WO2002024048A3 - Apparatus and method for monitoring tissue vitality parameters - Google Patents

Apparatus and method for monitoring tissue vitality parameters Download PDF

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Publication number
WO2002024048A3
WO2002024048A3 PCT/IL2001/000906 IL0100906W WO0224048A3 WO 2002024048 A3 WO2002024048 A3 WO 2002024048A3 IL 0100906 W IL0100906 W IL 0100906W WO 0224048 A3 WO0224048 A3 WO 0224048A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
monitoring
illumination
collection fibers
illuminating
Prior art date
Application number
PCT/IL2001/000906
Other languages
French (fr)
Other versions
WO2002024048A2 (en
Inventor
Eliahu Pewzner
Avraham Mayevsky
Original Assignee
Vital Medical Ltd
Eliahu Pewzner
Avraham Mayevsky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vital Medical Ltd, Eliahu Pewzner, Avraham Mayevsky filed Critical Vital Medical Ltd
Priority to US10/381,383 priority Critical patent/US7130672B2/en
Priority to AU2001295848A priority patent/AU2001295848A1/en
Publication of WO2002024048A2 publication Critical patent/WO2002024048A2/en
Publication of WO2002024048A3 publication Critical patent/WO2002024048A3/en
Priority to US11/539,949 priority patent/US20070179366A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14553—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for cerebral tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
    • A61B2562/0242—Special features of optical sensors or probes classified in A61B5/00 for varying or adjusting the optical path length in the tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0261—Measuring blood flow using optical means, e.g. infrared light

Abstract

Apparatus for monitoring a plurality of tissue viability parameters of a tissue layer element, in which two different illumination sources are used via a common illumination element in contact with the tissue. One illumination source is used for monitoring blood flow rate and optionally flavoprotein concentration, and collection fibers are provided to receive the appropriate radiation from the tissue. The other illuminating radiation is used for monitoring any one of and preferably all of NADH, blood volume and blood oxygenation state of the tissue element, and collection fibers are provided to receive the appropriate radiation from the tissue. In one embodiment, the wavelengths of the two illumination sources are similar, and common collection fibers for the two illuminating radiations are used. In another embodiment, the respective collection fibers are distanced from the illumination point at different distances correlated to the ratio of the first and second illuminating wavelengths.
PCT/IL2001/000906 2000-09-25 2001-09-25 Apparatus and method for monitoring tissue vitality parameters WO2002024048A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/381,383 US7130672B2 (en) 2000-09-25 2001-09-25 Apparatus and method for monitoring tissue vitality parameters
AU2001295848A AU2001295848A1 (en) 2000-09-25 2001-09-25 Apparatus and method for monitoring tissue vitality parameters
US11/539,949 US20070179366A1 (en) 2000-09-25 2006-10-10 Apparatus and Method for Monitoring Tissue Vitality Parameters

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13868300A IL138683A0 (en) 2000-09-25 2000-09-25 Apparatus and method for monitoring tissue vitality parameters
IL138683 2000-09-25

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/539,949 Division US20070179366A1 (en) 2000-09-25 2006-10-10 Apparatus and Method for Monitoring Tissue Vitality Parameters

Publications (2)

Publication Number Publication Date
WO2002024048A2 WO2002024048A2 (en) 2002-03-28
WO2002024048A3 true WO2002024048A3 (en) 2002-07-18

Family

ID=11074672

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2001/000906 WO2002024048A2 (en) 2000-09-25 2001-09-25 Apparatus and method for monitoring tissue vitality parameters

Country Status (4)

Country Link
US (2) US7130672B2 (en)
AU (1) AU2001295848A1 (en)
IL (1) IL138683A0 (en)
WO (1) WO2002024048A2 (en)

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