WO2001070104B1 - Method and apparatus for diagnosis and treatment of arrhythmias - Google Patents

Method and apparatus for diagnosis and treatment of arrhythmias

Info

Publication number
WO2001070104B1
WO2001070104B1 PCT/US2001/008731 US0108731W WO0170104B1 WO 2001070104 B1 WO2001070104 B1 WO 2001070104B1 US 0108731 W US0108731 W US 0108731W WO 0170104 B1 WO0170104 B1 WO 0170104B1
Authority
WO
WIPO (PCT)
Prior art keywords
patient
depolarizations
intervals
heart
expected range
Prior art date
Application number
PCT/US2001/008731
Other languages
French (fr)
Other versions
WO2001070104A3 (en
WO2001070104A2 (en
Inventor
Robert W Stadler
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Priority to DE60108230T priority Critical patent/DE60108230T2/en
Priority to EP01918821A priority patent/EP1267993B1/en
Publication of WO2001070104A2 publication Critical patent/WO2001070104A2/en
Publication of WO2001070104A3 publication Critical patent/WO2001070104A3/en
Publication of WO2001070104B1 publication Critical patent/WO2001070104B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362Heart stimulators
    • A61N1/3621Heart stimulators for treating or preventing abnormally high heart rate
    • A61N1/3622Heart stimulators for treating or preventing abnormally high heart rate comprising two or more electrodes co-operating with different heart regions

Abstract

A third generation adaptive new ST Rule that provides a more accurate ST detection mechanism for next generation cardiac pacemakers, ICDs, drug pumps, monitors or other devices. The new ST Rule is a rule which, when met, may control delivery or withholding of therapy. The new ST Rule includes an adaptive onset criteria. An expected range of RR-intervals is calculated based on a trimmed means and a metric of RR variability to be derived over a preceding series of RR intervals. The expected range is updated adaptively after ventricular events. Preferably, the expected interval range is not adapted to curing on 1:1 rhythms. The activity of the adaptive onset criteria provided by the new ST Rule is further augmented by available atrial information. Specifically, patent codes indicative of gradual rate changes in normal sinus rhythm, if they persist, results in a new ST Rule being made. Patent codes inconsistent with sinus tachycardia, for example, those indicating a non 1:1 rhythm or rapid rate change associated with sudden onset of VT will result in the new ST Rule not being met. Thus, distinctions are met between various tachyarrhythmias to provide appropriate therapies and treat the identified tachyarrhythmias.

