WO2002000817A1 - Wipe with improved cleansing - Google Patents

Wipe with improved cleansing Download PDF

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Publication number
WO2002000817A1
WO2002000817A1 PCT/US2001/020255 US0120255W WO0200817A1 WO 2002000817 A1 WO2002000817 A1 WO 2002000817A1 US 0120255 W US0120255 W US 0120255W WO 0200817 A1 WO0200817 A1 WO 0200817A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition
wipe
peg
glyceryl cocoate
present
Prior art date
Application number
PCT/US2001/020255
Other languages
French (fr)
Inventor
Catherine Durden
Original Assignee
Playtex Products, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Playtex Products, Inc. filed Critical Playtex Products, Inc.
Priority to AU2001270161A priority Critical patent/AU2001270161B2/en
Priority to AU7016101A priority patent/AU7016101A/en
Priority to CA2413889A priority patent/CA2413889C/en
Publication of WO2002000817A1 publication Critical patent/WO2002000817A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/88—Ampholytes; Electroneutral compounds
    • C11D1/94—Mixtures with anionic, cationic or non-ionic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/04—Detergent materials or soaps characterised by their shape or physical properties combined with or containing other objects
    • C11D17/041—Compositions releasably affixed on a substrate or incorporated into a dispensing means
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/04—Detergent materials or soaps characterised by their shape or physical properties combined with or containing other objects
    • C11D17/049—Cleaning or scouring pads; Wipes
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/74—Carboxylates or sulfonates esters of polyoxyalkylene glycols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/88—Ampholytes; Electroneutral compounds
    • C11D1/90—Betaines

Definitions

  • the present invention relates to a formulation for a wipe. More particularly, the present invention relates to a wipe or towelette formulation that has improved cleaning or cleansing ability. The wipe is particularly useful for cleaning a diaper area of a baby or an infant because of the mildness of the formulation.
  • a towelette or wipe is generally an absorbent sheet that is treated or pre- moistened with a liquid formulation.
  • the liquid employed in pre-moistening the sheet is generally an aqueous solution.
  • the solution may have a surface active detergent, a humectant and, in some instances, also a fragrance.
  • Typical baby wipe liquid formulations have water, propylene glycol, a mild surfactant, a lanolin derivative, one or more preservatives and other desired additives, such as a fragrance or botanical. Such formulations have an acceptable level of cleaning, with little consumer dissatisfaction.
  • the pre-moistened towelette has its liquid work in conjunction with the fabric to cleanse the diaper area of urine and fecal matter. It is believed that the fabric, by virtue of being wet, is what contributes significantly to the cleansing ability of the towelette. In other words, the texture of the fabric or substrate contributes more to cleansing than the actual ingredients in the liquid.
  • little emphasis has been placed on the combination of ingredients in the liquid to enhance the cleansing ability of a wipe, especially a baby or infant wipe.
  • U.S. Patents Nos. 4,741,944 and 4,865,221 to Jackson et al provide wet wipes having a liquid in the sheet and/or web.
  • the liquid includes water, benzalkonium chloride, citric acid, disodium phosphate, trisodium ethylene diamine tetraacetic acid, polyethylene glycol-75 lanolin, cocoamphocarboxyglycinate, propylene glycol, methylparaben, propylparaben, butylparaben, polysorbate 20 and fragrance.
  • the Jackson et al. patents focus on an improved fabric that is interweaved in a manner so as to facilitate dispensing of each wipe from the container.
  • U.S. Patents Nos. 4,732,797 and 4,772,501 to Johnson et al. are directed to a natural acid preservation system for a wet wipe that consists of citric acid and sorbic acid.
  • U.S. Patent No. 5,141,803 to Pregozen provides a nonwoven wipe impregnating composition.
  • a specific cationic biocide is included in the preservative system.
  • the cationic biocide, polyhexamethylene biguanide hydrochloride allegedly greatly minimizes the slippery feel of the wet wipe.
  • U.S. Patent No. 4,737,405 to Bouchette is directed to a binder catalyst for an antimicrobially active, non-woven web.
  • U.S. Patent No. 4,781,974 to Bouchette et al. is directed to an antimicrobially active wet wipe having an antimicrobially active, non-woven web and a liquid containing a second antimicrobial agent.
  • U.S. Patent No. 5,512,199 to Khan et al. is directed to a hand wipe that includes an alcohol, an antimicrobial agent, a water soluble polymer, a polyalkylene glycol and a moisturizer and/or emollient, along with water.
  • U.S. Patent No. 5,152,996 to Corey et al. is directed to a nonwoven wipe impregnated with an aqueous solution of a zinc acetate peroxide and a surfactant.
  • U.S. Patent No. 5,256,417 to Koltisko is directed to a water dispersible towelette impregnated with non-aqueous lotion formulations.
  • the towelette was made of nonwoven fibers coated or impregnated with a polyvinyl alcohol or an emulsion polymer binder to impart wet strength.
  • U.S. Patent No. 5,648,083 to Blieszner et al. is directed to a wet wipe that has silicone oil and a polymeric emulsifier.
  • U.S. Patent No. 5,753,246 to Peters is directed to a packaged germicidal towelette that has aloe vera and cocoa butter, as well as a chlorhexidine alcohol solution.
  • the present invention is a liquid wipe formulation that has surprisingly better cleansing ability than a typical liquid wipe formulation when used on the same fabric or substrate.
  • the surprisingly better cleansing ability is achieved by the unique combination of surfactants found in the subject wipe, preferably a baby wipe.
  • the present liquid wipe formulation has the same or increased mildness than the typical liquid wipe formulations. Still further, the present formulation does not cause skin irritation.
  • the cleansing agents may include either (1) cocamidopropyl betaine, or (2) PEG-80 glyceryl cocoate and PEG-30 glyceryl cocoate, but has been found that the combination of both has enhanced cleansing ability.
  • a liquid or aqueous wipe composition comprising two cleansing agents, namely cocamidopropyl betaine, and PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate.
  • the composition may further include a solvent, such as water, a humectant, a fragrance, a skin conditioning agent, a preservative, a chelating agent, a salt, and/or a pH adjuster.
  • the present invention is a liquid wipe formulation used primarily in a baby or infant wipe.
  • the combination of two cleansing agents has been found to have a surprisingly unexpected cleaning ability, especially for urine and fecal matter.
  • the first cleansing agent is cocamidopropyl betaine.
  • This ingredient also acts as a skin conditioning agent.
  • the cocamidopropyl betaine is present in an amount up to about 0.25 wt% of the total weight of the liquid composition. Preferably, it is in an amount about 0.15 wt%.
  • the second cleansing agent is a glyceryl cocoate having the formula: O
  • the preferred second cleansing agent is a mixture of glyceryl cocoate wherein n is 30 and 80 (PEG-30 glyceryl cocoate and PEG-80 glyceryl cocoate respectively).
  • this second cleansing agent is present in an amount up to about 0.25 wt% of the total weight of the liquid composition. Preferably, it is present in an amount about 0.15 wt%.
  • the first and second cleansing agents are known as surfactants. It is believed that either one of the above-described cleansing agents alone may improve cleansing ability. It is also believed that the first cleansing agent (cocamidopropyl betaine) may be added to either component of the second cleansing agent (PEG-80 glyceryl cocoate or PEG-30 glyceryl cocoate) to improve cleansing ability. Besides the two cleansing agents, additional cleansing agents may be used in the present composition. For example, disodium cocoamphodiacetate may be present in an amount up to about 0.10 wt% of the total weight of the liquid composition. Also, decyl polyglucose may be present in addition to or instead of the disodium cocoamphodiacetate, and in an amount up to about 0.10 wt%. Again, these additional cleansing agents may be surfactants.
  • the total surfactants namely disodium cocoamphodiacetate, cocamidopropyl betaine, PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate, and decyl polyglucose, must be a minimum of about 0.20 wt% of the total weight of the liquid composition.
  • the present composition may include one or more of the following: a solvent, a humectant, a fragrance, a skin conditioning agent, a preservative, a chelating agent, a salt and/or a pH adjuster.
  • the preferred solvent is water. Water is preferably present in an amount from about 50 wt% to about 98 wt% of the total weight of the liquid composition.
  • the humectant is preferably one or more of the following: glycerol, propylene glycol, sorbitol urea, amino acids, certain polyols and other compounds with hygroscopic properties.
  • the preferred humectant is propylene glycol.
  • the humectant is preferably present in an amount from about 0.10 wt% up to about 1 wt% of the total weight of the liquid composition. More preferably, the humectant is present in an amount about 0.50 wt%.
  • the composition may include a fragrance. Any conventional fragrance that does not adversely affect an infant or baby may be used.
  • the fragrance is present in an amount from about 0 wt% up to about 0.20 wt%, and more preferably about 0.05 wt% of the total weight of the liquid composition.
  • the skin conditioning agent is preferably one or more of the following: botanical extracts including aloe vera gel, esters including tocopherol acetate, quaternary ammonium compounds, asymmetrical carbonates, N-substituted carboxamides, ureas or phosphine oxides, and organic salts.
  • the preferred skin conditioning agent is aloe vera gel.
  • the skin conditioning agent is preferably present in an amount from about 0 wt% up to about 1 wt% of the total weight of the liquid composition. More preferably, it is present in an amount about 0.01 wt%.
  • the preservative is preferably one or more of the following: sodium hydroxymethylglycinate, polyaminopropyl biguanide, quaternary ammonium compounds, EDTA salts, EDTA fatty acid conjugates, alkanols especially ethanol, isopropyl alcohol, benzyl alcohol, parabens, sorbates, urea derivatives, and isothiazolinone, or mixtures thereof.
  • the preferred preservative is sodium hydroxymethylglycinate.
  • the preservative is preferably present in an amount from about 0.5 wt% to about 2 wt% of the weight of the liquid composition, and more preferably about 0.5 wt%.
  • the chelating agent is preferably one or more of the following: disodium
  • EDTA ethylenediamine tetraacetate
  • ethylene-diamine-tetra-acetic acid ethylenedioxy-diethylene-dinitrilo-tetra-acetic acid
  • salicylaldoxime quinolinol
  • triethylenetetramine triethylenetetramine, or mixtures thereof.
  • the preferred chelating agent is disodium EDTA.
  • the chelating agent is preferably present in an amount from about 0 wt% up to about 0.2 wt% of the total weight of the liquid composition. More preferably, the chelating agent is present in an amount about 0.10 wt%.
  • the salt is preferably potassium sorbate or any organic acid such as malic acid or benzoic acid.
  • Potassium sorbate also acts as a preservative. Preferably, it is present in an amount about 0.10 wt% to about 0.30 wt%, and more preferably about 0.14 wt% of the total weight of the liquid composition.
  • the preferred pH adjuster is citric acid.
  • citric acid is present in an amount from about 0.10 wt% to about 0.30 wt% of the total weight of the liquid composition. More preferably, the citric acid is present in an amount about 0.20 wt%.
  • a preferred composition according to the present invention is a baby or infant wipe composition
  • a baby or infant wipe composition comprising: water; and cocamidopropyl betaine and PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate, each in an amount from about 0 wt% to about 0.25 wt%, with the total amount being at least about 0.20 wt% of the total weight of the liquid composition.
  • the composition may also include propylene glycol in an amount from about 0.1 wt% up to about 1 wt%; fragrance in an amount from about 0 wt% up to about 0.20 wt%; and/or aloe vera gel in an amount from about 0 wt% up to about 1 wt%.
  • the composition may include disodium EDTA in an amount about 0 wt% up to about 0.20 wt%; and potassium sorbate in an amount from about 0.10 wt% to about 0.30 wt%, both of which act or have preservative properties and, optionally, citric acid in an amount about 0.10 wt% to about 0.30 wt% of the total weight of the liquid composition.
  • the subject liquid composition is listed in Table 1 in weight percents, along with a conventional formulation. This conventional formulation is used in the two experiments discussed below.
  • the total surfactant (disodium cocoamphodiacetate, cocamidopropyl betaine, PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate, and decyl polyglucose) must be a minimum of 0.20%.
  • the wipes for the conventional formulation and the improved cleansing subject composition are composed of 65 grams per square meter embossed, non- woven fabric.
  • the conventional wipe had the conventional formulation recited above.
  • the subject wipe had the subject composition recited above.
  • the difference between the two experiments is the labeling of the subject wipe.
  • the wipes with the subject composition were distributed to panelists using different labels (hereinafter, "Wipe with Subject Composition” in the first experiment) and (“Subject Composition Wipe” in the second experiment) in an attempt to unbias name recognition.
  • the panel was evenly split by the two brands the panelists used most often, that is between Brand A users and Brand B users.
  • Preference Summary also shows a significant difference favoring the wipe with the subject composition in both Brand A and Brand B users.
  • Tables 2 and 3 show that the improved cleansing wipe was preferred over both the conventional wipe and the brand that the consumer normally uses.
  • the consumer's normal wipe either Brand A or Brand B
  • has a different texture than the present wipe and yet the consumer perceived the present wipe as the better cleaner. This is unusual because texture is generally considered to be the primary contributor to cleansing ability.
  • the present invention has been proven to be a superior cleansing composition to conventional formulations that are currently commercially available.
  • surfactants such as cocamidopropyl betaine, and PEG- 80 glyceryl cocoate/PEG-30 glyceryl cocoate, surprisingly improves cleansing ability.
  • the two experiments clearly show evidence of a preference in a particular liquid formulation over another.
  • the experiments also show that consumers prefer the subject liquid composition to the consumer's usual brand.
  • the significance of consumer preference for a particular wipe due to the liquid formulation is a breakthrough in towelette development.

Abstract

The present invention relates to a liquid formulation for a baby wipe. The preferred formulation has cocamidopropyl betaine, and PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate.

Description

WIPE WITH IMPROVED CLEANSING
BACKGROUND OF THE INVENTION
1. Field Of The Invention
The present invention relates to a formulation for a wipe. More particularly, the present invention relates to a wipe or towelette formulation that has improved cleaning or cleansing ability. The wipe is particularly useful for cleaning a diaper area of a baby or an infant because of the mildness of the formulation.
2. Description of the Prior Art
A towelette or wipe is generally an absorbent sheet that is treated or pre- moistened with a liquid formulation. The liquid employed in pre-moistening the sheet is generally an aqueous solution. The solution may have a surface active detergent, a humectant and, in some instances, also a fragrance.
Typical baby wipe liquid formulations have water, propylene glycol, a mild surfactant, a lanolin derivative, one or more preservatives and other desired additives, such as a fragrance or botanical. Such formulations have an acceptable level of cleaning, with little consumer dissatisfaction. The pre-moistened towelette has its liquid work in conjunction with the fabric to cleanse the diaper area of urine and fecal matter. It is believed that the fabric, by virtue of being wet, is what contributes significantly to the cleansing ability of the towelette. In other words, the texture of the fabric or substrate contributes more to cleansing than the actual ingredients in the liquid. Heretofore, little emphasis has been placed on the combination of ingredients in the liquid to enhance the cleansing ability of a wipe, especially a baby or infant wipe.
For example, U.S. Patents Nos. 4,741,944 and 4,865,221 to Jackson et al, provide wet wipes having a liquid in the sheet and/or web. The liquid includes water, benzalkonium chloride, citric acid, disodium phosphate, trisodium ethylene diamine tetraacetic acid, polyethylene glycol-75 lanolin, cocoamphocarboxyglycinate, propylene glycol, methylparaben, propylparaben, butylparaben, polysorbate 20 and fragrance. The Jackson et al. patents focus on an improved fabric that is interweaved in a manner so as to facilitate dispensing of each wipe from the container.
