WO2001048205A3 - Murine neu sequences and methods of use therefor - Google Patents

Murine neu sequences and methods of use therefor Download PDF

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Publication number
WO2001048205A3
WO2001048205A3 PCT/US2000/035648 US0035648W WO0148205A3 WO 2001048205 A3 WO2001048205 A3 WO 2001048205A3 US 0035648 W US0035648 W US 0035648W WO 0148205 A3 WO0148205 A3 WO 0148205A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
sequences
murine
use therefor
neu
Prior art date
Application number
PCT/US2000/035648
Other languages
French (fr)
Other versions
WO2001048205A2 (en
Inventor
A Gregory Spies
Original Assignee
Corixa Corp
A Gregory Spies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp, A Gregory Spies filed Critical Corixa Corp
Priority to AU27442/01A priority Critical patent/AU2744201A/en
Publication of WO2001048205A2 publication Critical patent/WO2001048205A2/en
Publication of WO2001048205A3 publication Critical patent/WO2001048205A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Abstract

The present invention is directed toward murine homologues of human Her-2/neu, as well as pharmaceutical compositions and vaccines comprising such sequences. Murine neu sequences are useful for immunotherapy of Her-2/neu associated cancers.
PCT/US2000/035648 1999-12-29 2000-12-29 Murine neu sequences and methods of use therefor WO2001048205A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU27442/01A AU2744201A (en) 1999-12-29 2000-12-29 Murine neu sequences and methods of use therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47438299A 1999-12-29 1999-12-29
US09/474,382 1999-12-29

Publications (2)

Publication Number Publication Date
WO2001048205A2 WO2001048205A2 (en) 2001-07-05
WO2001048205A3 true WO2001048205A3 (en) 2002-02-07

Family

ID=23883274

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/035648 WO2001048205A2 (en) 1999-12-29 2000-12-29 Murine neu sequences and methods of use therefor

Country Status (2)

Country Link
AU (1) AU2744201A (en)
WO (1) WO2001048205A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2230249A3 (en) 2003-02-06 2010-12-22 ChronTech Pharma AB Antigen/antibody or ligand/receptor glycosylated specificity exchangers

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030514A1 (en) * 1995-03-31 1996-10-03 University Of Washington Intracellular domain of the her-2/neu protein for prevention or treatment of malignancies
US5837243A (en) * 1995-06-07 1998-11-17 Medarex, Inc. Therapeutic compounds comprised of anti-Fc receptor antibodies
WO1999009956A1 (en) * 1997-08-29 1999-03-04 Corixa Corporation Rapid release encapsulated bioactive agents for inducing or potentiating an immune response and methods of using thereof
WO2000044899A1 (en) * 1999-01-29 2000-08-03 Corixa Corporation Her-2/neu fusion proteins
WO2001021192A2 (en) * 1999-09-22 2001-03-29 Corixa Corporation Methods for diagnosis and therapy of hematological and virus-associated malignancies
WO2001053463A2 (en) * 2000-01-21 2001-07-26 Corixa Corporation COMPOUNDS AND METHODS FOR PREVENTION AND TREATMENT OF HER-2/neu ASSOCIATED MALIGNANCIES

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996030514A1 (en) * 1995-03-31 1996-10-03 University Of Washington Intracellular domain of the her-2/neu protein for prevention or treatment of malignancies
US5837243A (en) * 1995-06-07 1998-11-17 Medarex, Inc. Therapeutic compounds comprised of anti-Fc receptor antibodies
WO1999009956A1 (en) * 1997-08-29 1999-03-04 Corixa Corporation Rapid release encapsulated bioactive agents for inducing or potentiating an immune response and methods of using thereof
WO2000044899A1 (en) * 1999-01-29 2000-08-03 Corixa Corporation Her-2/neu fusion proteins
WO2001021192A2 (en) * 1999-09-22 2001-03-29 Corixa Corporation Methods for diagnosis and therapy of hematological and virus-associated malignancies
WO2001053463A2 (en) * 2000-01-21 2001-07-26 Corixa Corporation COMPOUNDS AND METHODS FOR PREVENTION AND TREATMENT OF HER-2/neu ASSOCIATED MALIGNANCIES

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 16 September 1995 (1995-09-16), MOSCOSO ET AL: "Mus musculus tyrosine kinase (erB2) mRNA, partial cds.", XP002178515 *
LIM H ET AL: "Differential expression if the erbB2 gene in the periimplantation mouse uterus: potential mediator of signaling by epidermal growht factor-like growth factors", ENDOCRINOLOGY., vol. 138, no. 3, March 1999 (1999-03-01), BALTIMORE, MD., US, pages 1328 - 1337, XP001028127, ISSN: 0013-7227 *
MOSCOSO LM ET AL: "Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/Heregulin, and its putative receptors, ErbB2 and ErbB3, in developing mammalian muscle", DEVELOPMENTAL BIOLOGY, vol. 172, 1995, ACADEMIC PRESS, NEW YORK, NY, US, pages 158 - 169, XP001027857, ISSN: 0012-1606 *
SLAMON D J ET AL: "STUDIES OF THE HER-2/NEU PROTO-ONCOGENE IN HUMAN BREAST AND OVARIANCANCER", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 244, no. 4905, 12 May 1989 (1989-05-12), pages 707 - 712, XP002019974, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
WO2001048205A2 (en) 2001-07-05
AU2744201A (en) 2001-07-09

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