WO2001069245A3 - Cross-reactive sensors - Google Patents

Cross-reactive sensors Download PDF

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Publication number
WO2001069245A3
WO2001069245A3 PCT/US2001/008126 US0108126W WO0169245A3 WO 2001069245 A3 WO2001069245 A3 WO 2001069245A3 US 0108126 W US0108126 W US 0108126W WO 0169245 A3 WO0169245 A3 WO 0169245A3
Authority
WO
WIPO (PCT)
Prior art keywords
cross
detectable agent
interest
reactive
species
Prior art date
Application number
PCT/US2001/008126
Other languages
French (fr)
Other versions
WO2001069245A2 (en
Inventor
David R Walt
Caroline L Schauer
Frank J Steemers
Original Assignee
Tufts College
David R Walt
Caroline L Schauer
Frank J Steemers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tufts College, David R Walt, Caroline L Schauer, Frank J Steemers filed Critical Tufts College
Priority to US10/221,815 priority Critical patent/US7250267B2/en
Priority to AU2001247417A priority patent/AU2001247417A1/en
Publication of WO2001069245A2 publication Critical patent/WO2001069245A2/en
Publication of WO2001069245A3 publication Critical patent/WO2001069245A3/en
Priority to US11/820,882 priority patent/US20100028923A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase

Abstract

The present invention provides a novel cross-reactive sensor system utilizing cross-reactive recognition elements. In the inventive system, each of said one or more cross-reactive recognition elements is capable of interacting with more than one species of liquid analyte of interest, whereby each of said one or more cross-reactive recognition elements reacts in a different manner with each of said one or more species of liquid analytes of interest to produce a detectable agent of each analyte of interest, whereby said detectable agent is analyzed and the information is processed for data acquisition and interpretation. In certain preferred embodiments, the detectable agent and/or change is detected directly, while in certain other preferred embodiments, the detectable agent and/or change is detected with the help of a transducing agent capable of relaying information about each detectable agent generated for each of said species of liquid analyte of interest, whereby said information is processed for data acquisition and interpretation. The present invention also provides method for the analysis of analytes comprising contacting one or more analytes with the inventive system described above.
PCT/US2001/008126 2000-03-14 2001-03-14 Cross-reactive sensors WO2001069245A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/221,815 US7250267B2 (en) 2000-03-14 2001-03-14 Cross-reactive sensors
AU2001247417A AU2001247417A1 (en) 2000-03-14 2001-03-14 Cross-reactive sensors
US11/820,882 US20100028923A1 (en) 2000-03-14 2007-06-21 Cross-reactive sensors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18920000P 2000-03-14 2000-03-14
US60/189,200 2000-03-14

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/820,882 Division US20100028923A1 (en) 2000-03-14 2007-06-21 Cross-reactive sensors

Publications (2)

Publication Number Publication Date
WO2001069245A2 WO2001069245A2 (en) 2001-09-20
WO2001069245A3 true WO2001069245A3 (en) 2002-05-02

Family

ID=22696352

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/008126 WO2001069245A2 (en) 2000-03-14 2001-03-14 Cross-reactive sensors

Country Status (3)

Country Link
US (2) US7250267B2 (en)
AU (1) AU2001247417A1 (en)
WO (1) WO2001069245A2 (en)

Cited By (1)

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CN102667447A (en) * 2009-11-30 2012-09-12 通用电气健康护理生物科学股份公司 Method and system for binding behavior analysis

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AU2001247417A1 (en) * 2000-03-14 2001-09-24 Trustees Of Tufts College Cross-reactive sensors
CA2547331A1 (en) * 2002-11-25 2004-06-10 Tufts University Electro-optical nucleic acid-based sensor array and method for detecting analytes
WO2006047038A1 (en) * 2004-09-28 2006-05-04 Trustees Of Tufts College Apparatus and method for cell migration assays
WO2007057473A1 (en) * 2005-11-21 2007-05-24 Kurt Hoffmann Method for the detection of decomposition processes
US8492098B2 (en) * 2006-02-21 2013-07-23 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
US11237171B2 (en) 2006-02-21 2022-02-01 Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
US20110195852A1 (en) * 2007-08-30 2011-08-11 Trustees Of Tufts College Methods for determining the concentration of an analyte in solution
US20100075862A1 (en) * 2008-09-23 2010-03-25 Quanterix Corporation High sensitivity determination of the concentration of analyte molecules or particles in a fluid sample
US8222047B2 (en) 2008-09-23 2012-07-17 Quanterix Corporation Ultra-sensitive detection of molecules on single molecule arrays
US20100075439A1 (en) * 2008-09-23 2010-03-25 Quanterix Corporation Ultra-sensitive detection of molecules by capture-and-release using reducing agents followed by quantification
WO2011065912A1 (en) * 2009-11-30 2011-06-03 Ge Healthcare Bio-Sciences Ab Method and system for interaction analysis
US9678068B2 (en) * 2010-03-01 2017-06-13 Quanterix Corporation Ultra-sensitive detection of molecules using dual detection methods
US8415171B2 (en) * 2010-03-01 2013-04-09 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
JP5363663B2 (en) 2010-03-01 2013-12-11 クワンテリクス コーポレーション Method or system for extending the dynamic range in an assay to detect molecules or particles
US8236574B2 (en) 2010-03-01 2012-08-07 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
US9952237B2 (en) 2011-01-28 2018-04-24 Quanterix Corporation Systems, devices, and methods for ultra-sensitive detection of molecules or particles
US20140302532A1 (en) 2011-04-12 2014-10-09 Quanterix Corporation Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury
US9932626B2 (en) 2013-01-15 2018-04-03 Quanterix Corporation Detection of DNA or RNA using single molecule arrays and other techniques
US9689046B2 (en) 2013-09-20 2017-06-27 Fredsense Technologies Corp. System and methods for the detection of multiple chemical compounds
WO2017096492A1 (en) * 2015-12-11 2017-06-15 Mcmaster University Nucleic acid catenane with a linking duplex biosensor for detection of a microorganism target
US10054543B2 (en) 2016-02-23 2018-08-21 The United States Of America, As Represented By The Secretary Of The Army Multi-dimensional cross-reactive array for chemical sensing
CN112730275B (en) * 2021-02-04 2023-06-30 华东理工大学 Microscopic spectrum imaging system, pesticide detection system and method thereof

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US5320814A (en) * 1991-01-25 1994-06-14 Trustees Of Tufts College Fiber optic array sensors, apparatus, and methods for concurrently visualizing and chemically detecting multiple analytes of interest in a fluid sample
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US5320814A (en) * 1991-01-25 1994-06-14 Trustees Of Tufts College Fiber optic array sensors, apparatus, and methods for concurrently visualizing and chemically detecting multiple analytes of interest in a fluid sample
US5690894A (en) * 1995-05-23 1997-11-25 The Regents Of The University Of California High density array fabrication and readout method for a fiber optic biosensor
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102667447A (en) * 2009-11-30 2012-09-12 通用电气健康护理生物科学股份公司 Method and system for binding behavior analysis
CN102667447B (en) * 2009-11-30 2016-03-23 通用电气健康护理生物科学股份公司 For the method and system that bonding behavior is analyzed

Also Published As

Publication number Publication date
US7250267B2 (en) 2007-07-31
US20100028923A1 (en) 2010-02-04
AU2001247417A1 (en) 2001-09-24
WO2001069245A2 (en) 2001-09-20
US20070122861A1 (en) 2007-05-31

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