WO2001030408A3 - Adhesive composition over a bioactive polymerization initiator - Google Patents

Adhesive composition over a bioactive polymerization initiator Download PDF

Info

Publication number
WO2001030408A3
WO2001030408A3 PCT/US2000/041638 US0041638W WO0130408A3 WO 2001030408 A3 WO2001030408 A3 WO 2001030408A3 US 0041638 W US0041638 W US 0041638W WO 0130408 A3 WO0130408 A3 WO 0130408A3
Authority
WO
WIPO (PCT)
Prior art keywords
bioactive
adhesive composition
polymerization initiator
composition over
polymerization
Prior art date
Application number
PCT/US2000/041638
Other languages
French (fr)
Other versions
WO2001030408A2 (en
Inventor
Upvan Narang
Daniel L Hedgpeth
Gabriel N Szabo
Ibraheem T Badejo
Joe B Barefoot
Original Assignee
Closure Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Closure Medical Corp filed Critical Closure Medical Corp
Priority to AU36375/01A priority Critical patent/AU3637501A/en
Publication of WO2001030408A2 publication Critical patent/WO2001030408A2/en
Publication of WO2001030408A3 publication Critical patent/WO2001030408A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/442—Colorants, dyes

Abstract

A composition comprising a polymerizable adhesive monomer is applied over a biologically active initiator or accelerator for polymerization of the monomer. The biologically active initiator or accelerator is a medicament that provides a desired medical or therapeutic activity as well as enhancing polymerization of the adhesive.
PCT/US2000/041638 1999-10-29 2000-10-27 Adhesive composition over a bioactive polymerization initiator WO2001030408A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU36375/01A AU3637501A (en) 1999-10-29 2000-10-27 Method of applying an adhesive composition over a bioactive polymerization initiator or accelerator

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/430,176 US6455064B1 (en) 1998-04-30 1999-10-29 Method of applying an adhesive composition over a bioactive polymerization initiator or accelerator
US09/430,176 1999-10-29

Publications (2)

Publication Number Publication Date
WO2001030408A2 WO2001030408A2 (en) 2001-05-03
WO2001030408A3 true WO2001030408A3 (en) 2002-01-10

Family

ID=23706378

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/041638 WO2001030408A2 (en) 1999-10-29 2000-10-27 Adhesive composition over a bioactive polymerization initiator

Country Status (3)

