents

Method for the direct esterification of sorbitol with fatty acids Download PDF

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Publication number
WO2001028961A3
WO2001028961A3 PCT/US2000/028419 US0028419W WO0128961A3 WO 2001028961 A3 WO2001028961 A3 WO 2001028961A3 US 0028419 W US0028419 W US 0028419W WO 0128961 A3 WO0128961 A3 WO 0128961A3
Authority
WO
WIPO (PCT)
Prior art keywords
sorbitol
direct esterification
esterification
fatty acids
need
Prior art date
Application number
PCT/US2000/028419
Other languages
French (fr)
Other versions
WO2001028961A2 (en
Inventor
Michael T Weusthoff
Julian Stowell
Paul Mcgrane
Gordon Greutzmacher
George W Borden
Gary J Flynn
Joe W Johnson
James M Anderson
John Teixeira
James W Miller
Russell J Hausman
Ping W Chang
Original Assignee
Danisco Cultor America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Cultor America Inc filed Critical Danisco Cultor America Inc
Priority to CA002388296A priority Critical patent/CA2388296A1/en
Priority to EP00970894A priority patent/EP1235818A4/en
Priority to AU80210/00A priority patent/AU8021000A/en
Priority to JP2001531767A priority patent/JP2003512343A/en
Publication of WO2001028961A2 publication Critical patent/WO2001028961A2/en
Publication of WO2001028961A3 publication Critical patent/WO2001028961A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Abstract

Mixtures of sorbitol fatty acid esters useful as low calorie fat substitutes are prepared through a direct esterification process. The process entails the direct esterification of sorbitol with free fatty acids, optionally in the presence of an esterification catalyst. The resulting sorbitol esters have an average degree of hydroxyl substitution ranging from about 3 to about 5.5. This partial esterification leads to a mixture of esters capable of serving as low calorie fat substitutes without undesirable physiological side effects or the need for additives. Furthermore, the direct esterification process proceeds without the need for large amounts of organic solvents of bleaching agents.
PCT/US2000/028419 1999-10-15 2000-10-13 Method for the direct esterification of sorbitol with fatty acids WO2001028961A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002388296A CA2388296A1 (en) 1999-10-15 2000-10-13 Method for the direct esterification of sorbitol with fatty acids
EP00970894A EP1235818A4 (en) 1999-10-15 2000-10-13 Method for the direct esterification of sorbitol with fatty acids
AU80210/00A AU8021000A (en) 1999-10-15 2000-10-13 Method for the direct esterification of sorbitol with fatty acids
JP2001531767A JP2003512343A (en) 1999-10-15 2000-10-13 Method for direct esterification of sorbitol with fatty acids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15956399P 1999-10-15 1999-10-15
US60/159,563 1999-10-15

Publications (2)

Publication Number Publication Date
WO2001028961A2 WO2001028961A2 (en) 2001-04-26
WO2001028961A3 true WO2001028961A3 (en) 2001-12-06

Family

ID=22573081

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/028419 WO2001028961A2 (en) 1999-10-15 2000-10-13 Method for the direct esterification of sorbitol with fatty acids

Country Status (7)

Country Link
US (1) US7151186B2 (en)
EP (1) EP1235818A4 (en)
JP (1) JP2003512343A (en)
CN (1) CN1183124C (en)
AU (1) AU8021000A (en)
CA (1) CA2388296A1 (en)
WO (1) WO2001028961A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002303357A1 (en) * 2001-05-17 2002-11-25 Exxonmobil Chemical Patents, Inc. Biodegradable synthetic lubricants
US8815282B1 (en) * 2005-07-15 2014-08-26 Edward C. Leonard Commercial method for production of room temperature-liquid cetyl myristoleate
CN100443460C (en) * 2005-12-27 2008-12-17 中国石油化工股份有限公司 Process for preparing carboxylic acid ester
US20080057552A1 (en) * 2006-08-31 2008-03-06 Inmok Lee Processes for Producing Fats or Oils and Compositions Comprising the Fats or Oils
US9282737B2 (en) 2008-02-08 2016-03-15 Nof Corporation Agent for preventing pollen dispersal
JP4715926B2 (en) * 2009-01-14 2011-07-06 カシオ計算機株式会社 Radio wave receiver
US20110217204A1 (en) * 2010-03-05 2011-09-08 Franciskovich Phillip P Sterilization composition
AU2016279798B2 (en) * 2015-06-15 2021-07-08 Qaam Pharmaceuticals, Llc Glycopyrronium fatty acid salts and methods of making same
CN109734584A (en) * 2018-11-02 2019-05-10 佛山市银美联合科技有限公司 A kind of synthetic method of trimethylolpropane tris caprylate/tri- decylates
CN115772080B (en) * 2022-12-08 2023-07-14 哈尔滨理工大学 Preparation method and application of acrylic acid modified sorbitol water tree inhibitor

Family Cites Families (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL158165B (en) * 1973-05-15 1978-10-16 Amsterdam Chem Comb PROCESS FOR THE PREPARATION OF CARBONIC ACID ESTERS FROM LINEAR ALIPHATIC SUGAR ALCOHOLS.
US4334061A (en) 1979-10-29 1982-06-08 Ethyl Corporation Process for recovery of polyol fatty acid polyesters
US4382924A (en) 1980-06-25 1983-05-10 The Procter & Gamble Company Palatable composition containing oil or oil-like materials
CA1185610A (en) 1981-06-22 1985-04-16 Paul Seiden Polyglycerol ester synthesis
US4368213A (en) 1981-06-23 1983-01-11 The Procter & Gamble Company Emulsion concentrate for palatable polyester beverage
US4461782A (en) 1982-02-16 1984-07-24 The Procter & Gamble Company Low calorie baked products
DE3240892A1 (en) * 1982-11-05 1984-05-10 Hoechst Ag, 6230 Frankfurt METHOD FOR PRODUCING CARBONIC ACID ESTERS FROM HEXITES
US4517360A (en) 1983-06-23 1985-05-14 The Procter & Gamble Company Synthesis of higher polyol fatty acid polyesters using carbonate catalysts
US4518772A (en) 1983-06-23 1985-05-21 The Proctor & Gamble Company Synthesis of higher polyol fatty acid polyesters using high soap:polyol ratios
JPS60227687A (en) * 1984-04-25 1985-11-12 Dai Ichi Kogyo Seiyaku Co Ltd Production of sugar alcohol fatty acid esters
JPS6115893A (en) 1984-06-29 1986-01-23 Dai Ichi Kogyo Seiyaku Co Ltd Purification of sucrose fatty acid ester
US4705691A (en) 1985-11-18 1987-11-10 The Procter & Gamble Co. Beverage opacifier
US4705690A (en) 1985-11-18 1987-11-10 The Procter & Gamble Co. Weighting oil substitutes
JPH0641439B2 (en) * 1985-12-27 1994-06-01 日本油脂株式会社 Process for producing polyoxyalkylene polyhydric alcohol oleate
EP0235836B1 (en) 1986-02-19 1989-11-29 Unilever N.V. Fatty acid esters of sugars and sugar alcohols
US5158796A (en) 1986-02-20 1992-10-27 The Procter & Gamble Company Polyol fatty acid polyester compositions with improved taste
EP0236288B1 (en) 1986-02-20 1993-12-15 The Procter & Gamble Company Low calorie fat materials that eliminate laxative side effect
EP0233856B1 (en) 1986-02-20 1994-01-05 The Procter & Gamble Company Better tasting low calorie fat materials
US4942228A (en) 1986-05-06 1990-07-17 The Procter & Gamble Company Production of polyol polyesters having reduced color content
NL8601904A (en) 1986-07-23 1988-02-16 Unilever Nv PROCESS FOR THE PREPARATION OF POLYOL FATTY ACID POLYESTERS.
US4822875A (en) 1986-12-17 1989-04-18 The Procter & Gamble Company Sucrose polyesters which behave like cocoa butters
US4789664A (en) 1986-12-19 1988-12-06 The Procter & Gamble Company Food compositions with superior blood cholesterol lowering properties
ATE91592T1 (en) 1986-12-19 1993-08-15 Procter & Gamble NUTRITIONAL COMPOSITION WITH HIGHER BLOOD CHOLESTEROL LOWERING PROPERTIES.
US4806632A (en) 1986-12-29 1989-02-21 The Procter & Gamble Company Process for the post-hydrogenation of sucrose polyesters
US4810516A (en) 1987-02-27 1989-03-07 The Procter & Gamble Company Reduced calorie and reduced fat chocolate confectionery compositions
US5017398A (en) 1987-04-10 1991-05-21 The Procter & Gamble Company Improved margarine compositions/containing solid sucrose polyesters
US4797300A (en) 1987-04-10 1989-01-10 The Procter & Gamble Company Compositions containing novel solid, nondigestible, fat-like compounds