U.S. Patents Nos. 4,732,797 and 4,772,501 to Johnson et al. are directed to a natural acid preservation system for a wet wipe that consists of citric acid and sorbic acid. U.S. Patent No. 5,141,803 to Pregozen provides a nonwoven wipe impregnating composition. A specific cationic biocide is included in the preservative system. The cationic biocide, polyhexamethylene biguanide hydrochloride, allegedly greatly minimizes the slippery feel of the wet wipe.
U.S. Patent No. 4,737,405 to Bouchette is directed to a binder catalyst for an antimicrobially active, non-woven web. Also, U.S. Patent No. 4,781,974 to Bouchette et al. is directed to an antimicrobially active wet wipe having an antimicrobially active, non-woven web and a liquid containing a second antimicrobial agent. U.S. Patent No. 5,512,199 to Khan et al. is directed to a hand wipe that includes an alcohol, an antimicrobial agent, a water soluble polymer, a polyalkylene glycol and a moisturizer and/or emollient, along with water.
Also, U.S. Patent No. 5,152,996 to Corey et al. is directed to a nonwoven wipe impregnated with an aqueous solution of a zinc acetate peroxide and a surfactant.
U.S. Patent No. 5,256,417 to Koltisko is directed to a water dispersible towelette impregnated with non-aqueous lotion formulations. The towelette was made of nonwoven fibers coated or impregnated with a polyvinyl alcohol or an emulsion polymer binder to impart wet strength.
U.S. Patent No. 5,648,083 to Blieszner et al. is directed to a wet wipe that has silicone oil and a polymeric emulsifier. U.S. Patent No. 5,753,246 to Peters is directed to a packaged germicidal towelette that has aloe vera and cocoa butter, as well as a chlorhexidine alcohol solution.
The present invention is a liquid wipe formulation that has surprisingly better cleansing ability than a typical liquid wipe formulation when used on the same fabric or substrate. The surprisingly better cleansing ability is achieved by the unique combination of surfactants found in the subject wipe, preferably a baby wipe. Also, the present liquid wipe formulation has the same or increased mildness than the typical liquid wipe formulations. Still further, the present formulation does not cause skin irritation. SUMMARY OF THE INVENTION
It is an object of the present invention to provide a liquid wipe formulation that has improved cleansing ability. It is another object of the present invention to provide such a wipe formulation that is mild and, thus, conducive for use in a baby or an infant wipe.
It is still another object of the present invention to provide such a wipe formulation that has a unique combination of cleansing agents.
It is yet another object of the present invention to provide such a wipe formulation in which the unique combination of cleansing agents is at least 0.20 percent by weight of the total weight of the composition.
It is a further object of the present invention to provide such a wipe formulation in which the cleansing agents may include either (1) cocamidopropyl betaine, or (2) PEG-80 glyceryl cocoate and PEG-30 glyceryl cocoate, but has been found that the combination of both has enhanced cleansing ability.
These and other objects of the present invention are achieved by the present invention that is a liquid or aqueous wipe composition comprising two cleansing agents, namely cocamidopropyl betaine, and PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate. The composition may further include a solvent, such as water, a humectant, a fragrance, a skin conditioning agent, a preservative, a chelating agent, a salt, and/or a pH adjuster.
DETAILED DESCRIPTION OF THE INVENTION
The present invention is a liquid wipe formulation used primarily in a baby or infant wipe. The combination of two cleansing agents has been found to have a surprisingly unexpected cleaning ability, especially for urine and fecal matter.
The first cleansing agent is cocamidopropyl betaine. This ingredient also acts as a skin conditioning agent. In the present invention, the cocamidopropyl betaine is present in an amount up to about 0.25 wt% of the total weight of the liquid composition. Preferably, it is in an amount about 0.15 wt%.
The second cleansing agent is a glyceryl cocoate having the formula: O
II RC- OCH2CHCH2(OCH2CH2)nOH
OH
where R represents a coconut fatty radical and n has a value from 20 to 100. The preferred second cleansing agent is a mixture of glyceryl cocoate wherein n is 30 and 80 (PEG-30 glyceryl cocoate and PEG-80 glyceryl cocoate respectively). In the present invention, this second cleansing agent is present in an amount up to about 0.25 wt% of the total weight of the liquid composition. Preferably, it is present in an amount about 0.15 wt%.
The first and second cleansing agents are known as surfactants. It is believed that either one of the above-described cleansing agents alone may improve cleansing ability. It is also believed that the first cleansing agent (cocamidopropyl betaine) may be added to either component of the second cleansing agent (PEG-80 glyceryl cocoate or PEG-30 glyceryl cocoate) to improve cleansing ability. Besides the two cleansing agents, additional cleansing agents may be used in the present composition. For example, disodium cocoamphodiacetate may be present in an amount up to about 0.10 wt% of the total weight of the liquid composition. Also, decyl polyglucose may be present in addition to or instead of the disodium cocoamphodiacetate, and in an amount up to about 0.10 wt%. Again, these additional cleansing agents may be surfactants.
The total surfactants, namely disodium cocoamphodiacetate, cocamidopropyl betaine, PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate, and decyl polyglucose, must be a minimum of about 0.20 wt% of the total weight of the liquid composition. Besides the cleansing agents discussed above, the present composition may include one or more of the following: a solvent, a humectant, a fragrance, a skin conditioning agent, a preservative, a chelating agent, a salt and/or a pH adjuster. The preferred solvent is water. Water is preferably present in an amount from about 50 wt% to about 98 wt% of the total weight of the liquid composition. The humectant is preferably one or more of the following: glycerol, propylene glycol, sorbitol urea, amino acids, certain polyols and other compounds with hygroscopic properties. The preferred humectant is propylene glycol. The humectant is preferably present in an amount from about 0.10 wt% up to about 1 wt% of the total weight of the liquid composition. More preferably, the humectant is present in an amount about 0.50 wt%. The composition may include a fragrance. Any conventional fragrance that does not adversely affect an infant or baby may be used. Preferably, the fragrance is present in an amount from about 0 wt% up to about 0.20 wt%, and more preferably about 0.05 wt% of the total weight of the liquid composition.
The skin conditioning agent is preferably one or more of the following: botanical extracts including aloe vera gel, esters including tocopherol acetate, quaternary ammonium compounds, asymmetrical carbonates, N-substituted carboxamides, ureas or phosphine oxides, and organic salts. The preferred skin conditioning agent is aloe vera gel. The skin conditioning agent is preferably present in an amount from about 0 wt% up to about 1 wt% of the total weight of the liquid composition. More preferably, it is present in an amount about 0.01 wt%.
The preservative is preferably one or more of the following: sodium hydroxymethylglycinate, polyaminopropyl biguanide, quaternary ammonium compounds, EDTA salts, EDTA fatty acid conjugates, alkanols especially ethanol, isopropyl alcohol, benzyl alcohol, parabens, sorbates, urea derivatives, and isothiazolinone, or mixtures thereof. The preferred preservative is sodium hydroxymethylglycinate. The preservative is preferably present in an amount from about 0.5 wt% to about 2 wt% of the weight of the liquid composition, and more preferably about 0.5 wt%. The chelating agent is preferably one or more of the following: disodium
EDTA (ethylenediamine tetraacetate), ethylene-diamine-tetra-acetic acid (ethylenedioxy)-diethylene-dinitrilo-tetra-acetic acid, salicylaldoxime, quinolinol, triethylenetetramine, or mixtures thereof. The preferred chelating agent is disodium EDTA. The chelating agent is preferably present in an amount from about 0 wt% up to about 0.2 wt% of the total weight of the liquid composition. More preferably, the chelating agent is present in an amount about 0.10 wt%.