Country Link
US (1) US6455064B1 (en)
AU (1) AU3637501A (en)
WO (1) WO2001030408A2 (en)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050196431A1 (en) * 1998-04-30 2005-09-08 Upvan Narang Adhesive applicator tip with a polymerization initiator, polymerization rate modifier, and/or bioactive material
US6512023B1 (en) * 1998-06-18 2003-01-28 Closure Medical Corporation Stabilized monomer adhesive compositions
US20020110672A1 (en) * 2001-02-12 2002-08-15 Joanne Muratore-Pallatino Cosmetic skin tattoo
US6811341B2 (en) 2001-08-16 2004-11-02 Closure Medical Corporation Multiple-component combining
FR2838334B1 (en) * 2002-04-16 2006-05-26 Polymerexpert Sa NON-TOXIC RADICAL POLYMERIZATION ACTIVATOR FOR BONE OR DENTAL CEMENT
CA2457248C (en) 2003-02-07 2012-07-17 Closure Medical Corporation Applicators, dispensers and methods for dispensing and applying adhesive material
US20040223946A1 (en) * 2003-05-05 2004-11-11 Closure Medical Corporation Adhesive treatment for insect and related bites
US20040223932A1 (en) * 2003-05-05 2004-11-11 Closure Medical Corporation Adhesive treatment for acne
US20050042266A1 (en) * 2003-08-21 2005-02-24 Closure Medical Corporation Cyanoacrylate compositions containing anti-microbial agent
US20050047845A1 (en) * 2003-08-29 2005-03-03 Onami, Llc Self-contained system and method for substance application
US20050182443A1 (en) 2004-02-18 2005-08-18 Closure Medical Corporation Adhesive-containing wound closure device and method
US8052669B2 (en) 2004-02-25 2011-11-08 Femasys Inc. Methods and devices for delivery of compositions to conduits
US9238127B2 (en) 2004-02-25 2016-01-19 Femasys Inc. Methods and devices for delivering to conduit
US8048086B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
US8048101B2 (en) 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
RU2257200C1 (en) * 2004-05-12 2005-07-27 Кутушов Михаил Владимирович Medicinal agent
US20060009099A1 (en) 2004-07-12 2006-01-12 Closure Medical Corporation Adhesive-containing wound closure device and method
JP2006111634A (en) * 2004-10-13 2006-04-27 L'oreal Sa Composition for treating keratin material based on electrophilic monomer and salt
US20060078522A1 (en) * 2004-10-13 2006-04-13 Gabin Vic Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt
KR20060053286A (en) * 2004-10-13 2006-05-19 로레알 Use for the cosmetic treatment of keratin materials of non-tacky compositions based on electrophilic monomers and non-silicone polymers
US20060093572A1 (en) * 2004-11-03 2006-05-04 Bordoloi Binoy K Cyanoacrylate monomer formulation containing diiodomethyl-p-tolylsulfone and 2,4,4'-trichloro-2' -hydroxydiphenyl ether
US7238828B2 (en) * 2005-03-24 2007-07-03 Ethicon, Inc. Absorbable α-cyanoacrylate compositions
JP5567270B2 (en) * 2005-08-17 2014-08-06 ロチャル インダストリーズ エルエルピー Liquid coating materials and kits
US20070078207A1 (en) * 2005-09-30 2007-04-05 Jonn Jerry Y Stabilizer cyanoacrylate formulations
US20080003196A1 (en) * 2006-06-30 2008-01-03 Jonn Jerry Y Absorbable cyanoacrylate compositions
US8603138B2 (en) 2006-10-04 2013-12-10 Ethicon Endo-Surgery, Inc. Use of an adhesive to treat intraluminal bleeding
US7914511B2 (en) 2006-10-18 2011-03-29 Ethicon Endo-Surgery, Inc. Use of biosurgical adhesive as bulking agent
US7441973B2 (en) 2006-10-20 2008-10-28 Ethicon Endo-Surgery, Inc. Adhesive applicator
US7749235B2 (en) 2006-10-20 2010-07-06 Ethicon Endo-Surgery, Inc. Stomach invagination method and apparatus
US7658305B2 (en) 2006-10-25 2010-02-09 Ethicon Endo-Surgery, Inc. Adhesive applier with articulating tip
US7892250B2 (en) 2006-11-01 2011-02-22 Ethicon Endo-Surgery, Inc. Use of biosurgical adhesive on inflatable device for gastric restriction
US8876844B2 (en) 2006-11-01 2014-11-04 Ethicon Endo-Surgery, Inc. Anastomosis reinforcement using biosurgical adhesive and device
US7727175B2 (en) * 2006-11-08 2010-06-01 Ethicon Endo-Surgery, Inc. Disk bandage dispenser
US7833216B2 (en) 2006-11-08 2010-11-16 Ethicon Endo-Surgery, Inc. Fluid plunger adhesive dispenser
US7914552B2 (en) * 2006-11-09 2011-03-29 Ethicon Endo-Surgery, Inc. Method of performing an end-to-end anastomosis using a stent and an adhesive
US7721930B2 (en) * 2006-11-10 2010-05-25 Thicon Endo-Surgery, Inc. Disposable cartridge with adhesive for use with a stapling device
US7753936B2 (en) * 2006-11-10 2010-07-13 Ehticon Endo-Surgery, Inc. Form in place fasteners
US20080241249A1 (en) * 2007-03-30 2008-10-02 Closure Medical Corporation Cyanoacrylate composite
US20090320856A1 (en) * 2008-06-30 2009-12-31 John Brewer Sealant Applicator and Method
US10070888B2 (en) 2008-10-03 2018-09-11 Femasys, Inc. Methods and devices for sonographic imaging
US9554826B2 (en) 2008-10-03 2017-01-31 Femasys, Inc. Contrast agent injection system for sonographic imaging
GB2465610A (en) * 2008-11-25 2010-05-26 Ethicon Inc Medical adhesive composition comprising a alpha-cyanoacrylate monomer and a NSAID
US8608642B2 (en) 2010-02-25 2013-12-17 Ethicon Endo-Surgery, Inc. Methods and devices for treating morbid obesity using hydrogel
US8932623B2 (en) 2011-08-25 2015-01-13 Ethicon, Inc. Protective wound dressing device for oral and pharyngeal space
WO2013148722A1 (en) * 2012-03-26 2013-10-03 The Regents Of The University Of California Control of living radical polymerization by light
EP3086785A4 (en) * 2014-01-01 2017-08-30 Real Time Imaging Technologies, LLC Improved local anesthetic solution for dental and/or contrast media use
USD824525S1 (en) 2014-09-25 2018-07-31 Ethicon Llc Release paper for wound treament devices
EP3244800A1 (en) 2015-01-12 2017-11-22 Real Time Imaging Technologies, LLC Low-dose x-ray imaging system
US10792024B2 (en) 2016-09-28 2020-10-06 Ethicon, Inc. Scaffolds with channels for joining layers of tissue at discrete points
US10470934B2 (en) 2016-09-29 2019-11-12 Ethicon, Inc. Methods and devices for skin closure
US10687986B2 (en) 2016-09-29 2020-06-23 Ethicon, Inc. Methods and devices for skin closure
USD848624S1 (en) 2016-09-29 2019-05-14 Ethicon, Inc. Release paper for wound treatment devices
US10470935B2 (en) 2017-03-23 2019-11-12 Ethicon, Inc. Skin closure systems and devices of improved flexibility and stretchability for bendable joints
US11504446B2 (en) 2017-04-25 2022-11-22 Ethicon, Inc. Skin closure devices with self-forming exudate drainage channels
US10993708B2 (en) 2018-07-31 2021-05-04 Ethicon, Inc. Skin closure devices with interrupted closure
CN109303918A (en) * 2018-09-28 2019-02-05 中国人民解放军军事科学院军事医学研究院 It can be used for the cyanoacrylate and combinations thereof of cutaneous penetration

