WO2002018609A3 - Methods for stable transduction of cells with viral vectors - Google Patents
Methods for stable transduction of cells with viral vectors Download PDFInfo
- Publication number
- WO2002018609A3 WO2002018609A3 PCT/US2001/027091 US0127091W WO0218609A3 WO 2002018609 A3 WO2002018609 A3 WO 2002018609A3 US 0127091 W US0127091 W US 0127091W WO 0218609 A3 WO0218609 A3 WO 0218609A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cells
- viral vectors
- methods
- transduced
- cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Abstract
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2003-7002964A KR20030074592A (en) | 2000-08-31 | 2001-08-29 | Methods for stable transduction of cells with viral vectors |
MXPA03001758A MXPA03001758A (en) | 2000-08-31 | 2001-08-29 | Methods for stable transduction of cells with viral vectors. |
NZ524642A NZ524642A (en) | 2000-08-31 | 2001-08-29 | Methods for stable transduction of cells with viral vectors |
AU2001286947A AU2001286947B2 (en) | 2000-08-31 | 2001-08-29 | Methods for stable transduction of cells with viral vectors |
JP2002522515A JP2004528806A (en) | 2000-08-31 | 2001-08-29 | Methods for stable transduction of cells using viral vectors |
AU8694701A AU8694701A (en) | 2000-08-31 | 2001-08-29 | Methods for stable transduction of cells with viral vectors |
IL15459901A IL154599A0 (en) | 2000-08-31 | 2001-08-29 | Methods for transduction of cells with viral vectors |
EP01966434A EP1315823A2 (en) | 2000-08-31 | 2001-08-29 | Methods for stable transduction of cells with viral vectors |
BR0113619-4A BR0113619A (en) | 2000-08-31 | 2001-08-29 | Methods for stable transduction of viral vector cells. |
CA2421063A CA2421063C (en) | 2000-08-31 | 2001-08-29 | Methods for stable transduction of cells with viral vectors |
NO20030901A NO20030901L (en) | 2000-08-31 | 2003-02-26 | Methods for stable transduction of cells with viral vectors |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/653,088 | 2000-08-31 | ||
US09/653,088 US6627442B1 (en) | 2000-08-31 | 2000-08-31 | Methods for stable transduction of cells with hiv-derived viral vectors |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2002018609A2 WO2002018609A2 (en) | 2002-03-07 |
WO2002018609A3 true WO2002018609A3 (en) | 2003-01-16 |
WO2002018609A9 WO2002018609A9 (en) | 2003-08-14 |
Family
ID=24619453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/027091 WO2002018609A2 (en) | 2000-08-31 | 2001-08-29 | Methods for stable transduction of cells with viral vectors |
Country Status (15)
Country | Link |
---|---|
US (2) | US6627442B1 (en) |
EP (2) | EP1315823A2 (en) |
JP (1) | JP2004528806A (en) |
KR (1) | KR20030074592A (en) |
CN (1) | CN100443593C (en) |
AU (2) | AU2001286947B2 (en) |
BR (1) | BR0113619A (en) |
CA (1) | CA2421063C (en) |
CZ (1) | CZ2003569A3 (en) |
IL (1) | IL154599A0 (en) |
MX (1) | MXPA03001758A (en) |
NO (1) | NO20030901L (en) |
NZ (1) | NZ524642A (en) |
RU (1) | RU2280074C2 (en) |
WO (1) | WO2002018609A2 (en) |
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2000
- 2000-08-31 US US09/653,088 patent/US6627442B1/en not_active Expired - Fee Related
-
2001
- 2001-08-29 BR BR0113619-4A patent/BR0113619A/en not_active Application Discontinuation
- 2001-08-29 CZ CZ2003569A patent/CZ2003569A3/en unknown
- 2001-08-29 CA CA2421063A patent/CA2421063C/en not_active Expired - Fee Related
- 2001-08-29 AU AU2001286947A patent/AU2001286947B2/en not_active Ceased
- 2001-08-29 KR KR10-2003-7002964A patent/KR20030074592A/en not_active Application Discontinuation
- 2001-08-29 RU RU2003108736/13A patent/RU2280074C2/en not_active IP Right Cessation
- 2001-08-29 JP JP2002522515A patent/JP2004528806A/en active Pending
- 2001-08-29 NZ NZ524642A patent/NZ524642A/en not_active IP Right Cessation
- 2001-08-29 MX MXPA03001758A patent/MXPA03001758A/en unknown
- 2001-08-29 WO PCT/US2001/027091 patent/WO2002018609A2/en active Application Filing
- 2001-08-29 EP EP01966434A patent/EP1315823A2/en not_active Ceased
- 2001-08-29 AU AU8694701A patent/AU8694701A/en active Pending
- 2001-08-29 IL IL15459901A patent/IL154599A0/en unknown
- 2001-08-29 EP EP08017638A patent/EP2031069A1/en not_active Withdrawn
- 2001-08-29 CN CNB018177255A patent/CN100443593C/en not_active Expired - Fee Related
-
2003
- 2003-02-26 NO NO20030901A patent/NO20030901L/en not_active Application Discontinuation
- 2003-09-16 US US10/664,331 patent/US20040062756A1/en not_active Abandoned
Patent Citations (1)
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WO1996034970A1 (en) * | 1995-05-04 | 1996-11-07 | United States Of America, Represented By The Secretary Of The Navy | Improved methods for transfecting t cells |
Non-Patent Citations (6)
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COSTELLO B. ET AL.: "GENE TRANSFER INTO STIMULATED AND UNSTIMULATED T LYMPHOCYTES BY HIV-1-DERIVED LENTIVIRAL VECTORS", GENE THERAPY, vol. 7, no. 7, April 2000 (2000-04-01), pages 596 - 604, XP001057677, ISSN: 0969-7128 * |
DOUGLAS J. ET AL.: "EFFICIENT TRANSDUCTION OF HUMAN LYMPHOCYTES AND CD34+ CELLS VIA HUMAN IMMUNODEFICIENCY VIRUS-BASED GENE TRANSFER VECTORS", HUMAN GENE THERAPY, vol. 10, no. 6, 10 April 1999 (1999-04-10), pages 935 - 945, XP000891430, ISSN: 1043-0342 * |
MOVASSAGH M. ET AL.: "HIGH LEVEL OF RETROVIRUS-MEDIATED GENE TRANSFER INTO DENDRITIC CELLS DERIVED FROM CORD BLOOD AND MOBILIZED PERIPHERAL BLOOD CD34+ CELLS", HUMAN GENE THERAPY, vol. 10, no. 2, 20 January 1999 (1999-01-20), pages 175 - 187, XP000960663, ISSN: 1043-0342 * |
NALDINI L. ET AL.: "IN VIVO GENE DELIVERY AND STABLE TRANSDUCTION OF NONDIVIDING CELLS BY A LENTIVIRAL VECTOR", SCIENCE, vol. 272, 12 April 1996 (1996-04-12), pages 263 - 267, XP000583652 * |
QUINN E. R. ET AL.: "T CELL ACTIVATION MODULATES RETROVIRUS-MEDIATED GENE EXPRESSION", HUMAN GENE THERAPY, vol. 9, no. 10, 1 July 1998 (1998-07-01), pages 1457 - 1467, XP001057661, ISSN: 1043-0342 * |
UCHIDA N. ET AL.: "HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G0/G1 human hematopoietic stem cells.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 95, no. 20, 29 September 1998 (1998-09-29), pages 11939 - 11944, XP002215385, ISSN: 0027-8424 * |
Also Published As
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CZ2003569A3 (en) | 2003-11-12 |
EP2031069A1 (en) | 2009-03-04 |
NO20030901D0 (en) | 2003-02-26 |
WO2002018609A9 (en) | 2003-08-14 |
KR20030074592A (en) | 2003-09-19 |
CA2421063C (en) | 2014-05-27 |
RU2280074C2 (en) | 2006-07-20 |
WO2002018609A2 (en) | 2002-03-07 |
JP2004528806A (en) | 2004-09-24 |
NZ524642A (en) | 2007-01-26 |
IL154599A0 (en) | 2003-09-17 |
US20040062756A1 (en) | 2004-04-01 |
EP1315823A2 (en) | 2003-06-04 |
CN1531596A (en) | 2004-09-22 |
US6627442B1 (en) | 2003-09-30 |
BR0113619A (en) | 2004-04-06 |
RU2003108736A (en) | 2005-02-10 |
MXPA03001758A (en) | 2004-11-01 |
AU8694701A (en) | 2002-03-13 |
CA2421063A1 (en) | 2002-03-07 |
CN100443593C (en) | 2008-12-17 |
AU2001286947B2 (en) | 2006-09-07 |
NO20030901L (en) | 2003-04-28 |
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