US5147675A (en) 1987-04-15 1992-09-15 The Procter & Gamble Company Process for making extrusion cooked snack chips
US4880657A (en) 1987-05-06 1989-11-14 The Procter & Gamble Company Shortening compositions containing polyol polyesters
US4940601A (en) 1987-05-06 1990-07-10 The Procter & Gamble Company Sucrose fatty acid ester compositions and shortenings and margarines made therefrom
US4962092A (en) 1987-05-06 1990-10-09 The Procter & Gamble Company Compositions for treating duodenal ulcers
US4960602A (en) 1987-05-06 1990-10-02 The Procter & Gamble Company Food or beverage compositions with altered flavored display
US5021256A (en) 1987-05-06 1991-06-04 The Procter & Gamble Company Shortening compositions containing polyol polyesters
US4968791A (en) 1987-07-23 1990-11-06 Lever Brothers Company Process for the preparation of polyol fatty acid esters
DE3862629D1 (en) 1987-08-19 1991-06-06 Unilever Nv EDIBLE FAT-COMPOSITION AND METHOD FOR THE PRODUCTION THEREOF.
US5248509A (en) 1987-08-19 1993-09-28 Van Den Bergh Foods Co., Food product containing oil-soluble vitamins, digestible fat and indigestible polyol fatty acid polyesters
US4835001A (en) 1987-09-09 1989-05-30 The Proctor & Gamble Company Baked goods made with sucrose fatty acid esters
GB8728385D0 (en) 1987-12-04 1988-01-13 Unilever Plc Method of purifying crude polyol fatty acid polyester products
DE3889084T2 (en) 1987-12-11 1994-08-11 Unilever Nv Process for the preparation of polyol fatty acid esters.
GB8730266D0 (en) 1987-12-29 1988-02-03 Unilever Plc Process for synthesis of polyol fatty acid polyesters
GB8800087D0 (en) 1988-01-05 1988-02-10 Unilever Plc Process for synthesis of polyol fatty acid polyesters
US4954621A (en) 1988-06-14 1990-09-04 Mitsubushi Kasei Corporation Process for producing sucrose fatty acid polyester
US4877871A (en) 1988-06-14 1989-10-31 Nabisco Brands, Inc. Synthesis of sucrose polyester
GB8815224D0 (en) 1988-06-27 1988-08-03 Unilever Plc Bakery-margarine composition
US5006360B1 (en) 1988-06-27 1992-04-28 Low calorie fat substitute compositions resistant to laxative side effect
US5231199B1 (en) 1988-06-29 1998-08-04 Bergh Foods Co Process for the synthesis of polyol fatty acid polyesters
US4931552A (en) 1988-06-30 1990-06-05 The Procter & Gamble Company Production of polyol polyesters having reduced color content
US4883684A (en) 1988-07-01 1989-11-28 The Procter & Gamble Company Functional hardstock fat composition
JPH0762025B2 (en) 1988-10-05 1995-07-05 昭和産業株式会社 Method for stabilizing polyol fatty acid polyester
CA2006132A1 (en) 1988-12-21 1990-06-21 Bernardus C. J. De Boer Low-calorie food products
US5102683A (en) 1988-12-22 1992-04-07 The Procter & Gamble Company Fatty compositions with high solids content
US4919964A (en) 1988-12-22 1990-04-24 The Procter & Gamble Company Shelf stable, highly aerated reduced calorie food products
DK0383375T3 (en) 1989-02-13 1993-08-02 Unilever Plc Cheese product and process for making them
US5043438B1 (en) 1989-02-16 1998-04-28 Lever Brothers Ltd Process for the synthesis of polyol fatty-acid esters
US5419925A (en) 1989-03-28 1995-05-30 The Procter & Gamble Company Reduced calorie fat compositions containing polyol polyesters and reduced calorie triglycerides
CA2012381C (en) 1989-03-28 1997-07-01 Paul Seiden Reduced calorie fat compositions containing polyol polyesters and reduced calorie triglycerides