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5684042A (en) * 1997-01-10 1997-11-04 Medlogic Global Corporation Cyanoacrylate compositions comprising an antimicrobial agent
WO1999055374A1 (en) * 1998-04-30 1999-11-04 Closure Medical Corporation Use of an adhesive composition over a bioactive polymerization initiator or accelerator
WO2000038777A1 (en) * 1998-12-23 2000-07-06 Closure Medical Corporation Applicator for dispensable liquids

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2721858A (en) 1954-03-10 1955-10-25 Eastman Kodak Co Method of making alpha-cyanoacrylates
US3254111A (en) 1960-12-09 1966-05-31 Eastman Kodak Co Esters of alpha-cyanoacrylic acid and process for the manufacture thereof
US3483870A (en) 1963-04-22 1969-12-16 Eastman Kodak Co Surgical use of adhesive compositions
US3554990A (en) 1968-06-10 1971-01-12 Eastman Kodak Co Esters of 2-cyanopenta-2,4-dienoic acid and polymers thereof
US3940362A (en) 1972-05-25 1976-02-24 Johnson & Johnson Cross-linked cyanoacrylate adhesive compositions
US3964643A (en) 1973-12-27 1976-06-22 L'oreal Unpressurized container for holding a plurality of products separately and dispensing them simultaneously
US4315998A (en) 1974-06-12 1982-02-16 Research Corporation Polymer-bound photosensitizing catalysts
US3995641A (en) 1975-04-23 1976-12-07 Ethicon, Inc. Surgical adhesives
US4042442A (en) 1976-11-29 1977-08-16 Eastman Kodak Company 2-Cyanoacrylate adhesive composition
US4127382A (en) 1977-04-21 1978-11-28 Perry Ronald S Process for the reduction of free formaldehyde on textile fabrics
US4125494A (en) 1977-08-12 1978-11-14 National Starch And Chemical Corporation Adhesion promoter for 2-cyanoacrylate adhesive compositions
JPS56135455A (en) 1980-03-27 1981-10-22 Toagosei Chem Ind Co Ltd Novel 2-cyanoacrylate and curable composition
US4359454A (en) 1980-12-16 1982-11-16 World Health Organization Method and composition containing MCA for female sterilization
RO81169A2 (en) 1980-12-30 1983-02-01 Intreprinderea De Medicamente "Terapia",Ro ORAL TABLETS WITH ANTIMICROBIAL ACTION AND ANTIFUNGICE
JPS5822196A (en) 1981-08-01 1983-02-09 Mitsubishi Paper Mills Ltd Micro capsule composition
US4892736A (en) 1983-10-07 1990-01-09 The Forsyth Dental Infirmary For Children Intra-pocket drug delivery devices for treatment of periodontal diseases
US4764377A (en) 1983-10-07 1988-08-16 The Forsyth Dental Infirmary For Children Intra-pocket drug delivery devices for treatment of periodontal diseases
US4532183A (en) 1983-10-13 1985-07-30 The Mead Corporation Method for producing microcapsules by interfacial photopolymerization and microcapsules formed thereby
AU4554385A (en) 1984-07-31 1986-02-06 Loctite Corporation Adhesive dispenser
US4669491A (en) 1984-08-02 1987-06-02 Renee Weisberg Compositions and process for applying protective covering and extensions to fingernails
JPH0641547B2 (en) 1985-04-01 1994-06-01 三井東圧化学株式会社 Reactive polymer composition
DE3513938A1 (en) 1985-04-18 1986-10-23 Merck Patent Gmbh, 6100 Darmstadt CYTOSTATIC-CONTAINING PHARMACADEPOT
US4980086A (en) 1985-10-16 1990-12-25 Toagosei Chemical Industry, Co., Ltd. Curable composition
EP0247726A3 (en) 1986-04-30 1988-08-31 BP Chemicals Limited Rapid cure acrylic adhesive compositions
JPS62260879A (en) 1986-05-07 1987-11-13 Matsumoto Seiyaku Kogyo Kk Adhesive composition
JPH07100647B2 (en) 1987-05-30 1995-11-01 森村商事株式会社 Temperature-sensitive discoloration manicure
US4915694A (en) 1987-10-02 1990-04-10 Vitaphore Corporation Antimicrobial wound dressing and skin fixator for percutaneous conduits
US4861652A (en) 1987-10-13 1989-08-29 Kimberly-Clark Corporation Diaper article with elasticized waist panel
