WO2001091773A3 - Method of stimulating hair growth - Google Patents

Method of stimulating hair growth Download PDF

Info

Publication number
WO2001091773A3
WO2001091773A3 PCT/US2001/017386 US0117386W WO0191773A3 WO 2001091773 A3 WO2001091773 A3 WO 2001091773A3 US 0117386 W US0117386 W US 0117386W WO 0191773 A3 WO0191773 A3 WO 0191773A3
Authority
WO
WIPO (PCT)
Prior art keywords
hair growth
matrix
stimulating hair
oxide inhibitors
intradermal
Prior art date
Application number
PCT/US2001/017386
Other languages
French (fr)
Other versions
WO2001091773A2 (en
Inventor
Anton-Lewis Usala
Original Assignee
Encelle Inc
Usala Anton Lewis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Encelle Inc, Usala Anton Lewis filed Critical Encelle Inc
Priority to CA2410965A priority Critical patent/CA2410965C/en
Priority to AU2001265151A priority patent/AU2001265151A1/en
Publication of WO2001091773A2 publication Critical patent/WO2001091773A2/en
Publication of WO2001091773A3 publication Critical patent/WO2001091773A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/18—Materials or treatment for tissue regeneration for hair reconstruction

Abstract

The invention provides a method of stimulating hair growth, comprising administering a therapeutic amount of a hydrogel matrix to an intradermal or subdermal site where hair growth is desired, the matrix composition comprising gelatin, such as denatured collagen, and a long chain carbohydrate, such as dextran. The matrix may further include polar amino acids, nitric oxide inhibitors and super oxide inhibitors. Injection is a preferred method of administration.
PCT/US2001/017386 2000-05-31 2001-05-30 Method of stimulating hair growth WO2001091773A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA2410965A CA2410965C (en) 2000-05-31 2001-05-30 Method of stimulating hair growth
AU2001265151A AU2001265151A1 (en) 2000-05-31 2001-05-30 Method of stimulating hair growth

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20811600P 2000-05-31 2000-05-31
US60/208,116 2000-05-31

Publications (2)

Publication Number Publication Date
WO2001091773A2 WO2001091773A2 (en) 2001-12-06
WO2001091773A3 true WO2001091773A3 (en) 2002-05-02

Family

ID=22773242

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2001/017387 WO2001091774A2 (en) 2000-05-31 2001-05-30 Method of treating chronic ulcers
PCT/US2001/017386 WO2001091773A2 (en) 2000-05-31 2001-05-30 Method of stimulating hair growth

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2001/017387 WO2001091774A2 (en) 2000-05-31 2001-05-30 Method of treating chronic ulcers

Country Status (8)