Claims

AMENDED CLAIMS[received by the International Bureau on 5 November 2001 (05.11.01); original claims 1-50 replaced by new claims 1-25 (5 pages)]
1. An apparatus for identifying sinus rhythm in a patient's heart, comprising: means for measuring intervals between depolarizations of a single chamber of a patient's heart; means for deriving an average value based upon preceding measured intervals between depolarizations of the single chamber; means for deteπnining a variability value based upon preceding measured intervals between depolarizations of the single chamber; means for defining a first expected range of future measured intervals between depolaπzations of the single chamber based upon the average value; and the variability value; and means responsive to future measured intervals between depolarizations of the single chamber falling within the first expected range, for determining that the patient is in a sinus rhythm.
2. The apparatus of claim 1 wherein the means for deriving the average value comprises means for deriving a mean value of preceding intervals between depolarizations of the single chamber.
3. The apparatus of claim 2 wherein the means for deriving theimean value comprises means for deriving a trimmed mean value of preceding intervals between depolarizations of the single chamber.
4. The apparatus of claim 1 or claim 2 above, wherein the means for measuring intervals between depolarizations of the single chamber comprises means forimeasuring intervals between depolarizations of a ventricle of the paαent's heart.
5. The apparatus of claim 4, further comprising: means for measuring intervals between depolarizations of two chambers of the patient's heart: means for defining a second expected range of future measured intervals between depolarizations of the two chambers; and means responsive to future measured intervals between depolarizations of the two chambers falling within the second expected range, for deteπnining that the patient is in a sinus rhythm.
6. The apparatus of claim 5. further comprising: means for determining whether the patient's heart is in a 1.1 rhythm; and means responsive to a determination that the patient's heart is m a 1.1 rhythm, for determining that the patient is in a sinus rhythm.
7 The apparatus of claim 1 , further comprising: means for measuring intervals between depolarizations of two chambers of the patient's heart; means for defining a second expected range of future measured intervals between depolarizanons of the two chambers; and means responsive to future measured intervals between depolarizations of the two chambers falling withm the second expected range, for determining that the patient is in a smus rhyt m.
S. The apparatus of claim 1 , further comprising: means for determining whether the patient's heart is m a 1.1 rhythm; and means responsive to a determination that the pauent's heart is in a 1 1 rhythm, for determining that the patient is m a sinus rhythm.
9. An apparatus for identifying sinus rhythm a patient's heart, comprising: means for measunng intervals between depolarizations of a single chamber of a patient's heart; means for defining a first expected range of future measured' intervals between depolarizations of the single chamber, based upon the measured intervals between depolarizations of the single chamber; means for determining whether the patient's heart is in a M rhythm; and means responsive to future measured intervals between depolarizations of the single chamber falling within the first expected range while the patient is in a 1:1 rhythm, for determining that the patient is in a sinus rhythm.
10. The apparatus of claim 9 wherein the means for defining the first expected range comprises means for deriving an average value of preceding intervals between depolarizations of the single chamber and means for defining the first expected range based upon the average value.
11. The apparatus of claim 10 wherein the means for deriving the average value compπses means for denving a mean value of preceding intervals between depolarizations of the single chamber.
12. The apparatus of claim 10 or claim 11, wherein the means for defining the first expected range further compπses means for deπvmg a value of the vanabihty of preceding measured intervals between depolanzanoαs of the single chamber and means for defining the first expected range based upon the average value and the vanabihty value.
13. The apparatus of claim 9 or claim 10 or claim 11 , wherein the means for measuring mtervals between depolaπzaπons of the single chamber comprises means for measuring intervals between depolanzattons of a ventricle of the patient's heart
14 The apparatus of claim 13 further compnsing means for measuπng intervals berween depolarizations of two chambers of the patient's heart; means for defining a second expected range of future measured intervals between depolarizations of the two chambers, and means responsive to future measured mtervals between depolarizations of the two chambers of the patient's heart fallmg within the second expected range, for determining that the patient is in a sinus rhythm
15. The apparatus of claim 9, further compnsing means formeasuπng intervals between depolarizations of two chambers of the patient's heart; means for defining a second expected range of future measured mtervals between depolarizations of the two chambers, and means responsive to future measured mtervals berween depolarizations of the two chambers of the patient s heart falling within the second expected range, for determining that the patient is in a smus rhythm.
16 An apparatus for identifying sinus rhythm m a patient's heaπ compnsing: means for measuπng mtervals between depolanzations of a single chamber of a patient's heart; means for measuring intervals between depolaπzations of two chambers of the patient's heart; means for defining a first expected range of future measured intervals between depolarizations of the single chamber of a patient's heart; means for defining a second expected range of future measured mtervals between depolarizations of the two chambers of the patient's heart; and means responsive to future measured intervals between depolarizations of the single chamber of a patient's heart falling withm the first expected range and responsive to future measured intervals between depolaπzanons of the two chambers of the patient's heart falling withm the second expected range for determining that the panent is in a sinus rhythm.
17. The apparatus of claim 16 wherein the means for defining the first expected range comprises means for denving an average value of preceding intervals between depolarizations of the single chamber and means for defining the first expected range based upon the average value.
18. The apparatus of claim 17 wherem the means for deriving the average value comprises means for deriving a mean value of preceding intervals between depolarizations of the single chamber.
19. The apparatus of claim 17 or claim 18, wherein the means for defimng the first expected range further compπses deπvmg a value of the variability of preceding measured intervals and means for defining the first expected range based upon the average value and the variability value.
20. The apparatus of claim 16 or claim 17 or claim 18, wherem the means for measuring intervals between depolaπzations of the single chamber of the patient's heart comprises means for measuring intervals between depolarizations of a ventricle of the patient's heart.
21. The apparatus of claim 16 wherem the means for defining the second expected range compπses means for deriving an average value of preceding mtervals between depolarizations of the two chambers and defimng the second expected range based upon the average value.
22. The apparatus of claim 21 wherein the means for deriving the average value comprises means for deriving a mean value of preceding intervals between depolarizations of the two chambers.
23. The apparatus of claim 21 or claim 22, wherein the means for defining the second expected range further comprises means for deriving a value of the variability of preceding measured intervals and means for defining the second expected range based upon the average value and the variability value.
24. The apparatus of claim 16 or claim 21 or claim 22, wherein the means for measuring intervals between depolaπzations of the two chambers comprises mjeans for measuring intervals between depolarizations of an atrium and a ventricle of the patient's heart.
25. The apparatus of claim 16, further comprising: means for determining whether the patient's heart is in a 1:1 rhythm; and means responsive to a determination that the patient's heart is in a 1:1 rhythm, for determining that the patient is in a sinus rhythm.
PCT/US2001/008731 2000-03-22 2001-03-19 Method and apparatus for diagnosis and treatment of arrhythmias WO2001070104A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE60108230T DE60108230T2 (en) 2000-03-22 2001-03-19 DEVICE FOR DIAGNOSIS AND TREATMENT OF ARRHYTMIES
EP01918821A EP1267993B1 (en) 2000-03-22 2001-03-19 Apparatus for diagnosis and treatment of arrhythmias

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/532,478 2000-03-22
US09/532,478 US6567691B1 (en) 2000-03-22 2000-03-22 Method and apparatus diagnosis and treatment of arrhythias

Publications (3)

Publication Number Publication Date
WO2001070104A2 WO2001070104A2 (en) 2001-09-27
WO2001070104A3 WO2001070104A3 (en) 2002-01-03
WO2001070104B1 true WO2001070104B1 (en) 2002-02-14

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Family Applications (1)

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Country Status (4)

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US (1) US6567691B1 (en)
EP (1) EP1267993B1 (en)
DE (1) DE60108230T2 (en)
WO (1) WO2001070104A2 (en)

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Also Published As

Publication number Publication date
EP1267993A2 (en) 2003-01-02
DE60108230D1 (en) 2005-02-10
WO2001070104A3 (en) 2002-01-03
US6567691B1 (en) 2003-05-20
EP1267993B1 (en) 2005-01-05
DE60108230T2 (en) 2005-12-08
WO2001070104A2 (en) 2001-09-27

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