US5061503A (en) 1989-06-14 1991-10-29 The Procter & Gamble Company Simulated cheese products with reduced animal fat and calories
CA2017461C (en) 1989-06-14 1997-03-11 Josephine Ling Yee Kong-Chan Simulated cheese analogs with reduced animal fat and calories
CA2027418C (en) 1989-10-16 1997-12-09 Robert Houston Polyol polyester synthesis
US5194281A (en) 1989-10-16 1993-03-16 The Procter & Gamble Company Polyol fatty acid polyesters with reduced trans double bond levels and process for making
EP0434117B1 (en) 1989-12-21 1996-10-02 Unilever N.V. Process for refining soapcontaining crude polyol fatty-acid polyester reaction products
ATE120754T1 (en) 1989-12-21 1995-04-15 Unilever Nv METHOD FOR REFINING RAW PRODUCTS CONTAINING SOAP FROM A POLYOL-FATTY ACID ESTERIFICATION MIXTURE.
ATE120755T1 (en) 1989-12-21 1995-04-15 Unilever Nv METHOD FOR REFINING ORGANIC SOLVENT-CONTAINING RAW PRODUCTS FROM A POLYOL-FATTY ACID-ESTERIFICATION MIXTURE.
US5084295A (en) 1990-02-02 1992-01-28 The Procter & Gamble Company Process for making low calorie fat-containing frozen dessert products having smooth, creamy, nongritty mouthfeel
US5306516A (en) 1990-04-26 1994-04-26 The Procter & Gamble Company Shortening compositions containing polyol fatty acid polyesters
US5306515A (en) 1990-04-26 1994-04-26 The Procter & Gamble Company Reduced calorie pourable shortening, cooking oils, salad oils or like compositions
ES2069289T3 (en) 1990-04-26 1995-05-01 Procter & Gamble FOODS WITH A FAT CONTEXT OF LOW MOISTURE SUCH AS PIECES OF ENGLISH POTATOES THAT HAVE LESS WAX CHARACTER AND IMPROVED FLAVOR DISPLAY.
US5306514A (en) 1990-04-26 1994-04-26 The Procter & Gamble Company Solid, nondigestible, fat-like compounds and food compositions containing same
US5085884A (en) 1990-04-26 1992-02-04 The Procter & Gamble Company Reduced calorie potato chips and other low moisture fat-containing foods having less waxiness and improved flavor display
ATE147587T1 (en) 1990-07-20 1997-02-15 Unilever Nv EDIBLE COMPOSITION CONTAINING FAT
US5124301A (en) 1990-09-04 1992-06-23 The Procter & Gamble Company Highly alkaline transesterification catalyst, e.g., alkali metal alkoxide, protected by fatty acid esters
US5130151A (en) 1990-12-26 1992-07-14 Megafoods, Inc. Natural and synthetic edible moisture barrier
US5366753A (en) 1991-03-29 1994-11-22 Curtice-Burns, Inc. Fat substitute compositions having reduced laxative effects at low levels of inclusion
WO1992018591A2 (en) 1991-04-12 1992-10-29 The Procter & Gamble Company Process for improving oxidative stability of polyol fatty acid polyesters
US5314707A (en) 1991-05-24 1994-05-24 The Procter & Gamble Company Polyol fatty acid polyester cooking mediums
ES2102506T3 (en) * 1991-06-25 1997-08-01 Cultor Oy FAT SUBSTITUTE LOW IN CALORIES.
EP0602156B1 (en) 1991-09-03 1996-08-14 The Procter & Gamble Company Use of hydrophobic silica to control or prevent passive oil loss
WO1993011141A1 (en) 1991-11-29 1993-06-10 Unilever N.V. Process for the synthesis of polyol fatty acid polyesters
US5308640A (en) 1992-08-28 1994-05-03 The Procter & Gamble Company Low greasiness french fries and methods for preparing same
SG79904A1 (en) 1992-10-30 2001-04-17 Procter & Gamble Nondigestible fat compositions containing cocrystallized blend of polyol polyester hardstock and crystal modifier as a passive oil loss control agent
