WO2001078580A3 - A method combining inducing hypothermia and administering a therapeutic agent - Google Patents

A method combining inducing hypothermia and administering a therapeutic agent Download PDF

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Publication number
WO2001078580A3
WO2001078580A3 PCT/US2001/009906 US0109906W WO0178580A3 WO 2001078580 A3 WO2001078580 A3 WO 2001078580A3 US 0109906 W US0109906 W US 0109906W WO 0178580 A3 WO0178580 A3 WO 0178580A3
Authority
WO
WIPO (PCT)
Prior art keywords
patient
heat transfer
blood
administering
transfer element
Prior art date
Application number
PCT/US2001/009906
Other languages
French (fr)
Other versions
WO2001078580A2 (en
Inventor
John D Dobak Iii
Original Assignee
Innercool Therapies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/539,932 external-priority patent/US6491039B1/en
Application filed by Innercool Therapies Inc filed Critical Innercool Therapies Inc
Priority to EP01920828A priority Critical patent/EP1267760A2/en
Priority to AU2001247841A priority patent/AU2001247841A1/en
Priority to JP2001575887A priority patent/JP2003530185A/en
Publication of WO2001078580A2 publication Critical patent/WO2001078580A2/en
Publication of WO2001078580A3 publication Critical patent/WO2001078580A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0212—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0231—Characteristics of handpieces or probes
    • A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The use of an intravascular cooling element to induce hypothermia in connection with a medical procedure. According to a first aspect of the present, invention, a coronary bypass procedure is conducted in which a patient's blood is oxygenated with the patient's lungs and in which blood is circulated using the patient's heart or using an intracorporeal pump. The procedure preferably comprises: (a) positioning a heat transfer element in a blood vessel patient; (b) cooling the body of the patient to less than 35°C, more preferably 32±2°C, using the heat transfer element; and (c) forming a fluid communicating graft between an arterial blood supply and the coronary artery. The body of the patient is preferably heated to about 37°C using the heat transfer element subsequent to the step of forming the fluid communicating graft.
PCT/US2001/009906 2000-03-31 2001-03-28 A method combining inducing hypothermia and administering a therapeutic agent WO2001078580A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01920828A EP1267760A2 (en) 2000-03-31 2001-03-28 Medical procedure
AU2001247841A AU2001247841A1 (en) 2000-03-31 2001-03-28 Medical procedure
JP2001575887A JP2003530185A (en) 2000-03-31 2001-03-28 Medical law

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/539,932 2000-03-31
US09/539,932 US6491039B1 (en) 1998-01-23 2000-03-31 Medical procedure
US65895000A 2000-09-11 2000-09-11
US09/658,950 2000-09-11

Publications (2)

Publication Number Publication Date
WO2001078580A2 WO2001078580A2 (en) 2001-10-25
WO2001078580A3 true WO2001078580A3 (en) 2002-01-31

Family

ID=27066259

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/009906 WO2001078580A2 (en) 2000-03-31 2001-03-28 A method combining inducing hypothermia and administering a therapeutic agent

Country Status (4)

Country Link
EP (1) EP1267760A2 (en)
JP (1) JP2003530185A (en)
AU (1) AU2001247841A1 (en)
WO (1) WO2001078580A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005034966A1 (en) * 2003-10-10 2005-04-21 Protexeon Limited Use of xenon with hypothermia for treating neonatal asphyxia
GB2527075A (en) 2014-03-17 2015-12-16 Daassist As Percutaneous system, devices and methods
US10893847B2 (en) 2015-12-30 2021-01-19 Nuheart As Transcatheter insertion system
US10335528B2 (en) 2016-10-07 2019-07-02 Nuheart As Transcatheter method and system for the delivery of intracorporeal devices
US10537672B2 (en) 2016-10-07 2020-01-21 Nuheart As Transcatheter device and system for the delivery of intracorporeal devices
US10537670B2 (en) 2017-04-28 2020-01-21 Nuheart As Ventricular assist device and method
US10888646B2 (en) 2017-04-28 2021-01-12 Nuheart As Ventricular assist device and method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837228A (en) * 1979-05-31 1989-06-06 The University Of Mississippi Antiinflammatory and antimicrobial compounds and compositions
US5486204A (en) * 1994-09-20 1996-01-23 University Of Texas Health Science Center Houston Method of treating a non-penetrating head wound with hypothermia
US5957963A (en) * 1998-01-23 1999-09-28 Del Mar Medical Technologies, Inc. Selective organ hypothermia method and apparatus
US6033383A (en) * 1996-12-19 2000-03-07 Ginsburg; Robert Temperature regulating catheter and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4625712A (en) 1983-09-28 1986-12-02 Nimbus, Inc. High-capacity intravascular blood pump utilizing percutaneous access
US5913876A (en) 1996-02-20 1999-06-22 Cardiothoracic Systems, Inc. Method and apparatus for using vagus nerve stimulation in surgery
US6006134A (en) 1998-04-30 1999-12-21 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
US5957879A (en) 1997-01-24 1999-09-28 Heartport, Inc. Methods and devices for maintaining cardiopulmonary bypass and arresting a patient's heart
WO1999048449A1 (en) 1998-03-24 1999-09-30 Innercool Therapies, Inc. Selective organ cooling apparatus and method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837228A (en) * 1979-05-31 1989-06-06 The University Of Mississippi Antiinflammatory and antimicrobial compounds and compositions
US5486204A (en) * 1994-09-20 1996-01-23 University Of Texas Health Science Center Houston Method of treating a non-penetrating head wound with hypothermia
US6033383A (en) * 1996-12-19 2000-03-07 Ginsburg; Robert Temperature regulating catheter and methods
US5957963A (en) * 1998-01-23 1999-09-28 Del Mar Medical Technologies, Inc. Selective organ hypothermia method and apparatus

Also Published As

Publication number Publication date
WO2001078580A2 (en) 2001-10-25
JP2003530185A (en) 2003-10-14
AU2001247841A1 (en) 2001-10-30
EP1267760A2 (en) 2003-01-02

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