DE68907377T2 (en) 1988-03-11 1993-12-09 Nisshin Oil Mills Ltd Agent and device for the determination of antigens or antibodies.
US5324520A (en) 1988-12-19 1994-06-28 Vipont Pharmaceutical, Inc. Intragingival delivery systems for treatment of periodontal disease
US4940579A (en) 1988-12-27 1990-07-10 Minnesota Mining And Manufacturing Company Topical application of medicament in a binder
US5061286A (en) 1989-08-18 1991-10-29 Osteotech, Inc. Osteoprosthetic implant
WO1991003921A1 (en) 1989-08-29 1991-03-21 At&E Corporation Watchband battery powered system
DE4100176A1 (en) 1991-01-05 1992-07-09 Hoechst Ag PYRIMIDINCYCLOHEXAN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN LIQUID CRYSTALLINE MIXTURES
JPH04313341A (en) 1991-04-11 1992-11-05 Mitsubishi Paper Mills Ltd Production of colored microcapsule
US5259835A (en) 1991-08-29 1993-11-09 Tri-Point Medical L.P. Wound closure means and method using flowable adhesive
US5262200A (en) 1992-03-27 1993-11-16 Alan Puder System and method of applying cyanoacrylate adhesive activator
DE4220736A1 (en) 1992-06-25 1994-01-05 Puetter Medice Chem Pharm Inclusion complexes of polymerized cyclodextrins with pharmaceutically active substances
US5254132A (en) 1992-09-01 1993-10-19 Medlogic, Inc. Methods for treating suturable wounds by use of sutures and cyanoacrylate adhesives
JP2722444B2 (en) 1993-03-19 1998-03-04 日本製紙株式会社 Method for producing microcapsules
US5624669A (en) 1993-03-31 1997-04-29 Tri-Point Medical Corporation Method of hemostatic sealing of blood vessels and internal organs
US5328687A (en) 1993-03-31 1994-07-12 Tri-Point Medical L.P. Biocompatible monomer and polymer compositions
DE69426530D1 (en) 1993-10-04 2001-02-08 Maurizio Tonetti PHARMACEUTICAL COMPOSITION TO PROMOTE TISSUE HEALING AND REGENERATION AND PHARMACEUTICAL SET
US5762955A (en) 1994-02-04 1998-06-09 Smith; Stephen Jay Method for application and maintenance of medication on body tissue
US5580565A (en) 1994-09-01 1996-12-03 Medlogic Global Corporation Use of cyanoacrylate adhesives for providing a protective barrier film for the skin
US5480935A (en) 1994-09-01 1996-01-02 Medlogic Global Corporation Cyanoacrylate adhesive compositions
US6001213A (en) 1994-10-13 1999-12-14 Loctite Corporation Methods for forming non-environmentally hazardous, non-volatile adhesive promoter compositions for curing adhesives
US5900245A (en) 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
US5981621A (en) * 1996-02-29 1999-11-09 Closure Medical Corporation Monomeric compositions effective as wound closure devices
US5928611A (en) 1995-06-07 1999-07-27 Closure Medical Corporation Impregnated applicator tip
JPH0952814A (en) 1995-08-09 1997-02-25 Sunstar Inc Skin cosmetic composition
US5866106A (en) 1997-02-03 1999-02-02 Pacer Technology Vitamin/mineral-enriched cyanoacrylate cosmetic
FR2760971B1 (en) 1997-03-20 1999-12-10 Dow Corning Sa PROCESS FOR PRODUCING A CONTROLLED RELEASE COMPOSITION
US5811471A (en) 1997-09-15 1998-09-22 Shanbrom Technologies Llc Disinfectant plastic sponge material
US5906825A (en) 1997-10-20 1999-05-25 Magellan Companies, Inc. Polymers containing antimicrobial agents and methods for making and using same
GB9722862D0 (en) 1997-10-29 1997-12-24 Horsell Graphic Ind Ltd Pattern formation
WO1999023150A1 (en) 1997-11-03 1999-05-14 Medlogic Global Corporation Cyanoacrylate polymer compositions comprising an antimicrobial agent
US6090397A (en) 1997-11-03 2000-07-18 Medlogic Global Corporation Kits containing cyanoacrylate compositions comprising an antimicrobial agent
US5962010A (en) 1997-11-03 1999-10-05 Medlogic Global Corporation Methods and compositions for treating dermatoses
WO1999030629A1 (en) 1997-12-17 1999-06-24 Hemodynamics, Inc. Sealing media for surgery and wound closure

