WO2001062239A3 - Novel compositions and uses of dictyostatin compounds - Google Patents
Novel compositions and uses of dictyostatin compounds Download PDFInfo
- Publication number
- WO2001062239A3 WO2001062239A3 PCT/US2001/006198 US0106198W WO0162239A3 WO 2001062239 A3 WO2001062239 A3 WO 2001062239A3 US 0106198 W US0106198 W US 0106198W WO 0162239 A3 WO0162239 A3 WO 0162239A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dictyostatin
- novel compositions
- compounds
- drug
- dictyostatin compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01911183A EP1259245A2 (en) | 2000-02-24 | 2001-02-26 | Novel compositions and uses of dictyostatin compounds |
CA002400896A CA2400896A1 (en) | 2000-02-24 | 2001-02-26 | Novel compositions and uses of dictyostatin compounds |
JP2001561306A JP2003523383A (en) | 2000-02-24 | 2001-02-26 | Novel compositions and uses of dictyostatin compounds |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18461700P | 2000-02-24 | 2000-02-24 | |
US60/184,617 | 2000-02-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001062239A2 WO2001062239A2 (en) | 2001-08-30 |
WO2001062239A3 true WO2001062239A3 (en) | 2002-01-24 |
Family
ID=22677648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/006198 WO2001062239A2 (en) | 2000-02-24 | 2001-02-26 | Novel compositions and uses of dictyostatin compounds |
Country Status (5)
Country | Link |
---|---|
US (2) | US6576658B2 (en) |
EP (1) | EP1259245A2 (en) |
JP (1) | JP2003523383A (en) |
CA (1) | CA2400896A1 (en) |
WO (1) | WO2001062239A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003263090A1 (en) * | 2002-09-06 | 2004-03-29 | University Of Pittsburgh | Analogs of discodermolide and dictyostatin-1, intermediates therefor and methods of synthesis thereof |
US7321046B2 (en) | 2002-09-06 | 2008-01-22 | University Of Pittsburgh | Analogs of dictyostatin, intermediates therefor and methods of synthesis thereof |
TW200503738A (en) * | 2003-07-16 | 2005-02-01 | Tzu Chi Buddhist General Hospital | Method for extracting antineoplastic components from bupleurum scorzonerifolium |
WO2005042710A1 (en) * | 2003-10-28 | 2005-05-12 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of statin to kill ebv-transformed b cells |
WO2005068451A2 (en) * | 2003-12-31 | 2005-07-28 | Cambridge University Technical Services Limited | Methods for the synthesis of dictyostatin and derivatives and analogues thereof, stereochemical characterisation, novel dictyostatin compounds and uses thereof and synthetic intermediates |
US20050249667A1 (en) * | 2004-03-24 | 2005-11-10 | Tuszynski Jack A | Process for treating a biological organism |
WO2006091728A2 (en) * | 2005-02-24 | 2006-08-31 | The Trustees Of The University Of Pennsylvania | Microtubule stabilizing compounds and methods of their use |
EP1883627B1 (en) | 2005-05-18 | 2018-04-18 | Pharmascience Inc. | Bir domain binding compounds |
EP2024362A4 (en) | 2006-05-16 | 2012-01-25 | Pharmascience Inc | Iap bir domain binding compounds |
AU2011214057B2 (en) | 2010-02-12 | 2016-11-17 | Pharmascience Inc. | IAP BIR domain binding compounds |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0680958A1 (en) * | 1994-04-19 | 1995-11-08 | Arizona Board Of Regents | Isolation and structure of dictyostatin 1 and its use as anti-neoplastic agent |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4206221A (en) | 1979-01-03 | 1980-06-03 | The United States Of America As Represented By The Secretary Of Agriculture | Cephalomannine and its use in treating leukemic tumors |
US5157049A (en) | 1988-03-07 | 1992-10-20 | The United States Of America As Represented By The Department Of Health & Human Services | Method of treating cancers sensitive to treatment with water soluble derivatives of taxol |
US4960790A (en) | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
-
2001
- 2001-02-26 US US09/793,323 patent/US6576658B2/en not_active Expired - Fee Related
- 2001-02-26 EP EP01911183A patent/EP1259245A2/en not_active Withdrawn
- 2001-02-26 JP JP2001561306A patent/JP2003523383A/en active Pending
- 2001-02-26 WO PCT/US2001/006198 patent/WO2001062239A2/en not_active Application Discontinuation
- 2001-02-26 CA CA002400896A patent/CA2400896A1/en not_active Abandoned
-
2003
- 2003-02-06 US US10/360,200 patent/US6677370B2/en not_active Expired - Lifetime
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0680958A1 (en) * | 1994-04-19 | 1995-11-08 | Arizona Board Of Regents | Isolation and structure of dictyostatin 1 and its use as anti-neoplastic agent |
Non-Patent Citations (3)
Title |
---|
D'AMBROSIO, MICHELE ET AL: "On the novel free porphyrins corallistin B, C, D, and E: isolation from the demosponge Corallistes sp. of the Coral Sea and reactivity of their nickel(II) complexes toward formylating reagents", HELV. CHIM. ACTA (1993), 76(4), 1489-96, XP001013065 * |
PETTIT, GEORGE R. ET AL: "Isolation and structure of the cancer cell growth inhibitor dictyostatin 1", J. CHEM. SOC., CHEM. COMMUN. (1994), (9), 1111-12, XP001013066 * |
REIN, T.: "Asymmetric horner-wadsworth-emmons reactions with aldehyde substrates: Scope and synthetic applications.", BOOK OF ABSTRACTS, 213TH ACS NATIONAL MEETING, SAN FRANCISCO, APRIL 13-17 (1997), ORGN-400 PUBLISHER: AMERICAN CHEMICAL SOCIETY, WASHINGTON, D. C., XP001013240 * |
Also Published As
Publication number | Publication date |
---|---|
CA2400896A1 (en) | 2001-08-30 |
US20010056118A1 (en) | 2001-12-27 |
WO2001062239A2 (en) | 2001-08-30 |
US6576658B2 (en) | 2003-06-10 |
JP2003523383A (en) | 2003-08-05 |
EP1259245A2 (en) | 2002-11-27 |
US20030153615A1 (en) | 2003-08-14 |
US6677370B2 (en) | 2004-01-13 |
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