WO2001043696A3 - Implant device for implanting cell culture - Google Patents

Implant device for implanting cell culture Download PDF

Info

Publication number
WO2001043696A3
WO2001043696A3 PCT/US2000/042628 US0042628W WO0143696A3 WO 2001043696 A3 WO2001043696 A3 WO 2001043696A3 US 0042628 W US0042628 W US 0042628W WO 0143696 A3 WO0143696 A3 WO 0143696A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell culture
implanting
host
implant device
microporous membrane
Prior art date
Application number
PCT/US2000/042628
Other languages
French (fr)
Other versions
WO2001043696A2 (en
WO2001043696A9 (en
Inventor
Stanley D Harpstead
Original Assignee
Rst Implanted Cell Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rst Implanted Cell Technology filed Critical Rst Implanted Cell Technology
Priority to DE60026082T priority Critical patent/DE60026082D1/en
Priority to AU43107/01A priority patent/AU4310701A/en
Priority to EP00992401A priority patent/EP1239898B1/en
Publication of WO2001043696A2 publication Critical patent/WO2001043696A2/en
Publication of WO2001043696A3 publication Critical patent/WO2001043696A3/en
Publication of WO2001043696A9 publication Critical patent/WO2001043696A9/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Prostheses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention provides a device and method for implanting a cell culture in a host. The device includes a biocompatible deformable body, a biocompatible microporous membrane and sealable port. In one embodiment, the device includes an attachment coating covering a surface microporous membrane that facilitates attachment of cells to the microporous membrane. In another embodiment, the device includes an angiogenic coating. The invention also provides a method for implanting a cell culture in a host, administering a therapeutic substance to a host and a method of treating a disease using the device.
PCT/US2000/042628 1999-12-16 2000-12-06 Implant device for implanting cell culture WO2001043696A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE60026082T DE60026082D1 (en) 1999-12-16 2000-12-06 IMPLANT DEVICE FOR IMPLANTING CELL CULTURES
AU43107/01A AU4310701A (en) 1999-12-16 2000-12-06 Implant device and method
EP00992401A EP1239898B1 (en) 1999-12-16 2000-12-06 Implant device for implanting cell culture

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/464,560 US6479066B1 (en) 1999-12-16 1999-12-16 Device having a microporous membrane lined deformable wall for implanting cell cultures
US09/464,560 1999-12-16

Publications (3)

Publication Number Publication Date
WO2001043696A2 WO2001043696A2 (en) 2001-06-21
WO2001043696A3 true WO2001043696A3 (en) 2001-12-13
WO2001043696A9 WO2001043696A9 (en) 2002-05-10

Family

ID=23844412

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/042628 WO2001043696A2 (en) 1999-12-16 2000-12-06 Implant device for implanting cell culture

Country Status (6)

Country Link
US (1) US6479066B1 (en)
EP (1) EP1239898B1 (en)
AT (1) ATE317710T1 (en)
AU (1) AU4310701A (en)
DE (1) DE60026082D1 (en)
WO (1) WO2001043696A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US20030060695A1 (en) * 2001-03-07 2003-03-27 Connelly Patrick R. Implantable artificial organ devices
WO2005107817A2 (en) * 2004-04-30 2005-11-17 Orbus Medical Technologies, Inc. Medical device with coating for capturing genetically-altered cells and methods of using same
KR20170073614A (en) * 2008-03-21 2017-06-28 티슈진, 인코포레이티드 Composition for treatment of intervertebral disc degeneration
US7770941B2 (en) * 2008-04-17 2010-08-10 Onset Pipe Products Ii, Inc. Apparatus and method for supporting a pipe coupling
US20110033515A1 (en) * 2009-08-04 2011-02-10 Rst Implanted Cell Technology Tissue contacting material
AU2016203097A1 (en) * 2009-08-28 2016-06-02 Sernova Corporation Methods And Devices For Cellular Transplantation
NZ598701A (en) 2009-08-28 2014-03-28 Sernova Corp Methods and devices for cellular transplantation
US20120083767A1 (en) 2010-10-01 2012-04-05 The Johns Hopkins University Implantable bioreactor for delivery of paracrine factors
US11338068B2 (en) 2016-11-08 2022-05-24 W. L. Gore & Associates, Inc. Two-part implantable therapy delivery device
JP2022527849A (en) * 2019-03-29 2022-06-06 コロン ティシュージーン，インコーポレイテッド Disc degeneration treatment

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946734A (en) * 1975-02-19 1976-03-30 The United States Of America As Represented By The Secretary Of State Apparatus for controlling the release of a drug
GB2020181A (en) * 1978-05-08 1979-11-14 Pfizer Improved delivery system
GB2178656A (en) * 1985-08-07 1987-02-18 Alza Corp Drug delivery device
WO1996036296A1 (en) * 1995-05-19 1996-11-21 Baxter International Inc. Multiple layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue
US5913998A (en) * 1995-06-07 1999-06-22 Gore Hybrid Technologies, Inc. Method of making an implantable containment apparatus for a therapeutical device

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733336A (en) 1990-10-31 1998-03-31 Baxter International, Inc. Ported tissue implant systems and methods of using same
US5344454A (en) 1991-07-24 1994-09-06 Baxter International Inc. Closed porous chambers for implanting tissue in a host
US5713888A (en) 1990-10-31 1998-02-03 Baxter International, Inc. Tissue implant systems
US5314471A (en) 1991-07-24 1994-05-24 Baxter International Inc. Tissue inplant systems and methods for sustaining viable high cell densities within a host
WO1992007525A1 (en) 1990-10-31 1992-05-14 Baxter International Inc. Close vascularization implant material
US5453278A (en) 1991-07-24 1995-09-26 Baxter International Inc. Laminated barriers for tissue implants
EP0670738A1 (en) 1993-09-24 1995-09-13 Baxter International Inc. Methods for enhancing vascularization of implant devices
US5688237A (en) 1995-05-04 1997-11-18 Cedars-Sinai Medical Center Implantable catheter and method of use

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946734A (en) * 1975-02-19 1976-03-30 The United States Of America As Represented By The Secretary Of State Apparatus for controlling the release of a drug
GB2020181A (en) * 1978-05-08 1979-11-14 Pfizer Improved delivery system
GB2178656A (en) * 1985-08-07 1987-02-18 Alza Corp Drug delivery device
WO1996036296A1 (en) * 1995-05-19 1996-11-21 Baxter International Inc. Multiple layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue
US5913998A (en) * 1995-06-07 1999-06-22 Gore Hybrid Technologies, Inc. Method of making an implantable containment apparatus for a therapeutical device

Also Published As

Publication number Publication date
EP1239898A2 (en) 2002-09-18
WO2001043696A2 (en) 2001-06-21
WO2001043696A9 (en) 2002-05-10
US6479066B1 (en) 2002-11-12
ATE317710T1 (en) 2006-03-15
EP1239898B1 (en) 2006-02-15
DE60026082D1 (en) 2006-04-20
AU4310701A (en) 2001-06-25

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