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5684042A (en) * 1997-01-10 1997-11-04 Medlogic Global Corporation Cyanoacrylate compositions comprising an antimicrobial agent
WO1999055374A1 (en) * 1998-04-30 1999-11-04 Closure Medical Corporation Use of an adhesive composition over a bioactive polymerization initiator or accelerator
WO2000038777A1 (en) * 1998-12-23 2000-07-06 Closure Medical Corporation Applicator for dispensable liquids

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE COMPENDEX [online] ENGINEERING INFORMATION, INC., NEW YORK, NY, US; RAMARAJ B ET AL: "Hydrogel capsules for sustained drug release", XP002170379, Database accession no. EIX94061904376 *
J APPL POLYM SCI;JOURNAL OF APPLIED POLYMER SCIENCE FEB 7 1994 PUBL BY JOHN WILEY & SONS INC, NEW YORK, NY, USA, vol. 51, no. 6, 7 February 1994 (1994-02-07), pages 979 - 988 *

Also Published As

Publication number Publication date
WO2001030408A2 (en) 2001-05-03
AU3637501A (en) 2001-05-08
US6455064B1 (en) 2002-09-24

Similar Documents

Publication Publication Date Title
WO2001030408A3 (en) Adhesive composition over a bioactive polymerization initiator
MXPA03000782A (en) Absorbable adhesive compositions.
WO2005011769A3 (en) Implantable or insertable medical devices containing acrylic copolymer for controlled delivery of therapeutic agent
CA2280495A1 (en) Bonding compositions for dental use
AU2623201A (en) Controlled delivery of therapeutic agents by insertable medical devices
CA2424029A1 (en) Coated medical devices
WO2002047731A3 (en) Drug delivery compositions and coated medical devices
WO2004010975A3 (en) Controlled drug delivery
MXPA03006825A (en) Coated vascular devices.
WO1995028124A3 (en) An adjunctive polymer system for use with medical device
EP1586338A3 (en) The use of antioxidants to prevent oxidation and reduce drug degradation in drug eluting medical devices
MX9703912A (en) Drug releasing surgical implant or dressing material.
WO2001078698A3 (en) Use of ngf-antagonists for the prevention or treatment of chronic visceral pain
CA2447302A1 (en) Two-phase, water-absorbent bioadhesive composition
WO2001093890A3 (en) Botulinum toxin implant
ATE371680T1 (en) POLYMER CONJUGATES
EP1447098A3 (en) Therapeutic inhibitor of vascular smooth muscle cells
WO2003039654A3 (en) Radiation seeds having projections and indentations
AU2002213698A1 (en) Needleless syringe for the subcutaneous delivery of therapeutic agents
BR9910063A (en) Set to supply a medicine to a patient, and manufacture a package
FI942922A (en) Acetylsalicylic acid transdermal delivery system for antithrombotic therapy and cancer prevention
WO2000018331A3 (en) Drug delivery systems
CA2294921A1 (en) Levobupivacaine and its use
WO2005055955A3 (en) DOSING METHODS FOR ß-D-2’,3’-DIDEOXY-2’,3’-DIDEHYDRO-5-FLUOROCYTIDINE ANTIVIRAL THERAPY
WO2003087159A3 (en) Modulators of the notch signalling pathway and uses thereof in medical treatment

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP