WO2001092215A3 - Superoxide-generating diazeniumdiolates, compositions comprising same, and methods for using same - Google Patents
Superoxide-generating diazeniumdiolates, compositions comprising same, and methods for using same Download PDFInfo
- Publication number
- WO2001092215A3 WO2001092215A3 PCT/US2001/017868 US0117868W WO0192215A3 WO 2001092215 A3 WO2001092215 A3 WO 2001092215A3 US 0117868 W US0117868 W US 0117868W WO 0192215 A3 WO0192215 A3 WO 0192215A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- same
- superoxide
- generating
- methods
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
- C07C291/02—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00 containing nitrogen-oxide bonds
- C07C291/08—Azoxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/50—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0206—Polyalkylene(poly)amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/24—Anthracenes; Hydrogenated anthracenes
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2001275155A AU2001275155A1 (en) | 2000-06-02 | 2001-07-01 | Superoxide-generating diazeniumdiolates, compositions comprising same, and methods for using same |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20906700P | 2000-06-02 | 2000-06-02 | |
US60/209,067 | 2000-06-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001092215A2 WO2001092215A2 (en) | 2001-12-06 |
WO2001092215A3 true WO2001092215A3 (en) | 2002-06-27 |
Family
ID=22777186
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/017868 WO2001092215A2 (en) | 2000-06-02 | 2001-06-01 | Superoxide-generating diazeniumdiolates, compositions comprising same, and methods for using same |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2001275155A1 (en) |
WO (1) | WO2001092215A2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9278085B2 (en) | 2006-02-22 | 2016-03-08 | Edison Pharmaceuticals, Inc. | Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
US9399612B2 (en) | 2008-09-10 | 2016-07-26 | Edison Pharmaceuticals, Inc. | Treatment of pervasive developmental disorders with redox-active therapeutics |
US9447006B2 (en) | 2005-06-01 | 2016-09-20 | Edison Pharmaceuticals, Inc. | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002041902A1 (en) * | 2000-11-27 | 2002-05-30 | The University Of Akron | Treatment of disorders using polyethylenimine diazeniumdiolate |
WO2003080039A1 (en) | 2002-03-21 | 2003-10-02 | The University Of Utah Research Foundation | In vivo use of glutathionone s-transferase activated nitric oxide donors |
AU2003234510A1 (en) | 2002-05-07 | 2003-11-11 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Healt | Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxide release and related compounds, compositions comprising same and methods of using same |
CA2555591C (en) * | 2004-02-09 | 2011-01-04 | Amulet Pharmaceuticals, Inc. | Nitric oxide-releasing polymers |
US20080305082A1 (en) * | 2004-09-14 | 2008-12-11 | Curd John G | 1,4-Bis-N-Oxide-5,8- Dihydroxyanthracenedione Compounds and the Use Thereof |
SI1933821T1 (en) | 2005-09-15 | 2020-11-30 | Ptc Therapeutics, Inc. | Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
DE102007035323A1 (en) | 2007-07-25 | 2009-01-29 | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. -Hans-Knöll-Institut- | New diazen-1-ium-1,2-diolate substituted ketoconazole derivatives are ergosterol biosynthesis inhibitors useful as an active agent against microbial pathogenic germs, e.g. fungus, and an antiinflammatory active agent |
CN102014870A (en) | 2008-03-07 | 2011-04-13 | 犹他州大学研究基金会 | Activated nitric oxide donors and methods of making and using thereof |
KR101351130B1 (en) | 2012-11-05 | 2014-01-15 | 포항공과대학교 산학협력단 | Method for preparing coating film containing nitrogen monoxide using catecholamines in the surface of materials |
CN108712903A (en) | 2015-12-17 | 2018-10-26 | 生物电子技术有限公司 | Fluoroalkyl, fluoroalkyl, phenoxy group, heteroaryloxy, alkoxy and amine 1,4- quinone derivatives for treating oxidation emergency obstacle |
CN109053618B (en) * | 2018-02-22 | 2022-05-13 | 青岛科技大学 | Preparation method of oxazole derivative |
CN112939886B (en) * | 2021-02-04 | 2022-05-31 | 山西大学 | Near-infrared fluorescent probe capable of detecting content of GSTs (glutathione S-terminal transferase) as well as synthetic method and application thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5405919A (en) * | 1992-08-24 | 1995-04-11 | The United States Of America As Represented By The Secretary Of Health And Human Services | Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders |
WO1998013358A1 (en) * | 1996-09-27 | 1998-04-02 | The United States Of America Represented By The Secretary, Department Of Health And Human Services | O2-arylated or o2-glycosylated 1-substituted diazen-1-ium-1,2-diolates and o2-substituted 1-[(2-carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolates |
-
2001
- 2001-06-01 WO PCT/US2001/017868 patent/WO2001092215A2/en active Application Filing
- 2001-07-01 AU AU2001275155A patent/AU2001275155A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5405919A (en) * | 1992-08-24 | 1995-04-11 | The United States Of America As Represented By The Secretary Of Health And Human Services | Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders |
WO1998013358A1 (en) * | 1996-09-27 | 1998-04-02 | The United States Of America Represented By The Secretary, Department Of Health And Human Services | O2-arylated or o2-glycosylated 1-substituted diazen-1-ium-1,2-diolates and o2-substituted 1-[(2-carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolates |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9447006B2 (en) | 2005-06-01 | 2016-09-20 | Edison Pharmaceuticals, Inc. | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
US9278085B2 (en) | 2006-02-22 | 2016-03-08 | Edison Pharmaceuticals, Inc. | Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
US9399612B2 (en) | 2008-09-10 | 2016-07-26 | Edison Pharmaceuticals, Inc. | Treatment of pervasive developmental disorders with redox-active therapeutics |
Also Published As
Publication number | Publication date |
---|---|
WO2001092215A2 (en) | 2001-12-06 |
AU2001275155A1 (en) | 2001-12-11 |
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