WO2001071732A3 - Porous ferro- or ferrimagnetic glass particles for isolating molecules - Google Patents

Porous ferro- or ferrimagnetic glass particles for isolating molecules Download PDF

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Publication number
WO2001071732A3
WO2001071732A3 PCT/EP2001/003294 EP0103294W WO0171732A3 WO 2001071732 A3 WO2001071732 A3 WO 2001071732A3 EP 0103294 W EP0103294 W EP 0103294W WO 0171732 A3 WO0171732 A3 WO 0171732A3
Authority
WO
WIPO (PCT)
Prior art keywords
glass particles
ferro
porous
ferrimagnetic
molecules
Prior art date
Application number
PCT/EP2001/003294
Other languages
German (de)
French (fr)
Other versions
WO2001071732B1 (en
WO2001071732A2 (en
Inventor
Philippe Sauer
Bernd Springer
Thomas Manz
Christoph Ritt
Roland Fabis
Original Assignee
Qiagen Gmbh
Philippe Sauer
Bernd Springer
Thomas Manz
Christoph Ritt
Roland Fabis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22708215&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2001071732(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to AU6380001A priority Critical patent/AU6380001A/en
Priority to EP01938032A priority patent/EP1266385B1/en
Priority to JP2001569829A priority patent/JP4907030B2/en
Priority to AU2001263800A priority patent/AU2001263800B2/en
Priority to US10/239,112 priority patent/US7183002B2/en
Application filed by Qiagen Gmbh, Philippe Sauer, Bernd Springer, Thomas Manz, Christoph Ritt, Roland Fabis filed Critical Qiagen Gmbh
Priority to DE60137203T priority patent/DE60137203D1/en
Priority to CA002400724A priority patent/CA2400724C/en
Publication of WO2001071732A2 publication Critical patent/WO2001071732A2/en
Publication of WO2001071732A3 publication Critical patent/WO2001071732A3/en
Publication of WO2001071732B1 publication Critical patent/WO2001071732B1/en
Priority to US11/635,304 priority patent/US7922917B2/en
Priority to US13/034,217 priority patent/US8202427B2/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0054—Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y10T428/2996—Glass particles or spheres
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Power Engineering (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Iron (AREA)
  • Surface Treatment Of Glass (AREA)
  • Peptides Or Proteins (AREA)
  • Hard Magnetic Materials (AREA)
  • Saccharide Compounds (AREA)
  • Soft Magnetic Materials (AREA)

Abstract

Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules, under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use of identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
PCT/EP2001/003294 2000-03-24 2001-03-22 Porous ferro- or ferrimagnetic glass particles for isolating molecules WO2001071732A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CA002400724A CA2400724C (en) 2000-03-24 2001-03-22 Porous ferro- or ferrimagnetic glass particles for isolating molecules
EP01938032A EP1266385B1 (en) 2000-03-24 2001-03-22 Porous ferro- or ferrimagnetic glass particles for isolating molecules
JP2001569829A JP4907030B2 (en) 2000-03-24 2001-03-22 Porous ferromagnetic or ferrimagnetic glass particles for molecular isolation
AU2001263800A AU2001263800B2 (en) 2000-03-24 2001-03-22 Porous ferro- or ferrimagnetic glass particles for isolating molecules
US10/239,112 US7183002B2 (en) 2000-03-24 2001-03-22 Porous ferro- or ferrimagnetic glass particles for isolating molecules
AU6380001A AU6380001A (en) 2000-03-24 2001-03-22 Porous ferro- or ferrimagnetic glass particles for isolating molecules
DE60137203T DE60137203D1 (en) 2000-03-24 2001-03-22 Porous ferric or ferrimagnetic glass particles for molecular extraction
US11/635,304 US7922917B2 (en) 2000-03-24 2006-12-07 Porous ferro- or ferrimagnetic glass particles for isolating molecules
US13/034,217 US8202427B2 (en) 2000-03-24 2011-02-24 Porous ferro-or ferrimagnetic glass particles for isolating molecules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19209300P 2000-03-24 2000-03-24
US60/192,093 2000-03-24

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10239112 A-371-Of-International 2001-03-22
US11/635,304 Division US7922917B2 (en) 2000-03-24 2006-12-07 Porous ferro- or ferrimagnetic glass particles for isolating molecules

Publications (3)

Publication Number Publication Date
WO2001071732A2 WO2001071732A2 (en) 2001-09-27
WO2001071732A3 true WO2001071732A3 (en) 2002-01-03
WO2001071732B1 WO2001071732B1 (en) 2002-02-28

Family

ID=22708215

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/003294 WO2001071732A2 (en) 2000-03-24 2001-03-22 Porous ferro- or ferrimagnetic glass particles for isolating molecules

Country Status (8)

Country Link
US (3) US7183002B2 (en)
EP (1) EP1266385B1 (en)
JP (2) JP4907030B2 (en)
AT (1) ATE419629T1 (en)
AU (2) AU6380001A (en)
CA (1) CA2400724C (en)
DE (1) DE60137203D1 (en)
WO (1) WO2001071732A2 (en)

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US7871827B2 (en) 2001-12-20 2011-01-18 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using anion exchange
US7939249B2 (en) 2003-12-24 2011-05-10 3M Innovative Properties Company Methods for nucleic acid isolation and kits using a microfluidic device and concentration step

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AU6380001A (en) * 2000-03-24 2001-10-03 Qiagen Gmbh Porous ferro- or ferrimagnetic glass particles for isolating molecules
GB0116359D0 (en) * 2001-07-04 2001-08-29 Genovision As Preparation of polymer particles
US7347976B2 (en) 2001-12-20 2008-03-25 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix
DE10201084A1 (en) * 2002-01-14 2003-07-24 Bayer Ag Magnetic particles containing silicon, process for their production and use of the particles
GB0215185D0 (en) 2002-07-01 2002-08-07 Genovision As Binding a target substance
AU2003302247A1 (en) * 2002-12-12 2004-07-09 Mykrolis Corporation Porous sintered composite materials
US7981600B2 (en) 2003-04-17 2011-07-19 3M Innovative Properties Company Methods and devices for removal of organic molecules from biological mixtures using an anion exchange material that includes a polyoxyalkylene
US20050059024A1 (en) 2003-07-25 2005-03-17 Ambion, Inc. Methods and compositions for isolating small RNA molecules
CN1878866B (en) † 2003-07-25 2012-08-01 安比恩股份有限公司 Methods and compositions for preparing RNA from a fixed sample
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DE10355409A1 (en) * 2003-11-25 2005-06-30 Magnamedics Gmbh Spherical, magnetic silica gel carriers with increased surface area for the purification of nucleic acids
US7727710B2 (en) 2003-12-24 2010-06-01 3M Innovative Properties Company Materials, methods, and kits for reducing nonspecific binding of molecules to a surface
WO2005079984A1 (en) * 2004-02-18 2005-09-01 Applera Corporation Polyelectrolyte-coated size-exclusion ion-exchange particles
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JP5007920B2 (en) * 2005-08-31 2012-08-22 日立金属株式会社 Nucleic acid extraction method, cancer cell detection method and magnetic beads
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