WO2002009729A3 - Treatment of hyperproliferative skin disorders and diseases - Google Patents

Treatment of hyperproliferative skin disorders and diseases Download PDF

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Publication number
WO2002009729A3
WO2002009729A3 PCT/CA2001/001078 CA0101078W WO0209729A3 WO 2002009729 A3 WO2002009729 A3 WO 2002009729A3 CA 0101078 W CA0101078 W CA 0101078W WO 0209729 A3 WO0209729 A3 WO 0209729A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
nanocrystalline
noble metals
hyperproliferative skin
diseases
Prior art date
Application number
PCT/CA2001/001078
Other languages
French (fr)
Other versions
WO2002009729A2 (en
Inventor
Robert Edward Burrell
John Barrymore Wright
Kan Lam
Original Assignee
Nucryst Pharm Corp
Robert Edward Burrell
John Barrymore Wright
Kan Lam
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nucryst Pharm Corp, Robert Edward Burrell, John Barrymore Wright, Kan Lam filed Critical Nucryst Pharm Corp
Priority to DE60107253T priority Critical patent/DE60107253T2/en
Priority to AU7832201A priority patent/AU7832201A/en
Priority to JP2002515282A priority patent/JP2004505057A/en
Priority to EP01956229A priority patent/EP1303283B1/en
Priority to CA002417279A priority patent/CA2417279C/en
Priority to AU2001278322A priority patent/AU2001278322B2/en
Priority to AT01956229T priority patent/ATE282420T1/en
Publication of WO2002009729A2 publication Critical patent/WO2002009729A2/en
Publication of WO2002009729A3 publication Critical patent/WO2002009729A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/38—Silver; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm

Abstract

The invention relates to the use of one or more noble metals selected from silver, gold, platinum, and palladium but most preferably silver, in a nanocrystalline form, for the treatment of a hyperproliferative skin disorder or disease such as psoriasis. Among the noble metals, silver is preferred for such treatment. The nanocrystalline noble metal of choice may be used in the form of a nanocrystalline coating of one or more noble metals, a nanocrystalline powder of one or more noble metals, or a solution containing dissolved species from a nanocrystalline powder or coating of one or more noble metals.
PCT/CA2001/001078 2000-07-27 2001-07-27 Treatment of hyperproliferative skin disorders and diseases WO2002009729A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE60107253T DE60107253T2 (en) 2000-07-27 2001-07-27 USE OF PRECIOUS METALS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF HYPERPROLIFERATIVE SKIN DISEASES AND DISEASES
AU7832201A AU7832201A (en) 2000-07-27 2001-07-27 Treatment of hyperproliferative skin disorders and diseases
JP2002515282A JP2004505057A (en) 2000-07-27 2001-07-27 Treatment of hyperproliferative skin disorders and diseases
EP01956229A EP1303283B1 (en) 2000-07-27 2001-07-27 Use of noble metals for the manufacture of a medicament to treat hyperproliferative skin disorders and diseases
CA002417279A CA2417279C (en) 2000-07-27 2001-07-27 Treatment of hyperproliferative skin disorders and diseases
AU2001278322A AU2001278322B2 (en) 2000-07-27 2001-07-27 Treatment of hyperproliferative skin disorders and diseases
AT01956229T ATE282420T1 (en) 2000-07-27 2001-07-27 USE OF PRECIOUS METALS FOR THE PRODUCTION OF A MEDICINAL PRODUCT FOR THE TREATMENT OF HYPERPROLIFERATIVE SKIN DISORDERS AND DISEASES

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62873500A 2000-07-27 2000-07-27
US09/628,735 2000-07-27

Publications (2)

Publication Number Publication Date
WO2002009729A2 WO2002009729A2 (en) 2002-02-07
WO2002009729A3 true WO2002009729A3 (en) 2002-12-12

Family

ID=24520081

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2001/001078 WO2002009729A2 (en) 2000-07-27 2001-07-27 Treatment of hyperproliferative skin disorders and diseases

Country Status (9)