ES2160107T3 (en) 1992-10-30 2001-11-01 Procter & Gamble COMPOSITIONS OF NON-DIGERABLE FATS CONTAINING POLYESTERS OF DIFFERENTLY STERIFIED POLYOLS FOR THE CONTROL OF PASSIVE OIL LOSS.
CA2145994C (en) 1992-10-30 1999-02-16 Patrick Joseph Corrigan Nondigestible fat compositions containing solid polyol polyester polymer for passive oil loss control
US5422131A (en) 1992-10-30 1995-06-06 The Procter & Gamble Company Nondigestible fat compositions containing relatively small nondigestible solid particles for passive oil loss control
US5440027A (en) 1993-10-05 1995-08-08 Kraft General Foods, Inc. Method for preparing saccharide fatty acid polyesters by transesterification
US5378478A (en) 1993-12-30 1995-01-03 Kraft General Foods, Inc. Manufacture of cheese products with polyol polyester fat substitutes
US5486372A (en) 1994-03-08 1996-01-23 Kraft Foods, Inc. Frozen dairy product containing polyol polyesters
US5504202A (en) 1994-04-05 1996-04-02 Henkel Corporation Sucrose polyester useful as fat subtitute and preparation process
US5491226A (en) 1994-04-06 1996-02-13 Procter & Gamble Company Process for preparing polyol polyesters having low levels of triglycerides
US5472728A (en) 1994-04-22 1995-12-05 Kraft Foods, Inc. Edible fat-containing margarine type products and process for preparing same
WO1995030337A1 (en) 1994-05-06 1995-11-16 Kraft Foods, Inc. Method of making reduced calorie peanut products
US5474795A (en) 1994-08-19 1995-12-12 Kraft Foods, Inc. Dextrose-containing chocolate products with sucrose fatty acid polyester fat substitutes
US5518754A (en) 1994-08-19 1996-05-21 Kraft Foods, Inc. Chocolate products with sucrose fatty acid polyester fat substitutes
JPH0881414A (en) * 1994-09-12 1996-03-26 Lion Corp Production of polyol ester of fatty acid
US5587196A (en) 1995-02-15 1996-12-24 Kraft Foods, Inc. Methods and compositions to add flavor to food products containing lipid
US5681948A (en) 1995-03-06 1997-10-28 Kraft Foods, Inc. Two-stage method for preparing polyol fatty acid polyesters
US5596085A (en) 1995-04-11 1997-01-21 Kraft Foods, Inc. Method for preparing polyol fatty acid polyesters by transesterification
US5532019A (en) 1995-06-05 1996-07-02 Kraft Foods, Inc. Process for making stable emulsified dressings with polyol fatty acid polyesters
US5648483A (en) 1995-06-07 1997-07-15 The Procter & Gamble Company Continuous transesterification method for preparing polyol polyesters
US5767257A (en) 1996-07-19 1998-06-16 The Procter & Gamble Company Methods for producing polyol fatty acid polyesters using atmospheric or superatmospheric pressure

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BRANDNER ET AL.: "Drying oils from sorbitol and linseed fatty acids", INDUSTRIAL AND ENGINEERING CHEMISTRY, vol. 37, no. 9, September 1945 (1945-09-01), pages 809 - 812, XP002939340 *

Also Published As

Publication number Publication date
CA2388296A1 (en) 2001-04-26
US7151186B2 (en) 2006-12-19
CN1420877A (en) 2003-05-28
AU8021000A (en) 2001-04-30
CN1183124C (en) 2005-01-05
WO2001028961A2 (en) 2001-04-26
JP2003512343A (en) 2003-04-02
EP1235818A4 (en) 2005-01-19
EP1235818A2 (en) 2002-09-04
US20020102340A1 (en) 2002-08-01

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