The salt is preferably potassium sorbate or any organic acid such as malic acid or benzoic acid. Potassium sorbate also acts as a preservative. Preferably, it is present in an amount about 0.10 wt% to about 0.30 wt%, and more preferably about 0.14 wt% of the total weight of the liquid composition.
The preferred pH adjuster is citric acid. Preferably, citric acid is present in an amount from about 0.10 wt% to about 0.30 wt% of the total weight of the liquid composition. More preferably, the citric acid is present in an amount about 0.20 wt%.
Thus, a preferred composition according to the present invention is a baby or infant wipe composition comprising: water; and cocamidopropyl betaine and PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate, each in an amount from about 0 wt% to about 0.25 wt%, with the total amount being at least about 0.20 wt% of the total weight of the liquid composition. The composition may also include propylene glycol in an amount from about 0.1 wt% up to about 1 wt%; fragrance in an amount from about 0 wt% up to about 0.20 wt%; and/or aloe vera gel in an amount from about 0 wt% up to about 1 wt%. Yet further, the composition may include disodium EDTA in an amount about 0 wt% up to about 0.20 wt%; and potassium sorbate in an amount from about 0.10 wt% to about 0.30 wt%, both of which act or have preservative properties and, optionally, citric acid in an amount about 0.10 wt% to about 0.30 wt% of the total weight of the liquid composition.
The subject liquid composition is listed in Table 1 in weight percents, along with a conventional formulation. This conventional formulation is used in the two experiments discussed below.
Figure imgf000007_0001
Figure imgf000008_0001
The total surfactant (disodium cocoamphodiacetate, cocamidopropyl betaine, PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate, and decyl polyglucose) must be a minimum of 0.20%.
EXPERIMENTS
A skin irritation and sensitization test was performed on the present formulation using 200 subjects. No subjects developed an adverse reaction. Two Experiments were performed to compare the performance of the subject composition with both a conventional formulation and were questioned comparing both to the brand used most often by the panelists (either Brand A or Brand B).
The wipes for the conventional formulation and the improved cleansing subject composition are composed of 65 grams per square meter embossed, non- woven fabric. The conventional wipe had the conventional formulation recited above. The subject wipe had the subject composition recited above.
The difference between the two experiments is the labeling of the subject wipe. The wipes with the subject composition were distributed to panelists using different labels (hereinafter, "Wipe with Subject Composition" in the first experiment) and ("Subject Composition Wipe" in the second experiment) in an attempt to unbias name recognition.
For each experiment, there were fifty (50) panelists with children under three. Each panelist used each wipe (the conventional formulation and subject formulation) for one week.
The panel was evenly split by the two brands the panelists used most often, that is between Brand A users and Brand B users.
Table 2. Experiment !
Figure imgf000008_0002
Figure imgf000009_0001
*** = greater than 95% confidence limit
Note: totals do not equal 100 because of mixed replies by panelists
Table 4. Preference Summar
Figure imgf000009_0002
The results for each test were almost identical, regardless of the concept or labels, the panelist received. In both tests, the wipes with the subject composition were significantly preferred over the conventional wipe and the brand used most often by the panelists. The Preference Summary breaks down the wipe preference by the brands previously used by the consumers (Brand A and Brand B). The
Preference Summary also shows a significant difference favoring the wipe with the subject composition in both Brand A and Brand B users.
The results from this test confirm that wipes with the subject composition were preferred over both the selected conventional wipe and the panelist's current brand. The consumers' preference for the improved cleansing formula is surprising for two reasons. First, the conventional formula and the present composition were tested using the same fabric substrate. The actual differences between the conventional formulation and the composition of the present invention are small. Therefore, the consumer is perceiving only differences between the liquid formulations. Thus, the unique cleansing agents in the present composition lead to a dramatic change in consumer preference for cleansing ability. Also of note is the mildness and gentleness that the present wipe maintains, in order to compete and be chosen over the conventional wipes and brand used most often by panelists. Second, the consumer also perceives difference between the improved cleansing and the commercial wipe, which is the brand the consumer normally uses as shown in Table 4. Also, Tables 2 and 3 show that the improved cleansing wipe was preferred over both the conventional wipe and the brand that the consumer normally uses. In this case, the consumer's normal wipe (either Brand A or Brand B) has a different texture than the present wipe, and yet the consumer perceived the present wipe as the better cleaner. This is unusual because texture is generally considered to be the primary contributor to cleansing ability.
Thus, the present invention has been proven to be a superior cleansing composition to conventional formulations that are currently commercially available. The inclusion of surfactants such as cocamidopropyl betaine, and PEG- 80 glyceryl cocoate/PEG-30 glyceryl cocoate, surprisingly improves cleansing ability. The two experiments clearly show evidence of a preference in a particular liquid formulation over another. The experiments also show that consumers prefer the subject liquid composition to the consumer's usual brand. The significance of consumer preference for a particular wipe due to the liquid formulation is a breakthrough in towelette development.
It should be understood that the foregoing description is only illustrative of the present invention. Various alternatives and modifications can be devised by those skilled in the art without departing from the invention. Accordingly, the present invention is intended to embrace all such alternatives, modifications and variances which fall within the scope of the appended claims.

Claims

What is claimed is:
1. A liquid composition for a wipe comprising: cocamidopropyl betaine; and PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate.
2. The composition of claim 1, wherein said cocamidopropyl betaine is present in an amount from about 0 wt% up to about 0.25 wt% of the total weight of the liquid composition.
3. The composition of claim 1, wherein said cocamidopropyl betaine is present in an amount about 0.15 wt% of the total weight of the composition.
4. The composition of claim 1, wherein said PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate is present in an amount from about 0 wt% up to about 0.25 wt% of the total weight of the liquid composition.
5. The composition of claim 1, wherein said PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate is present in an amount about 0.15 wt% of the total weight of the composition.
6. The composition of claim 1, wherein said cocamidopropyl betaine and said PEG-80 glyceryl cocoate/PEG-30 glyceryl cocoate is at least 0.20 wt% of the total weight of the composition.
7. The composition of claim 1 , further comprising a solvent.
8. The composition of claim 1 , further comprising a humectant.
9. The composition of claim 8, wherein said humectant is present in an amount from about 0.10 wt% to about 1 wt% of the total weight of the composition.
10. The composition of claim 1, further comprising a skin conditioning agent.
11. The composition of claim 10, wherein said skin conditioning agent is aloe vera gel.
12. The composition of claim 10, wherein the skin conditioning agent is in an amount from about 0 wt% up to about 1 wt% of the total weight of the composition.
13. The composition of claim 1 , further comprising a preservative.
14. The composition of claim 13, wherein said preservative is sodium hydroxymethylglycinate.
15. The composition of claim 13 , wherein said preservative is in an amount from about 0.5 wt% to about 2 wt% of the total weight of the composition.
16. The composition of claim 1 , further comprising a pH adjuster.
17. The composition of claim 16, wherein said pH adjuster is in an amount from 0.J0 wt% to 0.30 wt% of the total weight of the composition.
18. The composition of claim 1, further comprising a chelating agent.
19. The composition of claim 18, wherein said chelating agent is in an amount from about 0 wt% up to about 0.2 wt% of the total weight of the composition.
20. The composition of claim 1 , further comprising a fragrance.
21. A liquid composition for a wipe comprising cocamidopropyl betaine.
22. The composition of claim 21, further comprising glyceryl cocoate having the formula:
O
II RC- OCH2CHCH2(OCH2CH2)nOH
OH
wherein R represents a coconut fatty radical and n has a value from 20 to 100.
23 , The composition of claim 21 , further comprising PEG-80 glyceryl cocoate.
24. The composition of claim 21, further comprising PEG 30 glyceryl cocoate.
25. A liquid composition for a wipe comprising PEG-80 glyceryl cocoate and PEG-30 glyceryl cocoate.
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