Country Link
US (1) US6692773B2 (en)
EP (1) EP1303283B1 (en)
JP (1) JP2004505057A (en)
AT (1) ATE282420T1 (en)
AU (2) AU7832201A (en)
CA (1) CA2417279C (en)
DE (1) DE60107253T2 (en)
ES (1) ES2231528T3 (en)
WO (1) WO2002009729A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8865227B2 (en) 2007-12-20 2014-10-21 Smith & Nephew (Overseas) Limited Metal carbonate particles and methods of making thereof

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1041879B2 (en) 1997-10-10 2012-03-21 Pure Bioscience Disinfectant and method of making
US7261905B2 (en) * 1999-04-07 2007-08-28 Pure Bioscience Disinfectant and method of making
US7137968B1 (en) * 2000-03-13 2006-11-21 Nucryst Pharmaceuticals Corp. Transcutaneous medical device dressings and method of use
US6890953B2 (en) * 2000-04-06 2005-05-10 Innovative Medical Services Process for treating water
US6719987B2 (en) 2000-04-17 2004-04-13 Nucryst Pharmaceuticals Corp. Antimicrobial bioabsorbable materials
US20030194444A1 (en) * 2000-07-27 2003-10-16 Burrell Robert E. Methods of treating skin and integument conditions
US7008647B2 (en) * 2001-04-23 2006-03-07 Nucryst Pharmaceuticals Corp. Treatment of acne
US7001617B2 (en) 2001-04-23 2006-02-21 Nueryst Pharmaceuticals Corp. Method of induction of apoptosis and inhibition of matrix metalloproteinases using antimicrobial metals
US6989157B2 (en) * 2000-07-27 2006-01-24 Nucryst Pharmaceuticals Corp. Dry powders of metal-containing compounds
US20030170314A1 (en) * 2000-07-27 2003-09-11 Burrell Robert E. Compositions of metal-containing compounds
US7427416B2 (en) * 2000-07-27 2008-09-23 Nucryst Pharmaceuticals Corp. Methods of treating conditions using metal-containing materials
US20030180379A1 (en) * 2000-07-27 2003-09-25 Burrell Robert E. Solutions and aerosols of metal-containing compounds
US7255881B2 (en) * 2000-07-27 2007-08-14 Nucryst Pharmaceuticals Corp. Metal-containing materials
AU7832201A (en) 2000-07-27 2002-02-13 Nucryst Pharm Corp Treatment of hyperproliferative skin disorders and diseases
US20040191329A1 (en) * 2000-07-27 2004-09-30 Burrell Robert E. Compositions and methods of metal-containing materials
US20030185901A1 (en) * 2000-07-27 2003-10-02 Burrell Robert E. Methods of treating conditions with a metal-containing material
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
ATE322274T1 (en) * 2001-04-23 2006-04-15 Nucryst Pharm Corp MEDICINAL PRODUCTS OR PLASTERS CONTAINING A METAL SUCH AS SILVER GOLD, PLATINUM OR PALLADIUM AS AN ANTIMICROBIAL ACTIVE AND THEIR USE IN THE TREATMENT OF SKIN INFLAMMATION
US6830565B2 (en) * 2001-05-04 2004-12-14 Hollister Incorporated Adhesive faceplate for ostomy appliance having mirrored release sheet
US7201925B2 (en) * 2002-04-23 2007-04-10 Nueryst Pharmaceuticals Corp. Treatment of ungual and subungual diseases
GEP20074134B (en) * 2002-08-19 2007-06-25 Pfizer Prod Inc Combination therapy for hyperproliferative diseases
US20040044073A1 (en) * 2002-08-31 2004-03-04 Innovative Medical Services Composition and process for treating acne
AU2003286575A1 (en) * 2002-10-22 2004-05-13 Nucryst Pharmaceuticals Corp. Prophylactic treatment methods
US7435438B1 (en) 2003-05-16 2008-10-14 Pure Bioscience Disinfectant and method of use
CA2678624C (en) * 2003-05-16 2012-11-06 Exciton Technologies Inc. Deposition products, composite materials and processes for the production thereof
WO2004105586A2 (en) * 2003-05-27 2004-12-09 Azna Health And Wellness Inc. Light wand for healing tissue
WO2004112852A1 (en) * 2003-06-23 2004-12-29 Beiersdorf Ag Antimicrobial wounddressing
DE10328261B4 (en) 2003-06-23 2007-10-25 Beiersdorf Ag Disinfecting coating with silver coating and its use
AU2004267997B2 (en) * 2003-08-28 2010-06-03 Pure Bioscience Silver dihydrogen citrate compositions comprising a second antimicrobial agent
GB0401821D0 (en) * 2004-01-28 2004-03-03 Qinetiq Nanomaterials Ltd Method of manufacture of polymer composites
CA2458110A1 (en) * 2004-02-19 2005-08-19 Mbec Bioproducts Inc. Composition and method for preserving plant material
US20060051430A1 (en) * 2004-09-07 2006-03-09 Arata Andrew B Silver dihydrogen citrate compositions
GB0422525D0 (en) 2004-10-11 2004-11-10 Luebcke Peter Dermatological compositions and methods
KR20080030548A (en) * 2004-12-06 2008-04-04 노바센트릭스, 인코포레이티드 Anti-viral uses of metal nanomaterial compositions
DE102005041005B4 (en) 2005-08-29 2022-10-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Biocidal composition containing nanoparticulate silver, the use of this composition and a method for the production of biocidal products using this composition
GB2432529B (en) 2005-11-25 2008-04-23 Univ Feng Chia Antimicrobial compositions and wound dressings
US7517536B2 (en) 2005-11-25 2009-04-14 Feng Chia University Antimicrobial compositions and wound dressings
US20080014278A1 (en) * 2006-06-30 2008-01-17 Nucryst Pharmaceuticals Metal-containing formulations and methods of use
DE102008031023A1 (en) 2008-06-30 2009-12-31 Neubourg Skin Care Gmbh & Co. Kg Foam skin care cream
EP2457572A1 (en) * 2010-11-05 2012-05-30 Universidade De Santiago De Compostela Use of atomic quantum clusters (aqcs) in the prevention of cell proliferative disorders, viral infections and autoimmune diseases
GB2511528A (en) 2013-03-06 2014-09-10 Speciality Fibres And Materials Ltd Absorbent materials
DE102014210909B4 (en) 2014-06-06 2019-03-07 Skf Lubrication Systems Germany Ag lubricant pump
CN116059244B (en) * 2023-02-27 2024-02-20 中南大学湘雅医院 Use of platinum nanowires as active ingredients in the treatment of skin disorders

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996017595A1 (en) * 1994-12-06 1996-06-13 Giltech Limited Foamable formulation and foam
DE19541735A1 (en) * 1995-11-09 1997-05-15 Iris Roller Use of hydrothermal rock deposits e.g. calcite precursors

Family Cites Families (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB420052A (en) 1932-10-17 1934-11-23 Consortium Elektrochem Ind Manufacture of shaped articles from polyvinyl alcohols
FR732895A (en) 1932-10-18 1932-09-25 Consortium Elektrochem Ind Articles spun in polyvinyl alcohol
FR882M (en) 1961-01-18 1961-10-06
GB1270410A (en) 1969-09-25 1972-04-12 Allor Corp Colloidal composition and method of preparing the same
US3757786A (en) 1970-11-06 1973-09-11 D Smith Synthetic surgical sutures
US3800792A (en) 1972-04-17 1974-04-02 Johnson & Johnson Laminated collagen film dressing
US3918446A (en) 1974-05-03 1975-11-11 E Med Corp Securement device for intravenous catheter and its tubing
US4059105A (en) 1976-03-24 1977-11-22 Omnimed, Inc. Cannula securing device
DE2748882A1 (en) 1977-11-02 1979-05-03 Arnis Dr Med Rava Plaster protecting wound against infection - esp. during application of intravenous catheter, permitting continuous use for ten days
DE2929706C2 (en) 1979-07-21 1982-09-30 Drägerwerk AG, 2400 Lübeck Breathing air humidifiers and warmers for ventilation systems
US4324237A (en) 1980-02-26 1982-04-13 E-Med Corporation Intravenous catheter and tubing securement and dressing device with a window over the puncture or wound site
GB2073024B (en) 1980-03-27 1984-06-27 Nat Res Dev Antimicrobial surgical implants
WO1981002667A1 (en) 1980-03-27 1981-10-01 Nat Res Dev Antimicrobial surgical implants
GB2140684B (en) 1983-04-25 1986-07-30 Stavros Christodoulou Mineral oil composition for use in the treatment of eczema
US4828832A (en) 1983-09-07 1989-05-09 Laboratorios Biochemie De Mexico Method of manufacturing a composition for treating skin lesions
EP0136768A3 (en) 1983-09-07 1986-07-30 Laboratorios Biochemie De Mexico S.A. DE C.V. Composition and method for treatingskin lesions
US4581028A (en) 1984-04-30 1986-04-08 The Trustees Of Columbia University In The City Of New York Infection-resistant materials and method of making same through use of sulfonamides
GB8421706D0 (en) 1984-08-28 1984-10-03 Pharmaceutical Holdings Ltd Pharmaceutical preparations
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
US4633863A (en) 1985-09-27 1987-01-06 Filips Chester P Arterial anchor bandage
US4960413A (en) 1985-11-09 1990-10-02 The Shirley Institute Wound dressing
US5122418A (en) 1985-12-09 1992-06-16 Shiseido Company Ltd. Composite powder and production process
US4847049A (en) 1985-12-18 1989-07-11 Vitaphore Corporation Method of forming chelated collagen having bactericidal properties
GB8607159D0 (en) 1986-03-22 1986-04-30 Smith & Nephew Ass Pharmaceutical composition
US5236421A (en) 1986-05-28 1993-08-17 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Fixing system for fastening catheters, cannulas or the like to the skin surface and process for the sterile fastening thereof
EP0254413A3 (en) 1986-06-13 1989-11-08 Yoshiaki Matsuo Silver-ionic water and its uses
US4952411A (en) 1987-02-25 1990-08-28 Trustees Of Columbia University In The City Of New York Method of inhibiting the transmission of AIDS virus
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US5143717A (en) 1987-12-30 1992-09-01 Code Blue Medical Corporation Burn foam and delivery system
US5019096A (en) 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
DE3807944A1 (en) 1988-03-10 1989-09-21 Braun Melsungen Ag Device for fastening a catheter or a cannula on the skin surface
US4956350A (en) 1988-08-18 1990-09-11 Minnesota Mining And Manufacturing Company Wound filling compositions
EP0355009A1 (en) 1988-08-18 1990-02-21 Konrad Minninger Silver sulfadiazine containing pharmaceutical product for the local external therapy
US4908355A (en) 1989-01-09 1990-03-13 Dow Corning Corporation Skin treatment method
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5270358A (en) 1989-12-28 1993-12-14 Minnesota Mining And Manufacturing Company Composite of a disperesed gel in an adhesive matrix
US5348799A (en) 1991-09-03 1994-09-20 Minnesota Mining And Manufacturing Company Antistatic coatings comprising chitosan acid salt and metal oxide particles
US5681575A (en) 1992-05-19 1997-10-28 Westaim Technologies Inc. Anti-microbial coating for medical devices
GEP20002074B (en) 1992-05-19 2000-05-10 Westaim Tech Inc Ca Modified Material and Method for its Production
USD349958S (en) 1992-07-24 1994-08-23 Bioject Inc. Needleless injector
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
CN1034090C (en) 1992-08-06 1997-02-19 蒋建华 Long-acting broad-spectrum antiseptic fabric and its producing method
IT1256111B (en) 1992-11-23 1995-11-28 Lifegroup Spa SALTS OF TRAUMATIC ACID WITH CICATRIZING AND ANTIBACTERIAL ACTIVITY
JP2981528B2 (en) 1992-12-25 1999-11-22 三菱電機株式会社 Cathode ray tube and method of manufacturing the same
US5631066A (en) 1993-01-25 1997-05-20 Chronopol, Inc. Process for making metalized films and films produced therefrom
US5534288A (en) 1993-03-23 1996-07-09 United States Surgical Corporation Infection-resistant surgical devices and methods of making them
US5848995A (en) 1993-04-09 1998-12-15 Walder; Anthony J. Anti-infective medical article and method for its preparation
US5454889A (en) 1993-08-19 1995-10-03 Ici Canada Inc. Prill coating
EP0727427A4 (en) 1993-11-05 1997-10-15 Meiji Milk Prod Co Ltd Antibacterial, antifungal and antiviral agent
US5454886A (en) 1993-11-18 1995-10-03 Westaim Technologies Inc. Process of activating anti-microbial materials
US5372589A (en) 1993-11-24 1994-12-13 Davis; W. Gordon Fenestrated transparent catheter securing device and method
EP0681841A1 (en) 1993-11-26 1995-11-15 Kimurakogyo Co., Ltd. $i(IN VIVO) FREE-RADICAL GENERATOR
US5817325A (en) 1996-10-28 1998-10-06 Biopolymerix, Inc. Contact-killing antimicrobial devices
US5899880A (en) 1994-04-08 1999-05-04 Powderject Research Limited Needleless syringe using supersonic gas flow for particle delivery
US5563132A (en) 1994-06-21 1996-10-08 Bodaness; Richard S. Two-step cancer treatment method
US5578073A (en) 1994-09-16 1996-11-26 Ramot Of Tel Aviv University Thromboresistant surface treatment for biomaterials
US5569207A (en) 1994-10-13 1996-10-29 Quinton Instrument Company Hydrocolloid dressing
US5589177A (en) 1994-12-06 1996-12-31 Helene Curtis, Inc. Rinse-off water-in-oil-in-water compositions
GB9502879D0 (en) 1995-02-14 1995-04-05 Oxford Biosciences Ltd Particle delivery
WO1996040171A1 (en) 1995-06-07 1996-12-19 Neuwirth Robert S Intrauterine chemical necrosing method and composition
CA2225808C (en) 1995-06-30 2002-12-17 Christopher C. Capelli Silver-based pharmaceutical compositions
US6013050A (en) 1995-10-20 2000-01-11 Powderject Research Limited Particle delivery
US5686096A (en) 1995-12-22 1997-11-11 Becton Dickinson And Company Medical device for the protection of a catheter penetration site
DE69728678T2 (en) 1996-07-11 2005-04-21 Coloplast As HYDROCOLLOID-WOUND GEL
DE19640365A1 (en) 1996-09-30 1998-04-02 Basf Ag Polymer-hydrogen peroxide complexes
US5895419A (en) 1996-09-30 1999-04-20 St. Jude Medical, Inc. Coated prosthetic cardiac device
US7625420B1 (en) 1997-02-24 2009-12-01 Cabot Corporation Copper powders methods for producing powders and devices fabricated from same
US6333093B1 (en) * 1997-03-17 2001-12-25 Westaim Biomedical Corp. Anti-microbial coatings having indicator properties and wound dressings
GB2324732B (en) 1997-05-02 2001-09-26 Johnson & Johnson Medical Absorbent wound dressings
US6071543A (en) 1997-06-02 2000-06-06 Cellegy Pharmaceuticals, Inc. Pyridine-thiols reverse mucocutaneous aging
KR20010013377A (en) 1997-06-04 2001-02-26 데이비드 엠 모이어 Mild, leave-on antimicrobial compositions
EP0991702B2 (en) 1997-06-20 2017-07-19 Coloplast A/S A hydrophilic coating
DE19728489A1 (en) 1997-07-03 1999-01-07 Huels Chemische Werke Ag Medical device for improving the skin fixation of indwelling catheters and other transcutaneous implants with a reduced risk of infection
US6165440A (en) 1997-07-09 2000-12-26 Board Of Regents, The University Of Texas System Radiation and nanoparticles for enhancement of drug delivery in solid tumors
US6123925A (en) 1998-07-27 2000-09-26 Healthshield Technologies L.L.C. Antibiotic toothpaste
US6071541A (en) 1998-07-31 2000-06-06 Murad; Howard Pharmaceutical compositions and methods for managing skin conditions
BR9915174A (en) 1998-11-09 2001-11-06 Ira Jay Newman Ionic silver complex
US6096002A (en) 1998-11-18 2000-08-01 Bioject, Inc. NGAS powered self-resetting needle-less hypodermic jet injection apparatus and method
US6365130B1 (en) 1998-11-23 2002-04-02 Agion Technologies L.L.C. Antimicrobial chewing gum
US6224579B1 (en) 1999-03-31 2001-05-01 The Trustees Of Columbia University In The City Of New York Triclosan and silver compound containing medical devices
US6258385B1 (en) 1999-04-22 2001-07-10 Marantech Holding, Llc Tetrasilver tetroxide treatment for skin conditions
JP4454062B2 (en) 1999-05-17 2010-04-21 敬 三宅 Ultrafine particle silver milky body and method for producing the same
CN1161511C (en) 1999-07-27 2004-08-11 蒋建华 Long-acting wide-spectrum antiseptic nanometer silver fabric and its making method
JP2001151681A (en) 1999-11-24 2001-06-05 Lintec Corp Prophylactic and/or therapeutic agent for systema digestorium disease
CN1108786C (en) 1999-12-28 2003-05-21 天津市化妆品科学技术研究所 Silver foil cosmetics
US6224898B1 (en) 2000-03-23 2001-05-01 The United States Of America As Represented By The Secretary Of The Army Antimicrobial dendrimer nanocomposites and a method of treating wounds
US6592888B1 (en) 2000-05-31 2003-07-15 Jentec, Inc. Composition for wound dressings safely using metallic compounds to produce anti-microbial properties
AU7832201A (en) 2000-07-27 2002-02-13 Nucryst Pharm Corp Treatment of hyperproliferative skin disorders and diseases
US7008647B2 (en) 2001-04-23 2006-03-07 Nucryst Pharmaceuticals Corp. Treatment of acne
DE10037353A1 (en) 2000-07-29 2002-02-07 Hans E Sachse Catheter with bioabsorbable coating to prevent rising infections
CN1279222A (en) 2000-07-31 2001-01-10 金华尖峰陶瓷有限责任公司 Antibacterial inorganic ceramics and its production technology
CN1291667A (en) 2000-08-14 2001-04-18 骏安科技投资有限公司 Nanometer silver anti-bacteria cloth and its industrial production technology
CN1147640C (en) 2000-09-19 2004-04-28 南京希科集团有限公司 Antibacterial fabric containing nm-class silver powder and its making method
CN1159488C (en) 2001-01-20 2004-07-28 南京希科集团有限公司 Antibacterial flexible material containing nm silver and its preparing process and application
CN1179646C (en) 2001-04-20 2004-12-15 朱红军 Aggregation-preventing nanometer wide-spectrum antibacterial silve powder and its inductrial production process
CN1183285C (en) 2001-04-25 2005-01-05 朱红军 Aggregation-preventing wide-spectrum nanometer antibiotic silver yarn and its industrial production process

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996017595A1 (en) * 1994-12-06 1996-06-13 Giltech Limited Foamable formulation and foam
DE19541735A1 (en) * 1995-11-09 1997-05-15 Iris Roller Use of hydrothermal rock deposits e.g. calcite precursors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8865227B2 (en) 2007-12-20 2014-10-21 Smith & Nephew (Overseas) Limited Metal carbonate particles and methods of making thereof

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DE60107253D1 (en) 2004-12-23
ATE282420T1 (en) 2004-12-15
EP1303283A2 (en) 2003-04-23
EP1303283B1 (en) 2004-11-17
WO2002009729A2 (en) 2002-02-07
DE60107253T2 (en) 2005-12-01
CA2417279A1 (en) 2002-02-07
AU2001278322B2 (en) 2005-12-22
CA2417279C (en) 2007-04-03
JP2004505057A (en) 2004-02-19
US6692773B2 (en) 2004-02-17
AU7832201A (en) 2002-02-13
ES2231528T3 (en) 2005-05-16

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