WO2001087378A3 - Compressed gas dry powder inhaler - Google Patents

Compressed gas dry powder inhaler Download PDF

Info

Publication number
WO2001087378A3
WO2001087378A3 PCT/US2001/012057 US0112057W WO0187378A3 WO 2001087378 A3 WO2001087378 A3 WO 2001087378A3 US 0112057 W US0112057 W US 0112057W WO 0187378 A3 WO0187378 A3 WO 0187378A3
Authority
WO
WIPO (PCT)
Prior art keywords
dry powder
mouthpiece
powder inhaler
compressed gas
dispersion tube
Prior art date
Application number
PCT/US2001/012057
Other languages
French (fr)
Other versions
WO2001087378A2 (en
Inventor
Vladislav Nodelman
Andrew W Gieschen
Ruijing Han
Jason Passchier
Charles Ganem
Michael Ligotke
Bernard Greenspan
Original Assignee
Dura Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dura Pharma Inc filed Critical Dura Pharma Inc
Priority to AU2001257034A priority Critical patent/AU2001257034A1/en
Publication of WO2001087378A2 publication Critical patent/WO2001087378A2/en
Publication of WO2001087378A3 publication Critical patent/WO2001087378A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means

Abstract

A dry powder inhaler has a dispersion tube (28) extending from a compressed air source (32) to a mouthpiece (24). A dose of dry powder is introduced into the dispersion tube. Upon inhalation on the mouthpiece, a burst or bolus of compressed air is released into the dispersion tube, dispersing the powder and carrying the powder out through the mouthpiece. The dispersed particles are decelerated and inhaled in an inspiratory-flow rate independent manner, and with minimal wall losses. Respirable pharmaceuticals are delivered into the lung, inexpensively, efficiently, consistently and with low losses.
PCT/US2001/012057 2000-05-12 2001-04-12 Compressed gas dry powder inhaler WO2001087378A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001257034A AU2001257034A1 (en) 2000-05-12 2001-04-12 Compressed gas dry powder inhaler

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56985400A 2000-05-12 2000-05-12
US09/569,854 2000-05-12

Publications (2)

Publication Number Publication Date
WO2001087378A2 WO2001087378A2 (en) 2001-11-22
WO2001087378A3 true WO2001087378A3 (en) 2002-04-11

Family

ID=24277157

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/012057 WO2001087378A2 (en) 2000-05-12 2001-04-12 Compressed gas dry powder inhaler

Country Status (2)

Country Link
AU (1) AU2001257034A1 (en)
WO (1) WO2001087378A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9008761B2 (en) 2010-02-01 2015-04-14 Proteus Digital Health, Inc. Two-wrist data gathering system
US9014779B2 (en) 2010-02-01 2015-04-21 Proteus Digital Health, Inc. Data gathering system
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
US9179691B2 (en) 2007-12-14 2015-11-10 Aerodesigns, Inc. Delivering aerosolizable food products

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
FR2849386B1 (en) 2002-12-27 2005-03-18 Bertin Technologies Sa INHALATION DEVICE FOR DRY POWDER
WO2005102429A1 (en) 2004-04-21 2005-11-03 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
JP5241714B2 (en) 2006-07-07 2013-07-17 プロテウス デジタル ヘルス， インコーポレイテッド Smart parenteral delivery system
EP1992377A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992381A1 (en) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992380A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992372A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992379A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992376A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992373A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992374A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
JP2019523109A (en) 2016-05-03 2019-08-22 ニューマ・リスパイラトリー・インコーポレイテッド Systems and methods for lung health management
EP4223335A3 (en) * 2017-05-19 2023-11-08 Pneuma Respiratory, Inc. Dry powder delivery device and methods of use
EP3691728A4 (en) 2017-10-04 2021-06-30 Pneuma Respiratory, Inc. Electronic breath actuated in-line droplet delivery device and methods of use
EP3697481A4 (en) 2017-10-17 2021-07-14 Pneuma Respiratory, Inc. Nasal drug delivery apparatus and methods of use
EP3706843A4 (en) 2017-11-08 2021-08-25 Pneuma Respiratory, Inc. Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use
WO2022271848A1 (en) 2021-06-22 2022-12-29 Pneuma Respiratory, Inc. Droplet delivery device with push ejection
CN114515368B (en) * 2022-02-11 2024-03-22 贝里精英包装(嘉兴)有限公司 Active powder spraying device with automatic counting function

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147166A (en) * 1977-05-02 1979-04-03 American Cyanamid Company Oral inhalator powder dispenser
US4667668A (en) * 1981-07-08 1987-05-26 Aktiebolaget Draco Dosage inhalator
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
US5318015A (en) * 1992-09-03 1994-06-07 Sven Mansson Inhaler having ejector structure that provides primary and secondary atomization of an actuated dose of medicament
US5366122A (en) * 1991-08-27 1994-11-22 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for flowable media
US5524613A (en) * 1993-08-25 1996-06-11 Habley Medical Technology Corporation Controlled multi-pharmaceutical inhaler
US5775320A (en) * 1991-07-02 1998-07-07 Inhale Therapeutic Systems Method and device for delivering aerosolized medicaments
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5875776A (en) * 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
US6003512A (en) * 1997-11-13 1999-12-21 Lovelace Respiratory Research Institute Dust gun-aerosol generator and generation
US6029662A (en) * 1996-04-10 2000-02-29 Pierre Fabre Medicament Compressed-air powder inhaler

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147166A (en) * 1977-05-02 1979-04-03 American Cyanamid Company Oral inhalator powder dispenser
US4667668A (en) * 1981-07-08 1987-05-26 Aktiebolaget Draco Dosage inhalator
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
US5775320A (en) * 1991-07-02 1998-07-07 Inhale Therapeutic Systems Method and device for delivering aerosolized medicaments
US5366122A (en) * 1991-08-27 1994-11-22 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for flowable media
US5318015A (en) * 1992-09-03 1994-06-07 Sven Mansson Inhaler having ejector structure that provides primary and secondary atomization of an actuated dose of medicament
US5524613A (en) * 1993-08-25 1996-06-11 Habley Medical Technology Corporation Controlled multi-pharmaceutical inhaler
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5875776A (en) * 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
US6029662A (en) * 1996-04-10 2000-02-29 Pierre Fabre Medicament Compressed-air powder inhaler
US6003512A (en) * 1997-11-13 1999-12-21 Lovelace Respiratory Research Institute Dust gun-aerosol generator and generation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
US9179691B2 (en) 2007-12-14 2015-11-10 Aerodesigns, Inc. Delivering aerosolizable food products
US9008761B2 (en) 2010-02-01 2015-04-14 Proteus Digital Health, Inc. Two-wrist data gathering system
US9014779B2 (en) 2010-02-01 2015-04-21 Proteus Digital Health, Inc. Data gathering system

Also Published As

Publication number Publication date
AU2001257034A1 (en) 2001-11-26
WO2001087378A2 (en) 2001-11-22

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