Country Link
US (2) US7700660B2 (en)
EP (1) EP1289537B1 (en)
AT (1) ATE311192T1 (en)
AU (3) AU2001263495B2 (en)
CA (2) CA2410968C (en)
DE (1) DE60115433T2 (en)
NZ (1) NZ523461A (en)
WO (2) WO2001091774A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7828749B2 (en) * 1996-05-17 2010-11-09 Roche Diagnostics Operations, Inc. Blood and interstitial fluid sampling device
WO2004082459A2 (en) * 2003-03-13 2004-09-30 Burgess Cheryl M Methods of administering a material into a patient for dermal enhancement
JP2005269232A (en) * 2004-03-18 2005-09-29 Renesas Technology Corp Frequency mixer
US8829051B2 (en) * 2004-05-24 2014-09-09 Geoffrey C. GURTNER Method of treating or preventing pathologic effects of acute increases in hyperglycemia and/or acute increases of free fatty acid flux
WO2009137074A1 (en) * 2008-05-06 2009-11-12 Indigene Pharmaceuticals, Inc. Compositions and methods for treating diabetic ulcers
US10098857B2 (en) 2008-10-10 2018-10-16 The Board Of Trustees Of The Leland Stanford Junior University Topical and transdermal delivery of HIF-1 modulators to prevent and treat chronic wounds
EP2236617A1 (en) * 2009-03-31 2010-10-06 Leukocare Ag Methods of terminal sterilization of biofunctional compositions
AU2010314994B2 (en) 2009-11-09 2016-10-06 Spotlight Technology Partners Llc Fragmented hydrogels
WO2011057131A1 (en) 2009-11-09 2011-05-12 Spotlight Technology Partners Llc Polysaccharide based hydrogels
WO2013067195A1 (en) 2011-11-02 2013-05-10 Halscion, Inc. Methods and compositions for wound treatment
WO2013096650A2 (en) 2011-12-23 2013-06-27 Pioneer Surgical Technology Continuous matrix with osteoconductive particles dispersed therein, method of forming thereof, and method of regenerating bone therewith
US11931325B2 (en) * 2015-10-20 2024-03-19 Eaderm Co., Ltd. Hair-growth promoting composition and usage thereof
KR102085404B1 (en) * 2016-08-31 2020-03-05 주식회사 에스엔비아 Composition for treatment of partial obesity and microneedle comprising the composition
EP3558243B1 (en) 2016-12-21 2022-10-05 Unilever IP Holdings B.V. Personal care compositions comprising poorly soluble compounds
EA038885B1 (en) 2016-12-21 2021-11-02 ЮНИЛЕВЕР АйПи ХОЛДИНГС Б.В. Topical skin lightening additive and composition with amino acids and nicotinamide compounds
CA3046037A1 (en) 2016-12-21 2018-06-28 Unilever Plc Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids
JP7082623B2 (en) 2016-12-21 2022-06-08 ユニリーバー・アイピー・ホールディングス・ベスローテン・ヴェンノーツハップ Composition for personal care with cystine
WO2019055490A1 (en) 2017-09-14 2019-03-21 The Board Of Trustees Of The Leland Stanford Junior University Conditioning irradiated tissue for fat graft retention
JP2021526127A (en) 2018-05-23 2021-09-30 ユニリーバー・ナームローゼ・ベンノートシヤープ Nanoemulsion and its manufacturing method
CN113679846B (en) * 2021-08-31 2023-05-09 佛山市第一人民医院（中山大学附属佛山医院） Hair regenerating agent and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016717A1 (en) * 1992-02-25 1993-09-02 The Rockefeller University Method and agents for promoting wound healing
WO2000002596A1 (en) * 1998-07-10 2000-01-20 Encelle, Inc. Methods for increasing vascularization and promoting wound healing

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198479A (en) 1979-03-30 1980-04-15 Merck & Co., Inc. Replacement of animal serum proteins by human albumin for growth and interferon production by Namalva cells
US4520821A (en) 1982-04-30 1985-06-04 The Regents Of The University Of California Growing of long-term biological tissue correction structures in vivo
US4657866A (en) * 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
US5852009A (en) 1984-03-19 1998-12-22 The Rockefeller University Compositions, including pharmaceutical compositions, for inhibiting the advanced glycosylation of proteins, and therapeutic methods based thereon
US4665192A (en) * 1984-03-19 1987-05-12 The Rockefeller University 2-(2-furoyl)-4(5)-2(furanyl)-1H-imidazole
US4868121A (en) 1985-02-07 1989-09-19 Mcdonnell Douglas Corporation Islet isolation process
NO166836C (en) * 1985-03-14 1991-09-11 Univ California PROCEDURE FOR TREATMENT OF AN ORGAN TRANSPLANT.
AU589438B2 (en) 1985-08-26 1989-10-12 Hana Biologics, Inc. Transplantable artificial tissue and process
US4902295A (en) 1985-08-26 1990-02-20 Hana Biologics, Inc. Transplantable artificial tissue
GB8604497D0 (en) * 1986-02-24 1986-04-03 Connaught Lab Separation of islets of langerhans
FR2600076A1 (en) * 1986-06-12 1987-12-18 Fond Ctre Nal Transfusion CULTURE MEDIUM COMPRISING HUMAN ALBUMIN, PROCESS FOR PREPARING A PRODUCT INJECTABLE THEREFROM, PRODUCT OBTAINED AND USE THEREOF, COMPOSITION OBTAINED
US5079160A (en) * 1987-06-08 1992-01-07 Lacy Paul E Method to isolate clusters of cell subtypes from organs
US5457093A (en) 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
AU632273B2 (en) 1988-03-09 1992-12-24 Terumo Kabushiki Kaisha Medical material permitting cells to enter thereinto and artificial skin
US4950483A (en) * 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
EP0363125A3 (en) 1988-10-03 1990-08-16 Hana Biologics Inc. Proliferated pancreatic endocrine cell product and process
US4957902A (en) 1988-12-20 1990-09-18 Board Of Regents, The University Of Texas System Peptide inhibitors of wound contraction
US5059588A (en) * 1989-10-13 1991-10-22 Procyte Corporation, Incorporated Methods and compositions for healing bone using gly his lys: copper
WO1991009119A1 (en) 1989-12-13 1991-06-27 Trancel Corporation Improved alginate microcapsules, methods of making and using same
US5645591A (en) * 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
US5336616A (en) 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US5192312A (en) * 1991-03-05 1993-03-09 Colorado State University Research Foundation Treated tissue for implantation and methods of treatment and use
DK0585368T3 (en) 1991-04-25 1998-03-16 Univ Brown Res Found Implantable biocompatible immuno-insulating vehicle for delivery of selected therapeutic products
US5605938A (en) 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
CA2071137A1 (en) 1991-07-10 1993-01-11 Clarence C. Lee Composition and method for revitalizing scar tissue
US5591709A (en) 1991-08-30 1997-01-07 Life Medical Sciences, Inc. Compositions and methods for treating wounds
WO1994015589A1 (en) 1992-12-30 1994-07-21 Clover Consolidated, Limited Cytoprotective, biocompatible, retrievable macrocapsule containment systems for biologically active materials
US5358969A (en) * 1991-12-16 1994-10-25 Washington University Method of inhibiting nitric oxide formation
US5246971A (en) 1991-12-16 1993-09-21 Washington University Method of inhibiting nitric oxide formation
US5824331A (en) * 1992-02-24 1998-10-20 Encelle, Inc. Bioartificial devices and cellular matrices therefor
US5834005A (en) 1992-02-24 1998-11-10 Encelle, Inc. Bioartificial devices and cellular matrices therefor
CA2109065C (en) 1992-02-24 2004-03-30 Anton-Lewis Usala Bioartificial endocrine device
US5830492A (en) 1992-02-24 1998-11-03 Encelle, Inc. Bioartificial devices and cellular matrices therefor
US6231881B1 (en) * 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
EP0641196B1 (en) 1992-05-29 2001-08-22 Vivorx, Incorporated Microencapsulation of cells
EP0655910A4 (en) 1992-07-29 1996-02-28 Univ Washington Use of pouch for implantation of living cells.
US5262055A (en) 1992-10-19 1993-11-16 The University Of Utah Implantable and refillable biohybrid artificial pancreas
DE4431598C2 (en) 1993-03-03 1997-03-20 Michael Sittinger Process for producing an implant from cell cultures
DE69434626D1 (en) 1993-11-17 2006-04-20 Athena Neurosciences Inc TRANSPARENT LIQUID FOR THE ADMINISTRATION OF CAPTIVATED MEDICAMENTS
ATE408005T1 (en) 1994-01-13 2008-09-15 Rogosin Inst MACRO-ENCAPSULED SECRETORY CELLS
US5487899A (en) * 1994-01-31 1996-01-30 Jess Clarke & Sons, Inc. Wound healing
US5716404A (en) 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US5840059A (en) * 1995-06-07 1998-11-24 Cardiogenesis Corporation Therapeutic and diagnostic agent delivery
CA2179341A1 (en) 1996-04-12 1997-10-13 Gregory S. Korbutt Methods for isolating, enriching and increasing the maturation of cells
CA2251129A1 (en) * 1996-05-03 1997-11-13 Innogenetics N.V. New medicaments containing gelatin cross-linked with oxidized polysaccharides
US5972332A (en) * 1997-04-16 1999-10-26 The Regents Of The University Of Michigan Wound treatment with keratinocytes on a solid support enclosed in a porous material
EP0986408B1 (en) * 1997-06-03 2005-05-11 Innogenetics N.V. New medicaments based on polymers composed of methacrylamide-modified gelatin
CN1283997A (en) * 1997-12-22 2001-02-14 人类基因组科学公司 Keratinocyte growth factor-2 formulations
US6372494B1 (en) * 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
US6046160A (en) * 1999-07-22 2000-04-04 Deroyal Industries, Inc. Composition and method for enhancing wound healing
US6491953B1 (en) * 2000-01-07 2002-12-10 Amcol International Corporation Controlled release compositions and method
US20020146439A1 (en) * 2000-03-31 2002-10-10 Delong Mitchell Anthony Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016717A1 (en) * 1992-02-25 1993-09-02 The Rockefeller University Method and agents for promoting wound healing
WO2000002596A1 (en) * 1998-07-10 2000-01-20 Encelle, Inc. Methods for increasing vascularization and promoting wound healing

Also Published As

Publication number Publication date
DE60115433D1 (en) 2006-01-05
AU2001265151A1 (en) 2001-12-11
US20020077277A1 (en) 2002-06-20
US20020065222A1 (en) 2002-05-30
NZ523461A (en) 2004-11-26
WO2001091774A2 (en) 2001-12-06
EP1289537B1 (en) 2005-11-30
CA2410965A1 (en) 2001-12-06
ATE311192T1 (en) 2005-12-15
CA2410968C (en) 2011-03-29
AU6349501A (en) 2001-12-11
CA2410968A1 (en) 2001-12-06
EP1289537A2 (en) 2003-03-12
US7700660B2 (en) 2010-04-20
WO2001091774A3 (en) 2002-05-02
DE60115433T2 (en) 2006-08-03
US6992062B2 (en) 2006-01-31
CA2410965C (en) 2010-09-14
AU2001263495B2 (en) 2005-06-02
WO2001091773A2 (en) 2001-12-06

Similar Documents

Publication Publication Date Title
WO2001091773A3 (en) Method of stimulating hair growth
WO2003017826A3 (en) Processed soft tissue for topical or internal application
HUP9904023A2 (en) Use of leptin antagonists for treating insulin resistance in type ii diabetes
EP2158907A3 (en) Topical administration of arginine for pain treatment
WO2004024925A3 (en) Collectin-complement activating protein chimeras
WO2002089794A8 (en) Method for treating neuropathic pain and pharmaceutical preparation therefor
WO2002004008A3 (en) Methods of therapy with thrombin derived peptides
WO2004073616A3 (en) Elastin digest compositions and methods utilizing same
ATE430165T1 (en) PEPTIDES WITH INTEGRIN BINDING MOTIVE AND TREATMENT METHODS FOR MUSCLE DISEASES
MXPA02012075A (en) Composition for pain mediation and apparatus and method of use thereof.
CA2322878A1 (en) Use of selegiline or desmethylselegiline for treating wounds, burns and dermatological damage
WO2003063775A3 (en) Methods and compositions for the promotion of hair growth utilizing actin binding peptides
EP0967276A3 (en) Anti-tumor agent comprising salmosin
JPH0778026B2 (en) Topical base for skin
EP1361905B8 (en) Matrix protein compositions for guided connective tissue growth
WO2002054996A3 (en) Terazosin transdermal device and methods
DK1007085T3 (en) Use of growth hormone in preparations for the treatment of insulin resistance in the heart
WO2004087091A3 (en) Cosmetic or pharmaceutical composition comprising amino acids, use and dermatological treatment methods
CY1108368T1 (en) FELODIPIN INTERIOR DEVICE AND METHODS
WO2004093832A3 (en) Cosmetic or pharmaceutical composition comprising a combination of at least one diacylglycerol and at least one fatty alcohol
MD1469G2 (en) Method of treatment of the burn shock
DE60217302D1 (en) CONSERVATION OF BODY PROTEINS
RS50184B (en) The enzymemucopolysaccharidase based preparation for treatment of cellulitis and process for their obtaining
UA51365A (en) Method for treating pain syndrome in amputation stump
WO2001075057A3 (en) A novel polypeptide, human ribosomal s4 protein 12 and the polynucleotide encoding the polypeptide

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ CZ DE DE DK DK DM DZ EE EE ES FI FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2410965

Country of ref document: CA

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP