WO2001052719A3 - Detection of stroke events using diffuse optical tomography - Google Patents

Detection of stroke events using diffuse optical tomography Download PDF

Info

Publication number
WO2001052719A3
WO2001052719A3 PCT/US2001/002226 US0102226W WO0152719A3 WO 2001052719 A3 WO2001052719 A3 WO 2001052719A3 US 0102226 W US0102226 W US 0102226W WO 0152719 A3 WO0152719 A3 WO 0152719A3
Authority
WO
WIPO (PCT)
Prior art keywords
optical tomography
detection
diffuse optical
stroke
patient
Prior art date
Application number
PCT/US2001/002226
Other languages
French (fr)
Other versions
WO2001052719A2 (en
Inventor
David Allan Boas
Original Assignee
Gen Hospital Corp
David Allan Boas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/491,595 external-priority patent/US6516214B1/en
Priority claimed from US09/598,422 external-priority patent/US6577884B1/en
Application filed by Gen Hospital Corp, David Allan Boas filed Critical Gen Hospital Corp
Priority to EP01910346A priority Critical patent/EP1251771A4/en
Priority to AU2001237963A priority patent/AU2001237963A1/en
Priority to CA002397145A priority patent/CA2397145A1/en
Publication of WO2001052719A2 publication Critical patent/WO2001052719A2/en
Publication of WO2001052719A3 publication Critical patent/WO2001052719A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14553—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for cerebral tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04—Arrangements of multiple sensors of the same type
    • A61B2562/046—Arrangements of multiple sensors of the same type in a matrix array

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Physiology (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The invention relates to a method of using diffuse optical tomography and oxygen or dye in a stroke patient, or a patient suspected of having a stroke, to detect ischemic events or bleeds in the brain. The patient is imaged using a plurality of spatially separated light sources (110) for coupling light into tissue and detectors (120) for detecting diffuse light transmitted through the tissue and subsequently analyzed by analyzer (140).
PCT/US2001/002226 2000-01-24 2001-01-23 Detection of stroke events using diffuse optical tomography WO2001052719A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01910346A EP1251771A4 (en) 2000-01-24 2001-01-23 Detection of stroke events using diffuse optical tomography
AU2001237963A AU2001237963A1 (en) 2000-01-24 2001-01-23 Detection of stroke events using diffuse optical tomography
CA002397145A CA2397145A1 (en) 2000-01-24 2001-01-23 Detection of stroke events using diffuse optical tomography

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US17852600P 2000-01-24 2000-01-24
US60/178,526 2000-01-24
US09/491,595 2000-01-25
US09/491,595 US6516214B1 (en) 2000-01-24 2000-01-25 Detection of stroke events using diffuse optical tomography
US09/598,422 2000-06-19
US09/598,422 US6577884B1 (en) 2000-06-19 2000-06-19 Detection of stroke events using diffuse optical tomagraphy

Publications (2)

Publication Number Publication Date
WO2001052719A2 WO2001052719A2 (en) 2001-07-26
WO2001052719A3 true WO2001052719A3 (en) 2001-11-01

Family

ID=27390989

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/002226 WO2001052719A2 (en) 2000-01-24 2001-01-23 Detection of stroke events using diffuse optical tomography

Country Status (4)

Country Link
EP (1) EP1251771A4 (en)
AU (1) AU2001237963A1 (en)
CA (1) CA2397145A1 (en)
WO (1) WO2001052719A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7197355B2 (en) * 2002-04-19 2007-03-27 Visiongate, Inc. Variable-motion optical tomography of small objects

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5803909A (en) * 1994-10-06 1998-09-08 Hitachi, Ltd. Optical system for measuring metabolism in a body and imaging method
US5853370A (en) * 1996-09-13 1998-12-29 Non-Invasive Technology, Inc. Optical system and method for non-invasive imaging of biological tissue
US5902235A (en) * 1989-03-29 1999-05-11 Somanetics Corporation Optical cerebral oximeter
US5954053A (en) * 1995-06-06 1999-09-21 Non-Invasive Technology, Inc. Detection of brain hematoma

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902235A (en) * 1989-03-29 1999-05-11 Somanetics Corporation Optical cerebral oximeter
US5803909A (en) * 1994-10-06 1998-09-08 Hitachi, Ltd. Optical system for measuring metabolism in a body and imaging method
US5954053A (en) * 1995-06-06 1999-09-21 Non-Invasive Technology, Inc. Detection of brain hematoma
US5853370A (en) * 1996-09-13 1998-12-29 Non-Invasive Technology, Inc. Optical system and method for non-invasive imaging of biological tissue

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1251771A4 *

Also Published As

Publication number Publication date
CA2397145A1 (en) 2001-07-26
WO2001052719A2 (en) 2001-07-26
EP1251771A2 (en) 2002-10-30
EP1251771A4 (en) 2005-08-31
AU2001237963A1 (en) 2001-07-31

Similar Documents

Publication Publication Date Title
WO2001092857A3 (en) Dual beam ftir methods and devices for analyte detection in samples of low transmissivity
WO2005012553A3 (en) Optical in vivo probe of analyte concentration within the sterile matrix under the human nail
WO2002090935A3 (en) Diagnostic method for high sensitivity detection of component concentrations in human gas emissions
AU2002358128A1 (en) Method and device for monitoring analyte concentration by optical detection
DK0726729T3 (en) Method and apparatus for analyzing glucose in a biological matrix
CA2332112A1 (en) Monitoring of physiological analytes
DE69942391D1 (en) BLOODY MEASUREMENT OF ANALYTES FROM BLOOD
WO2004021862A3 (en) Improved diffuse optical tomography system and method of use
CA2221864A1 (en) Active pulse blood constituent monitoring
AU2002902A (en) Method for differentiating irritable bowel syndrome from inflammatory bowel disease (ibd) and for monitoring persons with ibd using total endogenous lactoferrinas a marker
AU2303195A (en) Process and device for the analysis of glucose in a biological sample
EP1099102A4 (en) Trace level detection of analytes using artificial olfactometry
ATE389871T1 (en) SYSTEM FOR DETERMINING IN-VIVO STATES IN BODY LUMINA
NO992730L (en) Method and apparatus for blood sampling for diagnostic examination
WO2000006990A3 (en) Apparatus and methods for time-resolved spectroscopic measurements
RU2002135672A (en) METHODS FOR TWO-BEAM IR-FOURIER SPECTROSCOPY AND DEVICES FOR DETECTING THE STUDY IN THE SAMPLES WITH LOW PERMEABILITY
NO982156L (en) Diagnostic test device
AR016908A1 (en) DEVICE, EQUIPMENT AND PROCEDURE TO DETECT THE PRESENCE OF AT LEAST ONE COMPONENT IN A BIOLOGICAL SAMPLE.
MXPA03009111A (en) Biological measurement system.
IL136673A0 (en) A method and device for measuring the concentration of glucose or other substance in blood
JP2004503279A5 (en)
EA200600452A1 (en) AUTOMATED METHODS AND SYSTEMS FOR DETECTION AND ANALYSIS OF VASCULAR PLASTERS
ES2166429T3 (en) ANALYSIS DEVICE INCLUDING A STABLE COPULANT COLOR, FOR THE DETERMINATION OF ANALYTICS.
WO2001042502A3 (en) Methods for disease detection
CA2330629A1 (en) Method and device for predicting physiological values

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US US US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US US US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2397145

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2001910346

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2001910346

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Ref document number: 2001910346

Country of ref document: EP